Lista de obras - Mariangela Figini - Dominio Público Uruguay

(177)Lu- labeled MOv18 as compared to (131)I- or (90)Y-labeled MOv18 has the better therapeutic effect in eradication of alpha folate receptor-expressing tumor xenografts.

artículo científico publicado en 2009

90Y Labeling of monoclonal antibody MOv18 and preclinical validation for radioimmunotherapy of human ovarian carcinomas

artículo científico publicado en 2005

A novel isoform of pro-interleukin-18 expressed in ovarian tumors is resistant to caspase-1 and -4 processing

artículo científico publicado en 2004

A single-chain fragment against prostate specific membrane antigen as a tool to build theranostic reagents for prostate cancer.

artículo científico publicado en 2013

Activation of the osteopontin/matrix metalloproteinase-9 pathway correlates with prostate cancer progression.

artículo científico publicado en 2008

Anti-PSMA 124I-scFvD2B as a new immuno-PET tool for prostate cancer: preclinical proof of principle

scientific article published on 23 July 2019

Approaches to implement bispecific antibody treatment of ovarian carcinoma

artículo científico publicado en 1997

Broad-spectrum inhibition of HIV-1 by a monoclonal antibody directed against a gp120-induced epitope of CD4.

artículo científico publicado en 2011

CD27 costimulation augments the survival and antitumor activity of redirected human T cells in vivo

artículo científico publicado en 2011

CD95-mediated apoptosis is impaired at receptor level by cellular FLICE-inhibitory protein (long form) in wild-type p53 human ovarian carcinoma

artículo científico publicado en 2004

COVID-19 Vaccination in Health Care Workers in Italy: A Literature Review and a Report from a Comprehensive Cancer Center

artículo científico publicado en 2022

Characterization of a mouse-human chimeric antibody to a cancer-associated antigen

artículo científico publicado en 1992

Complement activated by chimeric anti-folate receptor antibodies is an efficient effector system to control ovarian carcinoma

artículo científico publicado en 2006

Computational design of novel peptidomimetic inhibitors of cadherin homophilic interactions

artículo científico publicado en 2015

Conversion of murine antibodies to human antibodies and their optimization for ovarian cancer therapy targeted to the folate receptor.

artículo científico publicado en 2008

Design, selection and optimization of an anti-TRAIL-R2/anti-CD3 bispecific antibody able to educate T cells to recognize and destroy cancer cells

artículo científico publicado en 2018

Development of 177Lu-scFvD2B as a Potential Immunotheranostic Agent for Tumors Overexpressing the Prostate Specific Membrane Antigen

artículo científico publicado en 2020

Effect of radiochemical modification on biodistribution of scFvD2B antibody fragment recognising prostate specific membrane antigen

artículo científico publicado en 2015

Glycolipids carrying Le(y) are preferentially expressed on small-cell lung cancer cells as detected by the monoclonal antibody MLuC1

artículo científico publicado el 8 de mayo de 1992

Harnessing engineered antibodies of the IgE class to combat malignancy: initial assessment of FcɛRI-mediated basophil activation by a tumour-specific IgE antibody to evaluate the risk of type I hypersensitivity.

artículo científico publicado en 2011

Highly efficient redirected anti-tumor activity of human lymphocytes transduced with a completely human chimeric immune receptor

artículo científico publicado en 2005

IgE Activates Monocytes from Cancer Patients to Acquire a Pro-Inflammatory Phenotype

scientific article published on 15 November 2020

In vivo imaging of prostate cancer using an anti-PSMA scFv fragment as a probe.

artículo científico publicado en 2016

In vivo persistence, tumor localization, and antitumor activity of CAR-engineered T cells is enhanced by costimulatory signaling through CD137 (4-1BB)

artículo científico publicado en 2011

PSMA-specific CAR-engineered T cells eradicate disseminated prostate cancer in preclinical models

artículo científico publicado en 2014

Protective versus pathogenic anti-CD4 immunity: insights from the study of natural resistance to HIV infection

artículo científico publicado en 2009

Redirected activity of human antitumor chimeric immune receptors is governed by antigen and receptor expression levels and affinity of interaction.

artículo científico publicado en 2007

Redirection of T-cell effector functions for cancer therapy: bispecific antibodies and chimeric antigen receptors

artículo científico

Reversion of transformed phenotype in ovarian cancer cells by intracellular expression of anti folate receptor antibodies.

artículo científico publicado en 2003

Rigorous optimization and validation of potent RNA CAR T cell therapy for the treatment of common epithelial cancers expressing folate receptor

artículo científico publicado en 2015

Shed HER2 extracellular domain in HER2-mediated tumor growth and in trastuzumab susceptibility

artículo científico publicado en 2010

Single-step purification of immunotoxins containing a high ionic charge ribosome inactivating protein clavin by carboxymethyl high-performance membrane chromatography

artículo científico publicado en 1999

Targeting FR-expressing cells in ovarian cancer with Fab-functionalized nanoparticles: a full study to provide the proof of principle from in vitro to in vivo.

artículo científico publicado en 2015

The use of a tropism-modified measles virus in folate receptor-targeted virotherapy of ovarian cancer

artículo científico publicado en 2006

Lista de obras de Mariangela Figini

(177)Lu- labeled MOv18 as compared to (131)I- or (90)Y-labeled MOv18 has the better therapeutic effect in eradication of alpha folate receptor-expressing tumor xenografts.

90Y Labeling of monoclonal antibody MOv18 and preclinical validation for radioimmunotherapy of human ovarian carcinomas

A novel isoform of pro-interleukin-18 expressed in ovarian tumors is resistant to caspase-1 and -4 processing

A single-chain fragment against prostate specific membrane antigen as a tool to build theranostic reagents for prostate cancer.

Activation of the osteopontin/matrix metalloproteinase-9 pathway correlates with prostate cancer progression.

Anti-PSMA 124I-scFvD2B as a new immuno-PET tool for prostate cancer: preclinical proof of principle

Approaches to implement bispecific antibody treatment of ovarian carcinoma

Broad-spectrum inhibition of HIV-1 by a monoclonal antibody directed against a gp120-induced epitope of CD4.

CD27 costimulation augments the survival and antitumor activity of redirected human T cells in vivo

CD95-mediated apoptosis is impaired at receptor level by cellular FLICE-inhibitory protein (long form) in wild-type p53 human ovarian carcinoma

COVID-19 Vaccination in Health Care Workers in Italy: A Literature Review and a Report from a Comprehensive Cancer Center

Characterization of a mouse-human chimeric antibody to a cancer-associated antigen

Complement activated by chimeric anti-folate receptor antibodies is an efficient effector system to control ovarian carcinoma

Computational design of novel peptidomimetic inhibitors of cadherin homophilic interactions

Conversion of murine antibodies to human antibodies and their optimization for ovarian cancer therapy targeted to the folate receptor.

Design, selection and optimization of an anti-TRAIL-R2/anti-CD3 bispecific antibody able to educate T cells to recognize and destroy cancer cells

Development of 177Lu-scFvD2B as a Potential Immunotheranostic Agent for Tumors Overexpressing the Prostate Specific Membrane Antigen

Effect of radiochemical modification on biodistribution of scFvD2B antibody fragment recognising prostate specific membrane antigen

Glycolipids carrying Le(y) are preferentially expressed on small-cell lung cancer cells as detected by the monoclonal antibody MLuC1

Harnessing engineered antibodies of the IgE class to combat malignancy: initial assessment of FcɛRI-mediated basophil activation by a tumour-specific IgE antibody to evaluate the risk of type I hypersensitivity.

Highly efficient redirected anti-tumor activity of human lymphocytes transduced with a completely human chimeric immune receptor

IgE Activates Monocytes from Cancer Patients to Acquire a Pro-Inflammatory Phenotype

In vivo imaging of prostate cancer using an anti-PSMA scFv fragment as a probe.

In vivo persistence, tumor localization, and antitumor activity of CAR-engineered T cells is enhanced by costimulatory signaling through CD137 (4-1BB)

PSMA-specific CAR-engineered T cells eradicate disseminated prostate cancer in preclinical models

Protective versus pathogenic anti-CD4 immunity: insights from the study of natural resistance to HIV infection

Redirected activity of human antitumor chimeric immune receptors is governed by antigen and receptor expression levels and affinity of interaction.

Redirection of T-cell effector functions for cancer therapy: bispecific antibodies and chimeric antigen receptors

Reversion of transformed phenotype in ovarian cancer cells by intracellular expression of anti folate receptor antibodies.

Rigorous optimization and validation of potent RNA CAR T cell therapy for the treatment of common epithelial cancers expressing folate receptor

Shed HER2 extracellular domain in HER2-mediated tumor growth and in trastuzumab susceptibility

Single-step purification of immunotoxins containing a high ionic charge ribosome inactivating protein clavin by carboxymethyl high-performance membrane chromatography

Targeting FR-expressing cells in ovarian cancer with Fab-functionalized nanoparticles: a full study to provide the proof of principle from in vitro to in vivo.

The use of a tropism-modified measles virus in folate receptor-targeted virotherapy of ovarian cancer