Lista de obras - Michael T. Zimmermann - Dominio Público Uruguay

"The molecule's the thing:" the promise of molecular modeling and dynamic simulations in aiding the prioritization and interpretation of genomic testing results

artículo científico publicado en 2016

A Novel Kleefstra Syndrome-associated Variant That Affects the Conserved TPLX Motif within the Ankyrin Repeat of EHMT1 Leads to Abnormal Protein Folding

scientific article published on 05 January 2017

A computational investigation on the connection between dynamics properties of ribosomal proteins and ribosome assembly

artículo científico publicado en 2012

Aurora kinase B-phosphorylated HP1α functions in chromosomal instability

artículo científico publicado en 2019

Clinical proteome informatics workbench detects pathogenic mutations in hereditary amyloidoses

artículo científico publicado en 2014

Computational and experimental characterization of RNA cubic nanoscaffolds

artículo científico publicado en 2013

Crystal structure of the CusBA heavy-metal efflux complex of Escherichia coli ⬇️

artículo científico publicado el 24 de febrero de 2011

Crystal structures of the CusA efflux pump suggest methionine-mediated metal transport ⬇️

artículo científico publicado el 23 de septiembre de 2010

De novo RRAGC mutation activates mTORC1 signaling in syndromic fetal dilated cardiomyopathy.

artículo científico publicado en 2016

Elastic network models capture the motions apparent within ensembles of RNA structures

artículo científico publicado en 2014

Factors correlating with significant differences between X-ray structures of myoglobin

artículo científico publicado en 2014

Free energies for coarse-grained proteins by integrating multibody statistical contact potentials with entropies from elastic network models.

artículo científico publicado en 2011

Functional validation of TERT and TERC variants of uncertain significance in patients with short telomere syndromes

artículo científico publicado en 2020

Gain and loss of TASK3 channel function and its regulation by novel variation cause KCNK9 imprinting syndrome

scientific article published on 13 June 2022

Gene signatures associated with adaptive humoral immunity following seasonal influenza A/H1N1 vaccination.

artículo científico publicado en 2016

Genome-wide associations of CD46 and IFI44L genetic variants with neutralizing antibody response to measles vaccine

artículo científico publicado en 2017

Hereditary Lysozyme Amyloidosis Variant p.Leu102Ser Associates with Unique Phenotype

artículo científico publicado en 2017

Human telomerase model shows the role of the TEN domain in advancing the double helix for the next polymerization step.

artículo científico publicado en 2011

ICGA-PSO-ELM approach for accurate multiclass cancer classification resulting in reduced gene sets in which genes encoding secreted proteins are highly represented

artículo científico publicado en 2011

Impact of integrated translational research on clinical exome sequencing

artículo científico publicado en 2020

Impact of integrated translational research on clinical exome sequencing

scientific article published in 2023

Integration of Immune Cell Populations, mRNA-Seq, and CpG Methylation to Better Predict Humoral Immunity to Influenza Vaccination: Dependence of mRNA-Seq/CpG Methylation on Immune Cell Populations

artículo científico publicado en 2017

MACE: model based analysis of ChIP-exo

artículo científico publicado en 2014

Molecular modeling and molecular dynamic simulation of the effects of variants in the TGFBR2 kinase domain as a paradigm for interpretation of variants obtained by next generation sequencing.

artículo científico publicado en 2017

Molecular modeling of LDLR aids interpretation of genomic variants

article

Novel NR2F1 variants likely disrupt DNA binding: molecular modeling in two cases, review of published cases, genotype-phenotype correlation, and phenotypic expansion of the Bosch-Boonstra-Schaaf optic atrophy syndrome.

artículo científico publicado en 2017

Novel Type of Renal Amyloidosis Derived from Apolipoprotein-CII.

artículo científico publicado en 2016

PANDA: pathway and annotation explorer for visualizing and interpreting gene-centric data.

artículo científico publicado en 2015

Pathogenic SPTBN1 variants cause an autosomal dominant neurodevelopmental syndrome

artículo científico publicado en 2021

RITAN: rapid integration of term annotation and network resources

scientific article published on 19 July 2019

Recessive MYH6 Mutations in Hypoplastic Left Heart With Reduced Ejection Fraction.

artículo científico publicado en 2015

Recurrent MSC E116K mutations in ALK-negative anaplastic large cell lymphoma

scientific article published on 17 May 2019

Recursive Indirect-Paths Modularity (RIP-M) for Detecting Community Structure in RNA-Seq Co-expression Networks.

artículo científico publicado en 2016

Revealing rotational modes of functionalized gold nanorods on live cell membranes

artículo científico publicado en 2012

Ribosome Mechanics Informs about Mechanism.

artículo científico publicado en 2015

Short paths in protein structure space originate in graph structure

artículo científico publicado en 2009

Structural origins of misfolding propensity in the platelet adhesive von Willebrand factor A1 domain.

artículo científico publicado en 2015

System-Wide Associations between DNA-Methylation, Gene Expression, and Humoral Immune Response to Influenza Vaccination

artículo científico publicado en 2016

TNNI3K mutation in familial syndrome of conduction system disease, atrial tachyarrhythmia and dilated cardiomyopathy

artículo científico publicado en 2014

The Non-Coding RNA Ontology (NCRO): a comprehensive resource for the unification of non-coding RNA biology

artículo científico publicado en 2016

The development of non-coding RNA ontology

scientific article published on January 2016

Understanding protein-nanoparticle interaction: a new gateway to disease therapeutics.

artículo científico publicado en 2014

Whole-exome analysis reveals novel somatic genomic alterations associated with outcome in immunochemotherapy-treated diffuse large B-cell lymphoma.

artículo científico publicado en 2015

Lista de obras de Michael T. Zimmermann

"The molecule's the thing:" the promise of molecular modeling and dynamic simulations in aiding the prioritization and interpretation of genomic testing results

A Novel Kleefstra Syndrome-associated Variant That Affects the Conserved TPLX Motif within the Ankyrin Repeat of EHMT1 Leads to Abnormal Protein Folding

A computational investigation on the connection between dynamics properties of ribosomal proteins and ribosome assembly

Aurora kinase B-phosphorylated HP1α functions in chromosomal instability

Clinical proteome informatics workbench detects pathogenic mutations in hereditary amyloidoses

Computational and experimental characterization of RNA cubic nanoscaffolds

Crystal structure of the CusBA heavy-metal efflux complex of Escherichia coli ⬇️

Crystal structures of the CusA efflux pump suggest methionine-mediated metal transport ⬇️

De novo RRAGC mutation activates mTORC1 signaling in syndromic fetal dilated cardiomyopathy.

Elastic network models capture the motions apparent within ensembles of RNA structures

Factors correlating with significant differences between X-ray structures of myoglobin

Free energies for coarse-grained proteins by integrating multibody statistical contact potentials with entropies from elastic network models.

Functional validation of TERT and TERC variants of uncertain significance in patients with short telomere syndromes

Gain and loss of TASK3 channel function and its regulation by novel variation cause KCNK9 imprinting syndrome

Gene signatures associated with adaptive humoral immunity following seasonal influenza A/H1N1 vaccination.

Genome-wide associations of CD46 and IFI44L genetic variants with neutralizing antibody response to measles vaccine

Hereditary Lysozyme Amyloidosis Variant p.Leu102Ser Associates with Unique Phenotype

Human telomerase model shows the role of the TEN domain in advancing the double helix for the next polymerization step.

ICGA-PSO-ELM approach for accurate multiclass cancer classification resulting in reduced gene sets in which genes encoding secreted proteins are highly represented

Impact of integrated translational research on clinical exome sequencing

Impact of integrated translational research on clinical exome sequencing

Integration of Immune Cell Populations, mRNA-Seq, and CpG Methylation to Better Predict Humoral Immunity to Influenza Vaccination: Dependence of mRNA-Seq/CpG Methylation on Immune Cell Populations

MACE: model based analysis of ChIP-exo

Molecular modeling and molecular dynamic simulation of the effects of variants in the TGFBR2 kinase domain as a paradigm for interpretation of variants obtained by next generation sequencing.

Molecular modeling of LDLR aids interpretation of genomic variants

Novel NR2F1 variants likely disrupt DNA binding: molecular modeling in two cases, review of published cases, genotype-phenotype correlation, and phenotypic expansion of the Bosch-Boonstra-Schaaf optic atrophy syndrome.

Novel Type of Renal Amyloidosis Derived from Apolipoprotein-CII.

PANDA: pathway and annotation explorer for visualizing and interpreting gene-centric data.

Pathogenic SPTBN1 variants cause an autosomal dominant neurodevelopmental syndrome

RITAN: rapid integration of term annotation and network resources

Recessive MYH6 Mutations in Hypoplastic Left Heart With Reduced Ejection Fraction.

Recurrent MSC E116K mutations in ALK-negative anaplastic large cell lymphoma

Recursive Indirect-Paths Modularity (RIP-M) for Detecting Community Structure in RNA-Seq Co-expression Networks.

Revealing rotational modes of functionalized gold nanorods on live cell membranes

Ribosome Mechanics Informs about Mechanism.

Short paths in protein structure space originate in graph structure

Structural origins of misfolding propensity in the platelet adhesive von Willebrand factor A1 domain.

System-Wide Associations between DNA-Methylation, Gene Expression, and Humoral Immune Response to Influenza Vaccination

TNNI3K mutation in familial syndrome of conduction system disease, atrial tachyarrhythmia and dilated cardiomyopathy

The Non-Coding RNA Ontology (NCRO): a comprehensive resource for the unification of non-coding RNA biology

The development of non-coding RNA ontology

Understanding protein-nanoparticle interaction: a new gateway to disease therapeutics.

Whole-exome analysis reveals novel somatic genomic alterations associated with outcome in immunochemotherapy-treated diffuse large B-cell lymphoma.