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Lista de obras de Leendert A Trouw

A common SNP in the CD40 region is associated with systemic lupus erythematosus and correlates with altered CD40 expression: implications for the pathogenesis

artículo científico publicado en 2011

A mutation in factor I that is associated with atypical hemolytic uremic syndrome does not affect the function of factor I in complement regulation

artículo científico publicado en 2006

A mutation in factor I that is strongly associated with atypical hemolytic uremic syndrome does not affect the function of factor I in complement regulation

A role for mannose-binding lectin dysfunction in generation of autoantibodies in systemic lupus erythematosus

artículo científico publicado en 2004

Activation of the lectin pathway in murine lupus nephritis

scientific article published on 01 April 2005

Age and Sex-Associated Changes of Complement Activity and Complement Levels in a Healthy Caucasian Population

An investigation of the added value of an ACPA multiplex assay in an early rheumatoid arthritis setting.

artículo científico publicado en 2015

Analysis of binding sites on complement factor I that are required for its activity

artículo científico publicado en 2010

Anti-C1q autoantibodies deposit in glomeruli but are only pathogenic in combination with glomerular C1q-containing immune complexes.

artículo científico publicado en 2004

Anti-C1q autoantibodies in murine lupus nephritis

artículo científico publicado en 2004

Anti-C1q autoantibodies, novel tests, and clinical consequences

artículo científico publicado en 2013

Anti-CarP antibodies in two large cohorts of patients with rheumatoid arthritis and their relationship to genetic risk factors, cigarette smoking and other autoantibodies.

artículo científico publicado en 2014

Anti-carbamylated protein (anti-CarP) antibodies precede the onset of rheumatoid arthritis

artículo científico publicado en 2013

Anti-carbamylated protein antibodies are present in arthralgia patients and predict the development of rheumatoid arthritis

artículo científico publicado en 2013

Anti-carbamylated protein antibodies are present prior to rheumatoid arthritis and are associated with its future diagnosis.

artículo científico publicado en 2015

Anti-carbamylated protein antibodies in rheumatoid arthritis patients of Asian descent: Fig. 1

article

Anti-carbamylated protein antibodies in the pre-symptomatic phase of rheumatoid arthritis, their relationship with multiple anti-citrulline peptide antibodies and association with radiological damage

artículo científico publicado en 2015

Anti-carbamylated protein antibodies precede disease onset in monkeys with collagen-induced arthritis

artículo científico publicado en 2017

Anti-carbamylated protein antibodies: a specific hallmark for rheumatoid arthritis. Comparison to conditions known for enhanced carbamylation; renal failure, smoking and chronic inflammation

artículo científico publicado en 2016

Anti-carbamylated protein antibodies: are they useful for the diagnosis of rheumatoid arthritis?

artículo científico publicado en 2020

Anti-citrullinated protein antibodies (ACPA) in early rheumatoid arthritis.

artículo científico publicado en 2011

Anti-citrullinated protein antibodies acquire a pro-inflammatory Fc glycosylation phenotype prior to the onset of rheumatoid arthritis

artículo científico publicado en 2013

Anti-citrullinated protein antibodies contribute to platelet activation in rheumatoid arthritis.

artículo científico publicado en 2015

Anti-citrullinated protein antibodies have a low avidity compared with antibodies against recall antigens

artículo científico publicado en 2010

Anti-citrullinated protein antibodies in the diagnosis of rheumatoid arthritis (RA): diagnostic performance of automated anti-CCP-2 and anti-CCP-3 antibodies assays

artículo científico publicado en 2017

Anti-cyclic citrullinated peptide antibodies are a collection of anti-citrullinated protein antibodies and contain overlapping and non-overlapping reactivities

artículo científico publicado en 2010

Anti-cyclic citrullinated peptide antibodies from rheumatoid arthritis patients activate complement via both the classical and alternative pathways

artículo científico publicado en 2009

Antibodies against carbamylated proteins and cyclic citrullinated peptides in systemic lupus erythematosus: results from two well-defined European cohorts.

artículo científico publicado en 2016

Antibodies specific for carbamylated proteins precede the onset of clinical symptoms in mice with collagen induced arthritis

artículo científico publicado en 2014

Antibody response against the glomerular basement membrane protein agrin in patients with transplant glomerulopathy

artículo científico publicado en 2005

Anticarbamylated protein (anti-CarP) antibodies are present in sera of juvenile idiopathic arthritis (JIA) patients

artículo científico publicado en 2013

Anticarbamylated protein antibodies are associated with long-term disability and increased disease activity in patients with early inflammatory arthritis: results from the Norfolk Arthritis Register.

artículo científico publicado en 2015

Anticarbamylated protein antibodies can be detected in animal models of arthritis that require active involvement of the adaptive immune system

artículo científico publicado en 2015

Anticitrullinated protein antibodies and rheumatoid factor are associated with increased mortality but with different causes of death in patients with rheumatoid arthritis: a longitudinal study in three European cohorts

artículo científico publicado en 2016

Arthritis autoantibodies in individuals without rheumatoid arthritis: follow-up data from a Dutch population-based cohort (Lifelines)

artículo científico publicado en 2020

Association of anti-carbamylated protein antibodies with long-term disability and increased disease activity in patients with early inflammatory arthritis: results from the Norfolk Arthritis Register.

artículo científico publicado en 2015

Autoantibodies against complement components and functional consequences.

artículo científico

Autoantibodies against mannose-binding lectin in systemic lupus erythematosus

artículo científico publicado en 2003

Autoantibodies recognizing carbamylated proteins are present in sera of patients with rheumatoid arthritis and predict joint damage.

artículo científico publicado en 2011

Autoantibodies to complement components.

artículo científico publicado en 2001

Autoantibody testing to predict response to therapy in RA

article

Avidity maturation of anti-citrullinated protein antibodies in rheumatoid arthritis

artículo científico publicado en 2012

Baseline autoantibody profile in rheumatoid arthritis is associated with early treatment response but not long-term outcomes.

artículo científico publicado en 2018

Beyond citrullination: other post-translational protein modifications in rheumatoid arthritis.

artículo científico publicado en 2017

Biomarkers for rheumatoid and psoriatic arthritis.

artículo científico

Both complement and IgG fc receptors are required for development of attenuated antiglomerular basement membrane nephritis in mice

artículo científico publicado en 2009

Breach of autoreactive B cell tolerance by post-translationally modified proteins

artículo científico publicado en 2017

C-reactive protein in myocardial infarction binds to circulating microparticles but is not associated with complement activation

article

C1q Deficiency and Neuropsychiatric Systemic Lupus Erythematosus

artículo científico publicado en 2016

C1q, antibodies and anti-C1q autoantibodies.

artículo científico

C1q-Dependent Dendritic Cell Cross-Presentation of In Vivo-Formed Antigen-Antibody Complexes

artículo científico publicado en 2017

C4b-binding Protein and Factor H Compensate for the Loss of Membrane-bound Complement Inhibitors to Protect Apoptotic Cells against Excessive Complement Attack

artículo científico publicado en 2007

C4b-binding protein binds to necrotic cells and DNA, limiting DNA release and inhibiting complement activation

artículo científico publicado en 2005

C4b-binding protein in Alzheimer's disease: Binding to Aβ1–42 and to dead cells

artículo científico publicado en 2008

C4b-binding protein is present in affected areas of myocardial infarction during the acute inflammatory phase and covers a larger area than C3.

artículo científico publicado en 2008

Carbamylation and antibodies against carbamylated proteins in autoimmunity and other pathologies

artículo científico

Carbamylation reduces the capacity of IgG for hexamerization and complement activation

artículo científico publicado en 2020

Circulating plasmablasts/plasmacells as a source of anticitrullinated protein antibodies in patients with rheumatoid arthritis

artículo científico publicado en 2013

Citrullinated peptide dendritic cell immunotherapy in HLA risk genotype–positive rheumatoid arthritis patients

article

Closing the serological gap: promising novel biomarkers for the early diagnosis of rheumatoid arthritis

artículo científico

Complement Activation in Patients With Diabetic Nephropathy.

artículo científico publicado en 2017

Complement Component C1q as Serum Biomarker to Detect Active Tuberculosis

artículo científico publicado en 2018

Complement activation and inhibition: a delicate balance.

artículo científico publicado en 2009

Complement activation and regulation in rheumatic disease

scientific article published on 01 October 2019

Complement activation by (auto-) antibodies.

artículo científico publicado en 2011

Complement activation in Glioblastoma multiforme pathophysiology: evidence from serum levels and presence of complement activation products in tumor tissue

artículo científico publicado en 2014

Complement and renal disease.

artículo científico publicado en 2003

Complement component C1q as serum biomarker to detect active tuberculosis

scientific article published in 2018

Complement inhibitor C4b-binding protein in primary Sjögren's syndrome and its association with other disease markers

artículo científico publicado en 2009

Complement levels and anti-C1q autoantibodies in patients with neuropsychiatric systemic lupus erythematosus.

artículo científico publicado en 2016

Complement production and regulation by dendritic cells: molecular switches between tolerance and immunity

scientific article published on October 2008

Correction: C4b-binding protein and factor H compensate for the loss of membrane-bound complement inhibitors to protect apoptotic cells against excessive complement attack

artículo científico publicado en 2020

Design and synthesis of 6-phenylnicotinamide derivatives as antagonists of TRPV1.

artículo científico publicado en 2008

Diagnostic and prognostic significance of anti-C1q antibodies in systemic lupus erythematosus.

artículo científico publicado en 2003

Different classes of anti-modified protein antibodies are induced on exposure to antigens expressing only one type of modification

scientific article published on 31 May 2019

Direct binding of C1q to apoptotic cells and cell blebs induces complement activation

artículo científico publicado en 2002

Distinct ACPA fine specificities, formed under the influence of HLA shared epitope alleles, have no effect on radiographic joint damage in rheumatoid arthritis

artículo científico publicado en 2011

Does information on novel identified autoantibodies contribute to predicting the progression from undifferentiated arthritis to rheumatoid arthritis: a study on anti-CarP antibodies as an example

artículo científico publicado en 2018

Excretions/secretions from medicinal larvae (Lucilia sericata) inhibit complement activation by two mechanisms

artículo científico publicado en 2016

Expression and production of the SERPING1-encoded endogenous complement regulator C1-inhibitor in multiple cohorts of tuberculosis patients

scientific article published on 13 March 2020

Extensive glycosylation of ACPA-IgG variable domains modulates binding to citrullinated antigens in rheumatoid arthritis.

artículo científico publicado en 2015

Factor H Autoantibodies in Patients with Antiphospholipid Syndrome and Thrombosis

artículo científico publicado en 2015

Factor H autoantibodies and deletion of Complement Factor H-Related protein-1 in rheumatic diseases in comparison to atypical hemolytic uremic syndrome

artículo científico publicado en 2012

Five decades of Dutch immunology

artículo científico publicado en 2014

Genetic variants in the region of the C1q genes are associated with rheumatoid arthritis.

artículo científico publicado en 2013

Genetic, molecular and functional analyses of complement factor I deficiency

artículo científico publicado en 2009

Glomerular C4d deposition can precede the development of focal segmental glomerulosclerosis

scientific article published on 16 May 2019

Glomerular deposition of C1q and anti-C1q antibodies in mice following injection of antimouse C1q antibodies

artículo científico publicado en 2003

Glycan profiling of anti-citrullinated protein antibodies isolated from human serum and synovial fluid

artículo científico publicado en 2010

HLA-B*08 identified as the most associated MHC locus for anti-carbamylated protein antibody-positive/anti-CCP-negative rheumatoid arthritis

scientific article published on 31 December 2020

Human neutrophil peptide-1 inhibits both the classical and the lectin pathway of complement activation

scientific article published on 19 April 2007

Identification of Lifelines participants at high risk for development of rheumatoid arthritis

article

Identification of a novel non-coding mutation in C1qB in a Dutch child with C1q deficiency associated with recurrent infections.

artículo científico publicado en 2014

Identification of carbamylated alpha 1 anti-trypsin (A1AT) as an antigenic target of anti-CarP antibodies in patients with rheumatoid arthritis

artículo científico publicado en 2017

Immune deposition of C1q and anti-C1q antibodies in the kidney is dependent on the presence of glomerular IgG

scientific article published on 01 December 2003

In RA, becoming seronegative over the first year of treatment does not translate to better chances of drug-free remission

artículo científico publicado en 2018

In rheumatoid arthritis, changes in autoantibody levels reflect intensity of immunosuppression, not subsequent treatment response

scholarly article by Emma C de Moel et al published 18 January 2019 in Arthritis Research and Therapy

Infiltrating dendritic cells contribute to local synthesis of C1q in murine and human lupus nephritis

artículo científico publicado en 2010

Inverse correlation between serum complement component C1q levels and whole blood type-1 interferon signature in active tuberculosis and QuantiFERON-positive uveitis: implications for diagnosis

artículo científico publicado en 2020

Long-term follow-up of patients with anti-cyclic citrullinated peptide antibody-positive connective tissue disease: a retrospective observational study including information on the HLA-DRB1 allele and citrullination dependency

artículo científico publicado en 2020

Low-avidity anticitrullinated protein antibodies (ACPA) are associated with a higher rate of joint destruction in rheumatoid arthritis.

artículo científico publicado en 2013

MRI-detected osteitis is not associated with the presence or level of ACPA alone, but with the combined presence of ACPA and RF.

artículo científico publicado en 2016

Marked variability in clinical presentation and outcome of patients with C1q immunodeficiency

artículo científico publicado en 2015

Mass-spectrometric identification of carbamylated proteins present in the joints of rheumatoid arthritis patients and controls

artículo científico publicado en 2020

Maturation of dendritic cells abrogates C1q production in vivo and in vitro

artículo científico publicado en 2004

Molecular and functional analysis of complement factor I mutations in atypical haemolytic uraemic syndrome patients

scholarly article by Sara C. Nilsson et al published October 2008 in Molecular Immunology

Mutations in complement factor I as found in atypical hemolytic uremic syndrome lead to either altered secretion or altered function of factor I

artículo científico publicado en 2010

New biomarkers in rheumatoid arthritis

artículo científico publicado el 1 de noviembre de 2012

Novel genetic association of theVTCN1region with rheumatoid arthritis

artículo científico publicado en 2012

Pitfalls in the detection of citrullination and carbamylation

artículo científico publicado en 2017

Predictive factors of radiological progression after 2 years of remission-steered treatment in early arthritis patients: a post hoc analysis of the IMPROVED study

artículo científico publicado en 2016

Presence of anticitrullinated protein antibodies in a large population-based cohort from the Netherlands.

artículo científico publicado en 2017

Production of complement components by cells of the immune system.

artículo científico publicado en 2017

Properdin binds to late apoptotic and necrotic cells independently of C3b and regulates alternative pathway complement activation

artículo científico publicado en 2008

Recognition of citrullinated and carbamylated proteins by human antibodies: specificity, cross-reactivity and the 'AMC-Senshu' method

artículo científico publicado en 2012

Regulation of complement activation by C-reactive protein: Targeting of the inhibitory activity of C4b-binding protein

Regulation of complement activation by C-reactive protein: targeting of the inhibitory activity of C4b-binding protein

artículo científico publicado en 2006

Renal tubular epithelial cells modulate T-cell responses via ICOS-L and B7-H1.

artículo científico publicado en 2005

Reply

scientific article published on 09 October 2016

Rheumatoid arthritis-associated autoantibodies in non-rheumatoid arthritis patients with mucosal inflammation: a case-control study.

artículo científico publicado en 2015

Rheumatoid factor isotypes in relation to antibodies against citrullinated peptides and carbamylated proteins before the onset of rheumatoid arthritis

artículo científico publicado en 2016

Role of Anti-Carbamylated Protein Antibodies Compared to Anti-Citrullinated Protein Antibodies in Indigenous North Americans With Rheumatoid Arthritis, Their First-Degree Relatives, and Healthy Controls.

artículo científico publicado en 2016

Role of anti-C1q autoantibodies in the pathogenesis of lupus nephritis

artículo científico publicado en 2005

Role of complement and complement regulators in the removal of apoptotic cells.

artículo científico publicado en 2007

Role of complement in innate immunity and host defense.

artículo científico publicado en 2011

Screening for two or three autoantibodies in persons at risk for RA: implications of current data for clinical practice

scientific article published on 01 May 2019

Secretory form of rheumatoid arthritis-associated autoantibodies in serum are mainly of the IgM isotype, suggesting a continuous reactivation of autoantibody responses at mucosal surfaces

scientific article published on 14 August 2018

Serum autoantibodies directed against transglutaminase-2 have a low avidity compared with alloantibodies against gliadin in coeliac disease

artículo científico publicado en 2014

Short article: Absence of serological rheumatoid arthritis biomarkers in inflammatory bowel disease patients with arthropathies

artículo científico publicado en 2016

Smoking is associated with the concurrent presence of multiple autoantibodies in rheumatoid arthritis rather than with anti-citrullinated protein antibodies per se: a multicenter cohort study.

artículo científico publicado en 2016

Specific inhibition of the classical complement pathway by C1q-binding peptides.

artículo científico publicado en 2001

Substitution of the quantitative serological component in the 2010 criteria for RA with qualitative presence of three autoantibodies yields similar performance: response to the article by Regueiro et al

artículo científico publicado en 2020

Systemic and pulmonary C1q as biomarker of progressive disease in experimental non-human primate tuberculosis

scientific article published on 14 April 2020

TRAF1/C5, eNOS, C1q, but not STAT4 and PTPN22 gene polymorphisms are associated with genetic susceptibility to systemic lupus erythematosus in Turkey

artículo científico publicado en 2011

The ACPA recognition profile and subgrouping of ACPA-positive RA patients

artículo científico publicado en 2011

The C4b-binding protein-protein S complex inhibits the phagocytosis of apoptotic cells

artículo científico publicado en 2004

The anti-carbamylated protein antibody response is of overall low avidity despite extensive isotype switching

artículo científico publicado en 2018

The association between anti-carbamylated protein (anti-CarP) antibodies and radiographic progression in early rheumatoid arthritis: a study exploring replication and the added value to ACPA and rheumatoid factor

artículo científico publicado en 2016

The complement system as a potential therapeutic target in rheumatic disease.

artículo científico

The concentration of anticitrullinated protein antibodies in serum and synovial fluid in relation to total immunoglobulin concentrations

artículo científico publicado en 2013

The extensive glycosylation of the ACPA variable domain observed for ACPA-IgG is absent from ACPA-IgM

artículo científico publicado en 2017

The factor H variant associated with age-related macular degeneration (His-384) and the non-disease-associated form bind differentially to C-reactive protein, fibromodulin, DNA, and necrotic cells

artículo científico publicado en 2007

The fine specificity of IgM anti-citrullinated protein antibodies (ACPA) is different from that of IgG ACPA.

artículo científico publicado en 2011

The influence of ACPA status and characteristics on the course of RA.

artículo científico

The interaction between HLA shared epitope alleles and smoking and its contribution to autoimmunity against several citrullinated antigens

artículo científico publicado en 2011

The isotype and IgG subclass distribution of anti-carbamylated protein antibodies in rheumatoid arthritis patients

artículo científico publicado en 2017

The major risk alleles of age-related macular degeneration (AMD) in CFH do not play a major role in rheumatoid arthritis (RA)

artículo científico publicado en 2011

The prevalence of ACPA is lower in rheumatoid arthritis patients with an older age of onset but the composition of the ACPA response appears identical.

artículo científico publicado en 2017

The production and secretion of complement component C1q by human mast cells

artículo científico publicado en 2016

The risk of individual autoantibodies, autoantibody combinations and levels for arthritis development in clinically suspect arthralgia.

artículo científico publicado en 2017

The role of complement activation in autoimmune liver disease

scientific article published on 28 March 2020

The role of complement in antineutrophil cytoplasmic antibody-associated vasculitis

scientific article published on 01 January 2019

The specificity of anti-carbamylated protein antibodies for rheumatoid arthritis in a setting of early arthritis.

artículo científico publicado en 2015

The window of opportunity in ACPA-positive rheumatoid arthritis is not explained by ACPA characteristics

artículo científico publicado en 2011

Triple Positivity for Anti-Citrullinated Protein Autoantibodies, Rheumatoid Factor, and Anti-Carbamylated Protein Antibodies Conferring High Specificity for Rheumatoid Arthritis

artículo científico publicado en 2018

Type I Interferon Gene Response Is Increased in Early and Established Rheumatoid Arthritis and Correlates with Autoantibody Production

artículo científico publicado en 2017

Which elements of the criteria for RA are stable over time?

artículo científico publicado en 2010

[The role of the complement system in the defence against infections and new ways of assessing the activation routes]

scientific article published on 01 November 2004

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