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Lista de obras de Hans K. Hasselbalch

A 7-Gene Signature Depicts the Biochemical Profile of Early Prefibrotic Myelofibrosis

artículo científico publicado en 2016

A der(18)t(9;18)(p13;p11) and a der(9;18)(p10;q10) in polycythemia vera associated with a hyperproliferative phenotype in transformation to postpolycythemic myelofibrosis.

artículo científico publicado en 2007

A distinct subtype of idiopathic myelofibrosis with bone marrow features mimicking hairy cell leukemia: evidence of an autoimmune pathogenesis

artículo científico publicado en 1987

A highly sensitive quantitative real-time PCR assay for determination of mutant JAK2 exon 12 allele burden

artículo científico publicado en 2012

A nationwide population-based cross-sectional survey of health-related quality of life in patients with myeloproliferative neoplasms in Denmark (MPNhealthSurvey): survey design and characteristics of respondents and nonrespondents

artículo científico publicado en 2017

A new era for IFN-α in the treatment of Philadelphia-negative chronic myeloproliferative neoplasms ⬇️

artículo científico publicado el 1 de diciembre de 2011

A new internet-based tool for reporting and analysing patient-reported outcomes and the feasibility of repeated data collection from patients with myeloproliferative neoplasms

artículo científico publicado en 2015

A novel immunohistochemical sequential multi-labelling and erasing technique enables epitope characterization of bone marrow pericytes in primary myelofibrosis

artículo científico publicado en 2012

A phase II study of vorinostat (MK-0683) in patients with polycythaemia vera and essential thrombocythaemia.

artículo científico publicado en 2013

A phase II study of vorinostat (MK-0683) in patients with primary myelofibrosis and post-polycythemia vera myelofibrosis

artículo científico publicado en 2014

A phase II trial of pegylated interferon alpha-2b therapy for polycythemia vera and essential thrombocythemia: feasibility, clinical and biologic effects, and impact on quality of life.

artículo científico publicado en 2006

A phase III randomized trial comparing glucocorticoid monotherapy versus glucocorticoid and rituximab in patients with autoimmune haemolytic anaemia.

artículo científico publicado en 2013

A possible role for STI571 in the treatment of idiopathic myelofibrosis

artículo científico publicado en 2001

A remarkable hematological and molecular response pattern in a patient with polycythemia vera during combination therapy with simvastatin and alendronate

artículo científico publicado en 2016

A retrospective analysis of the impact of treatments and blood counts on survival and the risk of vascular events during the course of polycythaemia vera.

artículo científico publicado en 2017

A role of NF-E2 in chronic inflammation and clonal evolution in essential thrombocythemia, polycythemia vera and myelofibrosis?

artículo científico publicado en 2013

A unified definition of clinical resistance and intolerance to hydroxycarbamide in polycythaemia vera and primary myelofibrosis: results of a European LeukemiaNet (ELN) consensus process

artículo científico publicado en 2009

A unified definition of clinical resistance/intolerance to hydroxyurea in essential thrombocythemia: results of a consensus process by an international working group.

artículo científico publicado en 2006

Aberrations of chromosome 6 in 193 newly diagnosed untreated cases of chronic lymphocytic leukemia

scientific article published on 01 May 1991

Activated platelets enhance IL-10 secretion and reduce TNF-α secretion by monocytes

artículo científico publicado en 2013

Acute leukemia and myelodysplasia in patients with a Philadelphia chromosome negative chronic myeloproliferative disorder treated with hydroxyurea alone or with hydroxyurea after busulphan

artículo científico publicado en 2003

Age-Related Macular Degeneration in Patients With Chronic Myeloproliferative Neoplasms

artículo científico publicado en 2017

Alcohol intolerance in the hypereosinophilic syndrome

scientific article published on 01 February 1988

Anagrelide treatment in 52 patients with chronic myeloproliferative diseases

artículo científico publicado en 2004

Anemia is present years before myelodysplastic syndrome diagnosis: Results from the pre-diagnostic period.

artículo científico publicado en 2017

Angiogenesis in pulmonary hypertension with myelofibrosis

scientific article published on 06 May 2008

Antecedent cardiovascular disease and autoimmunity in Philadelphia-negative chronic myeloproliferative neoplasms.

artículo científico publicado en 2015

Association of the blood eosinophil count with hematological malignancies and mortality

artículo científico publicado en 2015

B lymphocyte depletion with the monoclonal antibody rituximab in Graves' disease: a controlled pilot study

artículo científico publicado en 2007

B-cell depletion with rituximab in the treatment of autoimmune diseases. Graves' ophthalmopathy the latest addition to an expanding family

artículo científico publicado en 2007

B-cell depletion with rituximab-a targeted therapy for Graves' disease and autoimmune thyroiditis

artículo científico publicado en 2003

B-cell frequencies and immunoregulatory phenotypes in myeloproliferative neoplasms: Influence of ruxolitinib, interferon-α2, or combination treatment

scientific article published on 18 August 2019

Bone marrow histomorphology and JAK2 mutation status in essential thrombocythemia

artículo científico publicado en 2007

Characterization of blood donors with high haemoglobin concentration

artículo científico publicado en 2012

Chronic inflammation and autoimmunity as risk factors for the development of chronic myelomonocytic leukemia?

artículo científico publicado en 2016

Chronic inflammation as a promotor of mutagenesis in essential thrombocythemia, polycythemia vera and myelofibrosis. A human inflammation model for cancer development?

artículo científico publicado en 2012

Chronic kidney disease in patients with the Philadelphia-negative chronic myeloproliferative neoplasms

artículo científico publicado en 2014

Chronic myeloproliferative neoplasms and subsequent cancer risk: a Danish population-based cohort study

artículo científico publicado en 2011

Circulating YKL-40 in myelofibrosis a potential novel biomarker of disease activity and the inflammatory state

artículo científico publicado en 2014

Circulating YKL-40 in patients with essential thrombocythemia and polycythemia vera treated with the novel histone deacetylase inhibitor vorinostat

artículo científico publicado en 2014

Circulating hyaluronan in the myelofibrosis/osteomyelosclerosis syndrome and other myeloproliferative disorders

artículo científico publicado en 1991

Collagen metabolism and enzymes of the urokinase plasminogen activator system in chronic myeloproliferative disorders: correlation between plasma-soluble urokinase plasminogen activator receptor and serum markers for collagen metabolism.

artículo científico publicado en 2003

Combination therapy with interferon and JAK1-2 inhibitor is feasible: Proof of concept with rapid reduction in JAK2V617F-allele burden in polycythemia vera

artículo científico publicado en 2014

Corrigendum to "Combination therapy with interferon and JAK1-2 inhibitor is feasible. Proof of concept with rapid reduction in JAK2V617F-allele burden in Polycythemia Vera" [Leuk. Res. Rep. 3 (2) (2014) 73-75].

artículo científico publicado en 2015

Data-driven analysis of JAK2V617F kinetics during interferon-alpha2 treatment of patients with polycythemia vera and related neoplasms

artículo científico publicado en 2020

Demonstrated Benefit of Continuous Interferon-Alpha-2b Therapy in Hairy Cell Leukemia. A Two-Year Follow-Up

artículo científico publicado en 1991

Diagnosis, pathogenesis and treatment of the myeloproliferative disorders essential thrombocythemia, polycythemia vera and essential megakaryocytic granulocytic metaplasia and myelofibrosis.

artículo científico publicado en 1999

Differential Dynamics of CALR Mutant Allele Burden in Myeloproliferative Neoplasms during Interferon Alfa Treatment

artículo científico publicado en 2016

Discordance between the cortisol response to insulin-hypoglycemia and 30-minute ACTH stimulation test in chronic alcoholic men.

artículo científico publicado en 1987

Does primary myelofibrosis involve a defective stem cell niche? From concept to evidence.

artículo científico publicado en 2008

Effect of thrombopoietin-receptor agonists on circulating cytokine and chemokine levels in patients with primary immune thrombocytopenia (ITP).

artículo científico publicado en 2016

Elevated plasma levels of TIMP-1 correlate with plasma suPAR/uPA in patients with chronic myeloproliferative disorders

artículo científico publicado en 2003

Elevated soluble urokinase plasminogen activator receptor in plasma from patients with idiopathic myelofibrosis or polycythaemia vera

artículo científico publicado en 2002

Eosinophilia in routine blood samples and the subsequent risk of hematological malignancies and death

artículo científico publicado en 2013

Eosinophilia in routine blood samples as a biomarker for solid tumor development - A study based on the Copenhagen Primary Care Differential Count (CopDiff) Database.

artículo científico publicado en 2014

Epigenetic changes in myelofibrosis: Distinct methylation changes in the myeloid compartments and in cases with ASXL1 mutations

artículo científico publicado en 2017

Expansion of circulating CD56bright natural killer cells in patients with JAK2-positive chronic myeloproliferative neoplasms during treatment with interferon-α.

artículo científico publicado en 2014

Extreme neutrophil granulocytosis in a patient with anaplastic large cell lymphoma of T-cell lineage.

artículo científico publicado en 2007

FLT3-mediated p38-MAPK activation participates in the control of megakaryopoiesis in primary myelofibrosis.

artículo científico publicado en 2011

Fibroproliferative activity in patients with immune thrombocytopenia (ITP) treated with thrombopoietic agents

artículo científico publicado en 2011

Frequent occurrence of anticardiolipin antibodies, Factor V Leiden mutation, and perturbed endothelial function in chronic myeloproliferative disorders

artículo científico publicado en 2002

High expression of carcinoembryonic antigen-related cell adhesion molecule (CEACAM) 6 and 8 in primary myelofibrosis

artículo científico publicado en 2011

High prevalence of arterial thrombosis in JAK2 mutated essential thrombocythaemia: independence of the V617F allele burden

artículo científico publicado en 2008

High rate of abnormal blood values and vascular complications before diagnosis of myeloproliferative neoplasms.

artículo científico publicado en 2015

Hydroxycarbamide: a user's guide for chronic myeloproliferative disorders.

artículo científico publicado en 2011

Hypercalcemia in idiopathic myelofibrosis: modulation of calcium and collagen homeostasis by 1,25-dihydroxyvitamin D3

artículo científico publicado en 1992

Hypothalamic-pituitary and thyroid function in chronic alcoholics with neurological complications

artículo científico publicado en 1990

Hypothesis: a possible role for interferon in the treatment of idiopathic myelofibrosis

artículo científico publicado en 1988

Idiopathic myelofibrosis--an update with particular reference to clinical aspects and prognosis

artículo científico publicado en 1993

Imatinib mesylate in idiopathic and postpolycythemic myelofibrosis

artículo científico publicado en 2003

Incidence, clinical features and outcome of essential thrombocythaemia in a well defined geographical area

artículo científico publicado en 2000

Increase in circulating CD4+CD25+Foxp3+ T cells in patients with Philadelphia-negative chronic myeloproliferative neoplasms during treatment with IFN-

artículo científico publicado en 2011

Increased circulating platelet-leukocyte aggregates in myeloproliferative disorders is correlated to previous thrombosis, platelet activation and platelet count

artículo científico publicado en 2001

Increased gene expression of histone deacetylases in patients with Philadelphia-negative chronic myeloproliferative neoplasms

artículo científico publicado en 2011

Increased iron stores prolong the QT interval - a general population study including 20 261 individuals and meta-analysis of thalassaemia major.

artículo científico publicado en 2016

Increased platelet activation and abnormal membrane glycoprotein content and redistribution in myeloproliferative disorders

artículo científico publicado en 2000

Interferon alfa in the treatment of Philadelphia-negative chronic myeloproliferative neoplasms

scientific article published on 16 May 2011

Interferon and the treatment of polycythemia vera, essential thrombocythemia and myelofibrosis

artículo científico publicado en 2013

Interferon in myelofibrosis

artículo científico publicado en 1988

Interferon in polycythemia vera and related neoplasms. Can it become the treatment of choice without a randomized trial?

artículo científico publicado en 2015

Interferon-α induces marked alterations in circulating regulatory T cells, NK cell subsets, and dendritic cells in patients with JAK2V617F-positive essential thrombocythemia and polycythemia vera.

artículo científico publicado en 2015

Is thrombocytosis a valid indicator of advanced stage and high mortality of gynecological cancer?

artículo científico publicado en 2015

Lack of somatic mutations in the catalytic domains of CREBBP and EP300 genes implies a role for histone deacetylase inhibition in myeloproliferative neoplasms

artículo científico publicado en 2011

Limited efficacy of hydroxyurea in lowering of the JAK2 V617F allele burden

artículo científico publicado en 2009

Long term molecular responses in a cohort of Danish patients with essential thrombocythemia, polycythemia vera and myelofibrosis treated with recombinant interferon alpha

artículo científico publicado en 2013

MPL mutations in myeloproliferative disorders: analysis of the PT-1 cohort.

artículo científico publicado en 2008

MPNs as Inflammatory Diseases: The Evidence, Consequences, and Perspectives

artículo científico publicado en 2015

Mathematical modelling as a proof of concept for MPNs as a human inflammation model for cancer development

artículo científico publicado en 2017

Mediators of Inflammation in Myeloproliferative Neoplasms: State of the Art.

artículo científico publicado en 2015

Minimal residual disease after long-term interferon-alpha2 treatment: a report on hematological, molecular and histomorphological response patterns in 10 patients with essential thrombocythemia and polycythemia vera

artículo científico publicado en 2015

Minimal residual disease and normalization of the bone marrow after long-term treatment with alpha-interferon2b in polycythemia vera. A report on molecular response patterns in seven patients in sustained complete hematological remission

article

Minimal residual disease or cure in MPNs? Rationales and perspectives on combination therapy with interferon-alpha2 and ruxolitinib.

artículo científico publicado en 2017

Molecular mechanisms associated with leukemic transformation of MPL-mutant myeloproliferative neoplasms

artículo científico publicado en 2010

Molecular profiling as a novel tool to predict response to interferon-α2 in MPNs: The proof of concept in early myelofibrosis

artículo científico publicado en 2017

Molecular profiling of peripheral blood cells from patients with polycythemia vera and related neoplasms: identification of deregulated genes of significance for inflammation and immune surveillance

artículo científico publicado en 2012

Myeloproliferative blood cancers as a human neuroinflammation model for development of Alzheimer's disease: evidences and perspectives

scientific article published on 23 August 2020

Myeloproliferative neoplasms and inflammation: whether to target the malignant clone or the inflammatory process or both

artículo científico publicado en 2016

Myeloproliferative neoplasms in five multiple sclerosis patients

artículo científico publicado en 2013

Neo-antigen specific memory T-cell responses in healthy individuals

artículo científico publicado en 2019

Non-invasive imaging of retinal blood flow in myeloproliferative neoplasms

artículo científico publicado en 2016

On the pathogenesis of angiogenesis in idiopathic myelofibrosis

artículo científico publicado en 1990

Optimal therapy for polycythemia vera and essential thrombocythemia: Preferred use of interferon therapy based on phase 2 trials

artículo científico publicado en 2016

Perspectives on chronic inflammation in essential thrombocythemia, polycythemia vera, and myelofibrosis: is chronic inflammation a trigger and driver of clonal evolution and development of accelerated atherosclerosis and second cancer?

artículo científico publicado en 2012

Perspectives on interferon-alpha in the treatment of Polycythemia vera and related Myeloproliferative neoplasms: minimal residual disease and cure?

artículo científico publicado en 2019

Perspectives on the impact of JAK-inhibitor therapy upon inflammation-mediated comorbidities in myelofibrosis and related neoplasms.

artículo científico

Perspectives on the increased risk of second cancer in patients with essential thrombocythemia, polycythemia vera and myelofibrosis.

artículo científico publicado en 2015

Philadelphia-negative classical myeloproliferative neoplasms: critical concepts and management recommendations from European LeukemiaNet.

artículo científico publicado en 2011

Prevalence and clinical significance of neutropenia discovered in routine complete blood cell counts: a longitudinal study

artículo científico publicado en 2016

Prevalence and phenotypes of JAK2 V617F and calreticulin mutations in a Danish general population

scientific article published on 19 June 2019

Quantitative assessment of the JAK2 V617F allele burden: equivalent levels in peripheral blood and bone marrow

scientific article published on 12 July 2007

Response criteria for essential thrombocythemia and polycythemia vera: result of a European LeukemiaNet consensus conference.

scientific article published on 10 March 2009

Response criteria for myelofibrosis with myeloid metaplasia: results of an initiative of the European Myelofibrosis Network (EUMNET).

artículo científico publicado en 2005

Risk of lymphoma and solid cancer among patients with rheumatoid arthritis in a primary care setting

artículo científico publicado en 2014

Rituximab and dexamethasone vs dexamethasone monotherapy in newly diagnosed patients with primary immune thrombocytopenia

artículo científico publicado en 2013

Rituximab chimeric anti-CD20 monoclonal antibody treatment for adult refractory idiopathic thrombocytopenic purpura

artículo científico publicado en 2005

Ruxolitinib is manageable in patients with myelofibrosis and severe thrombocytopenia: a report on 12 Danish patients.

artículo científico publicado en 2015

SU6668 in idiopathic myelofibrosis--a rational therapeutic approach targeting several tyrosine kinases of importance for the myeloproliferation and the development of bone marrow fibrosis and angiogenesis

artículo científico publicado en 2003

Safety and efficacy of combination therapy of interferon-α2 and ruxolitinib in polycythemia vera and myelofibrosis

artículo científico publicado en 2018

Second malignancies in hydroxyurea and interferon-treated Philadelphia-negative myeloproliferative neoplasms

artículo científico publicado en 2016

Serum hyaluronan is increased in malignant lymphoma.

artículo científico publicado en 1995

Serum laminin P1 in idiopathic myelofibrosis and related diseases

scientific article published on 01 August 1994

Serum markers for type IV collagen and type III procollagen in the myelofibrosis-osteomyelosclerosis syndrome and other chronic myeloproliferative disorders

artículo científico publicado en 1986

Smoking and philadelphia-negative chronic myeloproliferative neoplasms

artículo científico publicado en 2015

Smoking as a contributing factor for development of polycythemia vera and related neoplasms

artículo científico

Smoking is associated with increased risk of myeloproliferative neoplasms: A general population-based cohort study

artículo científico publicado en 2018

Smoking, blood cells and myeloproliferative neoplasms: meta-analysis and Mendelian randomization of 2·3 million people

artículo científico publicado en 2019

Sorted peripheral blood cells identify CALR mutations in B- and T-lymphocytes

artículo científico publicado en 2017

Spontaneous T-cell responses against Arginase-1 in the chronic myeloproliferative neoplasms relative to disease stage and type of driver mutation

artículo científico publicado en 2018

Statins in the treatment of polycythaemia vera and allied disorders: an antithrombotic and cytoreductive potential?

artículo científico publicado en 2006

Successful treatment of anemia in idiopathic myelofibrosis with recombinant human erythropoietin

artículo científico publicado en 2002

Survival after a blood alcohol of 1127 mg/dl

scientific article published on 01 August 1981

Survival of patients with chronic myeloproliferative neoplasms and new primary cancers: a population-based cohort study

artículo científico

Sustained major molecular response on interferon alpha-2b in two patients with polycythemia vera.

artículo científico publicado en 2008

Sustained remission of platelet counts following monoclonal anti-CD20 antibody therapy in two cases of idiopathic autoimmune thrombocytopenia and neutropenia.

artículo científico publicado en 2001

The CALR exon 9 mutations are shared neoantigens in patients with CALR mutant chronic myeloproliferative neoplasms

artículo científico publicado en 2016

The Copenhagen Primary Care Differential Count (CopDiff) database

artículo científico publicado en 2014

The Danish National Chronic Myeloid Neoplasia Registry

artículo científico publicado en 2016

The JAK2 V617F allele burden in essential thrombocythemia, polycythemia vera and primary myelofibrosis--impact on disease phenotype

artículo científico publicado en 2007

The JAK2 V617F mutation involves B- and T-lymphocyte lineages in a subgroup of patients with Philadelphia-chromosome negative chronic myeloproliferative disorders

scientific article published on 01 March 2007

The JAK2V617F allele burden and STAT3- and STAT5 phosphorylation in myeloproliferative neoplasms: early prefibrotic myelofibrosis compared with essential thrombocythemia, polycythemia vera and myelofibrosis

artículo científico publicado en 2011

The Role of Reactive Oxygen Species in Myelofibrosis and Related Neoplasms

artículo científico publicado en 2015

The V617F and exon 9 mutations are shared immunogenic neoantigens in hematological malignancy

scientific article published on 02 August 2017

The impact of interferon-alpha2 on HLA genes in patients with polycythemia vera and related neoplasms

artículo científico publicado en 2016

The platelet-cancer loop in myeloproliferative cancer. Is thrombocythemia an enhancer of cancer invasiveness and metastasis in essential thrombocythemia, polycythemia vera and myelofibrosis?

artículo científico publicado en 2014

The rationale for B lymphocyte depletion in Graves' disease. Monoclonal anti-CD20 antibody therapy as a novel treatment option.

artículo científico publicado en 2006

The red blood cell count and the erythrocyte sedimentation rate in the diagnosis of polycythaemia vera

artículo científico publicado en 2019

The role of cytokines in the initiation and progression of myelofibrosis.

artículo científico

Thrombopoietin-receptor agonists in haematological disorders: The Danish experience ⬇️

artículo científico publicado el 20 de diciembre de 2011

Transcriptional profiling of whole blood identifies a unique 5-gene signature for myelofibrosis and imminent myelofibrosis transformation

artículo científico publicado en 2014

Treatment-resistant severe, active Graves' ophthalmopathy successfully treated with B lymphocyte depletion

artículo científico publicado en 2006

Urinary free cortisol during pregnancy

scientific article published on 01 January 1984

V617F mutation in JAK2 is associated with poorer survival in idiopathic myelofibrosis

artículo científico publicado en 2005

WHO classification 2008 of myeloproliferative neoplasms: a workshop learning effect--the Danish experience

artículo científico publicado en 2015

Whole blood assay for NK activity in splenectomized and non-splenectomized hairy cell leukemia patients during IFN-α-2b treatment

artículo científico publicado en 1989

Whole blood transcriptional profiling reveals deregulation of oxidative and antioxidative defence genes in myelofibrosis and related neoplasms. Potential implications of downregulation of Nrf2 for genomic instability and disease progression

artículo científico publicado en 2014

Whole blood transcriptional profiling reveals significant down-regulation of human leukocyte antigen class I and II genes in essential thrombocythemia, polycythemia vera and myelofibrosis

scientific article published on 15 May 2013

Whole-blood transcriptional profiling of interferon-inducible genes identifies highly upregulated IFI27 in primary myelofibrosis

artículo científico publicado en 2011

Whole-exome sequencing and genome-wide methylation analyses identify novel disease associated mutations and methylation patterns in idiopathic hypereosinophilic syndrome

artículo científico publicado en 2015

World Health Organization-defined classification of myeloproliferative neoplasms: morphological reproducibility and clinical correlations--the Danish experience

artículo científico publicado en 2013

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