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Lista de obras de Hans-Ulrich Schildhaus

A subset of gastrointestinal stromal tumors previously regarded as wild-type tumors carries somatic activating mutations in KIT exon 8 (p.D419del)

artículo científico publicado en 2013

Activated RET and ROS: two new driver mutations in lung adenocarcinoma

artículo científico publicado en 2013

Activating PDGFRA mutations in inflammatory fibroid polyps occur in exons 12, 14 and 18 and are associated with tumour localization

artículo científico publicado el 6 de marzo de 2012

Challenging dedifferentiated liposarcoma identified by MDM2-amplification, a report of two cases

artículo científico publicado en 2014

Chromogenic in situ hybridization is a reliable assay for detection of ALK rearrangements in adenocarcinomas of the lung

artículo científico publicado en 2013

Clear cell papillary renal cell carcinoma and renal angiomyoadenomatous tumor: two variants of a morphologic, immunohistochemical, and genetic distinct entity of renal cell carcinoma

artículo científico publicado en 2015

Clinicopathological Characteristics of RET Rearranged Lung Cancer in European Patients

artículo científico publicado en 2016

Clinicopathological and molecular features of a large cohort of gastrointestinal stromal tumors (GISTs) and review of the literature: BRAF mutations in KIT/PDGFRA wild-type GISTs are rare events

artículo científico publicado en 2017

Comparison of pre-analytical FFPE sample preparation methods and their impact on massively parallel sequencing in routine diagnostics

artículo científico publicado en 2014

Current Standard and Future Perspectives in the Treatment of Gastrointestinal Stromal Tumors

artículo científico publicado en 2017

Diagnostic red flags: steroid-treated malignant CNS lymphoma mimicking autoimmune inflammatory demyelination

artículo científico publicado en 2017

EGFR and erbB2 in malignant peripheral nerve sheath tumors and implications for targeted therapy

artículo científico publicado en 2008

FGFR1 amplifications in squamous cell carcinomas of the lung: diagnostic and therapeutic implications

artículo científico publicado en 2013

FGFR2 is overexpressed in myxoid liposarcoma and inhibition of FGFR signaling impairs tumor growth in vitro

artículo científico publicado en 2015

Fibroblast Growth Factor Receptor 1 and Related Ligands in Small-Cell Lung Cancer

artículo científico publicado en 2015

Fibroblast growth factor receptor 1 (FGFR1) amplification is a potential therapeutic target in small-cell lung cancer

artículo científico publicado el 26 de julio de 2013

HR23b expression is a potential predictive biomarker for HDAC inhibitor treatment in mesenchymal tumours and is associated with response to vorinostat

artículo científico publicado en 2016

Harmonized PD-L1 immunohistochemistry for pulmonary squamous-cell and adenocarcinomas

artículo científico publicado en 2016

Heterogeneity of KRAS Mutation Status in Rectal Cancer

artículo científico publicado en 2016

Heterogeneous mechanisms of primary and acquired resistance to third-generation EGFR inhibitors

artículo científico publicado en 2016

High-Throughput Profiling of Colorectal Cancer Liver Metastases Reveals Intra- and Inter-Patient Heterogeneity in the EGFR and WNT Pathways Associated with Clinical Outcome

artículo científico publicado en 2022

Impact of updated HER2 testing guidelines in breast cancer--re-evaluation of HERA trial fluorescence in situ hybridization data

artículo científico publicado en 2015

Influence of Biopsy Technique on Molecular Genetic Tumor Characterization in Non-Small Cell Lung Cancer-The Prospective, Randomized, Single-Blinded, Multicenter PROFILER Study Protocol

artículo científico publicado en 2020

Integrative genome analyses identify key somatic driver mutations of small-cell lung cancer

artículo científico publicado en 2012

Interlaboratory-concordance of PD-L1 immunohistochemistry for non-small cell lung cancer

artículo científico

KIT-Dependent and KIT-Independent Genomic Heterogeneity of Resistance in Gastrointestinal Stromal Tumors - TORC1/2 Inhibition as Salvage Strategy

artículo científico publicado en 2019

Lysine-specific demethylase 1 is highly expressed in solitary fibrous tumors, synovial sarcomas, rhabdomyosarcomas, desmoplastic small round cell tumors, and malignant peripheral nerve sheath tumors

artículo científico publicado en 2011

MET gene copy number alterations and expression of MET and hepatocyte growth factor are potential biomarkers in angiosarcomas and undifferentiated pleomorphic sarcomas

artículo científico publicado en 2015

MET-GRB2 Signaling-Associated Complexes Correlate with Oncogenic MET Signaling and Sensitivity to MET Kinase Inhibitors

artículo científico publicado en 2017

Massively parallel sequencing fails to detect minor resistant subclones in tissue samples prior to tyrosine kinase inhibitor therapy

artículo científico publicado en 2015

Molecular methods in the diagnosis of sarcoma

artículo científico publicado el 1 de febrero de 2011

Multicenter immunohistochemical ALK-testing of non-small-cell lung cancer shows high concordance after harmonization of techniques and interpretation criteria

artículo científico publicado en 2014

Mutation analysis of gastrointestinal stromal tumors: increasing significance for risk assessment and effective targeted therapy

artículo científico publicado en 2007

Ovarian-type epithelial tumours of the testis: immunohistochemical and molecular analysis of two serous borderline tumours of the testis

artículo científico publicado en 2015

Partial Response to First-Line Crizotinib in an Elderly Male Patient with ROS1 Translocation-Positive Lung Cancer

artículo científico publicado en 2016

Pitfalls in mutational testing and reporting of common KIT and PDGFRA mutations in gastrointestinal stromal tumors

artículo científico publicado en 2010

Polyclonal evolution of multiple secondary KIT mutations in gastrointestinal stromal tumors under treatment with imatinib mesylate

artículo científico publicado en 2006

Post-transcriptional dysregulation by miRNAs is implicated in the pathogenesis of gastrointestinal stromal tumor [GIST]

artículo científico publicado en 2013

ROS1 rearrangements in lung adenocarcinoma: prognostic impact, therapeutic options and genetic variability

artículo científico publicado en 2015

Residual tumor cells are unique cellular targets in glioblastoma

artículo científico publicado en 2010

Resistance to avapritinib in PDGFRA-driven GIST is caused by secondary mutations in the PDGFRA kinase domain

scientific article published on 24 September 2020

SRC inhibition represents a potential therapeutic strategy in liposarcoma

artículo científico publicado en 2015

Sensitive and specific detection of EML4-ALK rearrangements in non-small cell lung cancer (NSCLC) specimens by multiplex amplicon RNA massive parallel sequencing

artículo científico publicado en 2014

Single-cell analysis of mtDNA deletion levels in sporadic amyotrophic lateral sclerosis

artículo científico publicado en 2004

Soft tissue sarcoma: from molecular diagnosis to selection of treatment. Pathological diagnosis of soft tissue sarcoma amid molecular biology and targeted therapies

artículo científico publicado el 1 de octubre de 2010

Spindle cell embryonal rhabdomyosarcoma of the prostate in an adult patient - case report and review of clinicopathological features

artículo científico publicado en 2016

Squamous Cell Carcinoma of the Pancreas in a Patient with Germline BRCA2 Mutation-Response to Neoadjuvant Radiochemotherapy

artículo científico publicado en 2014

c-myc copy number gain is a powerful prognosticator of disease outcome in cervical dysplasia

artículo científico publicado en 2015

miRNA-221 and miRNA-222 induce apoptosis via the KIT/AKT signalling pathway in gastrointestinal stromal tumours

artículo científico publicado en 2015

qPCR in gastrointestinal stromal tumors: Evaluation of reference genes and expression analysis of KIT and the alternative receptor tyrosine kinases FLT3, CSF1-R, PDGFRB, MET and AXL.

artículo científico publicado en 2010

β‐Catenin (CTNNB1) mutations and clinicopathological features of mesenteric desmoid‐type fibromatosis

artículo científico publicado el 28 de septiembre de 2012