Lista de obras - Joaquín M Campos - Dominio Público Uruguay

1H and 13C NMR studies of 2-functionalized 5-(methylsulfonyl)-1-phenyl-1H-indoles

artículo científico publicado en 2007

1H and 13C spectral assignment of symmetrical bis[(4-aminosubstituted)quinolinium] derivatives

artículo científico publicado en 2005

A New Systematization of the Conformational Behavior of Seven-Membered Rings. Isoclinal Anomeric and Related Orientations(1)

scientific article published on 01 January 1997

A synthetic uracil derivative with antitumor activity through decreasing cyclin D1 and Cdk1, and increasing p21 and p27 in MCF-7 cells.

artículo científico publicado en 2006

Alkylated Sesamol Derivatives as Potent Antioxidants

scientific article published on 21 July 2020

An Antioxidant Potential, Quantum-Chemical and Molecular Docking Study of the Major Chemical Constituents Present in the Leaves of Curatella americana Linn

artículo científico publicado en 2018

An In Silico Study of the Antioxidant Ability for Two Caffeine Analogs Using Molecular Docking and Quantum Chemical Methods

artículo científico publicado en 2018

Anti-proliferative activity of 2,6-dichloro-9- or 7-(ethoxycarbonylmethyl)-9H- or 7H-purines against several human solid tumour cell lines.

artículo científico publicado en 2014

Anticancer activity and cDNA microarray studies of a (RS)-1,2,3,5-tetrahydro-4,1-benzoxazepine-3-yl]-6-chloro-9H-purine, and an acyclic (RS)-O,N-acetalic 6-chloro-7H-purine.

artículo científico publicado en 2011

Anticancer activity of (1,2,3,5-tetrahydro-4,1-benzoxazepine-3-yl)-pyrimidines and -purines against the MCF-7 cell line: Preliminary cDNA microarray studies.

artículo científico publicado en 2008

Antiproliferative activity, cell-cycle dysregulation, and cellular differentiation: salicyl- and catechol-derived acyclic 5-fluorouracil O,N-acetals against breast cancer cells

artículo científico publicado en 2007

Antitumoural properties of benzannelated seven-membered 5-fluorouracil derivatives and related open analogues. Molecular markers for apoptosis and cell cycle dysregulation.

artículo científico publicado en 2005

Bispyridinium cyclophanes: novel templates for human choline kinase inhibitors

artículo científico publicado en 2003

Bozepinib, a novel small antitumor agent, induces PKR-mediated apoptosis and synergizes with IFNα triggering apoptosis, autophagy and senescence

artículo científico publicado en 2013

Choline kinase inhibitors as a novel approach for antiproliferative drug design

artículo científico publicado en 1997

Choline kinase inhibitory effect and antiproliferative activity of new 1,1',1"-(benzene-1,3,5-triylmethylene)tris[4-[(disubstituted)amino]pyridinium] tribromides

artículo científico publicado en 2003

Conformational dynamics of a bispyridinium cyclophane

artículo científico publicado en 2003

Design, syntheses, biological evaluation, and docking studies of 2-substituted 5-methylsulfonyl-1-phenyl-1H-indoles: potent and selective in vitro cyclooxygenase-2 inhibitors

artículo científico publicado en 2007

Design, synthesis and anti-leishmanial activity of novel symmetrical bispyridinium cyclophanes.

artículo científico publicado en 2014

From 5-fluorouracil acyclonucleosides to benzo-fused six- and seven-membered rings linked to pyrimidine and purine bases: the shift from differentiating anticancer agents to apoptotic inducers

scientific article published on 01 October 2008

From a classic approach in cancer chemotherapy towards differentiation therapy: acyclic and cyclic seven-membered 5-fluorouracil O,N-acetals.

artículo científico publicado en 2000

GR-891: a novel 5-fluorouracil acyclonucleoside prodrug for differentiation therapy in rhabdomyosarcoma cells

artículo científico publicado en 1999

Growth inhibition, G(1)-arrest, and apoptosis in MCF-7 human breast cancer cells by novel highly lipophilic 5-fluorouracil derivatives

artículo científico publicado en 2004

HER2-signaling pathway, JNK and ERKs kinases, and cancer stem-like cells are targets of Bozepinib small compound.

artículo científico publicado en 2014

Hierarchical Virtual Screening of Potential Insectides Inhibitors of Acetylcholinesterase and Juvenile Hormone from Temephos

artículo científico publicado en 2019

Homodimeric bis-quaternary heterocyclic ammonium salts as potent acetyl- and butyrylcholinesterase inhibitors: a systematic investigation of the influence of linker and cationic heads over affinity and selectivity

artículo científico publicado en 2011

Identification of New Inhibitors with Potential Antitumor Activity from Polypeptide Structures via Hierarchical Virtual Screening

scientific article published on 14 August 2019

Identification of Novel Chemical Entities for Adenosine Receptor Type 2A Using Molecular Modeling Approaches

scientific article published on 10 March 2020

Identification of Potential COX-2 Inhibitors for the Treatment of Inflammatory Diseases Using Molecular Modeling Approaches

artículo científico publicado en 2020

Identification of Potential Inhibitors from Pyriproxyfen with Insecticidal Activity by Virtual Screening

scientific article published on 25 January 2019

Identification of Potential Insect Growth Inhibitor against Aedes aegypti: A Bioinformatics Approach

artículo científico publicado en 2022

Identification of novel cyclooxygenase-2 selective inhibitors using pharmacophore models

artículo científico publicado en 2002

In Silico Evaluation of Ibuprofen and Two Benzoylpropionic Acid Derivatives with Potential Anti-Inflammatory Activity

scientific article published on 15 April 2019

In Silico Study to Identify New Antituberculosis Molecules from Natural Sources by Hierarchical Virtual Screening and Molecular Dynamics Simulations

artículo científico publicado en 2019

Influence of the linker in bispyridium compounds on the inhibition of human choline kinase

artículo científico publicado en 2004

Inhibition of choline kinase as a specific cytotoxic strategy in oncogene-transformed cells.

artículo científico publicado en 2003

Inhibition of immune complex-mediated neutrophil oxidative metabolism: a pharmacophore model for 3-phenylcoumarin derivatives using GRIND-based 3D-QSAR and 2D-QSAR procedures

artículo científico publicado en 2007

Insight into the inhibition of human choline kinase: homology modeling and molecular dynamics simulations

artículo científico publicado en 2006

LUMO energy of model compounds of bispyridinium compounds as an index for the inhibition of choline kinase

artículo científico publicado en 2001

New (RS)-benzoxazepin-purines with antitumour activity: The chiral switch from (RS)-2,6-dichloro-9-[1-(p-nitrobenzenesulfonyl)-1,2,3,5-tetrahydro-4,1-benzoxazepin-3-yl]-9H-purine.

artículo científico publicado en 2010

Preclinical characterization of RSM-932A, a novel anticancer drug targeting the human choline kinase alpha, an enzyme involved in increased lipid metabolism of cancer cells.

artículo científico publicado en 2014

QSAR of 1,1'-(1,2-ethylenebisbenzyl)bis(4-substitutedpyridinium) dibromides as choline kinase inhibitors: a different approach for antiproliferative drug design

artículo científico publicado en 2000

QSAR-derived choline kinase inhibitors: how rational can antiproliferative drug design be?

artículo científico publicado en 2003

Quantitative structure-activity relationships for a series of symmetrical bisquaternary anticancer compounds

artículo científico publicado en 2002

Selection and preliminary characterization of a Pseudomonas aeruginosa strain mineralizing selected isomers in a branchedchain dodecylbenzenesulphonate mixture.

artículo científico publicado en 1996

Study of the factors that control the ratio of the products between 5-fluorouracil, uracil, and tetrahydrobenzoxazepine O,O-acetals bearing electron-withdrawing groups on the nitrogen atom

artículo científico publicado en 2006

Symmetrical bis-quinolinium compounds: new human choline kinase inhibitors with antiproliferative activity against the HT-29 cell line.

artículo científico publicado en 2005

Synthesis and NMR studies on a C3-symmetrical triquinolina triscationic bicyclophane

scientific article published on 01 July 2005

Synthesis and anticancer activity of (RS)-9-(2,3-dihydro-1,4-benzoxaheteroin-2-ylmethyl)-9H-purines.

artículo científico publicado en 2011

Synthesis and anticancer activity of the (R,S)-benzofused 1,5-oxathiepine moiety tethered to purines through alkylidenoxy linkers.

artículo científico publicado en 2011

Synthesis, biological activity, and quantitative structure-activity relationship study of azanaphthalimide and arylnaphthalimide derivatives

artículo científico publicado en 2004

The chemotherapeutic drug 5-fluorouracil promotes PKR-mediated apoptosis in a p53-independent manner in colon and breast cancer cells

artículo científico publicado en 2011

Toward of Safer Phenylbutazone Derivatives by Exploration of Toxicity Mechanism

article

Towards a model for the inhibition of choline kinase by a new type of inhibitor.

artículo científico publicado en 2004

Two tautomeric polymorphs of 2,6-dichloropurine

artículo científico publicado en 2011

Lista de obras de Joaquín M Campos

1H and 13C NMR studies of 2-functionalized 5-(methylsulfonyl)-1-phenyl-1H-indoles

1H and 13C spectral assignment of symmetrical bis[(4-aminosubstituted)quinolinium] derivatives

A New Systematization of the Conformational Behavior of Seven-Membered Rings. Isoclinal Anomeric and Related Orientations(1)

A synthetic uracil derivative with antitumor activity through decreasing cyclin D1 and Cdk1, and increasing p21 and p27 in MCF-7 cells.

Alkylated Sesamol Derivatives as Potent Antioxidants

An Antioxidant Potential, Quantum-Chemical and Molecular Docking Study of the Major Chemical Constituents Present in the Leaves of Curatella americana Linn

An In Silico Study of the Antioxidant Ability for Two Caffeine Analogs Using Molecular Docking and Quantum Chemical Methods

Anti-proliferative activity of 2,6-dichloro-9- or 7-(ethoxycarbonylmethyl)-9H- or 7H-purines against several human solid tumour cell lines.

Anticancer activity and cDNA microarray studies of a (RS)-1,2,3,5-tetrahydro-4,1-benzoxazepine-3-yl]-6-chloro-9H-purine, and an acyclic (RS)-O,N-acetalic 6-chloro-7H-purine.

Anticancer activity of (1,2,3,5-tetrahydro-4,1-benzoxazepine-3-yl)-pyrimidines and -purines against the MCF-7 cell line: Preliminary cDNA microarray studies.

Antiproliferative activity, cell-cycle dysregulation, and cellular differentiation: salicyl- and catechol-derived acyclic 5-fluorouracil O,N-acetals against breast cancer cells

Antitumoural properties of benzannelated seven-membered 5-fluorouracil derivatives and related open analogues. Molecular markers for apoptosis and cell cycle dysregulation.

Bispyridinium cyclophanes: novel templates for human choline kinase inhibitors

Bozepinib, a novel small antitumor agent, induces PKR-mediated apoptosis and synergizes with IFNα triggering apoptosis, autophagy and senescence

Choline kinase inhibitors as a novel approach for antiproliferative drug design

Choline kinase inhibitory effect and antiproliferative activity of new 1,1',1"-(benzene-1,3,5-triylmethylene)tris[4-[(disubstituted)amino]pyridinium] tribromides

Conformational dynamics of a bispyridinium cyclophane

Design, syntheses, biological evaluation, and docking studies of 2-substituted 5-methylsulfonyl-1-phenyl-1H-indoles: potent and selective in vitro cyclooxygenase-2 inhibitors

Design, synthesis and anti-leishmanial activity of novel symmetrical bispyridinium cyclophanes.

From 5-fluorouracil acyclonucleosides to benzo-fused six- and seven-membered rings linked to pyrimidine and purine bases: the shift from differentiating anticancer agents to apoptotic inducers

From a classic approach in cancer chemotherapy towards differentiation therapy: acyclic and cyclic seven-membered 5-fluorouracil O,N-acetals.

GR-891: a novel 5-fluorouracil acyclonucleoside prodrug for differentiation therapy in rhabdomyosarcoma cells

Growth inhibition, G(1)-arrest, and apoptosis in MCF-7 human breast cancer cells by novel highly lipophilic 5-fluorouracil derivatives

HER2-signaling pathway, JNK and ERKs kinases, and cancer stem-like cells are targets of Bozepinib small compound.

Hierarchical Virtual Screening of Potential Insectides Inhibitors of Acetylcholinesterase and Juvenile Hormone from Temephos

Homodimeric bis-quaternary heterocyclic ammonium salts as potent acetyl- and butyrylcholinesterase inhibitors: a systematic investigation of the influence of linker and cationic heads over affinity and selectivity

Identification of New Inhibitors with Potential Antitumor Activity from Polypeptide Structures via Hierarchical Virtual Screening

Identification of Novel Chemical Entities for Adenosine Receptor Type 2A Using Molecular Modeling Approaches

Identification of Potential COX-2 Inhibitors for the Treatment of Inflammatory Diseases Using Molecular Modeling Approaches

Identification of Potential Inhibitors from Pyriproxyfen with Insecticidal Activity by Virtual Screening

Identification of Potential Insect Growth Inhibitor against Aedes aegypti: A Bioinformatics Approach

Identification of novel cyclooxygenase-2 selective inhibitors using pharmacophore models

In Silico Evaluation of Ibuprofen and Two Benzoylpropionic Acid Derivatives with Potential Anti-Inflammatory Activity

In Silico Study to Identify New Antituberculosis Molecules from Natural Sources by Hierarchical Virtual Screening and Molecular Dynamics Simulations

Influence of the linker in bispyridium compounds on the inhibition of human choline kinase

Inhibition of choline kinase as a specific cytotoxic strategy in oncogene-transformed cells.

Inhibition of immune complex-mediated neutrophil oxidative metabolism: a pharmacophore model for 3-phenylcoumarin derivatives using GRIND-based 3D-QSAR and 2D-QSAR procedures

Insight into the inhibition of human choline kinase: homology modeling and molecular dynamics simulations

LUMO energy of model compounds of bispyridinium compounds as an index for the inhibition of choline kinase

New (RS)-benzoxazepin-purines with antitumour activity: The chiral switch from (RS)-2,6-dichloro-9-[1-(p-nitrobenzenesulfonyl)-1,2,3,5-tetrahydro-4,1-benzoxazepin-3-yl]-9H-purine.

Preclinical characterization of RSM-932A, a novel anticancer drug targeting the human choline kinase alpha, an enzyme involved in increased lipid metabolism of cancer cells.

QSAR of 1,1'-(1,2-ethylenebisbenzyl)bis(4-substitutedpyridinium) dibromides as choline kinase inhibitors: a different approach for antiproliferative drug design

QSAR-derived choline kinase inhibitors: how rational can antiproliferative drug design be?

Quantitative structure-activity relationships for a series of symmetrical bisquaternary anticancer compounds

Selection and preliminary characterization of a Pseudomonas aeruginosa strain mineralizing selected isomers in a branchedchain dodecylbenzenesulphonate mixture.

Study of the factors that control the ratio of the products between 5-fluorouracil, uracil, and tetrahydrobenzoxazepine O,O-acetals bearing electron-withdrawing groups on the nitrogen atom

Symmetrical bis-quinolinium compounds: new human choline kinase inhibitors with antiproliferative activity against the HT-29 cell line.

Synthesis and NMR studies on a C3-symmetrical triquinolina triscationic bicyclophane

Synthesis and anticancer activity of (RS)-9-(2,3-dihydro-1,4-benzoxaheteroin-2-ylmethyl)-9H-purines.

Synthesis and anticancer activity of the (R,S)-benzofused 1,5-oxathiepine moiety tethered to purines through alkylidenoxy linkers.

Synthesis, biological activity, and quantitative structure-activity relationship study of azanaphthalimide and arylnaphthalimide derivatives

The chemotherapeutic drug 5-fluorouracil promotes PKR-mediated apoptosis in a p53-independent manner in colon and breast cancer cells

Toward of Safer Phenylbutazone Derivatives by Exploration of Toxicity Mechanism

Towards a model for the inhibition of choline kinase by a new type of inhibitor.

Two tautomeric polymorphs of 2,6-dichloropurine