Lista de obras - Mikael Sigvardsson - Dominio Público Uruguay

A dose-dependent role for EBF1 in repressing non-B-cell-specific genes.

artículo científico publicado en 2011

A global network of transcription factors, involving E2A, EBF1 and Foxo1, that orchestrates B cell fate

artículo científico publicado en 2010

A human early B-cell factor-like protein participates in the regulation of the human CD19 promoter.

artículo científico

ARID1a Associates with Lymphoid-Restricted Transcription Factors and Has an Essential Role in T Cell Development

artículo científico publicado en 2020

Accumulating Mitochondrial DNA Mutations Drive Premature Hematopoietic Aging Phenotypes Distinct from Physiological Stem Cell Aging ⬇️

artículo científico publicado el 6 de mayo de 2011

An epigenetic component of hematopoietic stem cell aging amenable to reprogramming into a young state.

artículo científico publicado en 2013

Analysis of Oct2-isoform expression in lipopolysaccharide-stimulated B lymphocytes.

artículo científico publicado en 1994

B-lineage commitment prior to surface expression of B220 and CD19 on hematopoietic progenitor cells

artículo científico publicado en 2008

CD40 stimulation induces Pax5/BSAP and EBF activation through a APE/Ref-1-dependent redox mechanism

artículo científico publicado en 2004

Characterization of the joining chain (J-chain) promoter

artículo científico publicado en 1993

Cited2 is an essential regulator of adult hematopoietic stem cells

artículo científico publicado en 2009

Complementary signaling through flt3 and interleukin-7 receptor alpha is indispensable for fetal and adult B cell genesis

artículo científico publicado en 2003

Context-dependent regulation of hematopoietic lineage choice by HEBAlt

artículo científico publicado en 2010

Critical role of FLT3 ligand in IL-7 receptor independent T lymphopoiesis and regulation of lymphoid-primed multipotent progenitors

scientific article published on 31 May 2007

Dissection of progenitor compartments resolves developmental trajectories in B-lymphopoiesis.

artículo científico publicado en 2018

Distinct roles of mesenchymal stem and progenitor cells during the development of acute myeloid leukemia in mice

artículo científico publicado en 2018

E2A transcription factors limit expression of Gata3 to facilitate T lymphocyte lineage commitment.

artículo científico publicado en 2013

EBF and E47 collaborate to induce expression of the endogenous immunoglobulin surrogate light chain genes

artículo científico publicado en 1997

Early B-cell factor (O/E-1) is a promoter of adipogenesis and involved in control of genes important for terminal adipocyte differentiation.

artículo científico publicado en 2002

Early B-cell factor 1 regulates the expansion of B-cell progenitors in a dose-dependent manner

artículo científico publicado en 2013

Ectopic expression of PAX5 promotes maintenance of biphenotypic myeloid progenitors coexpressing myeloid and B-cell lineage-associated genes

artículo científico publicado en 2007

Elucidation of the phenotypic, functional, and molecular topography of a myeloerythroid progenitor cell hierarchy.

artículo científico publicado en 2007

Epigenetic chromatin states uniquely define the developmental plasticity of murine hematopoietic stem cells

artículo científico publicado en 2009

Essential functions for ID proteins at multiple checkpoints in invariant NKT cell development.

artículo científico publicado en 2013

Exit of pediatric pre-B acute lymphoblastic leukaemia cells from the bone marrow to the peripheral blood is not associated with cell maturation or alterations in gene expression

artículo científico publicado en 2008

Expression of integrin α2 receptor in human cord blood CD34+CD38-CD90+ stem cells engrafting long-term in NOD/SCID-IL2Rγ(c) null mice

artículo científico publicado en 2013

Ezh2 Represses Transcription of Innate Lymphoid Genes in B Lymphocyte Progenitors and Maintains the B-2 Cell Fate

artículo científico publicado en 2020

Fetal hepatic expression of 5-lipoxygenase activating protein is confined to colonizing hematopoietic cells

artículo científico publicado en 2009

Functionally distinct hematopoietic stem cells modulate hematopoietic lineage potential during aging by a mechanism of clonal expansion

artículo científico publicado en 2010

Gene expression analysis suggests that EBF-1 and PPARgamma2 induce adipogenesis of NIH-3T3 cells with similar efficiency and kinetics

artículo científico publicado en 2005

Genomics based analysis of interactions between developing B-lymphocytes and stromal cells reveal complex interactions and two-way communication.

artículo científico publicado en 2010

HOXA10 is a critical regulator for hematopoietic stem cells and erythroid/megakaryocyte development

artículo científico publicado en 2007

IL-7 mediates Ebf-1-dependent lineage restriction in early lymphoid progenitors.

artículo científico publicado en 2011

Identification of Flt3+ lympho-myeloid stem cells lacking erythro-megakaryocytic potential a revised road map for adult blood lineage commitment.

artículo científico publicado en 2005

Identification of Lin(-)Sca1(+)kit(+)CD34(+)Flt3- short-term hematopoietic stem cells capable of rapidly reconstituting and rescuing myeloablated transplant recipients.

artículo científico publicado en 2004

Immune status and inflammatory response differ locally and systemically in severe acute pancreatitis.

artículo científico publicado en 2006

Induction ofID2Expression by Hypoxia-inducible Factor-1

artículo científico publicado en 2004

Inhibition of p300/CBP by early B-cell factor

artículo científico publicado en 2003

Interleukin-7-induced Stat-5 acts in synergy with Flt-3 signaling to stimulate expansion of hematopoietic progenitor cells.

artículo científico publicado en 2010

Intrinsic inhibition of transcription factor E2A by HLH proteins ABF-1 and Id2 mediates reprogramming of neoplastic B cells in Hodgkin lymphoma

artículo científico publicado en 2005

Lin28b controls a neonatal to adult switch in B cell positive selection

artículo científico publicado en 2019

Lipopolysaccharide-induced fever depends on prostaglandin E2 production specifically in brain endothelial cells

artículo científico publicado en 2012

Load and lock: the molecular mechanisms of B-lymphocyte commitment.

artículo científico publicado en 2010

Loss of bHLH transcription factor E2A activity in primary effusion lymphoma confers resistance to apoptosis.

artículo científico publicado en 2007

Loss- and gain-of-function analyses reveal targets of Pax6 in the developing mouse telencephalon.

artículo científico

Mice with an inactivated joining chain locus have perturbed IgM secretion

artículo científico publicado en 1998

Molecular characterization of prospectively isolated multipotent mesenchymal progenitors provides new insight into the cellular identity of mesenchymal stem cells in mouse bone marrow.

artículo científico publicado en 2012

Molecular evidence for hierarchical transcriptional lineage priming in fetal and adult stem cells and multipotent progenitors

artículo científico publicado en 2007

Molecular profiling reveals distinct functional attributes of CD1d-restricted natural killer (NK) T cell subsets

artículo científico publicado en 2008

Multilineage priming of enhancer repertoires precedes commitment to the B and myeloid cell lineages in hematopoietic progenitors.

artículo científico

Neuroblastoma and pre-B lymphoma cells share expression of key transcription factors but display tissue restricted target gene expression

artículo científico publicado en 2004

New light on the biology and developmental potential of haematopoietic stem cells and progenitor cells.

artículo científico publicado en 2009

Nuclear factor of activated T cells regulates osteopontin expression in arterial smooth muscle in response to diabetes-induced hyperglycemia

artículo científico publicado en 2009

Oct proteins are qualitative rather than quantitative regulators of kappa transcription

scientific article published on 01 October 1997

Olf/EBF proteins are expressed in neuroblastoma cells: potential regulators of the Chromogranin A and SCG10 promoters

artículo científico publicado en 2004

PAX5 is part of a functional transcription factor network targeted in lymphoid leukemia

artículo científico publicado en 2019

Pearson correlation analysis of microarray data allows for the identification of genetic targets for early B-cell factor.

artículo científico publicado en 2004

Permissive roles of hematopoietin and cytokine tyrosine kinase receptors in early T-cell development

artículo científico publicado en 2007

Pioneering, chromatin remodeling, and epigenetic constraint in early T-cell gene regulation by SPI1 (PU.1)

article

Positive intergenic feedback circuitry, involving EBF1 and FOXO1, orchestrates B-cell fate

artículo científico publicado en 2012

Predictive screening for regulators of conserved functional gene modules (gene batteries) in mammals

artículo científico publicado en 2005

Primary mesenchymal stem and progenitor cells from bone marrow lack expression of CD44 protein

artículo científico publicado en 2012

Probabilistic estimation of microarray data reliability and underlying gene expression

artículo científico publicado en 2003

RNA analysis of B cell lines arrested at defined stages of differentiation allows for an approximation of gene expression patterns during B cell development.

artículo científico publicado en 2003

Real-time analysis of Oct protein-octamer interaction and transcription complex assembly

artículo científico publicado en 1995

Reduced repression of cytokine signaling ameliorates age‐induced decline in hematopoietic stem cell function ⬇️

artículo científico publicado el 27 de agosto de 2012

Redundant Regulation of T Cell Differentiation and TCRα Gene Expression by the Transcription Factors LEF-1 and TCF-1 ⬇️

artículo científico publicado el 1 de enero de 1998

Shaping up a lineage--lessons from B lymphopoesis.

scientific article published on 06 March 2010

Single-cell analysis of early B-lymphocyte development suggests independent regulation of lineage specification and commitment in vivo.

artículo científico publicado en 2012

Single-cell analysis of the common lymphoid progenitor compartment reveals functional and molecular heterogeneity.

artículo científico publicado en 2009

Splenic B cells from Hymenolepis diminuta-infected mice ameliorate colitis independent of T cells and via cooperation with macrophages.

artículo científico publicado en 2014

Stimulation of kappa transcription by a decamer-dependent, synergistic mechanism.

artículo científico publicado en 1995

Structural Determination of Functional Domains in Early B-cell Factor (EBF) Family of Transcription Factors Reveals Similarities to Rel DNA-binding Proteins and a Novel Dimerization Motif

artículo científico publicado en 2010

The CD53 and CEACAM-1 genes are genetic targets for early B cell factor.

artículo científico

The Cxcl12, periostin, and Ccl9 genes are direct targets for early B-cell factor in OP-9 stroma cells.

artículo científico publicado en 2007

The EBF/Olf/Collier family of transcription factors: regulators of differentiation in cells originating from all three embryonal germ layers.

artículo científico publicado en 2002

The Notch-2 gene is regulated by Wnt signaling in cultured colorectal cancer cells

artículo científico publicado en 2011

The molecular signature of MDS stem cells supports a stem-cell origin of 5q myelodysplastic syndromes

artículo científico publicado en 2007

The pT alpha promoter and enhancer are direct targets for transactivation by E box-binding proteins

artículo científico publicado en 2002

The roles of transcription factors in B lymphocyte commitment, development, and transformation

artículo científico publicado en 2004

The transcription factors E2A and HEB act in concert to induce the expression of FOXO1 in the common lymphoid progenitor

artículo científico publicado en 2011

Transcription factor dose links development to disease ⬇️

artículo científico publicado el 1 de noviembre de 2012

Lista de obras de Mikael Sigvardsson

A dose-dependent role for EBF1 in repressing non-B-cell-specific genes.

A global network of transcription factors, involving E2A, EBF1 and Foxo1, that orchestrates B cell fate

A human early B-cell factor-like protein participates in the regulation of the human CD19 promoter.

ARID1a Associates with Lymphoid-Restricted Transcription Factors and Has an Essential Role in T Cell Development

Accumulating Mitochondrial DNA Mutations Drive Premature Hematopoietic Aging Phenotypes Distinct from Physiological Stem Cell Aging ⬇️

An epigenetic component of hematopoietic stem cell aging amenable to reprogramming into a young state.

Analysis of Oct2-isoform expression in lipopolysaccharide-stimulated B lymphocytes.

B-lineage commitment prior to surface expression of B220 and CD19 on hematopoietic progenitor cells

CD40 stimulation induces Pax5/BSAP and EBF activation through a APE/Ref-1-dependent redox mechanism

Characterization of the joining chain (J-chain) promoter

Cited2 is an essential regulator of adult hematopoietic stem cells

Complementary signaling through flt3 and interleukin-7 receptor alpha is indispensable for fetal and adult B cell genesis

Context-dependent regulation of hematopoietic lineage choice by HEBAlt

Critical role of FLT3 ligand in IL-7 receptor independent T lymphopoiesis and regulation of lymphoid-primed multipotent progenitors

Dissection of progenitor compartments resolves developmental trajectories in B-lymphopoiesis.

Distinct roles of mesenchymal stem and progenitor cells during the development of acute myeloid leukemia in mice

E2A transcription factors limit expression of Gata3 to facilitate T lymphocyte lineage commitment.

EBF and E47 collaborate to induce expression of the endogenous immunoglobulin surrogate light chain genes

Early B-cell factor (O/E-1) is a promoter of adipogenesis and involved in control of genes important for terminal adipocyte differentiation.

Early B-cell factor 1 regulates the expansion of B-cell progenitors in a dose-dependent manner

Ectopic expression of PAX5 promotes maintenance of biphenotypic myeloid progenitors coexpressing myeloid and B-cell lineage-associated genes

Elucidation of the phenotypic, functional, and molecular topography of a myeloerythroid progenitor cell hierarchy.

Epigenetic chromatin states uniquely define the developmental plasticity of murine hematopoietic stem cells

Essential functions for ID proteins at multiple checkpoints in invariant NKT cell development.

Exit of pediatric pre-B acute lymphoblastic leukaemia cells from the bone marrow to the peripheral blood is not associated with cell maturation or alterations in gene expression

Expression of integrin α2 receptor in human cord blood CD34+CD38-CD90+ stem cells engrafting long-term in NOD/SCID-IL2Rγ(c) null mice

Ezh2 Represses Transcription of Innate Lymphoid Genes in B Lymphocyte Progenitors and Maintains the B-2 Cell Fate

Fetal hepatic expression of 5-lipoxygenase activating protein is confined to colonizing hematopoietic cells

Functionally distinct hematopoietic stem cells modulate hematopoietic lineage potential during aging by a mechanism of clonal expansion

Gene expression analysis suggests that EBF-1 and PPARgamma2 induce adipogenesis of NIH-3T3 cells with similar efficiency and kinetics

Genomics based analysis of interactions between developing B-lymphocytes and stromal cells reveal complex interactions and two-way communication.

HOXA10 is a critical regulator for hematopoietic stem cells and erythroid/megakaryocyte development

IL-7 mediates Ebf-1-dependent lineage restriction in early lymphoid progenitors.

Identification of Flt3+ lympho-myeloid stem cells lacking erythro-megakaryocytic potential a revised road map for adult blood lineage commitment.

Identification of Lin(-)Sca1(+)kit(+)CD34(+)Flt3- short-term hematopoietic stem cells capable of rapidly reconstituting and rescuing myeloablated transplant recipients.

Immune status and inflammatory response differ locally and systemically in severe acute pancreatitis.

Induction ofID2Expression by Hypoxia-inducible Factor-1

Inhibition of p300/CBP by early B-cell factor

Interleukin-7-induced Stat-5 acts in synergy with Flt-3 signaling to stimulate expansion of hematopoietic progenitor cells.

Intrinsic inhibition of transcription factor E2A by HLH proteins ABF-1 and Id2 mediates reprogramming of neoplastic B cells in Hodgkin lymphoma

Lin28b controls a neonatal to adult switch in B cell positive selection

Lipopolysaccharide-induced fever depends on prostaglandin E2 production specifically in brain endothelial cells

Load and lock: the molecular mechanisms of B-lymphocyte commitment.

Loss of bHLH transcription factor E2A activity in primary effusion lymphoma confers resistance to apoptosis.

Loss- and gain-of-function analyses reveal targets of Pax6 in the developing mouse telencephalon.

Mice with an inactivated joining chain locus have perturbed IgM secretion

Molecular characterization of prospectively isolated multipotent mesenchymal progenitors provides new insight into the cellular identity of mesenchymal stem cells in mouse bone marrow.

Molecular evidence for hierarchical transcriptional lineage priming in fetal and adult stem cells and multipotent progenitors

Molecular profiling reveals distinct functional attributes of CD1d-restricted natural killer (NK) T cell subsets

Multilineage priming of enhancer repertoires precedes commitment to the B and myeloid cell lineages in hematopoietic progenitors.

Neuroblastoma and pre-B lymphoma cells share expression of key transcription factors but display tissue restricted target gene expression

New light on the biology and developmental potential of haematopoietic stem cells and progenitor cells.

Nuclear factor of activated T cells regulates osteopontin expression in arterial smooth muscle in response to diabetes-induced hyperglycemia

Oct proteins are qualitative rather than quantitative regulators of kappa transcription

Olf/EBF proteins are expressed in neuroblastoma cells: potential regulators of the Chromogranin A and SCG10 promoters

PAX5 is part of a functional transcription factor network targeted in lymphoid leukemia

Pearson correlation analysis of microarray data allows for the identification of genetic targets for early B-cell factor.

Permissive roles of hematopoietin and cytokine tyrosine kinase receptors in early T-cell development

Pioneering, chromatin remodeling, and epigenetic constraint in early T-cell gene regulation by SPI1 (PU.1)

Positive intergenic feedback circuitry, involving EBF1 and FOXO1, orchestrates B-cell fate

Predictive screening for regulators of conserved functional gene modules (gene batteries) in mammals

Primary mesenchymal stem and progenitor cells from bone marrow lack expression of CD44 protein

Probabilistic estimation of microarray data reliability and underlying gene expression

RNA analysis of B cell lines arrested at defined stages of differentiation allows for an approximation of gene expression patterns during B cell development.

Real-time analysis of Oct protein-octamer interaction and transcription complex assembly

Reduced repression of cytokine signaling ameliorates age‐induced decline in hematopoietic stem cell function ⬇️

Redundant Regulation of T Cell Differentiation and TCRα Gene Expression by the Transcription Factors LEF-1 and TCF-1 ⬇️

Shaping up a lineage--lessons from B lymphopoesis.

Single-cell analysis of early B-lymphocyte development suggests independent regulation of lineage specification and commitment in vivo.

Single-cell analysis of the common lymphoid progenitor compartment reveals functional and molecular heterogeneity.

Splenic B cells from Hymenolepis diminuta-infected mice ameliorate colitis independent of T cells and via cooperation with macrophages.

Stimulation of kappa transcription by a decamer-dependent, synergistic mechanism.

Structural Determination of Functional Domains in Early B-cell Factor (EBF) Family of Transcription Factors Reveals Similarities to Rel DNA-binding Proteins and a Novel Dimerization Motif

The CD53 and CEACAM-1 genes are genetic targets for early B cell factor.

The Cxcl12, periostin, and Ccl9 genes are direct targets for early B-cell factor in OP-9 stroma cells.

The EBF/Olf/Collier family of transcription factors: regulators of differentiation in cells originating from all three embryonal germ layers.

The Notch-2 gene is regulated by Wnt signaling in cultured colorectal cancer cells

The molecular signature of MDS stem cells supports a stem-cell origin of 5q myelodysplastic syndromes

The pT alpha promoter and enhancer are direct targets for transactivation by E box-binding proteins