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Lista de obras de J Javier Meana

5-HT2A receptor-mediated Gαq/11 activation in psychiatric disorders: A postmortem study

scientific article published on 21 October 2020

A combined analysis of microarray gene expression studies of the human prefrontal cortex identifies genes implicated in schizophrenia.

artículo científico

A follow-up investigation on the quality of medical documents from examinations of Basque incommunicado detainees: the role of the medical doctors and national and international authorities in the prevention of ill-treatment and torture.

artículo científico publicado en 2008

Acute and chronic effects of desipramine and clorgyline on alpha(2)-adrenoceptors regulating noradrenergic transmission in the rat brain: a dual-probe microdialysis study

artículo científico publicado en 2001

Acute ethanol intoxication may not alter alpha 2-adrenoceptors in the human brain

artículo científico publicado en 1992

Additive effect of rimonabant and citalopram on extracellular serotonin levels monitored with in vivo microdialysis in rat brain

artículo científico publicado en 2013

Adenosine A1( )receptors are selectively coupled to Gα(i-3) in postmortem human brain cortex: Guanosine-5'-O-(3-[(35)S]thio)triphosphate ([(35)S]GTPγS) binding/immunoprecipitation study.

artículo científico publicado en 2015

Allosteric signaling through an mGlu2 and 5-HT2A heteromeric receptor complex and its potential contribution to schizophrenia

artículo científico publicado en 2016

Alpha 2-adrenoceptors in human forebrain: autoradiographic visualization and biochemical parameters using the agonist [3H]UK-14304

artículo científico publicado en 1988

Alpha 2-adrenoceptors in the brain of depressed suicide victims

artículo científico publicado el 1 de enero de 1992

Alpha 2-adrenoceptors in the brain of suicide victims: increased receptor density associated with major depression

artículo científico publicado en 1992

Alpha2C-adrenoceptor Del322-325 polymorphism and risk of psychiatric disorders: significant association with opiate abuse and dependence

artículo científico publicado en 2016

Altered CB1 receptor coupling to G-proteins in the post-mortem caudate nucleus and cerebellum of alcoholic subjects.

artículo científico publicado en 2015

Altered CSNK1E, FABP4 and NEFH protein levels in the dorsolateral prefrontal cortex in schizophrenia

artículo científico publicado en 2016

Aminopeptidase activity in the postmortem brain of human heroin addicts.

artículo científico publicado en 2004

Analysis of Sp transcription factors in the postmortem brain of chronic schizophrenia: a pilot study of relationship to negative symptoms.

artículo científico publicado en 2013

Antidepressant-like properties of three new α2-adrenoceptor antagonists

artículo científico publicado en 2012

Autoradiography of receptor-activated G-proteins in post mortem human brain

artículo científico publicado en 2000

Behavioral, neurochemical and morphological changes induced by the overexpression of munc18-1a in brain of mice: relevance to schizophrenia.

artículo científico publicado en 2013

Biased Agonism of Three Different Cannabinoid Receptor Agonists in Mouse Brain Cortex.

artículo científico publicado en 2016

Brain RGS4 and RGS10 protein expression in schizophrenia and depression. Effect of drug treatment.

artículo científico publicado en 2012

CCK in cerebral cortex and at the spinal level

artículo científico publicado en 1994

Cartography of hevin-expressing cells in the adult brain reveals prominent expression in astrocytes and parvalbumin neurons

scientific article published on 17 January 2019

Characterization and regional distribution of alpha 2-adrenoceptors in postmortem human brain using the full agonist [3H]UK 14304

scientific article published on 01 April 1989

Characterization of CB1 cannabinoid receptor immunoreactivity in postmortem human brain homogenates.

artículo científico publicado en 2006

Characterization of receptor-mediated [35S]GTPgammaS binding to cortical membranes from postmortem human brain

scientific article published on 01 February 2000

Chronic cannabis promotes pro-hallucinogenic signaling of 5-HT2A receptors through Akt/mTOR pathway

artículo científico publicado en 2018

Chronic nicotine treatment counteracts the decrease in extracellular neostriatal dopamine induced by a unilateral transection at the mesodiencephalic junction in rats: a microdialysis study

artículo científico publicado en 1991

Chronic pain leads to concomitant noradrenergic impairment and mood disorders.

artículo científico publicado en 2012

Correction to α2-Adrenoceptor Antagonists: Synthesis, Pharmacological Evaluation, and Molecular Modeling Investigation of Pyridinoguanidine, Pyridino-2-aminoimidazoline and Their Derivatives

artículo científico publicado en 2015

Cyclin-dependent kinase-5 and p35/p25 activators in schizophrenia and major depression prefrontal cortex: basal contents and effects of psychotropic medications

artículo científico publicado en 2012

Decreased density of presynaptic alpha 2-adrenoceptors in postmortem brains of patients with Alzheimer's disease

artículo científico publicado el 1 de mayo de 1992

Densities of I2-imidazoline receptors, imidazoline receptor proteins, and MAO-B sites in human gliomas and pituitary adenomas

artículo científico publicado en 1999

Description of a bivalent cannabinoid ligand with hypophagic properties

artículo científico publicado en 2013

Determination of the somatodendritic alpha2-adrenoceptor subtype located in rat locus coeruleus that modulates cortical noradrenaline release in vivo

artículo científico publicado en 1999

Differences in criminal activity between heroin abusers and subjects without psychiatric disorders--analysis of 578 detainees in Bilbao, Spain

artículo científico publicado el 1 de septiembre de 1998

Differential [(3)H]idazoxan and [(3)H]2-(2-benzofuranyl)-2-imidazoline (2-BFI) binding to imidazoline I(2) receptors in human postmortem frontal cortex.

artículo científico publicado en 2001

Differential modulation of alpha2-adrenoceptor subtypes in rat kidney by chronic desipramine treatment

artículo científico publicado en 1999

Differential postmortem delay effect on agonist-mediated phospholipase Cbeta activity in human cortical crude and synaptosomal brain membranes.

artículo científico publicado en 2004

Differential regulation of RGS proteins in the prefrontal cortex of short- and long-term human opiate abusers.

artículo científico publicado en 2011

Dissociation between I2-imidazoline receptors and MAO-B activity in platelets of patients with Alzheimer's type dementia.

artículo científico publicado en 1999

Distribution of prolyl endopeptidase activities in rat and human brain

scientific journal article

Dopaminergic control of ADAMTS2 expression through cAMP/CREB and ERK: molecular effects of antipsychotics

artículo científico publicado en 2019

Dysregulated 5-HT(2A) receptor binding in postmortem frontal cortex of schizophrenic subjects

artículo científico publicado en 2012

Effect of subchronic corticosterone administration on α2-adrenoceptor functionality in rat brain: an in vivo and in vitro study.

artículo científico publicado en 2016

Effect of the neurotoxin AF64A on intrinsic and extrinsic neuronal systems of rat neostriatum measured by in vivo microdialysis

artículo científico publicado en 1992

Effects of age, postmortem delay and storage time on receptor-mediated activation of G-proteins in human brain.

artículo científico publicado en 2002

Endocannabinoid system imbalance in the postmortem prefrontal cortex of subjects with schizophrenia

scientific article published on 25 June 2019

Evaluation of 5-HT2A and mGlu2/3 receptors in postmortem prefrontal cortex of subjects with major depressive disorder: effect of antidepressant treatment.

artículo científico publicado en 2014

FADD adaptor and PEA-15/ERK1/2 partners in major depression and schizophrenia postmortem brains: basal contents and effects of psychotropic treatments

artículo científico publicado en 2014

Fentanyl derivatives bearing aliphatic alkaneguanidinium moieties: a new series of hybrid molecules with significant binding affinity for mu-opioid receptors and I2-imidazoline binding sites.

artículo científico publicado en 2004

Gi protein coupling to adenosine A1-A2A receptor heteromers in human brain caudate nucleus.

artículo científico publicado en 2010

Group II Metabotropic Glutamate Receptors as Targets for Novel Antipsychotic Drugs

artículo científico publicado en 2016

Guanidine and 2-Aminoimidazoline Aromatic Derivatives as α2-Adrenoceptor Antagonists, 1: Toward New Antidepressants with Heteroatomic Linkers

artículo científico publicado en 2007

Guanidine and 2-aminoimidazoline aromatic derivatives as alpha2-adrenoceptor antagonists. 2. Exploring alkyl linkers for new antidepressants.

artículo científico publicado en 2008

Guanidine and 2-aminoimidazoline aromatic derivatives as alpha2-adrenoceptor ligands: searching for structure-activity relationships

artículo científico publicado en 2009

Guanidinium and aminoimidazolinium derivatives of N-(4-piperidyl)propanamides as potential ligands for mu opioid and I2-imidazoline receptors: synthesis and pharmacological screening.

artículo científico publicado en 2002

HDAC2 regulates atypical antipsychotic responses through the modulation of mGlu2 promoter activity.

artículo científico publicado en 2012

Heterotrimeric g proteins: insights into the neurobiology of mood disorders.

artículo científico publicado en 2006

Human adenosine deaminase as an allosteric modulator of human A(1) adenosine receptor: abolishment of negative cooperativity for [H](R)-pia binding to the caudate nucleus

artículo científico publicado en 2008

I(2)-imidazoline binding site affinity of a structurally different type of ligands.

artículo científico publicado en 2002

I2-Imidazoline receptors and monoamine oxidase B enzyme sites in human brain: covariation with age

artículo científico publicado en 2000

I2-imidazoline receptors in the healthy and pathologic human brain.

artículo científico publicado en 1995

Identification of a serotonin/glutamate receptor complex implicated in psychosis

artículo científico publicado en 2008

Identification of three residues essential for 5-hydroxytryptamine 2A-metabotropic glutamate 2 (5-HT2A·mGlu2) receptor heteromerization and its psychoactive behavioral function

artículo científico publicado en 2012

Imidazoline I(2) receptor density increases with the malignancy of human gliomas

artículo científico publicado en 2004

Immunodensity and mRNA expression of A2A adenosine, D2 dopamine, and CB1 cannabinoid receptors in postmortem frontal cortex of subjects with schizophrenia: effect of antipsychotic treatment

artículo científico publicado en 2009

Immunohistochemical evidence for a crossed cholecystokinin corticostriatal pathway in the rat.

artículo científico publicado en 1992

In vivo modulation of norepinephrine and glutamate release through imidazoline receptors in the rat central nervous system

artículo científico publicado en 1995

In vivo potentiation of reboxetine and citalopram effect on extracellular noradrenaline in rat brain by α2-adrenoceptor antagonism.

artículo científico publicado en 2010

In vivo tonic modulation of the noradrenaline release in the rat cortex by locus coeruleus somatodendritic alpha(2)-adrenoceptors.

artículo científico publicado en 2002

Increased [3H] raclopride binding sites in postmortem brains from schizophrenic violent suicide victims

artículo científico publicado en 1992

Increased alpha 2-adrenoceptor density in the frontal cortex of depressed suicide victims

artículo científico publicado en 1987

Increased density of mu-opioid receptors in the postmortem brain of suicide victims

artículo científico publicado en 1995

Increased α2- and β1-adrenoceptor densities in postmortem brain of subjects with depression: differential effect of antidepressant treatment

artículo científico publicado en 2014

Inhibition of 5-hydroxytryptamine reuptake by the antidepressant citalopram in the locus coeruleus modulates the rat brain noradrenergic transmission in vivo

artículo científico publicado en 2000

Involvement of serotonin 5-HT3 receptors in the modulation of noradrenergic transmission by serotonin reuptake inhibitors: a microdialysis study in rat brain

artículo científico publicado en 2013

Levels of G-protein alpha q/11 subunits and of phospholipase C-beta(1-4), -gamma, and -delta1 isoforms in postmortem human brain caudate and cortical membranes: potential functional implications.

artículo científico publicado en 2006

Levels of Gsα(short and long), Gα(olf) and Gβ(common) subunits, and calcium-sensitive adenylyl cyclase isoforms (1, 5/6, 8) in post-mortem human brain caudate and cortical membranes: comparison with rat brain membranes and potential stoichiometric r

artículo científico publicado en 2010

Long lasting effects of early-life stress on glutamatergic/GABAergic circuitry in the rat hippocampus

artículo científico publicado en 2012

Long-acting fentanyl analogues: synthesis and pharmacology of N-(1-phenylpyrazolyl)-N-(1-phenylalkyl-4-piperidyl)propanamides.

artículo científico publicado en 2002

Low-affinity conditions for agonists increase the binding of the antagonist [3H]RX821002 to the alpha(2B/C)-adrenoceptor subtypes in human brain and rat kidney

artículo científico publicado en 1997

Modulation of catecholamine release by alpha 2-adrenoceptors and I1-imidazoline receptors in rat brain

scientific article published on 01 January 1997

Molecular adaptations of apoptotic pathways and signaling partners in the cerebral cortex of human cocaine addicts and cocaine-treated rats

scientific journal article

Monoamine oxidase B activity is increased in human gliomas.

artículo científico publicado en 2007

Neuronal dependence of extracellular dopamine, acetylcholine, glutamate, aspartate and gamma-aminobutyric acid (GABA) measured simultaneously from rat neostriatum using in vivo microdialysis: reciprocal interactions

artículo científico publicado en 1992

Neurotransmitter receptor-mediated activation of G-proteins in brains of suicide victims with mood disorders: selective supersensitivity of alpha(2A)-adrenoceptors.

artículo científico publicado en 2002

Next-Generation Proteomics of Brain Extracellular Vesicles in Schizophrenia Provide New Clues on the Altered Molecular Connectome

artículo científico publicado en 2024

Non-adrenoceptor [3H]idazoxan binding sites (I2-imidazoline sites) are increased in postmortem brain from patients with Alzheimer's disease.

artículo científico publicado en 1993

Novel synthesis and pharmacological evaluation as alpha2-adrenoceptor ligands of O-phenylisouronium salts

artículo científico publicado en 2008

On the release of glutamate and aspartate in the basal ganglia of the rat: interactions with monoamines and neuropeptides.

artículo científico publicado en 1997

On the search of new I2-IBS aliphatic ligands: Bis-guanidino carbonyl derivatives

artículo científico publicado en 2007

Opposite changes in cannabinoid CB1 and CB2 receptor expression in human gliomas.

artículo científico publicado en 2010

Opposite changes in imidazoline I2 receptors and alpha2-adrenoceptors density in rat frontal cortex after induced gliosis

artículo científico publicado en 2005

Pharmacological characterization and autoradiographic distribution of alpha2-adrenoceptor antagonist [3H]RX 821002 binding sites in the chicken brain

artículo científico publicado en 2006

Phosphorylation of FADD (Fas-associated death domain protein) at serine 194 is increased in the prefrontal cortex of opiate abusers: relation to mitogen activated protein kinase, phosphoprotein enriched in astrocytes of 15 kDa, and Akt signaling pat

artículo científico publicado en 2009

Quantification of endocannabinoids in postmortem brain of schizophrenic subjects

artículo científico publicado en 2013

Quantitative stoichiometry of G-proteins activated by mu-opioid receptors in postmortem human brain

artículo científico publicado en 2002

Recent cocaine use is a significant risk factor for sudden cardiovascular death in 15-49-year-old subjects: a forensic case-control study

artículo científico publicado en 2014

Reduced platelet G protein-coupled receptor kinase 2 in major depressive disorder: antidepressant treatment-induced upregulation of GRK2 protein discriminates between responder and non-responder patients

artículo científico publicado en 2010

Regulation of central noradrenergic activity by 5-HT(3) receptors located in the locus coeruleus of the rat.

artículo científico publicado en 2012

Regulation of munc18-1 and syntaxin-1A interactive partners in schizophrenia prefrontal cortex: down-regulation of munc18-1a isoform and 75 kDa SNARE complex after antipsychotic treatment

artículo científico publicado en 2011

Regulation of phospholipase Cbeta activity by muscarinic acetylcholine and 5-HT(2) receptors in crude and synaptosomal membranes from human cerebral cortex.

artículo científico publicado en 2001

Relationship between non-functional masticatory activity and central dopamine in stressed rats.

artículo científico publicado en 2010

Release of endogenous excitatory amino acids in the neostriatum of the rat under physiological and pharmacologically-induced conditions.

artículo científico publicado en 1998

Screening and quantification of antipsychotic drugs in human brain tissue by liquid chromatography-tandem mass spectrometry: application to postmortem diagnostics of forensic interest

artículo científico publicado en 2012

Selective Increase of α2A‐Adrenoceptor Agonist Binding Sites in Brains of Depressed Suicide Victims

artículo científico publicado el 1 de marzo de 1998

Semaphorin and plexin gene expression is altered in the prefrontal cortex of schizophrenia patients with and without auditory hallucinations

article

Serotonin 5-HT2A receptors in schizophrenia: Reflexions on an unfinished story

artículo científico publicado en 2023

Simultaneous determination of cholecystokinin, dopamine, glutamate and aspartate in cortex and striatum of the rat using in vivo microdialysis

artículo científico publicado en 1991

Somatodendritic α2‐Adrenoceptors in the Locus Coeruleus Are Involved in the In Vivo Modulation of Cortical Noradrenaline Release by the Antidepressant Desipramine

artículo científico publicado el 1 de agosto de 1998

Specific binding of [3H]Ro 19-6327 (lazabemide) to monoamine oxidase B is increased in frontal cortex of suicide victims after controlling for age at death.

artículo científico publicado en 2007

Structural and Functional Characterization of the Interaction of Snapin with the Dopamine Transporter: Differential Modulation of Psychostimulant Actions.

artículo científico publicado en 2017

Synthesis and pharmacological studies of new hybrid derivatives of fentanyl active at the mu-opioid receptor and I2-imidazoline binding sites

artículo científico publicado en 2006

The N251K functional polymorphism in the alpha(2A)-adrenoceptor gene is not associated with depression: a study in suicide completers

artículo científico publicado en 2005

The endocannabinoid system is altered in the post-mortem prefrontal cortex of alcoholic subjects

artículo científico publicado en 2014

The function of alpha-2-adrenoceptors in the rat locus coeruleus is preserved in the chronic constriction injury model of neuropathic pain

artículo científico publicado en 2011

The inverse agonist effect of rimonabant on G protein activation is not mediated by the cannabinoid CB1 receptor: Evidence from postmortem human brain

artículo científico publicado en 2011

The subtype-selective alpha 2-adrenoceptor antagonists BRL 44408 and ARC 239 also recognize 5-HT1A receptors in the rat brain

artículo científico publicado en 1996

The transcription factor SP4 is reduced in postmortem cerebellum of bipolar disorder subjects: control by depolarization and lithium

artículo científico publicado el 1 de agosto de 2011

Transcription factor SP4 phosphorylation is altered in the postmortem cerebellum of bipolar disorder and schizophrenia subjects

artículo científico publicado en 2015

Transcription factor Sp4 regulates expression of nervous wreck 2 to control NMDAR1 levels and dendrite patterning.

artículo científico publicado en 2014

Up-regulated 14-3-3β and 14-3-3ζ proteins in prefrontal cortex of subjects with schizophrenia: effect of psychotropic treatment

artículo científico publicado en 2014

[3H]RX821002 (2-methoxyidazoxan) binds to alpha 2-adrenoceptor subtypes and a non-adrenoceptor imidazoline binding site in rat kidney

artículo científico publicado en 1996

mu-Opioid receptor and alpha 2-adrenoceptor agonist binding sites in the postmortem brain of heroin addicts

artículo científico publicado en 1994

mu-opioid receptor and alpha2-adrenoceptor agonist stimulation of [35S]GTPgammaS binding to G-proteins in postmortem brains of opioid addicts

artículo científico publicado en 2000

α2-Adrenoceptor Functionality in Postmortem Frontal Cortex of Depressed Suicide Victims

artículo científico publicado el 22 de septiembre de 2010

α2-adrenoceptor antagonists: synthesis, pharmacological evaluation, and molecular modeling investigation of pyridinoguanidine, pyridino-2-aminoimidazoline and their derivatives

artículo científico publicado en 2015