Lista de obras - Trine Meldgaard Lund - Dominio Público Uruguay

A Model-Based Approach for Joint Analysis of Pain Intensity and Opioid Consumption in Postoperative Pain

artículo científico publicado en 2016

A Pharmacokinetic-Pharmacodynamic Model of Morphine Exposure and Subsequent Morphine Consumption in Postoperative Pain

artículo científico publicado en 2016

A review of morphine and morphine-6-glucuronide's pharmacokinetic-pharmacodynamic relationships in experimental and clinical pain

artículo científico

Analysis of opioid consumption in clinical trials: a simulation based analysis of power of four approaches.

artículo científico publicado en 2017

Astrocyte glycogen metabolism is required for neural activity during aglycemia or intense stimulation in mouse white matter.

artículo científico publicado en 2005

Availability of neurotransmitter glutamate is diminished when beta-hydroxybutyrate replaces glucose in cultured neurons.

artículo científico publicado en 2009

Body of evidence and approaches applied in the clinical development programme of fixed-dose combinations in the European Union from 2010 to 2016

artículo científico publicado en 2019

Changes in brain levels of N-acylethanolamines and 2-arachidonoylglycerol in focal cerebral ischemia in mice

Co-administration of morphine and gabapentin leads to dose dependent synergistic effects in a rat model of postoperative pain

artículo científico publicado en 2015

Demonstrating Contribution of Components of Fixed-Dose Drug Combinations Through Longitudinal Exposure-Response Analysis

artículo científico publicado en 2020

Dose Finding in the Clinical Development of 60 US Food and Drug Administration-Approved Drugs Compared With Learning vs. Confirming Recommendations

artículo científico publicado en 2019

Effects of taurine depletion on cell migration and NCAM expression in cultures of dissociated mouse cerebellum and N2A cells.

artículo científico publicado en 1998

Feasibility of Exposure-Response Analyses for Clinical Dose-Ranging Studies of Drug Combinations

artículo científico publicado en 2018

High-dose naloxone, an experimental tool uncovering latent sensitisation: pharmacokinetics in humans

scientific article published on 18 January 2019

High-dose naloxone: Effects by late administration on pain and hyperalgesia following a human heat injury model. A randomized, double-blind, placebo-controlled, crossover trial with an enriched enrollment design

artículo científico publicado en 2020

Hydroxylated analogues of 5-aminovaleric acid as 4-aminobutyric acidB receptor antagonists: stereostructure-activity relationships

artículo científico publicado el 1 de marzo de 1992

Impact of dose-escalation schemes and drug discontinuation on weight loss outcomes with liraglutide 3.0 mg: A model-based approach

artículo científico publicado en 2020

Integrated Item Response Theory Modeling of Multiple Patient-Reported Outcomes Assessing Lower Urinary Tract Symptoms Associated with Benign Prostatic Hyperplasia

artículo científico publicado en 2020

K(ATP) channel openers in the trigeminovascular system

artículo científico publicado en 2011

Localization and pharmacological characterization of voltage dependent calcium channels in cultured neocortical neurons.

artículo científico publicado en 2001

Modelling concentration–analgesia relationships for morphine to evaluate experimental pain models

article by Eva Sverrisdóttir et al published 23 January 2015 in European Journal of Pharmaceutical Sciences

Molecular pharmacology of the AMPA agonist, (S)-2-amino-3-(3-hydroxy-5-phenyl-4-isoxazolyl)propionic acid [(S)-APPA] and the AMPA antagonist, (R)-APPA.

artículo científico publicado en 1994

Optimizing Dose-Finding Studies for Drug Combinations Based on Exposure-Response Models

artículo científico publicado en 2019

Population Pharmacokinetic Modelling of Morphine, Gabapentin and their Combination in the Rat.

artículo científico publicado en 2016

Quantification of the Pharmacodynamic Interaction of Morphine and Gabapentin Using a Response Surface Approach

artículo científico publicado en 2017

Repeated Time-to-event Analysis of Consecutive Analgesic Events in Postoperative Pain

artículo científico publicado en 2015

Role of GluR2 expression in AMPA-induced toxicity in cultured murine cerebral cortical neurons

artículo científico publicado en 2001

Simultaneous quantification of high-dose naloxone and naloxone-3-β-d-glucuronide in human plasma by UHPLC-MS/MS

scientific article published on 21 January 2019

The metabolic impact of β-hydroxybutyrate on neurotransmission: Reduced glycolysis mediates changes in calcium responses and KATP channel receptor sensitivity.

artículo científico publicado en 2015

β-Hydroxybutyrate is the preferred substrate for GABA and glutamate synthesis while glucose is indispensable during depolarization in cultured GABAergic neurons

artículo científico publicado en 2011

Lista de obras de Trine Meldgaard Lund

A Model-Based Approach for Joint Analysis of Pain Intensity and Opioid Consumption in Postoperative Pain

A Pharmacokinetic-Pharmacodynamic Model of Morphine Exposure and Subsequent Morphine Consumption in Postoperative Pain

A review of morphine and morphine-6-glucuronide's pharmacokinetic-pharmacodynamic relationships in experimental and clinical pain

Analysis of opioid consumption in clinical trials: a simulation based analysis of power of four approaches.

Astrocyte glycogen metabolism is required for neural activity during aglycemia or intense stimulation in mouse white matter.

Availability of neurotransmitter glutamate is diminished when beta-hydroxybutyrate replaces glucose in cultured neurons.

Body of evidence and approaches applied in the clinical development programme of fixed-dose combinations in the European Union from 2010 to 2016

Changes in brain levels of N-acylethanolamines and 2-arachidonoylglycerol in focal cerebral ischemia in mice

Co-administration of morphine and gabapentin leads to dose dependent synergistic effects in a rat model of postoperative pain

Demonstrating Contribution of Components of Fixed-Dose Drug Combinations Through Longitudinal Exposure-Response Analysis

Dose Finding in the Clinical Development of 60 US Food and Drug Administration-Approved Drugs Compared With Learning vs. Confirming Recommendations

Effects of taurine depletion on cell migration and NCAM expression in cultures of dissociated mouse cerebellum and N2A cells.

Feasibility of Exposure-Response Analyses for Clinical Dose-Ranging Studies of Drug Combinations

High-dose naloxone, an experimental tool uncovering latent sensitisation: pharmacokinetics in humans

High-dose naloxone: Effects by late administration on pain and hyperalgesia following a human heat injury model. A randomized, double-blind, placebo-controlled, crossover trial with an enriched enrollment design

Hydroxylated analogues of 5-aminovaleric acid as 4-aminobutyric acidB receptor antagonists: stereostructure-activity relationships

Impact of dose-escalation schemes and drug discontinuation on weight loss outcomes with liraglutide 3.0 mg: A model-based approach

Integrated Item Response Theory Modeling of Multiple Patient-Reported Outcomes Assessing Lower Urinary Tract Symptoms Associated with Benign Prostatic Hyperplasia

K(ATP) channel openers in the trigeminovascular system

Localization and pharmacological characterization of voltage dependent calcium channels in cultured neocortical neurons.

Modelling concentration–analgesia relationships for morphine to evaluate experimental pain models

Molecular pharmacology of the AMPA agonist, (S)-2-amino-3-(3-hydroxy-5-phenyl-4-isoxazolyl)propionic acid [(S)-APPA] and the AMPA antagonist, (R)-APPA.

Optimizing Dose-Finding Studies for Drug Combinations Based on Exposure-Response Models

Population Pharmacokinetic Modelling of Morphine, Gabapentin and their Combination in the Rat.

Quantification of the Pharmacodynamic Interaction of Morphine and Gabapentin Using a Response Surface Approach

Repeated Time-to-event Analysis of Consecutive Analgesic Events in Postoperative Pain

Role of GluR2 expression in AMPA-induced toxicity in cultured murine cerebral cortical neurons

Simultaneous quantification of high-dose naloxone and naloxone-3-β-d-glucuronide in human plasma by UHPLC-MS/MS

The metabolic impact of β-hydroxybutyrate on neurotransmission: Reduced glycolysis mediates changes in calcium responses and KATP channel receptor sensitivity.

β-Hydroxybutyrate is the preferred substrate for GABA and glutamate synthesis while glucose is indispensable during depolarization in cultured GABAergic neurons