Lista de obras - Samuel Singer - Dominio Público Uruguay

13C- and 31P-NMR studies of human colon cancer in-vitro and in-vivo

artículo científico publicado en 1993

A Phase Ib/II Study of Gemcitabine and Docetaxel in Combination With Pazopanib for the Neoadjuvant Treatment of Soft Tissue Sarcomas

artículo científico publicado en 2015

A developmental model of sarcomagenesis defines a differentiation-based classification for liposarcomas.

artículo científico publicado en 2008

A differentiation-based phylogeny of cancer subtypes

artículo científico publicado en 2010

A recurrent neomorphic mutation in MYOD1 defines a clinically aggressive subset of embryonal rhabdomyosarcoma associated with PI3K-AKT pathway mutations

artículo científico publicado en 2014

A tribute to Murray F. Brennan, MD.

artículo científico publicado en 2008

Acquired resistance to imatinib in gastrointestinal stromal tumor occurs through secondary gene mutation

artículo científico publicado en 2005

Activity of Sorafenib against desmoid tumor/deep fibromatosis

artículo científico publicado en 2011

Adult rhabdomyosarcoma survival improved with treatment on multimodality protocols.

artículo científico publicado en 2013

Adults with Ewing's sarcoma/primitive neuroectodermal tumor: adverse effect of older age and primary extraosseous disease on outcome

artículo científico publicado en 1999

Advanced well-differentiated/dedifferentiated liposarcomas: role of chemotherapy and survival

artículo científico publicado en 2011

Advances in sarcoma genomics and new therapeutic targets

artículo científico publicado en 2011

An Empirical Evaluation of normalization Methods for MicroRNA Arrays in a Liposarcoma Study ⬇️

artículo científico publicado el 18 de marzo de 2013

Angiogenic profile of soft tissue sarcomas based on analysis of circulating factors and microarray gene expression.

artículo científico publicado en 2006

Atypical lipomatous tumor/well-differentiated liposarcoma of the extremity and trunk wall: importance of histological subtype with treatment recommendations.

artículo científico publicado en 2004

Biochemical analysis using high-resolution magic angle spinning NMR spectroscopy distinguishes lipoma-like well-differentiated liposarcoma from normal fat.

artículo científico publicado en 2001

Blood neutrophil-to-lymphocyte ratio is prognostic in gastrointestinal stromal tumor.

artículo científico publicado en 2012

Circulating angiogenic factor levels correlate with extent of disease and risk of recurrence in patients with soft tissue sarcoma

artículo científico publicado en 2004

Clinical and molecular approaches to well differentiated and dedifferentiated liposarcoma.

artículo científico publicado en 2011

Comparison of Perioperative Radiation Therapy and Surgery Versus Surgery Alone in 204 Patients With Primary Retroperitoneal Sarcoma: A Retrospective 2-Institution Study

artículo científico publicado en 2015

Comparison of local recurrence with conventional and intensity-modulated radiation therapy for primary soft-tissue sarcomas of the extremity

artículo científico publicado en 2014

Consistent MYC and FLT4 gene amplification in radiation‐induced angiosarcoma but not in other radiation‐associated atypical vascular lesions ⬇️

artículo científico publicado el 1 de enero de 2011

Consistent SMARCB1 homozygous deletions in epithelioid sarcoma and in a subset of myoepithelial carcinomas can be reliably detected by FISH in archival material

artículo científico publicado en 2014

Copy number losses define subgroups of dedifferentiated liposarcoma with poor prognosis and genomic instability.

artículo científico publicado en 2012

Derivation of sarcomas from mesenchymal stem cells via inactivation of the Wnt pathway

artículo científico publicado en 2007

Diagnosis and management of lipomatous tumors.

artículo científico publicado en 2008

Dichotomy of Genetic Abnormalities in PEComas With Therapeutic Implications

artículo científico publicado en 2015

Differentiation and reversal of malignant changes in colon cancer through PPARgamma

artículo científico publicado en 1998

Distant metastasis in retroperitoneal dedifferentiated liposarcoma is rare and rapidly fatal: a clinicopathological study with emphasis on the low-grade myxofibrosarcoma-like pattern as an early sign of dedifferentiation

artículo científico publicado en 2005

Drug synergy screen and network modeling in dedifferentiated liposarcoma identifies CDK4 and IGF1R as synergistic drug targets.

scientific article published on 24 September 2013

Effectiveness of palliative procedures for intra-abdominal sarcomas.

artículo científico publicado en 2005

Efficacy and safety of imatinib mesylate in advanced gastrointestinal stromal tumors

artículo científico publicado en 2002

Empirical insights into the stochasticity of small RNA sequencing

artículo científico publicado en 2016

Evaluation of a Clinically Applicable Post-Surgical Classification System for Primary Retroperitoneal Soft-Tissue Sarcoma

artículo científico publicado en 2004

Expression profiling of liposarcoma yields a multigene predictor of patient outcome and identifies genes that contribute to liposarcomagenesis.

artículo científico publicado en 2011

Extraskeletal myxoid chondrosarcoma with non-EWSR1-NR4A3 variant fusions correlate with rhabdoid phenotype and high-grade morphology

artículo científico publicado en 2014

Fat-free MRI based on magnetization exchange

artículo científico publicado en 2010

Flavopiridol targets c-KIT transcription and induces apoptosis in gastrointestinal stromal tumor cells.

artículo científico publicado en 2006

Frequent alterations and epigenetic silencing of differentiation pathway genes in structurally rearranged liposarcomas

artículo científico publicado en 2011

Functional copy-number alterations in cancer

artículo científico publicado en 2008

Gene expression profiling of liposarcoma identifies distinct biological types/subtypes and potential therapeutic targets in well-differentiated and dedifferentiated liposarcoma.

artículo científico publicado en 2007

Gradient, high-resolution, magic angle spinning 1H nuclear magnetic resonance spectroscopy of intact cells

artículo científico publicado en 1998

Gradient, high-resolution, magic-angle spinning nuclear magnetic resonance spectroscopy of human adipocyte tissue

artículo científico publicado en 1997

High prevalence of CIC fusion with double-homeobox (DUX4) transcription factors in EWSR1-negative undifferentiated small blue round cell sarcomas.

artículo científico publicado en 2011

High-resolution MAS NMR spectroscopy detection of the spin magnetization exchange by cross-relaxation and chemical exchange in intact cell lines and human tissue specimens

artículo científico publicado en 2006

High-risk features in radiation-associated breast angiosarcomas

scientific article published on 08 October 2013

Histology-based Classification Predicts Pattern of Recurrence and Improves Risk Stratification in Primary Retroperitoneal Sarcoma

artículo científico publicado en 2015

IGF2 over-expression in solitary fibrous tumours is independent of anatomical location and is related to loss of imprinting

artículo científico publicado en 2010

Identification of a novel, recurrent HEY1-NCOA2 fusion in mesenchymal chondrosarcoma based on a genome-wide screen of exon-level expression data

artículo científico publicado en 2011

Identification of recurrent NAB2-STAT6 gene fusions in solitary fibrous tumor by integrative sequencing

artículo científico publicado en 2013

Impact of Intensity-Modulated Radiation Therapy on Local Control in Primary Soft-Tissue Sarcoma of the Extremity

article

Influence of site on the therapeutic ratio of adjuvant radiotherapy in soft-tissue sarcoma of the extremity

artículo científico publicado en 2005

Intensity Modulated Radiation Therapy for Primary Soft Tissue Sarcoma of the Extremity: Preliminary Results

artículo científico publicado en 2007

Isotropic susceptibility shift under MAS: the origin of the split water resonances in 1H MAS NMR spectra of cell suspensions.

artículo científico publicado en 2003

KDR activating mutations in human angiosarcomas are sensitive to specific kinase inhibitors

artículo científico publicado en 2009

Kinase mutations and imatinib response in patients with metastatic gastrointestinal stromal tumor

artículo científico publicado en 2003

Lessons learned from the study of 10,000 patients with soft tissue sarcoma.

artículo científico publicado en 2014

Liposarcoma subtypes: identification with computed tomography and ultrasound-guided percutaneous needle biopsy

artículo científico publicado en 2004

Local control comparison of adjuvant brachytherapy to intensity-modulated radiotherapy in primary high-grade sarcoma of the extremity

scientific article published on 24 January 2011

Long-term outcomes in extremity soft tissue sarcoma after a pathologically negative re-resection and without radiotherapy

scientific article published on June 2008

Long-term salvageability for patients with locally recurrent soft-tissue sarcomas

scientific article published on 01 May 1992

Mechanisms of oncogenic KIT signal transduction in primary gastrointestinal stromal tumors (GISTs).

artículo científico publicado en 2004

Multiple primary soft tissue sarcomas

scientific article published on 01 December 2004

Near universal detection of alterations in CTNNB1 and Wnt pathway regulators in desmoid-type fibromatosis by whole-exome sequencing and genomic analysis

artículo científico publicado en 2015

Neo-adjuvant chemotherapy for primary high-grade extremity soft tissue sarcoma

artículo científico publicado en 2004

Novel MIR143-NOTCH fusions in benign and malignant glomus tumors

artículo científico publicado en 2013

Novel ZC3H7B-BCOR, MEAF6-PHF1, and EPC1-PHF1 fusions in ossifying fibromyxoid tumors--molecular characterization shows genetic overlap with endometrial stromal sarcoma.

artículo científico publicado en 2013

Novel oncogene and tumor suppressor mutations in KIT and PDGFRA wild type gastrointestinal stromal tumors revealed by next generation sequencing.

artículo científico publicado en 2014

Oncologic outcomes of sporadic, neurofibromatosis-associated, and radiation-induced malignant peripheral nerve sheath tumors

artículo científico publicado en 2012

Optimal Percent Myxoid Component to Predict Outcome in High-Grade Myxofibrosarcoma and Undifferentiated Pleomorphic Sarcoma.

artículo científico publicado en 2016

Outcome of Metastatic GIST in the Era before Tyrosine Kinase Inhibitors

article

PDGFRA activating mutations in gastrointestinal stromal tumors.

artículo científico publicado en 2003

PRC2 is recurrently inactivated through EED or SUZ12 loss in malignant peripheral nerve sheath tumors.

artículo científico publicado en 2014

Pathologic and Molecular Heterogeneity in Imatinib-Stable or Imatinib-Responsive Gastrointestinal Stromal Tumors

scientific article published on 01 January 2007

Patterns of deregulation of insulin growth factor signalling pathway in paediatric and adult gastrointestinal stromal tumours.

artículo científico publicado en 2012

Pediatric and adolescent synovial sarcoma: multivariate analysis of prognostic factors and survival outcomes.

artículo científico publicado en 2012

Perioperative chemotherapy in patients undergoing pulmonary resection for metastatic soft-tissue sarcoma of the extremity : a retrospective analysis

artículo científico publicado en 2007

Phase II trial of the CDK4 inhibitor PD0332991 in patients with advanced CDK4-amplified well-differentiated or dedifferentiated liposarcoma.

artículo científico publicado en 2013

Preclinical study of treatment response in HCT-116 cells and xenografts with (1) H-decoupled (31) P MRS.

artículo científico publicado en 2011

Predicting outcome by growth rate of locally recurrent retroperitoneal liposarcoma: the one centimeter per month rule.

artículo científico publicado en 2009

Predictors of survival and recurrence in primary leiomyosarcoma.

artículo científico publicado en 2013

Prognostic Factors for Survival in Patients With Locally Recurrent Extremity Soft Tissue Sarcomas

artículo científico publicado en 2005

Prognostic factors and survival in pediatric and adolescent liposarcoma

artículo científico publicado en 2012

Prognostic value of KIT mutation type, mitotic activity, and histologic subtype in gastrointestinal stromal tumors

artículo científico publicado en 2002

Reconstruction after soft tissue sarcoma resection in the setting of brachytherapy: a 10-year experience

artículo científico publicado en 2004

Recurrent CIC Gene Abnormalities in Angiosarcomas: A Molecular Study of 120 Cases With Concurrent Investigation of PLCG1, KDR, MYC, and FLT4 Gene Alterations.

artículo científico publicado en 2016

Resolution of creatine and phosphocreatine 1H signals in isolated human skeletal muscle using HR-MAS 1H NMR.

artículo científico publicado en 2008

Restoration of C/EBPα in dedifferentiated liposarcoma induces G2/M cell cycle arrest and apoptosis ⬇️

artículo científico publicado el 14 de diciembre de 2011

Results of tyrosine kinase inhibitor therapy followed by surgical resection for metastatic gastrointestinal stromal tumor

article

SDHA loss of function mutations in a subset of young adult wild-type gastrointestinal stromal tumors

artículo científico publicado en 2012

Skeletal metastases in myxoid liposarcoma: an unusual pattern of distant spread.

artículo científico publicado en 2007

Small RNA sequencing and functional characterization reveals MicroRNA-143 tumor suppressor activity in liposarcoma

artículo científico publicado en 2011

Soft tissue sarcoma diagnosed subsequent to lymphoma is associated with prior radiotherapy and decreased survival

artículo científico publicado en 2011

Soft tissue sarcoma of the head & neck: nomogram validation and analysis of staging systems

artículo científico publicado en 2015

Sorafenib Inhibits the Imatinib-Resistant KITT670I Gatekeeper Mutation in Gastrointestinal Stromal Tumor

artículo científico publicado en 2007

Sorafenib inhibits growth and mitogen-activated protein kinase signaling in malignant peripheral nerve sheath cells

artículo científico publicado en 2008

Spindle cell rhabdomyosarcoma (so-called) in adults: report of two cases with emphasis on differential diagnosis

scientific article published on 01 April 1998

Subtype specific prognostic nomogram for patients with primary liposarcoma of the retroperitoneum, extremity, or trunk

artículo científico publicado en 2006

Subtype-specific genomic alterations define new targets for soft-tissue sarcoma therapy

artículo científico publicado en 2010

Surface-enhanced resonance Raman scattering nanostars for high-precision cancer imaging.

artículo científico publicado en 2015

Targeted exome sequencing profiles genetic alterations in leiomyosarcoma

artículo científico publicado en 2015

Terminal differentiation of human liposarcoma cells induced by ligands for peroxisome proliferator-activated receptor gamma and the retinoid X receptor.

artículo científico publicado en 1997

The cyclin-dependent kinase inhibitor flavopiridol potentiates doxorubicin efficacy in advanced sarcomas: preclinical investigations and results of a phase I dose-escalation clinical trial

artículo científico publicado en 2012

The impact of chemotherapy on the survival of patients with high-grade primary extremity liposarcoma.

artículo científico publicado en 2004

The landscape of somatic copy-number alteration across human cancers

artículo científico publicado en 2010

The miR-17-92 cluster and its target THBS1 are differentially expressed in angiosarcomas dependent on MYC amplification

artículo científico publicado en 2012

Translocation t(8;13)(p11;q11-12) in stem cell leukemia/lymphoma of T-cell and myeloid lineages

scientific article published on 01 February 1995

Tumor mitotic rate, size, and location independently predict recurrence after resection of primary gastrointestinal stromal tumor (GIST).

artículo científico publicado en 2008

Vaccination with irradiated, autologous melanoma cells engineered to secrete granulocyte-macrophage colony-stimulating factor by adenoviral-mediated gene transfer augments antitumor immunity in patients with metastatic melanoma.

artículo científico publicado en 2003

Validation of the postoperative nomogram for 12-year sarcoma-specific mortality

artículo científico publicado en 2004

Water suppression without signal loss in HR-MAS 1H NMR of cells and tissues.

artículo científico publicado en 2004

Why do patients with low-grade soft tissue sarcoma die?

artículo científico publicado en 2008

mRNA and protein levels of FUS, EWSR1, and TAF15 are upregulated in liposarcoma ⬇️

artículo científico publicado el 22 de febrero de 2011

Lista de obras de Samuel Singer

13C- and 31P-NMR studies of human colon cancer in-vitro and in-vivo

A Phase Ib/II Study of Gemcitabine and Docetaxel in Combination With Pazopanib for the Neoadjuvant Treatment of Soft Tissue Sarcomas

A developmental model of sarcomagenesis defines a differentiation-based classification for liposarcomas.

A differentiation-based phylogeny of cancer subtypes

A recurrent neomorphic mutation in MYOD1 defines a clinically aggressive subset of embryonal rhabdomyosarcoma associated with PI3K-AKT pathway mutations

A tribute to Murray F. Brennan, MD.

Acquired resistance to imatinib in gastrointestinal stromal tumor occurs through secondary gene mutation

Activity of Sorafenib against desmoid tumor/deep fibromatosis

Adult rhabdomyosarcoma survival improved with treatment on multimodality protocols.

Adults with Ewing's sarcoma/primitive neuroectodermal tumor: adverse effect of older age and primary extraosseous disease on outcome

Advanced well-differentiated/dedifferentiated liposarcomas: role of chemotherapy and survival

Advances in sarcoma genomics and new therapeutic targets

An Empirical Evaluation of normalization Methods for MicroRNA Arrays in a Liposarcoma Study ⬇️

Angiogenic profile of soft tissue sarcomas based on analysis of circulating factors and microarray gene expression.

Atypical lipomatous tumor/well-differentiated liposarcoma of the extremity and trunk wall: importance of histological subtype with treatment recommendations.

Biochemical analysis using high-resolution magic angle spinning NMR spectroscopy distinguishes lipoma-like well-differentiated liposarcoma from normal fat.

Blood neutrophil-to-lymphocyte ratio is prognostic in gastrointestinal stromal tumor.

Circulating angiogenic factor levels correlate with extent of disease and risk of recurrence in patients with soft tissue sarcoma

Clinical and molecular approaches to well differentiated and dedifferentiated liposarcoma.

Comparison of Perioperative Radiation Therapy and Surgery Versus Surgery Alone in 204 Patients With Primary Retroperitoneal Sarcoma: A Retrospective 2-Institution Study

Comparison of local recurrence with conventional and intensity-modulated radiation therapy for primary soft-tissue sarcomas of the extremity

Consistent MYC and FLT4 gene amplification in radiation‐induced angiosarcoma but not in other radiation‐associated atypical vascular lesions ⬇️

Consistent SMARCB1 homozygous deletions in epithelioid sarcoma and in a subset of myoepithelial carcinomas can be reliably detected by FISH in archival material

Copy number losses define subgroups of dedifferentiated liposarcoma with poor prognosis and genomic instability.

Derivation of sarcomas from mesenchymal stem cells via inactivation of the Wnt pathway

Diagnosis and management of lipomatous tumors.

Dichotomy of Genetic Abnormalities in PEComas With Therapeutic Implications

Differentiation and reversal of malignant changes in colon cancer through PPARgamma

Distant metastasis in retroperitoneal dedifferentiated liposarcoma is rare and rapidly fatal: a clinicopathological study with emphasis on the low-grade myxofibrosarcoma-like pattern as an early sign of dedifferentiation

Drug synergy screen and network modeling in dedifferentiated liposarcoma identifies CDK4 and IGF1R as synergistic drug targets.

Effectiveness of palliative procedures for intra-abdominal sarcomas.

Efficacy and safety of imatinib mesylate in advanced gastrointestinal stromal tumors

Empirical insights into the stochasticity of small RNA sequencing

Evaluation of a Clinically Applicable Post-Surgical Classification System for Primary Retroperitoneal Soft-Tissue Sarcoma

Expression profiling of liposarcoma yields a multigene predictor of patient outcome and identifies genes that contribute to liposarcomagenesis.

Extraskeletal myxoid chondrosarcoma with non-EWSR1-NR4A3 variant fusions correlate with rhabdoid phenotype and high-grade morphology

Fat-free MRI based on magnetization exchange

Flavopiridol targets c-KIT transcription and induces apoptosis in gastrointestinal stromal tumor cells.

Frequent alterations and epigenetic silencing of differentiation pathway genes in structurally rearranged liposarcomas

Functional copy-number alterations in cancer

Gene expression profiling of liposarcoma identifies distinct biological types/subtypes and potential therapeutic targets in well-differentiated and dedifferentiated liposarcoma.

Gradient, high-resolution, magic angle spinning 1H nuclear magnetic resonance spectroscopy of intact cells

Gradient, high-resolution, magic-angle spinning nuclear magnetic resonance spectroscopy of human adipocyte tissue

High prevalence of CIC fusion with double-homeobox (DUX4) transcription factors in EWSR1-negative undifferentiated small blue round cell sarcomas.

High-resolution MAS NMR spectroscopy detection of the spin magnetization exchange by cross-relaxation and chemical exchange in intact cell lines and human tissue specimens

High-risk features in radiation-associated breast angiosarcomas

Histology-based Classification Predicts Pattern of Recurrence and Improves Risk Stratification in Primary Retroperitoneal Sarcoma

IGF2 over-expression in solitary fibrous tumours is independent of anatomical location and is related to loss of imprinting

Identification of a novel, recurrent HEY1-NCOA2 fusion in mesenchymal chondrosarcoma based on a genome-wide screen of exon-level expression data

Identification of recurrent NAB2-STAT6 gene fusions in solitary fibrous tumor by integrative sequencing

Impact of Intensity-Modulated Radiation Therapy on Local Control in Primary Soft-Tissue Sarcoma of the Extremity

Influence of site on the therapeutic ratio of adjuvant radiotherapy in soft-tissue sarcoma of the extremity

Intensity Modulated Radiation Therapy for Primary Soft Tissue Sarcoma of the Extremity: Preliminary Results

Isotropic susceptibility shift under MAS: the origin of the split water resonances in 1H MAS NMR spectra of cell suspensions.

KDR activating mutations in human angiosarcomas are sensitive to specific kinase inhibitors

Kinase mutations and imatinib response in patients with metastatic gastrointestinal stromal tumor

Lessons learned from the study of 10,000 patients with soft tissue sarcoma.

Liposarcoma subtypes: identification with computed tomography and ultrasound-guided percutaneous needle biopsy

Local control comparison of adjuvant brachytherapy to intensity-modulated radiotherapy in primary high-grade sarcoma of the extremity

Long-term outcomes in extremity soft tissue sarcoma after a pathologically negative re-resection and without radiotherapy

Long-term salvageability for patients with locally recurrent soft-tissue sarcomas

Mechanisms of oncogenic KIT signal transduction in primary gastrointestinal stromal tumors (GISTs).

Multiple primary soft tissue sarcomas

Near universal detection of alterations in CTNNB1 and Wnt pathway regulators in desmoid-type fibromatosis by whole-exome sequencing and genomic analysis

Neo-adjuvant chemotherapy for primary high-grade extremity soft tissue sarcoma

Novel MIR143-NOTCH fusions in benign and malignant glomus tumors

Novel ZC3H7B-BCOR, MEAF6-PHF1, and EPC1-PHF1 fusions in ossifying fibromyxoid tumors--molecular characterization shows genetic overlap with endometrial stromal sarcoma.

Novel oncogene and tumor suppressor mutations in KIT and PDGFRA wild type gastrointestinal stromal tumors revealed by next generation sequencing.

Oncologic outcomes of sporadic, neurofibromatosis-associated, and radiation-induced malignant peripheral nerve sheath tumors

Optimal Percent Myxoid Component to Predict Outcome in High-Grade Myxofibrosarcoma and Undifferentiated Pleomorphic Sarcoma.

Outcome of Metastatic GIST in the Era before Tyrosine Kinase Inhibitors

PDGFRA activating mutations in gastrointestinal stromal tumors.

PRC2 is recurrently inactivated through EED or SUZ12 loss in malignant peripheral nerve sheath tumors.

Pathologic and Molecular Heterogeneity in Imatinib-Stable or Imatinib-Responsive Gastrointestinal Stromal Tumors

Patterns of deregulation of insulin growth factor signalling pathway in paediatric and adult gastrointestinal stromal tumours.

Pediatric and adolescent synovial sarcoma: multivariate analysis of prognostic factors and survival outcomes.

Perioperative chemotherapy in patients undergoing pulmonary resection for metastatic soft-tissue sarcoma of the extremity : a retrospective analysis

Phase II trial of the CDK4 inhibitor PD0332991 in patients with advanced CDK4-amplified well-differentiated or dedifferentiated liposarcoma.

Preclinical study of treatment response in HCT-116 cells and xenografts with (1) H-decoupled (31) P MRS.