Lista de obras - Michele Galluccio - Dominio Público Uruguay

Bacterial Production, Characterization and Protein Modeling of a Novel Monofuctional Isoform of FAD Synthase in Humans: An Emergency Protein?

artículo científico publicado en 2018

Bacterial over-expression and purification of the 3'phosphoadenosine 5'phosphosulfate (PAPS) reductase domain of human FAD synthase: functional characterization and homology modeling

artículo científico publicado en 2012

Bacterial production and reconstitution in proteoliposomes of Solanum lycopersicum CAT2: a transporter of basic amino acids and organic cations.

artículo científico publicado en 2017

Biosynthesis of flavin cofactors in man: implications in health and disease.

artículo científico publicado en 2013

Chemical Approaches for Studying the Biology and Pharmacology of Membrane Transporters: The Histidine/Large Amino Acid Transporter SLC7A5 as a Benchmark

artículo científico publicado en 2021

Cloning, large scale over-expression in E. coli and purification of the components of the human LAT 1 (SLC7A5) amino acid transporter

artículo científico publicado en 2013

Discovery of Potent Inhibitors for the Large Neutral Amino Acid Transporter 1 (LAT1) by Structure-Based Methods ⬇️

journal article from 'International Journal of Molecular Sciences' published in 2019

Effect of Cholesterol on the Organic Cation Transporter OCTN1 (SLC22A4)

artículo científico publicado en 2020

Exploiting Cysteine Residues of SLC Membrane Transporters as Targets for Drugs

scientific article published on 28 June 2019

Functional and molecular effects of mercury compounds on the human OCTN1 cation transporter: C50 and C136 are the targets for potent inhibition

artículo científico publicado en 2014

Functional reconstitution into liposomes and characterization of the carnitine transporter from rat liver microsomes

artículo científico publicado en 2006

Glutamine Transport and Mitochondrial Metabolism in Cancer Cell Growth.

artículo científico publicado en 2017

Glutamine transport. From energy supply to sensing and beyond

artículo científico publicado en 2016

Human FAD synthase (isoform 2): a component of the machinery that delivers FAD to apo-flavoproteins

scientific article published on 20 October 2011

Human FAD synthase is a bi-functional enzyme with a FAD hydrolase activity in the molybdopterin binding domain

artículo científico publicado en 2015

Human OCTN2 (SLC22A5) is down-regulated in virus- and nonvirus-mediated cancer.

artículo científico publicado en 2012

Inactivation by Hg2+ and methylmercury of the glutamine/amino acid transporter (ASCT2) reconstituted in liposomes: Prediction of the involvement of a CXXC motif by homology modelling

artículo científico publicado en 2010

Inflammation and Organic Cation Transporters Novel (OCTNs)

artículo científico publicado en 2024

Insights into the transport side of the human SLC38A9 transceptor

scientific article published on 08 July 2019

Interaction of beta-lactam antibiotics with the mitochondrial carnitine/acylcarnitine transporter

artículo científico publicado en 2008

LAT1 is the transport competent unit of the LAT1/CD98 heterodimeric amino acid transporter.

artículo científico publicado en 2015

Large scale production of the active human ASCT2 (SLC1A5) transporter in Pichia pastoris--functional and kinetic asymmetry revealed in proteoliposomes

artículo científico publicado en 2013

Membrane Transporters for Amino Acids as Players of Cancer Metabolic Rewiring

artículo científico publicado en 2020

Membrane transporters for the special amino acid glutamine: structure/function relationships and relevance to human health.

artículo científico publicado en 2014

Mitochondrial localization of human FAD synthetase isoform 1.

artículo científico publicado en 2010

Mutation of Aspartate 238 in FAD Synthase Isoform 6 Increases the Specific Activity by Weakening the FAD Binding ⬇️

artículo científico

Nesfatin-1 as a novel cardiac peptide: identification, functional characterization, and protection against ischemia/reperfusion injury.

artículo científico publicado en 2012

Novel insights into the transport mechanism of the human amino acid transporter LAT1 (SLC7A5). Probing critical residues for substrate translocation

artículo científico publicado en 2017

OCTN Cation Transporters in Health and Disease: Role as Drug Targets and Assay Development ⬇️

artículo científico publicado el 14 de junio de 2013

OCTN: A Small Transporter Subfamily with Great Relevance to Human Pathophysiology, Drug Discovery, and Diagnostics

scientific article published on 07 December 2018

Over-expression in E. coli and purification of the human OCTN1 transport protein.

artículo científico publicado en 2009

Over-expression in E. coli and purification of the human OCTN2 transport protein

artículo científico publicado en 2012

Over-expression in Escherichia coli and characterization of two recombinant isoforms of human FAD synthetase.

artículo científico publicado en 2006

Over-expression in Escherichia coli, purification and characterization of isoform 2 of human FAD synthetase

artículo científico publicado en 2007

Over-expression in Escherichia coli, purification and reconstitution in liposomes of the third member of the OCTN sub-family: the mouse carnitine transporter OCTN3.

artículo científico publicado en 2012

Potent inhibitors of human LAT1 (SLC7A5) transporter based on dithiazole and dithiazine compounds for development of anticancer drugs.

artículo científico publicado en 2017

Reconstitution in liposomes of the functionally active human OCTN1 (SLC22A4) transporter overexpressed in Escherichia coli

artículo científico publicado en 2011

Reconstitution into liposomes of the glutamine/amino acid transporter from renal cell plasma membrane: functional characterization, kinetics and activation by nucleotides.

artículo científico publicado en 2004

Regulation by physiological cations of acetylcholine transport mediated by human OCTN1 (SLC22A4). Implications in the non-neuronal cholinergic system

artículo científico publicado en 2012

Regulatory Aspects of the Vacuolar CAT2 Arginine Transporter of : Role of Osmotic Pressure and Cations

scientific article published on 19 February 2019

Riboflavin transport and metabolism in humans

artículo científico publicado en 2016

Riboflavin-Responsive and -Non-responsive Mutations in FAD Synthase Cause Multiple Acyl-CoA Dehydrogenase and Combined Respiratory-Chain Deficiency

artículo científico publicado en 2016

SLC38A9 is a component of the lysosomal amino acid sensing machinery that controls mTORC1

artículo científico publicado en 2015

Significance of redox-active cysteines in human FAD synthase isoform 2

scholarly article by Angelica Miccolis published in December 2014

Strategies of bacterial over expression of membrane transporters relevant in human health: the successful case of the three members of OCTN subfamily ⬇️

artículo científico publicado el 1 de junio de 2013

Structure/function relationships of the human mitochondrial ornithine/citrulline carrier by Cys site-directed mutagenesis. Relevance to mercury toxicity

scientific article published on 16 August 2018

Studying interactions of drugs with cell membrane nutrient transporters: new frontiers of proteoliposome nanotechnology.

artículo científico publicado en 2017

The Human SLC7A5 (LAT1): The Intriguing Histidine/Large Neutral Amino Acid Transporter and Its Relevance to Human Health.

artículo científico publicado en 2018

The glutamine/amino acid transporter (ASCT2) reconstituted in liposomes: transport mechanism, regulation by ATP and characterization of the glutamine/glutamate antiport

artículo científico publicado en 2006

The hidden side of the human FAD synthase 2

scientific article published on 24 July 2019

The human OCTN1 (SLC22A4) reconstituted in liposomes catalyzes acetylcholine transport which is defective in the mutant L503F associated to the Crohn's disease.

artículo científico publicado en 2011

Lista de obras de Michele Galluccio

Bacterial Production, Characterization and Protein Modeling of a Novel Monofuctional Isoform of FAD Synthase in Humans: An Emergency Protein?

Bacterial over-expression and purification of the 3'phosphoadenosine 5'phosphosulfate (PAPS) reductase domain of human FAD synthase: functional characterization and homology modeling

Bacterial production and reconstitution in proteoliposomes of Solanum lycopersicum CAT2: a transporter of basic amino acids and organic cations.

Biosynthesis of flavin cofactors in man: implications in health and disease.

Chemical Approaches for Studying the Biology and Pharmacology of Membrane Transporters: The Histidine/Large Amino Acid Transporter SLC7A5 as a Benchmark

Cloning, large scale over-expression in E. coli and purification of the components of the human LAT 1 (SLC7A5) amino acid transporter

Discovery of Potent Inhibitors for the Large Neutral Amino Acid Transporter 1 (LAT1) by Structure-Based Methods ⬇️

Effect of Cholesterol on the Organic Cation Transporter OCTN1 (SLC22A4)

Exploiting Cysteine Residues of SLC Membrane Transporters as Targets for Drugs

Functional and molecular effects of mercury compounds on the human OCTN1 cation transporter: C50 and C136 are the targets for potent inhibition

Functional reconstitution into liposomes and characterization of the carnitine transporter from rat liver microsomes

Glutamine Transport and Mitochondrial Metabolism in Cancer Cell Growth.

Glutamine transport. From energy supply to sensing and beyond

Human FAD synthase (isoform 2): a component of the machinery that delivers FAD to apo-flavoproteins

Human FAD synthase is a bi-functional enzyme with a FAD hydrolase activity in the molybdopterin binding domain

Human OCTN2 (SLC22A5) is down-regulated in virus- and nonvirus-mediated cancer.

Inactivation by Hg2+ and methylmercury of the glutamine/amino acid transporter (ASCT2) reconstituted in liposomes: Prediction of the involvement of a CXXC motif by homology modelling

Inflammation and Organic Cation Transporters Novel (OCTNs)

Insights into the transport side of the human SLC38A9 transceptor

Interaction of beta-lactam antibiotics with the mitochondrial carnitine/acylcarnitine transporter

LAT1 is the transport competent unit of the LAT1/CD98 heterodimeric amino acid transporter.

Large scale production of the active human ASCT2 (SLC1A5) transporter in Pichia pastoris--functional and kinetic asymmetry revealed in proteoliposomes

Membrane Transporters for Amino Acids as Players of Cancer Metabolic Rewiring

Membrane transporters for the special amino acid glutamine: structure/function relationships and relevance to human health.

Mitochondrial localization of human FAD synthetase isoform 1.

Mutation of Aspartate 238 in FAD Synthase Isoform 6 Increases the Specific Activity by Weakening the FAD Binding ⬇️

Nesfatin-1 as a novel cardiac peptide: identification, functional characterization, and protection against ischemia/reperfusion injury.

Novel insights into the transport mechanism of the human amino acid transporter LAT1 (SLC7A5). Probing critical residues for substrate translocation

OCTN Cation Transporters in Health and Disease: Role as Drug Targets and Assay Development ⬇️

OCTN: A Small Transporter Subfamily with Great Relevance to Human Pathophysiology, Drug Discovery, and Diagnostics

Over-expression in E. coli and purification of the human OCTN1 transport protein.

Over-expression in E. coli and purification of the human OCTN2 transport protein

Over-expression in Escherichia coli and characterization of two recombinant isoforms of human FAD synthetase.

Over-expression in Escherichia coli, purification and characterization of isoform 2 of human FAD synthetase

Over-expression in Escherichia coli, purification and reconstitution in liposomes of the third member of the OCTN sub-family: the mouse carnitine transporter OCTN3.

Potent inhibitors of human LAT1 (SLC7A5) transporter based on dithiazole and dithiazine compounds for development of anticancer drugs.

Reconstitution in liposomes of the functionally active human OCTN1 (SLC22A4) transporter overexpressed in Escherichia coli

Reconstitution into liposomes of the glutamine/amino acid transporter from renal cell plasma membrane: functional characterization, kinetics and activation by nucleotides.

Regulation by physiological cations of acetylcholine transport mediated by human OCTN1 (SLC22A4). Implications in the non-neuronal cholinergic system

Regulatory Aspects of the Vacuolar CAT2 Arginine Transporter of : Role of Osmotic Pressure and Cations

Riboflavin transport and metabolism in humans

Riboflavin-Responsive and -Non-responsive Mutations in FAD Synthase Cause Multiple Acyl-CoA Dehydrogenase and Combined Respiratory-Chain Deficiency

SLC38A9 is a component of the lysosomal amino acid sensing machinery that controls mTORC1

Significance of redox-active cysteines in human FAD synthase isoform 2

Strategies of bacterial over expression of membrane transporters relevant in human health: the successful case of the three members of OCTN subfamily ⬇️

Structure/function relationships of the human mitochondrial ornithine/citrulline carrier by Cys site-directed mutagenesis. Relevance to mercury toxicity

Studying interactions of drugs with cell membrane nutrient transporters: new frontiers of proteoliposome nanotechnology.

The Human SLC7A5 (LAT1): The Intriguing Histidine/Large Neutral Amino Acid Transporter and Its Relevance to Human Health.

The glutamine/amino acid transporter (ASCT2) reconstituted in liposomes: transport mechanism, regulation by ATP and characterization of the glutamine/glutamate antiport

The hidden side of the human FAD synthase 2

The human OCTN1 (SLC22A4) reconstituted in liposomes catalyzes acetylcholine transport which is defective in the mutant L503F associated to the Crohn's disease.