Lista de obras - John K. Cowell - Dominio Público Uruguay

A Yeast Artificial Chromosome Contig That Spans the RB1-D13S31 Interval on Human Chromosome 13 and Encompasses the Frequently Deleted Region in B-cell Chronic Lymphocytic Leukemia

article

A novel member of the WD-repeat gene family, WDR11, maps to the 10q26 region and is disrupted by a chromosome translocation in human glioblastoma cells.

artículo científico publicado en 2001

A role for p300/CREB binding protein genes in promoting cancer progression in colon cancer cell lines with microsatellite instability

artículo científico publicado en 2004

Aberrant expression of the tumour suppressor gene p53 is very frequent in Wilms' tumours

artículo científico publicado en 1992

Acute progression of BCR-FGFR1 induced murine B-lympho/myeloproliferative disorder suggests involvement of lineages at the pro-B cell stage.

artículo científico publicado en 2012

Analysis of the RB1 gene in children with retinoblastoma having residential connections to West Cumbria, England

artículo científico publicado en 2005

Analysis of wilms tumors using SNP mapping array-based comparative genomic hybridization.

artículo científico publicado en 2011

Application of bacterial artificial chromosome array-based comparative genomic hybridization and spectral karyotyping to the analysis of glioblastoma multiforme

artículo científico publicado en 2004

Application of oligonucleotides arrays for coincident comparative genomic hybridization, ploidy status and loss of heterozygosity studies in human cancers.

artículo científico publicado en 2009

Application of spectral karyotyping to the analysis of the human chromosome complement of interspecies somatic cell hybrids

artículo científico publicado en 2003

Array CGH analysis of pediatric medulloblastomas

artículo científico publicado en 2006

Array comparative genome hybridization analysis of acute lymphoblastic leukaemia and acute megakaryoblastic leukaemia in patients with Down syndrome

artículo científico publicado en 2008

Assignment of four sequence-tagged sites to three subregions of 13q12 using a somatic cell hybrid mapping panel

scientific article published on 01 October 1993

CLCA2 tumour suppressor gene in 1p31 is epigenetically regulated in breast cancer

artículo científico publicado en 2004

Candidate glioblastoma development gene identification using concordance between copy number abnormalities and gene expression level changes.

artículo científico publicado en 2007

Characterization of FAM10A4, a member of the ST13 tumor suppressor gene family that maps to the 13q14.3 region associated with B-Cell leukemia, multiple myeloma, and prostate cancer

artículo científico publicado en 2002

Characterization of the breakpoints in a t(8;13)(p11;q12) translocation from a patient with myeloproliferative disease using fluorescence in situ hybridization

artículo científico publicado en 1998

Chromosome analysis of human neuroblastoma cell line TR14 showing double minutes and an aberration involving chromosome 1.

artículo científico publicado en 1983

Colon carcinoma cells harboring PIK3CA mutations display resistance to growth factor deprivation induced apoptosis.

artículo científico publicado en 2007

Comprehensive analysis of loss of heterozygosity events in glioblastoma using the 100K SNP mapping arrays and comparison with copy number abnormalities defined by BAC array comparative genomic hybridization.

artículo científico publicado en 2008

Constitutional nonsense germline mutations in the RB1 gene detected in patients with early onset unilateral retinoblastoma

artículo científico publicado en 1996

Constitutive Notch pathway activation in murine ZMYM2-FGFR1–induced T-cell lymphomas associated with atypical myeloproliferative disease ⬇️

artículo científico publicado el 28 de abril de 2011

Copy number and gene expression alterations in radiation-induced papillary thyroid carcinoma from chernobyl pediatric patients.

artículo científico publicado en 2010

Critical individual roles of the BCR and FGFR1 kinase domains in BCR-FGFR1-driven stem cell leukemia/lymphoma syndrome

scientific article published on 10 October 2019

DNA methyltransferase 1-mediated CpG methylation of the miR-150-5p promoter contributes to fibroblast growth factor receptor 1-driven leukemogenesis

scientific article published on 18 October 2019

Differential expression of the LGI and SLIT families of genes in human cancer cells

artículo científico publicado en 2005

Direct isolation of human transcribed sequences from yeast artificial chromosomes through the application of RNA fingerprinting

artículo científico publicado en 1997

Distinct molecular signatures in pediatric infratentorial glioblastomas defined by aCGH.

artículo científico publicado en 2010

EagI and NotI linking clones from human chromosomes 11 and Xp.

artículo científico publicado en 1996

Editorial

Epilepsy research gets new guidance

artículo científico publicado en 2002

Evolution of a normal karyotype in a mouse bladder epithelial cell line transformed in vitro

scientific article published on 01 June 1981

Functional interrelationship between the WASF3 and KISS1 metastasis-associated genes in breast cancer cells.

artículo científico publicado en 2011

Gain of 1q is a potential univariate negative prognostic marker for survival in medulloblastoma

artículo científico publicado en 2007

Genetic analysis of Down syndrome-associated heart defects in mice.

artículo científico publicado en 2011

Genetic fingerprinting of the development and progression of T-cell lymphoma in a murine model of atypical myeloproliferative disorder initiated by the ZNF198-fibroblast growth factor receptor-1 chimeric tyrosine kinase.

artículo científico publicado en 2009

Genome wide copy number abnormalities in pediatric medulloblastomas as assessed by array comparative genome hybridization

artículo científico publicado en 2007

Genome-wide aberrations in pancreatic adenocarcinoma.

artículo científico publicado en 2005

Genomic analysis of CD8+ NK/T cell line, 'SRIK-NKL', with array-based CGH (aCGH), SKY/FISH and molecular mapping

artículo científico publicado en 2007

Genomic profiling of myeloid sarcoma by array comparative genomic hybridization

artículo científico publicado en 2005

Germline mutations in the RB1 gene in patients with hereditary retinoblastoma

artículo científico publicado en 1995

HIF1A induces expression of the WASF3 metastasis-associated gene under hypoxic conditions.

artículo científico publicado en 2012

HSP90 and HSP70 Proteins Are Essential for Stabilization and Activation of WASF3 Metastasis-promoting Protein ⬇️

artículo científico publicado el 7 de febrero de 2012

HSPA1A is an important regulator of the stability and function of ZNF198 and its oncogenic derivative, ZNF198-FGFR1.

artículo científico publicado en 2007

Homozygous inactivation of the LGI1 gene results in hypomyelination in the peripheral and central nervous systems.

artículo científico publicado en 2010

Identification and characterisation of constitutional chromosome abnormalities using arrays of bacterial artificial chromosomes.

artículo científico publicado en 2004

Identification of YAC clones for human chromosome 1p32 and physical mapping of the infantile neuronal ceroid lipofuscinosis (INCL) locus

scientific article published on 01 January 1995

Identification of consistent novel submegabase deletions in low-grade oligodendrogliomas using array-based comparative genomic hybridization

artículo científico publicado en 2005

Incorporation of 35 novel gene transcripts into the physical and genetic map of human chromosome 13

scientific article published on 01 April 1996

Induction of the plasminogen activator inhibitor-2 in cells expressing the ZNF198/FGFR1 fusion kinase that is involved in atypical myeloproliferative disease.

artículo científico publicado en 2006

Insulin-like growth factor-II gene expression in Wilms' tumour and embryonic tissues

artículo científico publicado en 1985

Integration of the physical and genetic linkage map for human chromosome 13

scientific article published on 01 June 1995

Investigation of LGI1 as the antigen in limbic encephalitis previously attributed to potassium channels: a case series

artículo científico publicado en 2010

Knockdown of zebrafish Lgi1a results in abnormal development, brain defects and a seizure-like behavioral phenotype

artículo científico publicado en 2010

LGI1, a putative tumor metastasis suppressor gene, controls in vitro invasiveness and expression of matrix metalloproteinases in glioma cells through the ERK1/2 pathway

artículo científico publicado en 2004

Lgi1 null mutant mice exhibit myoclonic seizures and CA1 neuronal hyperexcitability

artículo científico publicado en 2010

Localization of the 8;13 translocation breakpoint associated with myeloproliferative disease to a 1.5 mbp region of chromosome 13

article

Long tandem repeats as a form of genomic copy number variation: structure and length polymorphism of a chromosome 5p repeat in control and schizophrenia populations

artículo científico publicado en 2009

Loss of zebrafish lgi1b leads to hydrocephalus and sensitization to pentylenetetrazol induced seizure-like behavior

artículo científico publicado en 2011

Manipulation of nonsense mediated decay identifies gene mutations in colon cancer Cells with microsatellite instability

artículo científico publicado en 2004

Mass spectrometry identifies LGI1-interacting proteins that are involved in synaptic vesicle function in the human brain

artículo científico publicado en 2009

Mass spectroscopy identifies the splicing-associated proteins, PSF, hnRNP H3, hnRNP A2/B1, and TLS/FUS as interacting partners of the ZNF198 protein associated with rearrangement in myeloproliferative disease

artículo científico publicado en 2005

Molecular characterization of a (1;10)(p22;q21) constitutional translocation from a patient with neuroblastoma

artículo científico publicado en 1995

Molecular characterization of a 7p15-21 homozygous deletion in a Wilms tumor

article

Molecular characterization of the 1p22 breakpoint region spanning the constitutional translocation breakpoint in a neuroblastoma patient with a t(1;10)(p22;q21)

artículo científico publicado en 1998

Molecular characterization of the breakpoint region associated with a constitutional t(2;15)(q34;q26) in a patient with multiple myeloma

artículo científico publicado en 2001

Molecular definition of chromosome translocations involving 10q24 and 19q13 in human malignant glioma cells

artículo científico publicado en 1998

Molecular study of malignant gliomas treated with epidermal growth factor receptor inhibitors: tissue analysis from North American Brain Tumor Consortium Trials 01-03 and 00-01.

artículo científico publicado en 2005

Mutation in the FGFR1 tyrosine kinase domain or inactivation of PTEN is associated with acquired resistance to FGFR inhibitors in FGFR1-driven leukemia/lymphomas.

artículo científico publicado en 2017

NB4S, a member of the TBC1 domain family of genes, is truncated as a result of a constitutional t(1;10)(p22;q21) chromosome translocation in a patient with stage 4S neuroblastoma

artículo científico publicado en 1998

Novel amplicons on the short arm of chromosome 7 identified using high resolution array CGH contain over expressed genes in addition to EGFR in glioblastoma multiforme

artículo científico publicado en 2005

Obtaining DNA from a geographically dispersed cohort of current and former smokers: use of mail-based mouthwash collection and monetary incentives.

artículo científico publicado en 2004

Oncogenic point mutations in exon 20 of the RB1 gene in families showing incomplete penetrance and mild expression of the retinoblastoma phenotype

artículo científico publicado en 1992

Overlay analysis of the oligonucleotide array gene expression profiles and copy number abnormalities as determined by array comparative genomic hybridization in medulloblastomas

artículo científico publicado en 2007

Pediatric primary intramedullary spinal cord glioblastoma

artículo científico publicado en 2010

Phosphorylation of the SSBP2 and ABL proteins by the ZNF198-FGFR1 fusion kinase seen in atypical myeloproliferative disorders as revealed by phosphopeptide-specific MS.

artículo científico publicado en 2009

Ploidy status and copy number aberrations in primary glioblastomas defined by integrated analysis of allelic ratios, signal ratios and loss of heterozygosity using 500K SNP Mapping Arrays

artículo científico publicado en 2008

Ponatinib suppresses the development of myeloid and lymphoid malignancies associated with FGFR1 abnormalities

artículo científico publicado en 2012

Prenatal exclusion of hereditary retinoblastoma

scientific article published on 01 April 1988

Promotion of invasion by mutant RAS is dependent on activation of the WASF3 metastasis promoter gene.

artículo científico publicado en 2017

Rapid detection of allelic losses in brain tumours using microsatellite repeat markers and high-performance liquid chromatography

artículo científico publicado en 2003

Reexpression of LGI1 in glioma cells results in dysregulation of genes implicated in the canonical axon guidance pathway.

artículo científico publicado en 2009

Regional localization of 192 genic markers on human chromosome 1

scientific article published on 01 September 1996

Register of retinoblastoma: preliminary results

scientific article published on 01 January 1988

Selective inactivation of LGI1 in neuronal precursor cells leads to cortical dysplasia in mice

scientific article published on 24 December 2018

Src Activation Plays an Important Key Role in Lymphomagenesis Induced by FGFR1 Fusion Kinases ⬇️

artículo científico publicado el 21 de septiembre de 2011

TTC4, a novel human gene containing the tetratricopeptide repeat and mapping to the region of chromosome 1p31 that is frequently deleted in sporadic breast cancer.

artículo científico publicado en 1999

Telomeres and telomerase in ageing and cancer

scientific article published on 01 April 1999

The EVI5 TBC domain provides the GTPase-activating protein motif for RAB11.

artículo científico publicado en 2006

The TACC domain identifies a family of centrosomal proteins that can interact with microtubules

artículo científico publicado en 2000

The oncogenic fusion protein-tyrosine kinase ZNF198/fibroblast growth factor receptor-1 has signaling function comparable with interleukin-6 cytokine receptors

artículo científico publicado en 2003

The temporal and spatial expression pattern of the LGI1 epilepsy predisposition gene during mouse embryonic cranial development

artículo científico publicado en 2011

The use of SCID mice for the growth of retinoblastoma cell lines and for the establishment of xenografts from primary tumours

artículo científico publicado en 1997

Ubiquitin-conjugating enzyme UBE2C: molecular biology, role in tumorigenesis, and potential as a biomarker.

artículo científico publicado en 2011

WAVE3 promotes cell motility and invasion through the regulation of MMP-1, MMP-3, and MMP-9 expression

artículo científico publicado en 2005

WAVE3-mediated cell migration and lamellipodia formation are regulated downstream of phosphatidylinositol 3-kinase

artículo científico publicado en 2005

ZNF198 protein, involved in rearrangement in myeloproliferative disease, forms complexes with the DNA repair-associated HHR6A/6B and RAD18 proteins

artículo científico publicado en 2003

Lista de obras de John K. Cowell

A Yeast Artificial Chromosome Contig That Spans the RB1-D13S31 Interval on Human Chromosome 13 and Encompasses the Frequently Deleted Region in B-cell Chronic Lymphocytic Leukemia

A novel member of the WD-repeat gene family, WDR11, maps to the 10q26 region and is disrupted by a chromosome translocation in human glioblastoma cells.

A role for p300/CREB binding protein genes in promoting cancer progression in colon cancer cell lines with microsatellite instability

Aberrant expression of the tumour suppressor gene p53 is very frequent in Wilms' tumours

Acute progression of BCR-FGFR1 induced murine B-lympho/myeloproliferative disorder suggests involvement of lineages at the pro-B cell stage.

Analysis of the RB1 gene in children with retinoblastoma having residential connections to West Cumbria, England

Analysis of wilms tumors using SNP mapping array-based comparative genomic hybridization.

Application of bacterial artificial chromosome array-based comparative genomic hybridization and spectral karyotyping to the analysis of glioblastoma multiforme

Application of oligonucleotides arrays for coincident comparative genomic hybridization, ploidy status and loss of heterozygosity studies in human cancers.

Application of spectral karyotyping to the analysis of the human chromosome complement of interspecies somatic cell hybrids

Array CGH analysis of pediatric medulloblastomas

Array comparative genome hybridization analysis of acute lymphoblastic leukaemia and acute megakaryoblastic leukaemia in patients with Down syndrome

Assignment of four sequence-tagged sites to three subregions of 13q12 using a somatic cell hybrid mapping panel

CLCA2 tumour suppressor gene in 1p31 is epigenetically regulated in breast cancer

Candidate glioblastoma development gene identification using concordance between copy number abnormalities and gene expression level changes.

Characterization of FAM10A4, a member of the ST13 tumor suppressor gene family that maps to the 13q14.3 region associated with B-Cell leukemia, multiple myeloma, and prostate cancer

Characterization of the breakpoints in a t(8;13)(p11;q12) translocation from a patient with myeloproliferative disease using fluorescence in situ hybridization

Chromosome analysis of human neuroblastoma cell line TR14 showing double minutes and an aberration involving chromosome 1.

Colon carcinoma cells harboring PIK3CA mutations display resistance to growth factor deprivation induced apoptosis.

Comprehensive analysis of loss of heterozygosity events in glioblastoma using the 100K SNP mapping arrays and comparison with copy number abnormalities defined by BAC array comparative genomic hybridization.

Constitutional nonsense germline mutations in the RB1 gene detected in patients with early onset unilateral retinoblastoma

Constitutive Notch pathway activation in murine ZMYM2-FGFR1–induced T-cell lymphomas associated with atypical myeloproliferative disease ⬇️

Copy number and gene expression alterations in radiation-induced papillary thyroid carcinoma from chernobyl pediatric patients.

Critical individual roles of the BCR and FGFR1 kinase domains in BCR-FGFR1-driven stem cell leukemia/lymphoma syndrome

DNA methyltransferase 1-mediated CpG methylation of the miR-150-5p promoter contributes to fibroblast growth factor receptor 1-driven leukemogenesis

Differential expression of the LGI and SLIT families of genes in human cancer cells

Direct isolation of human transcribed sequences from yeast artificial chromosomes through the application of RNA fingerprinting

Distinct molecular signatures in pediatric infratentorial glioblastomas defined by aCGH.

EagI and NotI linking clones from human chromosomes 11 and Xp.

Editorial

Epilepsy research gets new guidance

Evolution of a normal karyotype in a mouse bladder epithelial cell line transformed in vitro

Functional interrelationship between the WASF3 and KISS1 metastasis-associated genes in breast cancer cells.

Gain of 1q is a potential univariate negative prognostic marker for survival in medulloblastoma

Genetic analysis of Down syndrome-associated heart defects in mice.

Genetic fingerprinting of the development and progression of T-cell lymphoma in a murine model of atypical myeloproliferative disorder initiated by the ZNF198-fibroblast growth factor receptor-1 chimeric tyrosine kinase.

Genome wide copy number abnormalities in pediatric medulloblastomas as assessed by array comparative genome hybridization

Genome-wide aberrations in pancreatic adenocarcinoma.

Genomic analysis of CD8+ NK/T cell line, 'SRIK-NKL', with array-based CGH (aCGH), SKY/FISH and molecular mapping

Genomic profiling of myeloid sarcoma by array comparative genomic hybridization

Germline mutations in the RB1 gene in patients with hereditary retinoblastoma

HIF1A induces expression of the WASF3 metastasis-associated gene under hypoxic conditions.

HSP90 and HSP70 Proteins Are Essential for Stabilization and Activation of WASF3 Metastasis-promoting Protein ⬇️

HSPA1A is an important regulator of the stability and function of ZNF198 and its oncogenic derivative, ZNF198-FGFR1.

Homozygous inactivation of the LGI1 gene results in hypomyelination in the peripheral and central nervous systems.

Identification and characterisation of constitutional chromosome abnormalities using arrays of bacterial artificial chromosomes.

Identification of YAC clones for human chromosome 1p32 and physical mapping of the infantile neuronal ceroid lipofuscinosis (INCL) locus

Identification of consistent novel submegabase deletions in low-grade oligodendrogliomas using array-based comparative genomic hybridization

Incorporation of 35 novel gene transcripts into the physical and genetic map of human chromosome 13

Induction of the plasminogen activator inhibitor-2 in cells expressing the ZNF198/FGFR1 fusion kinase that is involved in atypical myeloproliferative disease.

Insulin-like growth factor-II gene expression in Wilms' tumour and embryonic tissues

Integration of the physical and genetic linkage map for human chromosome 13

Investigation of LGI1 as the antigen in limbic encephalitis previously attributed to potassium channels: a case series

Knockdown of zebrafish Lgi1a results in abnormal development, brain defects and a seizure-like behavioral phenotype

LGI1, a putative tumor metastasis suppressor gene, controls in vitro invasiveness and expression of matrix metalloproteinases in glioma cells through the ERK1/2 pathway

Lgi1 null mutant mice exhibit myoclonic seizures and CA1 neuronal hyperexcitability

Localization of the 8;13 translocation breakpoint associated with myeloproliferative disease to a 1.5 mbp region of chromosome 13

Long tandem repeats as a form of genomic copy number variation: structure and length polymorphism of a chromosome 5p repeat in control and schizophrenia populations

Loss of zebrafish lgi1b leads to hydrocephalus and sensitization to pentylenetetrazol induced seizure-like behavior

Manipulation of nonsense mediated decay identifies gene mutations in colon cancer Cells with microsatellite instability

Mass spectrometry identifies LGI1-interacting proteins that are involved in synaptic vesicle function in the human brain

Mass spectroscopy identifies the splicing-associated proteins, PSF, hnRNP H3, hnRNP A2/B1, and TLS/FUS as interacting partners of the ZNF198 protein associated with rearrangement in myeloproliferative disease

Molecular characterization of a (1;10)(p22;q21) constitutional translocation from a patient with neuroblastoma

Molecular characterization of a 7p15-21 homozygous deletion in a Wilms tumor

Molecular characterization of the 1p22 breakpoint region spanning the constitutional translocation breakpoint in a neuroblastoma patient with a t(1;10)(p22;q21)

Molecular characterization of the breakpoint region associated with a constitutional t(2;15)(q34;q26) in a patient with multiple myeloma

Molecular definition of chromosome translocations involving 10q24 and 19q13 in human malignant glioma cells

Molecular study of malignant gliomas treated with epidermal growth factor receptor inhibitors: tissue analysis from North American Brain Tumor Consortium Trials 01-03 and 00-01.

Mutation in the FGFR1 tyrosine kinase domain or inactivation of PTEN is associated with acquired resistance to FGFR inhibitors in FGFR1-driven leukemia/lymphomas.

NB4S, a member of the TBC1 domain family of genes, is truncated as a result of a constitutional t(1;10)(p22;q21) chromosome translocation in a patient with stage 4S neuroblastoma

Novel amplicons on the short arm of chromosome 7 identified using high resolution array CGH contain over expressed genes in addition to EGFR in glioblastoma multiforme

Obtaining DNA from a geographically dispersed cohort of current and former smokers: use of mail-based mouthwash collection and monetary incentives.

Oncogenic point mutations in exon 20 of the RB1 gene in families showing incomplete penetrance and mild expression of the retinoblastoma phenotype

Overlay analysis of the oligonucleotide array gene expression profiles and copy number abnormalities as determined by array comparative genomic hybridization in medulloblastomas

Pediatric primary intramedullary spinal cord glioblastoma

Phosphorylation of the SSBP2 and ABL proteins by the ZNF198-FGFR1 fusion kinase seen in atypical myeloproliferative disorders as revealed by phosphopeptide-specific MS.

Ploidy status and copy number aberrations in primary glioblastomas defined by integrated analysis of allelic ratios, signal ratios and loss of heterozygosity using 500K SNP Mapping Arrays

Ponatinib suppresses the development of myeloid and lymphoid malignancies associated with FGFR1 abnormalities

Prenatal exclusion of hereditary retinoblastoma