Filtros de búsqueda

Lista de obras de Guido Grandi

125Single Nucleotide Polymorphisms Drive Phenotypic Diversity Among Sequence Type 1 Group B Streptococcus, An Emerging Cause of Invasive Disease in Adult Humans

artículo científico publicado en 2014

A Bacillus subtilis large ORF coding for a polypeptide highly similar to polyketide synthases

artículo científico publicado en 1993

A chemokine-degrading extracellular protease made by group A Streptococcus alters pathogenesis by enhancing evasion of the innate immune response

artículo científico publicado en 2008

A new flow-cytometry-based opsonophagocytosis assay for the rapid measurement of functional antibody levels against Group B Streptococcus.

artículo científico publicado en 2012

A new human growth hormone production process using a recombinant Bacillus subtilis strain

article

A putative new peptide synthase operon in Bacillus subtilis: partial characterization.

artículo científico publicado en 1995

A rapid and versatile site-directed method of mutagenesis for double-stranded plasmid DNA.

artículo científico publicado en 1988

An operon encoding a novel ABC-type transport system in Bacillus subtilis

artículo científico publicado en 1995

Analysis of two-component systems in group B Streptococcus shows that RgfAC and the novel FspSR modulate virulence and bacterial fitness.

artículo científico publicado en 2014

Antibody-mediated immunity induced by engineered Escherichia coli OMVs carrying heterologous antigens in their lumen

artículo científico publicado en 2014

Approach to discover T- and B-cell antigens of intracellular pathogens applied to the design of Chlamydia trachomatis vaccines

artículo científico publicado en 2011

Auto-Assembling Detoxified Staphylococcus aureus Alpha-Hemolysin Mimicking the Wild-Type Cytolytic Toxin

artículo científico publicado en 2016

Bacterial surface proteins and vaccines ⬇️

artículo científico publicado el 11 de mayo de 2010

Bacterial vaccine discovery: from "brute force" to high selectivity

artículo científico publicado en 2010

BibA Induces Opsonizing Antibodies Conferring In Vivo Protection against Group BStreptococcus

article

BibA: a novel immunogenic bacterial adhesin contributing to group B Streptococcus survival in human blood

article

CD81 extracellular domain 3D structure: insight into the tetraspanin superfamily structural motifs.

artículo científico publicado en 2001

CT043, a protective antigen that induces a CD4+ Th1 response during Chlamydia trachomatis infection in mice and humans.

artículo científico publicado en 2009

Capturing host-pathogen interactions by protein microarrays: identification of novel streptococcal proteins binding to human fibronectin, fibrinogen, and C4BP.

artículo científico publicado en 2009

Characterization and identification of vaccine candidate proteins through analysis of the group A Streptococcus surface proteome.

artículo científico publicado en 2006

Characterization of a novel Neisseria meningitidis Fur and iron-regulated operon required for protection from oxidative stress: utility of DNA microarray in the assignment of the biological role of hypothetical genes.

artículo científico publicado en 2004

Characterization of the locus encoding the [Ni-Fe] sulfhydrogenase from the archaeon Pyrococcus furiosus: evidence for a relationship to bacterial sulfite reductases

artículo científico publicado en 1995

Characterization of the srfA locus of Bacillus subtilis: only the valine-activating domain of srfA is involved in the establishment of genetic competence

artículo científico publicado en 1993

Characterization of the surfactin synthetase multi-enzyme complex

artículo científico publicado en 1994

Chlamydia pneumoniae genome sequence analysis and identification of HLA-A2-restricted CD8+ T cell epitopes recognized by infection-primed T cells.

scientific article published on October 2005

Combined conjugate vaccines: enhanced immunogenicity with the N19 polyepitope as a carrier protein

artículo científico publicado en 2005

Comparative genomics of Neisseria meningitidis: core genome, islands of horizontal transfer and pathogen-specific genes

article

Complete Genome Sequence of Neisseria meningitidis Serogroup B Strain MC58

artículo científico publicado en 2000

Complete genome sequence and comparative genomic analysis of an emerging human pathogen, serotype V Streptococcus agalactiae

artículo científico publicado en 2002

Coordinate transcription and physical linkage of domains in surfactin synthetase are not essential for proper assembly and activity of the multienzyme complex

artículo científico publicado en 1998

Crystal structures of the components of the Staphylococcus aureus leukotoxin ED.

artículo científico publicado en 2016

Crystallization and preliminary crystallographic studies on the large extracellular domain of human CD81, a tetraspanin receptor for hepatitis C virus.

artículo científico publicado en 2001

CsrRS regulates group B Streptococcus virulence gene expression in response to environmental pH: a new perspective on vaccine development

scientific article published on 19 June 2009

Cumulative stabilizing effects of glycine to alanine substitutions in Bacillus subtilis neutral protease

artículo científico publicado en 1992

Cumulative stabilizing effects of hydrophobic interactions on the surface of the neutral protease from Bacillus subtilis

artículo científico publicado en 1996

Different profile of CD8+ effector T cells induced in Der p 1-allergic and naïve mice by DNA vaccination

artículo científico publicado en 2002

Different specific activities of the monomeric and oligomeric forms of plasmid DNA in transformation of B. subtilis and E. coli ⬇️

artículo científico publicado el 24 de julio de 1979

Discovery of a vaccine antigen that protects mice from Chlamydia pneumoniae infection.

artículo científico publicado en 2006

Effect of Glu-143 and His-231 substitutions on the catalytic activity and secretion of Bacillus subtilis neutral protease

artículo científico publicado en 1989

Efficient conversion of 5-substituted hydantoins to D-alpha-amino acids using recombinant Escherichia coli strains

artículo científico publicado en 1998

Environmental acidification drives S. pyogenes pilus expression and microcolony formation on epithelial cells in a FCT-dependent manner

artículo científico publicado en 2010

Evaluation of a Group A Streptococcus synthetic oligosaccharide as vaccine candidate

artículo científico publicado en 2010

Experimental infection by Chlamydia pneumoniae in the hamster

scientific article published on March 2004

Exploiting Antigenic Diversity for Vaccine Design: THE CHLAMYDIA ArtJ PARADIGM

artículo científico publicado en 2010

Expression of Bordetella pertussis fimbrial (fim) genes in Bordetella bronchiseptica: fimX is expressed at a low level and vir-regulated

artículo científico publicado en 1991

Four-component Staphylococcus aureus vaccine 4C-staph enhances Fcγ receptor expression in neutrophils and monocytes and mitigates S. aureus infection in neutropenic mice

artículo científico publicado en 2015

Functional activity of maternal and cord antibodies elicited by an investigational group B streptococcus trivalent glycoconjugate vaccine in pregnant women

artículo científico publicado en 2018

Functional characterization of a newly identified group B Streptococcus pullulanase eliciting antibodies able to prevent alpha-glucans degradation

artículo científico publicado en 2008

GNA33 from Neisseria meningitidis serogroup B encodes a membrane-bound lytic transglycosylase (MltA).

artículo científico publicado en 2002

GNA33 of Neisseria meningitidis is a lipoprotein required for cell separation, membrane architecture, and virulence.

artículo científico publicado en 2004

Gene expression profile in Neisseria meningitidis and Neisseria lactamica upon host-cell contact: from basic research to vaccine development.

artículo científico publicado en 2002

Genome Analysis Reveals Pili in Group B Streptococcus

artículo científico publicado en 2005

Genome analysis of multiple pathogenic isolates of Streptococcus agalactiae: implications for the microbial "pan-genome"

artículo científico publicado en 2005

Genomic analysis reveals the molecular basis for capsule loss in the group B Streptococcus population

artículo científico publicado en 2015

Genomic approach for analysis of surface proteins in Chlamydia pneumoniae

artículo científico publicado en 2002

Group A Streptococcus produce pilus-like structures containing protective antigens and Lancefield T antigens

artículo científico publicado en 2005

Group B Streptococcus Pullulanase Crystal Structures in the Context of a Novel Strategy for Vaccine Development

artículo científico publicado en 2009

Group B Streptococcus crosses human epithelial cells by a paracellular route

artículo científico publicado en 2005

Group B Streptococcus: global incidence and vaccine development

artículo científico publicado en 2006

Helicobacter pyloritoxin VacA induces vacuole formation by acting in the cell cytosol

artículo científico publicado en 1997

Identification of 2 hypothetical genes involved in Neisseria meningitidis cathelicidin resistance.

artículo científico publicado en 2008

Identification of a universal Group B streptococcus vaccine by multiple genome screen

artículo científico publicado en 2005

Identification of iron-activated and -repressed Fur-dependent genes by transcriptome analysis of Neisseria meningitidis group B.

artículo científico publicado en 2003

Identification of new potential vaccine candidates against Chlamydia pneumoniae by multiple screenings.

artículo científico publicado en 2005

Identification of novel genomic islands coding for antigenic pilus-like structures in Streptococcus agalactiae.

artículo científico publicado en 2006

Identification of vaccine candidates against serogroup B meningococcus by whole-genome sequencing.

artículo científico publicado en 2000

Immobilized metal-ion affinity chromatography of human growth hormone

scientific article published on 01 June 1989

In vitro transcription and translation coupled to two-dimensional electrophoresis for bacterial proteome analysis.

artículo científico publicado en 2007

Inferring reasons for the failure of Staphylococcus aureus vaccines in clinical trials

artículo científico publicado en 2012

Inhibitory activity of IL-1 receptor antagonist depends on the balance between binding capacity for IL-1 receptor type 1 and IL-1 receptor type II.

artículo científico publicado en 1997

Introduction of unmarked mutations in the Helicobacter pylori vacA gene with a sucrose sensitivity marker

artículo científico publicado en 1997

MF59- and Al(OH)3-Adjuvanted Staphylococcus aureus (4C-Staph) Vaccines Induce Sustained Protective Humoral and Cellular Immune Responses, with a Critical Role for Effector CD4 T Cells at Low Antibody Titers

artículo científico publicado en 2015

Mapping of receptor binding sites on IL-1 beta by reconstruction of IL-1ra-like domains

artículo científico publicado en 1995

Mg2+ signalling defines the group A streptococcal CsrRS (CovRS) regulon

article

Mining the bacterial unknown proteome: identification and characterization of a novel family of highly conserved protective antigens in Staphylococcus aureus

artículo científico publicado en 2013

Model building of a thermolysin-like protease by mutagenesis

artículo científico publicado en 1997

Multi high-throughput approach for highly selective identification of vaccine candidates: the Group A Streptococcus case.

artículo científico publicado en 2012

Multi-plasmid DNA vaccination avoids antigenic competition and enhances immunogenicity of a poorly immunogenic plasmid

article

N19 polyepitope as a carrier for enhanced immunogenicity and protective efficacy of meningococcal conjugate vaccines

artículo científico publicado en 2004

New insights into the role of the glutamic acid of the E-box motif in group B Streptococcus pilus 2a assembly

article

New plasmid expression vectors for Bacillus subtilis

artículo científico publicado en 1986

One Dose of Staphylococcus aureus 4C-Staph Vaccine Formulated with a Novel TLR7-Dependent Adjuvant Rapidly Protects Mice through Antibodies, Effector CD4+ T Cells, and IL-17A.

artículo científico publicado en 2016

Outer membrane vesicles from group B Neisseria meningitidis delta gna33 mutant: proteomic and immunological comparison with detergent-derived outer membrane vesicles.

artículo científico publicado en 2006

Phagocyte subsets and lymphocyte clonal deletion behind ineffective immune response to Staphylococcus aureus

artículo científico

Pili in gram-positive pathogens

artículo científico publicado en 2006

Pilus Backbone Contributes to Group BStreptococcusParacellular Translocation through Epithelial Cells

article

Posttranscriptional regulation of an erythromycin resistance protein specified by plasmic pE194 ⬇️

artículo científico publicado el 1 de julio de 1980

Preventing bacterial infections with pilus-based vaccines: the group B streptococcus paradigm

artículo científico publicado en 2009

Previously unrecognized vaccine candidates against group B meningococcus identified by DNA microarrays

artículo científico publicado en 2002

Prochymosin expression in Bacillus subtilis

artículo científico publicado en 1991

Production processes of recombinant IL-1 beta from Bacillus subtilis: comparison between intracellular and exocellular expression.

artículo científico publicado en 1991

Protective effect of Group B Streptococcus type-III polysaccharide conjugates against maternal colonization, ascending infection and neonatal transmission in rodent models

artículo científico publicado en 2018

Protectome analysis: a new selective bioinformatics tool for bacterial vaccine candidate discovery

artículo científico publicado en 2014

Protein array profiling of tic patient sera reveals a broad range and enhanced immune response against Group A Streptococcus antigens

artículo científico publicado en 2009

Proteome analysis of Neisseria meningitidis serogroup A.

artículo científico publicado en 2004

Proteomics characterization of outer membrane vesicles from the extraintestinal pathogenic Escherichia coli DeltatolR IHE3034 mutant.

artículo científico publicado en 2007

Purification of recombinant human growth hormone by isoelectric focusing in a multicompartment electrolyzer with Immobiline membranes.

artículo científico publicado en 1992

R-factor-mediated suppression of the galactose-sensitive phenotype of Escherichia coli K-12 galE mutants

artículo científico publicado en 1981

Rationally designed strings of promiscuous CD4+ T cell epitopes provide help toHaemophilus influenzae type b oligosaccharide: a model for new conjugate vaccines

artículo científico publicado en 2001

Recombinant and Truncated Tetanus Neurotoxin Light Chain: Cloning, Expression, Purification, and Proteolytic Activity

Recombinant outer membrane vesicles carrying Chlamydia muridarum HtrA induce antibodies that neutralize chlamydial infection in vitro

artículo científico publicado en 2013

Role of FNR and FNR-regulated, sugar fermentation genes in Neisseria meningitidis infection

artículo científico publicado en 2006

Scavenger receptor gp340 aggregates group A streptococci by binding pili.

artículo científico publicado en 2008

Sequence Variation in Group AStreptococcusPili and Association of Pilus Backbone Types with Lancefield T Serotypes

article

Sequence and analysis of the genetic locus responsible for surfactin synthesis in Bacillus subtilis

artículo científico publicado en 1993

Sequence type 1 group B Streptococcus, an emerging cause of invasive disease in adults, evolves by small genetic changes

artículo científico publicado en 2015

Simple sequence repeats and genome plasticity in Streptococcus agalactiae

artículo científico publicado en 2010

Sortase A substrate specificity in GBS pilus 2a cell wall anchoring

artículo científico publicado en 2011

Sortase A utilizes an ancillary protein anchor for efficient cell wall anchoring of pili in Streptococcus agalactiae

artículo científico publicado en 2008

Specific involvement of pilus type 2a in biofilm formation in group B Streptococcus

artículo científico publicado en 2010

Specific pattern of instability of Escherichia coli HisG gene cloned in Bacillus subtilis via the Staphylococcus aureus plasmid pCS194

article

SpyAD, a moonlighting protein of group A Streptococcus contributing to bacterial division and host cell adhesion.

artículo científico publicado en 2014

Staphylococcus aureus FhuD2 is involved in the early phase of staphylococcal dissemination and generates protective immunity in mice.

artículo científico publicado en 2012

Streptococcus agalactiae capsule polymer length and attachment is determined by the proteins CpsABCD.

artículo científico publicado en 2015

Streptococcus pyogenes SpyCEP influences host-pathogen interactions during infection in a murine air pouch model

artículo científico publicado en 2012

Streptococcus pyogenes SpyCEP: a chemokine-inactivating protease with unique structural and biochemical features.

artículo científico publicado en 2010

Streptococcus pyogenes pili promote pharyngeal cell adhesion and biofilm formation

artículo científico publicado en 2007

Structural Basis for Group B Streptococcus Pilus 1 Sortases C Regulation and Specificity

artículo científico publicado en 2012

Structural and functional characterization of the Staphylococcus aureus virulence factor and vaccine candidate FhuD2

artículo científico publicado en 2013

Structural features of neutral protease from Bacillus subtilis deduced from model-building and limited proteolysis experiments.

artículo científico publicado en 1990

Structural vaccinology starts to deliver

artículo científico publicado en 2012

Structure analysis and site-directed mutagenesis of defined key residues and motives for pilus-related sortase C1 in group B Streptococcus

artículo científico publicado en 2011

Structure and protective efficacy of the Staphylococcus aureus autocleaving protease EpiP.

artículo científico publicado en 2014

Structure of the type IX group B Streptococcus capsular polysaccharide and its evolutionary relationship with types V and VII

artículo científico publicado en 2014

Structure, dynamics and immunogenicity of a catalytically inactive CXC chemokine-degrading protease SpyCEP from Streptococcus pyogenes

scientific article published on 13 March 2020

Structure-based approach to rationally design a chimeric protein for an effective vaccine against Group B Streptococcus infections

artículo científico publicado en 2011

Subunit association and conformational flexibility in the head subdomain of human CD81 large extracellular loop

artículo científico publicado en 2002

Surface interactome in Streptococcus pyogenes

artículo científico publicado en 2011

Surfome analysis as a fast track to vaccine discovery: identification of a novel protective antigen for Group B Streptococcus hypervirulent strain COH1.

artículo científico publicado en 2009

Synergistic Protective Activity of Tumor-Specific Epitopes Engineered in Bacterial Outer Membrane Vesicles

artículo científico publicado en 2017

Targeted amino acid substitutions impair streptolysin O toxicity and group A Streptococcus virulence

artículo científico publicado en 2013

The Helicobacter pylori neutrophil-activating protein is an iron-binding protein with dodecameric structure.

artículo científico publicado en 1999

The Human Pathogen Streptococcus pyogenes Releases Lipoproteins as Lipoprotein-rich Membrane Vesicles

artículo científico publicado en 2015

The Protective Value of Maternal Group B Streptococcus Antibodies: Quantitative and Functional Analysis of Naturally Acquired Responses to Capsular Polysaccharides and Pilus Proteins in European Maternal Sera

artículo científico publicado en 2016

The [Ni-Fe] hydrogenase from the thermophilic bacterium Acetomicrobium flavidum

artículo científico publicado en 1996

The ancillary protein 1 of Streptococcus pyogenes FCT-1 pili mediates cell adhesion and biofilm formation through heterophilic as well as homophilic interactions

artículo científico publicado en 2012

The complete genome sequence of the gram-positive bacterium Bacillus subtilis

artículo científico publicado en 1997

The effect of engineering surface loops on the thermal stability of Bacillus subtilis neutral protease

artículo científico publicado en 1994

The impact of genomics in vaccine discovery: achievements and lessons

article

Three-Dimensional Human Skin Models to Understand Staphylococcus aureus Skin Colonization and Infection

artículo científico publicado en 2014

Topological Mapping of the Cysteine Residues ofN-Carbamyl-D-amino-acid Amidohydrolase and Their Role in Enzymatic Activity

artículo científico publicado en 1996

Transcriptional and proteomic profiles of group B Streptococcus type V reveal potential adherence proteins associated with high-level invasion

artículo científico publicado en 2007

Transfection of E. coli with lambda DNA by electroporation

artículo científico publicado en 1992

Translational attenuation of ermC: a deletion analysis

artículo científico publicado en 1982

Typing of the pilus-protein-encoding FCT region and biofilm formation as novel parameters in epidemiological investigations of Streptococcus pyogenes isolates from various infection sites

artículo científico publicado en 2009

Understanding the molecular determinants driving the immunological specificity of the protective pilus 2a backbone protein of group B streptococcus

artículo científico publicado en 2013

Use ofLactococcus lactisExpressing Pili from Group BStreptococcusas a Broad‐Coverage Vaccine against Streptococcal Disease

article

Vaccine composition formulated with a novel TLR7-dependent adjuvant induces high and broad protection against Staphylococcus aureus

artículo científico publicado en 2015

Why is a protective antigen protective?

scientific article published on December 2009

nprR1 and nprR2 regulatory regions for neutral protease expression in Bacillus subtilis.

artículo científico publicado en 1986

Dominio Público Uruguay está sostenido por:

Acerca de Dominio Público Uruguay

Ayuda