Lista de obras - Andre Boonstra - Dominio Público Uruguay

1alpha,25-Dihydroxyvitamin d3 has a direct effect on naive CD4(+) T cells to enhance the development of Th2 cells.

artículo científico publicado en 2001

A STAT4 variant increases liver fibrosis risk in Caucasian patients with chronic hepatitis B

scientific article published on 02 July 2018

A mutation in the progesterone receptor predisposes to HEV infection in HIV-positive patients

artículo científico publicado en 2017

Abundant numbers of regulatory T cells localize to the liver of chronic hepatitis C infected patients and limit the extent of fibrosis

artículo científico publicado en 2009

Alpha-galactosylceramide in chronic hepatitis B infection: results from a randomized placebo-controlled Phase I/II trial.

artículo científico publicado en 2009

Analysis of the transcriptome and immune function of monocytes during IFNα-based therapy in chronic HCV revealed induction of TLR7 responsiveness

artículo científico publicado en 2014

Assessment of the effect of ribavirin on myeloid and plasmacytoid dendritic cells during interferon-based therapy of chronic hepatitis B patients

artículo científico publicado en 2012

Association between liver fibrosis and hepatitis E seroprevalence among HIV-positive individuals in Nepal

article

Biochemical measures and frailty in people with intellectual disabilities

artículo científico publicado en 2015

CD4+ CXCR5+ T cells in chronic HCV infection produce less IL-21, yet are efficient at supporting B cell responses

artículo científico publicado en 2014

Characterization of the “a” determinant region of the hepatitis B virus genome in Iranian patients at different clinical phases of chronic infection.

artículo científico publicado en 2018

Continuous interferon-α2b infusion in combination with ribavirin for chronic hepatitis C in treatment-experienced patients

artículo científico publicado en 2011

Controversy on the role of FoxP3⁺ regulatory T cells in fibrogenesis in chronic hepatitis C virus infections

artículo científico publicado en 2013

Decreased pro-inflammatory immune responses during recurrent acute HCV infections in HIV co-infected patients

artículo científico publicado en 2017

Differential expression of innate immune response genes in clinical phases of chronic hepatitis B infection

artículo científico publicado en 2017

Differential ultraviolet-B-induced immunomodulation in XPA, XPC, and CSB DNA repair-deficient mice

artículo científico publicado en 2001

Early morbidity encountered in the dietary-related mouse model of Barrett's esophagus: a question of zinc?

artículo científico publicado en 2010

Endogenous IFNλ in viral hepatitis patients

artículo científico publicado en 2014

Enhanced protection to Mycobacterium tuberculosis infection in IL-10-deficient mice is accompanied by early and enhanced Th1 responses in the lung

artículo científico publicado en 2010

Erythropoietin administration suppresses human monocyte function in vitro and during therapy-induced anemia in HCV patients

artículo científico publicado en 2013

Evaluation of IL-28B polymorphisms and serum IP-10 in hepatitis C infected chimpanzees

artículo científico publicado en 2012

Flexibility of mouse classical and plasmacytoid-derived dendritic cells in directing T helper type 1 and 2 cell development: dependency on antigen dose and differential toll-like receptor ligation ⬇️

artículo científico publicado en 2003

Focus on the liver: Host-virus interactions in HBV.

artículo científico publicado en 2017

Follicular T helper cells and humoral reactivity in kidney transplant patients

artículo científico publicado en 2015

Frequencies of Circulating MAIT Cells Are Diminished in Chronic HCV, HIV and HCV/HIV Co-Infection and Do Not Recover during Therapy

artículo científico publicado en 2016

Gene expression profiling of human tissue-resident immune cells: Comparing blood and liver

article

Gene expression profiling to predict and assess the consequences of therapy-induced virus eradication in chronic hepatitis C virus infection

artículo científico publicado en 2014

Hepatitis B core-related antigen levels are associated with response to entecavir and peginterferon add-on therapy in hepatitis B e antigen-positive chronic hepatitis B patients

artículo científico publicado en 2016

Hepatitis B core-related antigen levels predict recurrence-free survival in patients with HBV-associated early-stage hepatocellular carcinoma: results from a Dutch long-term follow-up study

artículo científico publicado en 2020

Hepatitis B core-related antigen monitoring during peginterferon alfa treatment for HBeAg-negative chronic hepatitis B

artículo científico publicado en 2019

Hepatitis B virus infection and the immune response: The big questions

artículo científico publicado en 2017

Hepatitis C treatment and liver cancer recurrence: cause for concern?

artículo científico publicado en 2017

Hepatitis E Virus (HEV) Genotype 3 Infection of Human Liver Chimeric Mice as a Model for Chronic HEV Infection

artículo científico publicado en 2016

Host and viral factors associated with serum hepatitis B virus RNA levels among patients in need for treatment.

artículo científico publicado en 2018

IFN-λ is able to augment TLR-mediated activation and subsequent function of primary human B cells

artículo científico publicado en 2015

IFN-λ-mediated IL-12 production in macrophages induces IFN-γ production in human NK cells

artículo científico publicado en 2014

IL-10-secreting regulatory T cells do not express Foxp3 but have comparable regulatory function to naturally occurring CD4+CD25+ regulatory T cells

artículo científico publicado en 2004

IL-29 and IFNα differ in their ability to modulate IL-12 production by TLR-activated human macrophages and exhibit differential regulation of the IFNγ receptor expression

artículo científico publicado en 2010

ITPA Polymorphisms Are Associated with Hematological Side Effects during Antiviral Therapy for Chronic HCV Infection

artículo científico publicado en 2015

Immune activation in prolonged cART-suppressed HIV patients is comparable to that of healthy controls.

artículo científico publicado en 2017

Immune mechanisms of vaccine induced protection against chronic hepatitis C virus infection in chimpanzees.

artículo científico publicado en 2015

Immunological Analysis During Interferon-Free Therapy for Chronic Hepatitis C Virus Infection Reveals Modulation of the Natural Killer Cell Compartment

artículo científico publicado en 2015

Immunological biomarker discovery in cure regimens for chronic hepatitis B virus infection

artículo científico publicado en 2022

Immunology of hepatitis B and hepatitis C virus infections.

artículo científico publicado en 2008

Immunology of hepatitis C virus infections.

artículo científico

In vitro generation of interleukin 10-producing regulatory CD4(+) T cells is induced by immunosuppressive drugs and inhibited by T helper type 1 (Th1)- and Th2-inducing cytokines.

artículo científico publicado en 2002

Inflammatory monocytes recruited to the liver within 24 hours after virus-induced inflammation resemble Kupffer cells but are functionally distinct

artículo científico publicado en 2015

Inhibitory receptor molecules in chronic hepatitis B and C infections: novel targets for immunotherapy?

artículo científico publicado en 2014

Interferon-alpha treatment rapidly clears Hepatitis E virus infection in humanized mice

artículo científico publicado en 2017

Intrahepatic natural killer cell activation, but not function, is associated with HBsAg levels in patients with HBeAg-negative chronic hepatitis B.

artículo científico publicado en 2013

Intrahepatic regulatory T cells are phenotypically distinct from their peripheral counterparts in chronic HBV patients.

artículo científico publicado en 2008

Kupffer cells express a unique combination of phenotypic and functional characteristics compared with splenic and peritoneal macrophages.

artículo científico publicado en 2012

Kupffer cells interact with hepatitis B surface antigen in vivo and in vitro, leading to proinflammatory cytokine production and natural killer cell function.

artículo científico publicado en 2014

Levels of Cytokines in Serum Associate With Development of Hepatocellular Carcinoma in Patients With HCV Infection Treated With Direct-acting Antivirals.

artículo científico publicado en 2017

Liver Monocytes and Kupffer Cells Remain Transcriptionally Distinct during Chronic Viral Infection

artículo científico publicado en 2016

Longitudinal analysis of peripheral and intrahepatic NK cells in chronic HCV patients during antiviral therapy.

artículo científico publicado en 2015

Macrophages and myeloid dendritic cells, but not plasmacytoid dendritic cells, produce IL-10 in response to MyD88- and TRIF-dependent TLR signals, and TLR-independent signals.

artículo científico publicado en 2006

Malaria infection changes the ability of splenic dendritic cell populations to stimulate antigen-specific T cells

artículo científico publicado en 2006

Mechanisms of Accelerated Liver Fibrosis Progression during HIV Infection.

artículo científico publicado en 2016

Metabolic characterization of the natural progression of chronic hepatitis B.

artículo científico publicado en 2016

Modulation of Toll-like receptor 9 expression on monocytes of viral hepatitis patients.

artículo científico publicado en 2014

Modulation of dendritic cell function by persistent viruses.

artículo científico publicado en 2008

Monocytes from chronic HBV patients react in vitro to HBsAg and TLR by producing cytokines irrespective of stage of disease

artículo científico publicado en 2014

Mouse type I IFN-producing cells are immature APCs with plasmacytoid morphology

article by Carine Asselin-Paturel et al published 19 November 2001 in Nature Immunology

Mucosal-associated invariant T (MAIT) cells are more activated in chronic hepatitis B, but not depleted in blood: reversal by antiviral therapy

artículo científico publicado en 2017

Mucosal-associated invariant T-cell frequency and function in blood and liver of HCV mono- and HCV/HIV co-infected patients with advanced fibrosis.

artículo científico publicado en 2017

NK cell phenotypic and functional shifts coincide with specific clinical phases in the natural history of chronic HBV infection

artículo científico publicado en 2017

NK cells in self-limited HCV infection exhibit a more extensively differentiated, but not memory-like, repertoire.

artículo científico publicado en 2017

Natural killer cell activity and function in chronic HCV-infected patients during peg interferon and ribavirin: early effects of active substance use.

artículo científico publicado en 2013

Negative regulation of hepatitis C virus specific immunity is highly heterogeneous and modulated by pegylated interferon-alpha/ribavirin therapy

artículo científico publicado en 2012

PI3K-PKB hyperactivation augments human plasmacytoid dendritic cell development and function.

artículo científico publicado en 2012

Persistent metabolic changes in HIV-infected patients during the first year of combination antiretroviral therapy

scientific article published in Scientific Reports

Polymorphisms of HLA-DP are associated with response to peginterferon in Caucasian patients with chronic hepatitis B.

artículo científico publicado en 2014

Potent immune activation in chronic hepatitis C patients upon administration of an oral inducer of endogenous interferons that acts via Toll-like receptor 7

article

Precore and core promoter mutants are associated with higher HBeAg seroconversion but low disease remission rates in HBV patients treated with nucleos(t)ide analogues

scientific article published on 05 December 2012

Prediction of long-term clinical outcome in a diverse chronic hepatitis B population: Role of the PAGE-B score.

artículo científico publicado en 2017

Prevalence and risk of hepatitis E virus infection in the HIV population of Nepal

artículo científico publicado en 2017

Randomised clinical trial: anti-viral activity of ANA773, an oral inducer of endogenous interferons acting via TLR7, in chronic HCV.

artículo científico publicado en 2011

Re-evaluation of hepatitis B virus clinical phases by systems biology identifies unappreciated roles for the innate immune response and B cells

artículo científico publicado en 2015

Relationship between hepatitis B core-related antigen levels and sustained HBeAg seroconversion in patients treated with nucleo(s)tide analogues

artículo científico publicado en 2019

Restoration of TLR3-activated myeloid dendritic cell activity leads to improved natural killer cell function in chronic hepatitis B virus infection

artículo científico publicado en 2012

Retention of CD4+ CD25+ FoxP3+ regulatory T cells in the liver after therapy-induced hepatitis C virus eradication in humans

artículo científico publicado en 2011

Role for IL-10 in inducing functional impairment of monocytes upon TLR4 ligation in patients with chronic HCV infections

artículo científico publicado en 2011

Role of T cell immunity in hepatitis C virus infections.

artículo científico publicado en 2013

Role of microbial translocation in soluble CD14 up-regulation in HIV-, but not in HCV-, infected chimpanzees

artículo científico publicado en 2016

Sensitive detection of hepatocellular injury in chronic hepatitis C patients with circulating hepatocyte-derived microRNA-122.

artículo científico publicado en 2012

Serum hepatitis B virus RNA predicts response to peginterferon treatment in HBeAg-positive chronic hepatitis B

artículo científico publicado en 2020

Serum levels of interferon-gamma-inducible protein 10 and response to peginterferon therapy in HBeAg-positive chronic hepatitis B.

artículo científico publicado en 2013

Similar frequencies, phenotype and activation status of intrahepatic NK cells in chronic HBV patients after long-term treatment with tenofovir disoproxil fumarate (TDF).

artículo científico publicado en 2016

Spontaneous and natural cytotoxicity receptor-mediated cytotoxicity are effector functions of distinct natural killer subsets in hepatitis C virus-infected chimpanzees

artículo científico publicado en 2016

Sustained virologic response after therapy with the HCV protease inhibitor narlaprevir in combination with peginterferon and ribavirin is durable through long-term follow-up.

artículo científico publicado en 2013

T-cell responses at baseline and during therapy with peginterferon-alpha and ribavirin are not associated with outcome in chronic hepatitis C infected patients.

artículo científico publicado en 2010

TLR7 polymorphism, sex and chronic HBV infection influence plasmacytoid DC maturation by TLR7 ligands

artículo científico publicado en 2018

The DNA-binding factor Ctcf critically controls gene expression in macrophages.

artículo científico publicado en 2013

The Intrahepatic T Cell Compartment Does Not Normalize Years After Therapy-Induced Hepatitis C Virus Eradication

artículo científico publicado en 2015

The Path to Cancer and Back: Immune Modulation During Hepatitis C Virus Infection, Progression to Fibrosis and Cancer, and Unexpected Roles of New Antivirals.

artículo científico publicado en 2016

The development of murine plasmacytoid dendritic cell precursors is differentially regulated by FLT3-ligand and granulocyte/macrophage colony-stimulating factor

artículo científico publicado en 2002

The impact of PNPLA3 (rs738409 C>G) polymorphisms on liver histology and long-term clinical outcome in chronic hepatitis B patients

artículo científico publicado en 2014

The membrane-bound O-acyltransferase domain-containing 7 variant rs641738 increases inflammation and fibrosis in chronic hepatitis B.

artículo científico publicado en 2017

The response to TLR ligation of human CD16⁺CD14⁻ monocytes is weakly modulated as a consequence of persistent infection with the hepatitis C virus

artículo científico publicado en 2011

The role of Kupffer cells in hepatitis B and hepatitis C virus infections.

artículo científico

The role of cytokines in ultraviolet-B induced immunosuppression.

artículo científico publicado en 1997

Type I and III interferons enhance IL-10R expression on human monocytes and macrophages, resulting in IL-10-mediated suppression of TLR-induced IL-12

artículo científico publicado en 2012

Type I interferon dependence of plasmacytoid dendritic cell activation and migration.

artículo científico publicado en 2005

UV exposure alters respiratory allergic responses in mice

artículo científico publicado en 2000

UVB irradiation modulates systemic immune responses by affecting cytokine production of antigen-presenting cells

scientific article published on 01 November 2000

Understanding IFNλ in rheumatoid arthritis.

artículo científico publicado en 2014

Unique intrahepatic transcriptomics profiles discriminate the clinical phases of a chronic HBV infection.

artículo científico publicado en 2017

Lista de obras de Andre Boonstra

1alpha,25-Dihydroxyvitamin d3 has a direct effect on naive CD4(+) T cells to enhance the development of Th2 cells.

A STAT4 variant increases liver fibrosis risk in Caucasian patients with chronic hepatitis B

A mutation in the progesterone receptor predisposes to HEV infection in HIV-positive patients

Abundant numbers of regulatory T cells localize to the liver of chronic hepatitis C infected patients and limit the extent of fibrosis

Alpha-galactosylceramide in chronic hepatitis B infection: results from a randomized placebo-controlled Phase I/II trial.

Analysis of the transcriptome and immune function of monocytes during IFNα-based therapy in chronic HCV revealed induction of TLR7 responsiveness

Assessment of the effect of ribavirin on myeloid and plasmacytoid dendritic cells during interferon-based therapy of chronic hepatitis B patients

Association between liver fibrosis and hepatitis E seroprevalence among HIV-positive individuals in Nepal

Biochemical measures and frailty in people with intellectual disabilities

CD4+ CXCR5+ T cells in chronic HCV infection produce less IL-21, yet are efficient at supporting B cell responses

Characterization of the “a” determinant region of the hepatitis B virus genome in Iranian patients at different clinical phases of chronic infection.

Continuous interferon-α2b infusion in combination with ribavirin for chronic hepatitis C in treatment-experienced patients

Controversy on the role of FoxP3⁺ regulatory T cells in fibrogenesis in chronic hepatitis C virus infections

Decreased pro-inflammatory immune responses during recurrent acute HCV infections in HIV co-infected patients

Differential expression of innate immune response genes in clinical phases of chronic hepatitis B infection

Differential ultraviolet-B-induced immunomodulation in XPA, XPC, and CSB DNA repair-deficient mice

Early morbidity encountered in the dietary-related mouse model of Barrett's esophagus: a question of zinc?

Endogenous IFNλ in viral hepatitis patients

Enhanced protection to Mycobacterium tuberculosis infection in IL-10-deficient mice is accompanied by early and enhanced Th1 responses in the lung

Erythropoietin administration suppresses human monocyte function in vitro and during therapy-induced anemia in HCV patients

Evaluation of IL-28B polymorphisms and serum IP-10 in hepatitis C infected chimpanzees

Flexibility of mouse classical and plasmacytoid-derived dendritic cells in directing T helper type 1 and 2 cell development: dependency on antigen dose and differential toll-like receptor ligation ⬇️

Focus on the liver: Host-virus interactions in HBV.

Follicular T helper cells and humoral reactivity in kidney transplant patients

Frequencies of Circulating MAIT Cells Are Diminished in Chronic HCV, HIV and HCV/HIV Co-Infection and Do Not Recover during Therapy

Gene expression profiling of human tissue-resident immune cells: Comparing blood and liver

Gene expression profiling to predict and assess the consequences of therapy-induced virus eradication in chronic hepatitis C virus infection

Hepatitis B core-related antigen levels are associated with response to entecavir and peginterferon add-on therapy in hepatitis B e antigen-positive chronic hepatitis B patients

Hepatitis B core-related antigen levels predict recurrence-free survival in patients with HBV-associated early-stage hepatocellular carcinoma: results from a Dutch long-term follow-up study

Hepatitis B core-related antigen monitoring during peginterferon alfa treatment for HBeAg-negative chronic hepatitis B

Hepatitis B virus infection and the immune response: The big questions

Hepatitis C treatment and liver cancer recurrence: cause for concern?

Hepatitis E Virus (HEV) Genotype 3 Infection of Human Liver Chimeric Mice as a Model for Chronic HEV Infection

Host and viral factors associated with serum hepatitis B virus RNA levels among patients in need for treatment.

IFN-λ is able to augment TLR-mediated activation and subsequent function of primary human B cells

IFN-λ-mediated IL-12 production in macrophages induces IFN-γ production in human NK cells

IL-10-secreting regulatory T cells do not express Foxp3 but have comparable regulatory function to naturally occurring CD4+CD25+ regulatory T cells

IL-29 and IFNα differ in their ability to modulate IL-12 production by TLR-activated human macrophages and exhibit differential regulation of the IFNγ receptor expression

ITPA Polymorphisms Are Associated with Hematological Side Effects during Antiviral Therapy for Chronic HCV Infection

Immune activation in prolonged cART-suppressed HIV patients is comparable to that of healthy controls.

Immune mechanisms of vaccine induced protection against chronic hepatitis C virus infection in chimpanzees.

Immunological Analysis During Interferon-Free Therapy for Chronic Hepatitis C Virus Infection Reveals Modulation of the Natural Killer Cell Compartment

Immunological biomarker discovery in cure regimens for chronic hepatitis B virus infection

Immunology of hepatitis B and hepatitis C virus infections.

Immunology of hepatitis C virus infections.

In vitro generation of interleukin 10-producing regulatory CD4(+) T cells is induced by immunosuppressive drugs and inhibited by T helper type 1 (Th1)- and Th2-inducing cytokines.

Inflammatory monocytes recruited to the liver within 24 hours after virus-induced inflammation resemble Kupffer cells but are functionally distinct

Inhibitory receptor molecules in chronic hepatitis B and C infections: novel targets for immunotherapy?

Interferon-alpha treatment rapidly clears Hepatitis E virus infection in humanized mice

Intrahepatic natural killer cell activation, but not function, is associated with HBsAg levels in patients with HBeAg-negative chronic hepatitis B.

Intrahepatic regulatory T cells are phenotypically distinct from their peripheral counterparts in chronic HBV patients.

Kupffer cells express a unique combination of phenotypic and functional characteristics compared with splenic and peritoneal macrophages.

Kupffer cells interact with hepatitis B surface antigen in vivo and in vitro, leading to proinflammatory cytokine production and natural killer cell function.

Levels of Cytokines in Serum Associate With Development of Hepatocellular Carcinoma in Patients With HCV Infection Treated With Direct-acting Antivirals.

Liver Monocytes and Kupffer Cells Remain Transcriptionally Distinct during Chronic Viral Infection

Longitudinal analysis of peripheral and intrahepatic NK cells in chronic HCV patients during antiviral therapy.

Macrophages and myeloid dendritic cells, but not plasmacytoid dendritic cells, produce IL-10 in response to MyD88- and TRIF-dependent TLR signals, and TLR-independent signals.

Malaria infection changes the ability of splenic dendritic cell populations to stimulate antigen-specific T cells

Mechanisms of Accelerated Liver Fibrosis Progression during HIV Infection.

Metabolic characterization of the natural progression of chronic hepatitis B.

Modulation of Toll-like receptor 9 expression on monocytes of viral hepatitis patients.

Modulation of dendritic cell function by persistent viruses.

Monocytes from chronic HBV patients react in vitro to HBsAg and TLR by producing cytokines irrespective of stage of disease

Mouse type I IFN-producing cells are immature APCs with plasmacytoid morphology

Mucosal-associated invariant T (MAIT) cells are more activated in chronic hepatitis B, but not depleted in blood: reversal by antiviral therapy

Mucosal-associated invariant T-cell frequency and function in blood and liver of HCV mono- and HCV/HIV co-infected patients with advanced fibrosis.

NK cell phenotypic and functional shifts coincide with specific clinical phases in the natural history of chronic HBV infection

NK cells in self-limited HCV infection exhibit a more extensively differentiated, but not memory-like, repertoire.

Natural killer cell activity and function in chronic HCV-infected patients during peg interferon and ribavirin: early effects of active substance use.

Negative regulation of hepatitis C virus specific immunity is highly heterogeneous and modulated by pegylated interferon-alpha/ribavirin therapy

PI3K-PKB hyperactivation augments human plasmacytoid dendritic cell development and function.

Persistent metabolic changes in HIV-infected patients during the first year of combination antiretroviral therapy

Polymorphisms of HLA-DP are associated with response to peginterferon in Caucasian patients with chronic hepatitis B.

Potent immune activation in chronic hepatitis C patients upon administration of an oral inducer of endogenous interferons that acts via Toll-like receptor 7

Precore and core promoter mutants are associated with higher HBeAg seroconversion but low disease remission rates in HBV patients treated with nucleos(t)ide analogues

Prediction of long-term clinical outcome in a diverse chronic hepatitis B population: Role of the PAGE-B score.

Prevalence and risk of hepatitis E virus infection in the HIV population of Nepal

Randomised clinical trial: anti-viral activity of ANA773, an oral inducer of endogenous interferons acting via TLR7, in chronic HCV.

Re-evaluation of hepatitis B virus clinical phases by systems biology identifies unappreciated roles for the innate immune response and B cells