Lista de obras - Megan L O'Mara - Dominio Público Uruguay

A Unique Sequence Is Essential for Efficient Multidrug Efflux Function of the MtrD Protein of <i>Neisseria gonorrhoeae</i>

artículo científico publicado en 2021

A model of the glycine receptor deduced from Brownian dynamics studies

artículo científico publicado en 2003

A multifunctional surfactant catalyst inspired by hydrolases

scientific article published on 01 April 2020

A potential new, stable state of the E-cadherin strand-swapped dimer in solution

artículo científico publicado en 2017

ABC transporters: a riddle wrapped in a mystery inside an enigma

artículo científico publicado en 2009

ATP-binding cassette transporters in Escherichia coli

artículo científico publicado en 2008

AdcA and AdcAII employ distinct zinc acquisition mechanisms and contribute additively to zinc homeostasis in Streptococcus pneumoniae

artículo científico publicado en 2014

Capturing the Dynamics of a Spring-Loaded Protein.

artículo científico publicado en 2017

Characterizing the conformational dynamics of metal-free PsaA using molecular dynamics simulations and electron paramagnetic resonance spectroscopy

artículo científico publicado en 2015

Comparing Nonbonded Metal Ion Models in the Divalent Cation Binding Protein PsaA

artículo científico publicado en 2020

Computer simulations of ABC transporter components

artículo científico publicado en 2006

Conduction mechanisms of chloride ions in ClC-type channels

artículo científico publicado en 2004

Correction: Identification of a 3rd Na+ Binding Site of the Glycine Transporter, GlyT2.

artículo científico publicado en 2016

Cytosolic region of TM6 in P-glycoprotein: topographical analysis and functional perturbation by site directed labeling

artículo científico publicado en 2008

Dysregulation of transition metal ion homeostasis is the molecular basis for cadmium toxicity in Streptococcus pneumoniae

artículo científico publicado en 2015

Effect of Poly(ethylene glycol) (PEG) Spacers on the Conformational Properties of Small Peptides: A Molecular Dynamics Study

artículo científico publicado en 2010

Effect of the Force Field on Molecular Dynamics Simulations of the Multidrug Efflux Protein P-Glycoprotein

scientific article published on 10 September 2021

Homology model of the GABAA receptor examined using Brownian dynamics

artículo científico publicado en 2005

Hydrogen bond-Driven Self-Assembly between Amidinium Cations and Carboxylate Anions: A Combined Molecular Dynamics, NMR Spectroscopy, and Single Crystal X-ray Diffraction Study

artículo científico publicado en 2017

Hydrophobic Shielding Drives Catalysis of Hydride Transfer in a Family of F420H2-Dependent Enzymes

artículo científico publicado en 2016

Identification of Possible Binding Sites for Morphine and Nicardipine on the Multidrug Transporter P-Glycoprotein Using Umbrella Sampling Techniques

artículo científico publicado en 2015

Identification of a 3rd Na+ Binding Site of the Glycine Transporter, GlyT2.

artículo científico publicado en 2016

Identification of an allosteric binding site on the human glycine transporter, GlyT2, for bioactive lipid analgesics

artículo científico publicado en 2019

Imperfect coordination chemistry facilitates metal ion release in the Psa permease

artículo científico publicado en 2014

Intestinal peptidases form functional complexes with the neutral amino acid transporter B0AT1 ⬇️

artículo científico publicado el 15 de agosto de 2012

Is protein structure enough? A review of the role of lipids in SLC6 transporter function

artículo científico publicado en 2018

Lipid-Based Inhibitors Act Directly on GlyT2

scientific article published on 17 December 2018

Location of contact residues in pharmacologically distinct drug binding sites on P-glycoprotein

artículo científico publicado en 2016

Mechanism and putative structure of B(0)-like neutral amino acid transporters.

artículo científico publicado en 2006

Mechanism of activation of protein kinase JAK2 by the growth hormone receptor

artículo científico publicado en 2014

Method for Developing Optical Sensors Using a Synthetic Dye-Fluorescent Protein FRET Pair and Computational Modeling and Assessment

artículo científico publicado en 2017

Molecular Determinants for Substrate Interactions with the Glycine Transporter GlyT2.

artículo científico publicado en 2017

Molecular basis for the interaction of the mammalian amino acid transporters B0AT1 and B0AT3 with their ancillary protein collectrin

artículo científico publicado en 2015

Multidrug Resistance in Neisseria gonorrhoeae: Identification of Functionally Important Residues in the MtrD Efflux Protein

scientific article published on 19 November 2019

Non-linear intramolecular interactions and voltage sensitivity of a KV1 family potassium channel from Polyorchis penicillatus (Eschscholtz 1829).

artículo científico publicado en 2008

Orientation of -Conotoxin PIIIA in a Sodium Channel Vestibule, Based on Voltage Dependence of Its Binding

article

P-glycoprotein models of the apo and ATP-bound states based on homology with Sav1866 and MalK

scientific article published on 07 August 2007

Pore structure controls stability and molecular flux in engineered protein cages

artículo científico publicado en 2022

Probing the Pharmacological Binding Sites of P-Glycoprotein Using Umbrella Sampling Simulations

scientific article published on 02 January 2019

PsiRESP: calculating RESP charges with Psi4

scientific article published on 04 May 2022

Residue G346 in transmembrane segment six is involved in inter-domain communication in P-glycoprotein

artículo científico publicado en 2007

Rv2074 is a novel F420 H2 -dependent biliverdin reductase in Mycobacterium tuberculosis

artículo científico publicado en 2016

Simple Design of an Enzyme-Inspired Supported Catalyst Based on a Catalytic Triad

Structural and dynamic perspectives on the promiscuous transport activity of P-glycoprotein

artículo científico publicado en 2016

Structural characterization of two metastable ATP-bound states of P-glycoprotein

artículo científico publicado en 2014

Structure of a lipid A phosphoethanolamine transferase suggests how conformational changes govern substrate binding

artículo científico publicado en 2017

Structure-based interpretation of the mutagenesis database for the nucleotide binding domains of P-glycoprotein.

artículo científico publicado en 2007

Synthetically controlling dendrimer flexibility improves delivery of large plasmid DNA.

scientific article published on 27 January 2017

The Effect of Environment on the Structure of a Membrane Protein: P-Glycoprotein under Physiological Conditions

artículo científico publicado en 2012

The central cavity of ABCB1 undergoes alternating access during ATP hydrolysis

artículo científico publicado en 2014

The effect of environment on the recognition and binding of vancomycin to native and resistant forms of lipid II.

artículo científico publicado en 2011

The effects of oxidised phospholipids and cholesterol on the biophysical properties of POPC bilayers

artículo científico publicado en 2018

The mechanism of ABC transporters: general lessons from structural and functional studies of an antigenic peptide transporter.

artículo científico publicado en 2009

The reliability of molecular dynamics simulations of the multidrug transporter P-glycoprotein in a membrane environment.

artículo científico publicado en 2018

The ryanodine receptor store-sensing gate controls Ca2+ waves and Ca2+-triggered arrhythmias

artículo científico publicado en 2014

The structural basis of bacterial manganese import

artículo científico publicado en 2021

Transmembrane helix 12 modulates progression of the ATP catalytic cycle in ABCB1.

artículo científico publicado en 2009

Transmembrane helix 12 plays a pivotal role in coupling energy provision and drug binding in ABCB1.

artículo científico publicado en 2010

Understanding the Link between Lipid Diversity and the Biophysical Properties of the Neuronal Plasma Membrane

artículo científico publicado en 2020

Understanding the accumulation of P-glycoprotein substrates within cells: The effect of cholesterol on membrane partitioning.

artículo científico publicado en 2015

Vancomycin: ligand recognition, dimerization and super-complex formation

artículo científico publicado en 2013

Lista de obras de Megan L O'Mara

A Unique Sequence Is Essential for Efficient Multidrug Efflux Function of the MtrD Protein of <i>Neisseria gonorrhoeae</i>

A model of the glycine receptor deduced from Brownian dynamics studies

A multifunctional surfactant catalyst inspired by hydrolases

A potential new, stable state of the E-cadherin strand-swapped dimer in solution

ABC transporters: a riddle wrapped in a mystery inside an enigma

ATP-binding cassette transporters in Escherichia coli

AdcA and AdcAII employ distinct zinc acquisition mechanisms and contribute additively to zinc homeostasis in Streptococcus pneumoniae

Capturing the Dynamics of a Spring-Loaded Protein.

Characterizing the conformational dynamics of metal-free PsaA using molecular dynamics simulations and electron paramagnetic resonance spectroscopy

Comparing Nonbonded Metal Ion Models in the Divalent Cation Binding Protein PsaA

Computer simulations of ABC transporter components

Conduction mechanisms of chloride ions in ClC-type channels

Correction: Identification of a 3rd Na+ Binding Site of the Glycine Transporter, GlyT2.

Cytosolic region of TM6 in P-glycoprotein: topographical analysis and functional perturbation by site directed labeling

Dysregulation of transition metal ion homeostasis is the molecular basis for cadmium toxicity in Streptococcus pneumoniae

Effect of Poly(ethylene glycol) (PEG) Spacers on the Conformational Properties of Small Peptides: A Molecular Dynamics Study

Effect of the Force Field on Molecular Dynamics Simulations of the Multidrug Efflux Protein P-Glycoprotein

Homology model of the GABAA receptor examined using Brownian dynamics

Hydrogen bond-Driven Self-Assembly between Amidinium Cations and Carboxylate Anions: A Combined Molecular Dynamics, NMR Spectroscopy, and Single Crystal X-ray Diffraction Study

Hydrophobic Shielding Drives Catalysis of Hydride Transfer in a Family of F420H2-Dependent Enzymes

Identification of Possible Binding Sites for Morphine and Nicardipine on the Multidrug Transporter P-Glycoprotein Using Umbrella Sampling Techniques

Identification of a 3rd Na+ Binding Site of the Glycine Transporter, GlyT2.

Identification of an allosteric binding site on the human glycine transporter, GlyT2, for bioactive lipid analgesics

Imperfect coordination chemistry facilitates metal ion release in the Psa permease

Intestinal peptidases form functional complexes with the neutral amino acid transporter B0AT1 ⬇️

Is protein structure enough? A review of the role of lipids in SLC6 transporter function

Lipid-Based Inhibitors Act Directly on GlyT2

Location of contact residues in pharmacologically distinct drug binding sites on P-glycoprotein

Mechanism and putative structure of B(0)-like neutral amino acid transporters.

Mechanism of activation of protein kinase JAK2 by the growth hormone receptor

Method for Developing Optical Sensors Using a Synthetic Dye-Fluorescent Protein FRET Pair and Computational Modeling and Assessment

Molecular Determinants for Substrate Interactions with the Glycine Transporter GlyT2.

Molecular basis for the interaction of the mammalian amino acid transporters B0AT1 and B0AT3 with their ancillary protein collectrin

Multidrug Resistance in Neisseria gonorrhoeae: Identification of Functionally Important Residues in the MtrD Efflux Protein

Non-linear intramolecular interactions and voltage sensitivity of a KV1 family potassium channel from Polyorchis penicillatus (Eschscholtz 1829).

Orientation of -Conotoxin PIIIA in a Sodium Channel Vestibule, Based on Voltage Dependence of Its Binding

P-glycoprotein models of the apo and ATP-bound states based on homology with Sav1866 and MalK

Pore structure controls stability and molecular flux in engineered protein cages

Probing the Pharmacological Binding Sites of P-Glycoprotein Using Umbrella Sampling Simulations

PsiRESP: calculating RESP charges with Psi4

Residue G346 in transmembrane segment six is involved in inter-domain communication in P-glycoprotein

Rv2074 is a novel F420 H2 -dependent biliverdin reductase in Mycobacterium tuberculosis

Simple Design of an Enzyme-Inspired Supported Catalyst Based on a Catalytic Triad

Structural and dynamic perspectives on the promiscuous transport activity of P-glycoprotein

Structural characterization of two metastable ATP-bound states of P-glycoprotein

Structure of a lipid A phosphoethanolamine transferase suggests how conformational changes govern substrate binding

Structure-based interpretation of the mutagenesis database for the nucleotide binding domains of P-glycoprotein.

Synthetically controlling dendrimer flexibility improves delivery of large plasmid DNA.

The Effect of Environment on the Structure of a Membrane Protein: P-Glycoprotein under Physiological Conditions

The central cavity of ABCB1 undergoes alternating access during ATP hydrolysis

The effect of environment on the recognition and binding of vancomycin to native and resistant forms of lipid II.

The effects of oxidised phospholipids and cholesterol on the biophysical properties of POPC bilayers

The mechanism of ABC transporters: general lessons from structural and functional studies of an antigenic peptide transporter.

The reliability of molecular dynamics simulations of the multidrug transporter P-glycoprotein in a membrane environment.

The ryanodine receptor store-sensing gate controls Ca2+ waves and Ca2+-triggered arrhythmias

The structural basis of bacterial manganese import

Transmembrane helix 12 modulates progression of the ATP catalytic cycle in ABCB1.

Transmembrane helix 12 plays a pivotal role in coupling energy provision and drug binding in ABCB1.

Understanding the Link between Lipid Diversity and the Biophysical Properties of the Neuronal Plasma Membrane

Understanding the accumulation of P-glycoprotein substrates within cells: The effect of cholesterol on membrane partitioning.

Vancomycin: ligand recognition, dimerization and super-complex formation