Lista de obras - Jae-Kyung Jung - Dominio Público Uruguay

(E)-2-methoxy-4-(3-(4-methoxyphenyl)prop-1-en-1-yl)phenol suppresses ovarian cancer cell growth via inhibition of ERK and STAT3.

artículo científico publicado en 2017

4-O-methylhonokiol attenuated memory impairment through modulation of oxidative damage of enzymes involving amyloid-β generation and accumulation in a mouse model of Alzheimer's disease

artículo científico publicado en 2011

4-O-methylhonokiol attenuated β-amyloid-induced memory impairment through reduction of oxidative damages via inactivation of p38 MAP kinase

artículo científico publicado en 2010

4-O-methylhonokiol inhibits colon tumor growth via p21-mediated suppression of NF-κB activity.

artículo científico publicado en 2011

4-O-methylhonokiol, a PPARγ agonist, inhibits prostate tumour growth: p21-mediated suppression of NF-κB activity.

artículo científico publicado en 2013

ALK inhibitors of bis-ortho-alkoxy-para-piperazinesubstituted-pyrimidines and -triazines for cancer treatment

artículo científico publicado en 2014

An efficient synthetic protocol for amide derivatives of Boc-2-aminoisobutyrate

scientific article published on 24 February 2018

Anti-Inflammatory and Anti-Migratory Activities of Isoquinoline-1-Carboxamide Derivatives in LPS-Treated BV2 Microglial Cells via Inhibition of MAPKs/NF-κB Pathway

artículo científico publicado en 2020

Anti-amyloidogenic effect of thiacremonone through anti-inflamation in vitro and in vivo models.

artículo científico

Anti-cancer effect of thiacremonone through down regulation of peroxiredoxin 6

artículo científico publicado en 2014

Anti-platelet activity of diacetylated obovatol through regulating cyclooxygenase and lipoxygenase activities

artículo científico publicado en 2012

Antioxidant and Anti-inflammatory Activities of N-((3,4-Dihydro-2H-benzo[h]chromene-2-yl)methyl)-4-methoxyaniline in LPS-Induced BV2 Microglial Cells.

artículo científico publicado en 2015

Anxiolytic-Like Effects of 4-O-Methylhonokiol Isolated from Magnolia officinalis Through Enhancement of GABAergic Transmission and Chloride Influx ⬇️

artículo científico publicado el 18 de abril de 2011

Asymmetric total synthesis of bacillariolide III, a marine oxylipin

scientific article published on 01 February 2004

Caffeic Acid Cyclohexylamide Rescues Lethal Inflammation in Septic Mice through Inhibition of IκB Kinase in Innate Immune Process.

artículo científico publicado en 2017

Characterization of fimasartan metabolites in human liver microsomes and human plasma.

artículo científico publicado en 2015

Concise Synthesis of Broussonone A

scientific article published on 02 September 2015

Concise synthesis of Obovatol: Chemoselective ortho-bromination of phenol and survey of Cu-catalyzed diaryl ether couplings

artículo científico publicado en 2008

Design and synthesis of 2,3-dihydro- and 5-chloro-2,3-dihydro-naphtho-[1,2-b]furan-2-carboxylic acid N-(substitutedphenyl)amide analogs and their biological activities as inhibitors of NF-κB activity and anticancer agents.

artículo científico publicado en 2016

Design and synthesis of 3,4-dihydro-2H-benzo[h]chromene derivatives as potential NF-κB inhibitors

artículo científico publicado en 2014

Design and synthesis of 4-O-methylhonokiol analogs as inhibitors of cyclooxygenase-2 (COX-2) and PGF1 production ⬇️

artículo científico publicado el 24 de marzo de 2012

Design, synthesis and biological evaluation of 1,3-diphenylbenzo[f][1,7]naphthyrdines.

artículo científico publicado en 2017

Design, synthesis, and biological evaluation of benzofuran- and 2,3-dihydrobenzofuran-2-carboxylic acid N-(substituted)phenylamide derivatives as anticancer agents and inhibitors of NF-κB.

artículo científico publicado en 2015

Development of 13H-benzo[f]chromeno[4,3-b][1,7]naphthyridines and their salts as potent cytotoxic agents and topoisomerase I/IIα inhibitors

scientific article published on 18 September 2018

Expedient synthesis of chiral homoallylamines via N,O-acetal TMS ethers and its application

artículo científico publicado el 13 de octubre de 2011

Functional divergency oriented synthesis of azoninones as the key intermediates for bioactive indolizidine alkaloids analogs.

artículo científico publicado en 2004

IRAK4 as a molecular target in the amelioration of innate immunity-related endotoxic shock and acute liver injury by chlorogenic acid

artículo científico publicado en 2014

Inhibitory effects of OD 78 [3-(4-bromo-phenoxy)-4,5-dihydroxybenzoic acid-methyl ester] on the proliferation and migration of TNF-α-induced rat aortic smooth muscle cells

artículo científico publicado en 2011

JJK694, a synthesized obovatol derivative, inhibits platelet activation by suppressing cyclooxygenase and lipoxygenase activities

artículo científico publicado en 2012

JY0691, a newly synthesized obovatol derivative, inhibits cell cycle progression of rat aortic smooth muscle cells through up-regulation of p21(cip1).

artículo científico publicado en 2009

Myeloid differentiation 2 as a therapeutic target of inflammatory disorders ⬇️

artículo científico publicado el 19 de noviembre de 2011

Neuroprotective and antioxidant effects of novel benzofuran-2-carboxamide derivatives.

artículo científico publicado en 2015

Novel NF-κB inhibitors: a patent review (2011 - 2014).

artículo científico publicado en 2015

Nuclear factor-kappa B inhibitors; a patent review (2006-2010).

artículo científico

Obovatol attenuates LPS-induced memory impairments in mice via inhibition of NF-κB signaling pathway

artículo científico publicado en 2011

Obovatol improves cognitive functions in animal models for Alzheimer's disease.

artículo científico publicado en 2012

Pharmacokinetics and metabolism of 4-O-methylhonokiol in rats

artículo científico publicado en 2013

Piperlongumine inhibits lung tumor growth via inhibition of nuclear factor kappa B signaling pathway

artículo científico publicado en 2016

Pyrrolidinone diterpenoid from Isodon excisus and inhibition of nitric oxide production in lipopolysaccharide-induced macrophage RAW264.7 cells ⬇️

artículo científico publicado el 25 de noviembre de 2010

Recent Advances and Challenges in Controlling the Spatiotemporal Release of Combinatorial Anticancer Drugs from Nanoparticles

artículo científico publicado en 2020

Simultaneous determination of loxoprofen and its diastereomeric alcohol metabolites in human plasma and urine by a simple HPLC-UV detection method

artículo científico publicado en 2001

Stereoselective formation of N-acyliminium ion via chiral N,O-acetal TMS ether and its application to the synthesis of beta-amino acids

artículo científico publicado en 2003

Stereoselective synthesis of (E)- and (Z)-enol ethers from beta-amino aldehydes

artículo científico publicado en 2007

Structure-activity relationship of indoline-2-carboxylic acid N-(substituted)phenylamide derivatives.

artículo científico publicado en 2010

Structure-activity relationships of 6-hydroxy-7-methoxychroman-2-carboxylic acid N-(substituted)phenylamides as inhibitors of nuclear factor-kappaB activation.

artículo científico publicado en 2007

Synthesis and anti-neuroinflammatory activity of N-heterocyclic analogs based on natural biphenyl-neolignan honokiol

artículo científico publicado en 2018

Synthesis and anti-platelet activity of obovatol derivatives

artículo científico publicado en 2011

Synthesis and biological evaluation of caffeic acid derivatives as potent inhibitors of α-MSH-stimulated melanogenesis.

artículo científico publicado en 2017

Synthesis and biological evaluation of thiazole derivatives as GPR119 agonists

artículo científico publicado en 2017

Synthesis and cytotoxic activities of 2-alkyl-2,3-dihydro-1H-2,6,9-triazacyclopenta[b]anthracene-5,10-diones.

artículo científico publicado en 2008

Synthesis and evaluation of 6-hydroxy-7-methoxy-4-chromanone- and chroman-2-carboxamides as antioxidants

artículo científico publicado en 2005

Synthesis and evaluation of antitumor activity of novel 1,4-naphthoquinone derivatives (IV).

artículo científico publicado en 2006

Synthesis and in Vitro cytotoxic activities of 2-alkyl-2,3-dihydro-1H-2,6-diazacyclopenta[b]anthracene-5,10-diones

artículo científico publicado en 2010

Synthesis and in vitro evaluation of 7-dialkylaminomethylbenzo[g]quinoxaline-5,10-diones

artículo científico publicado en 2004

Synthesis of 6-hydroxy-7-methoxy-4-oxo-4H-chromene-2-carboxylic acid N-alkyl amides and their antioxidant activity

artículo científico publicado en 2006

Synthesis of 7-hydroxy-4-oxo-4H-chromene- and 7-hydroxychroman-2-carboxylic acid N-alkyl amides and their antioxidant activities.

artículo científico publicado en 2006

Synthesis of N-arylindazole-3-carboxamide and N-benzoylindazole derivatives and their evaluation against α-MSH-stimulated melanogenesis

scientific article published on 01 August 2019

Synthesis of chroman-2-carboxylic acid N-(substituted)phenylamides and their inhibitory effect on nuclear factor-kappaB (NF-kappaB) activation.

artículo científico publicado en 2008

Synthesis of xanthone derivatives based on α-mangostin and their biological evaluation for anti-cancer agents.

artículo científico publicado en 2014

Synthesis, biological evaluation, and metabolic stability of chlorogenic acid derivatives possessing thiazole as potent inhibitors of α-MSH-stimulated melanogenesis

artículo científico publicado en 2017

Terpene alcohols inhibit de novo sphingolipid biosynthesis.

artículo científico publicado en 2012

The new 4-O-methylhonokiol analog GS12021 inhibits inflammation and macrophage chemotaxis: role of AMP-activated protein kinase α activation.

artículo científico publicado en 2015

The p21-activated kinase 4-Slug transcription factor axis promotes epithelial-mesenchymal transition and worsens prognosis in prostate cancer.

artículo científico publicado en 2018

The versatile conversion of acyclic amides to alpha-alkylated amines

scientific article published on 01 May 2002

Therapeutic applications of compounds in the Magnolia family ⬇️

artículo científico publicado el 26 de enero de 2011

Total synthesis of (+)-Brefeldin A.

artículo científico publicado en 2002

Total synthesis of anti-HIV agent chloropeptin I.

artículo científico publicado en 2003

Transition metal-free synthesis of quinazolinones using dimethyl sulfoxide as a synthon

scientific article published on 27 August 2019

Validation of cyclooxygenase-2 as a direct anti-inflammatory target of 4-O-methylhonokiol in zymosan-induced animal models

artículo científico publicado en 2014

Lista de obras de Jae-Kyung Jung

(E)-2-methoxy-4-(3-(4-methoxyphenyl)prop-1-en-1-yl)phenol suppresses ovarian cancer cell growth via inhibition of ERK and STAT3.

4-O-methylhonokiol attenuated memory impairment through modulation of oxidative damage of enzymes involving amyloid-β generation and accumulation in a mouse model of Alzheimer's disease

4-O-methylhonokiol attenuated β-amyloid-induced memory impairment through reduction of oxidative damages via inactivation of p38 MAP kinase

4-O-methylhonokiol inhibits colon tumor growth via p21-mediated suppression of NF-κB activity.

4-O-methylhonokiol, a PPARγ agonist, inhibits prostate tumour growth: p21-mediated suppression of NF-κB activity.

ALK inhibitors of bis-ortho-alkoxy-para-piperazinesubstituted-pyrimidines and -triazines for cancer treatment

An efficient synthetic protocol for amide derivatives of Boc-2-aminoisobutyrate

Anti-Inflammatory and Anti-Migratory Activities of Isoquinoline-1-Carboxamide Derivatives in LPS-Treated BV2 Microglial Cells via Inhibition of MAPKs/NF-κB Pathway

Anti-amyloidogenic effect of thiacremonone through anti-inflamation in vitro and in vivo models.

Anti-cancer effect of thiacremonone through down regulation of peroxiredoxin 6

Anti-platelet activity of diacetylated obovatol through regulating cyclooxygenase and lipoxygenase activities

Antioxidant and Anti-inflammatory Activities of N-((3,4-Dihydro-2H-benzo[h]chromene-2-yl)methyl)-4-methoxyaniline in LPS-Induced BV2 Microglial Cells.

Anxiolytic-Like Effects of 4-O-Methylhonokiol Isolated from Magnolia officinalis Through Enhancement of GABAergic Transmission and Chloride Influx ⬇️

Asymmetric total synthesis of bacillariolide III, a marine oxylipin

Caffeic Acid Cyclohexylamide Rescues Lethal Inflammation in Septic Mice through Inhibition of IκB Kinase in Innate Immune Process.

Characterization of fimasartan metabolites in human liver microsomes and human plasma.

Concise Synthesis of Broussonone A

Concise synthesis of Obovatol: Chemoselective ortho-bromination of phenol and survey of Cu-catalyzed diaryl ether couplings

Design and synthesis of 2,3-dihydro- and 5-chloro-2,3-dihydro-naphtho-[1,2-b]furan-2-carboxylic acid N-(substitutedphenyl)amide analogs and their biological activities as inhibitors of NF-κB activity and anticancer agents.

Design and synthesis of 3,4-dihydro-2H-benzo[h]chromene derivatives as potential NF-κB inhibitors

Design and synthesis of 4-O-methylhonokiol analogs as inhibitors of cyclooxygenase-2 (COX-2) and PGF1 production ⬇️

Design, synthesis and biological evaluation of 1,3-diphenylbenzo[f][1,7]naphthyrdines.

Design, synthesis, and biological evaluation of benzofuran- and 2,3-dihydrobenzofuran-2-carboxylic acid N-(substituted)phenylamide derivatives as anticancer agents and inhibitors of NF-κB.

Development of 13H-benzo[f]chromeno[4,3-b][1,7]naphthyridines and their salts as potent cytotoxic agents and topoisomerase I/IIα inhibitors

Expedient synthesis of chiral homoallylamines via N,O-acetal TMS ethers and its application

Functional divergency oriented synthesis of azoninones as the key intermediates for bioactive indolizidine alkaloids analogs.

IRAK4 as a molecular target in the amelioration of innate immunity-related endotoxic shock and acute liver injury by chlorogenic acid

Inhibitory effects of OD 78 [3-(4-bromo-phenoxy)-4,5-dihydroxybenzoic acid-methyl ester] on the proliferation and migration of TNF-α-induced rat aortic smooth muscle cells

JJK694, a synthesized obovatol derivative, inhibits platelet activation by suppressing cyclooxygenase and lipoxygenase activities

JY0691, a newly synthesized obovatol derivative, inhibits cell cycle progression of rat aortic smooth muscle cells through up-regulation of p21(cip1).

Myeloid differentiation 2 as a therapeutic target of inflammatory disorders ⬇️

Neuroprotective and antioxidant effects of novel benzofuran-2-carboxamide derivatives.

Novel NF-κB inhibitors: a patent review (2011 - 2014).

Nuclear factor-kappa B inhibitors; a patent review (2006-2010).

Obovatol attenuates LPS-induced memory impairments in mice via inhibition of NF-κB signaling pathway

Obovatol improves cognitive functions in animal models for Alzheimer's disease.

Pharmacokinetics and metabolism of 4-O-methylhonokiol in rats

Piperlongumine inhibits lung tumor growth via inhibition of nuclear factor kappa B signaling pathway

Pyrrolidinone diterpenoid from Isodon excisus and inhibition of nitric oxide production in lipopolysaccharide-induced macrophage RAW264.7 cells ⬇️

Recent Advances and Challenges in Controlling the Spatiotemporal Release of Combinatorial Anticancer Drugs from Nanoparticles

Simultaneous determination of loxoprofen and its diastereomeric alcohol metabolites in human plasma and urine by a simple HPLC-UV detection method

Stereoselective formation of N-acyliminium ion via chiral N,O-acetal TMS ether and its application to the synthesis of beta-amino acids

Stereoselective synthesis of (E)- and (Z)-enol ethers from beta-amino aldehydes

Structure-activity relationship of indoline-2-carboxylic acid N-(substituted)phenylamide derivatives.

Structure-activity relationships of 6-hydroxy-7-methoxychroman-2-carboxylic acid N-(substituted)phenylamides as inhibitors of nuclear factor-kappaB activation.

Synthesis and anti-neuroinflammatory activity of N-heterocyclic analogs based on natural biphenyl-neolignan honokiol

Synthesis and anti-platelet activity of obovatol derivatives

Synthesis and biological evaluation of caffeic acid derivatives as potent inhibitors of α-MSH-stimulated melanogenesis.

Synthesis and biological evaluation of thiazole derivatives as GPR119 agonists

Synthesis and cytotoxic activities of 2-alkyl-2,3-dihydro-1H-2,6,9-triazacyclopenta[b]anthracene-5,10-diones.

Synthesis and evaluation of 6-hydroxy-7-methoxy-4-chromanone- and chroman-2-carboxamides as antioxidants

Synthesis and evaluation of antitumor activity of novel 1,4-naphthoquinone derivatives (IV).

Synthesis and in Vitro cytotoxic activities of 2-alkyl-2,3-dihydro-1H-2,6-diazacyclopenta[b]anthracene-5,10-diones

Synthesis and in vitro evaluation of 7-dialkylaminomethylbenzo[g]quinoxaline-5,10-diones

Synthesis of 6-hydroxy-7-methoxy-4-oxo-4H-chromene-2-carboxylic acid N-alkyl amides and their antioxidant activity

Synthesis of 7-hydroxy-4-oxo-4H-chromene- and 7-hydroxychroman-2-carboxylic acid N-alkyl amides and their antioxidant activities.

Synthesis of N-arylindazole-3-carboxamide and N-benzoylindazole derivatives and their evaluation against α-MSH-stimulated melanogenesis

Synthesis of chroman-2-carboxylic acid N-(substituted)phenylamides and their inhibitory effect on nuclear factor-kappaB (NF-kappaB) activation.

Synthesis of xanthone derivatives based on α-mangostin and their biological evaluation for anti-cancer agents.

Synthesis, biological evaluation, and metabolic stability of chlorogenic acid derivatives possessing thiazole as potent inhibitors of α-MSH-stimulated melanogenesis

Terpene alcohols inhibit de novo sphingolipid biosynthesis.

The new 4-O-methylhonokiol analog GS12021 inhibits inflammation and macrophage chemotaxis: role of AMP-activated protein kinase α activation.

The p21-activated kinase 4-Slug transcription factor axis promotes epithelial-mesenchymal transition and worsens prognosis in prostate cancer.

The versatile conversion of acyclic amides to alpha-alkylated amines

Therapeutic applications of compounds in the Magnolia family ⬇️

Total synthesis of (+)-Brefeldin A.

Total synthesis of anti-HIV agent chloropeptin I.

Transition metal-free synthesis of quinazolinones using dimethyl sulfoxide as a synthon

Validation of cyclooxygenase-2 as a direct anti-inflammatory target of 4-O-methylhonokiol in zymosan-induced animal models