Lista de obras - Thomas Karn - Dominio Público Uruguay

"Stem cell like" breast cancers-a model for the identification of new prognostic/predictive markers in endocrine responsive breast cancer exemplified by Plexin B1

scientific article published on 15 April 2008

A Comprehensive Analysis of Human Gene Expression Profiles Identifies Stromal Immunoglobulin C as a Compatible Prognostic Marker in Human Solid Tumors

article

A Small Hypoxia Signature Predicted pCR Response to Bevacizumab in the Neoadjuvant GeparQuinto Breast Cancer Trial

artículo científico publicado en 2020

A clinically relevant gene signature in triple negative and basal-like breast cancer

artículo científico publicado en 2011

Acid ceramidase (AC)--a key enzyme of sphingolipid metabolism--correlates with better prognosis in epithelial ovarian cancer

artículo científico publicado en 2013

Acid ceramidase 1 expression correlates with a better prognosis in ER-positive breast cancer

artículo científico publicado en 2009

Acid ceramidase is associated with an improved prognosis in both DCIS and invasive breast cancer.

artículo científico publicado en 2014

Androgen receptor expression and response to chemotherapy in breast cancer patients treated in the neoadjuvant TECHNO and PREPARE trial

scientific article published on 15 November 2019

Androgen receptor expression is a predictive marker in chemotherapy-treated patients with endocrine receptor-positive primary breast cancers.

artículo científico publicado en 2013

Association Between Genomic Metrics and Immune Infiltration in Triple-Negative Breast Cancer

artículo científico publicado en 2017

Breast Cancer Proteomics - Differences in Protein Expression between Estrogen Receptor-Positive and -Negative Tumors Identified by Tandem Mass Tag Technology

artículo científico publicado en 2010

C-KIT expression in ductal carcinoma in situ of the breast: co-expression with HER-2/neu

artículo científico publicado en 2006

CD73 is associated with poor prognosis in high-grade serous ovarian cancer

artículo científico publicado en 2015

Catheter-related Complications of Subcutaneous Implantable Venous Access Devices in Breast Cancer Patients

artículo científico publicado en 2018

Characterization of WNT7A expression in human endometrium and endometriotic lesions

artículo científico publicado en 2007

Characterization of the human CSK locus

scientific article published on 01 May 1993

Claudin-1 expression in cervical cancer.

artículo científico publicado en 2017

Claudin-1 is linked to presence of implants and micropapillary pattern in serous borderline epithelial tumours of the ovary

artículo científico publicado en 2018

Clinical Relevance of Collagen Protein Degradation Markers C3M and C4M in the Serum of Breast Cancer Patients Treated with Neoadjuvant Therapy in the GeparQuinto Trial

artículo científico publicado en 2019

Clinical relevance of the putative stem cell marker p63 in breast cancer

artículo científico publicado en 2009

Control of dataset bias in combined Affymetrix cohorts of triple negative breast cancer

artículo científico publicado en 2014

Controversies concerning the use of neoadjuvant systemic therapy for primary breast cancer

artículo científico publicado en 2012

Correction: The lipid-transfer protein Nir2 enhances epithelial-mesenchymal transition and facilitates breast cancer metastasis (doi:10.1242/jcs.155721)

artículo científico publicado en 2019

Data-driven derivation of cutoffs from a pool of 3,030 Affymetrix arrays to stratify distinct clinical types of breast cancer

artículo científico publicado en 2009

Differential effect on different immune subsets of neoadjuvant chemotherapy in patients with TNBC

artículo científico publicado en 2020

Differential expression of claudins in human endometrium and endometriosis

scientific article published on 01 August 2008

Differentially expressed genes of reprogrammed human pluripotent stem cells in breast cancer

artículo científico publicado en 2008

Dynamic classification using case-specific training cohorts outperforms static gene expression signatures in breast cancer.

artículo científico publicado en 2014

Evaluation of soluble carbonic anhydrase IX as predictive marker for efficacy of bevacizumab: A biomarker analysis from the geparquinto phase III neoadjuvant breast cancer trial

artículo científico publicado en 2019

Expression of membrane-type 5 matrix metalloproteinase in human endometrium and endometriosis

artículo científico publicado en 2007

Expression of secreted protein acidic and rich in cysteine (SPARC) in breast cancer and response to neoadjuvant chemotherapy.

artículo científico publicado en 2014

Fascin-1 expression as stratification marker in borderline epithelial tumours of the ovary

artículo científico publicado en 2015

Gene expression of ceramide kinase, galactosyl ceramide synthase and ganglioside GD3 synthase is associated with prognosis in breast cancer

artículo científico publicado en 2009

Gene expression of topoisomerase II alpha (TOP2A) by microarray analysis is highly prognostic in estrogen receptor (ER) positive breast cancer

artículo científico publicado en 2008

Gene expression profiles of breast cancer obtained from core cut biopsies before neoadjuvant docetaxel, adriamycin, and cyclophoshamide chemotherapy correlate with routine prognostic markers and could be used to identify predictive signatures

artículo científico publicado en 2006

Gene expression profiling of luminal B breast cancers reveals NHERF1 as a new marker of endocrine resistance

artículo científico publicado en 2011

Genomic predictor of residual risk of recurrence after adjuvant chemotherapy and endocrine therapy in high risk estrogen receptor-positive breast cancers.

artículo científico publicado en 2015

High-throughput gene expression and mutation profiling: current methods and future perspectives.

scientific article published on December 2013

Histotype-specific analysis of acid ceramidase expression in ovarian cancer

scientific article published on 02 January 2020

Homogeneous datasets of triple negative breast cancers enable the identification of novel prognostic and predictive signatures

artículo científico publicado en 2011

Human SAK related to the PLK/polo family of cell cycle kinases shows high mRNA expression in testis.

artículo científico publicado en 1997

Human and Xenopus mo15 messenger-RNA are highly conserved but show different patterns of expression in adult tissues ⬇️

artículo científico publicado el 1 de noviembre de 1994

Human leucocyte antigen class I in hormone receptor-positive, HER2-negative breast cancer: association with response and survival after neoadjuvant chemotherapy

scientific article published on 11 December 2019

IMP3 Expression in Borderline Tumors of the Ovary

artículo científico publicado en 2017

Identification and Validation of a Novel Biologics Target in Triple Negative Breast Cancer

scientific article published on 17 October 2019

Identification of preeclampsia by cDNA-gene expression profiling in human placentas and serum -- a pilot study

artículo científico publicado en 2006

Immune Gene Expression Is Associated with Genomic Aberrations in Breast Cancer

artículo científico publicado en 2017

Impact of re-excision of residual adjacent vulvar intraepithelial neoplasia (VIN III) and histological tumour-free margin (hTFM) on survival in primary squamous cell carcinoma of vulva

artículo científico publicado en 2018

Ki67 measured after neoadjuvant chemotherapy for primary breast cancer

artículo científico publicado en 2013

Loss of Plexin B1 is highly prognostic in low proliferating ER positive breast cancers--results of a large scale microarray analysis

scientific article published on 04 December 2008

Melanoma antigen family A identified by the bimodality index defines a subset of triple negative breast cancers as candidates for immune response augmentation

artículo científico publicado en 2011

Methylation of estrogen receptor beta promoter correlates with loss of ER-beta expression in mammary carcinoma and is an early indication marker in premalignant lesions

artículo científico publicado en 2005

Microarray analysis of altered sphingolipid metabolism reveals prognostic significance of sphingosine kinase 1 in breast cancer.

artículo científico publicado en 2007

Molecular Markers as Prognostic Factors in DCIS and Small Invasive Breast Cancers

artículo científico publicado en 2014

Mutational Diversity and Therapy Response in Breast Cancer: A Sequencing Analysis in the Neoadjuvant GeparSepto Trial

artículo científico publicado en 2019

Nef proteins of distinct HIV-1 or -2 isolates differ in their binding properties for HCK: isolation of a novel Nef binding factor with characteristics of an adaptor protein.

artículo científico publicado en 1998

New Strategies in Breast Cancer: Immunotherapy.

artículo científico publicado en 2016

OPG and PgR show similar cohort specific effects as prognostic factors in ER positive breast cancer

artículo científico publicado en 2014

Oncogenic alterations in primary human lung-tumors (review)

artículo científico publicado el 1 de enero de 1994

Outcome after neoadjuvant chemotherapy in estrogen receptor-positive and progesterone receptor-negative breast cancer patients: a pooled analysis of individual patient data from ten prospectively randomized controlled neoadjuvant trials

artículo científico publicado en 2017

PYK2 sustains endosomal-derived receptor signalling and enhances epithelial-to-mesenchymal transition.

artículo científico publicado en 2015

Poor outcome in estrogen receptor-positive breast cancers predicted by loss of plexin B1

artículo científico publicado en 2007

Predictive value of sphingosine kinase 1 expression in neoadjuvant treatment of breast cancer

artículo científico publicado en 2013

Prognostic evaluation of the B cell/IL-8 metagene in different intrinsic breast cancer subtypes

artículo científico publicado en 2012

Prognostic impact of fascin-1 (FSCN1) in epithelial ovarian cancer

artículo científico publicado en 2013

Prognostic impact of thymidine phosphorylase expression in breast cancer--comparison of microarray and immunohistochemical data

artículo científico publicado en 2009

Prognostic relevance of glucosylceramide synthase (GCS) expression in breast cancer

artículo científico publicado en 2008

Prognostic relevance of glycosylation-associated genes in breast cancer

artículo científico publicado en 2014

Proliferation and estrogen signaling can distinguish patients at risk for early versus late relapse among estrogen receptor positive breast cancers

artículo científico publicado en 2013

Quantitative analysis of the sHLA-G protein in seminal plasma

artículo científico publicado en 2019

Recommendations from an international consensus conference on the current status and future of neoadjuvant systemic therapy in primary breast cancer.

artículo científico

Relevance of cellular and serum carbonic anhydrase IX in primary breast cancer

artículo científico publicado en 2013

Relevance of tumour-infiltrating lymphocytes, PD-1 and PD-L1 in patients with high-risk, nodal-metastasised breast cancer of the German Adjuvant Intergroup Node-positive study

scientific article published on 07 May 2019

SATB1 gene expression and breast cancer prognosis ⬇️

artículo científico publicado el 25 de octubre de 2010

Specific microRNA signatures in exosomes of triple-negative and HER2-positive breast cancer patients undergoing neoadjuvant therapy within the GeparSixto trial

scientific article published on 10 October 2018

Structure, expression and chromosomal mapping of TKT from man and mouse: a new subclass of receptor tyrosine kinases with a factor VIII-like domain

artículo científico publicado en 1993

Subtype-Specific Metagene-Based Prediction of Outcome after Neoadjuvant and Adjuvant Treatment in Breast Cancer.

artículo científico publicado en 2015

Synthetic lethal combination targeting BET uncovered intrinsic susceptibility of TNBC to ferroptosis

scientific article published on 21 August 2020

T-cell metagene predicts a favorable prognosis in estrogen receptor-negative and HER2-positive breast cancers.

scientific article published on 09 March 2009

TFF3 Expression as Stratification Marker in Borderline Epithelial Tumors of the Ovary

artículo científico publicado en 2017

Targeting of PYK2 Synergizes with EGFR Antagonists in Basal-like TNBC and Circumvents HER3-Associated Resistance via the NEDD4-NDRG1 Axis

artículo científico publicado en 2016

The Influence of Host Factors on the Prognosis of Breast Cancer: Stroma and Immune Cell Components as Cancer Biomarkers

artículo científico

The lipid-transfer protein Nir2 enhances epithelial-mesenchymal transition and facilitates breast cancer metastasis

artículo científico publicado en 2014

The prognostic impact of age in different molecular subtypes of breast cancer

artículo científico publicado en 2015

The prognostic impact of age in patients with triple-negative breast cancer

artículo científico publicado en 2013

The role of genetic breast cancer susceptibility variants as prognostic factors

artículo científico publicado en 2012

Trefoil factor 3 expression in epithelial ovarian cancer exerts a minor effect on clinicopathological parameters.

artículo científico publicado en 2016

Tyrosine-614, the major autophosphorylation site of the receptor tyrosine kinase HEK2, functions as multi-docking site for SH2-domain mediated interactions

artículo científico publicado en 1998

Validity of the proliferation markers Ki67, TOP2A, and RacGAP1 in molecular subgroups of breast cancer

artículo científico publicado en 2012

Lista de obras de Thomas Karn

"Stem cell like" breast cancers-a model for the identification of new prognostic/predictive markers in endocrine responsive breast cancer exemplified by Plexin B1

A Comprehensive Analysis of Human Gene Expression Profiles Identifies Stromal Immunoglobulin C as a Compatible Prognostic Marker in Human Solid Tumors

A Small Hypoxia Signature Predicted pCR Response to Bevacizumab in the Neoadjuvant GeparQuinto Breast Cancer Trial

A clinically relevant gene signature in triple negative and basal-like breast cancer

Acid ceramidase (AC)--a key enzyme of sphingolipid metabolism--correlates with better prognosis in epithelial ovarian cancer

Acid ceramidase 1 expression correlates with a better prognosis in ER-positive breast cancer

Acid ceramidase is associated with an improved prognosis in both DCIS and invasive breast cancer.

Androgen receptor expression and response to chemotherapy in breast cancer patients treated in the neoadjuvant TECHNO and PREPARE trial

Androgen receptor expression is a predictive marker in chemotherapy-treated patients with endocrine receptor-positive primary breast cancers.

Association Between Genomic Metrics and Immune Infiltration in Triple-Negative Breast Cancer

Breast Cancer Proteomics - Differences in Protein Expression between Estrogen Receptor-Positive and -Negative Tumors Identified by Tandem Mass Tag Technology

C-KIT expression in ductal carcinoma in situ of the breast: co-expression with HER-2/neu

CD73 is associated with poor prognosis in high-grade serous ovarian cancer

Catheter-related Complications of Subcutaneous Implantable Venous Access Devices in Breast Cancer Patients

Characterization of WNT7A expression in human endometrium and endometriotic lesions

Characterization of the human CSK locus

Claudin-1 expression in cervical cancer.

Claudin-1 is linked to presence of implants and micropapillary pattern in serous borderline epithelial tumours of the ovary

Clinical Relevance of Collagen Protein Degradation Markers C3M and C4M in the Serum of Breast Cancer Patients Treated with Neoadjuvant Therapy in the GeparQuinto Trial

Clinical relevance of the putative stem cell marker p63 in breast cancer

Control of dataset bias in combined Affymetrix cohorts of triple negative breast cancer

Controversies concerning the use of neoadjuvant systemic therapy for primary breast cancer

Correction: The lipid-transfer protein Nir2 enhances epithelial-mesenchymal transition and facilitates breast cancer metastasis (doi:10.1242/jcs.155721)

Data-driven derivation of cutoffs from a pool of 3,030 Affymetrix arrays to stratify distinct clinical types of breast cancer

Differential effect on different immune subsets of neoadjuvant chemotherapy in patients with TNBC

Differential expression of claudins in human endometrium and endometriosis

Differentially expressed genes of reprogrammed human pluripotent stem cells in breast cancer

Dynamic classification using case-specific training cohorts outperforms static gene expression signatures in breast cancer.

Evaluation of soluble carbonic anhydrase IX as predictive marker for efficacy of bevacizumab: A biomarker analysis from the geparquinto phase III neoadjuvant breast cancer trial

Expression of membrane-type 5 matrix metalloproteinase in human endometrium and endometriosis

Expression of secreted protein acidic and rich in cysteine (SPARC) in breast cancer and response to neoadjuvant chemotherapy.

Fascin-1 expression as stratification marker in borderline epithelial tumours of the ovary

Gene expression of ceramide kinase, galactosyl ceramide synthase and ganglioside GD3 synthase is associated with prognosis in breast cancer

Gene expression of topoisomerase II alpha (TOP2A) by microarray analysis is highly prognostic in estrogen receptor (ER) positive breast cancer

Gene expression profiles of breast cancer obtained from core cut biopsies before neoadjuvant docetaxel, adriamycin, and cyclophoshamide chemotherapy correlate with routine prognostic markers and could be used to identify predictive signatures

Gene expression profiling of luminal B breast cancers reveals NHERF1 as a new marker of endocrine resistance

Genomic predictor of residual risk of recurrence after adjuvant chemotherapy and endocrine therapy in high risk estrogen receptor-positive breast cancers.

High-throughput gene expression and mutation profiling: current methods and future perspectives.

Histotype-specific analysis of acid ceramidase expression in ovarian cancer

Homogeneous datasets of triple negative breast cancers enable the identification of novel prognostic and predictive signatures

Human SAK related to the PLK/polo family of cell cycle kinases shows high mRNA expression in testis.

Human and Xenopus mo15 messenger-RNA are highly conserved but show different patterns of expression in adult tissues ⬇️

Human leucocyte antigen class I in hormone receptor-positive, HER2-negative breast cancer: association with response and survival after neoadjuvant chemotherapy

IMP3 Expression in Borderline Tumors of the Ovary

Identification and Validation of a Novel Biologics Target in Triple Negative Breast Cancer

Identification of preeclampsia by cDNA-gene expression profiling in human placentas and serum -- a pilot study

Immune Gene Expression Is Associated with Genomic Aberrations in Breast Cancer

Impact of re-excision of residual adjacent vulvar intraepithelial neoplasia (VIN III) and histological tumour-free margin (hTFM) on survival in primary squamous cell carcinoma of vulva

Ki67 measured after neoadjuvant chemotherapy for primary breast cancer

Loss of Plexin B1 is highly prognostic in low proliferating ER positive breast cancers--results of a large scale microarray analysis

Melanoma antigen family A identified by the bimodality index defines a subset of triple negative breast cancers as candidates for immune response augmentation

Methylation of estrogen receptor beta promoter correlates with loss of ER-beta expression in mammary carcinoma and is an early indication marker in premalignant lesions

Microarray analysis of altered sphingolipid metabolism reveals prognostic significance of sphingosine kinase 1 in breast cancer.

Molecular Markers as Prognostic Factors in DCIS and Small Invasive Breast Cancers

Mutational Diversity and Therapy Response in Breast Cancer: A Sequencing Analysis in the Neoadjuvant GeparSepto Trial

Nef proteins of distinct HIV-1 or -2 isolates differ in their binding properties for HCK: isolation of a novel Nef binding factor with characteristics of an adaptor protein.

New Strategies in Breast Cancer: Immunotherapy.

OPG and PgR show similar cohort specific effects as prognostic factors in ER positive breast cancer

Oncogenic alterations in primary human lung-tumors (review)

Outcome after neoadjuvant chemotherapy in estrogen receptor-positive and progesterone receptor-negative breast cancer patients: a pooled analysis of individual patient data from ten prospectively randomized controlled neoadjuvant trials

PYK2 sustains endosomal-derived receptor signalling and enhances epithelial-to-mesenchymal transition.

Poor outcome in estrogen receptor-positive breast cancers predicted by loss of plexin B1

Predictive value of sphingosine kinase 1 expression in neoadjuvant treatment of breast cancer

Prognostic evaluation of the B cell/IL-8 metagene in different intrinsic breast cancer subtypes

Prognostic impact of fascin-1 (FSCN1) in epithelial ovarian cancer

Prognostic impact of thymidine phosphorylase expression in breast cancer--comparison of microarray and immunohistochemical data

Prognostic relevance of glucosylceramide synthase (GCS) expression in breast cancer

Prognostic relevance of glycosylation-associated genes in breast cancer

Proliferation and estrogen signaling can distinguish patients at risk for early versus late relapse among estrogen receptor positive breast cancers

Quantitative analysis of the sHLA-G protein in seminal plasma

Recommendations from an international consensus conference on the current status and future of neoadjuvant systemic therapy in primary breast cancer.

Relevance of cellular and serum carbonic anhydrase IX in primary breast cancer

Relevance of tumour-infiltrating lymphocytes, PD-1 and PD-L1 in patients with high-risk, nodal-metastasised breast cancer of the German Adjuvant Intergroup Node-positive study

SATB1 gene expression and breast cancer prognosis ⬇️

Specific microRNA signatures in exosomes of triple-negative and HER2-positive breast cancer patients undergoing neoadjuvant therapy within the GeparSixto trial

Structure, expression and chromosomal mapping of TKT from man and mouse: a new subclass of receptor tyrosine kinases with a factor VIII-like domain

Subtype-Specific Metagene-Based Prediction of Outcome after Neoadjuvant and Adjuvant Treatment in Breast Cancer.

Synthetic lethal combination targeting BET uncovered intrinsic susceptibility of TNBC to ferroptosis

T-cell metagene predicts a favorable prognosis in estrogen receptor-negative and HER2-positive breast cancers.