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Lista de obras de Paul G. Thomas

A Cell for the Ages: Human γδ T Cells across the Lifespan

scientific article published on 24 November 2020

A Cysteine Zipper Stabilizes a Pre-Fusion F Glycoprotein Vaccine for Respiratory Syncytial Virus

artículo científico publicado en 2015

A Modular Cytokine Analysis Method Reveals Novel Associations With Clinical Phenotypes and Identifies Sets of Co-signaling Cytokines Across Influenza Natural Infection Cohorts and Healthy Controls

scientific article published on 18 June 2019

A comprehensive collection of systems biology data characterizing the host response to viral infection.

artículo científico publicado en 2014

A constant companion: immune recognition and response to cytomegalovirus with aging and implications for immune fitness.

artículo científico publicado en 2017

A multi-valent vaccine approach that elicits broad immunity within an influenza subtype.

artículo científico publicado en 2009

An Epithelial Integrin Regulates the Amplitude of Protective Lung Interferon Responses against Multiple Respiratory Pathogens

artículo científico publicado en 2016

An unexpected antibody response to an engineered influenza virus modifies CD8+ T cell responses

artículo científico publicado en 2006

Apoptosis-Inducing-Factor-Dependent Mitochondrial Function Is Required for T Cell but Not B Cell Function.

artículo científico publicado en 2016

Astrovirus infects actively secreting goblet cells and alters the gut mucus barrier

scientific article published on 29 April 2020

Bach2 Negatively Regulates T Follicular Helper Cell Differentiation and Is Critical for CD4+ T Cell Memory

artículo científico publicado en 2019

Balancing Immune Protection and Immune Pathology by CD8(+) T-Cell Responses to Influenza Infection

artículo científico publicado en 2016

Bohemian T cell receptors: sketching the repertoires of unconventional lymphocytes

artículo científico publicado en 2018

Cell-Intrinsic Barriers of T Cell-Based Immunotherapy

artículo científico publicado en 2016

Cell-mediated protection in influenza infection.

artículo científico publicado en 2006

Characterization of innate responses to influenza virus infection in a novel lung type I epithelial cell model

artículo científico publicado en 2013

Characterizing Emerging Canine H3 Influenza Viruses

artículo científico publicado en 2020

Chromatin condensation via the condensin II complex is required for peripheral T-cell quiescence

artículo científico publicado el 17 de diciembre de 2010

Chronic helminth infections impair pneumococcal vaccine responses

artículo científico publicado en 2014

Clonally diverse CD38+HLA-DR+CD8+ T cells persist during fatal H7N9 disease.

artículo científico publicado en 2018

Clonally related CD8+ T cells responsible for rapid population of both diffuse nasal-associated lymphoid tissue and lung after respiratory virus infection

artículo científico publicado en 2011

Compromised respiratory function in lethal influenza infection is characterized by the depletion of type I alveolar epithelial cells beyond threshold levels

artículo científico publicado en 2013

Consequences of immunodominant epitope deletion for minor influenza virus-specific CD8+-T-cell responses

artículo científico publicado en 2005

Constrained evolution drives limited influenza diversity

artículo científico publicado en 2012

Contemporary seasonal influenza A (H1N1) virus infection primes for a more robust response to split inactivated pandemic influenza A (H1N1) Virus vaccination in ferrets

artículo científico publicado en 2010

Crystal structure, conformational fixation and entry-related interactions of mature ligand-free HIV-1 Env

artículo científico publicado en 2015

Cytokine Profiles of Severe Influenza Virus-Related Complications in Children

artículo científico publicado en 2017

Cytomegalovirus infection enhances the immune response to influenza.

artículo científico publicado en 2015

DAI Senses Influenza A Virus Genomic RNA and Activates RIPK3-Dependent Cell Death

artículo científico publicado en 2016

Dangerous for ferrets: lethal for humans?

artículo científico publicado el 20 de febrero de 2012

Data from CAR T-cell Design-dependent Remodeling of the Brain Tumor Immune Microenvironment Modulates Tumor-associated Macrophages and Anti-glioma Activity

De Novo Epigenetic Programs Inhibit PD-1 Blockade-Mediated T Cell Rejuvenation

artículo científico publicado en 2017

Defining antigen-specific plasmablast and memory B cell subsets in human blood after viral infection or vaccination

artículo científico publicado en 2016

Defining the risk of SARS-CoV-2 variants on immune protection

artículo científico publicado en 2022

Dendritic cells activated by an anti-inflammatory agent induce CD4(+) T helper type 2 responses without impairing CD8(+) memory and effector cytotoxic T-lymphocyte responses

artículo científico publicado en 2009

Depletion of Alveolar Macrophages during Influenza Infection Facilitates Bacterial Superinfections

artículo científico publicado el 26 de junio de 2013

Detection of antibodies against Turkey astrovirus in humans

artículo científico publicado en 2014

Development of dual PLD1/2 and PLD2 selective inhibitors from a common 1,3,8-Triazaspiro[4.5]decane Core: discovery of Ml298 and Ml299 that decrease invasive migration in U87-MG glioblastoma cells.

artículo científico publicado en 2013

Differential host response, rather than early viral replication efficiency, correlates with pathogenicity caused by influenza viruses

artículo científico publicado en 2013

Distinct Epigenetic Signatures Delineate Transcriptional Programs during Virus-Specific CD8+ T Cell Differentiation

artículo científico publicado en 2014

Distinct epigenetic signatures delineate transcriptional programs during virus-specific CD8(+) T cell differentiation

artículo científico publicado en 2014

Distinct inflammatory profiles distinguish COVID-19 from influenza with limited contributions from cytokine storm

artículo científico publicado en 2020

Diverse heterologous primary infections radically alter immunodominance hierarchies and clinical outcomes following H7N9 influenza challenge in mice

artículo científico publicado en 2015

Ecological analysis of antigen-specific CTL repertoires defines the relationship between naïve and immune T-cell populations

artículo científico publicado el 14 de enero de 2013

Enhanced Susceptibility of Ago1/3 Double-Null Mice to Influenza A Virus Infection.

artículo científico publicado en 2012

Enhanced susceptibility of Ago1/3 double-null mice to influenza A virus infection.

artículo científico publicado en 2012

Eosinophils Promote Antiviral Immunity in Mice Infected with Influenza A Virus

artículo científico publicado en 2017

Epitope-specific TCR  repertoire diversity imparts no functional advantage on the CD8+ T cell response to cognate viral peptides

artículo científico publicado en 2008

Establishment of memory CD8+ T cells with live attenuated influenza virus across different vaccination doses

artículo científico publicado en 2016

Evaluation of IFITM3 rs12252 Association With Severe Pediatric Influenza Infection

artículo científico publicado en 2017

Exogenous remodeling of lung resident macrophages protects against infectious consequences of bone marrow-suppressive chemotherapy

artículo científico publicado en 2016

Exuberant fibroblast activity compromises lung function via ADAMTS4

artículo científico publicado en 2020

Functional implications of T cell receptor diversity

artículo científico publicado en 2009

Gamma delta T cell reconstitution is associated with fewer infections and improved event-free survival after hematopoietic stem cell transplantation for pediatric leukemia.

artículo científico publicado en 2014

HVEM Imprints Memory Potential on Effector CD8 T Cells Required for Protective Mucosal Immunity

artículo científico publicado en 2017

Heightened self-reactivity associated with selective survival, but not expansion, of naïve virus-specific CD8+ T cells in aged mice

artículo científico publicado en 2016

Helminth infections predispose mice to pneumococcal pneumonia but not to other pneumonic pathogens

artículo científico publicado en 2014

Hidden epitopes emerge in secondary influenza virus-specific CD8+ T cell responses

artículo científico publicado en 2007

Highly pathological influenza A virus infection is associated with augmented expression of PD-1 by functionally compromised virus-specific CD8+ T cells

artículo científico publicado en 2013

Hitting the Target: How T Cells Detect and Eliminate Tumors

artículo científico publicado en 2018

Host detection and the stealthy phenotype in influenza virus infection.

artículo científico publicado en 2015

Human CD8+ T cell cross-reactivity across influenza A, B and C viruses

scientific article published on 18 February 2019

Human H7N9 and H5N1 influenza viruses differ in induction of cytokines and tissue tropism.

artículo científico publicado en 2014

Human Mucosal-Associated Invariant T Cells in Older Individuals Display Expanded TCRαβ Clonotypes with Potent Antimicrobial Responses

scientific article published on 27 January 2020

Identifying T Cell Receptors from High-Throughput Sequencing: Dealing with Promiscuity in TCRα and TCRβ Pairing

artículo científico publicado en 2017

Immune biasing by helminth glycans.

artículo científico publicado en 2004

Immunity to avian influenza A viruses.

artículo científico publicado en 2009

Immunity to influenza. Preventing infection and regulating disease

artículo científico publicado en 2015

Immunity to seasonal and pandemic influenza A viruses

artículo científico publicado en 2011

Implementing hospital-based surveillance for severe acute respiratory infections caused by influenza and other respiratory pathogens in New Zealand

artículo científico publicado en 2014

Influenza and the challenge for immunology

artículo científico publicado en 2006

Influenza epitope-specific CD8+ T cell avidity, but not cytokine polyfunctionality, can be determined by TCRβ clonotype

artículo científico publicado en 2010

Influenza-specific lung-resident memory T cells are proliferative and polyfunctional and maintain diverse TCR profiles.

artículo científico publicado en 2018

Interrogating the relationship between naïve and immune antiviral T cell repertoires

artículo científico publicado en 2013

Intranasal influenza infection of mice and methods to evaluate progression and outcome

artículo científico publicado en 2013

Intratumoral injection of the seasonal flu shot converts immunologically cold tumors to hot and serves as an immunotherapy for cancer

artículo científico publicado en 2019

Iterative structure-based improvement of a fusion-glycoprotein vaccine against RSV.

scientific article published on August 2016

Lipid composition of viral envelope of three strains of influenza virus - not all viruses are created equal.

artículo científico publicado en 2015

Lipidomic profiling of influenza infection identifies mediators that induce and resolve inflammation

scientific article published on July 2013

Low-dose in vivo protection and neutralization across SARS-CoV-2 variants by monoclonal antibody combinations

artículo científico publicado en 2021

MR1-restricted mucosal-associated invariant T (MAIT) cells respond to mycobacterial vaccination and infection in nonhuman primates

artículo científico publicado en 2016

Maintenance of the EBV-specific CD8+ TCRαβ repertoire in immunosuppressed lung transplant recipients

artículo científico publicado en 2016

Maturation of dendritic cell 2 phenotype by a helminth glycan uses a Toll-like receptor 4-dependent mechanism

artículo científico publicado en 2003

Membrane association of the CD3ε signaling domain is required for optimal T cell development and function.

artículo científico publicado en 2014

Metabolic signaling directs the reciprocal lineage decisions of αβ and γδ T cells

artículo científico publicado en 2018

Molecular basis for universal HLA-A*0201-restricted CD8+ T-cell immunity against influenza viruses

artículo científico publicado en 2016

Molecular-level analysis of the serum antibody repertoire in young adults before and after seasonal influenza vaccination

artículo científico publicado en 2016

Mucosal immune responses predict clinical outcomes during influenza infection independently of age and viral load.

artículo científico publicado en 2014

NFkappaB negatively regulates interferon-induced gene expression and anti-influenza activity.

artículo científico

Neonatal CD8 T-cell hierarchy is distinct from adults and is influenced by intrinsic T cell properties in respiratory syncytial virus infected mice

artículo científico publicado en 2011

Neuroblastoma Formation Requires Unconventional CD4 T Cells and Arginase-1-Dependent Myeloid Cells

artículo científico publicado en 2021

New Approaches in Immunotherapy

artículo científico publicado en 2010

New advances in CMV and immunosenescence

artículo científico publicado en 2014

New fronts emerge in the influenza cytokine storm

artículo científico

Non-oncogenic Acute Viral Infections Disrupt Anti-cancer Responses and Lead to Accelerated Cancer-Specific Host Death.

artículo científico publicado en 2016

Non-random lymphocyte distribution among virus-infected cells of the respiratory tract.

artículo científico publicado en 2013

Nucleotide oligomerization and binding domain 2-dependent dendritic cell activation is necessary for innate immunity and optimal CD8+ T Cell responses to influenza A virus infection

artículo científico publicado en 2014

Oseltamivir Prophylaxis Reduces Inflammation and Facilitates Establishment of Cross-Strain Protective T Cell Memory to Influenza Viruses

artículo científico publicado en 2015

Overlapping Peptides Elicit Distinct CD8+ T Cell Responses following Influenza A Virus Infection

scientific article published on 31 August 2020

Paired TCRαβ analysis of virus-specific CD8(+) T cells exposes diversity in a previously defined 'narrow' repertoire

artículo científico publicado en 2015

Paired analysis of TCRα and TCRβ chains at the single-cell level in mice

artículo científico publicado en 2010

Parasite-secreted products regulate the host response to larval Taenia crassiceps

article

Pause on avian flu transmission research

artículo científico publicado en 2012

Pediatric patients with acute lymphoblastic leukemia generate abundant and functional neoantigen-specific CD8+ T cell responses

scientific article published on 01 June 2019

Physiological numbers of CD4+ T cells generate weak recall responses following influenza virus challenge

artículo científico publicado en 2010

Primary CTL response magnitude in mice is determined by the extent of naive T cell recruitment and subsequent clonal expansion

artículo científico publicado en 2010

Protective Efficacy of Cross-Reactive CD8+ T Cells Recognising Mutant Viral Epitopes Depends on Peptide-MHC-I Structural Interactions and T Cell Activation Threshold

artículo científico publicado en 2010

Protective memory responses are modulated by priming events prior to challenge.

artículo científico publicado en 2009

Publisher Correction: Exuberant fibroblast activity compromises lung function via ADAMTS4

artículo científico publicado en 2020

Quantifiable predictive features define epitope-specific T cell receptor repertoires

artículo científico publicado en 2017

Quantification of epitope abundance reveals the effect of direct and cross-presentation on influenza CTL responses

artículo científico publicado en 2019

RIPK3 Activates Parallel Pathways of MLKL-Driven Necroptosis and FADD-Mediated Apoptosis to Protect against Influenza A Virus.

artículo científico publicado en 2016

Rapid cloning, expression, and functional characterization of paired αβ and γδ T-cell receptor chains from single-cell analysis.

artículo científico publicado en 2016

Receptor interacting protein kinase 2-mediated mitophagy regulates inflammasome activation during virus infection

artículo científico publicado en 2013

Recovery from severe H7N9 disease is associated with diverse response mechanisms dominated by CD8⁺ T cells

artículo científico publicado en 2015

Reproducible selection of high avidity CD8+ T-cell clones following secondary acute virus infection

scientific article published on 13 January 2014

Respiratory Mucosal Proteome Quantification in Human Influenza Infections

artículo científico publicado en 2016

Respiratory epithelial cells in innate immunity to influenza virus infection

artículo científico publicado en 2010

Respiratory tract epithelial cells express retinaldehyde dehydrogenase ALDH1A and enhance IgA production by stimulated B cells in the presence of vitamin A.

artículo científico publicado en 2014

Retinol binding protein and vitamin D associations with serum antibody isotypes, serum influenza virus-specific neutralizing activities and airway cytokine profiles

artículo científico publicado en 2015

Rules to 'prime' by.

artículo científico publicado en 2009

SNP-mediated disruption of CTCF binding at the IFITM3 promoter is associated with risk of severe influenza in humans

artículo científico publicado en 2017

Screening monoclonal antibodies for cross-reactivity in the ferret model of influenza infection

artículo científico publicado en 2008

Seasonal influenza vaccination is the strongest correlate of cross-reactive antibody responses in migratory bird handlers.

artículo científico publicado en 2014

Severe Influenza Is Characterized by Prolonged Immune Activation: Results From the SHIVERS Cohort Study

scholarly article

Simulation modelling for immunologists

scientific article published on 05 December 2019

Single-Cell Analysis of T-Cell Receptor αβ Repertoire

artículo científico publicado en 2015

Stress Kinase GCN2 Controls the Proliferative Fitness and Trafficking of Cytotoxic T Cells Independent of Environmental Amino Acid Sensing

artículo científico publicado en 2016

Structure-based design of a quadrivalent fusion glycoprotein vaccine for human parainfluenza virus types 1-4

article published in the Proceedings of the National Academy of Sciences of the United States of America

Structure-based design of head-only fusion glycoprotein immunogens for respiratory syncytial virus

artículo científico publicado en 2016

Surveillance states

artículo científico publicado en 2017

T Cell receptor clonotype influences epitope hierarchy in the CD8+ T cell response to respiratory syncytial virus infection.

artículo científico publicado en 2010

T cell immunoglobulin and mucin protein-3 (Tim-3)/Galectin-9 interaction regulates influenza A virus-specific humoral and CD8 T-cell responses.

artículo científico publicado en 2011

T cell receptor αβ diversity inversely correlates with pathogen-specific antibody levels in human cytomegalovirus infection

artículo científico publicado en 2012

T<sub>RH</sub> cells, helpers making an impact in their local community

artículo científico publicado en 2021

TCR meta-clonotypes for biomarker discovery with tcrdist3: quantification of public, HLA-restricted TCR biomarkers of SARS-CoV-2 infection

artículo científico publicado en 2020

TNF/iNOS-producing dendritic cells are the necessary evil of lethal influenza virus infection.

artículo científico publicado en 2009

Targeted Immunosuppression Distinguishes COVID-19 from Influenza in Moderate and Severe Disease

artículo científico publicado en 2020

Targeting Metabolic Reprogramming by Influenza Infection for Therapeutic Intervention

artículo científico publicado en 2017

Targeting phospholipase D in cancer, infection and neurodegenerative disorders

artículo científico publicado en 2017

Targeting the spliceosome through RBM39 degradation results in exceptional responses in high-risk neuroblastoma models

artículo científico publicado en 2021

Terminal deoxynucleotidyltransferase is required for the establishment of private virus-specific CD8+ TCR repertoires and facilitates optimal CTL responses

artículo científico publicado en 2008

The Role of Extracellular Histones in Influenza Virus Pathogenesis

artículo científico publicado en 2017

The TNF Superfamily Molecule LIGHT Promotes the Generation of Circulating and Lung-Resident Memory CD8 T Cells following an Acute Respiratory Virus Infection

artículo científico publicado en 2018

The human side of influenza

artículo científico publicado el 23 de febrero de 2012

The intracellular sensor NLRP3 mediates key innate and healing responses to influenza A virus via the regulation of caspase-1

artículo científico publicado en 2009

The kinase mTOR modulates the antibody response to provide cross-protective immunity to lethal infection with influenza virus.

artículo científico publicado en 2013

The neoepitope landscape in pediatric cancers.

artículo científico

The two faces of heterologous immunity: protection or immunopathology

artículo científico publicado en 2013

Towards integrating extracellular matrix and immunological pathways.

artículo científico publicado en 2017

Trans-nodal migration of resident dendritic cells into medullary interfollicular regions initiates immunity to influenza vaccine

artículo científico publicado en 2014

Transcription factor ZNF148 is a negative regulator of human muscle differentiation

artículo científico publicado en 2017

Transmission studies resume for avian flu.

artículo científico publicado en 2013

Trimeric HIV-1-Env Structures Define Glycan Shields from Clades A, B, and G

artículo científico publicado en 2016

Twelve-Month Longitudinal Serology in SARS-CoV-2 Naïve and Experienced Vaccine Recipients and Unvaccinated COVID-19-Infected Individuals

artículo científico publicado en 2022

Two-Component Ferritin Nanoparticles for Multimerization of Diverse Trimeric Antigens.

artículo científico publicado en 2018

Understanding the drivers of MHC restriction of T cell receptors

artículo científico publicado en 2018

VDJdb: a curated database of T-cell receptor sequences with known antigen specificity

artículo científico publicado en 2017

Vaccine-Induced Antibodies that Neutralize Group 1 and Group 2 Influenza A Viruses

artículo científico publicado en 2016

Vascular Permeability Drives Susceptibility to Influenza Infection in a Murine Model of Sickle Cell Disease

artículo científico publicado en 2017

Virus-specific CD8+ T cells in the liver: armed and ready to kill

artículo científico publicado en 2007