Lista de obras - Sandra K. Weller - Dominio Público Uruguay

A mutation in the C-terminal putative Zn2+ finger motif of UL52 severely affects the biochemical activities of the HSV-1 helicase-primase subcomplex.

artículo científico publicado en 1999

A mutation in the human herpes simplex virus type 1 UL52 zinc finger motif results in defective primase activity but can recruit viral polymerase and support viral replication efficiently.

artículo científico publicado en 2007

A putative leucine zipper within the herpes simplex virus type 1 UL6 protein is required for portal ring formation

artículo científico publicado en 2007

ATR and ATRIP are recruited to herpes simplex virus type 1 replication compartments even though ATR signaling is disabled.

artículo científico publicado en 2010

An Intrinsically Disordered Region of the DNA Repair Protein Nbs1 Is a Species-Specific Barrier to Herpes Simplex Virus 1 in Primates

artículo científico publicado en 2016

Beta interferon and gamma interferon synergize to block viral DNA and virion synthesis in herpes simplex virus-infected cells.

artículo científico publicado en 2005

Biochemical analyses of mutations in the HSV-1 helicase-primase that alter ATP hydrolysis, DNA unwinding, and coupling between hydrolysis and unwinding

artículo científico publicado en 1997

Catalysis of strand exchange by the HSV-1 UL12 and ICP8 proteins: potent ICP8 recombinase activity is revealed upon resection of dsDNA substrate by nuclease.

artículo científico publicado en 2004

DNA Damage Kills Bacterial Spores and Cells Exposed to 222-Nanometer UV Radiation

artículo científico publicado en 2020

DNA Mismatch Repair Proteins Are Required for Efficient Herpes Simplex Virus 1 Replication ⬇️

artículo científico publicado el 28 de septiembre de 2011

DNA binding activity of the herpes simplex virus type 1 origin binding protein, UL9, can be modulated by sequences in the N terminus: correlation between transdominance and DNA binding.

artículo científico publicado en 2006

Direct interaction between the N- and C-terminal portions of the herpes simplex virus type 1 origin binding protein UL9 implies the formation of a head-to-tail dimer.

artículo científico publicado en 2007

Disulfide Bond Formation in the Herpes Simplex Virus 1 UL6 Protein Is Required for Portal Ring Formation and Genome Encapsidation ⬇️

artículo científico publicado el 18 de mayo de 2011

Disulfide bond formation contributes to herpes simplex virus capsid stability and retention of pentons.

artículo científico publicado en 2011

Efficient herpes simplex virus 1 replication requires cellular ATR pathway proteins

artículo científico publicado en 2012

Enhanced phosphorylation of transcription factor sp1 in response to herpes simplex virus type 1 infection is dependent on the ataxia telangiectasia-mutated protein

artículo científico publicado en 2007

Functional Conservations of the Alkaline Nuclease of Herpes Simplex Type 1 and Human Cytomegalovirus

artículo científico publicado en 1998

Genetic analysis of the UL 15 gene locus for the putative terminase of herpes simplex virus type 1.

artículo científico publicado en 1998

HSV cheats the executioner

artículo científico publicado en 2015

HSV-1 protein expression using recombinant baculoviruses

artículo científico publicado en 2014

HSV-I and the cellular DNA damage response.

artículo científico

Herpes Simplex Viruses: Mechanisms of DNA Replication ⬇️

artículo científico publicado el 1 de septiembre de 2012

Herpes simplex virus 1 ICP8 mutant lacking annealing activity is deficient for viral DNA replication

scientific article published on 31 December 2018

Herpes simplex virus 1 alkaline nuclease is required for efficient egress of capsids from the nucleus

artículo científico publicado en 1993

Herpes simplex virus DNA cleavage and packaging proteins associate with the procapsid prior to its maturation.

artículo científico publicado en 2001

Herpes simplex virus eliminates host mitochondrial DNA.

artículo científico publicado en 2006

Herpes simplex virus reorganizes the cellular DNA repair and protein quality control machinery.

artículo científico publicado en 2010

Herpes simplex virus type 1 DNA polymerase requires the mammalian chaperone hsp90 for proper localization to the nucleus

artículo científico publicado en 2005

Herpes simplex virus type 1 helicase-primase: DNA binding and consequent protein oligomerization and primase activation

artículo científico publicado en 2010

Herpes simplex virus type 1 immediate-early protein ICP22 is required for VICE domain formation during productive viral infection

artículo científico publicado en 2009

Herpes simplex virus type 1 mutants for the origin-binding protein induce DNA amplification in the absence of viral replication

artículo científico publicado en 1990

Herpes simplex virus type 1 single strand DNA binding protein and helicase/primase complex disable cellular ATR signaling

artículo científico publicado en 2013

Herpes simplex virus type 1 single-strand DNA binding protein ICP8 enhances the nuclease activity of the UL12 alkaline nuclease by increasing its processivity

artículo científico publicado en 2005

Herpes simplex virus type I disrupts the ATR-dependent DNA-damage response during lytic infection

artículo científico publicado en 2006

Identification of rep-associated factors in herpes simplex virus type 1-induced adeno-associated virus type 2 replication compartments.

artículo científico publicado en 2010

Inhibition of the herpes simplex virus type 1 DNA polymerase induces hyperphosphorylation of replication protein A and its accumulation at S-phase-specific sites of DNA damage during infection.

artículo científico publicado en 2005

Interactions of herpes simplex virus type 1 with ND10 and recruitment of PML to replication compartments.

artículo científico publicado en 2001

Intracellular localization of the herpes simplex virus type-1 origin binding protein, UL9.

artículo científico publicado en 1996

Isolation of herpes simplex virus procapsids from cells infected with a protease-deficient mutant virus.

artículo científico publicado en 2000

Mutations in the putative zinc-binding motif of UL52 demonstrate a complex interdependence between the UL5 and UL52 subunits of the human herpes simplex virus type 1 helicase/primase complex.

artículo científico publicado en 2005

Nuclear sequestration of cellular chaperone and proteasomal machinery during herpes simplex virus type 1 infection

artículo científico publicado en 2004

Physical interaction between the herpes simplex virus type 1 exonuclease, UL12, and the DNA double-strand break-sensing MRN complex

artículo científico publicado en 2010

Recombination promoted by DNA viruses: phage λ to herpes simplex virus.

artículo científico publicado en 2014

Recruitment of cellular recombination and repair proteins to sites of herpes simplex virus type 1 DNA replication is dependent on the composition of viral proteins within prereplicative sites and correlates with the induction of the DNA damage respo

artículo científico publicado en 2004

Recruitment of polymerase to herpes simplex virus type 1 replication foci in cells expressing mutant primase (UL52) proteins.

artículo científico publicado en 2003

Residues within the conserved helicase motifs of UL9, the origin-binding protein of herpes simplex virus-1, are essential for helicase activity but not for dimerization or origin binding activity

artículo científico publicado en 2000

Sequence and mapping analyses of the herpes simplex virus DNA polymerase gene predict a C-terminal substrate binding domain.

artículo científico publicado en 1985

Structural Characterization of Interaction between Human Ubiquitin-specific Protease 7 and Immediate-Early Protein ICP0 of Herpes Simplex Virus-1.

artículo científico publicado en 2015

Structure of the herpes simplex virus 1 genome: manipulation of nicks and gaps can abrogate infectivity and alter the cellular DNA damage response.

artículo científico publicado en 2014

The DNA helicase-primase complex as a target for herpes viral infection

artículo científico publicado en 2013

The Exonuclease Activity of HSV-1 UL12 Is Required forin VivoFunction

artículo científico publicado en 1998

The HSV-1 exonuclease, UL12, stimulates recombination by a single strand annealing mechanism

scientific journal article

The Herpes Simplex Virus 1 Immediate Early Protein ICP22 Is a Functional Mimic of a Cellular J Protein

scientific article published on 31 January 2020

The Rep protein of adeno-associated virus type 2 interacts with single-stranded DNA-binding proteins that enhance viral replication

artículo científico publicado en 2004

The UL12.5 gene product of herpes simplex virus type 1 exhibits nuclease and strand exchange activities but does not localize to the nucleus

artículo científico publicado en 2004

The UL5 and UL52 subunits of the herpes simplex virus type 1 helicase-primase subcomplex exhibit a complex interdependence for DNA binding.

artículo científico

The UL6 gene product forms the portal for entry of DNA into the herpes simplex virus capsid.

artículo científico publicado en 2001

The exonuclease activity of HSV-1 UL12 is required for the production of viral DNA that can be packaged to produce infectious virus

artículo científico publicado en 2017

The harms of promoting the lab leak hypothesis for SARS-CoV-2 origins without evidence

The herpes simplex virus type 1 UL6 protein is essential for cleavage and packaging but not for genomic inversion

artículo científico publicado en 1996

The herpes simplex virus type 1 transactivator ICPO mediates aberrant intracellular localization of the viral helicase/primase complex subunits

artículo científico publicado en 1996

The product of a 1.9-kb mRNA which overlaps the HSV-1 alkaline nuclease gene (UL12) cannot relieve the growth defects of a null mutant

artículo científico publicado en 1996

The product of the UL12.5 gene of herpes simplex virus type 1 is not essential for lytic viral growth and is not specifically associated with capsids.

artículo científico publicado en 2002

The putative herpes simplex virus 1 chaperone protein UL32 modulates disulfide bond formation during infection

artículo científico publicado en 2014

The role of DNA recombination in herpes simplex virus DNA replication.

artículo científico publicado en 2003

The two helicases of herpes simplex virus type 1 (HSV-1).

artículo científico publicado en 2006

Two-Metal Ion-Dependent Enzymes as Potential Antiviral Targets in Human Herpesviruses

artículo científico publicado en 2022

Lista de obras de Sandra K. Weller

A mutation in the C-terminal putative Zn2+ finger motif of UL52 severely affects the biochemical activities of the HSV-1 helicase-primase subcomplex.

A mutation in the human herpes simplex virus type 1 UL52 zinc finger motif results in defective primase activity but can recruit viral polymerase and support viral replication efficiently.

A putative leucine zipper within the herpes simplex virus type 1 UL6 protein is required for portal ring formation

ATR and ATRIP are recruited to herpes simplex virus type 1 replication compartments even though ATR signaling is disabled.

An Intrinsically Disordered Region of the DNA Repair Protein Nbs1 Is a Species-Specific Barrier to Herpes Simplex Virus 1 in Primates

Beta interferon and gamma interferon synergize to block viral DNA and virion synthesis in herpes simplex virus-infected cells.

Biochemical analyses of mutations in the HSV-1 helicase-primase that alter ATP hydrolysis, DNA unwinding, and coupling between hydrolysis and unwinding

Catalysis of strand exchange by the HSV-1 UL12 and ICP8 proteins: potent ICP8 recombinase activity is revealed upon resection of dsDNA substrate by nuclease.

DNA Damage Kills Bacterial Spores and Cells Exposed to 222-Nanometer UV Radiation

DNA Mismatch Repair Proteins Are Required for Efficient Herpes Simplex Virus 1 Replication ⬇️

DNA binding activity of the herpes simplex virus type 1 origin binding protein, UL9, can be modulated by sequences in the N terminus: correlation between transdominance and DNA binding.

Direct interaction between the N- and C-terminal portions of the herpes simplex virus type 1 origin binding protein UL9 implies the formation of a head-to-tail dimer.

Disulfide Bond Formation in the Herpes Simplex Virus 1 UL6 Protein Is Required for Portal Ring Formation and Genome Encapsidation ⬇️

Disulfide bond formation contributes to herpes simplex virus capsid stability and retention of pentons.

Efficient herpes simplex virus 1 replication requires cellular ATR pathway proteins

Enhanced phosphorylation of transcription factor sp1 in response to herpes simplex virus type 1 infection is dependent on the ataxia telangiectasia-mutated protein

Functional Conservations of the Alkaline Nuclease of Herpes Simplex Type 1 and Human Cytomegalovirus

Genetic analysis of the UL 15 gene locus for the putative terminase of herpes simplex virus type 1.

HSV cheats the executioner

HSV-1 protein expression using recombinant baculoviruses

HSV-I and the cellular DNA damage response.

Herpes Simplex Viruses: Mechanisms of DNA Replication ⬇️

Herpes simplex virus 1 ICP8 mutant lacking annealing activity is deficient for viral DNA replication

Herpes simplex virus 1 alkaline nuclease is required for efficient egress of capsids from the nucleus

Herpes simplex virus DNA cleavage and packaging proteins associate with the procapsid prior to its maturation.

Herpes simplex virus eliminates host mitochondrial DNA.

Herpes simplex virus reorganizes the cellular DNA repair and protein quality control machinery.

Herpes simplex virus type 1 DNA polymerase requires the mammalian chaperone hsp90 for proper localization to the nucleus

Herpes simplex virus type 1 helicase-primase: DNA binding and consequent protein oligomerization and primase activation

Herpes simplex virus type 1 immediate-early protein ICP22 is required for VICE domain formation during productive viral infection

Herpes simplex virus type 1 mutants for the origin-binding protein induce DNA amplification in the absence of viral replication

Herpes simplex virus type 1 single strand DNA binding protein and helicase/primase complex disable cellular ATR signaling

Herpes simplex virus type 1 single-strand DNA binding protein ICP8 enhances the nuclease activity of the UL12 alkaline nuclease by increasing its processivity

Herpes simplex virus type I disrupts the ATR-dependent DNA-damage response during lytic infection

Identification of rep-associated factors in herpes simplex virus type 1-induced adeno-associated virus type 2 replication compartments.

Inhibition of the herpes simplex virus type 1 DNA polymerase induces hyperphosphorylation of replication protein A and its accumulation at S-phase-specific sites of DNA damage during infection.

Interactions of herpes simplex virus type 1 with ND10 and recruitment of PML to replication compartments.

Intracellular localization of the herpes simplex virus type-1 origin binding protein, UL9.

Isolation of herpes simplex virus procapsids from cells infected with a protease-deficient mutant virus.

Mutations in the putative zinc-binding motif of UL52 demonstrate a complex interdependence between the UL5 and UL52 subunits of the human herpes simplex virus type 1 helicase/primase complex.

Nuclear sequestration of cellular chaperone and proteasomal machinery during herpes simplex virus type 1 infection

Physical interaction between the herpes simplex virus type 1 exonuclease, UL12, and the DNA double-strand break-sensing MRN complex

Recombination promoted by DNA viruses: phage λ to herpes simplex virus.

Recruitment of cellular recombination and repair proteins to sites of herpes simplex virus type 1 DNA replication is dependent on the composition of viral proteins within prereplicative sites and correlates with the induction of the DNA damage respo

Recruitment of polymerase to herpes simplex virus type 1 replication foci in cells expressing mutant primase (UL52) proteins.

Residues within the conserved helicase motifs of UL9, the origin-binding protein of herpes simplex virus-1, are essential for helicase activity but not for dimerization or origin binding activity

Sequence and mapping analyses of the herpes simplex virus DNA polymerase gene predict a C-terminal substrate binding domain.

Structural Characterization of Interaction between Human Ubiquitin-specific Protease 7 and Immediate-Early Protein ICP0 of Herpes Simplex Virus-1.

Structure of the herpes simplex virus 1 genome: manipulation of nicks and gaps can abrogate infectivity and alter the cellular DNA damage response.

The DNA helicase-primase complex as a target for herpes viral infection

The Exonuclease Activity of HSV-1 UL12 Is Required forin VivoFunction

The HSV-1 exonuclease, UL12, stimulates recombination by a single strand annealing mechanism

The Herpes Simplex Virus 1 Immediate Early Protein ICP22 Is a Functional Mimic of a Cellular J Protein

The Rep protein of adeno-associated virus type 2 interacts with single-stranded DNA-binding proteins that enhance viral replication

The UL12.5 gene product of herpes simplex virus type 1 exhibits nuclease and strand exchange activities but does not localize to the nucleus

The UL5 and UL52 subunits of the herpes simplex virus type 1 helicase-primase subcomplex exhibit a complex interdependence for DNA binding.

The UL6 gene product forms the portal for entry of DNA into the herpes simplex virus capsid.

The exonuclease activity of HSV-1 UL12 is required for the production of viral DNA that can be packaged to produce infectious virus

The harms of promoting the lab leak hypothesis for SARS-CoV-2 origins without evidence

The herpes simplex virus type 1 UL6 protein is essential for cleavage and packaging but not for genomic inversion

The herpes simplex virus type 1 transactivator ICPO mediates aberrant intracellular localization of the viral helicase/primase complex subunits

The product of a 1.9-kb mRNA which overlaps the HSV-1 alkaline nuclease gene (UL12) cannot relieve the growth defects of a null mutant

The product of the UL12.5 gene of herpes simplex virus type 1 is not essential for lytic viral growth and is not specifically associated with capsids.

The putative herpes simplex virus 1 chaperone protein UL32 modulates disulfide bond formation during infection

The role of DNA recombination in herpes simplex virus DNA replication.

The two helicases of herpes simplex virus type 1 (HSV-1).

Two-Metal Ion-Dependent Enzymes as Potential Antiviral Targets in Human Herpesviruses