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Lista de obras de Robert Daniel Beauchamp

A conditionally replicating adenovirus targeted to tumor cells through activated RAS/P-MAPK-selective mRNA stabilization.

artículo científico publicado en 2003

A network-based gene expression signature informs prognosis and treatment for colorectal cancer patients

artículo científico publicado el 23 de julio de 2012

A phase I study of concurrent 9-nitro-20(s)-camptothecin (9NC/Orathecin) and radiation therapy in the treatment of locally advanced adenocarcinoma of the pancreas

artículo científico publicado en 2005

A phase I study of vitamin E, 5-fluorouracil and leucovorin for advanced malignancies

artículo científico publicado en 2001

A specific inhibitor of TGF-beta receptor kinase, SB-431542, as a potent antitumor agent for human cancers.

artículo científico publicado en 2005

Adenoma-like adenocarcinoma: a subtype of colorectal carcinoma with good prognosis, deceptive appearance on biopsy and frequent KRAS mutation.

artículo científico publicado en 2015

Claudin-1 regulates intestinal epithelial homeostasis through the modulation of Notch-signalling.

artículo científico publicado en 2013

Claudin-2 expression increases tumorigenicity of colon cancer cells: role of epidermal growth factor receptor activation.

artículo científico publicado en 2011

Claudin-7 expression induces mesenchymal to epithelial transformation (MET) to inhibit colon tumorigenesis.

artículo científico publicado en 2014

Colon epithelial cell TGFβ signaling modulates the expression of tight junction proteins and barrier function in mice

artículo científico publicado en 2021

Coordinate regulation of cyclooxygenase-2 and TGF-beta1 in replication error-positive colon cancer and azoxymethane-induced rat colonic tumors

scientific article published on 01 February 1999

Cyclin D3 is essential for intestinal epithelial cell proliferation

artículo científico publicado en 2002

Cyclooxygenase-2 alters transforming growth factor-beta 1 response during intestinal tumorigenesis

artículo científico publicado en 1999

Deciphering genomic alterations in colorectal cancer through transcriptional subtype-based network analysis

artículo científico publicado en 2013

Differential effects of sodium butyrate and hexamethylene bisacetamide on growth and secretion of cultured human endocrine tumor cells

scientific article published on 01 April 1991

Dysregulation of E-cadherin by oncogenic Ras in intestinal epithelial cells is blocked by inhibiting MAP kinase

artículo científico publicado en 2003

E-cadherin is regulated by the transcriptional repressor SLUG during Ras-mediated transformation of intestinal epithelial cells

scientific journal article

Elevated ALCAM shedding in colorectal cancer correlates with poor patient outcome.

artículo científico publicado en 2013

Enhanced tumor formation in cyclin D1 x transforming growth factor beta1 double transgenic mice with characterization by magnetic resonance imaging

artículo científico publicado en 2004

Experimentally derived metastasis gene expression profile predicts recurrence and death in patients with colon cancer.

artículo científico publicado en 2009

Fibrogenesis in pancreatic cancer is a dynamic process regulated by macrophage-stellate cell interaction.

scientific article published on 17 February 2014

Four jointed box 1 promotes angiogenesis and is associated with poor patient survival in colorectal carcinoma

artículo científico publicado en 2013

HDAC inhibitors regulate claudin-1 expression in colon cancer cells through modulation of mRNA stability.

artículo científico publicado en 2009

Identification and isolation of candidate human colonic clonogenic cells based on cell surface integrin expression

artículo científico publicado en 2002

Identification and optimization of small molecules that restore E-cadherin expression and reduce invasion in colorectal carcinoma cells.

artículo científico publicado en 2011

Identification of early intestinal neoplasia protein biomarkers using laser capture microdissection and MALDI MS

artículo científico publicado en 2009

Induction of cyclooxygenase-2 and invasiveness by transforming growth factor-beta(1) in immortalized mouse colonocytes expressing oncogenic Ras.

artículo científico publicado en 2002

Induction of cyclooxygenase-2 by activated Ha-ras oncogene in Rat-1 fibroblasts and the role of mitogen-activated protein kinase pathway

artículo científico publicado en 1998

Inhibition of pRb phosphorylation and cell cycle progression by an antennapedia-p16(INK4A) fusion peptide in pancreatic cancer cells

artículo científico publicado en 2000

Intestinal transformation results in transforming growth factor-beta-dependent alteration in tumor cell-cell matrix interactions.

artículo científico publicado en 2003

Kaiso directs the transcriptional corepressor MTG16 to the Kaiso binding site in target promoters

artículo científico publicado en 2012

Linking patient outcome to high throughput protein expression data identifies novel regulators of colorectal adenocarcinoma aggressiveness

artículo científico publicado en 2015

Lymphatic mapping and sentinel lymphadenectomy after preoperative therapy for stage II and III breast cancer

scientific article published on 01 July 2003

Neoadjuvant concurrent paclitaxel and radiation in stage II/III breast cancer

artículo científico publicado en 2006

Nuclear factor of activated T-cell activity is associated with metastatic capacity in colon cancer

artículo científico publicado en 2014

Nuclear translocation of beta-catenin in hereditary and carcinogen-induced intestinal adenomas.

artículo científico publicado en 1998

Oncogenic Ras and transforming growth factor-beta synergistically regulate AU-rich element-containing mRNAs during epithelial to mesenchymal transition.

artículo científico publicado en 2008

Oncogenic Ras dominates overexpression of E-cadherin in malignant transformation of intestinal epithelial cells

artículo científico publicado en 2004

Oncogenic Ras-mediated cell growth arrest and apoptosis are associated with increased ubiquitin-dependent cyclin D1 degradation.

artículo científico publicado en 2000

Oncogenic function of a novel WD-domain protein, STRAP, in human carcinogenesis.

artículo científico publicado en 2006

Over-expression of cyclin D1 regulates Cdk4 protein synthesis.

artículo científico publicado en 2003

Phase I trial of Orzel (UFT plus leucovorin), cisplatin, and radiotherapy in the treatment of potentially resectable esophageal cancer

artículo científico publicado en 2005

Phase II study of preoperative paclitaxel/cisplatin with radiotherapy in locally advanced esophageal cancer

artículo científico publicado en 2006

Potentiation of apomorphine and D-amphetamine effects by naloxone

scientific article published on 01 February 1981

Presidential address: evolution

scientific article published on 01 August 2000

Prognostic gene expression signature associated with two molecularly distinct subtypes of colorectal cancer

artículo científico publicado en 2011

Regulation of cyclooxygenase-2 expression by the translational silencer TIA-1.

artículo científico publicado en 2003

Regulation of metastasis in colorectal adenocarcinoma: a collision between development and tumor biology.

artículo científico publicado en 2008

Resident work hour limits and patient safety.

artículo científico publicado en 2005

Resistance to transforming growth factor-beta occurs in the presence of normal Smad activation

artículo científico publicado en 2002

Role of Smad proteins in the regulation of NF-kappaB by TGF-beta in colon cancer cells.

artículo científico publicado en 2005

Role of cholecystokinin in canine pancreatic exocrine response to bombesin stimulation

artículo científico publicado en 1987

Short-term caloric restriction augments age-related decreases in gastrin content and release

artículo científico publicado en 1996

Smad4 regulates claudin-1 expression in a transforming growth factor-beta-independent manner in colon cancer cells

artículo científico publicado en 2007

Smad4-dependent regulation of urokinase plasminogen activator secretion and RNA stability associated with invasiveness by autocrine and paracrine transforming growth factor-beta

artículo científico publicado en 2006

Smad4-mediated signaling inhibits intestinal neoplasia by inhibiting expression of β-catenin.

artículo científico publicado en 2011

Smad7 induces tumorigenicity by blocking TGF-beta-induced growth inhibition and apoptosis.

artículo científico publicado en 2005

Systemic alterations in ornithine decarboxylase activity caused by colon cancer in mice

scientific article published on 01 June 1991

The changing roles of a surgical department chair: adapting to a changing environment.

artículo científico publicado en 2005

The use of a multidisciplinary morbidity and mortality conference to incorporate ACGME general competencies

artículo científico publicado el 25 de marzo de 2011

Transformation of intestinal epithelial cells by chronic TGF-beta1 treatment results in downregulation of the type II TGF-beta receptor and induction of cyclooxygenase-2.

artículo científico publicado en 1999

Transforming growth factor-beta inhibits rat intestinal cell growth by regulating cell cycle specific gene expression

artículo científico publicado en 1994

Unexpected growth-stimulatory effect of somatostatin analogue on cultured human pancreatic carcinoid cells

artículo científico publicado en 1992

Urine PGE-M: A Metabolite of Prostaglandin E2 as a Potential Biomarker of Advanced Colorectal Neoplasia

artículo científico publicado en 2006

XIAP monoubiquitylates Groucho/TLE to promote canonical Wnt signaling

artículo científico publicado en 2012