Lista de obras - Bryan Maloney - Dominio Público Uruguay

A serine protease KLK8 emerges as a regulator of regulators in memory: Microtubule protein dependent neuronal morphology and PKA-CREB signaling.

artículo científico publicado en 2018

Alzheimer's disease (AD)-like pathology in aged monkeys after infantile exposure to environmental metal lead (Pb): evidence for a developmental origin and environmental link for AD.

artículo científico publicado en 2008

BACE1 gene promoter is differentially regulated: detection of a novel promoter region for its cell type-specific regulation

artículo científico publicado en 2006

Challenges in creating a vaccine to prevent hepatitis E.

artículo científico publicado en 2005

Characterization of the APP proximal promoter and 5'-untranslated regions: identification of cell type-specific domains and implications in APP gene expression and Alzheimer's disease.

artículo científico publicado en 2005

Characterization of the human beta-secretase 2 (BACE2) 5'-flanking region: identification of a 268-bp region as the basal BACE2 promoter

artículo científico publicado en 2006

Characterization of two APP gene promoter polymorphisms that appear to influence risk of late-onset Alzheimer's disease

artículo científico publicado en 2004

Construction of recombinant avian infectious laryngotracheitis virus expressing the beta-galactosidase gene and DNA sequencing of the insertion region

artículo científico publicado en 1994

Copper depletion down-regulates expression of the Alzheimer's disease amyloid-beta precursor protein gene

artículo científico publicado en 2004

Correction: Rivastigmine modifies the α-secretase pathway and potentially early Alzheimer's disease

artículo científico publicado en 2020

Development and validation of the high-quality 'rapid method for swab' to genotype the HTTLPR serotonin transporter (SLC6A4) promoter polymorphism

artículo científico publicado en 2009

Do epigenetic pathways initiate late onset Alzheimer disease (LOAD): towards a new paradigm.

artículo científico publicado en 2012

Early-emerging cognitive vulnerability to depression and the serotonin transporter promoter region polymorphism

scientific article published on 04 September 2007

Early-life events may trigger biochemical pathways for Alzheimer's disease: the "LEARn" model.

artículo científico publicado en 2008

Epigenetics of dementia: understanding the disease as a transformation rather than a state.

artículo científico publicado en 2016

Exposure to lead and the developmental origin of oxidative DNA damage in the aging brain

artículo científico publicado en 2006

Functional activity of the novel Alzheimer's amyloid β-peptide interacting domain (AβID) in the APP and BACE1 promoter sequences and implications in activating apoptotic genes and in amyloidogenesis

artículo científico publicado en 2011

Functional characterization of the 5' flanking region of the BACE gene: identification of a 91 bp fragment involved in basal level of BACE promoter expression

artículo científico publicado en 2004

Functional characterization of three single-nucleotide polymorphisms present in the human APOE promoter sequence: Differential effects in neuronal cells and on DNA-protein interactions

artículo científico publicado en 2010

Functional domains of the BACE1 and BACE2 promoters and mechanisms of transcriptional suppression of the BACE2 promoter in normal neuronal cells

artículo científico publicado en 2006

Gene structure and organization of the human beta-secretase (BACE) promoter.

artículo científico publicado en 2004

Gene × environment interaction by a longitudinal epigenome-wide association study (LEWAS) overcomes limitations of genome-wide association study (GWAS)

artículo científico publicado en 2012

Genes are not our destiny: the somatic epitype bridges between the genotype and the phenotype

article

How and when environmental agents and dietary factors affect the course of Alzheimer's disease: the "LEARn" model (latent early-life associated regulation) may explain the triggering of AD.

artículo científico publicado en 2007

How autism and Alzheimer's disease are TrAPPed

artículo científico publicado en 2020

Important differences between human and mouse APOE gene promoters: limitation of mouse APOE model in studying Alzheimer's disease.

artículo científico publicado en 2007

Late-onset Alzheimer's disease, heating up and foxed by several proteins: pathomolecular effects of the aging process.

artículo científico publicado en 2014

Latent consequences of early-life lead (Pb) exposure and the future: Addressing the Pb crisis

scientific article published on 05 July 2018

Lessons from a BACE1 inhibitor trial: off-site but not off base.

artículo científico publicado en 2014

Lifespan profiles of Alzheimer's disease-associated genes and products in monkeys and mice

artículo científico publicado en 2009

Lithium alters expression of RNAs in a type-specific manner in differentiated human neuroblastoma neuronal cultures, including specific genes involved in Alzheimer's disease

scientific article published on 04 December 2019

M1 muscarinic receptor is a key target of neuroprotection, neuroregeneration and memory recovery by i-Extract from Withania somnifera

scientific article published on 30 September 2019

Mechanism of promoter activity of the beta-amyloid precursor protein gene in different cell lines: identification of a specific 30 bp fragment in the proximal promoter region

artículo científico publicado en 2004

MicroRNA-298 reduces levels of human amyloid-β precursor protein (APP), β-site APP-converting enzyme 1 (BACE1) and specific tau protein moieties

artículo científico publicado en 2020

NF-(kappa)B mediates amyloid beta peptide-stimulated activity of the human apolipoprotein E gene promoter in human astroglial cells

artículo científico publicado en 2005

Novel roles of amyloid-beta precursor protein metabolites in fragile X syndrome and autism.

artículo científico publicado en 2016

Novel upregulation of amyloid-β precursor protein (APP) by microRNA-346 via targeting of APP mRNA 5'-untranslated region: Implications in Alzheimer's disease

scientific article published on 23 November 2018

Presence of a "CAGA box" in the APP gene unique to amyloid plaque-forming species and absent in all APLP-1/2 genes: implications in Alzheimer's disease

artículo científico publicado en 2004

PuF, an antimetastatic and developmental signaling protein, interacts with the Alzheimer's amyloid-β precursor protein via a tissue-specific proximal regulatory element (PRE)

artículo científico publicado en 2013

Rivastigmine modifies the α-secretase pathway and potentially early Alzheimer's disease

scientific article published on 03 February 2020

Spurious polyadenylation of Norovirus Narita 104 capsid protein mRNA in transgenic plants.

artículo científico publicado en 2011

Structural and functional characterization of H2 haplotype MAPT promoter: unique neurospecific domains and a hypoxia-inducible element would enhance rationally targeted tauopathy research for Alzheimer's disease.

artículo científico publicado en 2012

Taking down the unindicted co-conspirators of amyloid beta-peptide-mediated neuronal death: shared gene regulation of BACE1 and APP genes interacting with CREB, Fe65 and YY1 transcription factors

artículo científico publicado en 2006

Temperamental fearfulness in childhood and the serotonin transporter promoter region polymorphism: a multimethod association study

artículo científico publicado en 2007

The "LEARn" (Latent Early-life Associated Regulation) model integrates environmental risk factors and the developmental basis of Alzheimer's disease, and proposes remedial steps

artículo científico publicado en 2010

The Alzheimer's amyloid β-peptide (Aβ) binds a specific DNA Aβ-interacting domain (AβID) in the APP, BACE1, and APOE promoters in a sequence-specific manner: characterizing a new regulatory motif

artículo científico publicado en 2011

The LEARn model: an epigenetic explanation for idiopathic neurobiological diseases

artículo científico publicado en 2009

The experimental Alzheimer's disease drug posiphen [(+)-phenserine] lowers amyloid-beta peptide levels in cell culture and mice.

artículo científico publicado en 2006

Transcriptional regulation of beta-secretase by p25/cdk5 leads to enhanced amyloidogenic processing

artículo científico publicado en 2008

Transgenerational latent early-life associated regulation unites environment and genetics across generations

artículo científico publicado en 2016

Virus-like particle expression and assembly in plants: hepatitis B and Norwalk viruses

artículo científico publicado en 2005

Lista de obras de Bryan Maloney

A serine protease KLK8 emerges as a regulator of regulators in memory: Microtubule protein dependent neuronal morphology and PKA-CREB signaling.

Alzheimer's disease (AD)-like pathology in aged monkeys after infantile exposure to environmental metal lead (Pb): evidence for a developmental origin and environmental link for AD.

BACE1 gene promoter is differentially regulated: detection of a novel promoter region for its cell type-specific regulation

Challenges in creating a vaccine to prevent hepatitis E.

Characterization of the APP proximal promoter and 5'-untranslated regions: identification of cell type-specific domains and implications in APP gene expression and Alzheimer's disease.

Characterization of the human beta-secretase 2 (BACE2) 5'-flanking region: identification of a 268-bp region as the basal BACE2 promoter

Characterization of two APP gene promoter polymorphisms that appear to influence risk of late-onset Alzheimer's disease

Construction of recombinant avian infectious laryngotracheitis virus expressing the beta-galactosidase gene and DNA sequencing of the insertion region

Copper depletion down-regulates expression of the Alzheimer's disease amyloid-beta precursor protein gene

Correction: Rivastigmine modifies the α-secretase pathway and potentially early Alzheimer's disease

Development and validation of the high-quality 'rapid method for swab' to genotype the HTTLPR serotonin transporter (SLC6A4) promoter polymorphism

Do epigenetic pathways initiate late onset Alzheimer disease (LOAD): towards a new paradigm.

Early-emerging cognitive vulnerability to depression and the serotonin transporter promoter region polymorphism

Early-life events may trigger biochemical pathways for Alzheimer's disease: the "LEARn" model.

Epigenetics of dementia: understanding the disease as a transformation rather than a state.

Exposure to lead and the developmental origin of oxidative DNA damage in the aging brain

Functional activity of the novel Alzheimer's amyloid β-peptide interacting domain (AβID) in the APP and BACE1 promoter sequences and implications in activating apoptotic genes and in amyloidogenesis

Functional characterization of the 5' flanking region of the BACE gene: identification of a 91 bp fragment involved in basal level of BACE promoter expression

Functional characterization of three single-nucleotide polymorphisms present in the human APOE promoter sequence: Differential effects in neuronal cells and on DNA-protein interactions

Functional domains of the BACE1 and BACE2 promoters and mechanisms of transcriptional suppression of the BACE2 promoter in normal neuronal cells

Gene structure and organization of the human beta-secretase (BACE) promoter.

Gene × environment interaction by a longitudinal epigenome-wide association study (LEWAS) overcomes limitations of genome-wide association study (GWAS)

Genes are not our destiny: the somatic epitype bridges between the genotype and the phenotype

How and when environmental agents and dietary factors affect the course of Alzheimer's disease: the "LEARn" model (latent early-life associated regulation) may explain the triggering of AD.

How autism and Alzheimer's disease are TrAPPed

Important differences between human and mouse APOE gene promoters: limitation of mouse APOE model in studying Alzheimer's disease.

Late-onset Alzheimer's disease, heating up and foxed by several proteins: pathomolecular effects of the aging process.

Latent consequences of early-life lead (Pb) exposure and the future: Addressing the Pb crisis

Lessons from a BACE1 inhibitor trial: off-site but not off base.

Lifespan profiles of Alzheimer's disease-associated genes and products in monkeys and mice

Lithium alters expression of RNAs in a type-specific manner in differentiated human neuroblastoma neuronal cultures, including specific genes involved in Alzheimer's disease

M1 muscarinic receptor is a key target of neuroprotection, neuroregeneration and memory recovery by i-Extract from Withania somnifera

Mechanism of promoter activity of the beta-amyloid precursor protein gene in different cell lines: identification of a specific 30 bp fragment in the proximal promoter region

MicroRNA-298 reduces levels of human amyloid-β precursor protein (APP), β-site APP-converting enzyme 1 (BACE1) and specific tau protein moieties

NF-(kappa)B mediates amyloid beta peptide-stimulated activity of the human apolipoprotein E gene promoter in human astroglial cells

Novel roles of amyloid-beta precursor protein metabolites in fragile X syndrome and autism.

Novel upregulation of amyloid-β precursor protein (APP) by microRNA-346 via targeting of APP mRNA 5'-untranslated region: Implications in Alzheimer's disease

Presence of a "CAGA box" in the APP gene unique to amyloid plaque-forming species and absent in all APLP-1/2 genes: implications in Alzheimer's disease

PuF, an antimetastatic and developmental signaling protein, interacts with the Alzheimer's amyloid-β precursor protein via a tissue-specific proximal regulatory element (PRE)

Rivastigmine modifies the α-secretase pathway and potentially early Alzheimer's disease

Spurious polyadenylation of Norovirus Narita 104 capsid protein mRNA in transgenic plants.

Structural and functional characterization of H2 haplotype MAPT promoter: unique neurospecific domains and a hypoxia-inducible element would enhance rationally targeted tauopathy research for Alzheimer's disease.

Taking down the unindicted co-conspirators of amyloid beta-peptide-mediated neuronal death: shared gene regulation of BACE1 and APP genes interacting with CREB, Fe65 and YY1 transcription factors

Temperamental fearfulness in childhood and the serotonin transporter promoter region polymorphism: a multimethod association study

The "LEARn" (Latent Early-life Associated Regulation) model integrates environmental risk factors and the developmental basis of Alzheimer's disease, and proposes remedial steps

The Alzheimer's amyloid β-peptide (Aβ) binds a specific DNA Aβ-interacting domain (AβID) in the APP, BACE1, and APOE promoters in a sequence-specific manner: characterizing a new regulatory motif

The LEARn model: an epigenetic explanation for idiopathic neurobiological diseases

The experimental Alzheimer's disease drug posiphen [(+)-phenserine] lowers amyloid-beta peptide levels in cell culture and mice.

Transcriptional regulation of beta-secretase by p25/cdk5 leads to enhanced amyloidogenic processing

Transgenerational latent early-life associated regulation unites environment and genetics across generations

Virus-like particle expression and assembly in plants: hepatitis B and Norwalk viruses