Lista de obras - Angelo Sala - Dominio Público Uruguay

14,15-Dehydroleukotriene A4: a specific substrate for leukotriene C4 synthase

artículo científico publicado en 1997

15(S)-HETE modulates LTB(4) production and neutrophil chemotaxis in chronic bronchitis

artículo científico publicado en 2000

15-Lipoxygenase expression and 15(S)-hydroxyeicoisatetraenoic acid release and reincorporation in induced sputum of asthmatic subjects

artículo científico publicado en 2000

A new class of nitric oxide-releasing derivatives of cetirizine; pharmacological profile in vascular and airway smooth muscle preparations.

artículo científico publicado en 2007

Activation of the orphan nuclear receptor RORalpha counteracts the proliferative effect of fatty acids on prostate cancer cells: crucial role of 5-lipoxygenase.

artículo científico publicado en 2004

An improved assay for urinary LTE4

artículo científico publicado en 1994

Antagonism of thromboxane receptors by diclofenac and lumiracoxib

Antiinflammatory and antioxidant effects of H2O2 generated by natural sources in Il1β-treated human endothelial cells.

artículo científico publicado en 2015

Appearance of urinary metabolites of LTE4 in human subjects

artículo científico publicado en 1991

Autocrine activity of cysteinyl leukotrienes in human vascular endothelial cells: Signaling through the CysLT₂ receptor

artículo científico publicado en 2015

Azithromycin inhibits nuclear factor-κB activation during lung inflammation: an in vivo imaging study

artículo científico publicado en 2014

Beta2 integrin-dependent neutrophil adhesion induced by minimally modified low-density lipoproteins is mainly mediated by F2-isoprostanes

artículo científico publicado en 2002

Beta2-adrenergic activity modulates vascular tone regulation in lecithin:cholesterol acyltransferase knockout mice.

artículo científico publicado en 2015

Bioavailability of curcumin in the rat frontal lobe and hippocampus after repeated administration of MERIVA®

artículo científico publicado en 2016

Blood cell-vascular wall interactions and the production of coronary contracting sulfidopeptide leukotrienes in isolated, cell- perfused, rabbit heart

artículo científico publicado en 1995

Bronchodilators modulate inflammation in chronic obstructive pulmonary disease subjects

scientific article published on 31 May 2012

CHF6001 I: a novel highly potent and selective phosphodiesterase 4 inhibitor with robust anti-inflammatory activity and suitable for topical pulmonary administration

artículo científico publicado en 2015

CHF6001 II: a novel phosphodiesterase 4 inhibitor, suitable for topical pulmonary administration--in vivo preclinical pharmacology profile defines a potent anti-inflammatory compound with a wide therapeutic window

artículo científico publicado en 2015

Chronic obstructive pulmonary disease and neutrophil infiltration: role of cigarette smoke and cyclooxygenase products

artículo científico publicado en 2009

Comparative analysis of isolated human bronchi contraction and biosynthesis of cysteinyl leukotrienes using a direct 5-lipoxygenase inhibitor.

artículo científico publicado en 1997

Consequences of transcellular biosynthesis of leukotriene C4 on organ function

artículo científico publicado en 1996

Continuous wound infusion with chloroprocaine in a pig model of surgical lesion: drug absorption and effects on inflammatory response

artículo científico publicado en 2017

Corrigendum

scholarly article published in British Journal of Haematology

Corrigendum: Designing Multitarget Anti-inflammatory Agents: Chemical Modulation of the Lumiracoxib Structure toward Dual Thromboxane Antagonists-COX-2 Inhibitors

scholarly article by Massimo Bertinaria et al published 26 November 2012 in ChemMedChem

Critical role of COX-1 in prostacyclin production by human endothelial cells under modification of hydroperoxide tone

artículo científico publicado en 2008

Cyclooxygenase-1 and prostacyclin production by endothelial cells in the presence of mild oxidative stress

artículo científico publicado en 2013

Cyclooxygenase-2 and synthesis of PGE2 in human bronchial smooth-muscle cells

scientific article published on 01 March 1997

Cysteinyl leukotriene-1 receptor activation in a human bronchial epithelial cell line leads to signal transducer and activator of transcription 1-mediated eosinophil adhesion

artículo científico publicado en 2008

Cysteinyl-leukotrienes and their receptors in asthma and other inflammatory diseases: critical update and emerging trends.

artículo científico publicado en 2007

Cysteinyl-leukotrienes receptor activation in brain inflammatory reactions and cerebral edema formation: a role for transcellular biosynthesis of cysteinyl-leukotrienes

artículo científico publicado en 2004

Designing multitarget anti-inflammatory agents: chemical modulation of the lumiracoxib structure toward dual thromboxane antagonists-COX-2 inhibitors

artículo científico publicado en 2012

Differential effects of fluticasone propionate on allergen-evoked bronchoconstriction and increased urinary leukotriene E4 excretion

scientific article published on 01 July 1994

Differential metabolism of exogenous and endogenous arachidonic acid in human neutrophils

artículo científico publicado en 1999

Direct airway injury results in elevated levels of sulfidopeptide leukotrienes, detectable in airway secretions

artículo científico publicado en 1991

Dual COXIB/TP antagonists: a possible new twist in NSAID pharmacology and cardiovascular risk

artículo científico publicado en 2010

Effect of endogenous and exogenous prostaglandin E(2) on interleukin-1 beta-induced cyclooxygenase-2 expression in human airway smooth-muscle cells

artículo científico publicado en 2000

Effects of loratadine on cytosolic Ca2+ levels and leukotriene release: novel mechanisms of action independent of the anti-histamine activity

scientific article published on 01 February 1994

Effects of nedocromil sodium on bronchospasm and HS-NCA release induced by allergen inhalation in asthmatic patients

artículo científico publicado en 1994

Endothelial cells as target for antiphospholipid antibodies. Human Polyclonal and Monoclonal Anti-β2-Glycoprotein I Antibodies React In Vitro with Endothelial Cells Through Adherent β2-Glycoprotein I and Induce Endothelial Activation

scientific article published on 01 March 1997

Eosinophil 15-lipoxygenase is a leukotriene A4 synthase.

artículo científico publicado en 1994

Erratum to: Increased dietary levels of α-linolenic acid inhibit mammary tumor growth and metastasis

artículo científico publicado en 2016

Estrogen Receptor-α as a Drug Target Candidate for Preventing Lung Inflammation.

artículo científico publicado en 2009

Estrogen prevents the lipopolysaccharide-induced inflammatory response in microglia.

artículo científico publicado en 2001

Estrogen receptor-alpha as a drug target candidate for preventing lung inflammation

artículo científico publicado en 2009

Evidence of PAF-acether metabolic pathway activation in antigen challenge of upper respiratory airways.

artículo científico publicado en 1989

Exhaled and non-exhaled non-invasive markers for assessment of respiratory inflammation in patients with stable COPD and healthy smokers

artículo científico publicado en 2016

Formation of sulphidopeptide-leukotrienes by cell-cell interaction causes coronary vasoconstriction in isolated, cell-perfused heart of rabbit

artículo científico publicado en 1993

From field to health: a simple way to increase the nutraceutical content of grape as shown by NO-dependent vascular relaxation

artículo científico publicado en 2006

Furosemide attenuates bronchial responsiveness to antigen challenge "in vitro"

scientific article published on 01 January 1995

High urinary leukotriene E4 (LTE4) and thromboxane 2 (TXB2) levels are associated with capillary leak syndrome in bone marrow transplant patients

artículo científico publicado en 1991

IL-33/ST2 axis controls Th2/IL-31 and Th17 immune response in allergic airway diseases.

artículo científico publicado en 2015

IL-4 and IgE–anti-IgE modulation of 15(S)-hydroxyeicosatetraenoic acid release by mononuclear phagocytes

scientific article published on 01 January 1999

Il-4-induced lipid mediators class switching in human normal mononuclear phagocytes

scientific article published on 01 January 2003

In vitro pharmacological evaluation of multitarget agents for thromboxane prostanoid receptor antagonism and COX-2 inhibition.

artículo científico publicado en 2015

Increased dietary levels of α-linoleic acid inhibit mammary tumor growth and metastasis.

artículo científico publicado en 2015

Increased prostaglandin E2 concentrations and cyclooxygenase-2 expression in asthmatic subjects with sputum eosinophilia

artículo científico publicado en 2003

Inhaled PGE2 prevents aspirin-induced bronchoconstriction and urinary LTE4 excretion in aspirin-sensitive asthma

artículo científico publicado en 1996

Inhibition by lipoxygenase products of TXA2-like responses of platelets and vascular smooth muscle. 14-Hydroxy from 22:6n-3 is more potent than 12-HETE

artículo científico publicado en 1988

Inhibition of leukocyte leukotriene B4 production by an olive oil-derived phenol identified by mass-spectrometry

scientific article published on 01 August 1997

Inhibition of prostanoid synthesis protects against neuronal damage induced by focal ischemia in rat brain

artículo científico publicado en 1998

Isoprostanes and oxidative stress in off-pump and on-pump coronary bypass surgery

artículo científico publicado en 2006

LTC4 in normal urine

scientific article published on 01 August 1995

Leukotriene A4, and not leukotriene B4, is the main 5-lipoxygenase metabolite released by bovine leukocytes

scientific article published on 01 June 1996

Leukotriene B4 production in human mononuclear phagocytes is modulated by interleukin-4-induced 15-lipoxygenase

artículo científico publicado en 2002

Leukotriene E4 elimination and metabolism in normal human subjects

artículo científico publicado en 1990

Leukotrienes in cardiovascular diseases

artículo científico publicado en 2000

Leukotrienes: lipid bioeffectors of inflammatory reactions

artículo científico publicado en 1998

Lipid peroxidation and 5-lipoxygenase activity in chronic obstructive pulmonary disease

artículo científico publicado en 2004

Mediator release after endobronchial antigen challenge in patients with respiratory allergy

artículo científico publicado en 1990

Mediators and allergic inflammation of human airways

artículo científico publicado en 1988

Metabolism of radioisotopic variants of LTE4 in human subjects and excretion of urinary metabolites

artículo científico publicado en 1991

Monitoring inflammation and airway remodeling by fluorescence molecular tomography in a chronic asthma model.

artículo científico publicado en 2015

Monoclonal anti-CD18 antibody prevents transcellular biosynthesis of cysteinyl leukotrienes in vitro and in vivo and protects against leukotriene-dependent increase in coronary vascular resistance and myocardial stiffness.

artículo científico publicado en 2000

Morphological and functional changes of coronary vasculature caused by transcellular biosynthesis of sulfidopeptide leukotrienes in isolated heart of rabbit

scientific article published on 01 March 1996

Muscarinic receptors, leukotriene B4 production and neutrophilic inflammation in COPD patients

artículo científico publicado en 2005

Myocardial protection by the leukotriene synthesis inhibitor BAY X1005: importance of transcellular biosynthesis of cysteinyl-leukotrienes

scientific article published on 01 January 1996

Nasal neutrophilia and release of myeloperoxidase induced by nasal challenge with platelet activating factor: different degrees of responsiveness in atopic and nonatopic subjects

scientific article published on 01 April 1996

Negative ion tandem mass spectrometry of leukotriene E4, and LTE 4, metabolites: Identification of LTE 4, in human urine

scientific article published on 01 August 1991

Neutrophils, endothelial cells, and cysteinyl leukotrienes: a new approach to neutrophil-dependent inflammation?

artículo científico publicado en 2001

Nitric oxide modulation of transcellular biosynthesis of cys-leukotrienes in rabbit leukocyte-perfused heart

artículo científico publicado en 1997

Olive oils rich in natural catecholic phenols decrease isoprostane excretion in humans

scientific article published on 01 November 2000

Olive phenol hydroxytyrosol prevents passive smoking-induced oxidative stress.

artículo científico publicado en 2000

On the mechanism of aspirin asthma

PGD2 induces pulmonary hyperresponsiveness to acetylcholine in vivo in the guinea-pig

artículo científico publicado en 1987

Pharmacological characterization of 2NTX-99 [4-methoxy-N1-(4-trans-nitrooxycyclohexyl)-N3-(3-pyridinylmethyl)-1,3-benzenedicarboxamide], a potential antiatherothrombotic agent with antithromboxane and nitric oxide donor activity in platelet and vasc

artículo científico publicado en 2006

Pharmacological modulation of human platelet leukotriene C4-synthase

artículo científico publicado en 1997

Proanthocyanidins from Vitis vinifera inhibit oxidative stress-induced vascular impairment in pulmonary arteries from diabetic rats.

artículo científico publicado en 2016

Properties of LTA4 synthase in human neutrophil preparations

scientific article published on 01 January 1995

Prostaglandin E₂ possesses different potencies in inducing Vascular Endothelial Growth Factor and Interleukin-8 production in COPD human lung fibroblasts

artículo científico publicado en 2016

Prostaglandins and gastric mucosal protection by esaprazole in rats

artículo científico publicado en 1990

Quantitation of sulfidopeptide leukotrienes in biological fluids by gas chromatography-mass spectrometry

artículo científico publicado en 1990

Reduced in vivo oxidative stress following 5-methyltetrahydrofolate supplementation in patients with early-onset thrombosis and 677TT methylenetetrahydrofolate reductase genotype

artículo científico publicado en 2005

Release of leukotriene A4 versus leukotriene B4 from human polymorphonuclear leukocytes.

artículo científico publicado en 1996

Role of sodium in intracellular calcium elevation and leukotriene B4 formation by receptor-mediated activation of human neutrophils

artículo científico publicado en 2004

Stereochemical analysis and biological activity of 3-hydroxy-leukotriene B4: a metabolite from ethanol-treated rat hepatocytes

artículo científico publicado en 1994

Study of mediators of anaphylaxis in nasal wash fluids after aspirin and sodium metabisulfite nasal provocation in intolerant rhinitic patients

scientific article published on 01 November 1987

Synthesis of 19-[(2-azido-5-iodo)-benzoyloxy]-LTA4 and enzymatic conversion to the LTC4 analogue

artículo científico publicado en 2000

Synthesis of cysteinyl leukotrienes in human endothelial cells: subcellular localization and autocrine signaling through the CysLT2 receptor

artículo científico publicado en 2011

Synthesis of leukotrienes and its pharmacological control in the rabbit heart

artículo científico publicado en 1992

The Cycloxygenase-2 inhibitor SC58236 is neuroprotective in an in vivo model of focal ischemia in the rat.

artículo científico publicado en 2001

The pharmacology of leukotrienes in human airways: in vitro and in vivo studies

artículo científico publicado en 1989

The polymorphonuclear leukocyte: a cell tuned for transcellular biosynthesis of cys-leukotrienes

artículo científico publicado en 1997

The potential role of tocopherol in asthma and allergies: modification of the leukotriene pathway.

artículo científico publicado en 2001

The pulmonary pharmacology of [4-methoxy-N1-(4-trans-nitrooxycyclohexyl)-N3-(3-pyridinylmethyl)-1,3-benzenedicarboxamide] (2NTX-99), an anti-atherotrombotic compound with therapeutic potential in pathological conditions that target lung vasculature

scientific article published on 09 February 2012

Tramadol anti-inflammatory activity is not related to a direct inhibitory action on prostaglandin endoperoxide synthases

artículo científico publicado en 2000

Transcellular biosynthesis of eicosanoid lipid mediators

artículo científico publicado en 2014

Transcellular biosynthesis of eicosanoids

artículo científico publicado en 2010

Transcellular metabolism of leukotriene A4 by rabbit blood cells: lack of relevant LTC4-synthase activity in rabbit platelets

artículo científico publicado en 1997

Two-Pronged Approach to Anti-Inflammatory Therapy Through the Modulation of the Arachidonic Acid Cascade

scientific article published on 11 October 2018

Vasoconstriction to polymorphonuclear leukocytes in the isolated, perfused rabbit heart: inhibition by prostacyclin mimetics

artículo científico publicado en 1996

eNOS, COX-2, and prostacyclin production are impaired in endothelial cells from diabetics

artículo científico publicado en 2005

Lista de obras de Angelo Sala

14,15-Dehydroleukotriene A4: a specific substrate for leukotriene C4 synthase

15(S)-HETE modulates LTB(4) production and neutrophil chemotaxis in chronic bronchitis

15-Lipoxygenase expression and 15(S)-hydroxyeicoisatetraenoic acid release and reincorporation in induced sputum of asthmatic subjects

A new class of nitric oxide-releasing derivatives of cetirizine; pharmacological profile in vascular and airway smooth muscle preparations.

Activation of the orphan nuclear receptor RORalpha counteracts the proliferative effect of fatty acids on prostate cancer cells: crucial role of 5-lipoxygenase.

An improved assay for urinary LTE4

Antagonism of thromboxane receptors by diclofenac and lumiracoxib

Antiinflammatory and antioxidant effects of H2O2 generated by natural sources in Il1β-treated human endothelial cells.

Appearance of urinary metabolites of LTE4 in human subjects

Autocrine activity of cysteinyl leukotrienes in human vascular endothelial cells: Signaling through the CysLT₂ receptor

Azithromycin inhibits nuclear factor-κB activation during lung inflammation: an in vivo imaging study

Beta2 integrin-dependent neutrophil adhesion induced by minimally modified low-density lipoproteins is mainly mediated by F2-isoprostanes

Beta2-adrenergic activity modulates vascular tone regulation in lecithin:cholesterol acyltransferase knockout mice.

Bioavailability of curcumin in the rat frontal lobe and hippocampus after repeated administration of MERIVA®

Blood cell-vascular wall interactions and the production of coronary contracting sulfidopeptide leukotrienes in isolated, cell- perfused, rabbit heart

Bronchodilators modulate inflammation in chronic obstructive pulmonary disease subjects

CHF6001 I: a novel highly potent and selective phosphodiesterase 4 inhibitor with robust anti-inflammatory activity and suitable for topical pulmonary administration

CHF6001 II: a novel phosphodiesterase 4 inhibitor, suitable for topical pulmonary administration--in vivo preclinical pharmacology profile defines a potent anti-inflammatory compound with a wide therapeutic window

Chronic obstructive pulmonary disease and neutrophil infiltration: role of cigarette smoke and cyclooxygenase products

Comparative analysis of isolated human bronchi contraction and biosynthesis of cysteinyl leukotrienes using a direct 5-lipoxygenase inhibitor.

Consequences of transcellular biosynthesis of leukotriene C4 on organ function

Continuous wound infusion with chloroprocaine in a pig model of surgical lesion: drug absorption and effects on inflammatory response

Corrigendum

Corrigendum: Designing Multitarget Anti-inflammatory Agents: Chemical Modulation of the Lumiracoxib Structure toward Dual Thromboxane Antagonists-COX-2 Inhibitors

Critical role of COX-1 in prostacyclin production by human endothelial cells under modification of hydroperoxide tone

Cyclooxygenase-1 and prostacyclin production by endothelial cells in the presence of mild oxidative stress

Cyclooxygenase-2 and synthesis of PGE2 in human bronchial smooth-muscle cells

Cysteinyl leukotriene-1 receptor activation in a human bronchial epithelial cell line leads to signal transducer and activator of transcription 1-mediated eosinophil adhesion

Cysteinyl-leukotrienes and their receptors in asthma and other inflammatory diseases: critical update and emerging trends.

Cysteinyl-leukotrienes receptor activation in brain inflammatory reactions and cerebral edema formation: a role for transcellular biosynthesis of cysteinyl-leukotrienes

Designing multitarget anti-inflammatory agents: chemical modulation of the lumiracoxib structure toward dual thromboxane antagonists-COX-2 inhibitors

Differential effects of fluticasone propionate on allergen-evoked bronchoconstriction and increased urinary leukotriene E4 excretion

Differential metabolism of exogenous and endogenous arachidonic acid in human neutrophils

Direct airway injury results in elevated levels of sulfidopeptide leukotrienes, detectable in airway secretions

Dual COXIB/TP antagonists: a possible new twist in NSAID pharmacology and cardiovascular risk

Effect of endogenous and exogenous prostaglandin E(2) on interleukin-1 beta-induced cyclooxygenase-2 expression in human airway smooth-muscle cells

Effects of loratadine on cytosolic Ca2+ levels and leukotriene release: novel mechanisms of action independent of the anti-histamine activity

Effects of nedocromil sodium on bronchospasm and HS-NCA release induced by allergen inhalation in asthmatic patients

Endothelial cells as target for antiphospholipid antibodies. Human Polyclonal and Monoclonal Anti-β2-Glycoprotein I Antibodies React In Vitro with Endothelial Cells Through Adherent β2-Glycoprotein I and Induce Endothelial Activation

Eosinophil 15-lipoxygenase is a leukotriene A4 synthase.

Erratum to: Increased dietary levels of α-linolenic acid inhibit mammary tumor growth and metastasis

Estrogen Receptor-α as a Drug Target Candidate for Preventing Lung Inflammation.

Estrogen prevents the lipopolysaccharide-induced inflammatory response in microglia.

Estrogen receptor-alpha as a drug target candidate for preventing lung inflammation

Evidence of PAF-acether metabolic pathway activation in antigen challenge of upper respiratory airways.

Exhaled and non-exhaled non-invasive markers for assessment of respiratory inflammation in patients with stable COPD and healthy smokers

Formation of sulphidopeptide-leukotrienes by cell-cell interaction causes coronary vasoconstriction in isolated, cell-perfused heart of rabbit

From field to health: a simple way to increase the nutraceutical content of grape as shown by NO-dependent vascular relaxation

Furosemide attenuates bronchial responsiveness to antigen challenge "in vitro"

High urinary leukotriene E4 (LTE4) and thromboxane 2 (TXB2) levels are associated with capillary leak syndrome in bone marrow transplant patients

IL-33/ST2 axis controls Th2/IL-31 and Th17 immune response in allergic airway diseases.

IL-4 and IgE–anti-IgE modulation of 15(S)-hydroxyeicosatetraenoic acid release by mononuclear phagocytes

Il-4-induced lipid mediators class switching in human normal mononuclear phagocytes

In vitro pharmacological evaluation of multitarget agents for thromboxane prostanoid receptor antagonism and COX-2 inhibition.

Increased dietary levels of α-linoleic acid inhibit mammary tumor growth and metastasis.

Increased prostaglandin E2 concentrations and cyclooxygenase-2 expression in asthmatic subjects with sputum eosinophilia

Inhaled PGE2 prevents aspirin-induced bronchoconstriction and urinary LTE4 excretion in aspirin-sensitive asthma

Inhibition by lipoxygenase products of TXA2-like responses of platelets and vascular smooth muscle. 14-Hydroxy from 22:6n-3 is more potent than 12-HETE

Inhibition of leukocyte leukotriene B4 production by an olive oil-derived phenol identified by mass-spectrometry

Inhibition of prostanoid synthesis protects against neuronal damage induced by focal ischemia in rat brain

Isoprostanes and oxidative stress in off-pump and on-pump coronary bypass surgery

LTC4 in normal urine

Leukotriene A4, and not leukotriene B4, is the main 5-lipoxygenase metabolite released by bovine leukocytes

Leukotriene B4 production in human mononuclear phagocytes is modulated by interleukin-4-induced 15-lipoxygenase

Leukotriene E4 elimination and metabolism in normal human subjects

Leukotrienes in cardiovascular diseases

Leukotrienes: lipid bioeffectors of inflammatory reactions

Lipid peroxidation and 5-lipoxygenase activity in chronic obstructive pulmonary disease

Mediator release after endobronchial antigen challenge in patients with respiratory allergy

Mediators and allergic inflammation of human airways

Metabolism of radioisotopic variants of LTE4 in human subjects and excretion of urinary metabolites

Monitoring inflammation and airway remodeling by fluorescence molecular tomography in a chronic asthma model.

Monoclonal anti-CD18 antibody prevents transcellular biosynthesis of cysteinyl leukotrienes in vitro and in vivo and protects against leukotriene-dependent increase in coronary vascular resistance and myocardial stiffness.

Morphological and functional changes of coronary vasculature caused by transcellular biosynthesis of sulfidopeptide leukotrienes in isolated heart of rabbit

Muscarinic receptors, leukotriene B4 production and neutrophilic inflammation in COPD patients

Myocardial protection by the leukotriene synthesis inhibitor BAY X1005: importance of transcellular biosynthesis of cysteinyl-leukotrienes

Nasal neutrophilia and release of myeloperoxidase induced by nasal challenge with platelet activating factor: different degrees of responsiveness in atopic and nonatopic subjects

Negative ion tandem mass spectrometry of leukotriene E4, and LTE 4, metabolites: Identification of LTE 4, in human urine

Neutrophils, endothelial cells, and cysteinyl leukotrienes: a new approach to neutrophil-dependent inflammation?