Lista de obras - Brendan J. Jenkins - Dominio Público Uruguay

A cell type-specific constitutive point mutant of the common beta-subunit of the human granulocyte-macrophage colony-stimulating factor (GM-CSF), interleukin (IL)-3, and IL-5 receptors requires the GM-CSF receptor alpha-subunit for activation

artículo científico publicado en 1999

ADAM17 selectively activates the IL-6 trans-signaling/ERK MAPK axis in KRAS-addicted lung cancer

artículo científico publicado en 2019

Critical and independent role for SOCS3 in either myeloid or T cells in resistance to Mycobacterium tuberculosis

artículo científico publicado en 2013

Deregulated Stat3 signaling dissociates pulmonary inflammation from emphysema in gp130 mutant mice

artículo científico publicado en 2012

Differential involvement of gp130 signalling pathways in modulating tobacco carcinogen-induced lung tumourigenesis.

artículo científico publicado en 2014

Differential regulation of gastric tumor growth by cytokines that signal exclusively through the coreceptor gp130.

artículo científico publicado en 2005

Differential role of MyD88 and Mal/TIRAP in TLR2-mediated gastric tumourigenesis.

artículo científico publicado en 2013

Endoscopic ultrasound-guided fine-needle aspirate-derived preclinical pancreatic cancer models reveal panitumumab sensitivity in KRAS wild-type tumors.

artículo científico publicado en 2017

Exacerbated inflammatory arthritis in response to hyperactive gp130 signalling is independent of IL-17A ⬇️

artículo científico publicado el 26 de julio de 2013

Functional expression cloning reveals proapoptotic role for protein phosphatase 4

scientific article published on 01 September 2003

Gastric cancer development in mice lacking the SHP2 binding site on the IL-6 family co-receptor gp130.

artículo científico publicado en 2004

Hematopoietic abnormalities in mice deficient in gp130-mediated STAT signaling

artículo científico publicado en 2002

Hyperactivation of Stat3 in gp130 mutant mice promotes gastric hyperproliferation and desensitizes TGF-beta signaling.

artículo científico publicado en 2005

Hyperactive gp130/STAT3-driven gastric tumourigenesis promotes submucosal tertiary lymphoid structure development. ⬇️

artículo científico publicado en 2018

IL-6 trans-signaling modulates TLR4-dependent inflammatory responses via STAT3.

artículo científico publicado en 2010

IL-6 trans-signaling via STAT3 directs T cell infiltration in acute inflammation.

artículo científico publicado en 2005

IL-6/Stat3-driven pulmonary inflammation, but not emphysema, is dependent on interleukin-17A in mice.

artículo científico publicado en 2014

IL6 Trans-signaling Promotes KRAS-Driven Lung Carcinogenesis.

artículo científico publicado en 2016

Imbalanced gp130 signalling in ApoE-deficient mice protects against atherosclerosis

artículo científico publicado en 2014

In vivo evidence that RBM5 is a tumour suppressor in the lung

artículo científico publicado en 2017

Inflammation modulates the expression of the intestinal mucins MUC2 and MUC4 in gastric tumors.

artículo científico publicado en 2010

Innate cellular sources of interleukin-17A regulate macrophage accumulation in cigarette- smoke-induced lung inflammation in mice.

artículo científico publicado en 2015

Interacting residues in the extracellular region of the common beta subunit of the human granulocyte-macrophage colony-stimulating factor, interleukin (IL)-3, and IL-5 receptors involved in constitutive activation.

artículo científico publicado en 1996

Interleukin-27 inhibits ectopic lymphoid-like structure development in early inflammatory arthritis.

artículo científico publicado en 2015

Interleukin-6 promotes pulmonary emphysema associated with apoptosis in mice.

artículo científico publicado en 2011

Interleukin-6 signaling drives fibrosis in unresolved inflammation

scientific article published on 09 January 2014

Investigating the Role of Toll-Like Receptors in Mouse Models of Gastric Cancer

artículo científico publicado en 2016

Isolation and characterization of a sheep cysteine-rich cuticle keratin pseudogene

artículo científico publicado el 1 de enero de 1992

LPS hypersensitivity of gp130 mutant mice is independent of elevated haemopoietic TLR4 signaling.

artículo científico publicado en 2011

Myeloid Differentiation Factor 88 Signaling in Bone Marrow-Derived Cells Promotes Gastric Tumorigenesis by Generation of Inflammatory Microenvironment.

artículo científico publicado en 2016

Naive and activated T cells display differential responsiveness to TL1A that affects Th17 generation, maintenance, and proliferation.

artículo científico publicado en 2010

Nucleotide oligomerization domain 1 enhances IFN-γ signaling in gastric epithelial cells during Helicobacter pylori infection and exacerbates disease severity.

artículo científico publicado en 2013

Oncogenic dependency on STAT3 serine phosphorylation in KRAS mutant lung cancer

artículo científico publicado en 2021

Pathologic consequences of STAT3 hyperactivation by IL-6 and IL-11 during hematopoiesis and lymphopoiesis

artículo científico publicado en 2006

Potential efficacy of interleukin-1β inhibition in lung cancer

artículo científico publicado en 2017

Rab8a interacts directly with PI3Kγ to modulate TLR4-driven PI3K and mTOR signalling

artículo científico publicado en 2014

STAT1 plays a role in TLR signal transduction and inflammatory responses.

artículo científico publicado en 2014

STAT3 activation regulates growth, inflammation, and vascularization in a mouse model of gastric tumorigenesis.

artículo científico publicado en 2006

STAT3 and STAT1 mediate IL-11-dependent and inflammation-associated gastric tumorigenesis in gp130 receptor mutant mice.

artículo científico publicado en 2008

STAT3-driven upregulation of TLR2 promotes gastric tumorigenesis independent of tumor inflammation.

artículo científico publicado en 2012

Suppressor of cytokine signaling 3 regulates CD8 T-cell proliferation by inhibition of interleukins 6 and 27.

artículo científico publicado en 2007

The molecular pathogenesis of STAT3-driven gastric tumourigenesis in mice is independent of IL-17.

artículo científico publicado en 2011

The threshold of gp130-dependent STAT3 signaling is critical for normal regulation of hematopoiesis

scientific article published on 13 January 2005

Toll-like receptor 2 regulates metabolic reprogramming in gastric cancer via superoxide dismutase 2

artículo científico publicado en 2019

Transcriptional regulation of pattern recognition receptors by Jak/STAT signaling, and the implications for disease pathogenesis

artículo científico publicado en 2014

Tying the knot between cytokine and toll-like receptor signaling in gastrointestinal tract cancers.

artículo científico

Lista de obras de Brendan J. Jenkins

A cell type-specific constitutive point mutant of the common beta-subunit of the human granulocyte-macrophage colony-stimulating factor (GM-CSF), interleukin (IL)-3, and IL-5 receptors requires the GM-CSF receptor alpha-subunit for activation

ADAM17 selectively activates the IL-6 trans-signaling/ERK MAPK axis in KRAS-addicted lung cancer

Critical and independent role for SOCS3 in either myeloid or T cells in resistance to Mycobacterium tuberculosis

Deregulated Stat3 signaling dissociates pulmonary inflammation from emphysema in gp130 mutant mice

Differential involvement of gp130 signalling pathways in modulating tobacco carcinogen-induced lung tumourigenesis.

Differential regulation of gastric tumor growth by cytokines that signal exclusively through the coreceptor gp130.

Differential role of MyD88 and Mal/TIRAP in TLR2-mediated gastric tumourigenesis.

Endoscopic ultrasound-guided fine-needle aspirate-derived preclinical pancreatic cancer models reveal panitumumab sensitivity in KRAS wild-type tumors.

Exacerbated inflammatory arthritis in response to hyperactive gp130 signalling is independent of IL-17A ⬇️

Functional expression cloning reveals proapoptotic role for protein phosphatase 4

Gastric cancer development in mice lacking the SHP2 binding site on the IL-6 family co-receptor gp130.

Hematopoietic abnormalities in mice deficient in gp130-mediated STAT signaling

Hyperactivation of Stat3 in gp130 mutant mice promotes gastric hyperproliferation and desensitizes TGF-beta signaling.

Hyperactive gp130/STAT3-driven gastric tumourigenesis promotes submucosal tertiary lymphoid structure development. ⬇️

IL-6 trans-signaling modulates TLR4-dependent inflammatory responses via STAT3.

IL-6 trans-signaling via STAT3 directs T cell infiltration in acute inflammation.

IL-6/Stat3-driven pulmonary inflammation, but not emphysema, is dependent on interleukin-17A in mice.

IL6 Trans-signaling Promotes KRAS-Driven Lung Carcinogenesis.

Imbalanced gp130 signalling in ApoE-deficient mice protects against atherosclerosis

In vivo evidence that RBM5 is a tumour suppressor in the lung

Inflammation modulates the expression of the intestinal mucins MUC2 and MUC4 in gastric tumors.

Innate cellular sources of interleukin-17A regulate macrophage accumulation in cigarette- smoke-induced lung inflammation in mice.

Interacting residues in the extracellular region of the common beta subunit of the human granulocyte-macrophage colony-stimulating factor, interleukin (IL)-3, and IL-5 receptors involved in constitutive activation.

Interleukin-27 inhibits ectopic lymphoid-like structure development in early inflammatory arthritis.

Interleukin-6 promotes pulmonary emphysema associated with apoptosis in mice.

Interleukin-6 signaling drives fibrosis in unresolved inflammation

Investigating the Role of Toll-Like Receptors in Mouse Models of Gastric Cancer

Isolation and characterization of a sheep cysteine-rich cuticle keratin pseudogene

LPS hypersensitivity of gp130 mutant mice is independent of elevated haemopoietic TLR4 signaling.

Myeloid Differentiation Factor 88 Signaling in Bone Marrow-Derived Cells Promotes Gastric Tumorigenesis by Generation of Inflammatory Microenvironment.

Naive and activated T cells display differential responsiveness to TL1A that affects Th17 generation, maintenance, and proliferation.

Nucleotide oligomerization domain 1 enhances IFN-γ signaling in gastric epithelial cells during Helicobacter pylori infection and exacerbates disease severity.

Oncogenic dependency on STAT3 serine phosphorylation in KRAS mutant lung cancer

Pathologic consequences of STAT3 hyperactivation by IL-6 and IL-11 during hematopoiesis and lymphopoiesis

Potential efficacy of interleukin-1β inhibition in lung cancer

Rab8a interacts directly with PI3Kγ to modulate TLR4-driven PI3K and mTOR signalling

STAT1 plays a role in TLR signal transduction and inflammatory responses.

STAT3 activation regulates growth, inflammation, and vascularization in a mouse model of gastric tumorigenesis.

STAT3 and STAT1 mediate IL-11-dependent and inflammation-associated gastric tumorigenesis in gp130 receptor mutant mice.

STAT3-driven upregulation of TLR2 promotes gastric tumorigenesis independent of tumor inflammation.

Suppressor of cytokine signaling 3 regulates CD8 T-cell proliferation by inhibition of interleukins 6 and 27.

The molecular pathogenesis of STAT3-driven gastric tumourigenesis in mice is independent of IL-17.

The threshold of gp130-dependent STAT3 signaling is critical for normal regulation of hematopoiesis

Toll-like receptor 2 regulates metabolic reprogramming in gastric cancer via superoxide dismutase 2

Transcriptional regulation of pattern recognition receptors by Jak/STAT signaling, and the implications for disease pathogenesis

Tying the knot between cytokine and toll-like receptor signaling in gastrointestinal tract cancers.