Lista de obras - Malin Flodström-Tullberg

A Coxsackievirus B vaccine protects against virus-induced diabetes in an experimental mouse model of type 1 diabetes

artículo científico publicado en 2017

A Link Between a Common Mutation in CFTR and Impaired Innate and Adaptive Viral Defence.

artículo científico publicado en 2017

A comparative study of the effect of UV and formalin inactivation on the stability and immunogenicity of a Coxsackievirus B1 vaccine

scientific article published on 27 August 2019

A critical role for inducible nitric oxide synthase in host survival following coxsackievirus B4 infection.

artículo científico publicado en 2001

A hexavalent Coxsackievirus B vaccine is highly immunogenic and has a strong protective capacity in mice and nonhuman primates

scientific article published on 06 May 2020

A novel rat CVB1-VP1 monoclonal antibody 3A6 detects a broad range of enteroviruses.

artículo científico publicado en 2018

A preclinical study on the efficacy and safety of a new vaccine against Coxsackievirus B1 reveals no risk for accelerated diabetes development in mouse models.

artículo científico publicado en 2014

Alloreactivity but Failure to Reject Human Islet Transplants by Humanized Balb/c/Rag2−/−gc−/−Mice

artículo científico publicado en 2010

An IFIH1 gene polymorphism associated with risk for autoimmunity regulates canonical antiviral defence pathways in Coxsackievirus infected human pancreatic islets

artículo científico publicado en 2016

Antibody Responses against Enterovirus Proteases are Potential Markers for an Acute Infection

scientific article published on 09 January 2020

Application of bioinformatics in probe design enables detection of enteroviruses on different taxonomic levels by advanced in situ hybridization technology

artículo científico publicado en 2015

B7-2 (CD86) controls the priming of autoreactive CD4 T cell response against pancreatic islets

article

Beta-cell specific expression of suppressor of cytokine signaling-1 (SOCS-1) delays islet allograft rejection by down-regulating Interferon Regulatory Factor-1 (IRF-1) signaling ⬇️

artículo científico publicado el 15 de abril de 2011

CFTR and Anoctamin 1 (ANO1) contribute to cAMP amplified exocytosis and insulin secretion in human and murine pancreatic beta-cells

artículo científico publicado en 2014

CFTR is involved in the regulation of glucagon secretion in human and rodent alpha cells

artículo científico publicado en 2017

Co-transplantation of stromal cells interferes with the rejection of allogeneic islet grafts

artículo científico publicado en 2008

Composition and functionality of the intrahepatic innate lymphoid cell-compartment in human nonfibrotic and fibrotic livers

artículo científico publicado en 2017

Coxsackievirus B Persistence Modifies the Proteome and the Secretome of Pancreatic Ductal Cells

artículo científico publicado en 2019

Coxsackievirus counters the host innate immune response by blocking type III interferon expression.

artículo científico publicado en 2016

Cystic fibrosis bronchial epithelial cells have impaired ability to activate vitamin D.

artículo científico publicado en 2016

Cytokines activate the nuclear factor kappa B (NF-kappa B) and induce nitric oxide production in human pancreatic islets

article

Defective exocytosis and processing of insulin in a cystic fibrosis mouse model

scientific article published on 01 February 2019

Defining the proteolytic landscape during enterovirus infection

scientific article published on 30 September 2020

Depletion of IL-2 receptor β-positive cells protects from diabetes in non-obese diabetic mice.

artículo científico publicado en 2015

Detection of enterovirus in the islet cells of patients with type 1 diabetes: what do we learn from immunohistochemistry? Reply to Hansson SF, Korsgren S, Pontén F et al [letter].

artículo científico publicado en 2014

Diabetogenic potential of human pathogens uncovered in experimentally permissive beta-cells.

artículo científico publicado en 2003

Differences in suppressor of cytokine signaling-1 (SOCS-1) expressing islet allograft destruction in normal BALB/c and spontaneously-diabetic NOD recipient mice.

artículo científico publicado en 2005

Distinct phenotype and function of NK cells in the pancreas of nonobese diabetic mice.

artículo científico publicado en 2010

Ebselen and cytokine-induced nitric oxide synthase expression in insulin-producing cells.

artículo científico publicado en 1996

Enteroviral proteases: structure, host interactions and pathogenicity.

artículo científico publicado en 2016

Enterovirus Exposure Uniquely Discriminates Type 1 Diabetes Patients with a Homozygous from a Heterozygous Melanoma Differentiation-Associated Protein 5/Interferon Induced with Helicase C Domain 1 A946T Genotype

artículo científico publicado en 2016

Evaluation of the fidelity of immunolabelling obtained with clone 5D8/1, a monoclonal antibody directed against the enteroviral capsid protein, VP1, in human pancreas.

artículo científico publicado en 2013

Expression of Intestinal and Lung Alkaline Sphingomyelinase and Neutral Ceramidase in Cystic Fibrosis F508del Transgenic Mice

scientific article published on 01 November 2008

Expression of the citrulline-nitric oxide cycle in rodent and human pancreatic beta-cells: induction of argininosuccinate synthetase by cytokines

scientific article published on 01 August 1995

Expression patterns of NKG2A, KIR, and CD57 define a process of CD56dim NK-cell differentiation uncoupled from NK-cell education

article

Formalin treatment increases the stability and immunogenicity of coxsackievirus B1 VLP vaccine

artículo científico publicado en 2019

Genetic and Environmental Interaction in Type 1 Diabetes: a Relationship Between Genetic Risk Alleles and Molecular Traits of Enterovirus Infection?

artículo científico publicado en 2019

Immunology in the clinic review series; focus on type 1 diabetes and viruses: the innate immune response to enteroviruses and its possible role in regulating type 1 diabetes.

artículo científico

Induction of an antiviral state and attenuated coxsackievirus replication in type III interferon-treated primary human pancreatic islets

artículo científico publicado en 2013

Interferons induce an antiviral state in human pancreatic islet cells

artículo científico publicado en 2007

Interleukin 1beta increases arginine accumulation and activates the citrulline-NO cycle in rat pancreatic beta cells

artículo científico publicado en 1999

Large enteroviral vaccination studies to prevent type 1 diabetes should be well founded and rely on scientific evidence. Reply to Skog O, Klingel K, Roivainen M et al [letter]

scientific article published on 23 April 2019

Loss of parity between IL-2 and IL-21 in the NOD Idd3 locus

scholarly article

Mechanisms of Defective Glucose-Induced Insulin Release in Human Pancreatic Islets Transplanted to Diabetic Nude Mice1 ⬇️

artículo científico publicado el 1 de agosto de 1997

Natural killer cells in human autoimmunity

artículo científico publicado en 2009

New Coxsackievirus 2Apro and 3Cpro protease antibodies for virus detection and discovery of pathogenic mechanisms.

artículo científico publicado en 2018

Novel role for matricellular proteins in the regulation of islet β cell survival: the effect of SPARC on survival, proliferation, and signaling

artículo científico publicado en 2014

Optimized production and purification of Coxsackievirus B1 vaccine and its preclinical evaluation in a mouse model.

artículo científico publicado en 2017

Previous maternal infection protects offspring from enterovirus infection and prevents experimental diabetes development in mice.

artículo científico publicado en 2013

Protection against type 1 diabetes upon Coxsackievirus B4 infection and iNKT-cell stimulation: role of suppressive macrophages

artículo científico publicado en 2013

Pyrrolidine dithiocarbamate prevents IL-1-induced nitric oxide synthase mRNA, but not superoxide dismutase mRNA, in insulin producing cells.

artículo científico publicado en 1995

RNase L and double-stranded RNA-dependent protein kinase exert complementary roles in islet cell defense during coxsackievirus infection.

artículo científico publicado en 2005

Rationale for enteroviral vaccination and antiviral therapies in human type 1 diabetes

scientific article published on 23 January 2019

Recent acquisitions on the genetic basis of autoimmune disease

artículo científico publicado en 2008

Role of the citrulline-nitric oxide cycle in the functional response of adult human and rodent pancreatic islets to cytokines

article

SOCS2 deletion protects against hepatic steatosis but worsens insulin resistance in high-fat-diet-fed mice

artículo científico publicado en 2012

Severely Impaired Control of Bacterial Infections in a Patient With Cystic Fibrosis Defective in Mucosal-Associated Invariant T Cells.

artículo científico publicado en 2018

Short-term CFTR inhibition reduces islet area in C57BL/6 mice

artículo científico publicado en 2019

Strong attraction may be dangerous: parameters for the development of long term commitment.

artículo científico publicado en 2004

Structural Insight into CVB3-VLP Non-Adjuvanted Vaccine

artículo científico publicado en 2020

Target cell defense prevents the development of diabetes after viral infection.

artículo científico publicado en 2002

Target cell expression of suppressor of cytokine signaling-1 prevents diabetes in the NOD mouse.

artículo científico publicado en 2003

The TheraCyte™ Device Protects against Islet Allograft Rejection in Immunized Hosts

artículo científico publicado en 2012

The natural killer cell -- friend or foe in autoimmune disease?

artículo científico publicado en 2002

The stromal cell-derived factor-1alpha/CXCR4 ligand-receptor axis is critical for progenitor survival and migration in the pancreas ⬇️

artículo científico publicado en 2003

The target cell response to cytokines governs the autoreactive T cell repertoire in the pancreas of NOD mice.

artículo científico publicado en 2008

The target tissue in autoimmunity--an influential niche

artículo científico publicado en 2007

Type III interferons are expressed by Coxsackievirus-infected human primary hepatocytes and regulate hepatocyte permissiveness to infection.

artículo científico publicado en 2014

Viral infections: their elusive role in regulating susceptibility to autoimmune disease

artículo científico publicado en 2003

Vitamin D treatment modulates immune activation in cystic fibrosis.

artículo científico publicado en 2017

Lista de obras de Malin Flodström-Tullberg

A Coxsackievirus B vaccine protects against virus-induced diabetes in an experimental mouse model of type 1 diabetes

A Link Between a Common Mutation in CFTR and Impaired Innate and Adaptive Viral Defence.

A comparative study of the effect of UV and formalin inactivation on the stability and immunogenicity of a Coxsackievirus B1 vaccine

A critical role for inducible nitric oxide synthase in host survival following coxsackievirus B4 infection.

A hexavalent Coxsackievirus B vaccine is highly immunogenic and has a strong protective capacity in mice and nonhuman primates

A novel rat CVB1-VP1 monoclonal antibody 3A6 detects a broad range of enteroviruses.

A preclinical study on the efficacy and safety of a new vaccine against Coxsackievirus B1 reveals no risk for accelerated diabetes development in mouse models.

Alloreactivity but Failure to Reject Human Islet Transplants by Humanized Balb/c/Rag2−/−gc−/−Mice

An IFIH1 gene polymorphism associated with risk for autoimmunity regulates canonical antiviral defence pathways in Coxsackievirus infected human pancreatic islets

Antibody Responses against Enterovirus Proteases are Potential Markers for an Acute Infection

Application of bioinformatics in probe design enables detection of enteroviruses on different taxonomic levels by advanced in situ hybridization technology

B7-2 (CD86) controls the priming of autoreactive CD4 T cell response against pancreatic islets

Beta-cell specific expression of suppressor of cytokine signaling-1 (SOCS-1) delays islet allograft rejection by down-regulating Interferon Regulatory Factor-1 (IRF-1) signaling ⬇️

CFTR and Anoctamin 1 (ANO1) contribute to cAMP amplified exocytosis and insulin secretion in human and murine pancreatic beta-cells

CFTR is involved in the regulation of glucagon secretion in human and rodent alpha cells

Co-transplantation of stromal cells interferes with the rejection of allogeneic islet grafts

Composition and functionality of the intrahepatic innate lymphoid cell-compartment in human nonfibrotic and fibrotic livers

Coxsackievirus B Persistence Modifies the Proteome and the Secretome of Pancreatic Ductal Cells

Coxsackievirus counters the host innate immune response by blocking type III interferon expression.

Cystic fibrosis bronchial epithelial cells have impaired ability to activate vitamin D.

Cytokines activate the nuclear factor kappa B (NF-kappa B) and induce nitric oxide production in human pancreatic islets

Defective exocytosis and processing of insulin in a cystic fibrosis mouse model

Defining the proteolytic landscape during enterovirus infection

Depletion of IL-2 receptor β-positive cells protects from diabetes in non-obese diabetic mice.

Detection of enterovirus in the islet cells of patients with type 1 diabetes: what do we learn from immunohistochemistry? Reply to Hansson SF, Korsgren S, Pontén F et al [letter].

Diabetogenic potential of human pathogens uncovered in experimentally permissive beta-cells.

Differences in suppressor of cytokine signaling-1 (SOCS-1) expressing islet allograft destruction in normal BALB/c and spontaneously-diabetic NOD recipient mice.

Distinct phenotype and function of NK cells in the pancreas of nonobese diabetic mice.

Ebselen and cytokine-induced nitric oxide synthase expression in insulin-producing cells.

Enteroviral proteases: structure, host interactions and pathogenicity.

Enterovirus Exposure Uniquely Discriminates Type 1 Diabetes Patients with a Homozygous from a Heterozygous Melanoma Differentiation-Associated Protein 5/Interferon Induced with Helicase C Domain 1 A946T Genotype

Evaluation of the fidelity of immunolabelling obtained with clone 5D8/1, a monoclonal antibody directed against the enteroviral capsid protein, VP1, in human pancreas.

Expression of Intestinal and Lung Alkaline Sphingomyelinase and Neutral Ceramidase in Cystic Fibrosis F508del Transgenic Mice

Expression of the citrulline-nitric oxide cycle in rodent and human pancreatic beta-cells: induction of argininosuccinate synthetase by cytokines

Expression patterns of NKG2A, KIR, and CD57 define a process of CD56dim NK-cell differentiation uncoupled from NK-cell education

Formalin treatment increases the stability and immunogenicity of coxsackievirus B1 VLP vaccine

Genetic and Environmental Interaction in Type 1 Diabetes: a Relationship Between Genetic Risk Alleles and Molecular Traits of Enterovirus Infection?

Immunology in the clinic review series; focus on type 1 diabetes and viruses: the innate immune response to enteroviruses and its possible role in regulating type 1 diabetes.

Induction of an antiviral state and attenuated coxsackievirus replication in type III interferon-treated primary human pancreatic islets

Interferons induce an antiviral state in human pancreatic islet cells

Interleukin 1beta increases arginine accumulation and activates the citrulline-NO cycle in rat pancreatic beta cells

Large enteroviral vaccination studies to prevent type 1 diabetes should be well founded and rely on scientific evidence. Reply to Skog O, Klingel K, Roivainen M et al [letter]

Loss of parity between IL-2 and IL-21 in the NOD Idd3 locus

Mechanisms of Defective Glucose-Induced Insulin Release in Human Pancreatic Islets Transplanted to Diabetic Nude Mice1 ⬇️

Natural killer cells in human autoimmunity

New Coxsackievirus 2Apro and 3Cpro protease antibodies for virus detection and discovery of pathogenic mechanisms.

Novel role for matricellular proteins in the regulation of islet β cell survival: the effect of SPARC on survival, proliferation, and signaling

Optimized production and purification of Coxsackievirus B1 vaccine and its preclinical evaluation in a mouse model.

Previous maternal infection protects offspring from enterovirus infection and prevents experimental diabetes development in mice.

Protection against type 1 diabetes upon Coxsackievirus B4 infection and iNKT-cell stimulation: role of suppressive macrophages

Pyrrolidine dithiocarbamate prevents IL-1-induced nitric oxide synthase mRNA, but not superoxide dismutase mRNA, in insulin producing cells.

RNase L and double-stranded RNA-dependent protein kinase exert complementary roles in islet cell defense during coxsackievirus infection.

Rationale for enteroviral vaccination and antiviral therapies in human type 1 diabetes

Recent acquisitions on the genetic basis of autoimmune disease

Role of the citrulline-nitric oxide cycle in the functional response of adult human and rodent pancreatic islets to cytokines

SOCS2 deletion protects against hepatic steatosis but worsens insulin resistance in high-fat-diet-fed mice

Severely Impaired Control of Bacterial Infections in a Patient With Cystic Fibrosis Defective in Mucosal-Associated Invariant T Cells.

Short-term CFTR inhibition reduces islet area in C57BL/6 mice

Strong attraction may be dangerous: parameters for the development of long term commitment.

Structural Insight into CVB3-VLP Non-Adjuvanted Vaccine

Target cell defense prevents the development of diabetes after viral infection.

Target cell expression of suppressor of cytokine signaling-1 prevents diabetes in the NOD mouse.

The TheraCyte™ Device Protects against Islet Allograft Rejection in Immunized Hosts

The natural killer cell -- friend or foe in autoimmune disease?

The stromal cell-derived factor-1alpha/CXCR4 ligand-receptor axis is critical for progenitor survival and migration in the pancreas ⬇️

The target cell response to cytokines governs the autoreactive T cell repertoire in the pancreas of NOD mice.

The target tissue in autoimmunity--an influential niche

Type III interferons are expressed by Coxsackievirus-infected human primary hepatocytes and regulate hepatocyte permissiveness to infection.

Viral infections: their elusive role in regulating susceptibility to autoimmune disease

Vitamin D treatment modulates immune activation in cystic fibrosis.