Lista de obras - Kazuhiro Aoki - Dominio Público Uruguay

A microtubule-LUZP1 association around tight junction promotes epithelial cell apical constriction

artículo científico publicado en 2020

A novel red fluorescence dopamine biosensor selectively detects dopamine in the presence of norepinephrine in vitro

artículo científico publicado en 2021

A quantitative model of ERK MAP kinase phosphorylation in crowded media

artículo científico publicado en 2013

An essential role for the SHIP2-dependent negative feedback loop in neuritogenesis of nerve growth factor-stimulated PC12 cells

scientific journal article

Cell-to-Cell Heterogeneity in p38-Mediated Cross-Inhibition of JNK Causes Stochastic Cell Death

artículo científico publicado en 2018

Composite regulation of ERK activity dynamics underlying tumour-specific traits in the intestine.

artículo científico publicado en 2018

Control cell migration by engineering integrin ligand assembly

artículo científico publicado en 2022

Development of a FRET biosensor with high specificity for Akt.

artículo científico publicado en 2013

Development of an optimized backbone of FRET biosensors for kinases and GTPases

artículo científico publicado en 2011

Distinct predictive performance of Rac1 and Cdc42 in cell migration

artículo científico publicado en 2015

Dynamics of the Ras/ERK MAPK Cascade as Monitored by Fluorescent Probes

artículo científico publicado en 2006

ERK-Mediated Mechanochemical Waves Direct Collective Cell Polarization

scientific article published on 27 May 2020

Efficient synthesis of phycocyanobilin in mammalian cells for optogenetic control of cell signaling

artículo científico publicado en 2017

Engineering Orthogonal, Plasma Membrane-Specific SLIPT Systems for Multiplexed Chemical Control of Signaling Pathways in Living Single Cells

scientific article published on 20 March 2020

FRET imaging and statistical signal processing reveal positive and negative feedback loops regulating the morphology of randomly migrating HT-1080 cells.

artículo científico publicado en 2012

FRET imaging in nerve growth cones reveals a high level of RhoA activity within the peripheral domain

artículo científico publicado en 2005

Fluorescence resonance energy transfer based quantitative analysis of feedforward and feedback loops in epidermal growth factor receptor signaling and the sensitivity to molecular targeting drugs

artículo científico publicado en 2014

Fluorescence resonance energy transfer imaging of cell signaling from in vitro to in vivo: basis of biosensor construction, live imaging, and image processing

artículo científico publicado en 2013

GTP hydrolysis by the Rho family GTPase TC10 promotes exocytic vesicle fusion.

artículo científico publicado en 2006

Improved secretion of glycoproteins using an N-glycan-restricted passport sequence tag recognized by cargo receptor

scientific article published on 13 March 2020

Improvement of Phycocyanobilin Synthesis for Genetically Encoded Phytochrome-Based Optogenetics

artículo científico publicado en 2020

Improvement of the bioluminescence reporter system for real-time monitoring of circadian rhythms in the cyanobacterium Synechocystis sp. strain PCC 6803.

artículo científico publicado en 2005

Intercellular propagation of extracellular signal-regulated kinase activation revealed by in vivo imaging of mouse skin.

artículo científico publicado en 2015

Inverse tissue mechanics of cell monolayer expansion

artículo científico publicado en 2018

Live-cell Imaging with Genetically Encoded Protein Kinase Activity Reporters.

artículo científico publicado en 2018

Mechanism and role of localized activation of Rho-family GTPases in growth factor-stimulated fibroblasts and neuronal cells.

artículo científico publicado en 2005

Monitoring spatio-temporal regulation of Ras and Rho GTPase with GFP-based FRET probes.

artículo científico publicado en 2005

Multiple decisive phosphorylation sites for the negative feedback regulation of SOS1 via ERK.

artículo científico publicado en 2010

Multiplexed Fluorescence Imaging of ERK and Akt Activities and Cell-cycle Progression.

artículo científico publicado en 2016

On the Synchrony of Morphological and Molecular Signaling Events in Cell Migration

Phosphorylation and activation of the Rac1 and Cdc42 GEF Asef in A431 cells stimulated by EGF.

artículo científico publicado en 2008

Processive phosphorylation of ERK MAP kinase in mammalian cells

artículo científico publicado en 2011

Propagating Wave of ERK Activation Orients Collective Cell Migration.

artículo científico publicado en 2017

Quantification of dissociation constant in living cells by fluorescence cross-correlation spectroscopy

scientific article published on 01 February 2016

Quantification of local morphodynamics and local GTPase activity by edge evolution tracking

artículo científico publicado en 2008

Quantitative analysis of recombination between YFP and CFP genes of FRET biosensors introduced by lentiviral or retroviral gene transfer.

artículo científico publicado en 2015

Quantitative in vivo fluorescence cross-correlation analyses highlight the importance of competitive effects in the regulation of protein-protein interactions

artículo científico publicado en 2014

Ras and calcium signaling pathways converge at Raf1 via the Shoc2 scaffold protein

artículo científico publicado en 2010

Regulation of RalA GTPase by phosphatidylinositol 3-kinase as visualized by FRET probes

artículo científico publicado en 2006

SH3BP1, an exocyst-associated RhoGAP, inactivates Rac1 at the front to drive cell motility

artículo científico publicado en 2011

Single-cell quantification of the concentrations and dissociation constants of endogenous proteins

scientific article published on 09 February 2019

Spatio-temporal regulation of Rac1 and Cdc42 activity during nerve growth factor-induced neurite outgrowth in PC12 cells

artículo científico publicado en 2003

Spatiotemporal regulation of small GTPases as revealed by probes based on the principle of Förster Resonance Energy Transfer (FRET): Implications for signaling and pharmacology

artículo científico publicado en 2011

Stable expression of FRET biosensors: a new light in cancer research

artículo científico publicado en 2012

Stochastic ERK activation induced by noise and cell-to-cell propagation regulates cell density-dependent proliferation

artículo científico publicado en 2013

Synergistic antitumor effects of combination PI3K/mTOR and MEK inhibition (SAR245409 and pimasertib) in mucinous ovarian carcinoma cells by fluorescence resonance energy transfer imaging

scientific article published on 18 April 2016

The scaffold protein Shoc2/SUR-8 accelerates the interaction of Ras and Raf.

artículo científico publicado en 2010

Two New FRET Imaging Measures: Linearly Proportional to and Highly Contrasting the Fraction of Active Molecules

artículo científico publicado en 2016

Variegated RHOA mutations in adult T-cell leukemia/lymphoma.

artículo científico publicado en 2015

Visualization of Neuregulin 1 ectodomain shedding reveals its local processing in vitro and in vivo.

artículo científico publicado en 2016

Visualization of growth signal transduction cascades in living cells with genetically encoded probes based on Förster resonance energy transfer

artículo científico publicado en 2008

Visualization of small GTPase activity with fluorescence resonance energy transfer-based biosensors

artículo científico publicado en 2009

[Dynamics of Rho-family G proteins as visualized with FRET-based probes]

scientific article published on 01 August 2005

mTORC1 upregulation via ERK-dependent gene expression change confers intrinsic resistance to MEK inhibitors in oncogenic KRas-mutant cancer cells.

artículo científico publicado en 2015

Lista de obras de Kazuhiro Aoki

A microtubule-LUZP1 association around tight junction promotes epithelial cell apical constriction

A novel red fluorescence dopamine biosensor selectively detects dopamine in the presence of norepinephrine in vitro

A quantitative model of ERK MAP kinase phosphorylation in crowded media

An essential role for the SHIP2-dependent negative feedback loop in neuritogenesis of nerve growth factor-stimulated PC12 cells

Cell-to-Cell Heterogeneity in p38-Mediated Cross-Inhibition of JNK Causes Stochastic Cell Death

Composite regulation of ERK activity dynamics underlying tumour-specific traits in the intestine.

Control cell migration by engineering integrin ligand assembly

Development of a FRET biosensor with high specificity for Akt.

Development of an optimized backbone of FRET biosensors for kinases and GTPases

Distinct predictive performance of Rac1 and Cdc42 in cell migration

Dynamics of the Ras/ERK MAPK Cascade as Monitored by Fluorescent Probes

ERK-Mediated Mechanochemical Waves Direct Collective Cell Polarization

Efficient synthesis of phycocyanobilin in mammalian cells for optogenetic control of cell signaling

Engineering Orthogonal, Plasma Membrane-Specific SLIPT Systems for Multiplexed Chemical Control of Signaling Pathways in Living Single Cells

FRET imaging and statistical signal processing reveal positive and negative feedback loops regulating the morphology of randomly migrating HT-1080 cells.

FRET imaging in nerve growth cones reveals a high level of RhoA activity within the peripheral domain

Fluorescence resonance energy transfer based quantitative analysis of feedforward and feedback loops in epidermal growth factor receptor signaling and the sensitivity to molecular targeting drugs

Fluorescence resonance energy transfer imaging of cell signaling from in vitro to in vivo: basis of biosensor construction, live imaging, and image processing

GTP hydrolysis by the Rho family GTPase TC10 promotes exocytic vesicle fusion.

Improved secretion of glycoproteins using an N-glycan-restricted passport sequence tag recognized by cargo receptor

Improvement of Phycocyanobilin Synthesis for Genetically Encoded Phytochrome-Based Optogenetics

Improvement of the bioluminescence reporter system for real-time monitoring of circadian rhythms in the cyanobacterium Synechocystis sp. strain PCC 6803.

Intercellular propagation of extracellular signal-regulated kinase activation revealed by in vivo imaging of mouse skin.

Inverse tissue mechanics of cell monolayer expansion

Live-cell Imaging with Genetically Encoded Protein Kinase Activity Reporters.

Mechanism and role of localized activation of Rho-family GTPases in growth factor-stimulated fibroblasts and neuronal cells.

Monitoring spatio-temporal regulation of Ras and Rho GTPase with GFP-based FRET probes.

Multiple decisive phosphorylation sites for the negative feedback regulation of SOS1 via ERK.

Multiplexed Fluorescence Imaging of ERK and Akt Activities and Cell-cycle Progression.

On the Synchrony of Morphological and Molecular Signaling Events in Cell Migration

Phosphorylation and activation of the Rac1 and Cdc42 GEF Asef in A431 cells stimulated by EGF.

Processive phosphorylation of ERK MAP kinase in mammalian cells

Propagating Wave of ERK Activation Orients Collective Cell Migration.

Quantification of dissociation constant in living cells by fluorescence cross-correlation spectroscopy

Quantification of local morphodynamics and local GTPase activity by edge evolution tracking

Quantitative analysis of recombination between YFP and CFP genes of FRET biosensors introduced by lentiviral or retroviral gene transfer.

Quantitative in vivo fluorescence cross-correlation analyses highlight the importance of competitive effects in the regulation of protein-protein interactions

Ras and calcium signaling pathways converge at Raf1 via the Shoc2 scaffold protein

Regulation of RalA GTPase by phosphatidylinositol 3-kinase as visualized by FRET probes

SH3BP1, an exocyst-associated RhoGAP, inactivates Rac1 at the front to drive cell motility

Single-cell quantification of the concentrations and dissociation constants of endogenous proteins

Spatio-temporal regulation of Rac1 and Cdc42 activity during nerve growth factor-induced neurite outgrowth in PC12 cells

Spatiotemporal regulation of small GTPases as revealed by probes based on the principle of Förster Resonance Energy Transfer (FRET): Implications for signaling and pharmacology

Stable expression of FRET biosensors: a new light in cancer research

Stochastic ERK activation induced by noise and cell-to-cell propagation regulates cell density-dependent proliferation

Synergistic antitumor effects of combination PI3K/mTOR and MEK inhibition (SAR245409 and pimasertib) in mucinous ovarian carcinoma cells by fluorescence resonance energy transfer imaging

The scaffold protein Shoc2/SUR-8 accelerates the interaction of Ras and Raf.

Two New FRET Imaging Measures: Linearly Proportional to and Highly Contrasting the Fraction of Active Molecules

Variegated RHOA mutations in adult T-cell leukemia/lymphoma.

Visualization of Neuregulin 1 ectodomain shedding reveals its local processing in vitro and in vivo.

Visualization of growth signal transduction cascades in living cells with genetically encoded probes based on Förster resonance energy transfer

Visualization of small GTPase activity with fluorescence resonance energy transfer-based biosensors

[Dynamics of Rho-family G proteins as visualized with FRET-based probes]

mTORC1 upregulation via ERK-dependent gene expression change confers intrinsic resistance to MEK inhibitors in oncogenic KRas-mutant cancer cells.