Lista de obras - Stephen J. Tucker - Dominio Público Uruguay

A BEST example of channel structure annotation by molecular simulation.

artículo científico publicado en 2017

A Non-canonical Voltage-Sensing Mechanism Controls Gating in K2P K(+) Channels.

artículo científico publicado en 2016

A dominant-negative mutation in the TRESK potassium channel is linked to familial migraine with aura

artículo científico publicado en 2010

A heuristic derived from analysis of the ion channel structural proteome permits the rapid identification of hydrophobic gates

scientific article published on 24 June 2019

A hydrophobic barrier deep within the inner pore of the TWIK-1 K2P potassium channel

artículo científico publicado en 2014

A lower X-gate in TASK channels traps inhibitors within the vestibule

artículo científico publicado en 2020

A novel KCNA1 mutation identified in an Italian family affected by episodic ataxia type 1

artículo científico publicado en 2008

A novel method for measurement of submembrane ATP concentration

artículo científico publicado en 2000

A pharmacological master key mechanism that unlocks the selectivity filter gate in K+ channels ⬇️

scientific article published on 01 February 2019

A touching case of channel regulation: the ATP-sensitive K+ channel

artículo científico publicado en 1998

Activation and inhibition of K-ATP currents by guanine nucleotides is mediated by different channel subunits.

artículo científico publicado en 1997

Altered functional properties of a missense variant in the TRESK K+ channel (KCNK18) associated with migraine and intellectual disability

scientific article published on 12 May 2020

Assignment of KATP-1, the cardiac ATP-sensitive potassium channel gene (KCNJ5), to human chromosome 11q24

artículo científico publicado en 1995

Asymmetric mechanosensitivity in a eukaryotic ion channel.

artículo científico publicado en 2017

Bilayer-Mediated Structural Transitions Control Mechanosensitivity of the TREK-2 K2P Channel.

artículo científico publicado en 2017

Cloning and functional characterization of a superfamily of microbial inwardly rectifying potassium channels

scientific article published on 04 April 2006

Conformational changes during the gating of a potassium channel revealed by structural mass spectrometry

artículo científico publicado en 2010

Contribution of the central hydrophobic residue in the PXP motif of voltage-dependent K+ channels to S6 flexibility and gating properties

artículo científico publicado en 2009

Control of KirBac3.1 Potassium Channel Gating at the Interface between Cytoplasmic Domains

artículo científico publicado en 2014

Control of pH and PIP2 gating in heteromeric Kir4.1/Kir5.1 channels by H-Bonding at the helix-bundle crossing

artículo científico publicado en 2007

Correction: Dominant-Negative Effect of a Missense Variant in the TASK-2 (KCNK5) K+ Channel Associated with Balkan Endemic Nephropathy

artículo científico publicado en 2016

Crystal Structures of the Extracellular Domain from PepT1 and PepT2 Provide Novel Insights into Mammalian Peptide Transport

artículo científico publicado en 2015

Cystic fibrosis transmembrane conductance regulator-dependent up-regulation of Kir1.1 (ROMK) renal K+ channels by the epithelial sodium channel

artículo científico publicado en 2002

De novo point mutations in patients diagnosed with ataxic cerebral palsy.

artículo científico publicado en 2015

Direct Photoaffinity Labeling of the Kir6.2 Subunit of the ATP-sensitive K+Channel by 8-Azido-ATP

artículo científico publicado en 1999

Direct photoaffinity labeling of Kir6.2 by [gamma-(32)P]ATP-[gamma]4-azidoanilide

artículo científico publicado en 2000

Dynamic role of the tether helix in PIP2-dependent gating of a G protein-gated potassium channel

artículo científico publicado en 2017

Electric Field Induced Wetting of a Hydrophobic Gate in a Model Nanopore Based on the 5-HT 3 Receptor Channel

Electric Field Induced Wetting of a Hydrophobic Gate in a Model Nanopore Based on the 5-HT3 Receptor Channel

artículo científico publicado en 2020

Electronic Polarizability Tunes the Function of the Human Bestrophin 1 Cl − Channel

Functional analysis of missense variants in the TRESK (KCNK18) K channel

artículo científico publicado en 2012

Functional characterisation of missense variations in the Kir4.1 potassium channel (KCNJ10) associated with seizure susceptibility.

artículo científico publicado en 2005

Functional complementation and genetic deletion studies of KirBac channels: activatory mutations highlight gating-sensitive domains

artículo científico publicado en 2010

Genetic Inactivation of Kcnj16 Identifies Kir5.1 as an Important Determinant of Neuronal PCO2/pH Sensitivity ⬇️

artículo científico publicado el 3 de noviembre de 2010

Heteromeric channel formation and Ca(2+)-free media reduce the toxic effect of the weaver Kir 3.2 allele.

artículo científico publicado en 1996

How highly charged anionic lipids bind and regulate ion channels

artículo científico publicado en 2008

Hydrophobic gating in ion channels

artículo científico publicado en 2014

In vitro reconstitution of eukaryotic ion channels using droplet interface bilayers

artículo científico publicado en 2011

Induced Polarization in MD Simulations of the 5HT3 Receptor Channel

artículo científico publicado en 2020

Influence of Electronic Polarization on the Binding of Anions to a Chloride-Pumping Rhodopsin

Influence of effective polarization on ion and water interactions within a biomimetic nanopore

Influence of lipids on the hydrophobic barrier within the pore of the TWIK-1 K2P channel

artículo científico publicado en 2015

Influence of the N terminus on the biophysical properties and pharmacology of TREK1 potassium channels

scientific article published on 07 February 2014

Inhibitory interactions between two inward rectifier K+ channel subunits mediated by the transmembrane domains

artículo científico publicado en 1996

Insights into the structural nature of the transition state in the Kir channel gating pathway

artículo científico publicado en 2014

Intrinsic sensitivity of Kir1.1 (ROMK) to glibenclamide in the absence of SUR2B. Implications for the identity of the renal ATP-regulated secretory K+ channel

artículo científico publicado en 2002

Involvement of the N-terminus of Kir6.2 in the inhibition of the KATP channel by ATP.

artículo científico publicado en 1999

Involvement of the n-terminus of Kir6.2 in coupling to the sulphonylurea receptor

artículo científico publicado en 1999

Inward rectification in KATP channels: a pH switch in the pore.

artículo científico publicado en 1999

Ion Mobility Mass Spectrometry of Two Tetrameric Membrane Protein Complexes Reveals Compact Structures and Differences in Stability and Packing

article

K2P channel gating mechanisms revealed by structures of TREK-2 and a complex with Prozac

artículo científico publicado en 2015

Kir5.1 underlies long-lived subconductance levels in heteromeric Kir4.1/Kir5.1 channels from Xenopus tropicalis

scientific journal article

Long chain CoA esters as competitive antagonists of phosphatidylinositol 4,5-bisphosphate activation in Kir channels

artículo científico publicado en 2005

MgATP activates the beta cell KATP channel by interaction with its SUR1 subunit.

artículo científico publicado en 1998

Modular Design of the Selectivity Filter Pore Loop in a Novel Family of Prokaryotic 'Inward Rectifier' (NirBac) channels

artículo científico publicado en 2015

Molecular Simulations of Hydrophobic Gating of Pentameric Ligand Gated Ion Channels: Insights into Water and Ions

Molecular analysis of ATP-sensitive K channel gating and implications for channel inhibition by ATP.

artículo científico publicado en 1998

Molecular determinants of KATP channel inhibition by ATP.

artículo científico publicado en 1998

Molecular dynamics simulations of inwardly rectifying (Kir) potassium channels: a comparative study

artículo científico publicado en 2007

Molecular simulation studies of hydrophobic gating in nanopores and ion channels

artículo científico publicado en 2015

Multiple sites of interaction between the intracellular domains of an inwardly rectifying potassium channel, Kir6.2.

artículo científico publicado en 2001

NEM modification prevents high-affinity ATP binding to the first nucleotide binding fold of the sulphonylurea receptor, SUR1

artículo científico publicado en 1999

Non-equivalent cooperation between the two nucleotide-binding folds of P-glycoprotein

artículo científico publicado en 1998

Non-equivalent role of TM2 gating hinges in heteromeric Kir4.1/Kir5.1 potassium channels

artículo científico publicado en 2007

Novel phenotype associated with a mutation in the KCNA1(Kv1.1) gene

artículo científico publicado en 2014

Peptide backbone mutagenesis of putative gating hinges in a potassium ion channel

artículo científico publicado en 2008

Publisher Correction: Structure and assembly of calcium homeostasis modulator proteins

artículo científico publicado en 2020

Renal phenotype in mice lacking the Kir5.1 (Kcnj16) K+ channel subunit contrasts with that observed in SeSAME/EAST syndrome.

artículo científico publicado en 2011

Respiratory responses to hypercapnia and hypoxia in mice with genetic ablation of Kir5.1 (Kcnj16).

artículo científico publicado en 2011

Role of receptor protein tyrosine phosphatase alpha (RPTPalpha) and tyrosine phosphorylation in the serotonergic inhibition of voltage-dependent potassium channels

artículo científico publicado en 2000

Selectivity filter instability dominates the low intrinsic activity of the TWIK-1 K2P K+ channel

artículo científico publicado en 2019

Simulation-based prediction of phosphatidylinositol 4,5-bisphosphate binding to an ion channel.

artículo científico publicado en 2012

State-dependent network connectivity determines gating in a K+ channel

artículo científico publicado en 2014

State-independent intracellular access of quaternary ammonium blockers to the pore of TREK-1

artículo científico publicado en 2012

Structural basis for proton coupled cystine transport by cystinosin

Structure and assembly of calcium homeostasis modulator proteins

artículo científico publicado en 2020

Structure of a KirBac potassium channel with an open bundle crossing indicates a mechanism of channel gating

artículo científico publicado en 2012

The effects of stretch activation on ionic selectivity of the TREK-2 K2P K+ channel.

artículo científico publicado en 2017

The interaction of nucleotides with the tolbutamide block of cloned ATP-sensitive K+ channel currents expressed in Xenopus oocytes: a reinterpretation

artículo científico publicado en 1997

The role of lysine 185 in the kir6.2 subunit of the ATP-sensitive channel in channel inhibition by ATP.

artículo científico publicado en 1999

Truncation of Kir6.2 produces ATP-sensitive K+ channels in the absence of the sulphonylurea receptor

artículo científico publicado en 1997

Water Nanoconfined in a Hydrophobic Pore: MD Simulations and Water Models

Water Nanoconfined in a Hydrophobic Pore: Molecular Dynamics Simulations of Transmembrane Protein 175 and the Influence of Water Models

artículo científico publicado en 2021

Water and hydrophobic gates in ion channels and nanopores

artículo científico publicado en 2018

pH dependence of the inwardly rectifying potassium channel, Kir5.1, and localization in renal tubular epithelia

artículo científico publicado en 2000

Lista de obras de Stephen J. Tucker

A BEST example of channel structure annotation by molecular simulation.

A Non-canonical Voltage-Sensing Mechanism Controls Gating in K2P K(+) Channels.

A dominant-negative mutation in the TRESK potassium channel is linked to familial migraine with aura

A heuristic derived from analysis of the ion channel structural proteome permits the rapid identification of hydrophobic gates

A hydrophobic barrier deep within the inner pore of the TWIK-1 K2P potassium channel

A lower X-gate in TASK channels traps inhibitors within the vestibule

A novel KCNA1 mutation identified in an Italian family affected by episodic ataxia type 1

A novel method for measurement of submembrane ATP concentration

A pharmacological master key mechanism that unlocks the selectivity filter gate in K+ channels ⬇️

A touching case of channel regulation: the ATP-sensitive K+ channel

Activation and inhibition of K-ATP currents by guanine nucleotides is mediated by different channel subunits.

Altered functional properties of a missense variant in the TRESK K+ channel (KCNK18) associated with migraine and intellectual disability

Assignment of KATP-1, the cardiac ATP-sensitive potassium channel gene (KCNJ5), to human chromosome 11q24

Asymmetric mechanosensitivity in a eukaryotic ion channel.

Bilayer-Mediated Structural Transitions Control Mechanosensitivity of the TREK-2 K2P Channel.

Cloning and functional characterization of a superfamily of microbial inwardly rectifying potassium channels

Conformational changes during the gating of a potassium channel revealed by structural mass spectrometry

Contribution of the central hydrophobic residue in the PXP motif of voltage-dependent K+ channels to S6 flexibility and gating properties

Control of KirBac3.1 Potassium Channel Gating at the Interface between Cytoplasmic Domains

Control of pH and PIP2 gating in heteromeric Kir4.1/Kir5.1 channels by H-Bonding at the helix-bundle crossing

Correction: Dominant-Negative Effect of a Missense Variant in the TASK-2 (KCNK5) K+ Channel Associated with Balkan Endemic Nephropathy

Crystal Structures of the Extracellular Domain from PepT1 and PepT2 Provide Novel Insights into Mammalian Peptide Transport

Cystic fibrosis transmembrane conductance regulator-dependent up-regulation of Kir1.1 (ROMK) renal K+ channels by the epithelial sodium channel

De novo point mutations in patients diagnosed with ataxic cerebral palsy.

Direct Photoaffinity Labeling of the Kir6.2 Subunit of the ATP-sensitive K+Channel by 8-Azido-ATP

Direct photoaffinity labeling of Kir6.2 by [gamma-(32)P]ATP-[gamma]4-azidoanilide

Dynamic role of the tether helix in PIP2-dependent gating of a G protein-gated potassium channel

Electric Field Induced Wetting of a Hydrophobic Gate in a Model Nanopore Based on the 5-HT 3 Receptor Channel

Electric Field Induced Wetting of a Hydrophobic Gate in a Model Nanopore Based on the 5-HT3 Receptor Channel

Electronic Polarizability Tunes the Function of the Human Bestrophin 1 Cl − Channel

Functional analysis of missense variants in the TRESK (KCNK18) K channel

Functional characterisation of missense variations in the Kir4.1 potassium channel (KCNJ10) associated with seizure susceptibility.

Functional complementation and genetic deletion studies of KirBac channels: activatory mutations highlight gating-sensitive domains

Genetic Inactivation of Kcnj16 Identifies Kir5.1 as an Important Determinant of Neuronal PCO2/pH Sensitivity ⬇️

Heteromeric channel formation and Ca(2+)-free media reduce the toxic effect of the weaver Kir 3.2 allele.

How highly charged anionic lipids bind and regulate ion channels

Hydrophobic gating in ion channels

In vitro reconstitution of eukaryotic ion channels using droplet interface bilayers

Induced Polarization in MD Simulations of the 5HT3 Receptor Channel

Influence of Electronic Polarization on the Binding of Anions to a Chloride-Pumping Rhodopsin

Influence of effective polarization on ion and water interactions within a biomimetic nanopore

Influence of effective polarization on ion and water interactions within a biomimetic nanopore

Influence of lipids on the hydrophobic barrier within the pore of the TWIK-1 K2P channel

Influence of the N terminus on the biophysical properties and pharmacology of TREK1 potassium channels

Inhibitory interactions between two inward rectifier K+ channel subunits mediated by the transmembrane domains

Insights into the structural nature of the transition state in the Kir channel gating pathway

Intrinsic sensitivity of Kir1.1 (ROMK) to glibenclamide in the absence of SUR2B. Implications for the identity of the renal ATP-regulated secretory K+ channel

Involvement of the N-terminus of Kir6.2 in the inhibition of the KATP channel by ATP.

Involvement of the n-terminus of Kir6.2 in coupling to the sulphonylurea receptor

Inward rectification in KATP channels: a pH switch in the pore.

Ion Mobility Mass Spectrometry of Two Tetrameric Membrane Protein Complexes Reveals Compact Structures and Differences in Stability and Packing

K2P channel gating mechanisms revealed by structures of TREK-2 and a complex with Prozac

Kir5.1 underlies long-lived subconductance levels in heteromeric Kir4.1/Kir5.1 channels from Xenopus tropicalis

Long chain CoA esters as competitive antagonists of phosphatidylinositol 4,5-bisphosphate activation in Kir channels

MgATP activates the beta cell KATP channel by interaction with its SUR1 subunit.

Modular Design of the Selectivity Filter Pore Loop in a Novel Family of Prokaryotic 'Inward Rectifier' (NirBac) channels

Molecular Simulations of Hydrophobic Gating of Pentameric Ligand Gated Ion Channels: Insights into Water and Ions

Molecular analysis of ATP-sensitive K channel gating and implications for channel inhibition by ATP.

Molecular determinants of KATP channel inhibition by ATP.

Molecular dynamics simulations of inwardly rectifying (Kir) potassium channels: a comparative study

Molecular simulation studies of hydrophobic gating in nanopores and ion channels

Multiple sites of interaction between the intracellular domains of an inwardly rectifying potassium channel, Kir6.2.

NEM modification prevents high-affinity ATP binding to the first nucleotide binding fold of the sulphonylurea receptor, SUR1

Non-equivalent cooperation between the two nucleotide-binding folds of P-glycoprotein

Non-equivalent role of TM2 gating hinges in heteromeric Kir4.1/Kir5.1 potassium channels

Novel phenotype associated with a mutation in the KCNA1(Kv1.1) gene

Peptide backbone mutagenesis of putative gating hinges in a potassium ion channel

Publisher Correction: Structure and assembly of calcium homeostasis modulator proteins

Renal phenotype in mice lacking the Kir5.1 (Kcnj16) K+ channel subunit contrasts with that observed in SeSAME/EAST syndrome.

Respiratory responses to hypercapnia and hypoxia in mice with genetic ablation of Kir5.1 (Kcnj16).

Role of receptor protein tyrosine phosphatase alpha (RPTPalpha) and tyrosine phosphorylation in the serotonergic inhibition of voltage-dependent potassium channels

Selectivity filter instability dominates the low intrinsic activity of the TWIK-1 K2P K+ channel

Simulation-based prediction of phosphatidylinositol 4,5-bisphosphate binding to an ion channel.

State-dependent network connectivity determines gating in a K+ channel

State-independent intracellular access of quaternary ammonium blockers to the pore of TREK-1

Structural basis for proton coupled cystine transport by cystinosin

Structure and assembly of calcium homeostasis modulator proteins

Structure of a KirBac potassium channel with an open bundle crossing indicates a mechanism of channel gating

The effects of stretch activation on ionic selectivity of the TREK-2 K2P K+ channel.