Lista de obras - Andreas von Deimling - Dominio Público Uruguay

2-Hydroxyglutarate concentration in serum from patients with gliomas does not correlate with IDH1/2 mutation status or tumor size

artículo científico publicado en 2011

45-year-old male with symptomatic mass in the frontal lobe

artículo científico publicado en 2006

A (CA)n dinucleotide repeat assay for evaluating loss of allelic heterozygosity in small and archival human brain tumor specimens.

artículo científico

A PRDX1-p38α heterodimer amplifies MET-driven invasion of IDH-wildtype and IDH-mutant gliomas

artículo científico publicado en 2018

A device for processing large acrylamide gels.

artículo científico publicado en 1994

A highly conserved processed PTEN pseudogene is located on chromosome band 9p21 ⬇️

artículo científico publicado el 7 de mayo de 1998

A new approach to the molecular basis of neoplastic transformation in the brain

artículo científico publicado el 1 de octubre de 1992

A new clinico-pathological classification system for mesial temporal sclerosis

artículo científico publicado en 2007

A novel human high-risk ependymoma stem cell model reveals the differentiation-inducing potential of the histone deacetylase inhibitor Vorinostat

artículo científico publicado en 2011

A novel, diffusely infiltrative xenograft model of human anaplastic oligodendroglioma with mutations in FUBP1, CIC, and IDH1.

artículo científico publicado en 2013

A phase II, randomized, study of weekly APG101+reirradiation versus reirradiation in progressive glioblastoma

artículo científico publicado en 2014

A polymerase chain reaction-based assay for the rapid detection of gene amplification in human tumors

artículo científico publicado en 1996

A rapid and sensitive protocol for competitive reverse transcriptase (cRT) PCR analysis of cellular genes.

artículo científico publicado en 1998

A role for beta-melanocyte-stimulating hormone in human body-weight regulation

artículo científico publicado en 2006

A subset of pediatric-type thalamic gliomas share a distinct DNA methylation profile, H3K27me3 loss and frequent alteration of EGFR

scientific article published on 01 November 2020

A vaccine targeting mutant IDH1 induces antitumour immunity

artículo científico publicado en 2014

ACTR-05. THE RANDOMIZED PHASE II ARTE TRIAL: BEVACIZUMAB PLUS HYPOFRACTIONATED RADIOTHERAPY VERSUS RADIOTHERAPY ALONE IN ELDERLY PATIENTS WITH NEWLY DIAGNOSED GLIOBLASTOMA.

artículo científico publicado en 2017

ACTR-61. LONG-TERM ANALYSES OF THE NOA-08 RANDOMIZED PHASE III TRIAL

AKT1E17K mutations cluster with meningothelial and transitional meningiomas and can be detected by SFRP1 immunohistochemistry

artículo científico publicado en 2013

ALK gene translocations and amplifications in brain metastases of non-small cell lung cancer.

artículo científico publicado en 2013

ANGI-08RADIOGENOMIC rCBV-IMAGING VISUALIZES THE DISTINCT ANGIOGENESIS TRANSCRIPTOME SIGNATURES OF IDH MUTANT AND WILD-TYPE GLIOMAS.

artículo científico publicado en 2015

ATIM-20. GAPVAC-101 TRIAL OF A HIGHLY PERSONALIZED PEPTIDE VACCINATION FOR PATIENTS WITH NEWLY DIAGNOSED GLIOBLASTOMA

ATIM-33. NOA-16: A FIRST-IN-MAN MULTICENTER PHASE I CLINICAL TRIAL OF THE GERMAN NEUROONCOLOGY WORKING GROUP EVALUATING A MUTATION-SPECIFIC PEPTIDE VACCINE TARGETING IDH1R132H IN PATIENTS WITH NEWLY DIAGNOSED MALIGNANT ASTROCYTOMAS

ATIM-35. VXM01 PHASE I STUDY IN PATIENTS WITH PROGRESSIVE GLIOBLASTOMA – FINAL RESULTS

ATRX and IDH1-R132H immunohistochemistry with subsequent copy number analysis and IDH sequencing as a basis for an "integrated" diagnostic approach for adult astrocytoma, oligodendroglioma and glioblastoma

artículo científico publicado en 2014

ATRX loss refines the classification of anaplastic gliomas and identifies a subgroup of IDH mutant astrocytic tumors with better prognosis

artículo científico publicado en 2013

Aberrant self-renewal and quiescence contribute to the aggressiveness of glioblastoma

artículo científico publicado en 2014

Absence of immunoglobulin class switch in primary lymphomas of the central nervous system

artículo científico publicado en 2005

Abstract 2182: Preclincial in vitro and in vivo combination therapies for mutant IDH1R132 tumors with BAY 1436032

scholarly article

Abstract 3094: Epigenetic classification of ependymal brain tumors across age groups

Abstract 4736: N-myc downstream regulated gene 1: A novel mediator of hypoxia-driven chemoresistance in glioblastoma

article

Abstracts

article by L. Bie et al published 1 April 2013 in Neuro-Oncology

Abstracts of the 10th Congress of the European Association of NeuroOncology. Marseille, France. September 6-9, 2012

artículo científico publicado en 2012

Accumulation of genomic aberrations during clinical progression of medulloblastoma

artículo científico publicado en 2008

Accumulation of wild type p53 protein in human astrocytomas

scientific article published on 01 August 1993

Accurate calling of KIAA1549-BRAF fusions from DNA of human brain tumours using methylation array-based copy number and gene panel sequencing data

artículo científico publicado en 2020

Actively personalized vaccination trial for newly diagnosed glioblastoma

scientific article published on 19 December 2018

Adamantinomatous and papillary craniopharyngiomas are characterized by distinct epigenomic as well as mutational and transcriptomic profiles

artículo científico publicado en 2016

Adaptation of cancer cells from different entities to the MDM2 inhibitor nutlin-3 results in the emergence of p53-mutated multi-drug-resistant cancer cells.

artículo científico publicado en 2011

Addressing diffuse glioma as a systemic brain disease with single-cell analysis

artículo científico publicado en 2011

Adult IDH wild type astrocytomas biologically and clinically resolve into other tumor entities

artículo científico publicado en 2015

Adult and pediatric medulloblastomas are genetically distinct and require different algorithms for molecular risk stratification

artículo científico publicado en 2010

Adult medulloblastoma comprises three major molecular variants.

artículo científico publicado en 2011

Aggressive Hematopoietic Malignancy Characterized by Biallelic Loss of SMARCB1

artículo científico publicado en 2020

Allelic losses on chromosomes 14, 10, and 1 in atypical and malignant meningiomas: a genetic model of meningioma progression

scientific article published on 01 October 1995

Alterations in molecular pathways of diffusely infiltrating glial neoplasms: application to tumor classification and anti-tumor therapy (Review).

artículo científico publicado en 2003

Alterations of cell cycle regulators in gliomatosis cerebri

artículo científico publicado en 2005

Amplification and overexpression of CMET is a common event in brain metastases of non-small cell lung cancer

artículo científico publicado en 2014

Amplification of the PLAG-family genes-PLAGL1 and PLAGL2-is a key feature of the novel tumor type CNS embryonal tumor with PLAGL amplification

artículo científico publicado en 2023

Amplification of the cyclin-dependent kinase 4 (CDK4) gene is associated with high cdk4 protein levels in glioblastoma multiforme.

artículo científico publicado en 1996

An endogenous tumour-promoting ligand of the human aryl hydrocarbon receptor

artículo científico publicado en 2011

An optimized protocol for mRNA quantification using nested competitive RT-PCR

artículo científico publicado en 1997

An optimized workflow to improve reliability of detection of KIAA1549:BRAF fusions from RNA sequencing data

artículo científico publicado en 2020

Analysis of BRAF V600E mutation in 1,320 nervous system tumors reveals high mutation frequencies in pleomorphic xanthoastrocytoma, ganglioglioma and extra-cerebellar pilocytic astrocytoma

artículo científico publicado en 2011

Analysis of CIC-associated CpG island methylation in oligoastrocytoma.

artículo científico publicado en 2013

Analysis of IDH mutation, 1p/19q deletion, and PTEN loss delineates prognosis in clinical low-grade diffuse gliomas

artículo científico publicado en 2014

Analysis of TP53 and PTEN in gliomatosis cerebri

artículo científico publicado en 2003

Analysis of a Surgical Series of 21 Cerebral Radiation Necroses

artículo científico publicado en 2020

Analysis of the IDH1 codon 132 mutation in brain tumors

artículo científico publicado en 2008

Analysis of the MEN1 gene in sporadic pituitary adenomas

artículo científico publicado en 1999

Analysis of the PTEN gene in human meningiomas

article

Analysis of the RET, GDNF, EDN3, and EDNRB genes in patients with intestinal neuronal dysplasia and Hirschsprung disease.

artículo científico publicado en 2001

Anaplastic astrocytoma with piloid features, a novel molecular class of IDH wildtype glioma with recurrent MAPK pathway, CDKN2A/B and ATRX alterations

artículo científico publicado en 2018

Announcing cIMPACT-NOW: the Consortium to Inform Molecular and Practical Approaches to CNS Tumor Taxonomy

artículo científico publicado en 2016

Application of a BRAF V600E mutation-specific antibody for the diagnosis of hairy cell leukemia

artículo científico publicado en 2012

Application of mutant IDH1 antibody to differentiate diffuse glioma from nonneoplastic central nervous system lesions and therapy-induced changes

artículo científico publicado en 2010

Array-based DNA-methylation profiling in sarcomas with small blue round cell histology provides valuable diagnostic information

artículo científico publicado en 2018

Assessment and prognostic significance of the epidermal growth factor receptor vIII mutation in glioblastoma patients treated with concurrent and adjuvant temozolomide radiochemotherapy

artículo científico publicado en 2014

Assessment of BRAF V600E mutation status by immunohistochemistry with a mutation-specific monoclonal antibody

artículo científico publicado en 2011

Assessment of Melanin Content and its Influence on Susceptibility Contrast in Melanoma Metastases

artículo científico publicado en 2019

Assessment of tumor cell invasion factors in gliomatosis cerebri

artículo científico publicado en 2005

Association Between Tumor Compartment Volumes, the Incidence of Pretreatment Seizures, and Statin-Mediated Protective Effects in Glioblastoma

scientific article published on 01 October 2019

Association between fluorine-18-labeled fluorodeoxyglucose uptake and 1p and 19q loss of heterozygosity in World Health Organization Grade II gliomas.

artículo científico publicado en 2007

Association of EGFR Gene Amplification and CDKN2 (p16/MTS1) Gene Deletion in Glioblastoma Multiforme ⬇️

artículo científico publicado el 1 de julio de 1997

Association of allelic losses on human chromosomal arms 11q and 16q in sporadic breast cancer

artículo científico publicado en 1996

Association of epidermal growth factor receptor gene amplification with loss of chromosome 10 in human glioblastoma multiforme

artículo científico publicado el 1 de agosto de 1992

Association of loss of heterozygosity on chromosome 17p with high platelet-derived growth factor alpha receptor expression in human malignant gliomas.

artículo científico publicado en 1996

Astrocytic gliomas: characterization on a molecular genetic basis.

artículo científico publicado en 1994

Atypical Teratoid/Rhabdoid Tumors Are Comprised of Three Epigenetic Subgroups with Distinct Enhancer Landscapes

artículo científico publicado en 2016

Automated quantitative tumour response assessment of MRI in neuro-oncology with artificial neural networks: a multicentre, retrospective study

artículo científico publicado en 2019

BRAF V600E Mutations in Multiple Myeloma: Clinical and Therapeutic Implications ⬇️

artículo científico publicado en 2012

BRAF V600E Mutations in Nevi and Melanocytic Tumors of Uncertain Malignant Potential

artículo científico publicado en 2018

BRAF V600E analysis for the differentiation of papillary craniopharyngiomas and Rathke's cleft cysts.

artículo científico publicado en 2015

BRAF V600E expression and distribution in desmoplastic infantile astrocytoma/ganglioglioma.

artículo científico publicado en 2014

BRAF V600E-specific immunohistochemistry for the exclusion of Lynch syndrome in MSI-H colorectal cancer

artículo científico publicado en 2013

BRAF V600E-specific immunohistochemistry reveals low mutation rates in biliary tract cancer and restriction to intrahepatic cholangiocarcinoma

artículo científico publicado en 2013

BRAF(V600E) protein expression and outcome from BRAF inhibitor treatment in BRAF(V600E) metastatic melanoma.

artículo científico publicado en 2013

BRAF-mutated pleomorphic xanthoastrocytoma is associated with temporal location, reticulin fiber deposition and CD34 expression

artículo científico publicado en 2014

BRAFV600E immunohistochemistry facilitates universal screening of colorectal cancers for Lynch syndrome

artículo científico publicado en 2013

BRAFV600E mutant protein is expressed in cells of variable maturation in Langerhans cell histiocytosis.

artículo científico publicado en 2012

BRAFV600E-mutation is invariably present and associated to oncogene-induced senescence in Erdheim-Chester disease

artículo científico publicado en 2014

Bevacizumab plus hypofractionated radiotherapy versus radiotherapy alone in elderly patients with glioblastoma: the randomized, open-label, phase II ARTE trial

artículo científico publicado en 2018

Biological and clinical heterogeneity of MYCN-amplified medulloblastoma.

artículo científico publicado en 2011

Biomarker and Histopathology Evaluation of Patients with Recurrent Glioblastoma Treated with Galunisertib, Lomustine, or the Combination of Galunisertib and Lomustine

artículo científico publicado en 2017

Bone marrow biopsies of patients with hematopoietic and lymphoid disorders - epidemiology, chromosomal aberrations and molecular pathology

artículo científico publicado en 2012

Brain metastases: pathobiology and emerging targeted therapies.

artículo científico publicado en 2012

Brain slice invasion model reveals genes differentially regulated in glioma invasion.

artículo científico publicado en 2005

Brain tumour cells interconnect to a functional and resistant network

artículo científico publicado en 2015

CDKN2/p16 or RB alterations occur in the majority of glioblastomas and are inversely correlated.

artículo científico publicado en 1996

CDKN2A/B homozygous deletion is associated with early recurrence in meningiomas

scientific article published on 08 July 2020

CIC and FUBP1 mutations in oligodendrogliomas, oligoastrocytomas and astrocytomas

artículo científico publicado en 2012

CIC protein instability contributes to tumorigenesis in glioblastoma

artículo científico publicado en 2019

CSIG-27. DIFFERENTIAL ELEVATION OF TERT ACTIVITY AND SENSITIVITY TO TEMOZOLOMIDE BY TYPE OF TERT MUTATION IN MGMT PROMOTER-METHYLATED GLIOBLASTOMA

Calcifying fibrous tumor and inflammatory myofibroblastic tumor are epigenetically related: A comparative genome-wide methylation study

scientific article published on 03 June 2019

Carbon ion radiation therapy for high-risk meningiomas

artículo científico publicado en 2010

Cellular localization of pituitary adenylate cyclase-activating peptide (PACAP) following traumatic brain injury in humans

artículo científico publicado en 2007

Central neurocytoma: histopathological variants and therapeutic approaches ⬇️

artículo científico publicado el 1 de enero de 1992

Cerebrospinal Fluid cfDNA Sequencing for Classification of Central Nervous System Glioma

artículo científico publicado en 2024

Characterization of R132H mutation-specific IDH1 antibody binding in brain tumors

artículo científico publicado en 2009

Characterization of novel and complex genomic aberrations in glioblastoma using a 32K BAC array

artículo científico publicado en 2009

Characterization of the amplicon on chromosomal segment 4q12 in glioblastoma multiforme

artículo científico publicado en 2007

Characterization of the epithelial membrane protein 3 interaction network reveals a potential functional link to mitogenic signal transduction regulation

scientific article published on 20 January 2019

Characterization of the human Rad51 genomic locus and examination of tumors with 15q14-15 loss of heterozygosity (LOH)

artículo científico publicado en 1999

Characterization of the somatic mutational spectrum of the neurofibromatosis type 1 (NF1) gene in neurofibromatosis patients with benign and malignant tumors.

artículo científico publicado en 2004

Chemoradiotherapy of newly diagnosed glioblastoma with intensified temozolomide

artículo científico publicado en 2009

Chemotherapy with BCNU in recurrent glioma: Analysis of clinical outcome and side effects in chemotherapy-naïve patients

artículo científico publicado en 2015

Chordoid meningiomas can be sub-stratified into prognostically distinct DNA methylation classes and are enriched for heterozygous deletions of chromosomal arm 2p

artículo científico publicado en 2018

Choreoathetosis, hypothyroidism, and pulmonary alterations due to human NKX2-1 haploinsufficiency

artículo científico publicado en 2002

Chromogenic in situ hybridization is a reliable alternative to fluorescence in situ hybridization for diagnostic testing of 1p and 19q loss in paraffin-embedded gliomas

artículo científico publicado en 2012

Chromosomal imbalances and NF2 mutational analysis in a series of 10 spinal nerve sheath myxomas.

artículo científico publicado en 2007

Chromosomal imbalances in brain metastases of solid tumors

artículo científico publicado en 2000

Chromosome 19q Deletions in Human Gliomas Overlap Telomeric to D19S219 and May Target a 425 kb Region Centromeric to D19S112 ⬇️

artículo científico publicado el 1 de septiembre de 1995

Chromosome 22 tiling-path array-CGH analysis identifies germ-line- and tumor-specific aberrations in patients with glioblastoma multiforme

artículo científico publicado en 2005

Clear cell meningiomas are defined by a highly distinct DNA methylation profile and mutations in SMARCE1

artículo científico publicado en 2020

Clinical Significance of Molecular Diagnosis of Pilocytic Astrocytoma: A Case Report

scientific article published on 05 June 2019

Clinical neuropathology practice news 2-2012: BRAF V600E testing

artículo científico publicado en 2012

Clinicopathologic and molecular features of intracranial desmoplastic small round cell tumors

artículo científico publicado en 2019

Clonal BRAF mutations in melanocytic nevi and initiating role of BRAF in melanocytic neoplasia

artículo científico publicado en 2013

Clonal analysis in glioblastoma with epithelial differentiation.

artículo científico publicado en 2001

Clonal analysis in recurrent astrocytic, oligoastrocytic and oligodendroglial tumors implicates IDH1- mutation as common tumor initiating event

artículo científico publicado en 2012

Clonality of multiple meningiomas

scientific article published on 01 May 1997

Combined 1p/19q loss in oligodendroglial tumors: predictive or prognostic biomarker?

artículo científico publicado en 2007

Combined BRAF(V600E)-positive melanocytic lesions with large epithelioid cells lacking BAP1 expression and conventional nevomelanocytes

artículo científico publicado en 2013

Combined molecular analysis of BRAF and IDH1 distinguishes pilocytic astrocytoma from diffuse astrocytoma.

artículo científico publicado en 2009

Common regions of deletion on chromosome 22q12.3-q13.1 and 22q13.2 in human astrocytomas appear related to malignancy grade.

artículo científico publicado en 1999

Comparative analysis of the NF2, TP53, PTEN, KRAS, NRAS and HRAS genes in sporadic and radiation-induced human meningiomas

scientific article published on 01 October 2001

Comparative evaluation of T-cell receptors in experimental glioma-draining lymph nodes

artículo científico publicado en 2021

Comparative integrated molecular analysis of intraocular medulloepitheliomas and central nervous system embryonal tumors with multilayered rosettes confirms that they are distinct nosologic entities

artículo científico publicado en 2015

Comparative molecular analysis of primary and recurrent oligodendroglioma that acquired imbalanced 1p/19q codeletion and TP53 mutation: a case report

artículo científico publicado en 2020

Comparison of automated silver enhanced in situ hybridization and fluorescence in situ hybridization for evaluation of epidermal growth factor receptor status in human glioblastomas

artículo científico publicado en 2009

Comparison of immunohistochemistry, DNA sequencing and allele-specific PCR for the detection of IDH1 mutations in gliomas.

artículo científico publicado en 2012

Comprehensive Analysis of Alternative Splicing Across Tumors from 8,705 Patients

artículo científico

Comprehensive Characterization of Cancer Driver Genes and Mutations

article

Comprehensive, Integrative Genomic Analysis of Diffuse Lower-Grade Gliomas

artículo científico publicado en 2015

Constitutive IDO expression in human cancer is sustained by an autocrine signaling loop involving IL-6, STAT3 and the AHR.

artículo científico publicado en 2014

Copy number variation analysis and methylome profiling of a GNAQ-mutant primary meningeal melanocytic tumor and its liver metastasis.

artículo científico publicado en 2016

Correction to: DNA methylation-based reclassification of olfactory neuroblastoma

artículo científico publicado en 2018

Correction: A Novel, Diffusely Infiltrative Xenograft Model of Human Anaplastic Oligodendroglioma with Mutations in FUBP1, CIC, and IDH1.

artículo científico publicado en 2013

Correction: Nbn and Atm Cooperate in a Tissue and Developmental Stage-Specific Manner to Prevent Double Strand Breaks and Apoptosis in Developing Brain and Eye.

artículo científico publicado en 2013

Correlated MRI and Ultramicroscopy (MR-UM) of Brain Tumors Reveals Vast Heterogeneity of Tumor Infiltration and Neoangiogenesis in Preclinical Models and Human Disease

Corrigendum: Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma

artículo científico publicado en 2012

Cross-Species Genomics Reveals Oncogenic Dependencies in ZFTA/C11orf95 Fusion–Positive Supratentorial Ependymomas

artículo científico publicado en 2021

Cytotoxic T Cells and their Activation Status are Independent Prognostic Markers in Meningiomas

artículo científico publicado en 2019

D-2-Hydroxyglutarate producing neo-enzymatic activity inversely correlates with frequency of the type of isocitrate dehydrogenase 1 mutations found in glioma

artículo científico publicado en 2014

DNA Methylation Profiling Identifies Distinct Clusters in Angiosarcomas

artículo científico publicado en 2019

DNA hybridization subtraction: differences detected between BALB/cAnPt and BALB/cJax at the DNA level

DNA hypermethylation and aberrant expression of the EMP3 gene at 19q13.3 in Human Gliomas

artículo científico publicado en 2007

DNA methylation profiling distinguishes Ewing-like sarcoma with EWSR1-NFATc2 fusion from Ewing sarcoma

scientific article published on 20 March 2019

DNA methylation profiling is a method of choice for molecular verification of pediatric WNT-activated medulloblastomas

artículo científico publicado en 2019

DNA methylation profiling to predict recurrence risk in meningioma: development and validation of a nomogram to optimize clinical management

scientific article published on 01 July 2019

DNA methylation-based classification and grading system for meningioma: a multicentre, retrospective analysis

artículo científico publicado en 2017

DNA methylation-based classification of central nervous system tumours

artículo científico publicado en 2018

DNA methylation-based classification of ependymomas in adulthood: implications for diagnosis and treatment

artículo científico publicado en 2018

DNA methylation-based classification of malformations of cortical development in the human brain

artículo científico publicado en 2021

DNA methylation-based profiling for paediatric CNS tumour diagnosis and treatment: a population-based study

artículo científico publicado en 2019

DNA methylation-based profiling of uterine neoplasms: a novel tool to improve gynecologic cancer diagnostics

scientific article published on 25 November 2019

DNA methylation-based reclassification of olfactory neuroblastoma

artículo científico publicado en 2018

DNA-methylation profiling discloses significant advantages over NanoString method for molecular classification of medulloblastoma

artículo científico publicado en 2017

Decreased expression of glutamate transporters in astrocytes after human traumatic brain injury

artículo científico publicado en 2006

Decreased expression of the active subunit of the cystine/glutamate antiporter xCT is associated with loss of heterozygosity of 1p in oligodendroglial tumours WHO grade II.

artículo científico publicado en 2009

Decreased hemispheric Aquaporin-4 is linked to evolving brain edema following controlled cortical impact injury in rats.

artículo científico publicado en 2002

Defective p53 antiangiogenic signaling in glioblastoma

artículo científico publicado en 2010

Deletions on the long arm of chromosome 17 in pilocytic astrocytoma.

artículo científico publicado en 1993

Delineation of two clinically and molecularly distinct subgroups of posterior fossa ependymoma

artículo científico publicado en 2011

Design, synthesis and biological activity of 3-pyrazine-2-yl-oxazolidin-2-ones as novel, potent and selective inhibitors of mutant isocitrate dehydrogenase 1.

artículo científico publicado en 2017

Desmoplastic cerebral astrocytomas of infancy: a histopathologic, immunohistochemical, ultrastructural, and molecular genetic study

artículo científico publicado el 1 de diciembre de 1992

Desmoplastic myxoid tumor, SMARCB1-mutant: clinical, histopathological and molecular characterization of a pineal region tumor encountered in adolescents and adults

scientific article published on 16 November 2019

Desmoplastic/nodular medulloblastomas (DNMB) and medulloblastomas with extensive nodularity (MBEN) disclose similar epigenetic signatures but different transcriptional profiles

artículo científico publicado en 2019

Detection of 2-hydroxyglutarate in formalin-fixed paraffin-embedded glioma specimens by gas chromatography/mass spectrometry

artículo científico

Detection of BRAF V600E mutations in skin metastases of malignant melanoma by monoclonal antibody VE1

artículo científico publicado en 2012

Detection of BRAF p.V600E Mutations in Melanoma by Immunohistochemistry Has a Good Interobserver Reproducibility

artículo científico publicado en 2013

Detection of BRAF p.V600E mutations in melanomas: comparison of four methods argues for sequential use of immunohistochemistry and pyrosequencing.

artículo científico publicado en 2012

Detection of IDH1 mutations in gliomatosis cerebri, but only in tumors with additional solid component: evidence for molecular subtypes.

artículo científico publicado en 2010

Detection of isocitrate dehydrogenase 1 mutation R132H in myelodysplastic syndrome by mutation-specific antibody and direct sequencing

artículo científico publicado en 2010

Detection of methylation in promoter sequences by melting curve analysis-based semiquantitative real time PCR.

artículo científico publicado en 2008

Detection of the BRAF V600E mutation in serous ovarian tumors: a comparative analysis of immunohistochemistry with a mutation-specific monoclonal antibody and allele-specific PCR.

artículo científico

Diagnostic Challenges in Meningioma

artículo científico

Diagnostic Value of Immunohistochemistry for the Detection of the BRAFV600E Mutation in Papillary Thyroid Carcinoma: Comparative Analysis with Three DNA-Based Assays

article

Diagnostic accuracy of DW MR imaging in the differentiation of chordomas and chondrosarcomas of the skull base: A 3.0-T MRI study of 105 cases

artículo científico publicado en 2018

Diagnostic value of immunohistochemistry for the detection of the BRAFV600E mutation in primary lung adenocarcinoma Caucasian patients.

artículo científico publicado en 2012

Diagnostic, prognostic and predictive relevance of molecular markers in gliomas

artículo científico

Differential concentration-dependent effects of prolonged norepinephrine infusion on intraparenchymal hemorrhage and cortical contusion in brain-injured rats.

artículo científico publicado en 2003

Differential nuclear ATRX expression in sarcomas

artículo científico publicado en 2015

Differentially expressed genes in neurofibromatosis 1-associated neurofibromas and malignant peripheral nerve sheath tumors

artículo científico publicado en 2003

Diffuse Astrocytoma, IDH-Wildtype: A Dissolving Diagnosis

artículo científico publicado en 2018

Dissecting the genomic complexity underlying medulloblastoma

artículo científico publicado en 2012

Distinct requirement for an intact dimer interface in wild-type, V600E and kinase-dead B-Raf signalling

artículo científico publicado en 2012

Distribution of EGFR amplification, combined chromosome 7 gain and chromosome 10 loss, and TERT promoter mutation in brain tumors and their potential for the reclassification of IDHwt astrocytoma to glioblastoma

scientific article published on 05 September 2018

Distribution of TERT promoter mutations in pediatric and adult tumors of the nervous system

artículo científico publicado en 2013

Down-regulation of the inhibitor of growth 1 (ING1) tumor suppressor sensitizes p53-deficient glioblastoma cells to cisplatin-induced cell death

artículo científico publicado en 2007

Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma

artículo científico publicado en 2012

Durable Control of Metastatic AKT1-Mutant WHO Grade 1 Meningothelial Meningioma by the AKT Inhibitor, AZD5363.

artículo científico publicado en 2017

EANO guidelines for the diagnosis and treatment of meningiomas

artículo científico publicado en 2016

EANO guidelines on the diagnosis and treatment of diffuse gliomas of adulthood

scientific article published on 08 December 2020

EG-09EPIGENETIC PROFILING REVEALS A CpG HYPERMETHYLATION PHENOTYPE (CIMP) ASSOCIATED WITH WORSE PROGRESSION-FREE SURVIVAL IN MENINGIOMA.

artículo científico publicado en 2014

EGFL7 enhances surface expression of integrin αβ to promote angiogenesis in malignant brain tumors

artículo científico publicado en 2018

EGFR and erbB2 in malignant peripheral nerve sheath tumors and implications for targeted therapy

artículo científico publicado en 2008

Early expression of glutamate transporter proteins in ramified microglia after controlled cortical impact injury in the rat.

artículo científico publicado en 2001

Ectopic intracranial retinoblastoma in a 3.5-month-old infant without eye involvement and without evidence of heritability

artículo científico publicado en 2019

Effector T-cell infiltration positively impacts survival of glioblastoma patients and is impaired by tumor-derived TGF-β.

artículo científico publicado en 2011

Effects of barium on stimulus-induced rises of [K+]o in human epileptic non-sclerotic and sclerotic hippocampal area CA1.

artículo científico publicado en 2000

Embryonal tumor with abundant neuropil and true rosettes (ETANTR), ependymoblastoma, and medulloepithelioma share molecular similarity and comprise a single clinicopathological entity

artículo científico publicado en 2013

Endometrial stromal sarcomas with BCOR-rearrangement harbor MDM2 amplifications

scientific article published on 30 April 2020

Enhancer hijacking activates GFI1 family oncogenes in medulloblastoma

artículo científico publicado en 2014

Enzastaurin before and concomitant with radiation therapy, followed by enzastaurin maintenance therapy, in patients with newly diagnosed glioblastoma without MGMT promoter hypermethylation

scientific article published on August 2013

Enzymatic assay for quantitative analysis of (D)-2-hydroxyglutarate

artículo científico publicado en 2012

Epidermal Nbn deletion causes premature hair loss and a phenotype resembling psoriasiform dermatitis

artículo científico publicado en 2016

Epigenetic silencing of death receptor 4 mediates tumor necrosis factor-related apoptosis-inducing ligand resistance in gliomas

artículo científico publicado en 2009

Epigenetically mediated downregulation of the differentiation-promoting chaperon protein CRABP2 in astrocytic gliomas

artículo científico publicado en 2012

Epigenomic alterations define lethal CIMP-positive ependymomas of infancy

artículo científico publicado en 2014

Epithelioid glioblastomas stratify into established diagnostic subsets upon integrated molecular analysis.

artículo científico publicado en 2017

Erratum to: Gliomatosis cerebri: no evidence for a separate brain tumor entity

artículo científico publicado en 2016

Establishment and application of a novel patient-derived KIAA1549:BRAF-driven pediatric pilocytic astrocytoma model for preclinical drug testing

artículo científico publicado en 2016

Estimating cancer survival and clinical outcome based on genetic tumor progression scores

artículo científico publicado en 2005

Ets-1 is up-regulated together with its target gene products matrix metalloproteinase-2 and matrix metalloproteinase-9 in atypical and anaplastic meningiomas.

artículo científico publicado en 2006

Evaluation of a novel liquid embolic agent (precipitating hydrophobic injectable liquid (PHIL)) in an animal endovascular embolization model

artículo científico publicado en 2017

Evaluation of microvascular permeability with dynamic contrast-enhanced MRI for the differentiation of primary CNS lymphoma and glioblastoma: radiologic-pathologic correlation.

artículo científico publicado en 2014

Evidence for a tumor suppressor gene on chromosome 19q associated with human astrocytomas, oligodendrogliomas, and mixed gliomas ⬇️

artículo científico publicado el 1 de agosto de 1992

Evidence for subarachnoid spread in the development of multiple meningiomas

artículo científico publicado en 1995

Evidence of H3 K27M mutations in posterior fossa ependymomas

artículo científico publicado en 2016

Evolutionary Trajectories of IDH Glioblastomas Reveal a Common Path of Early Tumorigenesis Instigated Years ahead of Initial Diagnosis

artículo científico publicado en 2019

Expression of BRAF V600E mutant protein in epithelial ovarian tumors.

artículo científico

Expression of Epstein-Barr virus membrane antigen gp350/220 in E. coli and in insect cells

artículo científico publicado el 1 de noviembre de 1992

Expression of PACAP and glutamate transporter proteins in satellite oligodendrocytes of the human CNS.

artículo científico publicado en 2007

Expression of alpha B-crystallin in human brain tumors.

artículo científico publicado en 1993

Expression of glucose transporter 1 is associated with loss of heterozygosity of chromosome 1p in oligodendroglial tumors WHO grade II.

artículo científico publicado en 2008

Expression of theATM gene is significantly reduced in sporadic breast carcinomas ⬇️

artículo científico publicado el 29 de octubre de 1998

Expression-based intrinsic glioma subtypes are prognostic in low-grade gliomas of the EORTC22033-26033 clinical trial.

artículo científico publicado en 2018

Extensive Molecular and Clinical Heterogeneity in Patients With Histologically Diagnosed CNS-PNET Treated as a Single Entity: A Report From the Children's Oncology Group Randomized ACNS0332 Trial

artículo científico publicado en 2018

Extent of Resection, MGMT Promoter Methylation Status and Tumor Location Independently Predict Progression-Free Survival in Adult Sporadic Pilocytic Astrocytoma

artículo científico publicado en 2019

Extra-small dual-lumen micro-balloon catheters can improve endovascular embolization: an experimental in vivo and in vitro study

scientific article published on 19 March 2018

FGFR1:TACC1 fusion is a frequent event in molecularly defined extraventricular neurocytoma.

artículo científico publicado en 2018

FOCAD loss impacts microtubule assembly, G2/M progression and patient survival in astrocytic gliomas

scientific article published on 31 August 2019

FSTL5 is a marker of poor prognosis in non-WNT/non-SHH medulloblastoma

artículo científico publicado en 2011

Farewell to oligoastrocytoma: in situ molecular genetics favor classification as either oligodendroglioma or astrocytoma

artículo científico publicado en 2014

Farewell to oligoastrocytoma: response to letters

artículo científico publicado en 2014

Feasibility of real-time molecular profiling for patients with newly diagnosed glioblastoma without MGMT promoter-hypermethylation - the NCT Neuro Master Match (N2M2) pilot study

artículo científico publicado en 2017

Fine mapping of chromosome 22q tumor suppressor gene candidate regions in astrocytoma

artículo científico publicado en 2004

Fluorescein-stained confocal laser endomicroscopy versus conventional frozen section for intraoperative histopathological assessment of intracranial tumors

artículo científico publicado en 2024

Focal genomic amplification at 19q13.42 comprises a powerful diagnostic marker for embryonal tumors with ependymoblastic rosettes.

artículo científico publicado en 2010

Frame-based stereotactic biopsies using an intraoperative MR-scanner are as safe and effective as conventional stereotactic procedures

scientific article published in PLoS ONE

Frequent loss of chromosome 14 in atypical and malignant meningioma: identification of a putative 'tumor progression' locus

artículo científico publicado en 1997

Functional MHC Class II Is Upregulated in Neurofibromin-Deficient Schwann Cells

scientific article published on 10 January 2013

G3BPs tether the TSC complex to lysosomes and suppress mTORC1 signaling

artículo científico publicado en 2021

GE-07DNA METHYLATION IN MEDULLOBLASTOMA AND MOLECULAR DIAGNOSTICS OF BRAIN TUMORS.

artículo científico publicado en 2015

GE-30OLIGOASTROCYTOMA DOES NOT EXIST: IN-SITU MOLECULAR GENETICS FAVORS CLASSIFICATION AS EITHER OLIGODENDROGLIOMA OR ASTROCYTOMA.

artículo científico publicado en 2014

GENE-06. DISTINCT MOLECULAR SUBGROUPS OF TUMORS OF THE PINEAL REGION CORRELATE WITH CLINICAL PARAMETERS AND GENETIC ALTERATIONS

artículo científico publicado en 2019

GENE-07. MOLECULAR NEUROPATHOLOGY 2.0 - INCREASING DIAGNOSTIC ACCURACY IN PEDIATRIC NEUROONCOLOGY.

artículo científico publicado en 2017

GENE-08. THE MNP 2.0 STUDY: PROSPECTIVE INTEGRATION OF DNA METHYLATION PROFILING IN CNS TUMOR DIAGNOSTICS

GENE-12. ANAPLASTIC NEUROEPITHELIAL TUMOR WITH CONDENSED NUCLEI (ANTCON): A NOVEL BRAIN TUMOR ENTITY WITH RECURRENT NTRK FUSION

GRHL1 acts as tumor suppressor in neuroblastoma and is negatively regulated by MYCN and HDAC3.

artículo científico publicado en 2014

Gain of 12p encompassing CCND2 is associated with gemistocytic histology in IDH mutant astrocytomas

artículo científico publicado en 2016

Gene expression-based classification of malignant gliomas correlates better with survival than histological classification.

artículo científico publicado en 2003

Gene regulation by methylation

artículo científico publicado en 2009

Genetic alterations commonly found in diffusely infiltrating cerebral gliomas are rare or absent in pleomorphic xanthoastrocytomas

artículo científico publicado en 2002

Genetic and epigenetic characterization of posterior pituitary tumors

artículo científico publicado en 2021

Genetic signature of oligoastrocytomas correlates with tumor location and denotes distinct molecular subsets

artículo científico publicado en 2002

Genome sequencing of SHH medulloblastoma predicts genotype-related response to smoothened inhibition

artículo científico publicado en 2014

Genome sequencing of pediatric medulloblastoma links catastrophic DNA rearrangements with TP53 mutations

artículo científico publicado en 2012

Genome-wide methylation profiling and copy number analysis in atypical fibroxanthomas and pleomorphic dermal sarcomas indicate a similar molecular phenotype

article published in 2019

Genomic deletions in the BRCA1, BRCA2 and TP53 regions associate with low expression of the estrogen receptor in sporadic breast carcinoma

scientific article published on 01 June 1997

Germline SDHB-inactivating mutation in gastric spindle cell sarcoma

scientific article published on 05 June 2020

Glioblastoma in Adults: A Society for Neuro-Oncology (SNO) and European Society of Neuro-Oncology (EANO) Consensus Review on Current Management and Future Directions

scientific article published on 24 April 2020

Glioblastoma: pathology, molecular mechanisms and markers

artículo científico

Glioma IDH1 mutation patterns off the beaten track.

artículo científico publicado en 2011

Glioma cell VEGFR-2 confers resistance to chemotherapeutic and antiangiogenic treatments in PTEN-deficient glioblastoma

artículo científico publicado en 2015

Gliomatosis cerebri: no evidence for a separate brain tumor entity

artículo científico publicado en 2015

Grading of Diffuse Astrocytic Gliomas: A Review of Studies Before and After the Advent of IDH Testing

artículo científico publicado en 2018

Grading of diffuse astrocytic gliomas: Broders, Kernohan, Zülch, the WHO… and Shakespeare

artículo científico publicado en 2017

Granulomatous tissue response in germinoma, a diagnostic pitfall in endoscopic biopsy

artículo científico publicado en 2007

Guidelines on management of low-grade gliomas: report of an EFNS-EANO Task Force.

artículo científico publicado en 2010

H3-/IDH-wild type pediatric glioblastoma is comprised of molecularly and prognostically distinct subtypes with associated oncogenic drivers

artículo científico publicado en 2017

HDAC5 and HDAC9 in medulloblastoma: novel markers for risk stratification and role in tumor cell growth

artículo científico publicado en 2010

HG-68COMBINED ALTERATIONS IN MAPK PATHWAY GENES, CDKN2A/B AND ATRX CHARACTERIZE ANAPLASTIC PILOCYTIC ASTROCYTOMA.

artículo científico publicado en 2016

Hereditary tumor syndromes and gliomas

artículo científico publicado en 2009

Hereditary tumor syndromes of the nervous system: overview and rare syndromes.

artículo científico publicado en 1995

Heterogeneity of response to immune checkpoint blockade in hypermutated experimental gliomas

scientific article published on 18 February 2020

High density DNA methylation array is a reliable alternative for PCR-based analysis of the MGMT promoter methylation status in glioblastoma

scientific article published on 11 November 2019

High prevalence of BRAF V600E mutations in Erdheim-Chester disease but not in other non-Langerhans cell histiocytoses.

artículo científico publicado en 2012

High rate of FGFR1 amplifications in brain metastases of squamous and non-squamous lung cancer.

artículo científico publicado en 2013

Highly prevalent TERT promoter mutations in bladder cancer and glioblastoma

artículo científico publicado en 2013

Histologically distinct neuroepithelial tumors with histone 3 G34 mutation are molecularly similar and comprise a single nosologic entity

artículo científico publicado en 2015

Histone 3.3 hotspot mutations in conventional osteosarcomas: a comprehensive clinical and molecular characterization of six H3F3A mutated cases

artículo científico publicado en 2017

Histone deacetylase 8 in neuroblastoma tumorigenesis

artículo científico publicado en 2009

Histopathology and clinical outcome of NF1-associated vs. sporadic malignant peripheral nerve sheath tumors

artículo científico publicado en 2006

Hot spots in dynamic (18)FET-PET delineate malignant tumor parts within suspected WHO grade II gliomas.

artículo científico publicado en 2011

Hotspot mutations in H3F3A and IDH1 define distinct epigenetic and biological subgroups of glioblastoma

artículo científico publicado en 2012

Human neuroblastoma cells with acquired resistance to the p53 activator RITA retain functional p53 and sensitivity to other p53 activating agents.

artículo científico publicado en 2012

IDH mutant diffuse and anaplastic astrocytomas have similar age at presentation and little difference in survival: a grading problem for WHO.

artículo científico publicado en 2015

IDH mutation status is associated with a distinct hypoxia/angiogenesis transcriptome signature which is non-invasively predictable with rCBV imaging in human glioma

artículo científico publicado en 2015

IDH-wildtype glioblastomas and grade III/IV IDH-mutant gliomas show elevated tracer uptake in fibroblast activation protein-specific PET/CT

artículo científico publicado en 2019

IDH1 R132H mutation is a rare event in myeloproliferative neoplasms as determined by a mutation specific antibody

artículo científico publicado en 2010

IDH1 mutant glioma initiating cells are predisposed to apoptosis under endoplasmic reticulum (ER) stress

artículo científico publicado en 2018

IDH1/2 mutations in WHO grade II astrocytomas associated with localization and seizure as the initial symptom

artículo científico publicado en 2012

IDH2 Mutations Define a Unique Subtype of Breast Cancer with Altered Nuclear Polarity

artículo científico publicado en 2016

IL4I1 Is a Metabolic Immune Checkpoint that Activates the AHR and Promotes Tumor Progression

scientific article published on 17 August 2020

IMMU-49. CYTOTOXIC T CELLS AND THEIR ACTIVATION STATUS ARE INDEPENDENT PROGNOSTIC MARKERS IN MENINGIOMAS

article published in 2018

IMMU-54. THE ONCOMETABOLITE R-2-HYDROXYGLUTARATE SUPPRESSES THE INNATE IMMUNE MICROENVIRONMENT OF IDH1-MUTATED GLIOMAS VIA ARYL HYDROCARBON RECEPTOR SIGNALING

IMPS-14PROGNOSTIC ROLE OF REGULATORY T-CELLS IN PRIMARY AND RECURRENT MENINGIOMA.

artículo científico publicado en 2015

INFORMING TREATMENT DECISIONS IN RELAPSED PEDIATRIC MALIGNANCIES USING NEXT-GENERATION DIAGNOSTICS.

artículo científico publicado en 2014

INI1 mutations in meningiomas at a potential hotspot in exon 9

artículo científico publicado en 2001

Identification of CRKII, CFL1, CNTN1, NME2, and TKT as Novel and Frequent T-Cell Targets in Human IDH-Mutant Glioma

artículo científico publicado en 2018

Identification of KIF11 As a Novel Target in Meningioma

scientific article published on 15 April 2019

Identification of T cell target antigens in glioblastoma stem-like cells using an integrated proteomics-based approach in patient specimens

artículo científico publicado en 2017

Identification of Tumor Antigens Among the HLA Peptidomes of Glioblastoma Tumors and Plasma

artículo científico publicado en 2018

Identification of Tumor Antigens Among the HLA Peptidomes of Glioblastoma Tumors and Plasma

artículo científico publicado en 2019

Identification of diagnostic serum protein profiles of glioblastoma patients

artículo científico publicado en 2010

Identification of novel allosteric inhibitors of mutant isocitrate dehydrogenase 1 by cross docking-based virtual screening.

artículo científico publicado en 2017

Identification of novel oligodendroglioma-associated candidate tumor suppressor genes in 1p36 and 19q13 using microarray-based expression profiling

artículo científico publicado en 2006

Identification of subgroups of high-grade oligodendroglial tumors by comparative genomic hybridization.

artículo científico publicado en 1999

Imatinib mesylate (Glivec) inhibits Schwann cell viability and reduces the size of human plexiform neurofibroma in a xenograft model.

artículo científico publicado en 2009

Immature mesenchymal stem cell-like pericytes as mediators of immunosuppression in human malignant glioma

artículo científico publicado en 2013

Immunohistochemical analysis of 1844 human epithelial and haematopoietic tumours and sarcomas for IDH1R132H mutation.

artículo científico publicado en 2011

Immunohistochemical analysis of BRAF(V600E) expression of primary and metastatic melanoma and comparison with mutation status and melanocyte differentiation antigens of metastatic lesions

artículo científico publicado en 2013

Immunohistochemical detection of the BRAF V600E-mutated protein in papillary thyroid carcinoma.

artículo científico publicado en 2012

Immunohistochemical testing of BRAF V600E status in 1,120 tumor tissue samples of patients with brain metastases

artículo científico publicado en 2012

Immunohistochemistry is highly sensitive and specific for the detection of V600E BRAF mutation in melanoma.

artículo científico publicado en 2013

Impact of genotype and morphology on the prognosis of glioblastoma

artículo científico publicado en 2002

Impact of post-surgical freezing delay on brain tumor metabolomics

scientific article published on 13 May 2019

Impaired Pten expression in human malignant peripheral nerve sheath tumours

artículo científico publicado en 2012

Improved correlation of the neuropathologic classification according to adapted world health organization classification and outcome after radiotherapy in patients with atypical and anaplastic meningiomas

artículo científico publicado en 2010

Improved molecular classification of serrated lesions of the colon by immunohistochemical detection of BRAF V600E.

artículo científico publicado en 2013

In situ proximity ligation assay to evaluate presentation of a mutated CD4 epitope in human glioma tissue

scholarly article by Lukas Bunse et al published October 2014 in Journal of Neuroimmunology

Incidence, mortality and outcome of meningiomas: A population-based study from Germany

artículo científico publicado en 2019

Increased Radiation-Associated T-Cell Infiltration in Recurrent IDH-Mutant Glioma

artículo científico publicado en 2020

Increased expression of avian erythroblastosis virus E26 oncogene homolog 1 in World Health Organization grade 1 meningiomas is associated with an elevated risk of recurrence and is correlated with the expression of its target genes matrix metallopr

artículo científico publicado en 2006

Increased levels of 2-hydroxyglutarate in AML patients with IDH1-R132H and IDH2-R140Q mutations

artículo científico publicado en 2010

Increased malignant behavior in neuroblastoma cells with acquired multi-drug resistance does not depend on P-gp expression.

artículo científico publicado en 2005

Increased mitochondrial activity in a novel IDH1-R132H mutant human oligodendroglioma xenograft model: in situ detection of 2-HG and α-KG.

artículo científico publicado en 2013

Infant high grade gliomas comprise multiple subgroups characterized by novel targetable gene fusions and favorable outcomes

scientific article published on 01 April 2020

Infratentorial IDH-mutant astrocytoma is a distinct subtype

artículo científico publicado en 2020

Inhibition of CD95/CD95L Signaling with APG101 Prevents Invasion and Enhances Radiation Therapy for Glioblastoma

artículo científico publicado en 2018

Inhibitors of Mutant Isocitrate Dehydrogenases 1 and 2 (mIDH1/2): An Update and Perspective

artículo científico publicado en 2018

Inositol-requiring enzyme 1alpha is a key regulator of angiogenesis and invasion in malignant glioma

artículo científico publicado en 2010

Instability of short tandem repeats (microsatellites) in human cancers.

artículo científico publicado en 1994

Integrated DNA methylation and copy-number profiling identify three clinically and biologically relevant groups of anaplastic glioma

artículo científico publicado en 2014

Integrated Genomic Classification of Melanocytic Tumors of the Central Nervous System Using Mutation Analysis, Copy Number Alterations, and DNA Methylation Profiling

artículo científico publicado en 2018

Integrated analysis of dynamic FET PET/CT parameters, histology, and methylation profiling of 44 gliomas.

artículo científico publicado en 2018

Integrated analysis of pediatric glioblastoma reveals a subset of biologically favorable tumors with associated molecular prognostic markers

artículo científico publicado en 2015

Integrated molecular analysis of adult sonic hedgehog (SHH)-activated medulloblastomas reveals two clinically relevant tumor subsets with VEGFA as potent prognostic indicator

artículo científico publicado en 2021

Integrated molecular characterization of IDH-mutant glioblastomas

artículo científico publicado en 2018

Integrative analysis reveals early and distinct genetic and epigenetic changes in intraductal papillary and tubulopapillary cholangiocarcinogenesis

artículo científico publicado en 2021

Interdisciplinary approach allows minimally invasive, nerve-sparing removal of retroperitoneal peripheral nerve sheath tumors

artículo científico publicado en 2020

Interlaboratory comparison of IDH mutation detection.

artículo científico

International Society Of Neuropathology--Haarlem consensus guidelines for nervous system tumor classification and grading

artículo científico

Interorgan shift of nitrosamine metabolism by dietary ethanol

scientific article published on 01 January 1987

Intracranial thermotherapy using magnetic nanoparticles combined with external beam radiotherapy: results of a feasibility study on patients with glioblastoma multiforme.

artículo científico publicado en 2006

Intraoperative radiofrequency ablation of lung metastases and histologic evaluation

scientific article published on 01 February 2009

Intrathecal activation of CD8<sup>+</sup> memory T cells in IgG4-related disease of the brain parenchyma

artículo científico publicado en 2021

Intraventricular meningiomas frequently harbor NF2 mutations but lack common genetic alterations in TRAF7, AKT1, SMO, KLF4, PIK3CA, and TERT

artículo científico publicado en 2019

Investigation of germline GFR alpha-1 mutations in Hirschsprung disease.

artículo científico publicado en 1999

Involvement of Hif-1 in desferrioxamine-induced invasion of glioblastoma cells

artículo científico publicado en 2007

Isocitrate dehydrogenase 1 mutant R132H sensitizes glioma cells to BCNU-induced oxidative stress and cell death

artículo científico publicado en 2013

Isocitrate dehydrogenase mutations: a challenge to traditional views on the genesis and malignant progression of gliomas

artículo científico publicado en 2011

Isomorphic diffuse glioma is a morphologically and molecularly distinct tumour entity with recurrent gene fusions of MYBL1 or MYB and a benign disease course

artículo científico publicado en 2019

K27M mutation in histone H3.3 defines clinically and biologically distinct subgroups of pediatric diffuse intrinsic pontine gliomas

artículo científico publicado en 2012

K27M-mutant histone-3 as a novel target for glioma immunotherapy

artículo científico publicado en 2017

Kaposiform hemangioendothelioma and tufted angioma - (epi)genetic analysis including genome-wide methylation profiling

scientific article published on 10 December 2019

LG-27DKFZ-BT66 - A NOVEL PILOCYTIC ASTROCYTOMA MODEL FOR PRECLINICAL DRUG TESTING.

artículo científico publicado en 2016

LGG-04. CHARACTERIZATION OF ONCOGENE-INDUCED SENESCENCE AND THE ROLE OF THE SENESCENCE-ASSOCIATED SECRETORY PHENOTYPE IN PILOCYTIC ASTROCYTOMA.

artículo científico publicado en 2017

LGG-11. REGULATION OF ONCOGENE-INDUCED SENESCENCE IN PILOCYTIC ASTROCYTOMA.

artículo científico publicado en 2018

LGG-13. PAPILLARY GLIONEURONAL TUMOR (PGNT) EXHIBITS A CHARACTERISTIC METHYLATION PROFILE AND MANDATORY FUSIONS INVOLVING PRKCA

LGG-20. MOLECULARLY-DEFINED DIFFUSE LEPTOMENINGEAL GLIONEURONAL TUMOR (DLGNT) COMPRISES TWO SUBGROUPS WITH DISTINCT CLINICAL AND GENETIC FEATURES

LIN28A immunoreactivity is a potent diagnostic marker of embryonal tumor with multilayered rosettes (ETMR)

artículo científico publicado en 2012

LOC283731 promoter hypermethylation prognosticates survival after radiochemotherapy in IDH1 wild-type glioblastoma patients

artículo científico publicado en 2016

Laser-assisted microdissection, techniques and applications in pathology (review).

artículo científico publicado en 2005

Ligands for PPARgamma and RAR cause induction of growth inhibition and apoptosis in human glioblastomas

artículo científico publicado en 2003

Localization of Blvr, biliverdin reductase, on mouse chromosome 2

scientific article published on 01 August 1989

Location-Dependent Patient Outcome and Recurrence Patterns in IDH1-Wildtype Glioblastoma

Loci associated with malignant progression in astrocytomas: a candidate on chromosome 19q.

artículo científico publicado en 1994

Lomustine and Bevacizumab in Progressive Glioblastoma

artículo científico publicado en 2017

Long-Term Outcome After Radiotherapy in Patients With Atypical and Malignant Meningiomas—Clinical Results in 85 Patients Treated in a Single Institution Leading to Optimized Guidelines for Early Radiation Therapy

artículo científico publicado en 2011

Long-term survival in primary glioblastoma with versus without isocitrate dehydrogenase mutations

artículo científico publicado en 2013

Long-term survival of glioblastoma multiforme: importance of histopathological reevaluation.

artículo científico publicado en 2000

Long-term survival with glioblastoma multiforme

artículo científico publicado en 2007

Loss of FUBP1 expression in gliomas predicts FUBP1 mutation and is associated with oligodendroglial differentiation, IDH1 mutation and 1p/19q loss of heterozygosity.

artículo científico publicado en 2014

Loss of Mpdz impairs ependymal cell integrity leading to perinatal-onset hydrocephalus in mice.

artículo científico publicado en 2017

Loss of NF1 alleles distinguish sporadic from NF1-associated pilocytic astrocytomas.

artículo científico publicado en 2001

Loss of histone H3K27me3 identifies a subset of meningiomas with increased risk of recurrence

artículo científico publicado en 2018

Loss of maternal alleles on chromosome arm 11p in hepatoblastoma

scientific article published on 01 October 1994

Low frequency of SV40, JC and BK polyomavirus sequences in human medulloblastomas, meningiomas and ependymomas.

artículo científico publicado en 2000

MAP kinase activity supported by BRAF (V600E) mutation rather than gene amplification is associated with ETV1 expression in melanoma brain metastases

artículo científico publicado en 2014

MBCL-21. EARLY CHILDHOOD MEDULLOBLASTOMA: SUBGROUP-SPECIFIC SURVIVAL IN PATIENTS TREATED WITH SYSTEMIC CHEMOTHERAPY AND INTRAVENTRICULAR MTX TO AVOID CRANIOSPINAL RADIOTHERAPY

MGMT testing--the challenges for biomarker-based glioma treatment

artículo científico publicado en 2014

MMP-13 and p53 in the progression of malignant peripheral nerve sheath tumors

artículo científico publicado en 2007

MNGI-02. PREOPERATIVE EMBOLIZATION OF MENINGIOMA: INFERIOR NEUROLOGICAL OUTCOME, INCREASED RISK OF CARDIOVASCULAR COMPLICATIONS AND SHORTER TIME TO RECURRENCE?

MNGI-05. DEVELOPMENT AND VALIDATION OF A DNA METHYLOME-BASED PREDICTOR OF MENINGIOMA RECURRENCE AND MENINGIOMA RECURRENCE SCORE

artículo científico publicado en 2018

MNGI-13. A DNA METHYLATION-BASED CLASSIFIER FOR ASSESSMENT OF RISK OF RECURRENCE IN MENINGIOMA

MNGI-14. LOSS OF HISTONE H3K27me3 IDENTIFIES A SUBSET OF MENINGIOMAS WITH INCREASED RISK OF RECURRENCE

MNGI-28. CORRELATION OF METHYLATION CLASS AND GENETIC ALTERATIONS WITH PROGRESSION FREE SURVIVAL IN MENINGIOMA

artículo científico publicado en 2018

MOLECULAR GENETIC DETERMINANTS OF LONG-TERM SURVIVAL WITH GLIOBLASTOMA.

artículo científico publicado en 2014

MTS1/CDKN2 gene mutations are rare in primary human astrocytomas with allelic loss of chromosome 9p

scientific article published on 01 October 1994

MYCN amplification drives an aggressive form of spinal ependymoma

scientific article published on 14 August 2019

MYCN and HDAC5 transcriptionally repress CD9 to trigger invasion and metastasis in neuroblastoma

artículo científico publicado en 2016

MYCN transcriptionally represses CD9 to trigger an invasion-metastasis cascade in neuroblastoma

artículo científico publicado en 2015

Machine learning workflows to estimate class probabilities for precision cancer diagnostics on DNA methylation microarray data

scientific article published on 13 January 2020

Medulloblastoma harbor somatic mitochondrial DNA mutations in the D-loop region.

artículo científico publicado en 2010

Medulloblastomas of the desmoplastic variant carry mutations of the human homologue of Drosophila patched.

artículo científico publicado en 1997

Melanotic tumors of the nervous system are characterized by distinct mutational, chromosomal and epigenomic profiles

artículo científico publicado en 2014

Meningeal hemangiopericytoma and solitary fibrous tumors carry the NAB2-STAT6 fusion and can be diagnosed by nuclear expression of STAT6 protein

artículo científico publicado en 2013

Meningiomas induced by low-dose radiation carry structural variants of NF2 and a distinct mutational signature

artículo científico publicado en 2017

Methylation analysis of the neurofibromatosis type 1 (NF1) promoter in peripheral nerve sheath tumours.

artículo científico publicado en 2004

Methylation array profiling of adult brain tumours: diagnostic outcomes in a large, single centre

Methylation profiling of choroid plexus tumors reveals 3 clinically distinct subgroups

artículo científico publicado en 2016

Methylation-based classification of benign and malignant peripheral nerve sheath tumors

artículo científico publicado en 2016

Methylome analyses of three glioblastoma cohorts reveal chemotherapy sensitivity markers within DDR genes ⬇️

artículo científico publicado en 2020

Metronomic chemotherapy with daily low-dose temozolomide and celecoxib in elderly patients with newly diagnosed glioblastoma multiforme: a retrospective analysis

artículo científico publicado en 2015

Microscopic brain invasion in meningiomas previously classified as WHO grade I is not associated with patient outcome

artículo científico publicado en 2019

Molecular Classification of Ependymal Tumors across All CNS Compartments, Histopathological Grades, and Age Groups

artículo científico publicado en 2015

Molecular Diagnostics in Pediatric Brain Tumors: Impact on Diagnosis and Clinical Decision-Making - A Selected Case Series

scientific article published on 11 July 2018

Molecular Transition of an Adult Low-Grade Brain Tumor to an Atypical Teratoid/Rhabdoid Tumor Over a Time-Course of 14 Years

artículo científico

Molecular analysis of pediatric CNS-PNET revealed nosologic heterogeneity and potent diagnostic markers for CNS neuroblastoma with FOXR2-activation

artículo científico publicado en 2021

Molecular analysis of the TSC1 and TSC2 tumour suppressor genes in sporadic glial and glioneuronal tumours.

artículo científico publicado en 2000

Molecular and translational advances in meningiomas

scientific article published on 01 January 2019

Molecular characterization of CNS paragangliomas identifies cauda equina paragangliomas as a distinct tumor entity

artículo científico publicado en 2020

Molecular characterization of long-term survivors of glioblastoma using genome- and transcriptome-wide profiling.

artículo científico publicado en 2014

Molecular characterization of medulloblastomas with extensive nodularity (MBEN).

artículo científico publicado en 2018

Molecular classification of diffuse cerebral WHO grade II/III gliomas using genome- and transcriptome-wide profiling improves stratification of prognostically distinct patient groups

artículo científico publicado en 2015

Molecular differences in IDH wildtype glioblastoma according to MGMT promoter methylation.

artículo científico publicado en 2017

Molecular genetic analysis as a tool for evaluating stereotactic biopsies of glioma specimens.

artículo científico publicado en 1999

Molecular genetic analysis of ependymal tumors. NF2 mutations and chromosome 22q loss occur preferentially in intramedullary spinal ependymomas

artículo científico publicado en 1999

Molecular genetic analysis of giant cell glioblastomas ⬇️

artículo científico publicado el 1 de septiembre de 1997

Molecular genetic analysis of oligodendroglial tumors

artículo científico publicado en 2005

Molecular genetic evidence for subtypes of oligoastrocytomas.

artículo científico publicado en 1997

Molecular markers in low-grade gliomas: predictive or prognostic?

artículo científico publicado en 2011

Molecular pathogenesis of oligodendroglial tumors

artículo científico publicado en 2004

Molecular pathology of oligodendroglial tumors

artículo científico publicado en 2009

Molecular pathways in the formation of gliomas.

artículo científico publicado en 1995

Molecular predictors of progression-free and overall survival in patients with newly diagnosed glioblastoma: a prospective translational study of the German Glioma Network

artículo científico publicado en 2009

Molecular profiling of long-term survivors identifies a subgroup of glioblastoma characterized by chromosome 19/20 co-gain

artículo científico publicado en 2015

Molecular profiling-based decision for targeted therapies in IDH wild-type glioblastoma

artículo científico publicado en 2020

Molecular progression of SHH-activated medulloblastomas

scientific article published on 27 April 2019

Molecular signatures classify astrocytic gliomas by IDH1 mutation status.

artículo científico publicado en 2011

Molecular staging of intracranial ependymoma in children and adults

artículo científico publicado en 2010

Molecular subgrouping of primary pineal parenchymal tumors reveals distinct subtypes correlated with clinical parameters and genetic alterations

scientific article published on 25 November 2019

Molecularly defined diffuse leptomeningeal glioneuronal tumor (DLGNT) comprises two subgroups with distinct clinical and genetic features.

artículo científico publicado en 2018

Monoclonal antibody specific for IDH1 R132H mutation

artículo científico publicado en 2009

Morphologic and immunohistochemical features of malignant peripheral nerve sheath tumors and cellular schwannomas.

artículo científico publicado en 2014

Mosaic trisomy of chromosome 1q in human brain tissue associates with unilateral polymicrogyria, very early-onset focal epilepsy, and severe developmental delay

scientific article published on 26 September 2020

Multicenter Evaluation of a Novel Automated Rapid Detection System of BRAF Status in Formalin-Fixed, Paraffin-Embedded Tissues

artículo científico publicado en 2016

Multidimensional scaling of diffuse gliomas: application to the 2016 World Health Organization classification system with prognostically relevant molecular subtype discovery

artículo científico publicado en 2017

Multiple polymorphisms, but no mutations, in the WAF1/CIP1 gene in human brain tumours ⬇️

artículo científico publicado el 1 de noviembre de 1995

Mutant BRAF V600E protein in ganglioglioma is predominantly expressed by neuronal tumor cells

artículo científico publicado en 2013

Mutant IDH Sensitizes Gliomas to Endoplasmic Reticulum Stress and Triggers Apoptosis via miR-183-Mediated Inhibition of Semaphorin 3E

artículo científico publicado en 2019

Mutant IDH1R132H bears a mutation-specific CD4 T cell epitope suitable for vaccination of human CNS tumors

scholarly article by Theresa Schumacher et al published October 2014 in Journal of Neuroimmunology

Mutation analysis of DKK1 and in vivo evidence of predominant p53-independent DKK1 function in gliomas

artículo científico publicado en 2005

Mutation and expression of PDGFRA and KIT in malignant peripheral nerve sheath tumors, and its implications for imatinib sensitivity

artículo científico publicado en 2005

Mutation specific antibodies: tool or dinosaur?

artículo científico publicado en 2012

Mutation-specific IDH1 antibody differentiates oligodendrogliomas and oligoastrocytomas from other brain tumors with oligodendroglioma-like morphology.

artículo científico publicado en 2010

Mutational analysis of INI1 in sporadic human brain tumors

artículo científico publicado en 2001

Mutational patterns and regulatory networks in epigenetic subgroups of meningioma

artículo científico publicado en 2019

N2M2 (NOA20) phase I/II trial of molecularly matched targeted therapies plus radiotherapy in patients with newly diagnosed non-MGMT hypermethylated glioblastoma

artículo científico publicado en 2019

NDRG1 prognosticates the natural course of disease in WHO grade II glioma

artículo científico publicado en 2014

NEXT-GENERATION NEUROPATHOLOGY - IMPROVING DIAGNOSTIC ACCURACY FOR BRAIN TUMORS USING DNA METHYLATION ARRAY-BASED MOLECULAR PROFILING.

artículo científico publicado en 2014

NF2 mutations in secretory and other rare variants of meningiomas

artículo científico publicado en 2006

NIMG-30. PREOPERATIVE PREDICTORS OF MALIGNANCY IN NON-ENHANCING GLIOMA IN THE ERA OF MOLECULAR CLASSIFICATION

NIMG-51. RADIOLOGIC PHENOTYPES ARE TREATMENT SPECIFIC AND ASSOCIATED WITH SURVIVAL - EXPLORATORY ANALYSIS OF EORTC 26101

artículo científico publicado en 2017

NOA-04 randomized phase III trial of sequential radiochemotherapy of anaplastic glioma with procarbazine, lomustine, and vincristine or temozolomide

artículo científico publicado en 2009

Nbn and atm cooperate in a tissue and developmental stage-specific manner to prevent double strand breaks and apoptosis in developing brain and eye.

artículo científico publicado en 2013

Nestin expression identifies ependymoma patients with poor outcome

artículo científico publicado en 2012

Neurofibromatosis type 1: pathology, clinical features and molecular genetics.

artículo científico publicado en 1995

Neurofibromin C terminus-specific antibody (clone NFC) is a valuable tool for the identification of NF1-inactivated GISTs.

artículo científico publicado en 2017

Neurofibromin specific antibody differentiates malignant peripheral nerve sheath tumors (MPNST) from other spindle cell neoplasms

artículo científico publicado en 2014

Neuroradiology of central neurocytoma.

artículo científico publicado en 1991

New Brain Tumor Entities Emerge from Molecular Classification of CNS-PNETs

artículo científico publicado en 2016

Next-generation personalised medicine for high-risk paediatric cancer patients - The INFORM pilot study

artículo científico publicado en 2016

Next-generation sequencing in routine brain tumor diagnostics enables an integrated diagnosis and identifies actionable targets

artículo científico publicado en 2015

No ING1 mutations in human brain tumours but reduced expression in high malignancy grades of astrocytoma

artículo científico publicado en 2004

No evidence for BRAF-V600E mutations in gastroeosophageal tumors: results from a high-throughput analysis of 534 cases using a mutation-specific antibody

artículo científico publicado en 2013

No evidence of hSNF5/INI1 point mutations in choroid plexus papilloma.

artículo científico publicado en 2004

No preferential loss of paternal 19q alleles in oligodendroglial tumors

artículo científico publicado en 2003

No prognostic value of IDH1 mutations in a series of 100 WHO grade II astrocytomas

artículo científico publicado en 2012

Noninvasive Characterization of Tumor Angiogenesis and Oxygenation in Bevacizumab-treated Recurrent Glioblastoma by Using Dynamic Susceptibility MRI: Secondary Analysis of the European Organization for Research and Treatment of Cancer 26101 Trial

artículo científico publicado en 2020

Nonmeasurable Speckled Contrast-Enhancing Lesions Appearing During Course of Disease Are Associated With IDH Mutation in High-Grade Astrocytoma Patients

scientific article published on 31 July 2018

Nonmetastatic Medulloblastoma of Early Childhood: Results From the Prospective Clinical Trial HIT-2000 and An Extended Validation Cohort

scientific article published on 24 April 2020

Novel genomic amplification targeting the microRNA cluster at 19q13.42 in a pediatric embryonal tumor with abundant neuropil and true rosettes.

artículo científico publicado en 2008

Novel oncogene amplifications in tumors from a family with Li-Fraumeni syndrome

artículo científico publicado en 2009

Novel, improved grading system(s) for IDH-mutant astrocytic gliomas

artículo científico publicado en 2018

Nuclear relocation of STAT6 reliably predicts NAB2-STAT6 fusion for the diagnosis of solitary fibrous tumour

artículo científico publicado en 2014

O10.01PROGNOSTIC AND PREDICTIVE BIOMARKER-BASED SUBGROUPS IN THE NOA-04 TRIAL.

artículo científico publicado en 2014

O6.06PERIPHERAL T CELL RESPONSES IN GLIOBLASTOMA PATIENTS ARE ASSOCIATED WITH AN IMPROVED SURVIVAL.

artículo científico publicado en 2014

O6.09PROSTAGLANDIN E RECEPTOR-4 ACTIVATION REGULATES TRYPTOPHAN METABOLISM IN HUMAN MALIGNANT GLIOMAS.

artículo científico publicado en 2014

OMICS AND PROGNSTIC MARKERS

article

OS07.1 Molecular differences in IDH wild type glioblastoma according to MGMT promoter methylation status.

artículo científico publicado en 2017

OS6.1 Molecular characterization of astroblastoma.

artículo científico publicado en 2016

OS6.4 Molecular classification of meningiomas across all histological subtypes and grades.

artículo científico publicado en 2016

Occurrence of a spinal anaplastic pilocytic astrocytoma and a supratentorial PNET in an adolescent.

artículo científico publicado en 2007

Oligodendrogliomas: impact of molecular genetics on treatment.

artículo científico publicado en 2005

Oncogene complementation in fetal brain transplants ⬇️

artículo científico publicado el 1 de julio de 1992

Oncogenic FAM131B-BRAF fusion resulting from 7q34 deletion comprises an alternative mechanism of MAPK pathway activation in pilocytic astrocytoma

artículo científico publicado en 2011

Oncolytic H-1 Parvovirus Shows Safety and Signs of Immunogenic Activity in a First Phase I/IIa Glioblastoma Trial.

artículo científico publicado en 2017

Onconase induces caspase-independent cell death in chemoresistant neuroblastoma cells

artículo científico publicado en 2006

P02.03 Multiple sclerosis and gliomas - a coincidence?

artículo científico publicado en 2016

P04.22OLIGOASTROCYTOMA DOES NOT EXIST: A MOLECULAR GENETIC REAPPRAISAL ON SINGLE-CELL LEVEL.

artículo científico publicado en 2014

P06.06 A mutation-specific vaccine for Histone-3 K27M-mutated gliomas.

artículo científico publicado en 2017

P08.48 Combined alterations in MAPK pathway genes, CDKN2A/B and ATRX characterize anaplastic pilocytic astrocytoma.

artículo científico publicado en 2016

P08.76 Anti-EGFL7 treatment as an add-on for glioma therapy.

artículo científico publicado en 2016

P09.09 Gain of 12p encompassing CCND2 is associated with gemistocytic histology in IDH mutant astrocytomas.

artículo científico publicado en 2016

P09.18 Location-dependent prognostic factors and recurrence patterns in IDH wildtype glioblastoma.

artículo científico publicado en 2017

PATH-04. AN ENHANCED AI-DRIVEN PLATFORM FOR PRECISION MOLECULAR BRAIN TUMOR DIANOSTICS

publication published on 01 December 2020

PATH-24. MOLECULAR SUBGROUPS OF ADULT EPENDYMAL TUMORS: AN ANALYSIS OF THE GERMAN GLIOMA NETWORK

PCR- and restriction endonuclease-based detection of IDH1 mutations

artículo científico publicado en 2009

PDCT-05. MOLECULAR DIAGNOSTICS REVEAL 60% HIGHER SURVIVAL FOR MOLECULARLY-VERIFIED VERSUS HISTOPATHOLOGICALLY-DIAGNOSED PEDIATRIC SUPRATENTORIAL CENTRAL NERVOUS SYSTEM EMBRYONAL TUMORS AND PINEOBLASTOMAS; A REPORT FROM THE CHILDREN’S ONCOLOGY GROUP

PDTM-47. CHARACTERIZATION OF THE SENESCENCE-ASSOCIATED SECRETORY PHENOTYPE IN PILOCYTIC ASTROCYTOMA AND ITS ROLE IN ONCOGENE-INDUCED SENESCENCE

PIK3CA mutations in glioblastoma multiforme

artículo científico publicado en 2005

PIK3CA mutations in oligodendroglial tumours.

artículo científico publicado en 2006

PROGNOSTIC AND PREDICTIVE BIOMARKER-BASED SUBGROUPS IN THE NOA-04 TRIAL.

artículo científico publicado en 2014

PROX1 is a predictor of survival for gliomas WHO grade II

artículo científico publicado en 2011

PTEN mutations in gliomas and glioneuronal tumors.

artículo científico publicado en 1998

Pan-Mutant-IDH1 Inhibitor Bay-1436032 Is Highly Effective Against Human IDH1 Mutant Acute Myeloid Leukemia In Vivo ⬇️

scholarly article

Pan-mutant IDH1 inhibitor BAY 1436032 for effective treatment of IDH1 mutant astrocytoma in vivo

artículo científico publicado en 2017

Pan-mutant-IDH1 inhibitor BAY1436032 is highly effective against human IDH1 mutant acute myeloid leukemia in vivo.

artículo científico publicado en 2017

Papillary Tumor of the Pineal Region: A Distinct Molecular Entity

artículo científico publicado en 2015

Papillary glioneuronal tumor (PGNT) exhibits a characteristic methylation profile and fusions involving PRKCA

artículo científico publicado en 2019

Pathology and molecular genetics of oligodendroglial tumors

artículo científico publicado en 2004

Patients with IDH1 wild type anaplastic astrocytomas exhibit worse prognosis than IDH1-mutated glioblastomas, and IDH1 mutation status accounts for the unfavorable prognostic effect of higher age: implications for classification of gliomas

artículo científico publicado en 2010

Patients with high-grade gliomas harboring deletions of chromosomes 9p and 10q benefit from temozolomide treatment

artículo científico publicado en 2005

Patterns of differentiation in central neurocytoma. An immunohistochemical study of eleven biopsies

artículo científico publicado en 1990

Pdgfr-alpha in 1p/19q LOH oligodendrogliomas.

artículo científico publicado en 2004

Pediatric Targeted Therapy: Clinical Feasibility of Personalized Diagnostics in Children with Relapsed and Progressive Tumors

artículo científico publicado en 2015

Pilocytic astrocytoma presenting as primary diffuse leptomeningeal gliomatosis: report of a unique case and review of the literature.

artículo científico publicado en 2005

Post-mortem studies in glioblastoma patients treated with thermotherapy using magnetic nanoparticles.

artículo científico publicado en 2008

Post-operative cardiovascular complications and time to recurrence in meningioma patients treated with versus without pre-operative embolization: a retrospective cohort study of 741 patients

artículo científico publicado en 2018

Posterior fossa pilocytic astrocytomas with oligodendroglial features show frequent FGFR1 activation via fusion or mutation

artículo científico publicado en 2019

Practical implementation of DNA methylation and copy-number-based CNS tumor diagnostics: the Heidelberg experience.

artículo científico publicado en 2018

Predicting chemoresistance in human malignant glioma cells: the role of molecular genetic analyses.

artículo científico publicado en 1998

Predictive molecular markers in metastases to the central nervous system: recent advances and future avenues

artículo científico

Presence of alternative lengthening of telomeres mechanism in patients with glioblastoma identifies a less aggressive tumor type with longer survival.

artículo científico publicado en 2010

Presence of an oligodendroglioma-like component in newly diagnosed glioblastoma identifies a pathogenetically heterogeneous subgroup and lacks prognostic value: central pathology review of the EORTC_26981/NCIC_CE.3 trial

artículo científico

Pretreatment d-2-hydroxyglutarate serum levels negatively impact on outcome in IDH1-mutated acute myeloid leukemia.

artículo científico publicado en 2015

Primary CNS Alveolar Rhabdomyosarcoma: Importance of Epigenetic and Transcriptomic Assays for Accurate Diagnosis

scientific article published on 01 November 2019

Primary T-cell lymphoma of the central nervous system.

artículo científico publicado en 1990

Primary intracranial sarcomas with DICER1 mutation often contain prominent eosinophilic cytoplasmic globules and can occur in the setting of neurofibromatosis type 1

scientific article published on 16 January 2019

Primary intracranial spindle cell sarcoma with rhabdomyosarcoma-like features share a highly distinct methylation profile and DICER1 mutations.

artículo científico publicado en 2018

Primary mismatch repair deficient IDH-mutant astrocytoma (PMMRDIA) is a distinct type with a poor prognosis

scientific article published on 20 November 2020

Printed peptide arrays identify prognostic TNC serumantibodies in glioblastoma patients

artículo científico publicado en 2015

Prognostic but not predictive role of platelet-derived growth factor receptors in patients with recurrent glioblastoma

artículo científico publicado en 2011

Prognostic factors and long-term survival in surgically treated brain metastases from non-small cell lung cancer

artículo científico publicado en 2016

Prognostic or predictive value of MGMT promoter methylation in gliomas depends on IDH1 mutation

artículo científico publicado en 2013

Prognostic relevance of FDG PET in patients with neurofibromatosis type-1 and malignant peripheral nerve sheath tumours

artículo científico publicado en 2006

Prognostic relevance of miRNA-155 methylation in anaplastic glioma

artículo científico publicado en 2016

Prognostic role of Epidermal growth factor receptor variant III (EGFRvIII) positivity in EGFR-amplified primary and recurrent glioblastomas

artículo científico

Prognostic significance of IDH-1 and MGMT in patients with glioblastoma: one step forward, and one step back?

artículo científico publicado en 2011

Prognostic stratification of gliomatosis cerebri by IDH1 R132H and INA expression

artículo científico publicado en 2011

Prognostic value of the extent of resection in supratentorial WHO grade II astrocytomas stratified for IDH1 mutation status: a single-center volumetric analysis

artículo científico publicado en 2016

Prognostic value of three different methods of MGMT promoter methylation analysis in a prospective trial on newly diagnosed glioblastoma

artículo científico publicado en 2012

Promotion of glioblastoma cell motility by enhancer of zeste homolog 2 (EZH2) is mediated by AXL receptor kinase

artículo científico publicado en 2012

Protein kinase Cβ as a therapeutic target stabilizing blood-brain barrier disruption in experimental autoimmune encephalomyelitis

artículo científico publicado en 2013

Proteomics in pathology

artículo científico publicado en 2017

Proximity ligation assay evaluates IDH1R132H presentation in gliomas

artículo científico publicado en 2015

Publisher Correction: Actively personalized vaccination trial for newly diagnosed glioblastoma

scientific article published on 01 February 2019

Quality assurance in neuropathology: Experiences from the round robin trials on IDH mutation and MGMT promoter methylation testing launched by the Quality Assurance Initiative Pathology (QuIP) in 2018 and 2019

scientific article published on 30 April 2020

Quantitative analysis of neurofibromatosis type 2 gene transcripts in meningiomas supports the concept of distinct molecular variants

artículo científico publicado en 1997

Quercetin promotes degradation of survivin and thereby enhances death-receptor-mediated apoptosis in glioma cells

artículo científico publicado en 2008

R132H-mutation of isocitrate dehydrogenase-1 is not sufficient for HIF-1α upregulation in adult glioma.

artículo científico publicado en 2010

RASSF1A, BLU, NORE1A, PTEN and MGMT expression and promoter methylation in gliomas and glioma cell lines and evidence of deregulated expression of de novo DNMTs.

artículo científico publicado en 2008

RESULTS OF THE INTERNATIONAL INTERLABORATORY COMPARISON OF MGMT PROMOTER METHYLATION ANALYSIS INVOLVING TWENTY-THREE ACADEMIC CENTERS IN GERMANY, AUSTRIA AND THE NETHERLANDS.

artículo científico publicado en 2014

RINT1 functions as a multitasking protein at the crossroads between genomic stability, ER homeostasis, and autophagy

artículo científico publicado en 2016

Radiation-induced gliomas represent H3-/IDH-wild type pediatric gliomas with recurrent PDGFRA amplification and loss of CDKN2A/B

artículo científico publicado en 2021

Radiogenomic rCBV-imaging visualizes the moleculare signature of IDH-mutant and wildtype gliomas

Radiogenomics of Glioblastoma: Machine Learning-based Classification of Molecular Characteristics by Using Multiparametric and Multiregional MR Imaging Features

artículo científico publicado en 2016

Radiomic subtyping improves disease stratification beyond key molecular, clinical and standard imaging characteristics in patients with glioblastoma

artículo científico publicado en 2017

Radiotherapy plus concomitant temozolomide in primary gliosarcoma

artículo científico publicado en 2016

Rapid detection of 2-hydroxyglutarate in frozen sections of IDH mutant tumors by MALDI-TOF mass spectrometry.

artículo científico publicado en 2018

Rare mutations of the DMBT1 gene in human astrocytic gliomas

artículo científico publicado en 2002

Recurrent fusions in PLAGL1 define a distinct subset of pediatric-type supratentorial neuroepithelial tumors

artículo científico publicado en 2021

Recurrent somatic alterations of FGFR1 and NTRK2 in pilocytic astrocytoma

artículo científico publicado en 2013

Reduced H3K27me3 and DNA hypomethylation are major drivers of gene expression in K27M mutant pediatric high-grade gliomas

artículo científico publicado en 2013

Refined deletion mapping of the chromosome 19q glioma tumor suppressor gene to the D19S412-STD interval.

artículo científico publicado en 1996

Repeat surgery of recurrent glioma for molecularly informed treatment in the age of precision oncology: A risk–benefit analysis

artículo científico publicado en 2024

Reply to J.C. Lindsey et al

Report of a Novel Case of Anaplastic Olfactory Groove Meningioma and Its Methylation Subtype

artículo científico publicado en 2017

Retinoid resistance and multifaceted impairment of retinoic acid synthesis in glioblastoma

artículo científico publicado en 2015

Reversal of P-glycoprotein-mediated multidrug resistance by the murine double minute 2 antagonist nutlin-3.

artículo científico publicado en 2009

RhoA regulates translation of the Nogo-A decoy SPARC in white matter-invading glioblastomas

scientific article published on 06 May 2019

Rint1 inactivation triggers genomic instability, ER stress and autophagy inhibition in the brain.

artículo científico publicado en 2015

Role of LIM and SH3 protein 1 (LASP1) in the metastatic dissemination of medulloblastoma

artículo científico publicado en 2010

Role of genomic instability in meningioma progression

artículo científico publicado en 1996

Rosette-forming glioneuronal tumors share a distinct DNA methylation profile and mutations in FGFR1, with recurrent co-mutation of PIK3CA and NF1

scientific article published on 27 June 2019

Routine RNA sequencing of formalin-fixed paraffin-embedded specimens in neuropathology diagnostics identifies diagnostically and therapeutically relevant gene fusions

scientific article published on 05 July 2019

SPONTANEOUS IMMUNE RESPONSES IN GBM PATIENTS AFTER COMPLETE TUMOR RESECTION ARE ASSOCIATED WITH AN IMPROVED SURVIVAL.

artículo científico publicado en 2014

SURG-16PROGNOSTIC VALUE OF THE EXTENT OF RESECTION AND IDH1 MUTATION STATUS IN WHO GRADE II ASTROCYTOMAS.

artículo científico publicado en 2015

Sarcoma classification by DNA methylation profiling

artículo científico publicado en 2021

Sclerosing epithelioid mesenchymal neoplasm of the pancreas - a proposed new entity

artículo científico publicado en 2019

Secondary anaplastic astrocytoma developing in a young adult with autoimmune lymphoproliferative syndrome (ALPS).

artículo científico publicado en 2011

Secretory meningiomas are defined by combined KLF4 K409Q and TRAF7 mutations

artículo científico publicado en 2013

Selective inhibition of HDAC8 decreases neuroblastoma growth in vitro and in vivo and enhances retinoic acid-mediated differentiation

artículo científico publicado en 2015

Sensitivity of human meningioma cells to the cyclin-dependent kinase inhibitor, TG02

scientific article published on 08 September 2020

Sensitivity of malignant peripheral nerve sheath tumor cells to TRAIL is augmented by loss of NF1 through modulation of MYC/MAD and is potentiated by curcumin through induction of ROS.

artículo científico publicado en 2013

Single-nucleus chromatin accessibility reveals intratumoral epigenetic heterogeneity in IDH1 mutant gliomas

scientific article published on 05 December 2019

Somatic mitochondrial mutations in pilocytic astrocytoma.

artículo científico publicado en 2009

Somatic mutations in peroxisome proliferator-activated receptor-gamma are rare events in human cancer cells.

artículo científico publicado en 2004

Somatic mutations of DICER1 and KMT2D are frequent in intraocular medulloepitheliomas

artículo científico publicado en 2016

Spatial transcriptome analysis reveals Notch pathway-associated prognostic markers in IDH1 wild-type glioblastoma involving the subventricular zone

artículo científico publicado en 2016

Stem-cell-like glioma cells are resistant to TRAIL/Apo2L and exhibit down-regulation of caspase-8 by promoter methylation

artículo científico publicado en 2009

Stepwise accumulation of distinct genomic aberrations in a patient with progressively metastasizing ependymoma

artículo científico publicado en 2009

Subclassification of nerve sheath tumors by gene expression profiling

artículo científico publicado en 2004

Superiority of temozolomide over radiotherapy for elderly patients with RTK II methylation class, MGMT promoter-methylated malignant astrocytoma

scientific article published on 17 February 2020

Suppression of TDO-mediated tryptophan catabolism in glioblastoma cells by a steroid-responsive FKBP52-dependent pathway

artículo científico publicado en 2014

Suppression of antitumor T cell immunity by the oncometabolite (R)-2-hydroxyglutarate

scientific article published on 09 July 2018

Surfactant Expression Defines an Inflamed Subtype of Lung Adenocarcinoma Brain Metastases that Correlates with Prolonged Survival

artículo científico publicado en 2020

Survival according to BRAF-V600 tumor mutations--an analysis of 437 patients with primary melanoma

artículo científico publicado en 2014

Systematic analysis of RNA-binding proteins identifies targetable therapeutic vulnerabilities in osteosarcoma

artículo científico publicado en 2024

T2/FLAIR-mismatch sign for noninvasive detection of IDH-mutant 1p/19q non-codeleted gliomas: validity and pathophysiology

artículo científico publicado en 2020

TB-11MOLECULAR NEUROPATHOLOGY 2.0 - INCREASING DIAGNOSTIC ACCURACY IN PEDIATRIC NEUROONCOLOGY.

artículo científico publicado en 2016

TB-14THE INFORM PERSONALIZED MEDICINE STUDY - NEW MOLECULAR INSIGHTS INTO RELAPSED PEDIATRIC BRAIN TUMORS.

artículo científico publicado en 2016

TBIO-07. ASSESSING THE UTILITY OF DNA METHYLATION PROFILING IN BRAIN TUMOR DIAGNOSTICS—THE PROSPECTIVE MNP2.0 STUDY

TBIO-10. PEDIATRIC TARGETED THERAPY 2.0: DEVELOPMENT OF PERSONALIZED PEDIATRIC ONCOLOGY

TERT Promoter Mutations and Risk of Recurrence in Meningioma

artículo científico publicado en 2015

TERT promoter hotspot mutations are recurrent in myxoid liposarcomas but rare in other soft tissue sarcoma entities

artículo científico publicado en 2014

TERT promoter mutations are highly recurrent in SHH subgroup medulloblastoma

artículo científico publicado en 2013

TP53 gene mutations, nuclear p53 accumulation, expression of Waf/p21, Bcl-2, and CD95 (APO-1/Fas) proteins are not prognostic factors in de novo glioblastoma multiforme

scientific article published on 01 May 2001

TP53 mutation is frequently associated with CTNNB1 mutation or MYCN amplification and is compatible with long-term survival in medulloblastoma.

artículo científico publicado en 2010

TRTH-09. PTT2.0: DEVELOPING PERSONALIZED PEDIATRIC ONCOLOGY.

artículo científico publicado en 2017

TUMOUR BIOLOGY

Targetable ERBB2 mutations identified in neurofibroma/schwannoma hybrid nerve sheath tumors

scientific article published on 04 February 2020

Targeted Genomic Profiling of Acral Melanoma

scientific article published on 01 October 2019

Targeting class I histone deacetylase 2 in MYC amplified group 3 medulloblastoma

artículo científico publicado en 2015

Targeting resistance against the MDM2 inhibitor RG7388 in glioblastoma cells by the MEK inhibitor trametinib

artículo científico publicado en 2018

Targeting the BRAF V600E mutation in multiple myeloma

artículo científico publicado en 2013

Temozolomide chemotherapy versus radiotherapy in high-risk low-grade glioma (EORTC 22033-26033): a randomised, open-label, phase 3 intergroup study

artículo científico publicado en 2016

Testing of SNS-032 in a Panel of Human Neuroblastoma Cell Lines with Acquired Resistance to a Broad Range of Drugs

artículo científico publicado en 2013

The 2016 World Health Organization Classification of Tumors of the Central Nervous System: a summary

artículo científico publicado en 2016

The 4q12 amplicon in malignant peripheral nerve sheath tumors: consequences on gene expression and implications for sunitinib treatment

artículo científico publicado en 2010

The APC gene in Turcot's syndrome.

artículo científico publicado en 1995

The BAX gene maps to the glioma candidate region at 19q13.3, but is not altered in human gliomas.

artículo científico publicado en 1996

The Cancer Genome Atlas Comprehensive Molecular Characterization of Renal Cell Carcinoma

article

The DNA methylome of DDR genes and benefit from RT or TMZ in IDH mutant low-grade glioma treated in EORTC 22033.

artículo científico publicado en 2018

The SRCR/SID region of DMBT1 defines a complex multi-allele system representing the major basis for its variability in cancer

artículo científico publicado en 2002

The Senescence-associated Secretory Phenotype Mediates Oncogene-induced Senescence in Pediatric Pilocytic Astrocytoma

artículo científico publicado en 2018

The Wnt secretion protein Evi/Gpr177 promotes glioma tumourigenesis

artículo científico publicado en 2011

The current consensus on the clinical management of intracranial ependymoma and its distinct molecular variants

artículo científico publicado en 2016

The effect of thermotherapy using magnetic nanoparticles on rat malignant glioma

artículo científico publicado en 2005

The efficacy of bipolar and multipolar radiofrequency ablation of lung neoplasms - results of an ablate and resect study

scientific article published on 18 October 2010

The endogenous tryptophan metabolite and NAD+ precursor quinolinic acid confers resistance of gliomas to oxidative stress

artículo científico publicado en 2013

The epidermal growth factor receptor in glioblastoma: genomic amplification, protein expression, and patient survival data in a therapeutic trial.

artículo científico publicado en 1995

The evolution of our understanding on glioma

artículo científico publicado en 2008

The flavonoid kaempferol sensitizes human glioma cells to TRAIL-mediated apoptosis by proteasomal degradation of survivin

artículo científico publicado en 2008

The inhibitor of growth 1 (ING1) is involved in trichostatin A-induced apoptosis and caspase 3 signaling in p53-deficient glioblastoma cells

artículo científico publicado en 2010

The inhibitor of growth 1 (ING1) proteins suppress angiogenesis and differentially regulate angiopoietin expression in glioblastoma cells

artículo científico publicado en 2009

The miR-139-5p regulates proliferation of supratentorial paediatric low-grade gliomas by targeting the PI3K/AKT/mTORC1 signalling

artículo científico publicado en 2018

The molecular evolution of glioblastoma treated by gross total resection alone

artículo científico publicado en 2020

The molecular landscape of ETMR at diagnosis and relapse

scientific article published on 04 December 2019

The next generation of glioma biomarkers: MGMT methylation, BRAF fusions and IDH1 mutations

artículo científico publicado en 2011

The p53 tumor suppressor is stabilized by inhibitor of growth 1 (ING1) by blocking polyubiquitination

artículo científico publicado en 2011

The retinoblastoma gene is involved in malignant progression of astrocytomas

artículo científico publicado en 1994

The transcription factor Ets-1 is expressed in human amniochorionic membranes and is up-regulated in term and preterm premature rupture of membranes

artículo científico publicado en 2005

The whole-genome landscape of medulloblastoma subtypes

artículo científico publicado en 2017

Therapeutic radiation for childhood cancer drives structural aberrations of NF2 in meningiomas

artículo científico publicado en 2017

Transcription factor AP-2 is expressed in human Schwann cell-derived tumours

artículo científico publicado en 2006

Transcriptional profiling of medulloblastoma with extensive nodularity (MBEN) reveals two clinically relevant tumor subsets with VSNL1 as potent prognostic marker

scientific article published on 28 November 2019

Transcriptomic analysis of aggressive meningiomas identifies PTTG1 and LEPR as prognostic biomarkers independent of WHO grade

artículo científico publicado en 2016

Transcriptomic and epigenetic dissection of spinal ependymoma (SP-EPN) identifies clinically relevant subtypes enriched for tumors with and without NF2 mutation

scholarly article

Tryptophan metabolism is inversely regulated in the tumor and blood of patients with glioblastoma

artículo científico publicado en 2021

Tryptophan-2,3-dioxygenase is regulated by prostaglandin E2 in malignant glioma via a positive signaling loop involving prostaglandin E receptor-4.

artículo científico publicado en 2015

Tumor cell plasticity, heterogeneity, and resistance in crucial microenvironmental niches in glioma

artículo científico publicado en 2021

Tumors diagnosed as cerebellar glioblastoma comprise distinct molecular entities

artículo científico publicado en 2019

Tweety-Homolog 1 Drives Brain Colonization of Gliomas.

artículo científico

Two molecularly distinct atypical teratoid/rhabdoid tumors (or tumor components) occurring in an infant with rhabdoid tumor predisposition syndrome 1

artículo científico publicado en 2019

Type and frequency of IDH1 and IDH2 mutations are related to astrocytic and oligodendroglial differentiation and age: a study of 1,010 diffuse gliomas.

artículo científico publicado en 2009

Type and frequency of p53 mutations in tumors of the nervous system and its coverings.

artículo científico publicado en 1994

Use of telomerase promoter mutations to mark specific molecular subsets with reciprocal clinical behavior in IDH mutant and IDH wild-type diffuse gliomas.

artículo científico publicado en 2017

Utilization of a MAB for BRAF(V600E) detection in papillary thyroid carcinoma.

artículo científico publicado en 2012

VXM01 phase I study in patients with progressive glioblastoma: Final results

Validation of a Manual Protocol for BRAF V600E Mutation-specific Immunohistochemistry

artículo científico publicado en 2015

Validation of diffusion MRI phenotypes for predicting response to bevacizumab in recurrent glioblastoma: post-hoc analysis of the EORTC-26101 trial

scientific article published on 11 May 2020

Voxel-wise radiogenomic mapping of tumor location with key molecular alterations in patients with glioma

artículo científico publicado en 2018

Whole exome sequencing reveals that the majority of schwannomatosis cases remain unexplained after excluding SMARCB1 and LZTR1 germline variants

article published in 2014

Withdrawal: Identification of tumor antigens among the HLA peptidomes of glioblastoma tumors and plasma

artículo científico publicado en 2019

YAP1-fusions in pediatric NF2-wildtype meningioma

artículo científico publicado en 2019

Yes and PI3K bind CD95 to signal invasion of glioblastoma

artículo científico publicado en 2008

[Induction of primitive neuroectodermal tumors by oncogene complementation]

artículo científico publicado en 1990

[Solid craniopharyngioma in the 3rd ventricle--differential diagnostic aspects]

artículo científico publicado en 1998

cIMPACT-NOW (the consortium to inform molecular and practical approaches to CNS tumor taxonomy): a new initiative in advancing nervous system tumor classification

artículo científico publicado en 2016

cIMPACT-NOW update 3: recommended diagnostic criteria for "Diffuse astrocytic glioma, IDH-wildtype, with molecular features of glioblastoma, WHO grade IV"

artículo científico publicado en 2018

cIMPACT-NOW update 5: recommended grading criteria and terminologies for IDH-mutant astrocytomas

scientific article published on 29 January 2020

cIMPACT-NOW update 6: new entity and diagnostic principle recommendations of the cIMPACT-Utrecht meeting on future CNS tumor classification and grading

artículo científico publicado en 2020

cIMPACT-NOW: a practical summary of diagnostic points from Round 1 updates

scientific article published on 22 May 2019

mIDH-associated DNA hypermethylation in acute myeloid leukemia reflects differentiation blockage rather than inhibition of TET-mediated demethylation

artículo científico publicado en 2017

mTOR target NDRG1 confers MGMT-dependent resistance to alkylating chemotherapy

artículo científico publicado en 2013

Lista de obras de Andreas von Deimling

2-Hydroxyglutarate concentration in serum from patients with gliomas does not correlate with IDH1/2 mutation status or tumor size

45-year-old male with symptomatic mass in the frontal lobe

A (CA)n dinucleotide repeat assay for evaluating loss of allelic heterozygosity in small and archival human brain tumor specimens.

A PRDX1-p38α heterodimer amplifies MET-driven invasion of IDH-wildtype and IDH-mutant gliomas

A device for processing large acrylamide gels.

A highly conserved processed PTEN pseudogene is located on chromosome band 9p21 ⬇️

A new approach to the molecular basis of neoplastic transformation in the brain

A new clinico-pathological classification system for mesial temporal sclerosis

A novel human high-risk ependymoma stem cell model reveals the differentiation-inducing potential of the histone deacetylase inhibitor Vorinostat

A novel, diffusely infiltrative xenograft model of human anaplastic oligodendroglioma with mutations in FUBP1, CIC, and IDH1.

A phase II, randomized, study of weekly APG101+reirradiation versus reirradiation in progressive glioblastoma

A polymerase chain reaction-based assay for the rapid detection of gene amplification in human tumors

A rapid and sensitive protocol for competitive reverse transcriptase (cRT) PCR analysis of cellular genes.

A role for beta-melanocyte-stimulating hormone in human body-weight regulation

A subset of pediatric-type thalamic gliomas share a distinct DNA methylation profile, H3K27me3 loss and frequent alteration of EGFR

A vaccine targeting mutant IDH1 induces antitumour immunity

ACTR-05. THE RANDOMIZED PHASE II ARTE TRIAL: BEVACIZUMAB PLUS HYPOFRACTIONATED RADIOTHERAPY VERSUS RADIOTHERAPY ALONE IN ELDERLY PATIENTS WITH NEWLY DIAGNOSED GLIOBLASTOMA.

ACTR-61. LONG-TERM ANALYSES OF THE NOA-08 RANDOMIZED PHASE III TRIAL

AKT1E17K mutations cluster with meningothelial and transitional meningiomas and can be detected by SFRP1 immunohistochemistry

ALK gene translocations and amplifications in brain metastases of non-small cell lung cancer.

ANGI-08RADIOGENOMIC rCBV-IMAGING VISUALIZES THE DISTINCT ANGIOGENESIS TRANSCRIPTOME SIGNATURES OF IDH MUTANT AND WILD-TYPE GLIOMAS.

ATIM-20. GAPVAC-101 TRIAL OF A HIGHLY PERSONALIZED PEPTIDE VACCINATION FOR PATIENTS WITH NEWLY DIAGNOSED GLIOBLASTOMA

ATIM-33. NOA-16: A FIRST-IN-MAN MULTICENTER PHASE I CLINICAL TRIAL OF THE GERMAN NEUROONCOLOGY WORKING GROUP EVALUATING A MUTATION-SPECIFIC PEPTIDE VACCINE TARGETING IDH1R132H IN PATIENTS WITH NEWLY DIAGNOSED MALIGNANT ASTROCYTOMAS

ATIM-35. VXM01 PHASE I STUDY IN PATIENTS WITH PROGRESSIVE GLIOBLASTOMA – FINAL RESULTS

ATRX and IDH1-R132H immunohistochemistry with subsequent copy number analysis and IDH sequencing as a basis for an "integrated" diagnostic approach for adult astrocytoma, oligodendroglioma and glioblastoma

ATRX loss refines the classification of anaplastic gliomas and identifies a subgroup of IDH mutant astrocytic tumors with better prognosis

Aberrant self-renewal and quiescence contribute to the aggressiveness of glioblastoma

Absence of immunoglobulin class switch in primary lymphomas of the central nervous system

Abstract 2182: Preclincial in vitro and in vivo combination therapies for mutant IDH1R132 tumors with BAY 1436032

Abstract 3094: Epigenetic classification of ependymal brain tumors across age groups

Abstract 4736: N-myc downstream regulated gene 1: A novel mediator of hypoxia-driven chemoresistance in glioblastoma

Abstracts

Abstracts of the 10th Congress of the European Association of NeuroOncology. Marseille, France. September 6-9, 2012

Accumulation of genomic aberrations during clinical progression of medulloblastoma

Accumulation of wild type p53 protein in human astrocytomas

Accurate calling of KIAA1549-BRAF fusions from DNA of human brain tumours using methylation array-based copy number and gene panel sequencing data

Actively personalized vaccination trial for newly diagnosed glioblastoma

Adamantinomatous and papillary craniopharyngiomas are characterized by distinct epigenomic as well as mutational and transcriptomic profiles

Adaptation of cancer cells from different entities to the MDM2 inhibitor nutlin-3 results in the emergence of p53-mutated multi-drug-resistant cancer cells.

Addressing diffuse glioma as a systemic brain disease with single-cell analysis

Adult IDH wild type astrocytomas biologically and clinically resolve into other tumor entities

Adult and pediatric medulloblastomas are genetically distinct and require different algorithms for molecular risk stratification

Adult medulloblastoma comprises three major molecular variants.

Aggressive Hematopoietic Malignancy Characterized by Biallelic Loss of SMARCB1

Allelic losses on chromosomes 14, 10, and 1 in atypical and malignant meningiomas: a genetic model of meningioma progression

Alterations in molecular pathways of diffusely infiltrating glial neoplasms: application to tumor classification and anti-tumor therapy (Review).

Alterations of cell cycle regulators in gliomatosis cerebri

Amplification and overexpression of CMET is a common event in brain metastases of non-small cell lung cancer

Amplification of the PLAG-family genes-PLAGL1 and PLAGL2-is a key feature of the novel tumor type CNS embryonal tumor with PLAGL amplification

Amplification of the cyclin-dependent kinase 4 (CDK4) gene is associated with high cdk4 protein levels in glioblastoma multiforme.

An endogenous tumour-promoting ligand of the human aryl hydrocarbon receptor

An optimized protocol for mRNA quantification using nested competitive RT-PCR

An optimized workflow to improve reliability of detection of KIAA1549:BRAF fusions from RNA sequencing data

Analysis of BRAF V600E mutation in 1,320 nervous system tumors reveals high mutation frequencies in pleomorphic xanthoastrocytoma, ganglioglioma and extra-cerebellar pilocytic astrocytoma

Analysis of CIC-associated CpG island methylation in oligoastrocytoma.

Analysis of IDH mutation, 1p/19q deletion, and PTEN loss delineates prognosis in clinical low-grade diffuse gliomas

Analysis of TP53 and PTEN in gliomatosis cerebri

Analysis of a Surgical Series of 21 Cerebral Radiation Necroses

Analysis of the IDH1 codon 132 mutation in brain tumors

Analysis of the MEN1 gene in sporadic pituitary adenomas

Analysis of the PTEN gene in human meningiomas

Analysis of the RET, GDNF, EDN3, and EDNRB genes in patients with intestinal neuronal dysplasia and Hirschsprung disease.

Anaplastic astrocytoma with piloid features, a novel molecular class of IDH wildtype glioma with recurrent MAPK pathway, CDKN2A/B and ATRX alterations

Announcing cIMPACT-NOW: the Consortium to Inform Molecular and Practical Approaches to CNS Tumor Taxonomy

Application of a BRAF V600E mutation-specific antibody for the diagnosis of hairy cell leukemia

Application of mutant IDH1 antibody to differentiate diffuse glioma from nonneoplastic central nervous system lesions and therapy-induced changes

Array-based DNA-methylation profiling in sarcomas with small blue round cell histology provides valuable diagnostic information

Assessment and prognostic significance of the epidermal growth factor receptor vIII mutation in glioblastoma patients treated with concurrent and adjuvant temozolomide radiochemotherapy

Assessment of BRAF V600E mutation status by immunohistochemistry with a mutation-specific monoclonal antibody

Assessment of Melanin Content and its Influence on Susceptibility Contrast in Melanoma Metastases

Assessment of tumor cell invasion factors in gliomatosis cerebri

Association Between Tumor Compartment Volumes, the Incidence of Pretreatment Seizures, and Statin-Mediated Protective Effects in Glioblastoma

Association between fluorine-18-labeled fluorodeoxyglucose uptake and 1p and 19q loss of heterozygosity in World Health Organization Grade II gliomas.

Association of EGFR Gene Amplification and CDKN2 (p16/MTS1) Gene Deletion in Glioblastoma Multiforme ⬇️

Association of allelic losses on human chromosomal arms 11q and 16q in sporadic breast cancer

Association of epidermal growth factor receptor gene amplification with loss of chromosome 10 in human glioblastoma multiforme

Association of loss of heterozygosity on chromosome 17p with high platelet-derived growth factor alpha receptor expression in human malignant gliomas.

Astrocytic gliomas: characterization on a molecular genetic basis.

Atypical Teratoid/Rhabdoid Tumors Are Comprised of Three Epigenetic Subgroups with Distinct Enhancer Landscapes