Lista de obras - Angela Risch - Dominio Público Uruguay

A Genome-wide Association Study of Lung Cancer Identifies a Region of Chromosome 5p15 Associated with Risk for Adenocarcinoma

artículo científico publicado en 2011

A Novel Genetic Variant in Long Non-coding RNA Gene NEXN-AS1 is Associated with Risk of Lung Cancer

artículo científico publicado en 2016

A common coding variant in CASP8 is associated with breast cancer risk

article

A comprehensive study of polymorphisms inABCB1, ABCC2andABCG2and lung cancer chemotherapy response and prognosis

article

A genome-wide association study of lung cancer identifies a region of chromosome 5p15 associated with risk for adenocarcinoma

artículo científico publicado en 2009

A multiplex real-time PCR method for detection of GSTM1 and GSTT1 copy numbers

artículo científico publicado en 2008

A network-based kernel machine test for the identification of risk pathways in genome-wide association studies

artículo científico publicado en 2013

Arylarnine N-acetyltransferase as a potential biornarker in bladder cancer: fluorescent in situ hybridization and irnmunohistochernistry studies

artículo científico publicado en 1996

Association analysis of driver-gene related genetic variants identified novel lung cancer susceptibility loci with 20,871 lung cancer cases and 15,971 controls

scientific article published on 10 April 2020

Association between Adult Height and Risk of Colorectal, Lung, and Prostate Cancer: Results from Meta-analyses of Prospective Studies and Mendelian Randomization Analyses

artículo científico publicado en 2016

Association of metabolic gene polymorphisms with tobacco consumption in healthy controls

artículo científico publicado en 2004

Associations between genetic variants in mRNA splicing-related genes and risk of lung cancer: a pathway-based analysis from published GWASs

artículo científico publicado en 2017

CHRNA5 risk variant predicts delayed smoking cessation and earlier lung cancer diagnosis--a meta-analysis

artículo científico publicado en 2015

CYP450 polymorphisms as risk factors for early-onset lung cancer: gender-specific differences

artículo científico publicado en 2009

Cancer cell specific inhibition of Wnt/β-catenin signaling by forced intracellular acidification.

artículo científico publicado en 2018

Comparison of multiple DNA adduct types in tumor adjacent human lung tissue: effect of cigarette smoking

artículo científico publicado en 2002

Comparison of pathway analysis approaches using lung cancer GWAS data sets

artículo científico publicado en 2012

Copy number variations of GSTT1 and GSTM1, colorectal cancer risk and possible effect modification of cigarette smoking and menopausal hormone therapy

artículo científico publicado en 2012

Cross Cancer Genomic Investigation of Inflammation Pathway for Five Common Cancers: Lung, Ovary, Prostate, Breast, and Colorectal Cancer

artículo científico publicado en 2015

Cross-Cancer Genome-Wide Analysis of Lung, Ovary, Breast, Prostate, and Colorectal Cancer Reveals Novel Pleiotropic Associations

artículo científico publicado en 2016

Current smoking, occupation, N-acetyltransferase-2 and bladder cancer: a pooled analysis of genotype-based studies ⬇️

artículo científico publicado el 1 de diciembre de 2001

DNA Damage from Endogenous Processes, Workshop

artículo científico publicado en 1997

DNA Methylation Signatures Predicting Bevacizumab Efficacy in Metastatic Breast Cancer.

artículo científico publicado en 2018

DNA methylation changes measured in pre-diagnostic peripheral blood samples are associated with smoking and lung cancer risk

artículo científico publicado en 2016

Dietary glucosinolate intake, polymorphisms in selected biotransformation enzymes, and risk of prostate cancer

artículo científico publicado en 2010

EUELC project: a multi-centre, multipurpose study to investigate early stage NSCLC, and to establish a biobank for ongoing collaboration

artículo científico publicado en 2009

Early onset lung cancer, cigarette smoking and the SNP309 of the murine double minute-2 (MDM2) gene

artículo científico publicado en 2008

Effect of NAT1 and NAT2 genetic polymorphisms on colorectal cancer risk associated with exposure to tobacco smoke and meat consumption

artículo científico publicado en 2006

Elevated platelet count appears to be causally associated with increased risk of lung cancer: A Mendelian randomization analysis

scientific article published on 30 January 2019

Elevated risk of squamous-cell carcinoma of the lung in heavy smokers carrying the variant alleles of the TP53 Arg72Pro and p21 Ser31Arg polymorphisms

scientific article published on 23 October 2006

Empirical hierarchical bayes approach to gene-environment interactions: development and application to genome-wide association studies of lung cancer in TRICL.

artículo científico publicado en 2013

Epigenetic screen identifies genotype-specific promoter DNA methylation and oncogenic potential of CHRNB4

artículo científico publicado en 2012

Erratum to: Hierarchical modeling identifies novel lung cancer susceptibility variants in inflammation pathways among 10,140 cases and 11,012 controls

artículo científico publicado en 2016

Erratum: Corrigendum: A common coding variant in CASP8 is associated with breast cancer risk

scholarly article published in Nature Genetics

Erratum: Corrigendum: Rare variants of large effect in BRCA2 and CHEK2 affect risk of lung cancer

scholarly article published in Nature Genetics

Fine mapping of MHC region in lung cancer highlights independent susceptibility loci by ethnicity

artículo científico publicado en 2018

Functional variants in DCAF4 associated with lung cancer risk in European populations

artículo científico publicado en 2017

GPC5 rs2352028 variant and risk of lung cancer in never smokers

artículo científico publicado en 2010

Gene-set meta-analysis of lung cancer identifies pathway related to systemic lupus erythematosus

artículo científico publicado en 2017

Genes for human arylamine N-acetyltransferases in relation to loss of the short arm of chromosome 8 in bladder cancer

article

Genetic Polymorphisms in Genes Related to Oxidative Stress (GSTP1, GSTM1, GSTT1, CAT, MnSOD, MPO, eNOS) and Survival of Rectal Cancer Patients after Radiotherapy

artículo científico publicado en 2009

Genetic Risk Can Be Decreased: Quitting Smoking Decreases and Delays Lung Cancer for Smokers With High and Low CHRNA5 Risk Genotypes - A Meta-Analysis

artículo científico publicado en 2016

Genetic Variants in Epigenetic Pathways and Risks of Multiple Cancers in the GAME-ON Consortium

artículo científico publicado en 2017

Genetic determinants of telomere length and risk of common cancers: a Mendelian randomization study

artículo científico publicado en 2015

Genetic modifiers of radon-induced lung cancer risk: a genome-wide interaction study in former uranium miners

artículo científico publicado en 2018

Genetic polymorphisms in GST genes and survival of colorectal cancer patients treated with chemotherapy

artículo científico publicado en 2010

Genetic polymorphisms of MPO, GSTT1, GSTM1, GSTP1, EPHX1 and NQO1 as risk factors of early-onset lung cancer

artículo científico publicado en 2010

Genetic variants of PTPN2 are associated with lung cancer risk: a re-analysis of eight GWASs in the TRICL-ILCCO consortium

artículo científico publicado en 2017

Genome-wide interaction study of smoking behavior and non-small cell lung cancer risk in Caucasian population

artículo científico publicado en 2017

Genome-wide prediction of splice-modifying SNPs in human genes using a new analysis pipeline called AASsites

artículo científico publicado en 2011

Genotype relationships in the CYP3A locus in Caucasians

artículo científico publicado en 2004

Genotyping human polymorphic arylamine N-acetyltransferase: identification of new slow allotypic variants

artículo científico publicado en 1992

Glutathione-S-transferase M1, M3, T1 and P1 polymorphisms and susceptibility to non-small-cell lung cancer subtypes and hamartomas

artículo científico publicado en 2001

Hierarchical modeling identifies novel lung cancer susceptibility variants in inflammation pathways among 10,140 cases and 11,012 controls

artículo científico publicado en 2013

Hypomethylation of smoking-related genes is associated with future lung cancer in four prospective cohorts

artículo científico publicado en 2015

Identification of HERC5 and its potential role in NSCLC progression

artículo científico publicado en 2014

Identification of lung cancer histology-specific variants applying Bayesian framework variant prioritization approaches within the TRICL and ILCCO consortia

artículo científico publicado en 2015

Identification of shared and unique susceptibility pathways among cancers of the lung, breast, and prostate from genome-wide association studies and tissue-specific protein interactions

artículo científico publicado en 2015

Identification of susceptibility pathways for the role of chromosome 15q25.1 in modifying lung cancer risk

artículo científico publicado en 2018

Increased genetic vulnerability to smoking at CHRNA5 in early-onset smokers

artículo científico publicado en 2012

Influence of common genetic variation on lung cancer risk: meta-analysis of 14 900 cases and 29 485 controls

artículo científico publicado en 2012

Informed conditioning on clinical covariates increases power in case-control association studies

artículo científico publicado en 2012

Informed genome-wide association analysis with family history as a secondary phenotype identifies novel loci of lung cancer

artículo científico publicado en 2015

Inherited variation in circadian rhythm genes and risks of prostate cancer and three other cancer sites in combined cancer consortia

artículo científico

Insulin-like growth factor 1 pathway mutations and protein expression in resected non-small cell lung cancer

artículo científico publicado en 2014

International Lung Cancer Consortium: coordinated association study of 10 potential lung cancer susceptibility variants

artículo científico publicado en 2010

International Lung Cancer Consortium: pooled analysis of sequence variants in DNA repair and cell cycle pathways

artículo científico publicado en 2008

Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes

artículo científico publicado en 2017

Long noncoding RNA TARID directs demethylation and activation of the tumor suppressor TCF21 via GADD45A.

artículo científico publicado en 2014

Lung Cancer Risk in Never-Smokers of European Descent is Associated With Genetic Variation in the 5p15.33 TERT-CLPTM1Ll Region

artículo científico publicado en 2019

Lung cancer epigenetics and genetics

artículo científico publicado en 2008

META-GSA: Combining Findings from Gene-Set Analyses across Several Genome-Wide Association Studies

artículo científico publicado en 2015

Mapping AAC1 AAC2 and AACP, the genes for arylamine N-acetyltransferases, carcinogen metabolising enzymes on human chromosome 8p22, a region frequently deleted in tumours

article

Matrix metalloproteinase 1 (MMP1) is associated with early-onset lung cancer

artículo científico publicado en 2008

Meta- and pooled analysis of GSTP1 polymorphism and lung cancer: a HuGE-GSEC review

artículo científico publicado en 2009

Metabolic gene polymorphism frequencies in control populations

artículo científico publicado en 2001

Metabolic gene polymorphisms and lung cancer risk in non-smokers. An update of the GSEC study

artículo científico publicado en 2005

Methylome analysis and epigenetic changes associated with menarcheal age

artículo científico publicado en 2013

Modulation of DNA and protein adducts in smokers by genetic polymorphisms in GSTM1,GSTT1, NAT1 and NAT2.

artículo científico publicado en 2001

Myeloperoxidase (MPO) genotype and lung cancer histologic types: the MPO -463 A allele is associated with reduced risk for small cell lung cancer in smokers

artículo científico publicado en 2002

Novel Association of Genetic Markers Affecting CYP2A6 Activity and Lung Cancer Risk

artículo científico publicado en 2016

Novel genetic variants in the P38MAPK pathway gene ZAK and susceptibility to lung cancer

artículo científico publicado en 2017

Obesity, metabolic factors and risk of different histological types of lung cancer: A Mendelian randomization study

artículo científico publicado en 2017

Occupation, exposure to polycyclic aromatic hydrocarbons and laryngeal cancer risk

artículo científico publicado en 2005

Pathway-Based Kernel Boosting for the Analysis of Genome-Wide Association Studies

artículo científico

Pathway-analysis of published genome-wide association studies of lung cancer: A potential role for the CYP4F3 locus

artículo científico publicado en 2017

Pleiotropic Analysis of Lung Cancer and Blood Triglycerides

artículo científico publicado en 2016

Pleiotropic associations of risk variants identified for other cancers with lung cancer risk: the PAGE and TRICL consortia

artículo científico publicado en 2014

Polymorphisms in ABCG2, ABCC3 and CNT1 genes and their possible impact on chemotherapy outcome of lung cancer patients

artículo científico publicado en 2009

Polymorphisms in the Apoptotic Pathway Gene BCL-2 and Survival in Small Cell Lung Cancer

article

Polymorphisms in transporter and phase II metabolism genes as potential modifiers of the predisposition to and treatment outcome of de novo acute myeloid leukemia in Israeli ethnic groups

artículo científico

Polymorphisms of the centrosomal gene (FGFR1OP) and lung cancer risk: a meta-analysis of 14,463 cases and 44,188 controls

artículo científico publicado en 2016

Principles for the post-GWAS functional characterization of cancer risk loci

artículo científico publicado en 2011

Progressive lung cancer determined by expression profiling and transcriptional regulation

artículo científico publicado en 2012

Protein-altering germline mutations implicate novel genes related to lung cancer development

scientific article published on 11 May 2020

Publisher Correction: Shared heritability and functional enrichment across six solid cancers

scientific article published on 23 September 2019

Rapid screening assay for mutagen sensitivity and DNA repair capacity in human peripheral blood lymphocytes

artículo científico publicado en 2001

Rare variants of large effect in BRCA2 and CHEK2 affect risk of lung cancer

scientific journal article

Relevance of N-acetyltransferase 1 and 2 (NAT1, NAT2) genetic polymorphisms in non-small cell lung cancer susceptibility.

artículo científico publicado en 2001

Replication of lung cancer susceptibility loci at chromosomes 15q25, 5p15, and 6p21: a pooled analysis from the International Lung Cancer Consortium

artículo científico publicado en 2010

SULT1A1 genotype and susceptibility to colorectal cancer

artículo científico publicado en 2007

SULT1A1 genotype, active and passive smoking, and breast cancer risk by age 50 years in a German case-control study

artículo científico publicado en 2005

Shared heritability and functional enrichment across six solid cancers

artículo científico publicado en 2019

Shared heritability and functional enrichment across six solid cancers

Short telomeres in patients with vascular dementia: an indicator of low antioxidative capacity and a possible risk factor?

artículo científico publicado en 2000

Single nucleotide polymorphisms in matrix metalloproteinase genes and lung cancer chemotherapy response and prognosis

article

Slow N-acetylation genotype is a susceptibility factor in occupational and smoking related bladder cancer

artículo científico publicado en 1995

Specific combinations of DNA repair gene variants and increased risk for non-small cell lung cancer

artículo científico publicado en 2004

Susceptibility loci of CNOT6 in the general mRNA degradation pathway and lung cancer risk - a re-analysis of eight GWASs

artículo científico publicado en 2016

Synergistic cross-talk of hedgehog and interleukin-6 signaling drives growth of basal cell carcinoma

scientific article published on 01 October 2018

Telomere structure and maintenance gene variants and risk of five cancer types

artículo científico publicado en 2016

The CYP3A4*1B allele increases risk for small cell lung cancer: effect of gender and smoking dose

artículo científico publicado en 2003

The OncoArray Consortium: A Network for Understanding the Genetic Architecture of Common Cancers

artículo científico publicado en 2016

The double-edged sword of (re)expression of genes by hypomethylating agents: from viral mimicry to exploitation as priming agents for targeted immune checkpoint modulation

scientific article published on 31 March 2017

Xenogenetics in multifactorial disease susceptibility

artículo científico publicado en 1995

Lista de obras de Angela Risch

A Genome-wide Association Study of Lung Cancer Identifies a Region of Chromosome 5p15 Associated with Risk for Adenocarcinoma

A Novel Genetic Variant in Long Non-coding RNA Gene NEXN-AS1 is Associated with Risk of Lung Cancer

A common coding variant in CASP8 is associated with breast cancer risk

A comprehensive study of polymorphisms inABCB1, ABCC2andABCG2and lung cancer chemotherapy response and prognosis

A genome-wide association study of lung cancer identifies a region of chromosome 5p15 associated with risk for adenocarcinoma

A multiplex real-time PCR method for detection of GSTM1 and GSTT1 copy numbers

A network-based kernel machine test for the identification of risk pathways in genome-wide association studies

Arylarnine N-acetyltransferase as a potential biornarker in bladder cancer: fluorescent in situ hybridization and irnmunohistochernistry studies

Association analysis of driver-gene related genetic variants identified novel lung cancer susceptibility loci with 20,871 lung cancer cases and 15,971 controls

Association between Adult Height and Risk of Colorectal, Lung, and Prostate Cancer: Results from Meta-analyses of Prospective Studies and Mendelian Randomization Analyses

Association of metabolic gene polymorphisms with tobacco consumption in healthy controls

Associations between genetic variants in mRNA splicing-related genes and risk of lung cancer: a pathway-based analysis from published GWASs

CHRNA5 risk variant predicts delayed smoking cessation and earlier lung cancer diagnosis--a meta-analysis

CYP450 polymorphisms as risk factors for early-onset lung cancer: gender-specific differences

Cancer cell specific inhibition of Wnt/β-catenin signaling by forced intracellular acidification.

Comparison of multiple DNA adduct types in tumor adjacent human lung tissue: effect of cigarette smoking

Comparison of pathway analysis approaches using lung cancer GWAS data sets

Copy number variations of GSTT1 and GSTM1, colorectal cancer risk and possible effect modification of cigarette smoking and menopausal hormone therapy

Cross Cancer Genomic Investigation of Inflammation Pathway for Five Common Cancers: Lung, Ovary, Prostate, Breast, and Colorectal Cancer

Cross-Cancer Genome-Wide Analysis of Lung, Ovary, Breast, Prostate, and Colorectal Cancer Reveals Novel Pleiotropic Associations

Current smoking, occupation, N-acetyltransferase-2 and bladder cancer: a pooled analysis of genotype-based studies ⬇️

DNA Damage from Endogenous Processes, Workshop

DNA Methylation Signatures Predicting Bevacizumab Efficacy in Metastatic Breast Cancer.

DNA methylation changes measured in pre-diagnostic peripheral blood samples are associated with smoking and lung cancer risk

Dietary glucosinolate intake, polymorphisms in selected biotransformation enzymes, and risk of prostate cancer

EUELC project: a multi-centre, multipurpose study to investigate early stage NSCLC, and to establish a biobank for ongoing collaboration

Early onset lung cancer, cigarette smoking and the SNP309 of the murine double minute-2 (MDM2) gene

Effect of NAT1 and NAT2 genetic polymorphisms on colorectal cancer risk associated with exposure to tobacco smoke and meat consumption

Elevated platelet count appears to be causally associated with increased risk of lung cancer: A Mendelian randomization analysis

Elevated risk of squamous-cell carcinoma of the lung in heavy smokers carrying the variant alleles of the TP53 Arg72Pro and p21 Ser31Arg polymorphisms

Empirical hierarchical bayes approach to gene-environment interactions: development and application to genome-wide association studies of lung cancer in TRICL.

Epigenetic screen identifies genotype-specific promoter DNA methylation and oncogenic potential of CHRNB4

Erratum to: Hierarchical modeling identifies novel lung cancer susceptibility variants in inflammation pathways among 10,140 cases and 11,012 controls

Erratum: Corrigendum: A common coding variant in CASP8 is associated with breast cancer risk

Erratum: Corrigendum: Rare variants of large effect in BRCA2 and CHEK2 affect risk of lung cancer

Fine mapping of MHC region in lung cancer highlights independent susceptibility loci by ethnicity

Functional variants in DCAF4 associated with lung cancer risk in European populations

GPC5 rs2352028 variant and risk of lung cancer in never smokers

Gene-set meta-analysis of lung cancer identifies pathway related to systemic lupus erythematosus

Genes for human arylamine N-acetyltransferases in relation to loss of the short arm of chromosome 8 in bladder cancer

Genetic Polymorphisms in Genes Related to Oxidative Stress (GSTP1, GSTM1, GSTT1, CAT, MnSOD, MPO, eNOS) and Survival of Rectal Cancer Patients after Radiotherapy

Genetic Risk Can Be Decreased: Quitting Smoking Decreases and Delays Lung Cancer for Smokers With High and Low CHRNA5 Risk Genotypes - A Meta-Analysis

Genetic Variants in Epigenetic Pathways and Risks of Multiple Cancers in the GAME-ON Consortium

Genetic determinants of telomere length and risk of common cancers: a Mendelian randomization study

Genetic modifiers of radon-induced lung cancer risk: a genome-wide interaction study in former uranium miners

Genetic polymorphisms in GST genes and survival of colorectal cancer patients treated with chemotherapy

Genetic polymorphisms of MPO, GSTT1, GSTM1, GSTP1, EPHX1 and NQO1 as risk factors of early-onset lung cancer

Genetic variants of PTPN2 are associated with lung cancer risk: a re-analysis of eight GWASs in the TRICL-ILCCO consortium

Genome-wide interaction study of smoking behavior and non-small cell lung cancer risk in Caucasian population

Genome-wide prediction of splice-modifying SNPs in human genes using a new analysis pipeline called AASsites

Genotype relationships in the CYP3A locus in Caucasians

Genotyping human polymorphic arylamine N-acetyltransferase: identification of new slow allotypic variants

Glutathione-S-transferase M1, M3, T1 and P1 polymorphisms and susceptibility to non-small-cell lung cancer subtypes and hamartomas

Hierarchical modeling identifies novel lung cancer susceptibility variants in inflammation pathways among 10,140 cases and 11,012 controls

Hypomethylation of smoking-related genes is associated with future lung cancer in four prospective cohorts

Identification of HERC5 and its potential role in NSCLC progression

Identification of lung cancer histology-specific variants applying Bayesian framework variant prioritization approaches within the TRICL and ILCCO consortia

Identification of shared and unique susceptibility pathways among cancers of the lung, breast, and prostate from genome-wide association studies and tissue-specific protein interactions

Identification of susceptibility pathways for the role of chromosome 15q25.1 in modifying lung cancer risk

Increased genetic vulnerability to smoking at CHRNA5 in early-onset smokers

Influence of common genetic variation on lung cancer risk: meta-analysis of 14 900 cases and 29 485 controls

Informed conditioning on clinical covariates increases power in case-control association studies

Informed genome-wide association analysis with family history as a secondary phenotype identifies novel loci of lung cancer

Inherited variation in circadian rhythm genes and risks of prostate cancer and three other cancer sites in combined cancer consortia

Insulin-like growth factor 1 pathway mutations and protein expression in resected non-small cell lung cancer

International Lung Cancer Consortium: coordinated association study of 10 potential lung cancer susceptibility variants

International Lung Cancer Consortium: pooled analysis of sequence variants in DNA repair and cell cycle pathways

Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes

Long noncoding RNA TARID directs demethylation and activation of the tumor suppressor TCF21 via GADD45A.

Lung Cancer Risk in Never-Smokers of European Descent is Associated With Genetic Variation in the 5p15.33 TERT-CLPTM1Ll Region

Lung cancer epigenetics and genetics

META-GSA: Combining Findings from Gene-Set Analyses across Several Genome-Wide Association Studies

Mapping AAC1 AAC2 and AACP, the genes for arylamine N-acetyltransferases, carcinogen metabolising enzymes on human chromosome 8p22, a region frequently deleted in tumours

Matrix metalloproteinase 1 (MMP1) is associated with early-onset lung cancer

Meta- and pooled analysis of GSTP1 polymorphism and lung cancer: a HuGE-GSEC review

Metabolic gene polymorphism frequencies in control populations

Metabolic gene polymorphisms and lung cancer risk in non-smokers. An update of the GSEC study

Methylome analysis and epigenetic changes associated with menarcheal age

Modulation of DNA and protein adducts in smokers by genetic polymorphisms in GSTM1,GSTT1, NAT1 and NAT2.