Lista de obras - Antonio Rosato - Dominio Público Uruguay

A BARF1-specific mAb as a new immunotherapeutic tool for the management of EBV-related tumors

artículo científico publicado en 2017

A MicroRNA targeting dicer for metastasis control

artículo científico publicado en 2010

A Mutant-p53/Smad complex opposes p63 to empower TGFbeta-induced metastasis

artículo científico publicado en 2009

A Pin1/mutant p53 axis promotes aggressiveness in breast cancer

artículo científico publicado en 2011

A YAP camera for the biodistribution of 188Re conjugated with Hyaluronic-Acid in “in vivo” systems

A covalent PIN1 inhibitor selectively targets cancer cells by a dual mechanism of action.

artículo científico publicado en 2017

A human promyelocytic-like population is responsible for the immune suppression mediated by myeloid-derived suppressor cells.

artículo científico publicado en 2011

A large number of T lymphocytes recognize Moloney-murine leukemia virus-induced antigens, but a few mediate long-lasting tumor immunosurveillance.

artículo científico publicado en 2005

A non-covalent antibody complex for the delivery of anti-cancer drugs

scientific article published on 12 June 2019

A novel orally active water-soluble inhibitor of human glutathione transferase exerts a potent and selective antitumor activity against human melanoma xenografts

artículo científico publicado en 2015

A paclitaxel-hyaluronan bioconjugate targeting ovarian cancer affords a potent in vivo therapeutic activity

artículo científico publicado en 2008

A single-chain fragment against prostate specific membrane antigen as a tool to build theranostic reagents for prostate cancer.

artículo científico publicado en 2013

A site-selective hyaluronan-interferonα2a conjugate for the treatment of ovarian cancer

artículo científico publicado en 2016

Adoptive cell therapy against EBV-related malignancies: a survey of clinical results

scientific article published on 01 September 2008

Adoptive cell therapy of triple negative breast cancer with redirected cytokine-induced killer cells

scientific article published on 11 June 2020

Amniotic Fluid Stem Cells Restore the Muscle Cell Niche in a HSA-Cre, SmnF7/F7 Mouse Model

artículo científico publicado en 2012

Anti-L-selectin monoclonal antibody treatment in mice enhances tumor growth by preventing CTL sensitization in peripheral lymph nodes draining the tumor area

artículo científico publicado en 1996

Antitumour efficacy of lymphokine-activated killer cells loaded with ricin against experimentally induced lung metastases

artículo científico publicado en 1992

Autologous cellular vaccine overcomes cancer immunoediting in a mouse model of myeloma.

artículo científico publicado en 2015

Biodistribution imaging of a paclitaxel-hyaluronan bioconjugate.

artículo científico publicado en 2009

Biokinetic and dosimetric studies of 188Re-hyaluronic acid: a new radiopharmaceutical for treatment of hepatocellular carcinoma

artículo científico publicado en 2009

Broadening Specificity and Enhancing Cytotoxicity of Adoptive T Cells for Nasopharyngeal Carcinoma Immunotherapy.

artículo científico publicado en 2016

CD45 regulates apoptosis induced by extracellular adenosine triphosphate and cytotoxic T lymphocytes.

artículo científico publicado en 1996

CTL Response and Protection Against P815 Tumor Challenge in Mice Immunized with DNA Expressing the Tumor-Specific Antigen P815A

article

Cell-autonomous and cell non-autonomous downregulation of tumor suppressor DAB2IP by microRNA-149-3p promotes aggressiveness of cancer cells.

artículo científico publicado en 2018

Combination of sorafenib and everolimus impacts therapeutically on adrenocortical tumor models.

artículo científico publicado en 2012

Cytokines for the induction of antitumor effectors: The paradigm of Cytokine-Induced Killer (CIK) cells

artículo científico publicado en 2017

DNA immunization of mice against SIVmac239 Gag and Env using Rev-independent expression plasmids

artículo científico publicado en 1998

DNA-based vaccination against tumors expressing the P1A antigen

scientific article published on 01 September 1999

Delivery of methoxymorpholinyl doxorubicin by interleukin 2-activated NK cells: effect in mice bearing hepatic metastases

artículo científico publicado en 1999

Design, synthesis and evaluation of biotin decorated inulin-based polymeric micelles as long-circulating nanocarriers for targeted drug delivery.

artículo científico publicado en 2017

Diabetes-Associated Myelopoiesis Drives Stem Cell Mobilopathy Through an OSM-p66Shc Signaling Pathway

scientific article published on 01 April 2019

Differential down-modulation of HLA class I and II molecule expression on human tumor cell lines upon in vivo transfer.

artículo científico publicado en 2011

Differential effect on TCR:CD3 stimulation of a 90-kD glycoprotein (gp90/Mac-2BP), a member of the scavenger receptor cysteine-rich domain protein family

artículo científico publicado en 1998

Differential effects of angiostatin, endostatin and interferon-alpha(1) gene transfer on in vivo growth of human breast cancer cells.

artículo científico publicado en 2002

Drug and protein delivery by polymer conjugation

Drug conjugation to hyaluronan widens therapeutic indications for ovarian cancer

artículo científico publicado en 2015

Effect of antiadhesive agents on peritoneal carcinomatosis in an experimental model.

artículo científico publicado en 2003

Enhanced EGFR Targeting Activity of Plasmonic Nanostructures with Engineered GE11 Peptide.

artículo científico publicado en 2017

Exploiting the interplay between innate and adaptive immunity to improve immunotherapeutic strategies for Epstein-Barr-virus-driven disorders

artículo científico publicado en 2012

Expression of survivin, p53, and caspase 3 in Barrett's esophagus carcinogenesis

artículo científico publicado en 2006

Fast method for skeletal tissue gene expression analysis

artículo científico publicado en 2016

Fighting Viral Infections and Virus-Driven Tumors with Cytotoxic CD4+ T Cells

artículo científico publicado en 2017

Folic acid-conjugated europium complexes as luminescent probes for selective targeting of cancer cells

artículo científico publicado en 2015

Functional avidity-driven activation-induced cell death shapes CTL immunodominance

artículo científico publicado en 2014

Genome-wide association between YAP/TAZ/TEAD and AP-1 at enhancers drives oncogenic growth

artículo científico publicado en 2015

Glucocorticoid receptor signalling activates YAP in breast cancer

artículo científico publicado en 2017

Glutathione transferases as targets for cancer therapy.

scientific article published on September 2009

HMGA1 promotes metastatic processes in basal-like breast cancer regulating EMT and stemness.

artículo científico publicado en 2013

HYTAD1-p20: a new paclitaxel-hyaluronic acid hydrosoluble bioconjugate for treatment of superficial bladder cancer

artículo científico publicado en 2006

Human IgGs induce synthesis and secretion of IgGs and neonatal Fc receptor in human umbilical vein endothelial cells.

artículo científico publicado en 2016

Hyaluronic Acid as a Protein Polymeric Carrier: An Overview and a Report on Human Growth Hormone.

artículo científico

IGKV3 proteins as candidate "off-the-shelf" vaccines for kappa-light chain-restricted B-cell non-Hodgkin lymphomas.

artículo científico publicado en 2012

Identification of a HLA-A*0201-restricted immunogenic epitope from the universal tumor antigen DEPDC1.

artículo científico publicado en 2017

Identifying type Vicenza von Willebrand disease

scientific article published on 01 February 2006

Immunotherapeutic Strategies for Gastric Carcinoma: A Review of Preclinical and Clinical Recent Development.

artículo científico publicado en 2017

Immunotherapy for EBV-associated malignancies.

artículo científico publicado en 2011

Impact of γ-chain cytokines on EBV-specific T cell cultures.

artículo científico publicado en 2010

Improvement of diaphragmatic performance through orthotopic application of decellularized extracellular matrix patch

artículo científico publicado en 2015

In situ analysis of human menin in normal and neoplastic pancreatic tissues: evidence for differential expression in exocrine and endocrine cells

artículo científico publicado en 2003

In vitro hepatic conversion of the anticancer agent nemorubicin to its active metabolite PNU-159682 in mice, rats and dogs: a comparison with human liver microsomes

artículo científico publicado en 2008

In vivo fate of avidin-nucleic acid nanoassemblies as multifunctional diagnostic tools.

artículo científico publicado en 2013

Individual analysis of mice vaccinated against a weakly immunogenic self tumor-specific antigen reveals a correlation between CD8 T cell response and antitumor efficacy.

artículo científico publicado en 2003

Induction of Expandable Tissue-Specific Stem/Progenitor Cells through Transient Expression of YAP/TAZ.

artículo científico publicado en 2016

Inflammatory polyarthropathy and bone remodeling in HTLV-I Tax-transgenic mice.

artículo científico publicado en 1997

Inhibition of CTL-line lysis after gangliosides treatment

artículo científico publicado el 1 de septiembre de 1992

Inhibition of protein tyrosine phosphorylation prevents T-cell-mediated cytotoxicity

scientific article published on 01 December 1994

Internal radiation dose assessment of radiopharmaceuticals prepared with cyclotron-produced 99m Tc

artículo científico publicado en 2019

Low-Dose Paclitaxel Reduces S100A4 Nuclear Import to Inhibit Invasion and Hematogenous Metastasis of Cholangiocarcinoma.

artículo científico publicado en 2016

Mechanical cues control mutant p53 stability through a mevalonate-RhoA axis.

artículo científico publicado en 2017

Melanoma targeting with [99mTc(N)(PNP3)]-labeled α-melanocyte stimulating hormone peptide analogs: Effects of cyclization on the radiopharmaceutical properties.

artículo científico publicado en 2016

Membrane form of TNF alpha induces both cell lysis and apoptosis in susceptible target cells

artículo científico publicado en 1996

Metabolic control of YAP and TAZ by the mevalonate pathway.

artículo científico publicado en 2014

Mutant p53 reprograms TNF signaling in cancer cells through interaction with the tumor suppressor DAB2IP.

artículo científico publicado en 2014

Novel [99mTcIII(PS)2(Ln)] mixed-ligand compounds (PS = phosphino-thiolate; L = dithiocarbamate) useful in design and development of TcIII-based agents: synthesis, in vitro, and ex vivo biodistribution studies

scientific article published on 03 November 2014

Novel types of carborane-carrier hyaluronan derivatives via "click chemistry".

artículo científico publicado en 2008

Optical and multimodal peptide-based probes for in vivo molecular imaging.

artículo científico publicado en 2012

PSMA-specific CAR-engineered T cells eradicate disseminated prostate cancer in preclinical models

artículo científico publicado en 2014

Paclitaxel-hyaluronic acid for intravesical therapy of bacillus Calmette-Guérin refractory carcinoma in situ of the bladder: results of a phase I study

artículo científico publicado en 2010

Peritoneal tumor carcinomatosis: pharmacological targeting with hyaluronan-based bioconjugates overcomes therapeutic indications of current drugs

artículo científico publicado en 2014

Predicting tumor outcome following cancer vaccination by monitoring quantitative and qualitative CD8+ T cell parameters.

artículo científico publicado en 2006

Preliminary study of metabolic radiotherapy with 188Re via small animal imaging

Prolyl-isomerase Pin1 controls normal and cancer stem cells of the breast.

artículo científico publicado en 2013

Proteasome machinery is instrumental in a common gain-of-function program of the p53 missense mutants in cancer.

artículo científico publicado en 2016

Protein tyrosine kinases and phosphatases control apoptosis induced by extracellular adenosine 5'-triphosphate

artículo científico publicado en 1996

Quantitative imaging of the T cell antitumor response by positron-emission tomography.

artículo científico publicado en 2003

Radioisotopic purity and imaging properties of cyclotron-produced 99mTc using direct 100Mo(p,2n) reaction

scientific article published on 19 September 2018

Re-programming pullulan for targeting and controlled release of doxorubicin to the hepatocellular carcinoma cells.

artículo científico publicado en 2017

Real-Time Label-Free Targeting Assessment and in Vitro Characterization of Curcumin-Loaded Poly-lactic-co-glycolic Acid Nanoparticles for Oral Colon Targeting

scientific article published on 01 October 2019

Reprogramming T lymphocytes for melanoma adoptive immunotherapy by T-cell receptor gene transfer with lentiviral vectors.

artículo científico publicado en 2009

Retargeting cytokine-induced killer cell activity by CD16 engagement with clinical-grade antibodies

scientific article published on 30 June 2016

Retinoids as critical modulators of immune functions: new therapeutic perspectives for old compounds.

artículo científico publicado en 2009

Reverse immunoediting: When immunity is edited by antigen

artículo científico publicado en 2016

SHARP1 suppresses breast cancer metastasis by promoting degradation of hypoxia-inducible factors.

artículo científico publicado en 2012

Simulations and tests for metabolic radiotherapy with 188Re

Single-cell analyses reveal YAP/TAZ as regulators of stemness and cell plasticity in Glioblastoma

scientific article published on 07 December 2020

Site-Specific Transglutaminase-Mediated Conjugation of Interferon α-2b at Glutamine or Lysine Residues.

artículo científico publicado en 2016

Suppression of tumor growth and cell proliferation by p13II, a mitochondrial protein of human T cell leukemia virus type 1

artículo científico publicado en 2004

Survivin expression and prognostic significance in pediatric malignant peripheral nerve sheath tumors (MPNST).

artículo científico publicado en 2013

Survivin expression impacts prognostically on NSCLC but not SCLC

artículo científico publicado en 2013

Survivin in esophageal cancer: An accurate prognostic marker for squamous cell carcinoma but not adenocarcinoma

artículo científico publicado en 2006

Synergistic effect of extracellular adenosine 5'-triphosphate and tumor necrosis factor on DNA degradation

scientific article published on 01 November 1993

Synthesis and characterisation of a new benzamide-containing nitrobenzoxadiazole as a GSTP1-1 inhibitor endowed with high stability to metabolic hydrolysis

scientific article published on 01 December 2019

Synthesis and preliminary in vitro biological evaluation of 4-[(4-hydroxyphenyl)sulfanyl]but-3-en-2-one, a 4-mercaptophenol derivative designed as a novel bifunctional antimelanoma agent.

artículo científico publicado en 2009

The Hippo transducer TAZ confers cancer stem cell-related traits on breast cancer cells

artículo científico publicado en 2011

The interplay between Epstein-Barr virus and the immune system: a rationale for adoptive cell therapy of EBV-related disorders

artículo científico publicado en 2010

The mitochondrial calcium uniporter regulates breast cancer progression via HIF-1α.

artículo científico publicado en 2016

The nitrobenzoxadiazole derivative MC3181 blocks melanoma invasion and metastasis

artículo científico publicado en 2017

The prolyl-isomerase Pin1 is a Notch1 target that enhances Notch1 activation in cancer

artículo científico publicado en 2009

Therapeutical effect of 4'-deoxy-4'-iododoxorubicin-loaded LAK cells in mice bearing lung metastases

artículo científico publicado en 1992

Undifferentiated nasopharyngeal carcinoma from a nonendemic area: Protective role of HLA allele products presenting conserved EBV epitopes

artículo científico publicado en 2009

Wet sol-gel derived silica for controlled release of proteins

scientific article published on 26 September 2006

[99mTc][Tc(N)PNP43]-labeled RGD peptides as new probes for a selective detection of αvβ3 Integrin: synthesis, structure-activity and pharmacokinetic studies

scientific article published on 17 October 2018

[Anti-beta2 glycoprotein I-beta2 glycoprotein I] immune complexes in patients with antiphospholipid syndrome and other autoimmune diseases

artículo científico publicado en 1999

Lista de obras de Antonio Rosato

A BARF1-specific mAb as a new immunotherapeutic tool for the management of EBV-related tumors

A MicroRNA targeting dicer for metastasis control

A Mutant-p53/Smad complex opposes p63 to empower TGFbeta-induced metastasis

A Pin1/mutant p53 axis promotes aggressiveness in breast cancer

A YAP camera for the biodistribution of 188Re conjugated with Hyaluronic-Acid in “in vivo” systems

A covalent PIN1 inhibitor selectively targets cancer cells by a dual mechanism of action.

A human promyelocytic-like population is responsible for the immune suppression mediated by myeloid-derived suppressor cells.

A large number of T lymphocytes recognize Moloney-murine leukemia virus-induced antigens, but a few mediate long-lasting tumor immunosurveillance.

A non-covalent antibody complex for the delivery of anti-cancer drugs

A novel orally active water-soluble inhibitor of human glutathione transferase exerts a potent and selective antitumor activity against human melanoma xenografts

A paclitaxel-hyaluronan bioconjugate targeting ovarian cancer affords a potent in vivo therapeutic activity

A single-chain fragment against prostate specific membrane antigen as a tool to build theranostic reagents for prostate cancer.

A site-selective hyaluronan-interferonα2a conjugate for the treatment of ovarian cancer

Adoptive cell therapy against EBV-related malignancies: a survey of clinical results

Adoptive cell therapy of triple negative breast cancer with redirected cytokine-induced killer cells

Amniotic Fluid Stem Cells Restore the Muscle Cell Niche in a HSA-Cre, SmnF7/F7 Mouse Model

Anti-L-selectin monoclonal antibody treatment in mice enhances tumor growth by preventing CTL sensitization in peripheral lymph nodes draining the tumor area

Antitumour efficacy of lymphokine-activated killer cells loaded with ricin against experimentally induced lung metastases

Autologous cellular vaccine overcomes cancer immunoediting in a mouse model of myeloma.

Biodistribution imaging of a paclitaxel-hyaluronan bioconjugate.

Biokinetic and dosimetric studies of 188Re-hyaluronic acid: a new radiopharmaceutical for treatment of hepatocellular carcinoma

Broadening Specificity and Enhancing Cytotoxicity of Adoptive T Cells for Nasopharyngeal Carcinoma Immunotherapy.

CD45 regulates apoptosis induced by extracellular adenosine triphosphate and cytotoxic T lymphocytes.

CTL Response and Protection Against P815 Tumor Challenge in Mice Immunized with DNA Expressing the Tumor-Specific Antigen P815A

Cell-autonomous and cell non-autonomous downregulation of tumor suppressor DAB2IP by microRNA-149-3p promotes aggressiveness of cancer cells.

Combination of sorafenib and everolimus impacts therapeutically on adrenocortical tumor models.

Cytokines for the induction of antitumor effectors: The paradigm of Cytokine-Induced Killer (CIK) cells

DNA immunization of mice against SIVmac239 Gag and Env using Rev-independent expression plasmids

DNA-based vaccination against tumors expressing the P1A antigen

Delivery of methoxymorpholinyl doxorubicin by interleukin 2-activated NK cells: effect in mice bearing hepatic metastases

Design, synthesis and evaluation of biotin decorated inulin-based polymeric micelles as long-circulating nanocarriers for targeted drug delivery.

Diabetes-Associated Myelopoiesis Drives Stem Cell Mobilopathy Through an OSM-p66Shc Signaling Pathway

Differential down-modulation of HLA class I and II molecule expression on human tumor cell lines upon in vivo transfer.

Differential effect on TCR:CD3 stimulation of a 90-kD glycoprotein (gp90/Mac-2BP), a member of the scavenger receptor cysteine-rich domain protein family

Differential effects of angiostatin, endostatin and interferon-alpha(1) gene transfer on in vivo growth of human breast cancer cells.

Drug and protein delivery by polymer conjugation

Drug conjugation to hyaluronan widens therapeutic indications for ovarian cancer

Effect of antiadhesive agents on peritoneal carcinomatosis in an experimental model.

Enhanced EGFR Targeting Activity of Plasmonic Nanostructures with Engineered GE11 Peptide.

Exploiting the interplay between innate and adaptive immunity to improve immunotherapeutic strategies for Epstein-Barr-virus-driven disorders

Expression of survivin, p53, and caspase 3 in Barrett's esophagus carcinogenesis

Fast method for skeletal tissue gene expression analysis

Fighting Viral Infections and Virus-Driven Tumors with Cytotoxic CD4+ T Cells

Folic acid-conjugated europium complexes as luminescent probes for selective targeting of cancer cells

Functional avidity-driven activation-induced cell death shapes CTL immunodominance

Genome-wide association between YAP/TAZ/TEAD and AP-1 at enhancers drives oncogenic growth

Glucocorticoid receptor signalling activates YAP in breast cancer

Glutathione transferases as targets for cancer therapy.

HMGA1 promotes metastatic processes in basal-like breast cancer regulating EMT and stemness.

HYTAD1-p20: a new paclitaxel-hyaluronic acid hydrosoluble bioconjugate for treatment of superficial bladder cancer

Human IgGs induce synthesis and secretion of IgGs and neonatal Fc receptor in human umbilical vein endothelial cells.

Hyaluronic Acid as a Protein Polymeric Carrier: An Overview and a Report on Human Growth Hormone.

IGKV3 proteins as candidate "off-the-shelf" vaccines for kappa-light chain-restricted B-cell non-Hodgkin lymphomas.

Identification of a HLA-A*0201-restricted immunogenic epitope from the universal tumor antigen DEPDC1.

Identifying type Vicenza von Willebrand disease

Immunotherapeutic Strategies for Gastric Carcinoma: A Review of Preclinical and Clinical Recent Development.

Immunotherapy for EBV-associated malignancies.

Impact of γ-chain cytokines on EBV-specific T cell cultures.

Improvement of diaphragmatic performance through orthotopic application of decellularized extracellular matrix patch

In situ analysis of human menin in normal and neoplastic pancreatic tissues: evidence for differential expression in exocrine and endocrine cells

In vitro hepatic conversion of the anticancer agent nemorubicin to its active metabolite PNU-159682 in mice, rats and dogs: a comparison with human liver microsomes

In vivo fate of avidin-nucleic acid nanoassemblies as multifunctional diagnostic tools.

Individual analysis of mice vaccinated against a weakly immunogenic self tumor-specific antigen reveals a correlation between CD8 T cell response and antitumor efficacy.

Induction of Expandable Tissue-Specific Stem/Progenitor Cells through Transient Expression of YAP/TAZ.

Inflammatory polyarthropathy and bone remodeling in HTLV-I Tax-transgenic mice.

Inhibition of CTL-line lysis after gangliosides treatment

Inhibition of protein tyrosine phosphorylation prevents T-cell-mediated cytotoxicity

Internal radiation dose assessment of radiopharmaceuticals prepared with cyclotron-produced 99m Tc

Low-Dose Paclitaxel Reduces S100A4 Nuclear Import to Inhibit Invasion and Hematogenous Metastasis of Cholangiocarcinoma.

Mechanical cues control mutant p53 stability through a mevalonate-RhoA axis.

Melanoma targeting with [99mTc(N)(PNP3)]-labeled α-melanocyte stimulating hormone peptide analogs: Effects of cyclization on the radiopharmaceutical properties.

Membrane form of TNF alpha induces both cell lysis and apoptosis in susceptible target cells

Metabolic control of YAP and TAZ by the mevalonate pathway.

Mutant p53 reprograms TNF signaling in cancer cells through interaction with the tumor suppressor DAB2IP.

Novel [99mTcIII(PS)2(Ln)] mixed-ligand compounds (PS = phosphino-thiolate; L = dithiocarbamate) useful in design and development of TcIII-based agents: synthesis, in vitro, and ex vivo biodistribution studies

Novel types of carborane-carrier hyaluronan derivatives via "click chemistry".

Optical and multimodal peptide-based probes for in vivo molecular imaging.

PSMA-specific CAR-engineered T cells eradicate disseminated prostate cancer in preclinical models

Paclitaxel-hyaluronic acid for intravesical therapy of bacillus Calmette-Guérin refractory carcinoma in situ of the bladder: results of a phase I study