Lista de obras - Marcel Schilling - Dominio Público Uruguay

Cellular ERK phospho-form profiles with conserved preference for a switch-like pattern.

artículo científico publicado en 2012

Computational processing and error reduction strategies for standardized quantitative data in biological networks

artículo científico publicado en 2005

Context-specific flow through the MEK/ERK module produces cell- and ligand-specific patterns of ERK single and double phosphorylation

artículo científico publicado en 2016

Covering a broad dynamic range: information processing at the erythropoietin receptor

artículo científico publicado en 2010

Data2Dynamics: a modeling environment tailored to parameter estimation in dynamical systems

artículo científico publicado en 2015

Disentangling molecular mechanisms regulating sensitization of interferon alpha signal transduction

artículo científico publicado en 2020

Disentangling the Complexity of HGF Signaling by Combining Qualitative and Quantitative Modeling

artículo científico publicado en 2015

Division of labor by dual feedback regulators controls JAK2/STAT5 signaling over broad ligand range.

artículo científico publicado en 2011

Dynamic mathematical modeling of IL13-induced signaling in Hodgkin and primary mediastinal B-cell lymphoma allows prediction of therapeutic targets

artículo científico publicado en 2010

Expression ratio of the TGFβ-inducible gene MYO10 is prognostic for overall survival of squamous cell lung cancer patients and predicts chemotherapy response.

artículo científico publicado en 2018

Facilitation of mRNA deadenylation and decay by the exosome-bound, DExH protein RHAU

artículo científico publicado en 2004

Identification of Cell Type-Specific Differences in Erythropoietin Receptor Signaling in Primary Erythroid and Lung Cancer Cells

artículo científico publicado en 2016

Identification of Interleukin1β as an Amplifier of Interferon alpha-induced Antiviral Responses

artículo científico publicado en 2020

Identification of isoform-specific dynamics in phosphorylation-dependent STAT5 dimerization by quantitative mass spectrometry and mathematical modeling

artículo científico publicado en 2014

In silico labeling reveals the time-dependent label half-life and transit-time in dynamical systems.

artículo científico publicado en 2012

Lessons learned from quantitative dynamical modeling in systems biology

artículo científico publicado en 2013

MSPypeline: a python package for streamlined data analysis of mass spectrometry-based proteomics

artículo científico publicado en 2022

Model Based Targeting of IL-6-Induced Inflammatory Responses in Cultured Primary Hepatocytes to Improve Application of the JAK Inhibitor Ruxolitinib.

artículo científico publicado en 2017

Model-based identification of TNFα-induced IKKβ-mediated and IκBα-mediated regulation of NFκB signal transduction as a tool to quantify the impact of drug-induced liver injury compounds.

artículo científico publicado en 2018

Predictive mathematical models of cancer signalling pathways

artículo científico

Protein abundance of AKT and ERK pathway components governs cell type-specific regulation of proliferation

scientific article published on 24 January 2017

Quantitative data generation for systems biology: the impact of randomisation, calibrators and normalisers.

artículo científico publicado en 2005

Resolving the Combinatorial Complexity of Smad Protein Complex Formation and Its Link to Gene Expression

artículo científico publicado en 2017

Short-term information processing, long-term responses: Insights by mathematical modeling of signal transduction. Early activation dynamics of key signaling mediators can be predictive for cell fate decisions

artículo científico publicado en 2012

Structural and practical identifiability analysis of partially observed dynamical models by exploiting the profile likelihood

artículo científico publicado en 2009

T160‐phosphorylated CDK2 defines threshold for HGF dependent proliferation in primary hepatocytes

artículo científico publicado en 2015

Theoretical and experimental analysis links isoform-specific ERK signalling to cell fate decisions

artículo científico publicado en 2009

Lista de obras de Marcel Schilling

Cellular ERK phospho-form profiles with conserved preference for a switch-like pattern.

Computational processing and error reduction strategies for standardized quantitative data in biological networks

Context-specific flow through the MEK/ERK module produces cell- and ligand-specific patterns of ERK single and double phosphorylation

Covering a broad dynamic range: information processing at the erythropoietin receptor

Data2Dynamics: a modeling environment tailored to parameter estimation in dynamical systems

Disentangling molecular mechanisms regulating sensitization of interferon alpha signal transduction

Disentangling the Complexity of HGF Signaling by Combining Qualitative and Quantitative Modeling

Division of labor by dual feedback regulators controls JAK2/STAT5 signaling over broad ligand range.

Dynamic mathematical modeling of IL13-induced signaling in Hodgkin and primary mediastinal B-cell lymphoma allows prediction of therapeutic targets

Expression ratio of the TGFβ-inducible gene MYO10 is prognostic for overall survival of squamous cell lung cancer patients and predicts chemotherapy response.

Facilitation of mRNA deadenylation and decay by the exosome-bound, DExH protein RHAU

Identification of Cell Type-Specific Differences in Erythropoietin Receptor Signaling in Primary Erythroid and Lung Cancer Cells

Identification of Interleukin1β as an Amplifier of Interferon alpha-induced Antiviral Responses

Identification of isoform-specific dynamics in phosphorylation-dependent STAT5 dimerization by quantitative mass spectrometry and mathematical modeling

In silico labeling reveals the time-dependent label half-life and transit-time in dynamical systems.

Lessons learned from quantitative dynamical modeling in systems biology

MSPypeline: a python package for streamlined data analysis of mass spectrometry-based proteomics

Model Based Targeting of IL-6-Induced Inflammatory Responses in Cultured Primary Hepatocytes to Improve Application of the JAK Inhibitor Ruxolitinib.

Model-based identification of TNFα-induced IKKβ-mediated and IκBα-mediated regulation of NFκB signal transduction as a tool to quantify the impact of drug-induced liver injury compounds.

Predictive mathematical models of cancer signalling pathways

Protein abundance of AKT and ERK pathway components governs cell type-specific regulation of proliferation

Quantitative data generation for systems biology: the impact of randomisation, calibrators and normalisers.

Resolving the Combinatorial Complexity of Smad Protein Complex Formation and Its Link to Gene Expression

Short-term information processing, long-term responses: Insights by mathematical modeling of signal transduction. Early activation dynamics of key signaling mediators can be predictive for cell fate decisions

Structural and practical identifiability analysis of partially observed dynamical models by exploiting the profile likelihood

T160‐phosphorylated CDK2 defines threshold for HGF dependent proliferation in primary hepatocytes

Theoretical and experimental analysis links isoform-specific ERK signalling to cell fate decisions