Lista de obras - Arwyn T Jones - Dominio Público Uruguay

A role for the small GTPase Rab21 in the early endocytic pathway

artículo científico publicado en 2004

Arginine-rich peptides and their internalization mechanisms.

artículo científico publicado en 2007

BH3 helix-derived biophotonic nanoswitches regulate cytochrome c release in permeabilised cells ⬇️

artículo científico publicado el 1 de noviembre de 2013

Cell entry of cell penetrating peptides: tales of tails wagging dogs

artículo científico publicado en 2012

Cell-penetrating antimicrobial peptides - prospectives for targeting intracellular infections

artículo científico publicado en 2015

Cell-penetrating peptide sequence and modification dependent uptake and subcellular distribution of green florescent protein in different cell lines

scientific article published on 18 April 2019

Cellular internalization and distribution of arginine-rich peptides as a function of extracellular peptide concentration, serum, and plasma membrane associated proteoglycans

artículo científico publicado en 2008

Cellular uptake of arginine-rich peptides: roles for macropinocytosis and actin rearrangement

artículo científico publicado en 2004

Cellular uptake, distribution and cytotoxicity of the hydrophobic cell penetrating peptide sequence PFVYLI linked to the proapoptotic domain peptide PAD.

artículo científico publicado en 2009

Chemical synthesis of cell-permeable apoptotic peptides from in vivo produced proteins.

artículo científico publicado en 2011

Co-operative Membrane Disruption Between Cell-penetrating Peptide and Cargo: Implications for the Therapeutic Use of the Bcl-2 Converter Peptide D-NuBCP-9-r8 ⬇️

artículo científico publicado el 20 de septiembre de 2011

Comparison of the endocytic properties of linear and branched PEIs, and cationic PAMAM dendrimers in B16f10 melanoma cells.

artículo científico publicado en 2006

Contrasting roles for actin in the cellular uptake of cell penetrating peptide conjugates.

artículo científico publicado en 2018

Control of targeting ligand display by pH-responsive polymers on gold nanoparticles mediates selective entry into cancer cells.

artículo científico publicado en 2017

Cyanine dye mediated mitochondrial targeting enhances the anti-cancer activity of small-molecule cargoes

artículo científico publicado en 2020

Design, Synthesis and Evaluation of New Bioactive Oxadiazole Derivatives as Anticancer Agents Targeting Bcl-2

scientific article published on 26 November 2020

Design, synthesis and in vitro anticancer evaluation of 4,6-diamino-1,3,5-triazine-2-carbohydrazides and -carboxamides

artículo científico publicado en 2013

Differentiation of tumour-promoting stromal myofibroblasts by cancer exosomes.

artículo científico publicado en 2014

Distal phenylalanine modification for enhancing cellular delivery of fluorophores, proteins and quantum dots by cell penetrating peptides

artículo científico publicado en 2014

Disulfiram-induced cytotoxicity and endo-lysosomal sequestration of zinc in breast cancer cells

artículo científico publicado en 2014

Dynamic colocalization microscopy to characterize intracellular trafficking of nanomedicines

artículo científico publicado en 2011

Ecosystem type drives soil eukaryotic diversity and composition in Europe

artículo científico publicado en 2023

Effects of Na+/H+ exchanger inhibitors on subcellular localisation of endocytic organelles and intracellular dynamics of protein transduction domains HIV-TAT peptide and octaarginine

artículo científico publicado en 2006

Electrospray mass spectrometric evidence for the occurrence of two major variants in native pig pepsin A.

artículo científico publicado en 1996

Endocytosis, intracellular traffic and fate of cell penetrating peptide based conjugates and nanoparticles.

artículo científico publicado en 2013

Establishment of subcellular fractionation techniques to monitor the intracellular fate of polymer therapeutics I. Differential centrifugation fractionation B16F10 cells and use to study the intracellular fate of HPMA copolymer - doxorubicin.

artículo científico publicado en 2006

Flotillin-dependent endocytosis and a phagocytosis-like mechanism for cellular internalization of disulfide-based poly(amido amine)/DNA polyplexes.

artículo científico publicado en 2011

Fluorescence labelling of extracellular vesicles using a novel thiol-based strategy for quantitative analysis of cellular delivery and intracellular traffic

artículo científico publicado en 2017

Guanidine-Containing Molecular Transporters: Sorbitol-Based Transporters Show High Intracellular Selectivity toward Mitochondria

scholarly article by Kaustabh K. Maiti et al published 3 August 2007 in Angewandte Chemie International Edition

Human pepsin 3b peptide map sequence analysis, genotype and hydrophobic nature

scientific article published on 01 August 1993

Inhibition of Endosome Fusion by Wortmannin Persists in the Presence of Activated rab5 ⬇️

artículo científico publicado el 1 de febrero de 1998

Inhibition of calcium-independent mannose 6-phosphate receptor incorporation into trans-Golgi network-derived clathrin-coated vesicles by wortmannin

artículo científico publicado en 1997

Inhibition of in vitro endosomal vesicle fusion activity by aminoglycoside antibiotics

artículo científico publicado en 1998

Interleukin-4-inducing principle from Schistosoma mansoni eggs contains a functional C-terminal nuclear localization signal necessary for nuclear translocation in mammalian cells but not for its uptake.

artículo científico publicado en 2011

Intracellular Drug Delivery. Workshop Report from the 28th International Symposium on Controlled Release of Bioactive Materials, San Diego, 23–24 June 2001 ⬇️

artículo científico publicado el 1 de diciembre de 2001

Intracellular traffic and fate of protein transduction domains HIV-1 TAT peptide and octaarginine. Implications for their utilization as drug delivery vectors

artículo científico publicado en 2006

Intracellular trafficking pathways and drug delivery: fluorescence imaging of living and fixed cells.

artículo científico publicado en 2005

Investigating the mechanism of enhanced cytotoxicity of HPMA copolymer-Dox-AGM in breast cancer cells

artículo científico publicado en 2006

Involvement of the endosomal autoantigen EEA1 in homotypic fusion of early endosomes.

artículo científico publicado en 1998

Low concentration thresholds of plasma membranes for rapid energy-independent translocation of a cell-penetrating peptide

artículo científico publicado en 2009

Macropinocytosis: searching for an endocytic identity and role in the uptake of cell penetrating peptides

artículo científico publicado en 2007

Mycolic acids, a promising mycobacterial ligand for targeting of nanoencapsulated drugs in tuberculosis

artículo científico publicado en 2015

Nanomedicines for the Delivery of Biologics

scientific article published on 03 May 2019

Nanoparticle geometry and surface orientation influence mode of cellular uptake.

artículo científico publicado en 2013

Novel cis-selective and non-epimerisable C3 hydroxy azapodophyllotoxins targeting microtubules in cancer cells

artículo científico publicado en 2015

Novel monodisperse PEG-dendrons as new tools for targeted drug delivery: synthesis, characterization and cellular uptake

artículo científico publicado en 2006

Peptide maps of five human pepsin isoenzymes and other aspartic proteinases

scientific article published on 01 May 1992

Phosphatidylinositol 3-kinase activity is required for early endosome fusion.

artículo científico publicado en 1995

Phosphatidylinositol 3-kinase regulation of fluid phase endocytosis

artículo científico publicado en 1995

Post-pegylated lipoplexes are promising vehicles for gene delivery in RPE cells

artículo científico publicado en 2007

Preclinical development of bicyclic nucleoside analogues as potent and selective inhibitors of varicella zoster virus

artículo científico publicado en 2007

Rab7b modulates autophagic flux by interacting with Atg4B.

artículo científico publicado en 2017

Receptor Crosslinking: A General Method to Trigger Internalization and Lysosomal Targeting of Therapeutic Receptor:Ligand Complexes.

artículo científico publicado en 2015

Regulation of Early Endosome Fusion by Phospholipase D Activity ⬇️

artículo científico publicado el 18 de julio de 1997

Regulation of early-endosome dynamics by phosphatidylinositol 3-phosphate binding proteins.

artículo científico publicado en 1999

Regulation of endosome fusion.

artículo científico publicado en 1999

Switching of Macromolecular Ligand Display by Thermoresponsive Polymers Mediates Endocytosis of Multiconjugate Nanoparticles.

artículo científico publicado en 2018

Synthesis and evaluation of 3-(benzylthio)-5-(1H-indol-3-yl)-1,2,4-triazol-4-amines as Bcl-2 inhibitory anticancer agents

artículo científico publicado en 2013

Synthesis and evaluation of 5-(1H-indol-3-yl)-N-aryl-1,3,4-oxadiazol-2-amines as Bcl-2 inhibitory anticancer agents.

artículo científico publicado en 2016

Temperature-, concentration- and cholesterol-dependent translocation of L- and D-octa-arginine across the plasma and nuclear membrane of CD34+ leukaemia cells.

artículo científico publicado en 2007

The Role of BCA2 in the Endocytic Trafficking of EGFR and Significance as a Prognostic Biomarker in Cancer.

artículo científico publicado en 2016

The pH sensitive probe 5-(and-6)-carboxyl seminaphthorhodafluor is a substrate for the multidrug resistance-related protein MRP1.

artículo científico publicado en 2009

The use of inhibitors to study endocytic pathways of gene carriers: optimization and pitfalls

artículo científico publicado en 2009

Tuning the pH sensitivities of orthoester based compounds for drug delivery applications by simple chemical modification

artículo científico publicado en 2010

Understanding endocytic pathways and intracellular trafficking: a prerequisite for effective design of advanced drug delivery systems

artículo científico publicado en 2003

Virtual screening, SAR, and discovery of 5-(indole-3-yl)-2-[(2-nitrophenyl)amino] [1,3,4]-oxadiazole as a novel Bcl-2 inhibitor

artículo científico publicado en 2017

Visualizing Actin Architectures in Cells Incubated with Cell-Penetrating Peptides.

artículo científico publicado en 2015

siRNA Inhibition of Endocytic Pathways to Characterize the Cellular Uptake Mechanisms of Folate-Functionalized Glycol Chitosan Nanogels.

artículo científico publicado en 2015

siRNA and pharmacological inhibition of endocytic pathways to characterize the differential role of macropinocytosis and the actin cytoskeleton on cellular uptake of dextran and cationic cell penetrating peptides octaarginine (R8) and HIV-Tat.

artículo científico publicado en 2012

Lista de obras de Arwyn T Jones

A role for the small GTPase Rab21 in the early endocytic pathway

Arginine-rich peptides and their internalization mechanisms.

BH3 helix-derived biophotonic nanoswitches regulate cytochrome c release in permeabilised cells ⬇️

Cell entry of cell penetrating peptides: tales of tails wagging dogs

Cell-penetrating antimicrobial peptides - prospectives for targeting intracellular infections

Cell-penetrating peptide sequence and modification dependent uptake and subcellular distribution of green florescent protein in different cell lines

Cellular internalization and distribution of arginine-rich peptides as a function of extracellular peptide concentration, serum, and plasma membrane associated proteoglycans

Cellular uptake of arginine-rich peptides: roles for macropinocytosis and actin rearrangement

Cellular uptake, distribution and cytotoxicity of the hydrophobic cell penetrating peptide sequence PFVYLI linked to the proapoptotic domain peptide PAD.

Chemical synthesis of cell-permeable apoptotic peptides from in vivo produced proteins.

Co-operative Membrane Disruption Between Cell-penetrating Peptide and Cargo: Implications for the Therapeutic Use of the Bcl-2 Converter Peptide D-NuBCP-9-r8 ⬇️

Comparison of the endocytic properties of linear and branched PEIs, and cationic PAMAM dendrimers in B16f10 melanoma cells.

Contrasting roles for actin in the cellular uptake of cell penetrating peptide conjugates.

Control of targeting ligand display by pH-responsive polymers on gold nanoparticles mediates selective entry into cancer cells.

Cyanine dye mediated mitochondrial targeting enhances the anti-cancer activity of small-molecule cargoes

Design, Synthesis and Evaluation of New Bioactive Oxadiazole Derivatives as Anticancer Agents Targeting Bcl-2

Design, synthesis and in vitro anticancer evaluation of 4,6-diamino-1,3,5-triazine-2-carbohydrazides and -carboxamides

Differentiation of tumour-promoting stromal myofibroblasts by cancer exosomes.

Distal phenylalanine modification for enhancing cellular delivery of fluorophores, proteins and quantum dots by cell penetrating peptides

Disulfiram-induced cytotoxicity and endo-lysosomal sequestration of zinc in breast cancer cells

Dynamic colocalization microscopy to characterize intracellular trafficking of nanomedicines

Ecosystem type drives soil eukaryotic diversity and composition in Europe

Effects of Na+/H+ exchanger inhibitors on subcellular localisation of endocytic organelles and intracellular dynamics of protein transduction domains HIV-TAT peptide and octaarginine

Electrospray mass spectrometric evidence for the occurrence of two major variants in native pig pepsin A.

Endocytosis, intracellular traffic and fate of cell penetrating peptide based conjugates and nanoparticles.

Establishment of subcellular fractionation techniques to monitor the intracellular fate of polymer therapeutics I. Differential centrifugation fractionation B16F10 cells and use to study the intracellular fate of HPMA copolymer - doxorubicin.

Flotillin-dependent endocytosis and a phagocytosis-like mechanism for cellular internalization of disulfide-based poly(amido amine)/DNA polyplexes.

Fluorescence labelling of extracellular vesicles using a novel thiol-based strategy for quantitative analysis of cellular delivery and intracellular traffic

Guanidine-Containing Molecular Transporters: Sorbitol-Based Transporters Show High Intracellular Selectivity toward Mitochondria

Human pepsin 3b peptide map sequence analysis, genotype and hydrophobic nature

Inhibition of Endosome Fusion by Wortmannin Persists in the Presence of Activated rab5 ⬇️

Inhibition of calcium-independent mannose 6-phosphate receptor incorporation into trans-Golgi network-derived clathrin-coated vesicles by wortmannin

Inhibition of in vitro endosomal vesicle fusion activity by aminoglycoside antibiotics

Interleukin-4-inducing principle from Schistosoma mansoni eggs contains a functional C-terminal nuclear localization signal necessary for nuclear translocation in mammalian cells but not for its uptake.

Intracellular Drug Delivery. Workshop Report from the 28th International Symposium on Controlled Release of Bioactive Materials, San Diego, 23–24 June 2001 ⬇️

Intracellular traffic and fate of protein transduction domains HIV-1 TAT peptide and octaarginine. Implications for their utilization as drug delivery vectors

Intracellular trafficking pathways and drug delivery: fluorescence imaging of living and fixed cells.

Investigating the mechanism of enhanced cytotoxicity of HPMA copolymer-Dox-AGM in breast cancer cells

Involvement of the endosomal autoantigen EEA1 in homotypic fusion of early endosomes.

Low concentration thresholds of plasma membranes for rapid energy-independent translocation of a cell-penetrating peptide

Macropinocytosis: searching for an endocytic identity and role in the uptake of cell penetrating peptides

Mycolic acids, a promising mycobacterial ligand for targeting of nanoencapsulated drugs in tuberculosis

Nanomedicines for the Delivery of Biologics

Nanoparticle geometry and surface orientation influence mode of cellular uptake.

Novel cis-selective and non-epimerisable C3 hydroxy azapodophyllotoxins targeting microtubules in cancer cells

Novel monodisperse PEG-dendrons as new tools for targeted drug delivery: synthesis, characterization and cellular uptake

Peptide maps of five human pepsin isoenzymes and other aspartic proteinases

Phosphatidylinositol 3-kinase activity is required for early endosome fusion.

Phosphatidylinositol 3-kinase regulation of fluid phase endocytosis

Post-pegylated lipoplexes are promising vehicles for gene delivery in RPE cells

Preclinical development of bicyclic nucleoside analogues as potent and selective inhibitors of varicella zoster virus

Rab7b modulates autophagic flux by interacting with Atg4B.

Receptor Crosslinking: A General Method to Trigger Internalization and Lysosomal Targeting of Therapeutic Receptor:Ligand Complexes.

Regulation of Early Endosome Fusion by Phospholipase D Activity ⬇️

Regulation of early-endosome dynamics by phosphatidylinositol 3-phosphate binding proteins.

Regulation of endosome fusion.

Switching of Macromolecular Ligand Display by Thermoresponsive Polymers Mediates Endocytosis of Multiconjugate Nanoparticles.

Synthesis and evaluation of 3-(benzylthio)-5-(1H-indol-3-yl)-1,2,4-triazol-4-amines as Bcl-2 inhibitory anticancer agents

Synthesis and evaluation of 5-(1H-indol-3-yl)-N-aryl-1,3,4-oxadiazol-2-amines as Bcl-2 inhibitory anticancer agents.

Temperature-, concentration- and cholesterol-dependent translocation of L- and D-octa-arginine across the plasma and nuclear membrane of CD34+ leukaemia cells.

The Role of BCA2 in the Endocytic Trafficking of EGFR and Significance as a Prognostic Biomarker in Cancer.

The pH sensitive probe 5-(and-6)-carboxyl seminaphthorhodafluor is a substrate for the multidrug resistance-related protein MRP1.

The use of inhibitors to study endocytic pathways of gene carriers: optimization and pitfalls

Tuning the pH sensitivities of orthoester based compounds for drug delivery applications by simple chemical modification

Understanding endocytic pathways and intracellular trafficking: a prerequisite for effective design of advanced drug delivery systems

Virtual screening, SAR, and discovery of 5-(indole-3-yl)-2-[(2-nitrophenyl)amino] [1,3,4]-oxadiazole as a novel Bcl-2 inhibitor

Visualizing Actin Architectures in Cells Incubated with Cell-Penetrating Peptides.

siRNA Inhibition of Endocytic Pathways to Characterize the Cellular Uptake Mechanisms of Folate-Functionalized Glycol Chitosan Nanogels.

siRNA and pharmacological inhibition of endocytic pathways to characterize the differential role of macropinocytosis and the actin cytoskeleton on cellular uptake of dextran and cationic cell penetrating peptides octaarginine (R8) and HIV-Tat.