Lista de obras - Timofei S Zatsepin - Dominio Público Uruguay

1-Phenylethynylpyrene (PEPy) as a novel blue-emitting dye for qPCR assay

artículo científico publicado en 2016

A new fluorometric assay for the study of DNA-binding and 3'-processing activities of retroviral integrases and its use for screening of HIV-1 integrase inhibitors.

artículo científico publicado en 2012

A study on endonuclease BspD6I and its stimulus-responsive switching by modified oligonucleotides

artículo científico publicado en 2018

Analysis of DNA-protein interactions in complexes of transcription factor NF-kappaB with DNA.

artículo científico publicado en 2005

Anisotropic expansion of hepatocyte lumina enforced by apical bulkheads

artículo científico publicado en 2021

Application of sorting and next generation sequencing to study 5΄-UTR influence on translation efficiency in Escherichia coli

artículo científico publicado en 2016

Automated Solid-Phase Click Synthesis of Oligonucleotide Conjugates: From Small Molecules to Diverse N-Acetylgalactosamine Clusters.

artículo científico publicado en 2017

Biodegradable Polymeric Multilayer Capsules for Therapy of Lung Cancer

scientific article published on 27 January 2020

Characterization of HIV-1 integrase interaction with human Ku70 protein and initial implications for drug targeting.

artículo científico publicado en 2017

Chimeric bifunctional oligonucleotides as a novel tool to invade telomerase assembly.

artículo científico publicado en 2014

Clustered DNA Lesions Containing 5-Formyluracil and AP Site: Repair via the BER System ⬇️

artículo científico publicado el 6 de agosto de 2013

DNA -Motifs With Guanidino--Clamp Residues: The Counterplay Between Kinetics and Thermodynamics and Implications for the Design of pH Sensors

artículo científico publicado en 2019

DNA-methyltransferase SsoII as a bifunctional protein: features of the interaction with the promoter region of SsoII restriction-modification genes

artículo científico publicado en 2006

Dynamics of human telomerase RNA structure revealed by antisense oligonucleotide technique.

artículo científico publicado en 2013

Fine Tuning of Pyrene Excimer Fluorescence in Molecular Beacons by Alteration of the Monomer Structure.

artículo científico

Focused ultrasound-mediated fluorescence of composite microcapsules loaded with magnetite nanoparticles: In vitro and in vivo study

artículo científico publicado en 2019

Human Ku70 protein binds hairpin RNA and double stranded DNA through two different sites.

artículo científico publicado en 2016

Improved Electroactivity of Redox Probes onto Electropolymerized Azidomethyl-PEDOT: Enabling Click Chemistry for Advanced (Bio)Sensors

artículo científico publicado en 2021

Integrator is a key component of human telomerase RNA biogenesis

artículo científico publicado en 2019

Interaction of nucleotide excision repair factors XPC-HR23B, XPA, and RPA with damaged DNA.

artículo científico publicado en 2008

In Vivo RNAi-Mediated eIF3m Knockdown Affects Ribosome Biogenesis and Transcription but Has Limited Impact on mRNA-Specific Translation

artículo científico publicado en 2019

Lipid nanoparticles for targeted siRNA delivery - going from bench to bedside

artículo científico publicado en 2016

Metal ion CHElate-aSSisted LIGAtion (CHESS LIGA) for SNP detection on microarrays.

artículo científico publicado en 2009

Method for site-specific detection of m6A nucleoside presence in RNA based on high-resolution melting (HRM) analysis.

artículo científico publicado en 2013

Modification of Adenosine196 by Mettl3 Methyltransferase in the 5'-External Transcribed Spacer of 47S Pre-rRNA Affects rRNA Maturation

artículo científico publicado en 2020

Modulation of HIV-1 integrase activity by single-stranded oligonucleotides and their conjugates with eosin.

artículo científico publicado en 2011

Murine Long Noncoding RNA Morrbid Contributes in the Regulation of NRAS Splicing in Hepatocytes In Vitro

artículo científico publicado en 2020

NHEJ pathway is involved in post-integrational DNA repair due to Ku70 binding to HIV-1 integrase

artículo científico publicado en 2019

Novel Cluster and Monomer-Based GalNAc Structures Induce Effective Uptake of siRNAs in Vitro and in Vivo

artículo científico publicado en 2018

Novel homo Yin-Yang probes improve sensitivity in RT-qPCR detection of low copy HIV RNA

artículo científico publicado en 2018

Oligonucleotide Primers with G8AE-Clamp Modifications for RT-qPCR Detection of the Low-Copy dsRNA

artículo científico publicado en 2019

Oligonucleotide inhibitors of telomerase: prospects for anticancer therapy and diagnostics.

artículo científico publicado en 2015

Phenotypic Alteration of BMDM In Vitro Using Small Interfering RNA

artículo científico publicado en 2022

RT-qPCR Detection of Low-Copy HIV RNA with Yin-Yang Probes

artículo científico publicado en 2020

Red light-triggered photoreduction on a nucleic acid template

artículo científico publicado en 2020

Restriction Endonuclease SsoII with Photoregulated Activity—a “Molecular Gate” Approach ⬇️

artículo científico publicado el 20 de julio de 2011

Short Duplex Module Coupled to G-Quadruplexes Increases Fluorescence of Synthetic GFP Chromophore Analogues

artículo científico publicado en 2020

Silver(I)-mediated base pairing in parallel-stranded DNA involving the luminescent cytosine analog 1,3-diaza-2-oxophenoxazine

scientific article published on 01 July 2019

Solid- and solution-phase synthesis and application of R6G dual-labeled oligonucleotide probes

artículo científico publicado en 2015

Specificity of SNP detection with molecular beacons is improved by stem and loop separation with spacers

artículo científico publicado en 2017

Structure and function of the N-terminal domain of the yeast telomerase reverse transcriptase.

artículo científico publicado en 2017

Structure-Activity Relationship Studies of HIV-1 Integrase Oligonucleotide Inhibitors.

artículo científico publicado en 2011

Structure-based cross-linking of NF-kappaB p50 homodimer and decoy bearing a novel 2'-disulfide trapping site

artículo científico publicado en 2006

Structure-guided chemical modification of guide RNA enables potent non-viral in vivo genome editing.

artículo científico publicado en 2017

Suicide inactivation of covalent peroxidase-mimicking DNAzyme with hydrogen peroxide and its protection by a reductant substrate.

artículo científico publicado en 2016

Synthesis and biological evaluation of novel doxorubicin-containing ASGP-R-targeted drug-conjugates.

artículo científico publicado en 2017

Synthesis and biological evaluation of novel mono- and bivalent ASGP-R-targeted drug-conjugates

artículo científico publicado en 2017

Synthesis of (2'S)- and (2'R)-2'-deoxy-2'-[(2-methoxyethoxy)amino] pyrimidine nucleosides and oligonucleotides

artículo científico publicado en 2004

Synthesis of 2'-modified oligonucleotides containing aldehyde or ethylenediamine groups.

artículo científico publicado en 2003

Synthesis of oligonucleotides containing novel G-clamp analogue with C8-tethered group in phenoxazine ring: Implication to qPCR detection of the low-copy Kemerovo virus dsRNA.

artículo científico publicado en 2017

TERRA mimicking ssRNAs prevail over the DNA substrate for telomerase in vitro due to interactions with the alternative binding site

artículo científico

The Arg/N-Degron Pathway-A Potential Running Back in Fine-Tuning the Inflammatory Response?

artículo científico publicado en 2020

Toehold-Mediated Selective Assembly of Compact Discrete DNA Nanostructures

artículo científico publicado en 2020

Use of carbonyl group addition--elimination reactions for synthesis of nucleic acid conjugates.

artículo científico publicado en 2005

[Modification of nucleic acids using [3+2] dipolar cycloaddition of azides and alkynes]

artículo científico publicado en 2010

eIF4G2 balances its own mRNA translation via a PCBP2-based feedback loop

scientific article published on 22 April 2019

i-Clamp phenoxazine for the fine tuning of DNA i-motif stability

artículo científico publicado en 2018

lncRNA in the liver: Prospects for fundamental research and therapy by RNA interference

artículo científico publicado en 2016

mRNA-Based Therapeutics - Advances and Perspectives

artículo científico publicado en 2016

Lista de obras de Timofei S Zatsepin

1-Phenylethynylpyrene (PEPy) as a novel blue-emitting dye for qPCR assay

A new fluorometric assay for the study of DNA-binding and 3'-processing activities of retroviral integrases and its use for screening of HIV-1 integrase inhibitors.

A study on endonuclease BspD6I and its stimulus-responsive switching by modified oligonucleotides

Analysis of DNA-protein interactions in complexes of transcription factor NF-kappaB with DNA.

Anisotropic expansion of hepatocyte lumina enforced by apical bulkheads

Application of sorting and next generation sequencing to study 5΄-UTR influence on translation efficiency in Escherichia coli

Automated Solid-Phase Click Synthesis of Oligonucleotide Conjugates: From Small Molecules to Diverse N-Acetylgalactosamine Clusters.

Biodegradable Polymeric Multilayer Capsules for Therapy of Lung Cancer

Characterization of HIV-1 integrase interaction with human Ku70 protein and initial implications for drug targeting.

Chimeric bifunctional oligonucleotides as a novel tool to invade telomerase assembly.

Clustered DNA Lesions Containing 5-Formyluracil and AP Site: Repair via the BER System ⬇️

DNA -Motifs With Guanidino--Clamp Residues: The Counterplay Between Kinetics and Thermodynamics and Implications for the Design of pH Sensors

DNA-methyltransferase SsoII as a bifunctional protein: features of the interaction with the promoter region of SsoII restriction-modification genes

Dynamics of human telomerase RNA structure revealed by antisense oligonucleotide technique.

Fine Tuning of Pyrene Excimer Fluorescence in Molecular Beacons by Alteration of the Monomer Structure.

Focused ultrasound-mediated fluorescence of composite microcapsules loaded with magnetite nanoparticles: In vitro and in vivo study

Human Ku70 protein binds hairpin RNA and double stranded DNA through two different sites.

Improved Electroactivity of Redox Probes onto Electropolymerized Azidomethyl-PEDOT: Enabling Click Chemistry for Advanced (Bio)Sensors

Integrator is a key component of human telomerase RNA biogenesis

Interaction of nucleotide excision repair factors XPC-HR23B, XPA, and RPA with damaged DNA.

In Vivo RNAi-Mediated eIF3m Knockdown Affects Ribosome Biogenesis and Transcription but Has Limited Impact on mRNA-Specific Translation

Lipid nanoparticles for targeted siRNA delivery - going from bench to bedside

Metal ion CHElate-aSSisted LIGAtion (CHESS LIGA) for SNP detection on microarrays.

Method for site-specific detection of m6A nucleoside presence in RNA based on high-resolution melting (HRM) analysis.

Modification of Adenosine196 by Mettl3 Methyltransferase in the 5'-External Transcribed Spacer of 47S Pre-rRNA Affects rRNA Maturation

Modulation of HIV-1 integrase activity by single-stranded oligonucleotides and their conjugates with eosin.

Murine Long Noncoding RNA Morrbid Contributes in the Regulation of NRAS Splicing in Hepatocytes In Vitro

NHEJ pathway is involved in post-integrational DNA repair due to Ku70 binding to HIV-1 integrase

Novel Cluster and Monomer-Based GalNAc Structures Induce Effective Uptake of siRNAs in Vitro and in Vivo

Novel homo Yin-Yang probes improve sensitivity in RT-qPCR detection of low copy HIV RNA

Oligonucleotide Primers with G8AE-Clamp Modifications for RT-qPCR Detection of the Low-Copy dsRNA

Oligonucleotide inhibitors of telomerase: prospects for anticancer therapy and diagnostics.

Phenotypic Alteration of BMDM In Vitro Using Small Interfering RNA

RT-qPCR Detection of Low-Copy HIV RNA with Yin-Yang Probes

Red light-triggered photoreduction on a nucleic acid template

Restriction Endonuclease SsoII with Photoregulated Activity—a “Molecular Gate” Approach ⬇️

Short Duplex Module Coupled to G-Quadruplexes Increases Fluorescence of Synthetic GFP Chromophore Analogues

Silver(I)-mediated base pairing in parallel-stranded DNA involving the luminescent cytosine analog 1,3-diaza-2-oxophenoxazine

Solid- and solution-phase synthesis and application of R6G dual-labeled oligonucleotide probes

Specificity of SNP detection with molecular beacons is improved by stem and loop separation with spacers

Structure and function of the N-terminal domain of the yeast telomerase reverse transcriptase.

Structure-Activity Relationship Studies of HIV-1 Integrase Oligonucleotide Inhibitors.

Structure-based cross-linking of NF-kappaB p50 homodimer and decoy bearing a novel 2'-disulfide trapping site

Structure-guided chemical modification of guide RNA enables potent non-viral in vivo genome editing.

Suicide inactivation of covalent peroxidase-mimicking DNAzyme with hydrogen peroxide and its protection by a reductant substrate.

Synthesis and biological evaluation of novel doxorubicin-containing ASGP-R-targeted drug-conjugates.

Synthesis and biological evaluation of novel mono- and bivalent ASGP-R-targeted drug-conjugates

Synthesis of (2'S)- and (2'R)-2'-deoxy-2'-[(2-methoxyethoxy)amino] pyrimidine nucleosides and oligonucleotides

Synthesis of 2'-modified oligonucleotides containing aldehyde or ethylenediamine groups.

Synthesis of oligonucleotides containing novel G-clamp analogue with C8-tethered group in phenoxazine ring: Implication to qPCR detection of the low-copy Kemerovo virus dsRNA.

TERRA mimicking ssRNAs prevail over the DNA substrate for telomerase in vitro due to interactions with the alternative binding site

The Arg/N-Degron Pathway-A Potential Running Back in Fine-Tuning the Inflammatory Response?

Toehold-Mediated Selective Assembly of Compact Discrete DNA Nanostructures

Use of carbonyl group addition--elimination reactions for synthesis of nucleic acid conjugates.

[Modification of nucleic acids using [3+2] dipolar cycloaddition of azides and alkynes]

eIF4G2 balances its own mRNA translation via a PCBP2-based feedback loop

i-Clamp phenoxazine for the fine tuning of DNA i-motif stability

lncRNA in the liver: Prospects for fundamental research and therapy by RNA interference

mRNA-Based Therapeutics - Advances and Perspectives