Lista de obras - Valérie Capra - Dominio Público Uruguay

A functional G300S variant of the cysteinyl leukotriene 1 receptor is associated with atopy in a Tristan da Cunha isolate

artículo científico publicado en 2007

A role for inflammatory mediators in heterologous desensitization of CysLT1 receptor in human monocytes.

artículo científico publicado en 2009

Antagonism of thromboxane receptors by diclofenac and lumiracoxib

Autocrine activity of cysteinyl leukotrienes in human vascular endothelial cells: Signaling through the CysLT₂ receptor

artículo científico publicado en 2015

Corrigendum: Designing Multitarget Anti-inflammatory Agents: Chemical Modulation of the Lumiracoxib Structure toward Dual Thromboxane Antagonists-COX-2 Inhibitors

scholarly article by Massimo Bertinaria et al published 26 November 2012 in ChemMedChem

CysLT1 leukotriene receptor antagonists inhibit the effects of nucleotides acting at P2Y receptors

artículo científico publicado en 2005

CysLT1 receptor is a target for extracellular nucleotide-induced heterologous desensitization: a possible feedback mechanism in inflammation.

artículo científico publicado en 2005

CysLT1 receptor-induced human airway smooth muscle cells proliferation requires ROS generation, EGF receptor transactivation and ERK1/2 phosphorylation

artículo científico publicado en 2006

CysLT1 signal transduction in differentiated U937 cells involves the activation of the small GTP-binding protein Ras.

artículo científico publicado en 2004

Cysteinyl Leukotrienes Pathway Genes, Atopic Asthma and Drug Response: From Population Isolates to Large Genome-Wide Association Studies

artículo científico publicado en 2016

Cysteinyl-leukotriene receptors and cellular signals.

artículo científico publicado en 2007

Cysteinyl-leukotrienes and their receptors in asthma and other inflammatory diseases: critical update and emerging trends.

artículo científico publicado en 2007

Designing multitarget anti-inflammatory agents: chemical modulation of the lumiracoxib structure toward dual thromboxane antagonists-COX-2 inhibitors

artículo científico publicado en 2012

Dual COXIB/TP antagonists: a possible new twist in NSAID pharmacology and cardiovascular risk

artículo científico publicado en 2010

Eicosanoids and their drugs in cardiovascular diseases: focus on atherosclerosis and stroke

artículo científico publicado en 2012

Facilitation of acetylcholine signaling by the dithiocarbamate fungicide propineb.

artículo científico publicado en 2002

Full and partial agonists of thromboxane prostanoid receptor unveil fine tuning of receptor superactive conformation and G protein activation.

artículo científico publicado en 2013

Impact of vascular thromboxane prostanoid receptor activation on hemostasis, thrombosis, oxidative stress, and inflammation.

artículo científico publicado en 2014

Impaired thromboxane receptor dimerization reduces signaling efficiency: A potential mechanism for reduced platelet function in vivo.

artículo científico publicado en 2016

In vitro pharmacological evaluation of multitarget agents for thromboxane prostanoid receptor antagonism and COX-2 inhibition.

artículo científico publicado en 2015

Involvement of prenylated proteins in calcium signaling induced by LTD4 in differentiated U937 cells ⬇️

artículo científico publicado el 1 de julio de 2003

Leukotriene modifiers in the treatment of cardiovascular diseases.

artículo científico publicado en 2008

Leukotrienes and Atherosclerosis

artículo científico publicado en 2010

Leukotrienes as mediators of asthma.

artículo científico publicado en 2001

Light on the structure of thromboxane A₂receptor heterodimers.

artículo científico publicado en 2011

Molecular and functional aspects of human cysteinyl leukotriene receptors

artículo científico publicado en 2004

Mutational analysis of the highly conserved ERY motif of the thromboxane A2 receptor: alternative role in G protein-coupled receptor signaling.

artículo científico publicado en 2004

Pharmacogenetics of the G protein-coupled receptors

artículo científico publicado en 2014

Pharmacological characterization of 2NTX-99 [4-methoxy-N1-(4-trans-nitrooxycyclohexyl)-N3-(3-pyridinylmethyl)-1,3-benzenedicarboxamide], a potential antiatherothrombotic agent with antithromboxane and nitric oxide donor activity in platelet and vasc

artículo científico publicado en 2006

Pharmacological characterization of the cysteinyl-leukotriene antagonists CGP 45715A (iralukast) and CGP 57698 in human airways in vitro

artículo científico publicado en 1998

Pharmacological differences among CysLT(1) receptor antagonists with respect to LTC(4) and LTD(4) in human lung parenchyma.

artículo científico publicado en 2002

Rosuvastatin inhibits human airway smooth muscle cells mitogenic response to eicosanoid contractile agents.

artículo científico publicado en 2013

Synthesis of cysteinyl leukotrienes in human endothelial cells: subcellular localization and autocrine signaling through the CysLT2 receptor

artículo científico publicado en 2011

The DRY motif and the four corners of the cubic ternary complex model.

artículo científico publicado en 2017

The DRY motif at work: the P2Y12receptor case

scientific article published on 01 May 2014

The highly conserved DRY motif of class A G protein-coupled receptors: beyond the ground state.

artículo científico publicado en 2006

The orphan receptor GPR17 identified as a new dual uracil nucleotides/cysteinyl-leukotrienes receptor

artículo científico publicado en 2006

Thromboxane prostanoid receptor in human airway smooth muscle cells: a relevant role in proliferation.

artículo científico publicado en 2003

Thromboxane prostanoid receptor signals through Gi protein to rapidly activate extracellular signal-regulated kinase in human airways

artículo científico publicado en 2004

Transcellular biosynthesis of eicosanoid lipid mediators

artículo científico publicado en 2014

Working hypothesis on the classification of Cys-leukotriene receptors in airways.

artículo científico publicado en 1997

Lista de obras de Valérie Capra

A functional G300S variant of the cysteinyl leukotriene 1 receptor is associated with atopy in a Tristan da Cunha isolate

A role for inflammatory mediators in heterologous desensitization of CysLT1 receptor in human monocytes.

Antagonism of thromboxane receptors by diclofenac and lumiracoxib

Autocrine activity of cysteinyl leukotrienes in human vascular endothelial cells: Signaling through the CysLT₂ receptor

Corrigendum: Designing Multitarget Anti-inflammatory Agents: Chemical Modulation of the Lumiracoxib Structure toward Dual Thromboxane Antagonists-COX-2 Inhibitors

CysLT1 leukotriene receptor antagonists inhibit the effects of nucleotides acting at P2Y receptors

CysLT1 receptor is a target for extracellular nucleotide-induced heterologous desensitization: a possible feedback mechanism in inflammation.

CysLT1 receptor-induced human airway smooth muscle cells proliferation requires ROS generation, EGF receptor transactivation and ERK1/2 phosphorylation

CysLT1 signal transduction in differentiated U937 cells involves the activation of the small GTP-binding protein Ras.

Cysteinyl Leukotrienes Pathway Genes, Atopic Asthma and Drug Response: From Population Isolates to Large Genome-Wide Association Studies

Cysteinyl-leukotriene receptors and cellular signals.

Cysteinyl-leukotrienes and their receptors in asthma and other inflammatory diseases: critical update and emerging trends.

Designing multitarget anti-inflammatory agents: chemical modulation of the lumiracoxib structure toward dual thromboxane antagonists-COX-2 inhibitors

Dual COXIB/TP antagonists: a possible new twist in NSAID pharmacology and cardiovascular risk

Eicosanoids and their drugs in cardiovascular diseases: focus on atherosclerosis and stroke

Facilitation of acetylcholine signaling by the dithiocarbamate fungicide propineb.

Full and partial agonists of thromboxane prostanoid receptor unveil fine tuning of receptor superactive conformation and G protein activation.

Impact of vascular thromboxane prostanoid receptor activation on hemostasis, thrombosis, oxidative stress, and inflammation.

Impaired thromboxane receptor dimerization reduces signaling efficiency: A potential mechanism for reduced platelet function in vivo.

In vitro pharmacological evaluation of multitarget agents for thromboxane prostanoid receptor antagonism and COX-2 inhibition.

Involvement of prenylated proteins in calcium signaling induced by LTD4 in differentiated U937 cells ⬇️

Leukotriene modifiers in the treatment of cardiovascular diseases.

Leukotrienes and Atherosclerosis

Leukotrienes as mediators of asthma.

Light on the structure of thromboxane A₂receptor heterodimers.

Molecular and functional aspects of human cysteinyl leukotriene receptors

Mutational analysis of the highly conserved ERY motif of the thromboxane A2 receptor: alternative role in G protein-coupled receptor signaling.

Pharmacogenetics of the G protein-coupled receptors

Pharmacological characterization of 2NTX-99 [4-methoxy-N1-(4-trans-nitrooxycyclohexyl)-N3-(3-pyridinylmethyl)-1,3-benzenedicarboxamide], a potential antiatherothrombotic agent with antithromboxane and nitric oxide donor activity in platelet and vasc

Pharmacological characterization of the cysteinyl-leukotriene antagonists CGP 45715A (iralukast) and CGP 57698 in human airways in vitro

Pharmacological differences among CysLT(1) receptor antagonists with respect to LTC(4) and LTD(4) in human lung parenchyma.

Rosuvastatin inhibits human airway smooth muscle cells mitogenic response to eicosanoid contractile agents.

Synthesis of cysteinyl leukotrienes in human endothelial cells: subcellular localization and autocrine signaling through the CysLT2 receptor

The DRY motif and the four corners of the cubic ternary complex model.

The DRY motif at work: the P2Y12receptor case

The highly conserved DRY motif of class A G protein-coupled receptors: beyond the ground state.

The orphan receptor GPR17 identified as a new dual uracil nucleotides/cysteinyl-leukotrienes receptor

Thromboxane prostanoid receptor in human airway smooth muscle cells: a relevant role in proliferation.

Thromboxane prostanoid receptor signals through Gi protein to rapidly activate extracellular signal-regulated kinase in human airways

Transcellular biosynthesis of eicosanoid lipid mediators

Working hypothesis on the classification of Cys-leukotriene receptors in airways.