Lista de obras - Bernard Lopez - Dominio Público Uruguay

53BP1 Protects against CtIP-Dependent Capture of Ectopic Chromosomal Sequences at the Junction of Distant Double-Strand Breaks

artículo científico publicado en 2016

A homologous recombination defect affects replication-fork progression in mammalian cells.

artículo científico publicado en 2007

A nonsense mutation in the DNA repair factor Hebo causes mild bone marrow failure and microcephaly.

artículo científico publicado en 2016

A role for BLM in double-strand break repair pathway choice: prevention of CtIP/Mre11-mediated alternative nonhomologous end-joining.

artículo científico publicado en 2013

A threshold of endogenous stress is required to engage cellular response to protect against mutagenesis.

artículo científico publicado en 2016

AKT1 represses gene conversion induced by different genotoxic stresses and induces supernumerary centrosomes and aneuploidy in hamster ovary cells.

artículo científico publicado en 2009

AKT1/BRCA1 in the control of homologous recombination and genetic stability: the missing link between hereditary and sporadic breast cancers ⬇️

artículo científico publicado el 1 de diciembre de 2010

Alpha-thalassemia haplotypes in the Algerian population

artículo científico publicado en 1987

An in vitro enzymatic assay coupled to proteomics analysis reveals a new DNA processing activity for Ewing sarcoma and TAF(II)68 proteins.

artículo científico publicado en 2006

An xrcc4 defect or Wortmannin stimulates homologous recombination specifically induced by double-strand breaks in mammalian cells.

artículo científico publicado en 2002

Analysis of intrachromosomal homologous recombination in mammalian cell, using tandem repeat sequences.

artículo científico publicado en 1999

Bax and Bid, two proapoptotic Bcl-2 family members, inhibit homologous recombination, independently of apoptosis regulation.

artículo científico publicado en 2006

Bcl-2 inhibits nuclear homologous recombination by localizing BRCA1 to the endomembranes

artículo científico publicado en 2011

Cellular uptake pathways of sepiolite nanofibers and DNA transfection improvement.

artículo científico publicado en 2017

Characterization of homologous recombination induced by replication inhibition in mammalian cells

artículo científico publicado en 2001

Characterization of mammalian RAD51 double strand break repair using non-lethal dominant-negative forms.

artículo científico publicado en 2000

Characterization of two nuclear mammalian homologous DNA-pairing activities that do not require associated exonuclease activity.

artículo científico publicado en 1995

Chromosome translocation based on illegitimate recombination in human tumors

artículo científico publicado en 1998

Chronic exposure to sublethal doses of radiation mimetic Zeocin selects for clones deficient in homologous recombination.

artículo científico publicado en 2006

Control of alternative end joining by the chromatin remodeler p400 ATPase.

artículo científico publicado en 2015

CtIP fusion to Cas9 enhances transgene integration by homology-dependent repair

artículo científico publicado en 2018

DNA double-strand break repair signalling: the case of RAD51 post-translational regulation.

artículo científico publicado en 2002

Directional recombination is initiated at a double strand break in human nuclear extracts ⬇️

artículo científico publicado el 11 de febrero de 1992

Down-regulation of BRCA1 expression by miR-146a and miR-146b-5p in triple negative sporadic breast cancers.

artículo científico publicado en 2011

Genetic interactions between RAD51 and its paralogues for centrosome fragmentation and ploidy control, independently of the sensitivity to genotoxic stresses

artículo científico publicado en 2005

Genomic rearrangements induced by unscheduled DNA double strand breaks in somatic mammalian cells.

artículo científico publicado en 2017

Homologous pairing between single-stranded DNA immobilized on a nitrocellulose membrane and duplex DNA is specific for RecA activity in bacterial crude extract

artículo científico publicado en 1993

Homologous recombination induced by replication inhibition, is stimulated by expression of mutant p53.

artículo científico publicado en 2002

Homologous recombination is involved in the repair response of mammalian cells to low doses of tritium

artículo científico publicado en 2008

Impact of the KU80 pathway on NHEJ-induced genome rearrangements in mammalian cells.

artículo científico publicado en 2004

Improving gene replacement by intracellular formation of linear homologous DNA.

artículo científico publicado en 2005

Inactivation of the RAD51 recombination pathway stimulates UV-induced mutagenesis in mammalian cells

scientific article published on 01 June 2002

Increase of spontaneous intrachromosomal homologous recombination in mammalian cells expressing a mutant p53 protein

artículo científico publicado en 1997

Involvement of DNA polymerase mu in the repair of a specific subset of DNA double-strand breaks in mammalian cells.

artículo científico publicado en 2007

Is homologous recombination really an error-free process?

artículo científico publicado en 2014

Is non-homologous end-joining really an inherently error-prone process?

artículo científico

Molecular analysis of homologous recombination catalysed by human nuclear extract: fidelity and DNase protection

artículo científico publicado en 1989

Mutant p53 proteins stimulate spontaneous and radiation-induced intrachromosomal homologous recombination independently of the alteration of the transactivation activity and of the G1 checkpoint.

artículo científico publicado en 1999

Overexpression of mammalian Rad51 does not stimulate tumorigenesis while a dominant-negative Rad51 affects centrosome fragmentation, ploidy and stimulates tumorigenesis, in p53-defective CHO cells.

artículo científico publicado en 2003

Oxidative stress induces an ATM-independent senescence pathway through p38 MAPK-mediated lamin B1 accumulation ⬇️

artículo científico publicado el 13 de enero de 2012

PARP2 controls double-strand break repair pathway choice by limiting 53BP1 accumulation at DNA damage sites and promoting end-resection

artículo científico publicado en 2017

PARP3 affects the relative contribution of homologous recombination and nonhomologous end-joining pathways.

artículo científico publicado en 2014

Phospho-Ku70 induced by DNA damage interacts with RNA Pol II and promotes the formation of phospho-53BP1 foci to ensure optimal cNHEJ

artículo científico publicado en 2021

Physical interactions between DNA and sepiolite nanofibers, and potential application for DNA transfer into mammalian cells

artículo científico publicado en 2016

Polo-like kinase 3 regulates CtIP during DNA double-strand break repair in G1.

artículo científico publicado en 2014

Replication Stress, DNA Damage, Inflammatory Cytokines and Innate Immune Response

scientific article published on 09 April 2020

Replication stress in Mammalian cells and its consequences for mitosis

artículo científico publicado en 2015

RhoB promotes γH2AX dephosphorylation and DNA double-strand break repair

artículo científico publicado en 2014

Role of RAD51 in sister-chromatid exchanges in mammalian cells.

artículo científico publicado en 2001

Role of the double-strand break repair pathway in the maintenance of genomic stability.

artículo científico publicado en 2014

S-phase progression stimulates both the mutagenic KU-independent pathway and mutagenic processing of KU-dependent intermediates, for nonhomologous end joining

artículo científico publicado en 2007

Sepiolite as a New Nanocarrier for DNA Transfer into Mammalian Cells: Proof of Concept, Issues and Perspectives

artículo científico publicado en 2017

Signaling from Mus81-Eme2-Dependent DNA Damage Elicited by Chk1 Deficiency Modulates Replication Fork Speed and Origin Usage.

artículo científico publicado en 2016

Slow Replication Fork Velocity of Homologous Recombination-Defective Cells Results from Endogenous Oxidative Stress

artículo científico publicado en 2016

Spontaneous slow replication fork progression elicits mitosis alterations in homologous recombination-deficient mammalian cells.

artículo científico publicado en 2013

Structural effect of donor DNA on the initiation of recombination for double strand break repair in human nuclear extracts ⬇️

artículo científico publicado el 11 de octubre de 1992

Targeted gene correction with 5' acridine-oligonucleotide conjugates.

artículo científico

Terminal deoxynucleotidyl transferase requires KU80 and XRCC4 to promote N-addition at non-V(D)J chromosomal breaks in non-lymphoid cells

artículo científico publicado en 2012

The Cohesin Complex Prevents the End Joining of Distant DNA Double-Strand Ends.

artículo científico publicado en 2015

The DNA polymerase lambda is required for the repair of non-compatible DNA double strand breaks by NHEJ in mammalian cells

artículo científico publicado en 2006

The causes of replication stress and their consequences on genome stability and cell fate.

artículo científico publicado en 2014

The cohesin complex prevents the end-joining of distant DNA double-strand ends in S phase: Consequences on genome stability maintenance

artículo científico publicado en 2016

The helicase FBH1 is tightly regulated by PCNA via CRL4(Cdt2)-mediated proteolysis in human cells

artículo científico publicado en 2013

The nucleoporin 153, a novel factor in double-strand break repair and DNA damage response.

artículo científico publicado en 2012

The secret life of Bcl-2: Apoptosis-independent inhibition of DNA repair by Bcl-2 family members ⬇️

artículo científico publicado el 4 de junio de 2012

Yeast cells reveal the misfolding and the cellular mislocalization of the human BRCA1 protein.

artículo científico publicado en 2016

[Direct role of p53 on homologous recombination]

artículo científico publicado en 2005

[Double strand break repair, one mechanism can hide another: alternative non-homologous end joining]

artículo científico publicado en 2011

p53's double life: transactivation-independent repression of homologous recombination.

artículo científico publicado en 2004

Lista de obras de Bernard Lopez

53BP1 Protects against CtIP-Dependent Capture of Ectopic Chromosomal Sequences at the Junction of Distant Double-Strand Breaks

A homologous recombination defect affects replication-fork progression in mammalian cells.

A nonsense mutation in the DNA repair factor Hebo causes mild bone marrow failure and microcephaly.

A role for BLM in double-strand break repair pathway choice: prevention of CtIP/Mre11-mediated alternative nonhomologous end-joining.

A threshold of endogenous stress is required to engage cellular response to protect against mutagenesis.

AKT1 represses gene conversion induced by different genotoxic stresses and induces supernumerary centrosomes and aneuploidy in hamster ovary cells.

AKT1/BRCA1 in the control of homologous recombination and genetic stability: the missing link between hereditary and sporadic breast cancers ⬇️

Alpha-thalassemia haplotypes in the Algerian population

An in vitro enzymatic assay coupled to proteomics analysis reveals a new DNA processing activity for Ewing sarcoma and TAF(II)68 proteins.

An xrcc4 defect or Wortmannin stimulates homologous recombination specifically induced by double-strand breaks in mammalian cells.

Analysis of intrachromosomal homologous recombination in mammalian cell, using tandem repeat sequences.

Bax and Bid, two proapoptotic Bcl-2 family members, inhibit homologous recombination, independently of apoptosis regulation.

Bcl-2 inhibits nuclear homologous recombination by localizing BRCA1 to the endomembranes

Cellular uptake pathways of sepiolite nanofibers and DNA transfection improvement.

Characterization of homologous recombination induced by replication inhibition in mammalian cells

Characterization of mammalian RAD51 double strand break repair using non-lethal dominant-negative forms.

Characterization of two nuclear mammalian homologous DNA-pairing activities that do not require associated exonuclease activity.

Chromosome translocation based on illegitimate recombination in human tumors

Chronic exposure to sublethal doses of radiation mimetic Zeocin selects for clones deficient in homologous recombination.

Control of alternative end joining by the chromatin remodeler p400 ATPase.

CtIP fusion to Cas9 enhances transgene integration by homology-dependent repair

DNA double-strand break repair signalling: the case of RAD51 post-translational regulation.

Directional recombination is initiated at a double strand break in human nuclear extracts ⬇️

Down-regulation of BRCA1 expression by miR-146a and miR-146b-5p in triple negative sporadic breast cancers.

Genetic interactions between RAD51 and its paralogues for centrosome fragmentation and ploidy control, independently of the sensitivity to genotoxic stresses

Genomic rearrangements induced by unscheduled DNA double strand breaks in somatic mammalian cells.

Homologous pairing between single-stranded DNA immobilized on a nitrocellulose membrane and duplex DNA is specific for RecA activity in bacterial crude extract

Homologous recombination induced by replication inhibition, is stimulated by expression of mutant p53.

Homologous recombination is involved in the repair response of mammalian cells to low doses of tritium

Impact of the KU80 pathway on NHEJ-induced genome rearrangements in mammalian cells.

Improving gene replacement by intracellular formation of linear homologous DNA.

Inactivation of the RAD51 recombination pathway stimulates UV-induced mutagenesis in mammalian cells

Increase of spontaneous intrachromosomal homologous recombination in mammalian cells expressing a mutant p53 protein

Involvement of DNA polymerase mu in the repair of a specific subset of DNA double-strand breaks in mammalian cells.

Is homologous recombination really an error-free process?

Is non-homologous end-joining really an inherently error-prone process?

Molecular analysis of homologous recombination catalysed by human nuclear extract: fidelity and DNase protection

Mutant p53 proteins stimulate spontaneous and radiation-induced intrachromosomal homologous recombination independently of the alteration of the transactivation activity and of the G1 checkpoint.

Overexpression of mammalian Rad51 does not stimulate tumorigenesis while a dominant-negative Rad51 affects centrosome fragmentation, ploidy and stimulates tumorigenesis, in p53-defective CHO cells.

Oxidative stress induces an ATM-independent senescence pathway through p38 MAPK-mediated lamin B1 accumulation ⬇️

PARP2 controls double-strand break repair pathway choice by limiting 53BP1 accumulation at DNA damage sites and promoting end-resection

PARP3 affects the relative contribution of homologous recombination and nonhomologous end-joining pathways.

Phospho-Ku70 induced by DNA damage interacts with RNA Pol II and promotes the formation of phospho-53BP1 foci to ensure optimal cNHEJ

Physical interactions between DNA and sepiolite nanofibers, and potential application for DNA transfer into mammalian cells

Polo-like kinase 3 regulates CtIP during DNA double-strand break repair in G1.

Replication Stress, DNA Damage, Inflammatory Cytokines and Innate Immune Response

Replication stress in Mammalian cells and its consequences for mitosis

RhoB promotes γH2AX dephosphorylation and DNA double-strand break repair

Role of RAD51 in sister-chromatid exchanges in mammalian cells.

Role of the double-strand break repair pathway in the maintenance of genomic stability.

S-phase progression stimulates both the mutagenic KU-independent pathway and mutagenic processing of KU-dependent intermediates, for nonhomologous end joining

Sepiolite as a New Nanocarrier for DNA Transfer into Mammalian Cells: Proof of Concept, Issues and Perspectives

Signaling from Mus81-Eme2-Dependent DNA Damage Elicited by Chk1 Deficiency Modulates Replication Fork Speed and Origin Usage.

Slow Replication Fork Velocity of Homologous Recombination-Defective Cells Results from Endogenous Oxidative Stress

Spontaneous slow replication fork progression elicits mitosis alterations in homologous recombination-deficient mammalian cells.

Structural effect of donor DNA on the initiation of recombination for double strand break repair in human nuclear extracts ⬇️

Targeted gene correction with 5' acridine-oligonucleotide conjugates.

Terminal deoxynucleotidyl transferase requires KU80 and XRCC4 to promote N-addition at non-V(D)J chromosomal breaks in non-lymphoid cells

The Cohesin Complex Prevents the End Joining of Distant DNA Double-Strand Ends.

The DNA polymerase lambda is required for the repair of non-compatible DNA double strand breaks by NHEJ in mammalian cells

The causes of replication stress and their consequences on genome stability and cell fate.

The cohesin complex prevents the end-joining of distant DNA double-strand ends in S phase: Consequences on genome stability maintenance

The helicase FBH1 is tightly regulated by PCNA via CRL4(Cdt2)-mediated proteolysis in human cells

The nucleoporin 153, a novel factor in double-strand break repair and DNA damage response.

The secret life of Bcl-2: Apoptosis-independent inhibition of DNA repair by Bcl-2 family members ⬇️

Yeast cells reveal the misfolding and the cellular mislocalization of the human BRCA1 protein.

[Direct role of p53 on homologous recombination]

[Double strand break repair, one mechanism can hide another: alternative non-homologous end joining]

p53's double life: transactivation-independent repression of homologous recombination.