Lista de obras - Lars-Oliver Klotz - Dominio Público Uruguay

(-)-Epicatechin inhibits nitration and dimerization of tyrosine in hydrophilic as well as hydrophobic environments

artículo científico publicado en 2001

1,4-Naphthoquinones as inducers of oxidative damage and stress signaling in HaCaT human keratinocytes.

artículo científico publicado en 2010

1,4-naphthoquinones: from oxidative damage to cellular and inter-cellular signaling

artículo científico publicado en 2014

2-Methyl-1,4-naphthoquinone, vitamin K(3), decreases gap-junctional intercellular communication via activation of the epidermal growth factor receptor/extracellular signal-regulated kinase cascade.

artículo científico publicado en 2002

A Caenorhabditis elegans ortholog of human selenium-binding protein 1 is a pro-aging factor protecting against selenite toxicity

artículo científico publicado en 2019

Activation of ErbB2 by 2-methyl-1,4-naphthoquinone (menadione) in human keratinocytes: role of EGFR and protein tyrosine phosphatases

artículo científico publicado en 2006

Activation of JNK and p38 but not ERK MAP kinases in human skin cells by 5-aminolevulinate-photodynamic therapy

artículo científico publicado en 1998

Activation pattern of mitogen-activated protein kinases elicited by peroxynitrite: attenuation by selenite supplementation

artículo científico publicado en 1999

Acute and long-term effects of arsenite in HepG2 cells: modulation of insulin signaling

artículo científico publicado en 2014

Amphiphilic properties of (-)-epicatechin and their significance for protection of cells against peroxynitrite

artículo científico publicado en 2003

Arsenite-induced stress signaling: modulation of the phosphoinositide 3'-kinase/Akt/FoxO signaling cascade

artículo científico publicado en 2013

Cellular adaptation to xenobiotics: Interplay between xenosensors, reactive oxygen species and FOXO transcription factors

artículo científico publicado en 2017

Central role of Ferrous/Ferric iron in the ultraviolet B irradiation-mediated signaling pathway leading to increased interstitial collagenase (matrix-degrading metalloprotease (MMP)-1) and stromelysin-1 (MMP-3) mRNA levels in cultured human dermal f

artículo científico publicado en 1998

Chemokine receptors in head and neck cancer: association with metastatic spread and regulation during chemotherapy

artículo científico publicado en 2006

Comparing nitrosative versus oxidative stress toward zinc finger-dependent transcription. Unique role for NO.

artículo científico publicado en 2002

Contribution of UVB and UVA to UV-dependent stimulation of cyclooxygenase-2 expression in artificial epidermis

artículo científico publicado en 2004

Copper Homeostasis in the Model Organism C. elegans

artículo científico publicado en 2024

Copper ions strongly activate the phosphoinositide-3-kinase/Akt pathway independent of the generation of reactive oxygen species

artículo científico publicado en 2002

Corrigendum to "European contribution to the study of ROS: A summary of the findings and prospects for the future from the COST action BM1203 (EU-ROS)" [Redox Biol. 13 (2017) 94-162].

artículo científico publicado en 2017

Critical role of L-arginine in endothelial cell survival during oxidative stress

artículo científico publicado en 2003

Defenses against peroxynitrite

artículo científico publicado en 1999

Defenses against peroxynitrite: selenocompounds and flavonoids.

artículo científico publicado en 2003

Detection of a functional xenobiotic response element in a widely employed FoxO-responsive reporter construct

scientific article published on 15 October 2011

Dicumarol is a potent reversible inhibitor of gap junctional intercellular communication

artículo científico publicado en 2005

Different susceptibility of malignant versus nonmalignant human T cells toward ultraviolet A-1 radiation-induced apoptosis

artículo científico publicado en 2004

Differential capability of metabolic substrates to promote hepatocellular lipid accumulation

artículo científico publicado en 2018

Doxorubicin induces EGF receptor-dependent downregulation of gap junctional intercellular communication in rat liver epithelial cells

artículo científico publicado en 2005

Epicatechin selectively prevents nitration but not oxidation reactions of peroxynitrite

artículo científico publicado en 2001

Epidermal growth factor receptor is a common mediator of quinone-induced signaling leading to phosphorylation of connexin-43: role of glutathione and tyrosine phosphatases

artículo científico publicado en 2003

Epidermal growth factor- and stress-induced loss of gap junctional communication is mediated by ERK-1/ERK-2 but not ERK-5 in rat liver epithelial cells

artículo científico publicado en 2007

Epigallocatechin gallate-induced modulation of FoxO signaling in mammalian cells and C. elegans: FoxO stimulation is masked via PI3K/Akt activation by hydrogen peroxide formed in cell culture

artículo científico publicado en 2010

European contribution to the study of ROS: A summary of the findings and prospects for the future from the COST action BM1203 (EU-ROS).

artículo científico publicado en 2017

Evaluation of sulfur, selenium and tellurium catalysts with antioxidant potential

artículo científico publicado en 2003

Evidence that singlet oxygen-induced human T helper cell apoptosis is the basic mechanism of ultraviolet-A radiation phototherapy.

artículo científico publicado en 1997

Extracellular generation of hydrogen peroxide is responsible for activation of EGF receptor by ultraviolet A radiation

artículo científico publicado en 2006

FOXO1 cysteine-612 mediates stimulatory effects of the coregulators CBP and PGC1α on FOXO1 basal transcriptional activity

artículo científico publicado en 2018

Flavonoids as Putative Inducers of the Transcription Factors Nrf2, FoxO, and PPARγ

artículo científico publicado en 2017

Free radicals and related reactive species as mediators of tissue injury and disease: implications for Health.

artículo científico publicado en 2015

Functional analysis of the glutathione S-transferase 3 from Onchocerca volvulus (Ov-GST-3): a parasite GST confers increased resistance to oxidative stress in Caenorhabditis elegans

artículo científico publicado en 2003

Gadd153 sensitizes cells to endoplasmic reticulum stress by down-regulating Bcl2 and perturbing the cellular redox state

scientific journal article

Glutathione Peroxidase Protects against Peroxynitrite-mediated Oxidations

scientific article published in Journal of Biological Chemistry

Heavy metal ion-induced insulin-mimetic signaling.

artículo científico publicado en 2009

High efficiency of 5-aminolevulinate-photodynamic treatment using UVA irradiation

artículo científico publicado en 2001

Highlight: Oxidative Stress and Senescence

artículo científico publicado en 2008

Highlight: xenobiotics and cell signaling

scientific article published on 01 November 2010

HuR regulates gap junctional intercellular communication by controlling beta-catenin levels and adherens junction integrity

artículo científico publicado en 2009

Identification of cytosolic leucyl aminopeptidase (EC 3.4.11.1) as the major cysteinylglycine-hydrolysing activity in rat liver

artículo científico publicado en 2003

Inhibition of heme oxygenase-1 partially reverses the arsenite-mediated decrease of CYP1A1, CYP1A2, CYP3A23, and CYP3A2 catalytic activity in isolated rat hepatocytes

artículo científico publicado en 2011

Insulin suppresses the production of fibroblast growth factor 23 (FGF23)

artículo científico publicado en 2018

Insulin-like modulation of Akt/FoxO signaling by copper ions is independent of insulin receptor.

artículo científico publicado en 2014

Irradiation of cells with ultraviolet-A (320-400 nm) in the presence of cell culture medium elicits biological effects due to extracellular generation of hydrogen peroxide

artículo científico publicado en 2003

Label-free molecular mapping and assessment of glycogen in C. elegans

scientific article published on 01 March 2019

Lightening up the UV response by identification of the arylhydrocarbon receptor as a cytoplasmatic target for ultraviolet B radiation.

artículo científico publicado en 2007

Linking Alzheimer's disease to insulin resistance: the FoxO response to oxidative stress ⬇️

artículo científico publicado el 1 de noviembre de 2010

Loss of gap junctional intercellular communication in rat lung epithelial cells exposed to carbon or silica-based nanoparticles

artículo científico publicado en 2010

Loss of gap junctional intercellular communication in rat lung epithelial cells exposed to quartz particles

artículo científico publicado en 2009

Loss of the tyrosyl radical in mouse ribonucleotide reductase by (-)-epicatechin

artículo científico publicado en 2005

Methylated pentavalent arsenic metabolites are bifunctional inducers, as they induce cytochrome P450 1A1 and NAD(P)H:quinone oxidoreductase through AhR- and Nrf2-dependent mechanisms.

artículo científico publicado en 2013

Mitogen-activated protein kinase (p38-, JNK-, ERK-) activation pattern induced by extracellular and intracellular singlet oxygen and UVA

scientific article published on 01 March 1999

Mitogen-activated protein kinase activation by singlet oxygen and ultraviolet A.

artículo científico publicado en 2000

Modifications of glyceraldehyde-3-phosphate dehydrogenase induced by increasing concentrations of peroxynitrite: early recognition by 20S proteasome

artículo científico publicado en 2003

Modulation of FoxO signaling in human hepatoma cells by exposure to copper or zinc ions

artículo científico publicado en 2006

Modulation of cellular thiol status affects FoxO activity and life span.

artículo científico publicado en 2014

Multifaceted functions of the forkhead box transcription factors FoxO1 and FoxO3 in skin

artículo científico publicado en 2017

Nickel and copper ion-induced stress signaling in human hepatoma cells: analysis of phosphoinositide 3'-kinase/Akt signaling.

artículo científico publicado en 2008

Nitrotyrosine and protein carbonyls are equally distributed in HT22 cells after nitrosative stress.

artículo científico publicado en 2006

Non-linear impact of glutathione depletion on C. elegans life span and stress resistance

artículo científico publicado en 2016

Nuclear trapping of inactive FOXO1 by the Nrf2 activator diethyl maleate

artículo científico publicado en 2018

Oxidative modification and nitration of human low-density lipoproteins by the reaction of hypochlorous acid with nitrite

artículo científico publicado en 1997

Peroxynitrite activates the phosphoinositide 3-kinase/Akt pathway in human skin primary fibroblasts

artículo científico publicado en 2000

Peroxynitrite signaling: receptor tyrosine kinases and activation of stress-responsive pathways.

artículo científico publicado en 2002

Peroxynitrite: From interception to signaling.

artículo científico publicado en 2016

Polyphenols of cocoa: inhibition of mammalian 15-lipoxygenase

artículo científico publicado en 2001

Posttranscriptional regulation of FOXO expression: microRNAs and beyond

artículo científico publicado en 2016

Posttranscriptional regulation of connexin-43 expression.

artículo científico publicado en 2012

Protection against peroxynitrite by selenoproteins

artículo científico publicado en 1998

Protection by organotellurium compounds against peroxynitrite-mediated oxidation and nitration reactions

artículo científico publicado en 1998

Protein modification elicited by oxidized low-density lipoprotein (LDL) in endothelial cells: protection by (-)-epicatechin

scientific article published on 22 December 2006

Protein oxidation and proteolysis by the nonradical oxidants singlet oxygen or peroxynitrite

artículo científico publicado en 2001

Quinone-induced Cdc25A inhibition causes ERK-dependent connexin phosphorylation

artículo científico publicado en 2005

Rac upregulates tissue inhibitor of metalloproteinase-1 expression by redox-dependent activation of extracellular signal-regulated kinase signaling.

artículo científico publicado en 2006

Reactivity of lipophilic diSchiff-Base coordinated copper in rat hepatocytes

artículo científico publicado en 1996

Redox regulation of FoxO transcription factors

artículo científico publicado en 2015

Regulation of glucose-6-phosphatase gene expression by insulin and metformin.

artículo científico publicado en 2009

Reversible conversion of nitroxyl anion to nitric oxide

artículo científico publicado en 2002

Role of copper, zinc, selenium and tellurium in the cellular defense against oxidative and nitrosative stress.

artículo científico publicado en 2003

Role of myoglobin in the antioxidant defense of the heart

artículo científico publicado en 2004

Selenenyl iodide: a new substrate for mammalian thioredoxin reductase

artículo científico publicado en 2003

Selenium-binding protein 1 (SELENBP1) is a marker of mature adipocytes

scientific article published on 10 November 2018

Selenoprotein P

artículo científico publicado en 2002

Selenoprotein P protects low-density lipoprotein against oxidation.

artículo científico publicado en 2004

Selenoproteins: Antioxidant selenoenzymes and beyond

artículo científico publicado en 2016

Signal transduction, receptors, mediators and genes: younger than ever - the 13th meeting of the Signal Transduction Society focused on aging and immunology

artículo científico publicado en 2010

Signaling effects of menadione: from tyrosine phosphatase inactivation to connexin phosphorylation

artículo científico publicado en 2004

Singlet oxygen inactivates protein tyrosine phosphatase-1B by oxidation of the active site cysteine

artículo científico publicado en 2006

Singlet oxygen mediates the activation of JNK by UVA radiation in human skin fibroblasts

scientific article published on 01 May 1997

Singlet oxygen-induced attenuation of growth factor signaling: possible role of ceramides

artículo científico publicado en 2004

Singlet oxygen-induced signaling effects in mammalian cells.

artículo científico publicado en 2003

Special Issue: cell-cell communication in development and disease

artículo científico publicado en 2012

Stimulation of phosphoinositide 3-kinase/Akt signaling by copper and zinc ions: mechanisms and consequences.

artículo científico publicado en 2007

Stress and biological aging: A double-edged sword.

artículo científico publicado en 2015

Sugar-derived AGEs accelerate pharyngeal pumping rate and increase the lifespan of Caenorhabditis elegans

artículo científico publicado en 2019

Thalidomide resistance is based on the capacity of the glutathione-dependent antioxidant defense.

artículo científico publicado en 2008

The GID ubiquitin ligase complex is a regulator of AMPK activity and organismal lifespan

scientific article published on 03 December 2019

Toxic and signaling effects of photochemically or chemically generated singlet oxygen in biological systems.

artículo científico publicado en 1997

Zinc fingers as biologic redox switches?

artículo científico publicado en 2009

Lista de obras de Lars-Oliver Klotz

(-)-Epicatechin inhibits nitration and dimerization of tyrosine in hydrophilic as well as hydrophobic environments

1,4-Naphthoquinones as inducers of oxidative damage and stress signaling in HaCaT human keratinocytes.

1,4-naphthoquinones: from oxidative damage to cellular and inter-cellular signaling

2-Methyl-1,4-naphthoquinone, vitamin K(3), decreases gap-junctional intercellular communication via activation of the epidermal growth factor receptor/extracellular signal-regulated kinase cascade.

A Caenorhabditis elegans ortholog of human selenium-binding protein 1 is a pro-aging factor protecting against selenite toxicity

Activation of ErbB2 by 2-methyl-1,4-naphthoquinone (menadione) in human keratinocytes: role of EGFR and protein tyrosine phosphatases

Activation of JNK and p38 but not ERK MAP kinases in human skin cells by 5-aminolevulinate-photodynamic therapy

Activation pattern of mitogen-activated protein kinases elicited by peroxynitrite: attenuation by selenite supplementation

Acute and long-term effects of arsenite in HepG2 cells: modulation of insulin signaling

Amphiphilic properties of (-)-epicatechin and their significance for protection of cells against peroxynitrite

Arsenite-induced stress signaling: modulation of the phosphoinositide 3'-kinase/Akt/FoxO signaling cascade

Cellular adaptation to xenobiotics: Interplay between xenosensors, reactive oxygen species and FOXO transcription factors

Central role of Ferrous/Ferric iron in the ultraviolet B irradiation-mediated signaling pathway leading to increased interstitial collagenase (matrix-degrading metalloprotease (MMP)-1) and stromelysin-1 (MMP-3) mRNA levels in cultured human dermal f

Chemokine receptors in head and neck cancer: association with metastatic spread and regulation during chemotherapy

Comparing nitrosative versus oxidative stress toward zinc finger-dependent transcription. Unique role for NO.

Contribution of UVB and UVA to UV-dependent stimulation of cyclooxygenase-2 expression in artificial epidermis

Copper Homeostasis in the Model Organism C. elegans

Copper ions strongly activate the phosphoinositide-3-kinase/Akt pathway independent of the generation of reactive oxygen species

Corrigendum to "European contribution to the study of ROS: A summary of the findings and prospects for the future from the COST action BM1203 (EU-ROS)" [Redox Biol. 13 (2017) 94-162].

Critical role of L-arginine in endothelial cell survival during oxidative stress

Defenses against peroxynitrite

Defenses against peroxynitrite: selenocompounds and flavonoids.

Detection of a functional xenobiotic response element in a widely employed FoxO-responsive reporter construct

Dicumarol is a potent reversible inhibitor of gap junctional intercellular communication

Different susceptibility of malignant versus nonmalignant human T cells toward ultraviolet A-1 radiation-induced apoptosis

Differential capability of metabolic substrates to promote hepatocellular lipid accumulation

Doxorubicin induces EGF receptor-dependent downregulation of gap junctional intercellular communication in rat liver epithelial cells

Epicatechin selectively prevents nitration but not oxidation reactions of peroxynitrite

Epidermal growth factor receptor is a common mediator of quinone-induced signaling leading to phosphorylation of connexin-43: role of glutathione and tyrosine phosphatases

Epidermal growth factor- and stress-induced loss of gap junctional communication is mediated by ERK-1/ERK-2 but not ERK-5 in rat liver epithelial cells

Epigallocatechin gallate-induced modulation of FoxO signaling in mammalian cells and C. elegans: FoxO stimulation is masked via PI3K/Akt activation by hydrogen peroxide formed in cell culture

European contribution to the study of ROS: A summary of the findings and prospects for the future from the COST action BM1203 (EU-ROS).

Evaluation of sulfur, selenium and tellurium catalysts with antioxidant potential

Evidence that singlet oxygen-induced human T helper cell apoptosis is the basic mechanism of ultraviolet-A radiation phototherapy.

Extracellular generation of hydrogen peroxide is responsible for activation of EGF receptor by ultraviolet A radiation

FOXO1 cysteine-612 mediates stimulatory effects of the coregulators CBP and PGC1α on FOXO1 basal transcriptional activity

Flavonoids as Putative Inducers of the Transcription Factors Nrf2, FoxO, and PPARγ

Free radicals and related reactive species as mediators of tissue injury and disease: implications for Health.

Functional analysis of the glutathione S-transferase 3 from Onchocerca volvulus (Ov-GST-3): a parasite GST confers increased resistance to oxidative stress in Caenorhabditis elegans

Gadd153 sensitizes cells to endoplasmic reticulum stress by down-regulating Bcl2 and perturbing the cellular redox state

Glutathione Peroxidase Protects against Peroxynitrite-mediated Oxidations

Heavy metal ion-induced insulin-mimetic signaling.

High efficiency of 5-aminolevulinate-photodynamic treatment using UVA irradiation

Highlight: Oxidative Stress and Senescence

Highlight: xenobiotics and cell signaling

HuR regulates gap junctional intercellular communication by controlling beta-catenin levels and adherens junction integrity

Identification of cytosolic leucyl aminopeptidase (EC 3.4.11.1) as the major cysteinylglycine-hydrolysing activity in rat liver

Inhibition of heme oxygenase-1 partially reverses the arsenite-mediated decrease of CYP1A1, CYP1A2, CYP3A23, and CYP3A2 catalytic activity in isolated rat hepatocytes

Insulin suppresses the production of fibroblast growth factor 23 (FGF23)

Insulin-like modulation of Akt/FoxO signaling by copper ions is independent of insulin receptor.

Irradiation of cells with ultraviolet-A (320-400 nm) in the presence of cell culture medium elicits biological effects due to extracellular generation of hydrogen peroxide

Label-free molecular mapping and assessment of glycogen in C. elegans

Lightening up the UV response by identification of the arylhydrocarbon receptor as a cytoplasmatic target for ultraviolet B radiation.

Linking Alzheimer's disease to insulin resistance: the FoxO response to oxidative stress ⬇️

Loss of gap junctional intercellular communication in rat lung epithelial cells exposed to carbon or silica-based nanoparticles

Loss of gap junctional intercellular communication in rat lung epithelial cells exposed to quartz particles

Loss of the tyrosyl radical in mouse ribonucleotide reductase by (-)-epicatechin

Methylated pentavalent arsenic metabolites are bifunctional inducers, as they induce cytochrome P450 1A1 and NAD(P)H:quinone oxidoreductase through AhR- and Nrf2-dependent mechanisms.

Mitogen-activated protein kinase (p38-, JNK-, ERK-) activation pattern induced by extracellular and intracellular singlet oxygen and UVA

Mitogen-activated protein kinase activation by singlet oxygen and ultraviolet A.

Modifications of glyceraldehyde-3-phosphate dehydrogenase induced by increasing concentrations of peroxynitrite: early recognition by 20S proteasome

Modulation of FoxO signaling in human hepatoma cells by exposure to copper or zinc ions

Modulation of cellular thiol status affects FoxO activity and life span.

Multifaceted functions of the forkhead box transcription factors FoxO1 and FoxO3 in skin

Nickel and copper ion-induced stress signaling in human hepatoma cells: analysis of phosphoinositide 3'-kinase/Akt signaling.

Nitrotyrosine and protein carbonyls are equally distributed in HT22 cells after nitrosative stress.

Non-linear impact of glutathione depletion on C. elegans life span and stress resistance

Nuclear trapping of inactive FOXO1 by the Nrf2 activator diethyl maleate

Oxidative modification and nitration of human low-density lipoproteins by the reaction of hypochlorous acid with nitrite

Peroxynitrite activates the phosphoinositide 3-kinase/Akt pathway in human skin primary fibroblasts

Peroxynitrite signaling: receptor tyrosine kinases and activation of stress-responsive pathways.

Peroxynitrite: From interception to signaling.

Polyphenols of cocoa: inhibition of mammalian 15-lipoxygenase

Posttranscriptional regulation of FOXO expression: microRNAs and beyond

Posttranscriptional regulation of connexin-43 expression.

Protection against peroxynitrite by selenoproteins

Protection by organotellurium compounds against peroxynitrite-mediated oxidation and nitration reactions

Protein modification elicited by oxidized low-density lipoprotein (LDL) in endothelial cells: protection by (-)-epicatechin

Protein oxidation and proteolysis by the nonradical oxidants singlet oxygen or peroxynitrite