Lista de obras - Jan Brezovsky - Dominio Público Uruguay

Ancestral Haloalkane Dehalogenases Show Robustness and Unique Substrate Specificity.

artículo científico publicado en 2017

Are time-dependent fluorescence shifts at the tunnel mouth of haloalkane dehalogenase enzymes dependent on the choice of the chromophore?

artículo científico publicado en 2013

CAVER 3.0: a tool for the analysis of transport pathways in dynamic protein structures

artículo científico publicado en 2012

CAVER Analyst 1.0: graphic tool for interactive visualization and analysis of tunnels and channels in protein structures.

artículo científico publicado en 2014

CAVER Analyst 2.0: analysis and visualization of channels and tunnels in protein structures and molecular dynamics trajectories

artículo científico publicado en 2018

CAVER: Algorithms for Analyzing Dynamics of Tunnels in Macromolecules

artículo científico publicado en 2016

Catalytic Cycle of Haloalkane Dehalogenases Toward Unnatural Substrates Explored by Computational Modeling

artículo científico publicado en 2017

Computational tools for designing and engineering biocatalysts

artículo científico publicado en 2009

Computational tools for designing smart libraries.

artículo científico publicado en 2014

Computer-Assisted Engineering of Hyperstable Fibroblast Growth Factor 2.

artículo científico publicado en 2017

Computer-assisted engineering of the synthetic pathway for biodegradation of a toxic persistent pollutant.

artículo científico publicado en 2013

Deciphering the Structural Basis of High Thermostability of Dehalogenase from Psychrophilic Bacterium Marinobacter sp. ELB17

scientific article published on 28 October 2019

Different Structural Origins of the Enantioselectivity of Haloalkane Dehalogenases toward Linear β-Haloalkanes: Open-Solvated versus Occluded-Desolvated Active Sites.

artículo científico publicado en 2017

Discovery of Novel Haloalkane Dehalogenase Inhibitors.

artículo científico publicado en 2016

Dynamics, a Powerful Component of Current and Future in Silico Approaches for Protein Design and Engineering

artículo científico publicado en 2020

Engineering enzyme stability and resistance to an organic cosolvent by modification of residues in the access tunnel

artículo científico publicado en 2013

Enzyme Tunnels and Gates As Relevant Targets in Drug Design.

artículo científico publicado en 2016

Expansion of access tunnels and active-site cavities influence activity of haloalkane dehalogenases in organic cosolvents

artículo científico publicado en 2013

FireProt: Energy- and Evolution-Based Computational Design of Thermostable Multiple-Point Mutants

artículo científico publicado en 2015

FireProt: web server for automated design of thermostable proteins

artículo científico publicado en 2017

Fructose 1-phosphate is the one and only physiological effector of the Cra (FruR) regulator of Pseudomonas putida.

artículo científico publicado en 2014

HotSpot Wizard 2.0: automated design of site-specific mutations and smart libraries in protein engineering

artículo científico publicado en 2016

Impact of the access tunnel engineering on catalysis is strictly ligand-specific.

artículo científico publicado en 2018

Interaction of organic solvents with protein structures at protein-solvent interface

artículo científico publicado en 2012

Maximizing the efficiency of multienzyme process by stoichiometry optimization.

artículo científico publicado en 2014

Mechanism-based discovery of novel substrates of haloalkane dehalogenases using in silico screening

artículo científico publicado en 2014

Molecular Gating of an Engineered Enzyme Captured in Real Time

artículo científico publicado en 2018

PredictSNP2: A Unified Platform for Accurately Evaluating SNP Effects by Exploiting the Different Characteristics of Variants in Distinct Genomic Regions.

artículo científico publicado en 2016

PredictSNP: robust and accurate consensus classifier for prediction of disease-related mutations

artículo científico publicado en 2014

Site-Specific Analysis of Protein Hydration Based on Unnatural Amino Acid Fluorescence

artículo científico publicado en 2015

Software tools for identification, visualization and analysis of protein tunnels and channels.

artículo científico

Structural and functional analysis of a novel haloalkane dehalogenase with two halide-binding sites

artículo científico publicado en 2014

Substrate specificity of haloalkane dehalogenases.

artículo científico publicado en 2011

The effect of a unique halide-stabilizing residue on the catalytic properties of haloalkane dehalogenase DatA from Agrobacterium tumefaciens C58.

artículo científico publicado en 2013

Tools and data services registry: a community effort to document bioinformatics resources

artículo científico publicado en 2016

Toxic effects of nine polycyclic aromatic compounds on Enchytraeus crypticus in artificial soil in relation to their properties.

artículo científico publicado en 2011

Wedelolactone induces growth of breast cancer cells by stimulation of estrogen receptor signalling.

artículo científico publicado en 2015

Lista de obras de Jan Brezovsky

Ancestral Haloalkane Dehalogenases Show Robustness and Unique Substrate Specificity.

Are time-dependent fluorescence shifts at the tunnel mouth of haloalkane dehalogenase enzymes dependent on the choice of the chromophore?

CAVER 3.0: a tool for the analysis of transport pathways in dynamic protein structures

CAVER Analyst 1.0: graphic tool for interactive visualization and analysis of tunnels and channels in protein structures.

CAVER Analyst 2.0: analysis and visualization of channels and tunnels in protein structures and molecular dynamics trajectories

CAVER: Algorithms for Analyzing Dynamics of Tunnels in Macromolecules

Catalytic Cycle of Haloalkane Dehalogenases Toward Unnatural Substrates Explored by Computational Modeling

Computational tools for designing and engineering biocatalysts

Computational tools for designing smart libraries.

Computer-Assisted Engineering of Hyperstable Fibroblast Growth Factor 2.

Computer-assisted engineering of the synthetic pathway for biodegradation of a toxic persistent pollutant.

Deciphering the Structural Basis of High Thermostability of Dehalogenase from Psychrophilic Bacterium Marinobacter sp. ELB17

Different Structural Origins of the Enantioselectivity of Haloalkane Dehalogenases toward Linear β-Haloalkanes: Open-Solvated versus Occluded-Desolvated Active Sites.

Discovery of Novel Haloalkane Dehalogenase Inhibitors.

Dynamics, a Powerful Component of Current and Future in Silico Approaches for Protein Design and Engineering

Engineering enzyme stability and resistance to an organic cosolvent by modification of residues in the access tunnel

Enzyme Tunnels and Gates As Relevant Targets in Drug Design.

Expansion of access tunnels and active-site cavities influence activity of haloalkane dehalogenases in organic cosolvents

FireProt: Energy- and Evolution-Based Computational Design of Thermostable Multiple-Point Mutants

FireProt: web server for automated design of thermostable proteins

Fructose 1-phosphate is the one and only physiological effector of the Cra (FruR) regulator of Pseudomonas putida.

HotSpot Wizard 2.0: automated design of site-specific mutations and smart libraries in protein engineering

Impact of the access tunnel engineering on catalysis is strictly ligand-specific.

Interaction of organic solvents with protein structures at protein-solvent interface

Maximizing the efficiency of multienzyme process by stoichiometry optimization.

Mechanism-based discovery of novel substrates of haloalkane dehalogenases using in silico screening

Molecular Gating of an Engineered Enzyme Captured in Real Time

PredictSNP2: A Unified Platform for Accurately Evaluating SNP Effects by Exploiting the Different Characteristics of Variants in Distinct Genomic Regions.

PredictSNP: robust and accurate consensus classifier for prediction of disease-related mutations

Site-Specific Analysis of Protein Hydration Based on Unnatural Amino Acid Fluorescence

Software tools for identification, visualization and analysis of protein tunnels and channels.

Structural and functional analysis of a novel haloalkane dehalogenase with two halide-binding sites

Substrate specificity of haloalkane dehalogenases.

The effect of a unique halide-stabilizing residue on the catalytic properties of haloalkane dehalogenase DatA from Agrobacterium tumefaciens C58.

Tools and data services registry: a community effort to document bioinformatics resources

Toxic effects of nine polycyclic aromatic compounds on Enchytraeus crypticus in artificial soil in relation to their properties.

Wedelolactone induces growth of breast cancer cells by stimulation of estrogen receptor signalling.