Lista de obras - Jens Schittenhelm - Dominio Público Uruguay

47-year-old woman with a clival mass.

artículo científico publicado en 2008

A novel mutation in LRSAM1 causes axonal Charcot-Marie-Tooth disease with dominant inheritance

artículo científico publicado en 2014

AKT1E17K mutations cluster with meningothelial and transitional meningiomas and can be detected by SFRP1 immunohistochemistry

artículo científico publicado en 2013

ATRX and IDH1-R132H immunohistochemistry with subsequent copy number analysis and IDH sequencing as a basis for an "integrated" diagnostic approach for adult astrocytoma, oligodendroglioma and glioblastoma

artículo científico publicado en 2014

ATRX immunostaining predicts IDH and H3F3A status in gliomas

artículo científico publicado en 2016

Activated leukocyte cell adhesion molecule is expressed in neuroepithelial neoplasms and decreases with tumor malignancy, matrix metalloproteinase 2 expression, and absence of IDH1R132H mutation

artículo científico publicado en 2012

Adult IDH wild type astrocytomas biologically and clinically resolve into other tumor entities

artículo científico publicado en 2015

Analysis of IDH1-R132 mutation, BRAF V600 mutation and KIAA1549-BRAF fusion transcript status in central nervous system tumors supports pediatric tumor classification

artículo científico publicado en 2015

Anaplastic astrocytoma with piloid features, a novel molecular class of IDH wildtype glioma with recurrent MAPK pathway, CDKN2A/B and ATRX alterations.

artículo científico publicado en 2018

Application of mutant IDH1 antibody to differentiate diffuse glioma from nonneoplastic central nervous system lesions and therapy-induced changes

artículo científico publicado en 2010

Association of dynamic susceptibility magnetic resonance imaging at initial tumor diagnosis with the prognosis of different molecular glioma subtypes

artículo científico publicado en 2020

BRAF-mutated pleomorphic xanthoastrocytoma is associated with temporal location, reticulin fiber deposition and CD34 expression.

artículo científico publicado en 2014

Brain invasion in otherwise benign meningiomas does not predict tumor recurrence

artículo científico publicado en 2016

CASP9 germline mutation in a family with multiple brain tumors

artículo científico publicado en 2016

CD133 expression is associated with small round blue cell tumour morphology in human central nervous system neoplasms

artículo científico publicado en 2011

CD8(+)/perforin/granzyme B(+) effector cells infiltrating cerebellum and inferior olives in gluten ataxia

artículo científico publicado en 2009

CNS Invasion in Meningioma-How the Intraoperative Assessment Can Improve the Prognostic Evaluation of Tumor Recurrence

artículo científico publicado en 2020

Choroid plexus tumors differ from metastatic carcinomas by expression of the excitatory amino acid transporter-1.

artículo científico publicado en 2006

Comparative analysis of annexin-1 in neuroepithelial tumors shows altered expression with the grade of malignancy but is not associated with survival

artículo científico publicado en 2009

Comparing the expression of integrins αvβ3, αvβ5, αvβ6, αvβ8, fibronectin and fibrinogen in human brain metastases and their corresponding primary tumors

artículo científico publicado en 2013

Comparison of three different MR perfusion techniques and MR spectroscopy for multiparametric assessment in distinguishing recurrent high-grade gliomas from stable disease

artículo científico publicado en 2013

Confirmation of R132H mutation of isocitrate dehydrogenase 1 as an independent prognostic factor in anaplastic astrocytoma

artículo científico publicado en 2011

Contrast enhancement predicting survival in integrated molecular subtypes of diffuse glioma: an observational cohort study.

artículo científico publicado en 2018

Correlative assessment of tumor microcirculation using contrast-enhanced perfusion MRI and intravoxel incoherent motion diffusion-weighted MRI: is there a link between them?

artículo científico publicado en 2014

Cutting Edge: A2B Adenosine receptor signaling provides potent protection during intestinal ischemia/reperfusion injury

artículo científico publicado en 2009

DNA methylation-based classification and grading system for meningioma: a multicentre, retrospective analysis

artículo científico publicado en 2017

DNA methylation-based classification of central nervous system tumours.

artículo científico publicado en 2018

Diagnostic value of EAAT-1 and Kir7.1 for distinguishing endolymphatic sac tumors from choroid plexus tumors

artículo científico publicado en 2012

Differential expression of the tumor suppressor A-kinase anchor protein 12 in human diffuse and pilocytic astrocytomas is regulated by promoter methylation

artículo científico publicado en 2013

Diffuse glioneuronal tumour with oligodendroglioma-like features and nuclear clusters (DGONC) - a molecularly defined glioneuronal CNS tumour class displaying recurrent monosomy 14

artículo científico publicado en 2019

Distribution of TERT promoter mutations in pediatric and adult tumors of the nervous system

artículo científico publicado en 2013

Effect of Perfusion on Diffusion Kurtosis Imaging Estimates for In Vivo Assessment of Integrated 2016 WHO Glioma Grades : A Cross-Sectional Observational Study

artículo científico publicado en 2017

Endothelial cell-derived angiopoietin-2 is a therapeutic target in treatment-naive and bevacizumab-resistant glioblastoma

artículo científico publicado en 2015

Erratum to: In vivo molecular profiling of human glioma using diffusion kurtosis imaging

artículo científico publicado en 2016

Evidence of ubiquitous in vivo and in vitro expression of pro-apoptotic Smac/DIABLO protein in meningioma cell lines.

artículo científico publicado en 2009

Expression of EAAT-1 distinguishes choroid plexus tumors from normal and reactive choroid plexus epithelium

artículo científico publicado en 2009

Extra-adrenal paravertebral myelolipoma mimicking a thoracic schwannoma

artículo científico publicado en 2009

Extracellular adenosine production by ecto-5'-nucleotidase protects during murine hepatic ischemic preconditioning

artículo científico publicado en 2008

FGFR3 overexpression is a useful detection tool for FGFR3 fusions and sequence variations in glioma

artículo científico publicado en 2020

Farewell to oligoastrocytoma: in situ molecular genetics favor classification as either oligodendroglioma or astrocytoma

artículo científico publicado en 2014

Glioma Grading and Determination of IDH Mutation Status and ATRX loss by DCE and ASL Perfusion

artículo científico publicado en 2017

Glioma grading by dynamic susceptibility contrast perfusion and 11C-methionine positron emission tomography using different regions of interest

artículo científico publicado en 2018

Gliosarcoma with chondroid and osseous differentiation

artículo científico publicado en 2007

High Expression of Somatostatin Receptors 2A, 3, and 5 in Corticotroph Pituitary Adenoma

artículo científico publicado en 2018

Histogram analysis of diffusion kurtosis imaging estimates for in vivo assessment of 2016 WHO glioma grades: A cross-sectional observational study

artículo científico publicado en 2017

Histologically distinct neuroepithelial tumors with histone 3 G34 mutation are molecularly similar and comprise a single nosologic entity

artículo científico publicado en 2015

Holocord pilocytic astrocytoma--case report and review of the literature

artículo científico publicado en 2008

Hypoxia-Inducible Factor-1α–Dependent Protection from Intestinal Ischemia/Reperfusion Injury Involves Ecto-5′-Nucleotidase (CD73) and the A2B Adenosine Receptor ⬇️

artículo científico publicado el 28 de febrero de 2011

IDH1 R132H mutation in a pilocytic astrocytoma: a case report

artículo científico publicado en 2015

Immunohistochemical comparative analysis of GFAP, MAP - 2, NOGO - A, OLIG - 2 and WT - 1 expression in WHO 2016 classified neuroepithelial tumours and their prognostic value

artículo científico publicado en 2017

Implications of Vestibular Schwannoma Consistency: Analysis of 140 Cases Regarding Radiologic and Clinical Features

artículo científico publicado en 2016

In Vivo Molecular Profiling of Human Glioma : Cross-Sectional Observational Study Using Dynamic Susceptibility Contrast Magnetic Resonance Perfusion Imaging.

artículo científico publicado en 2018

In vivo molecular profiling of human glioma using diffusion kurtosis imaging

artículo científico publicado en 2016

Infant high grade gliomas comprise multiple subgroups characterized by novel targetable gene fusions and favorable outcomes

scientific article published on 01 April 2020

Inflammatory myofibroblastic tumor of the ulnar nerve. Case report and review of the literature

artículo científico publicado en 2007

Intravoxel incoherent motion diffusion-weighted MR imaging of gliomas: feasibility of the method and initial results

artículo científico publicado en 2013

Longitudinal expression analysis of αv integrins in human gliomas reveals upregulation of integrin αvβ3 as a negative prognostic factor

artículo científico

Low FoxG1 and high Olig-2 labelling indices define a prognostically favourable subset in isocitrate dehydrogenase (IDH)-mutant gliomas.

artículo científico publicado en 2017

Low grade ganglioglioma rapidly progressing to a WHO grade IV tumor showing malignant transformation in both astroglial and neuronal cell components.

artículo científico publicado en 2007

MR spectroscopy for in vivo assessment of the oncometabolite 2-hydroxyglutarate and its effects on cellular metabolism in human brain gliomas at 9.4T.

artículo científico publicado en 2016

Management of holocord pilocytic astrocytomas in children and adolescents: an update

artículo científico publicado en 2012

Mature cerebellar teratoma in adulthood

artículo científico publicado en 2008

Meningeal hemangiopericytoma and solitary fibrous tumors carry the NAB2-STAT6 fusion and can be diagnosed by nuclear expression of STAT6 protein

artículo científico publicado en 2013

Methylation-based classification of benign and malignant peripheral nerve sheath tumors

artículo científico publicado en 2016

Multiple thromboembolic events in fetofetal transfusion syndrome in triplets contributing to the understanding of pathogenesis of hydranencephaly in combination with polymicrogyria

artículo científico publicado en 2006

Mutant BRAF V600E protein in ganglioglioma is predominantly expressed by neuronal tumor cells

artículo científico publicado en 2013

Mutation-specific IDH1 antibody differentiates oligodendrogliomas and oligoastrocytomas from other brain tumors with oligodendroglioma-like morphology.

artículo científico publicado en 2010

Neurofibromin specific antibody differentiates malignant peripheral nerve sheath tumors (MPNST) from other spindle cell neoplasms

artículo científico publicado en 2014

New Brain Tumor Entities Emerge from Molecular Classification of CNS-PNETs

artículo científico publicado en 2016

Oncogenic KRAS hotspot mutations are rare in IDH-mutant gliomas

scientific article published on 01 February 2019

Osteonectin expression in surrounding stroma of craniopharyngiomas: association with recurrence rate and brain infiltration

artículo científico publicado en 2013

Paired box gene 8 (PAX8) expression is associated with sonic hedgehog (SHH)/wingless int (WNT) subtypes, desmoplastic histology and patient survival in human medulloblastomas

artículo científico publicado en 2015

Parenchymal accumulation of CD163+ macrophages/microglia in multiple sclerosis brains

artículo científico publicado en 2011

Pitfalls in the assessment of MGMT expression and in its correlation with survival in diffuse astrocytomas: proposal of a feasible immunohistochemical approach.

artículo científico publicado en 2007

Pituitary adenomas and craniopharyngiomas are CDX2 negative neoplasms

artículo científico publicado en 2010

Prognostic relevance of global histone 3 lysine 9 acetylation in ependymal tumors

artículo científico publicado en 2013

Prognostic value of blood flow estimated by arterial spin labeling and dynamic susceptibility contrast-enhanced MR imaging in high-grade gliomas

artículo científico publicado en 2014

Prognostic value of blood flow measurements using arterial spin labeling in gliomas

artículo científico publicado en 2014

Radiation-induced gliomas represent H3-/IDH-wild type pediatric gliomas with recurrent PDGFRA amplification and loss of CDKN2A/B

artículo científico publicado en 2021

Rathke's cleft cyst rupture as potential initial event of a secondary perifocal lymphocytic hypophysitis: proposal of an unusual pathogenetic event and review of the literature

artículo científico publicado en 2008

Recent advances in subtyping tumors of the central nervous system using molecular data

artículo científico publicado en 2016

Retraction: Hypoxia-Inducible Factor-1α-Dependent Protection from Intestinal Ischemia/Reperfusion Injury Involves Ecto-5'-Nucleotidase (CD73) and the A2B Adenosine Receptor

artículo científico publicado en 2017

SP1-dependent induction of CD39 facilitates hepatic ischemic preconditioning

artículo científico publicado en 2010

Sarcoma classification by DNA methylation profiling

artículo científico publicado en 2021

Severe hypoxia and multiple infarctions resembling Creutzfeldt-Jakob disease.

artículo científico publicado en 2008

Spinal metastasis of endometrial stromal sarcoma: clinicopathological features and management

artículo científico publicado en 2010

T1ρ-based dynamic glucose-enhanced (DGEρ) MRI at 3 T: method development and early clinical experience in the human brain

scientific article published on 23 June 2019

TERT Promoter Mutations and Risk of Recurrence in Meningioma

artículo científico publicado en 2015

The "go or grow" potential of gliomas is linked to the neuropeptide processing enzyme carboxypeptidase E and mediated by metabolic stress

artículo científico publicado en 2012

The Cellular Retinoic Acid Binding Protein 2 Promotes Survival of Malignant Peripheral Nerve Sheath Tumor Cells

artículo científico publicado en 2017

The embryonic stem cell factor UTF1 serves as a reliable diagnostic marker for germinomas

artículo científico publicado en 2014

The role of Simpson grading in meningiomas after integration of the updated WHO classification and adjuvant radiotherapy

artículo científico publicado en 2020

The role of integrins in primary and secondary brain tumors

artículo científico publicado en 2016

Tissue microarrays - translational biomarker research in the fast lane

scientific article published on 13 September 2018

Tryptophan is a marker of human postmortem brain tissue quality.

artículo científico publicado en 2009

Tumor Vessel Normalization, Immunostimulatory Reprogramming, and Improved Survival in Glioblastoma with Combined Inhibition of PD-1, Angiopoietin-2, and VEGF

artículo científico publicado en 2019

Tumour necrosis factor receptor superfamily member 9 (TNFRSF9) is up-regulated in reactive astrocytes in human gliomas

artículo científico publicado en 2015

Unusual presentation of central nervous system metastases: mechanisms of spread and radiological findings

artículo científico publicado en 2008

Use of a hanging-weight system for liver ischemic preconditioning in mice

artículo científico publicado en 2008

VE1 immunohistochemistry in pituitary adenomas is not associated with BRAF V600E mutation

artículo científico publicado en 2013

WT1 expression distinguishes astrocytic tumor cells from normal and reactive astrocytes.

artículo científico publicado en 2008

WT1 expression increases with malignancy and indicates unfavourable outcome in astrocytoma.

artículo científico

Lista de obras de Jens Schittenhelm

47-year-old woman with a clival mass.

A novel mutation in LRSAM1 causes axonal Charcot-Marie-Tooth disease with dominant inheritance

AKT1E17K mutations cluster with meningothelial and transitional meningiomas and can be detected by SFRP1 immunohistochemistry

ATRX and IDH1-R132H immunohistochemistry with subsequent copy number analysis and IDH sequencing as a basis for an "integrated" diagnostic approach for adult astrocytoma, oligodendroglioma and glioblastoma

ATRX immunostaining predicts IDH and H3F3A status in gliomas

Activated leukocyte cell adhesion molecule is expressed in neuroepithelial neoplasms and decreases with tumor malignancy, matrix metalloproteinase 2 expression, and absence of IDH1R132H mutation

Adult IDH wild type astrocytomas biologically and clinically resolve into other tumor entities

Analysis of IDH1-R132 mutation, BRAF V600 mutation and KIAA1549-BRAF fusion transcript status in central nervous system tumors supports pediatric tumor classification

Anaplastic astrocytoma with piloid features, a novel molecular class of IDH wildtype glioma with recurrent MAPK pathway, CDKN2A/B and ATRX alterations.

Application of mutant IDH1 antibody to differentiate diffuse glioma from nonneoplastic central nervous system lesions and therapy-induced changes

Association of dynamic susceptibility magnetic resonance imaging at initial tumor diagnosis with the prognosis of different molecular glioma subtypes

BRAF-mutated pleomorphic xanthoastrocytoma is associated with temporal location, reticulin fiber deposition and CD34 expression.

Brain invasion in otherwise benign meningiomas does not predict tumor recurrence

CASP9 germline mutation in a family with multiple brain tumors

CD133 expression is associated with small round blue cell tumour morphology in human central nervous system neoplasms

CD8(+)/perforin/granzyme B(+) effector cells infiltrating cerebellum and inferior olives in gluten ataxia

CNS Invasion in Meningioma-How the Intraoperative Assessment Can Improve the Prognostic Evaluation of Tumor Recurrence

Choroid plexus tumors differ from metastatic carcinomas by expression of the excitatory amino acid transporter-1.

Comparative analysis of annexin-1 in neuroepithelial tumors shows altered expression with the grade of malignancy but is not associated with survival

Comparing the expression of integrins αvβ3, αvβ5, αvβ6, αvβ8, fibronectin and fibrinogen in human brain metastases and their corresponding primary tumors

Comparison of three different MR perfusion techniques and MR spectroscopy for multiparametric assessment in distinguishing recurrent high-grade gliomas from stable disease

Confirmation of R132H mutation of isocitrate dehydrogenase 1 as an independent prognostic factor in anaplastic astrocytoma

Contrast enhancement predicting survival in integrated molecular subtypes of diffuse glioma: an observational cohort study.

Correlative assessment of tumor microcirculation using contrast-enhanced perfusion MRI and intravoxel incoherent motion diffusion-weighted MRI: is there a link between them?

Cutting Edge: A2B Adenosine receptor signaling provides potent protection during intestinal ischemia/reperfusion injury

DNA methylation-based classification and grading system for meningioma: a multicentre, retrospective analysis

DNA methylation-based classification of central nervous system tumours.

Diagnostic value of EAAT-1 and Kir7.1 for distinguishing endolymphatic sac tumors from choroid plexus tumors

Differential expression of the tumor suppressor A-kinase anchor protein 12 in human diffuse and pilocytic astrocytomas is regulated by promoter methylation

Diffuse glioneuronal tumour with oligodendroglioma-like features and nuclear clusters (DGONC) - a molecularly defined glioneuronal CNS tumour class displaying recurrent monosomy 14

Distribution of TERT promoter mutations in pediatric and adult tumors of the nervous system

Effect of Perfusion on Diffusion Kurtosis Imaging Estimates for In Vivo Assessment of Integrated 2016 WHO Glioma Grades : A Cross-Sectional Observational Study

Endothelial cell-derived angiopoietin-2 is a therapeutic target in treatment-naive and bevacizumab-resistant glioblastoma

Erratum to: In vivo molecular profiling of human glioma using diffusion kurtosis imaging

Evidence of ubiquitous in vivo and in vitro expression of pro-apoptotic Smac/DIABLO protein in meningioma cell lines.

Expression of EAAT-1 distinguishes choroid plexus tumors from normal and reactive choroid plexus epithelium

Extra-adrenal paravertebral myelolipoma mimicking a thoracic schwannoma

Extracellular adenosine production by ecto-5'-nucleotidase protects during murine hepatic ischemic preconditioning

FGFR3 overexpression is a useful detection tool for FGFR3 fusions and sequence variations in glioma

Farewell to oligoastrocytoma: in situ molecular genetics favor classification as either oligodendroglioma or astrocytoma

Glioma Grading and Determination of IDH Mutation Status and ATRX loss by DCE and ASL Perfusion

Glioma grading by dynamic susceptibility contrast perfusion and 11C-methionine positron emission tomography using different regions of interest

Gliosarcoma with chondroid and osseous differentiation

High Expression of Somatostatin Receptors 2A, 3, and 5 in Corticotroph Pituitary Adenoma

Histogram analysis of diffusion kurtosis imaging estimates for in vivo assessment of 2016 WHO glioma grades: A cross-sectional observational study

Histologically distinct neuroepithelial tumors with histone 3 G34 mutation are molecularly similar and comprise a single nosologic entity

Holocord pilocytic astrocytoma--case report and review of the literature

Hypoxia-Inducible Factor-1α–Dependent Protection from Intestinal Ischemia/Reperfusion Injury Involves Ecto-5′-Nucleotidase (CD73) and the A2B Adenosine Receptor ⬇️

IDH1 R132H mutation in a pilocytic astrocytoma: a case report

Immunohistochemical comparative analysis of GFAP, MAP - 2, NOGO - A, OLIG - 2 and WT - 1 expression in WHO 2016 classified neuroepithelial tumours and their prognostic value

Implications of Vestibular Schwannoma Consistency: Analysis of 140 Cases Regarding Radiologic and Clinical Features

In Vivo Molecular Profiling of Human Glioma : Cross-Sectional Observational Study Using Dynamic Susceptibility Contrast Magnetic Resonance Perfusion Imaging.

In vivo molecular profiling of human glioma using diffusion kurtosis imaging

Infant high grade gliomas comprise multiple subgroups characterized by novel targetable gene fusions and favorable outcomes

Inflammatory myofibroblastic tumor of the ulnar nerve. Case report and review of the literature

Intravoxel incoherent motion diffusion-weighted MR imaging of gliomas: feasibility of the method and initial results

Longitudinal expression analysis of αv integrins in human gliomas reveals upregulation of integrin αvβ3 as a negative prognostic factor

Low FoxG1 and high Olig-2 labelling indices define a prognostically favourable subset in isocitrate dehydrogenase (IDH)-mutant gliomas.

Low grade ganglioglioma rapidly progressing to a WHO grade IV tumor showing malignant transformation in both astroglial and neuronal cell components.

MR spectroscopy for in vivo assessment of the oncometabolite 2-hydroxyglutarate and its effects on cellular metabolism in human brain gliomas at 9.4T.

Management of holocord pilocytic astrocytomas in children and adolescents: an update

Mature cerebellar teratoma in adulthood

Meningeal hemangiopericytoma and solitary fibrous tumors carry the NAB2-STAT6 fusion and can be diagnosed by nuclear expression of STAT6 protein

Methylation-based classification of benign and malignant peripheral nerve sheath tumors

Multiple thromboembolic events in fetofetal transfusion syndrome in triplets contributing to the understanding of pathogenesis of hydranencephaly in combination with polymicrogyria

Mutant BRAF V600E protein in ganglioglioma is predominantly expressed by neuronal tumor cells

Mutation-specific IDH1 antibody differentiates oligodendrogliomas and oligoastrocytomas from other brain tumors with oligodendroglioma-like morphology.

Neurofibromin specific antibody differentiates malignant peripheral nerve sheath tumors (MPNST) from other spindle cell neoplasms

New Brain Tumor Entities Emerge from Molecular Classification of CNS-PNETs

Oncogenic KRAS hotspot mutations are rare in IDH-mutant gliomas

Osteonectin expression in surrounding stroma of craniopharyngiomas: association with recurrence rate and brain infiltration

Paired box gene 8 (PAX8) expression is associated with sonic hedgehog (SHH)/wingless int (WNT) subtypes, desmoplastic histology and patient survival in human medulloblastomas

Parenchymal accumulation of CD163+ macrophages/microglia in multiple sclerosis brains

Pitfalls in the assessment of MGMT expression and in its correlation with survival in diffuse astrocytomas: proposal of a feasible immunohistochemical approach.

Pituitary adenomas and craniopharyngiomas are CDX2 negative neoplasms

Prognostic relevance of global histone 3 lysine 9 acetylation in ependymal tumors

Prognostic value of blood flow estimated by arterial spin labeling and dynamic susceptibility contrast-enhanced MR imaging in high-grade gliomas

Prognostic value of blood flow measurements using arterial spin labeling in gliomas

Radiation-induced gliomas represent H3-/IDH-wild type pediatric gliomas with recurrent PDGFRA amplification and loss of CDKN2A/B