Lista de obras - Christiaan Klijn - Dominio Público Uruguay

A Clinically Applicable Gene-Expression Classifier Reveals Intrinsic and Extrinsic Contributions to Consensus Molecular Subtypes in Primary and Metastatic Colon Cancer

artículo científico publicado en 2019

A comprehensive transcriptional portrait of human cancer cell lines

artículo científico publicado en 2014

A high-throughput functional complementation assay for classification of BRCA1 missense variants

artículo científico publicado en 2013

A preclinical mouse model of invasive lobular breast cancer metastasis

artículo científico publicado en 2012

A resource for cell line authentication, annotation and quality control

artículo científico publicado en 2015

Analysis of tumor heterogeneity and cancer gene networks using deep sequencing of MMTV-induced mouse mammary tumors.

artículo científico publicado en 2013

BRCA1 RING function is essential for tumor suppression but dispensable for therapy resistance.

artículo científico publicado en 2011

BRCA1185delAG tumors may acquire therapy resistance through expression of RING-less BRCA1

artículo científico publicado en 2016

Cross-species comparison of aCGH data from mouse and human BRCA1- and BRCA2-mutated breast cancers

artículo científico publicado en 2010

ERBB3 and IGF1R Signaling Are Required for Nrf2-Dependent Growth in KEAP1-Mutant Lung Cancer

artículo científico publicado en 2019

Genome and transcriptome sequencing of lung cancers reveal diverse mutational and splicing events.

artículo científico publicado en 2012

High-throughput semiquantitative analysis of insertional mutations in heterogeneous tumors.

artículo científico publicado en 2011

Highlights from the 6th International Society for Computational Biology Student Council Symposium at the 18th Annual International Conference on Intelligent Systems for Molecular Biology.

artículo científico publicado en 2010

Identification of cancer genes using a statistical framework for multiexperiment analysis of nondiscretized array CGH data

artículo científico publicado en 2008

Identification of networks of co-occurring, tumor-related DNA copy number changes using a genome-wide scoring approach

artículo científico publicado en 2010

Insertional mutagenesis identifies drivers of a novel oncogenic pathway in invasive lobular breast carcinoma

artículo científico publicado en 2017

Integrated exome and transcriptome sequencing reveals ZAK isoform usage in gastric cancer

artículo científico publicado en 2014

Integration of DNA copy number alterations and prognostic gene expression signatures in breast cancer patients

artículo científico publicado en 2010

KC-SMARTR: An R package for detection of statistically significant aberrations in multi-experiment aCGH data.

artículo científico publicado en 2010

Lack of genomic heterogeneity at high-resolution aCGH between primary breast cancers and their paired lymph node metastases

artículo científico publicado en 2014

Loss of p53 partially rescues embryonic development of Palb2 knockout mice but does not foster haploinsufficiency of Palb2 in tumour suppression

scientific journal article

Module-based outcome prediction using breast cancer compendia

artículo científico publicado en 2007

Palb2 synergizes with Trp53 to suppress mammary tumor formation in a model of inherited breast cancer

scientific journal article

Pharmacological Induction of RAS-GTP Confers RAF Inhibitor Sensitivity in KRAS Mutant Tumors

artículo científico publicado en 2018

Ras-MEK Signaling Mediates a Critical Chk1-Dependent DNA Damage Response in Cancer Cells

artículo científico publicado en 2017

Recurrent Loss of NFE2L2 Exon 2 Is a Mechanism for Nrf2 Pathway Activation in Human Cancers

artículo científico publicado en 2016

SUV420H2 is an epigenetic regulator of epithelial/mesenchymal states in pancreatic cancer

artículo científico publicado en 2017

Somatic structural rearrangements in genetically engineered mouse mammary tumors

artículo científico publicado en 2010

Specific genomic aberrations in primary colorectal cancer are associated with liver metastases

artículo científico publicado en 2010

The Hippo pathway effector TAZ induces TEAD-dependent liver inflammation and tumors

scientific article published on 11 September 2018

Tissue-Specific Mutations in BRAF and EGFR Necessitate Unique Therapeutic Approaches.

artículo científico publicado en 2016

Lista de obras de Christiaan Klijn

A Clinically Applicable Gene-Expression Classifier Reveals Intrinsic and Extrinsic Contributions to Consensus Molecular Subtypes in Primary and Metastatic Colon Cancer

A comprehensive transcriptional portrait of human cancer cell lines

A high-throughput functional complementation assay for classification of BRCA1 missense variants

A preclinical mouse model of invasive lobular breast cancer metastasis

A resource for cell line authentication, annotation and quality control

Analysis of tumor heterogeneity and cancer gene networks using deep sequencing of MMTV-induced mouse mammary tumors.

BRCA1 RING function is essential for tumor suppression but dispensable for therapy resistance.

BRCA1185delAG tumors may acquire therapy resistance through expression of RING-less BRCA1

Cross-species comparison of aCGH data from mouse and human BRCA1- and BRCA2-mutated breast cancers

ERBB3 and IGF1R Signaling Are Required for Nrf2-Dependent Growth in KEAP1-Mutant Lung Cancer

Genome and transcriptome sequencing of lung cancers reveal diverse mutational and splicing events.

High-throughput semiquantitative analysis of insertional mutations in heterogeneous tumors.

Highlights from the 6th International Society for Computational Biology Student Council Symposium at the 18th Annual International Conference on Intelligent Systems for Molecular Biology.

Identification of cancer genes using a statistical framework for multiexperiment analysis of nondiscretized array CGH data

Identification of networks of co-occurring, tumor-related DNA copy number changes using a genome-wide scoring approach

Insertional mutagenesis identifies drivers of a novel oncogenic pathway in invasive lobular breast carcinoma

Integrated exome and transcriptome sequencing reveals ZAK isoform usage in gastric cancer

Integration of DNA copy number alterations and prognostic gene expression signatures in breast cancer patients

KC-SMARTR: An R package for detection of statistically significant aberrations in multi-experiment aCGH data.

Lack of genomic heterogeneity at high-resolution aCGH between primary breast cancers and their paired lymph node metastases

Loss of p53 partially rescues embryonic development of Palb2 knockout mice but does not foster haploinsufficiency of Palb2 in tumour suppression

Module-based outcome prediction using breast cancer compendia

Palb2 synergizes with Trp53 to suppress mammary tumor formation in a model of inherited breast cancer

Pharmacological Induction of RAS-GTP Confers RAF Inhibitor Sensitivity in KRAS Mutant Tumors

Ras-MEK Signaling Mediates a Critical Chk1-Dependent DNA Damage Response in Cancer Cells

Recurrent Loss of NFE2L2 Exon 2 Is a Mechanism for Nrf2 Pathway Activation in Human Cancers

SUV420H2 is an epigenetic regulator of epithelial/mesenchymal states in pancreatic cancer

Somatic structural rearrangements in genetically engineered mouse mammary tumors

Specific genomic aberrations in primary colorectal cancer are associated with liver metastases

The Hippo pathway effector TAZ induces TEAD-dependent liver inflammation and tumors

Tissue-Specific Mutations in BRAF and EGFR Necessitate Unique Therapeutic Approaches.