Lista de obras - Malcolm D Tingle - Dominio Público Uruguay

3'-azido-3'-deoxythymidine (AZT) induces apoptosis and alters metabolic enzyme activity in human placenta

artículo científico publicado en 2003

A difference between the rat and mouse in the pharmacokinetic interaction of 5,6-dimethylxanthenone-4-acetic acid with thalidomide

artículo científico publicado en 2001

A systematic review of clozapine-induced myocarditis.

artículo científico publicado en 2018

Abstract 2532: Triethylenetetramine metabolism and its implication in cancer chemotherapy

artículo científico publicado en 2011

Adenosine amine congener as a cochlear rescue agent

artículo científico publicado en 2014

Aerobic 2- and 4-nitroreduction of CB 1954 by human liver

artículo científico publicado en 2005

An Investigation into the Haematological Toxicity of Structural Analogues of Dapsone In-vivo and In-vitro

artículo científico publicado en 1991

An investigation of the formation of cytotoxic, genotoxic, protein-reactive and stable metabolites from naphthalene by human liver microsomes

scientific article published on 01 November 1993

Antimutagenic effects of wheat bran diet through modification of xenobiotic metabolising enzymes

artículo científico publicado en 2000

Ascending single dose pharmacokinetics of cytisine in healthy adult smokers

artículo científico publicado en 2018

Bioactivation and inactivation of aflatoxin B1 by human, mouse and rat liver preparations: effect on SCE in human mononuclear leucocytes.

artículo científico publicado en 1997

COMPARATIVE PROTEIN BINDING, STABILITY AND DEGRADATION OF SATRAPLATIN, JM118 AND CISPLATIN IN HUMAN PLASMAIN VITRO

artículo científico publicado en 2008

Circulating microRNA as biomarkers of clozapine-induced cardiotoxicity

artículo científico publicado en 2019

Determination of two major metabolites of the novel anti-tumour agent 5,6-dimethylxanthenone-4-acetic acid in hepatic microsomal incubations by high-performance liquid chromatography with fluorescence detection

artículo científico publicado en 1999

Drug-protein conjugates—XIV

artículo científico publicado en 1988

Effects of anticancer drugs on the metabolism of the anticancer drug 5,6-dimethylxanthenone-4-acetic (DMXAA) by human liver microsomes

artículo científico publicado en 2001

Evaluation of the generation of genotoxic and cytotoxic metabolites of benzo[a]pyrene, aflatoxin B1, naphthalene and tamoxifen using human liver microsomes and human lymphocytes

artículo científico publicado en 1995

Gender differences in the metabolism and pharmacokinetics of the experimental anticancer agent 5,6-dimethylxanthenone-4-acetic acid (DMXAA).

artículo científico publicado en 2001

Glucuronidation of anticancer prodrug PR-104A: species differences, identification of human UDP-glucuronosyltransferases, and implications for therapy

artículo científico publicado en 2011

Gonadal influence on the metabolism and haematological toxicity of dapsone in the rat.

artículo científico publicado en 1990

Hepatic nitroreduction, toxicity and toxicokinetics of the anti-tumour prodrug CB 1954 in mouse and rat

artículo científico publicado en 2007

Human placental glucuronidation and transport of 3'azido-3'-deoxythymidine and uridine diphosphate glucuronic acid

artículo científico publicado en 2004

Identification and reactivity of the major metabolite (beta-1-glucuronide) of the anti-tumour agent 5,6-dimethylxanthenone-4-acetic acid (DMXAA) in humans

artículo científico publicado en 2001

In vitro and in vivo kinetic interactions of the antitumour agent 5,6-dimethylxanthenone-4-acetic acid with thalidomide and diclofenac

artículo científico publicado en 2001

In vitro metabolism of norbormide in rat, mouse and guinea pig liver preparations

artículo científico publicado en 2008

In vivo metabolism of norbormide in rats and mice

artículo científico publicado en 2009

Indirect regulation of CYP2C19 gene expression via DNA methylation.

artículo científico publicado en 2017

Influence of mustard group structure on pathways of in vitro metabolism of anticancer N-(2-hydroxyethyl)-3,5-dinitrobenzamide 2-mustard prodrugs

artículo científico publicado en 2007

Inhibition of Dapsone-Induced Methaemoglobinaemia by Cimetidine in the Rat During Chronic Dapsone Administration

artículo científico publicado en 1991

Inhibition of Dapsone-induced Methaemoglobinaemia by Cimetidine in the Presence of Trimethoprim in the Rat

artículo científico publicado en 1992

Measuring antibiotic levels and their relationship with the microbiome in chronic rhinosinusitis

scientific article published on 07 October 2019

Metabolic interactions with piperazine-based 'party pill' drugs

artículo científico publicado en 2009

Metabolism of praziquantel in kingfish Seriola lalandi

artículo científico publicado en 2008

Metabolism of thalidomide in liver microsomes of mice, rabbits, and humans

artículo científico publicado en 2004

Oral antibiotics used in the treatment of chronic rhinosinusitis have limited penetration into the sinonasal mucosa: a randomized trial

artículo científico publicado en 2020

Pharmacokinetic Properties of Adenosine Amine Congener in Cochlear Perilymph after Systemic Administration

artículo científico publicado en 2017

Pharmacokinetics and in vivo chemosuppressive activity studies on cryptolepine hydrochloride and cryptolepine hydrochloride-loaded gelatine nanoformulation designed for parenteral administration for the treatment of malaria

artículo científico publicado en 2013

Pharmacokinetics of cytisine, an α4β2nicotinic receptor partial agonist, in healthy smokers following a single dose

article

Rapid biotransformation of satraplatin by human red blood cells in vitro

artículo científico publicado en 2002

Regulating new psychoactive drugs: innovation leading to compromise.

artículo científico publicado en 2014

Reversible binding of the novel anti-tumour agent 5,6-dimethylxanthenone-4-acetic acid to plasma proteins and its distribution into blood cells in various species

artículo científico publicado en 2001

Satraplatin activation by haemoglobin, cytochrome C and liver microsomes in vitro

artículo científico publicado en 2005

Species differences in the metabolism of the antitumour agent 5,6-dimethylxanthenone-4-acetic acid in vitro: implications for prediction of metabolic interactions in vivo

artículo científico publicado en 2002

Specific determination of intact cisplatin and monohydrated cisplatin in human plasma and culture medium ultrafiltrates using HPLC on-line with inductively coupled plasma mass spectrometry

artículo científico publicado en 2006

Structural basis for the haemotoxicity of dapsone: the importance of the sulphonyl group

artículo científico publicado en 1997

Synthesis and methemoglobinemia-inducing properties of analogues of para-aminopropiophenone designed as humane rodenticides

artículo científico publicado en 2013

Synthesis and methemoglobinemia-inducing properties of benzocaine isosteres designed as humane rodenticides

artículo científico publicado en 2014

Thalidomide pharmacokinetics and metabolite formation in mice, rabbits, and multiple myeloma patients

artículo científico publicado en 2004

The bioactivation of amodiaquine by human polymorphonuclear leucocytes in vitro: Chemical mechanisms and the effects of fluorine substitution

artículo científico publicado en 1995

The combined impact of CYP2C19 and CYP2B6 pharmacogenetics on cyclophosphamide bioactivation

artículo científico publicado en 2010

The effect of 2,2'-substitution on the metabolism and toxicity of dapsone in vitro and in vivo.

artículo científico publicado en 1998

The importance of correct assignment of CYP2B6 genetic variants with respect to cyclophosphamide metabolizer status ⬇️

artículo científico publicado el 1 de abril de 2011

UDP-glucuronosyltransferase activity, expression and cellular localization in human placenta at term

artículo científico publicado en 2002

Use of a metabolic inhibitor to reduce dapsone-dependent haematological toxicity

artículo científico publicado en 1992

Validation of an LC-MS method for the detection and quantification of BZP and TFMPP and their hydroxylated metabolites in human plasma and its application to the pharmacokinetic study of TFMPP in humans

artículo científico publicado en 2010

Varenicline improves motor and cognitive symptoms in early Huntington's disease

artículo científico publicado en 2016

Which CYP2B6 Variants Have Functional Consequences for Cyclophosphamide Bioactivation?

artículo científico publicado en 2011

Lista de obras de Malcolm D Tingle

3'-azido-3'-deoxythymidine (AZT) induces apoptosis and alters metabolic enzyme activity in human placenta

A difference between the rat and mouse in the pharmacokinetic interaction of 5,6-dimethylxanthenone-4-acetic acid with thalidomide

A systematic review of clozapine-induced myocarditis.

Abstract 2532: Triethylenetetramine metabolism and its implication in cancer chemotherapy

Adenosine amine congener as a cochlear rescue agent

Aerobic 2- and 4-nitroreduction of CB 1954 by human liver

An Investigation into the Haematological Toxicity of Structural Analogues of Dapsone In-vivo and In-vitro

An investigation of the formation of cytotoxic, genotoxic, protein-reactive and stable metabolites from naphthalene by human liver microsomes

Antimutagenic effects of wheat bran diet through modification of xenobiotic metabolising enzymes

Ascending single dose pharmacokinetics of cytisine in healthy adult smokers

Bioactivation and inactivation of aflatoxin B1 by human, mouse and rat liver preparations: effect on SCE in human mononuclear leucocytes.

COMPARATIVE PROTEIN BINDING, STABILITY AND DEGRADATION OF SATRAPLATIN, JM118 AND CISPLATIN IN HUMAN PLASMAIN VITRO

Circulating microRNA as biomarkers of clozapine-induced cardiotoxicity

Determination of two major metabolites of the novel anti-tumour agent 5,6-dimethylxanthenone-4-acetic acid in hepatic microsomal incubations by high-performance liquid chromatography with fluorescence detection

Drug-protein conjugates—XIV

Effects of anticancer drugs on the metabolism of the anticancer drug 5,6-dimethylxanthenone-4-acetic (DMXAA) by human liver microsomes

Evaluation of the generation of genotoxic and cytotoxic metabolites of benzo[a]pyrene, aflatoxin B1, naphthalene and tamoxifen using human liver microsomes and human lymphocytes

Gender differences in the metabolism and pharmacokinetics of the experimental anticancer agent 5,6-dimethylxanthenone-4-acetic acid (DMXAA).

Glucuronidation of anticancer prodrug PR-104A: species differences, identification of human UDP-glucuronosyltransferases, and implications for therapy

Gonadal influence on the metabolism and haematological toxicity of dapsone in the rat.

Hepatic nitroreduction, toxicity and toxicokinetics of the anti-tumour prodrug CB 1954 in mouse and rat

Human placental glucuronidation and transport of 3'azido-3'-deoxythymidine and uridine diphosphate glucuronic acid

Identification and reactivity of the major metabolite (beta-1-glucuronide) of the anti-tumour agent 5,6-dimethylxanthenone-4-acetic acid (DMXAA) in humans

In vitro and in vivo kinetic interactions of the antitumour agent 5,6-dimethylxanthenone-4-acetic acid with thalidomide and diclofenac

In vitro metabolism of norbormide in rat, mouse and guinea pig liver preparations

In vivo metabolism of norbormide in rats and mice

Indirect regulation of CYP2C19 gene expression via DNA methylation.

Influence of mustard group structure on pathways of in vitro metabolism of anticancer N-(2-hydroxyethyl)-3,5-dinitrobenzamide 2-mustard prodrugs

Inhibition of Dapsone-Induced Methaemoglobinaemia by Cimetidine in the Rat During Chronic Dapsone Administration

Inhibition of Dapsone-induced Methaemoglobinaemia by Cimetidine in the Presence of Trimethoprim in the Rat

Measuring antibiotic levels and their relationship with the microbiome in chronic rhinosinusitis

Metabolic interactions with piperazine-based 'party pill' drugs

Metabolism of praziquantel in kingfish Seriola lalandi

Metabolism of thalidomide in liver microsomes of mice, rabbits, and humans

Oral antibiotics used in the treatment of chronic rhinosinusitis have limited penetration into the sinonasal mucosa: a randomized trial

Pharmacokinetic Properties of Adenosine Amine Congener in Cochlear Perilymph after Systemic Administration

Pharmacokinetics and in vivo chemosuppressive activity studies on cryptolepine hydrochloride and cryptolepine hydrochloride-loaded gelatine nanoformulation designed for parenteral administration for the treatment of malaria

Pharmacokinetics of cytisine, an α4β2nicotinic receptor partial agonist, in healthy smokers following a single dose

Rapid biotransformation of satraplatin by human red blood cells in vitro

Regulating new psychoactive drugs: innovation leading to compromise.

Reversible binding of the novel anti-tumour agent 5,6-dimethylxanthenone-4-acetic acid to plasma proteins and its distribution into blood cells in various species

Satraplatin activation by haemoglobin, cytochrome C and liver microsomes in vitro

Species differences in the metabolism of the antitumour agent 5,6-dimethylxanthenone-4-acetic acid in vitro: implications for prediction of metabolic interactions in vivo

Specific determination of intact cisplatin and monohydrated cisplatin in human plasma and culture medium ultrafiltrates using HPLC on-line with inductively coupled plasma mass spectrometry

Structural basis for the haemotoxicity of dapsone: the importance of the sulphonyl group

Synthesis and methemoglobinemia-inducing properties of analogues of para-aminopropiophenone designed as humane rodenticides

Synthesis and methemoglobinemia-inducing properties of benzocaine isosteres designed as humane rodenticides

Thalidomide pharmacokinetics and metabolite formation in mice, rabbits, and multiple myeloma patients

The bioactivation of amodiaquine by human polymorphonuclear leucocytes in vitro: Chemical mechanisms and the effects of fluorine substitution

The combined impact of CYP2C19 and CYP2B6 pharmacogenetics on cyclophosphamide bioactivation

The effect of 2,2'-substitution on the metabolism and toxicity of dapsone in vitro and in vivo.

The importance of correct assignment of CYP2B6 genetic variants with respect to cyclophosphamide metabolizer status ⬇️

UDP-glucuronosyltransferase activity, expression and cellular localization in human placenta at term

Use of a metabolic inhibitor to reduce dapsone-dependent haematological toxicity

Validation of an LC-MS method for the detection and quantification of BZP and TFMPP and their hydroxylated metabolites in human plasma and its application to the pharmacokinetic study of TFMPP in humans

Varenicline improves motor and cognitive symptoms in early Huntington's disease

Which CYP2B6 Variants Have Functional Consequences for Cyclophosphamide Bioactivation?