Lista de obras - María Vilanova Brugués

(1)H, (13)C and (15)N resonance assignments of the Onconase FL-G zymogen.

artículo científico publicado en 2012

A Cytotoxic Ribonuclease Variant with a Discontinuous Nuclear Localization Signal Constituted by Basic Residues Scattered Over Three Areas of the Molecule

artículo científico publicado en 2006

A Nuclear-Directed Ribonuclease Variant Targets Cancer Stem Cells and Inhibits Migration and Invasion of Breast Cancer Cells

artículo científico publicado en 2021

A family of manganese complexes containing heterocyclic-based ligands with cytotoxic properties.

artículo científico publicado en 2018

A nuclear localization sequence endows human pancreatic ribonuclease with cytotoxic activity.

artículo científico publicado en 2004

A nuclear-directed human pancreatic ribonuclease (PE5) targets the metabolic phenotype of cancer cells.

artículo científico publicado en 2016

A truncated apoptin protein variant selectively kills cancer cells

artículo científico publicado en 2017

Analysis of the thermal unfolding of porcine procarboxypeptidase A and its functional pieces by differential scnning calorimetry

artículo científico publicado en 1988

Apoptin, a Versatile Protein with Selective Antitumor Activity.

artículo científico publicado en 2018

Asymmetric kinetics of protein structural changes.

artículo científico publicado en 2009

Bactericidal Activity Engineered on Human Pancreatic Ribonuclease and Onconase

artículo científico publicado en 2009

Carbodiimide EDC induces cross-links that stabilize RNase A C-dimer against dissociation: EDC adducts can affect protein net charge, conformation, and activity.

artículo científico publicado en 2009

Characterization of the dimerization process of a domain-swapped dimeric variant of human pancreatic ribonuclease.

artículo científico publicado en 2006

Conformational predictive studies on the activation seoment of pancreatic procarboxypeptidases

artículo científico publicado en 1987

Construction of Highly Stable Cytotoxic Nuclear-Directed Ribonucleases

scientific article published on 11 December 2018

Contribution of the C30/C75 disulfide bond to the biological properties of onconase.

artículo científico publicado en 2008

Crowding agents and osmolytes provide insight into the formation and dissociation of RNase A oligomers

artículo científico publicado en 2010

Destabilizing mutations alter the hydrogen exchange mechanism in ribonuclease A.

artículo científico publicado en 2008

Distinct unfolding and refolding pathways of ribonuclease a revealed by heating and cooling temperature jumps.

artículo científico publicado en 2008

Formation, Structure, and Dissociation of the Ribonuclease S Three-dimensional Domain-swapped Dimer

scientific article published in Journal of Biological Chemistry

Human pancreatic ribonuclease presents higher endonucleolytic activity than ribonuclease A.

artículo científico publicado en 2008

Insights into the mechanism of Apoptin's exquisitely selective anti-tumor action from atomic level characterization of its conformation and dynamics.

artículo científico publicado en 2016

Interactions crucial for three-dimensional domain swapping in the HP-RNase variant PM8.

artículo científico publicado en 2011

Intracellular pathway of Onconase that enables its delivery to the cytosol

artículo científico publicado en 2007

Investigating the effects of double mutation C30A/C75A on onconase structure: Studies at atomic resolution

artículo científico publicado en 2014

Mapping the stability clusters in bovine pancreatic ribonuclease A.

artículo científico publicado en 2009

NMR spectroscopy reveals that RNase A is chiefly denatured in 40% acetic acid: implications for oligomer formation by 3D domain swapping.

artículo científico publicado en 2010

Pressure versus heat-induced unfolding of ribonuclease A: the case of hydrophobic interactions within a chain-folding initiation site.

artículo científico publicado en 1999

Pressure versus temperature unfolding of ribonuclease A: an FTIR spectroscopic characterization of 10 variants at the carboxy-terminal site

artículo científico publicado en 2001

Pressure- and temperature-induced unfolding studies: thermodynamics of core hydrophobicity and packing of ribonuclease A

artículo científico publicado en 2006

Pressure-jump-induced kinetics reveals a hydration dependent folding/unfolding mechanism of ribonuclease A

artículo científico publicado en 2006

Production of Engineered Human Pancreatic Ribonucleases, Solving Expression and Purification Problems, and Enhancing Thermostability

scientific article published on 01 October 1999

Quantitative analysis, using MALDI-TOF mass spectrometry, of the N-terminal hydrolysis and cyclization reactions of the activation process of onconase.

artículo científico publicado en 2004

Stabilization of human pancreatic ribonuclease through mutation at its N-terminal edge

artículo científico publicado en 2002

Structural Insights into Subunits Assembly and the Oxyester Splicing Mechanism of Neq pol Split Intein

artículo científico publicado en 2018

The activation segment of procarboxypeptidase A from porcine pancreas constitutes a folded structural domain

article

The contribution of noncatalytic phosphate-binding subsites to the mechanism of bovine pancreatic ribonuclease A

artículo científico publicado en 1998

The contribution of the residues from the main hydrophobic core of ribonuclease A to its pressure-folding transition state.

artículo científico publicado en 2006

The nuclear transport capacity of a human-pancreatic ribonuclease variant is critical for its cytotoxicity.

artículo científico publicado en 2010

The structural determinants that lead to the formation of particular oligomeric structures in the pancreatic-type ribonuclease family.

artículo científico publicado en 2008

The structure of an engineered domain-swapped ribonuclease dimer and its implications for the evolution of proteins toward oligomerization

artículo científico publicado en 2001

The use of pressure-jump relaxation kinetics to study protein folding landscapes

artículo científico publicado en 2006

Thermal unfolding of eosinophil cationic protein/ribonuclease 3: a nonreversible process.

artículo científico publicado en 2006

Three-dimensional structure of a human pancreatic ribonuclease variant, a step forward in the design of cytotoxic ribonucleases

artículo científico publicado en 2000

Towards tricking a pathogen's protease into fighting infection: the 3D structure of a stable circularly permuted onconase variant cleavedby HIV-1 protease

artículo científico publicado en 2013

Transcriptional profiling of NCI/ADR-RES cells unveils a complex network of signaling pathways and molecular mechanisms of drug resistance

artículo científico publicado en 2018

Urea-gradient gel electrophoresis studies on the association of procarboxypeptidases A and B, proproteinase E, and their tryptic activation products

artículo científico publicado en 1985

Valine 108, a Chain-Folding Initiation Site-Belonging Residue, Crucial for the Ribonuclease A Stability

artículo científico publicado en 1999

Lista de obras de María Vilanova Brugués

(1)H, (13)C and (15)N resonance assignments of the Onconase FL-G zymogen.

A Cytotoxic Ribonuclease Variant with a Discontinuous Nuclear Localization Signal Constituted by Basic Residues Scattered Over Three Areas of the Molecule

A Nuclear-Directed Ribonuclease Variant Targets Cancer Stem Cells and Inhibits Migration and Invasion of Breast Cancer Cells

A family of manganese complexes containing heterocyclic-based ligands with cytotoxic properties.

A nuclear localization sequence endows human pancreatic ribonuclease with cytotoxic activity.

A nuclear-directed human pancreatic ribonuclease (PE5) targets the metabolic phenotype of cancer cells.

A truncated apoptin protein variant selectively kills cancer cells

Analysis of the thermal unfolding of porcine procarboxypeptidase A and its functional pieces by differential scnning calorimetry

Apoptin, a Versatile Protein with Selective Antitumor Activity.

Asymmetric kinetics of protein structural changes.

Bactericidal Activity Engineered on Human Pancreatic Ribonuclease and Onconase

Carbodiimide EDC induces cross-links that stabilize RNase A C-dimer against dissociation: EDC adducts can affect protein net charge, conformation, and activity.

Characterization of the dimerization process of a domain-swapped dimeric variant of human pancreatic ribonuclease.

Conformational predictive studies on the activation seoment of pancreatic procarboxypeptidases

Construction of Highly Stable Cytotoxic Nuclear-Directed Ribonucleases

Contribution of the C30/C75 disulfide bond to the biological properties of onconase.

Crowding agents and osmolytes provide insight into the formation and dissociation of RNase A oligomers

Destabilizing mutations alter the hydrogen exchange mechanism in ribonuclease A.

Distinct unfolding and refolding pathways of ribonuclease a revealed by heating and cooling temperature jumps.

Formation, Structure, and Dissociation of the Ribonuclease S Three-dimensional Domain-swapped Dimer

Human pancreatic ribonuclease presents higher endonucleolytic activity than ribonuclease A.

Insights into the mechanism of Apoptin's exquisitely selective anti-tumor action from atomic level characterization of its conformation and dynamics.

Interactions crucial for three-dimensional domain swapping in the HP-RNase variant PM8.

Intracellular pathway of Onconase that enables its delivery to the cytosol

Investigating the effects of double mutation C30A/C75A on onconase structure: Studies at atomic resolution

Mapping the stability clusters in bovine pancreatic ribonuclease A.

NMR spectroscopy reveals that RNase A is chiefly denatured in 40% acetic acid: implications for oligomer formation by 3D domain swapping.

Pressure versus heat-induced unfolding of ribonuclease A: the case of hydrophobic interactions within a chain-folding initiation site.

Pressure versus temperature unfolding of ribonuclease A: an FTIR spectroscopic characterization of 10 variants at the carboxy-terminal site

Pressure- and temperature-induced unfolding studies: thermodynamics of core hydrophobicity and packing of ribonuclease A

Pressure-jump-induced kinetics reveals a hydration dependent folding/unfolding mechanism of ribonuclease A

Production of Engineered Human Pancreatic Ribonucleases, Solving Expression and Purification Problems, and Enhancing Thermostability

Quantitative analysis, using MALDI-TOF mass spectrometry, of the N-terminal hydrolysis and cyclization reactions of the activation process of onconase.

Stabilization of human pancreatic ribonuclease through mutation at its N-terminal edge

Structural Insights into Subunits Assembly and the Oxyester Splicing Mechanism of Neq pol Split Intein

The activation segment of procarboxypeptidase A from porcine pancreas constitutes a folded structural domain

The contribution of noncatalytic phosphate-binding subsites to the mechanism of bovine pancreatic ribonuclease A

The contribution of the residues from the main hydrophobic core of ribonuclease A to its pressure-folding transition state.

The nuclear transport capacity of a human-pancreatic ribonuclease variant is critical for its cytotoxicity.

The structural determinants that lead to the formation of particular oligomeric structures in the pancreatic-type ribonuclease family.

The structure of an engineered domain-swapped ribonuclease dimer and its implications for the evolution of proteins toward oligomerization

The use of pressure-jump relaxation kinetics to study protein folding landscapes

Thermal unfolding of eosinophil cationic protein/ribonuclease 3: a nonreversible process.

Three-dimensional structure of a human pancreatic ribonuclease variant, a step forward in the design of cytotoxic ribonucleases

Towards tricking a pathogen's protease into fighting infection: the 3D structure of a stable circularly permuted onconase variant cleavedby HIV-1 protease

Transcriptional profiling of NCI/ADR-RES cells unveils a complex network of signaling pathways and molecular mechanisms of drug resistance

Urea-gradient gel electrophoresis studies on the association of procarboxypeptidases A and B, proproteinase E, and their tryptic activation products

Valine 108, a Chain-Folding Initiation Site-Belonging Residue, Crucial for the Ribonuclease A Stability