Lista de obras - Alberto Corsini - Dominio Público Uruguay

2-Amino-3-(phenylsulfanyl)norbornane-2-carboxylate: an appealing scaffold for the design of Rac1-Tiam1 protein-protein interaction inhibitors

artículo científico publicado en 2014

27-Hydroxycholesterol modulation of low density lipoprotein metabolism in cultured human hepatic and extrahepatic cells

artículo científico publicado en 1993

Ability of the LDL receptor from several animal species to recognize the human apo B binding domain: studies with LDL from familial defective apo B-100.

artículo científico publicado en 1992

Acute heart failure in patients with acute aortic syndrome: pathophysiology and clinical-prognostic implications

artículo científico publicado en 2015

Ajoene, a garlic compound, inhibits protein prenylation and arterial smooth muscle cell proliferation.

artículo científico publicado en 2003

Aliskiren reduces prorenin receptor expression and activity in cultured human aortic smooth muscle cells

artículo científico publicado en 2011

An analysis of the management of cardiovascular risk factors in routine clinical practice in Italy: an overview of the main findings of the EFFECTUS study.

artículo científico publicado en 2011

Association of physicians’ accuracy in recording with quality of care in cardiovascular medicine

artículo científico publicado en 2009

Atorvastatin reduces long pentraxin 3 expression in vascular cells by inhibiting protein geranylgeranylation

artículo científico publicado en 2015

Autosomal recessive hypercholesterolemia in a Sicilian kindred harboring the 432insA mutation of the ARH gene

artículo científico publicado en 2003

Biomarkers for atherosclerosis: pathophysiological role and pharmacological modulation.

artículo científico publicado en 2006

Bococizumab for the treatment of hypercholesterolaemia

artículo científico publicado en 2017

Chemotactic effect of prorenin on human aortic smooth muscle cells: a novel function of the (pro)renin receptor.

artículo científico publicado en 2012

Cholesterol and mevalonic acid modulation in cell metabolism and multiplication

artículo científico publicado el 1 de diciembre de 1992

Cholesterol stimulation of HDL binding to human endothelial cells EAhy 926 and skin fibroblasts: evidence for a mechanism independent of cellular metabolism

artículo científico publicado en 1991

Clinical and biochemical characterisation of patients with autosomal recessive hypercholesterolemia (ARH)

artículo científico publicado en 2003

Colesevelam hydrochloride: usefulness of a specifically engineered bile acid sequestrant for lowering LDL-cholesterol.

artículo científico publicado en 2009

Current challenges and controversies in drug-induced liver injury.

artículo científico publicado en 2012

Direct effects of statins on the vascular wall

scientific article published on 01 May 1998

Direct vascular effects of HMG-CoA reductase inhibitors

artículo científico publicado en 1998

Do structural differences in statins correlate with clinical efficacy?

artículo científico publicado en 2010

Drug attrition during pre-clinical and clinical development: understanding and managing drug-induced cardiotoxicity.

artículo científico

Drug-drug interaction with statins.

artículo científico publicado en 2008

Drug-drug interactions with statins: will pitavastatin overcome the statins' Achilles' heel?

artículo científico publicado en 2011

Dysfunction of the cholesterol biosynthetic pathway in Huntington's disease.

artículo científico publicado en 2005

ETC-1002 (Bempedoic acid) for the management of hyperlipidemia: from preclinical studies to phase 3 trials

artículo científico publicado en 2019

Effect of S(-) perillic acid on protein prenylation and arterial smooth muscle cell proliferation.

artículo científico publicado en 2001

Effect of atherogenic lipoproteins on PAI-1 synthesis by endothelial cells ⬇️

artículo científico publicado el 1 de enero de 1993

Effect of the new HMG-CoA reductase inhibitor cerivastatin (BAY W 6228)on migration, proliferation and cholesterol synthesis in arterial myocytes

scientific article published on 01 January 1996

Effect of the new calcium antagonist lercanidipine and its enantiomers on the migration and proliferation of arterial myocytes

artículo científico publicado en 1996

Effect of the nifedipine-atenolol association on arterial myocyte migration and proliferation

scientific article published on 01 May 1993

Everolimus inhibits monocyte/macrophage migration in vitro and their accumulation in carotid lesions of cholesterol-fed rabbits.

artículo científico publicado en 2008

Experimental studies on the hypolipidemic activity of chloridarol

scientific article published on 01 February 1983

Fibrillar collagen inhibits cholesterol biosynthesis in human aortic smooth muscle cells.

artículo científico publicado en 2009

Fluid–Structure Computational Analysis to Investigate the Link between Early Atherogenic Events and the Hemodynamic Environment in an Experimental Model of Intimal Thickening

article published in 2012

Fluvastatin synergistically improves the antiproliferative effect of everolimus on rat smooth muscle cells by altering p27Kip1/cyclin E expression

scientific journal article

Free cholesterol alters macrophage morphology and mobility by an ABCA1 dependent mechanism

artículo científico publicado en 2011

Global cardiovascular risk management in different Italian regions: An analysis of the evaluation of final feasible effect of control training and ultra sensitisation (EFFECTUS) educational program

artículo científico publicado en 2012

High density lipoproteins: physiopathology and clinical relevance

artículo científico publicado en 1992

Impact of diabetes mellitus on the clinical management of global cardiovascular risk: analysis of the results of the Evaluation of Final Feasible Effect of Control Training and Ultra Sensitization (EFFECTUS) educational program

artículo científico publicado en 2011

Impact of physicians' age on the clinical management of global cardiovascular risk: analysis of the results of the Evaluation of Final Feasible Effect of Control Training and Ultra Sensitisation Educational Programme.

artículo científico publicado en 2011

Increased atherosclerosis and vascular inflammation in APP transgenic mice with apolipoprotein E deficiency.

artículo científico publicado en 2009

Influence of trapidil and derivatives on cholesterol synthesis and esterification in cultured cells

artículo científico publicado en 1991

Inhibitory effect of PCSK9 on Abca1 protein expression and cholesterol efflux in macrophages

artículo científico publicado en 2016

Isothiazole dioxide derivative 6n inhibits vascular smooth muscle cell proliferation and protein farnesylation

scientific journal article

Isothiazoles. Part XV. A mild and efficient synthesis of new antiproliferative 5-sulfanylsubstituted 3-alkylaminoisothiazole 1,1-dioxides

artículo científico publicado en 2006

Lipid lowering drugs and inflammatory changes: an impact on cardiovascular outcomes?

artículo científico publicado en 2018

Multidimensional approach for the proper management of a complex chronic patient with chronic obstructive pulmonary disease.

artículo científico publicado en 2017

New Ras CAAX mimetics: design, synthesis, antiproliferative activity, and RAS prenylation inhibition

artículo científico publicado en 2009

New insights into the pharmacodynamic and pharmacokinetic properties of statins.

artículo científico publicado en 1999

Nitric oxide-donating atorvastatin attenuates neutrophil recruitment during vascular inflammation independent of changes in plasma cholesterol

artículo científico publicado en 2013

Nutraceuticals and functional foods for the control of plasma cholesterol levels. An intersociety position paper

article

Oxidized LDL-dependent pathway as new pathogenic trigger in arrhythmogenic cardiomyopathy

artículo científico publicado en 2021

PCSK9 antagonists and inflammation

artículo científico publicado en 2017

PCSK9 knock-out mice are protected from neointimal formation in response to perivascular carotid collar placement

artículo científico publicado en 2016

PPAR alpha inhibits vascular smooth muscle cell proliferation underlying intimal hyperplasia by inducing the tumor suppressor p16INK4a

artículo científico publicado en 2005

Peptidomimetic inhibitors of farnesyltransferase with high in vitro activity and significant cellular potency

artículo científico publicado en 2007

Perivascular carotid collar placement induces neointima formation and outward arterial remodeling in mice independent of apolipoprotein E deficiency or Western-type diet feeding

artículo científico publicado en 2007

Pharmacokinetic interactions between statins and fibrates

artículo científico publicado en 2005

Pharmacokinetics interactions of monoclonal antibodies.

artículo científico publicado en 2016

Pharmacological interactions of statins.

artículo científico publicado en 2002

Pharmacology of competitive inhibitors of HMG-CoA reductase.

artículo científico publicado en 1995

Pharmacology of dipeptidyl peptidase-4 inhibitors: similarities and differences.

artículo científico

Picotamide, an antithromboxane agent, inhibits the migration and proliferation of arterial myocytes ⬇️

artículo científico publicado el 14 de agosto de 1998

Potential statin drug interactions in elderly patients: a review

scientific article published on 10 September 2020

Proprotein convertase subtilisin kexin type 9 (PCSK9) secreted by cultured smooth muscle cells reduces macrophages LDLR levels ⬇️

artículo científico publicado el 25 de noviembre de 2011

Proprotein convertase subtilisin kexin type 9 and high-density lipoprotein metabolism: experimental animal models and clinical evidence

artículo científico

Purification and In Vitro Evaluation of an Anti-HER2 Affibody-Monomethyl Auristatin E Conjugate in HER2-Positive Cancer Cells

artículo científico publicado en 2021

Raloxifene elicits combined rapid vasorelaxation and long-term anti-inflammatory actions in rat aorta.

artículo científico publicado en 2006

Raloxifene inhibits matrix metalloproteinases expression and activity in macrophages and smooth muscle cells.

artículo científico publicado en 2007

Reversible and non-reversible cardiovascular risk in patients treated with lipid-lowering therapy: Analysis of SEAS and JUPITER trials ⬇️

artículo científico publicado el 3 de julio de 2010

Risk for myopathy with statin therapy in high-risk patients.

artículo científico publicado en 2003

Rosuvastatin displays anti-atherothrombotic and anti-inflammatory properties in apoE-deficient mice

artículo científico publicado en 2007

Serum from hypercholesterolemic patients treated with atorvastatin or simvastatin inhibits cultured human smooth muscle cell proliferation

artículo científico publicado en 2007

Simvastatin but not pravastatin has a direct inhibitory effect on rat and human myocyte proliferation

artículo científico publicado en 1992

Simvastatin reduces MMP1 expression in human smooth muscle cells cultured on polymerized collagen by inhibiting Rac1 activation

scientific article published on 15 February 2007

Statin drug interactions and related adverse reactions

artículo científico publicado en 2012

Statin drug interactions and related adverse reactions: an update

artículo científico publicado en 2017

Statin-related muscle complaints: an underestimated risk

scientific article published on 01 December 2005

Statins effect on smooth muscle cell proliferation.

artículo científico publicado en 2004

Synthesis, structural, and biological evaluation of bis-heteroarylmaleimides and bis-heterofused imides

artículo científico publicado en 2011

Synthetic peptides containing a conserved sequence motif of the Id protein family modulate vascular smooth muscle cell phenotype

artículo científico publicado en 2009

The role of mitochondria in statin-induced myopathy

artículo científico

The safety of HMG-CoA reductase inhibitors in special populations at high cardiovascular risk

artículo científico publicado el 1 de mayo de 2003

Thiazole- and imidazole-containing peptidomimetic inhibitors of protein farnesyltransferase

artículo científico publicado en 2011

Treatment of dyslipidemia in kidney transplantation

scientific article published on 02 March 2020

Upregulation of lectin-like oxidized low density lipoprotein receptor 1 (LOX-1) expression in human endothelial cells by modified high density lipoproteins

artículo científico publicado en 2012

Upregulation of lectin-like oxidized low-density lipoprotein receptor-1 (LOX-1) by 15-lipoxygenase-modified LDL in endothelial cells

artículo científico publicado en 2010

Virtual screening approach for the identification of new Rac1 inhibitors

artículo científico publicado en 2009

[Polytherapy and polypharmacy in elderly patients with chronic heart failure]

artículo científico publicado en 2013

Lista de obras de Alberto Corsini

2-Amino-3-(phenylsulfanyl)norbornane-2-carboxylate: an appealing scaffold for the design of Rac1-Tiam1 protein-protein interaction inhibitors

27-Hydroxycholesterol modulation of low density lipoprotein metabolism in cultured human hepatic and extrahepatic cells

Ability of the LDL receptor from several animal species to recognize the human apo B binding domain: studies with LDL from familial defective apo B-100.

Acute heart failure in patients with acute aortic syndrome: pathophysiology and clinical-prognostic implications

Ajoene, a garlic compound, inhibits protein prenylation and arterial smooth muscle cell proliferation.

Aliskiren reduces prorenin receptor expression and activity in cultured human aortic smooth muscle cells

An analysis of the management of cardiovascular risk factors in routine clinical practice in Italy: an overview of the main findings of the EFFECTUS study.

Association of physicians’ accuracy in recording with quality of care in cardiovascular medicine

Atorvastatin reduces long pentraxin 3 expression in vascular cells by inhibiting protein geranylgeranylation

Autosomal recessive hypercholesterolemia in a Sicilian kindred harboring the 432insA mutation of the ARH gene

Biomarkers for atherosclerosis: pathophysiological role and pharmacological modulation.

Bococizumab for the treatment of hypercholesterolaemia

Chemotactic effect of prorenin on human aortic smooth muscle cells: a novel function of the (pro)renin receptor.

Cholesterol and mevalonic acid modulation in cell metabolism and multiplication

Cholesterol stimulation of HDL binding to human endothelial cells EAhy 926 and skin fibroblasts: evidence for a mechanism independent of cellular metabolism

Clinical and biochemical characterisation of patients with autosomal recessive hypercholesterolemia (ARH)

Colesevelam hydrochloride: usefulness of a specifically engineered bile acid sequestrant for lowering LDL-cholesterol.

Current challenges and controversies in drug-induced liver injury.

Direct effects of statins on the vascular wall

Direct vascular effects of HMG-CoA reductase inhibitors

Do structural differences in statins correlate with clinical efficacy?

Drug attrition during pre-clinical and clinical development: understanding and managing drug-induced cardiotoxicity.

Drug-drug interaction with statins.

Drug-drug interactions with statins: will pitavastatin overcome the statins' Achilles' heel?

Dysfunction of the cholesterol biosynthetic pathway in Huntington's disease.

ETC-1002 (Bempedoic acid) for the management of hyperlipidemia: from preclinical studies to phase 3 trials

Effect of S(-) perillic acid on protein prenylation and arterial smooth muscle cell proliferation.

Effect of atherogenic lipoproteins on PAI-1 synthesis by endothelial cells ⬇️

Effect of the new HMG-CoA reductase inhibitor cerivastatin (BAY W 6228)on migration, proliferation and cholesterol synthesis in arterial myocytes

Effect of the new calcium antagonist lercanidipine and its enantiomers on the migration and proliferation of arterial myocytes

Effect of the nifedipine-atenolol association on arterial myocyte migration and proliferation

Everolimus inhibits monocyte/macrophage migration in vitro and their accumulation in carotid lesions of cholesterol-fed rabbits.

Experimental studies on the hypolipidemic activity of chloridarol

Fibrillar collagen inhibits cholesterol biosynthesis in human aortic smooth muscle cells.

Fluid–Structure Computational Analysis to Investigate the Link between Early Atherogenic Events and the Hemodynamic Environment in an Experimental Model of Intimal Thickening

Fluvastatin synergistically improves the antiproliferative effect of everolimus on rat smooth muscle cells by altering p27Kip1/cyclin E expression

Free cholesterol alters macrophage morphology and mobility by an ABCA1 dependent mechanism

Global cardiovascular risk management in different Italian regions: An analysis of the evaluation of final feasible effect of control training and ultra sensitisation (EFFECTUS) educational program

High density lipoproteins: physiopathology and clinical relevance

Impact of diabetes mellitus on the clinical management of global cardiovascular risk: analysis of the results of the Evaluation of Final Feasible Effect of Control Training and Ultra Sensitization (EFFECTUS) educational program

Impact of physicians' age on the clinical management of global cardiovascular risk: analysis of the results of the Evaluation of Final Feasible Effect of Control Training and Ultra Sensitisation Educational Programme.

Increased atherosclerosis and vascular inflammation in APP transgenic mice with apolipoprotein E deficiency.

Influence of trapidil and derivatives on cholesterol synthesis and esterification in cultured cells

Inhibitory effect of PCSK9 on Abca1 protein expression and cholesterol efflux in macrophages

Isothiazole dioxide derivative 6n inhibits vascular smooth muscle cell proliferation and protein farnesylation

Isothiazoles. Part XV. A mild and efficient synthesis of new antiproliferative 5-sulfanylsubstituted 3-alkylaminoisothiazole 1,1-dioxides

Lipid lowering drugs and inflammatory changes: an impact on cardiovascular outcomes?

Multidimensional approach for the proper management of a complex chronic patient with chronic obstructive pulmonary disease.

New Ras CAAX mimetics: design, synthesis, antiproliferative activity, and RAS prenylation inhibition

New insights into the pharmacodynamic and pharmacokinetic properties of statins.

Nitric oxide-donating atorvastatin attenuates neutrophil recruitment during vascular inflammation independent of changes in plasma cholesterol

Nutraceuticals and functional foods for the control of plasma cholesterol levels. An intersociety position paper

Oxidized LDL-dependent pathway as new pathogenic trigger in arrhythmogenic cardiomyopathy

PCSK9 antagonists and inflammation

PCSK9 knock-out mice are protected from neointimal formation in response to perivascular carotid collar placement

PPAR alpha inhibits vascular smooth muscle cell proliferation underlying intimal hyperplasia by inducing the tumor suppressor p16INK4a

Peptidomimetic inhibitors of farnesyltransferase with high in vitro activity and significant cellular potency

Perivascular carotid collar placement induces neointima formation and outward arterial remodeling in mice independent of apolipoprotein E deficiency or Western-type diet feeding

Pharmacokinetic interactions between statins and fibrates

Pharmacokinetics interactions of monoclonal antibodies.

Pharmacological interactions of statins.

Pharmacology of competitive inhibitors of HMG-CoA reductase.

Pharmacology of dipeptidyl peptidase-4 inhibitors: similarities and differences.

Picotamide, an antithromboxane agent, inhibits the migration and proliferation of arterial myocytes ⬇️

Potential statin drug interactions in elderly patients: a review

Proprotein convertase subtilisin kexin type 9 (PCSK9) secreted by cultured smooth muscle cells reduces macrophages LDLR levels ⬇️

Proprotein convertase subtilisin kexin type 9 and high-density lipoprotein metabolism: experimental animal models and clinical evidence

Purification and In Vitro Evaluation of an Anti-HER2 Affibody-Monomethyl Auristatin E Conjugate in HER2-Positive Cancer Cells

Raloxifene elicits combined rapid vasorelaxation and long-term anti-inflammatory actions in rat aorta.

Raloxifene inhibits matrix metalloproteinases expression and activity in macrophages and smooth muscle cells.

Reversible and non-reversible cardiovascular risk in patients treated with lipid-lowering therapy: Analysis of SEAS and JUPITER trials ⬇️

Risk for myopathy with statin therapy in high-risk patients.

Rosuvastatin displays anti-atherothrombotic and anti-inflammatory properties in apoE-deficient mice

Serum from hypercholesterolemic patients treated with atorvastatin or simvastatin inhibits cultured human smooth muscle cell proliferation

Simvastatin but not pravastatin has a direct inhibitory effect on rat and human myocyte proliferation

Simvastatin reduces MMP1 expression in human smooth muscle cells cultured on polymerized collagen by inhibiting Rac1 activation

Statin drug interactions and related adverse reactions

Statin drug interactions and related adverse reactions: an update

Statin-related muscle complaints: an underestimated risk