Lista de obras - Pieter Van Vlierberghe - Dominio Público Uruguay

A Novel t(8;14)(q24;q11) Rearranged Human Cell Line as a Model for Mechanistic and Drug Discovery Studies of NOTCH1-Independent Human T-Cell Leukemia

article

A Tumor Suppressor Enhancer of in T-cell development and leukemia

A comprehensive inventory of TLX1 controlled long non-coding RNAs in T-cell acute lymphoblastic leukemia through polyA+ and total RNA sequencing

scientific article published on 28 June 2018

A novel L-asparaginase with low L-glutaminase coactivity is highly efficacious against both T and B cell acute lymphoblastic leukemias in vivo

artículo científico publicado en 2018

A novel TLX1-driven T-ALL zebrafish model: comparative genomic analysis with other leukemia models

artículo científico publicado en 2020

A novel and universal method for microRNA RT-qPCR data normalization

artículo científico publicado en 2009

A quantitative proteomics approach identifies ETV6 and IKZF1 as new regulators of an ERG-driven transcriptional network.

artículo científico publicado en 2016

ABT-199 mediated inhibition of BCL-2 as a novel therapeutic strategy in T-cell acute lymphoblastic leukemia

artículo científico publicado en 2014

Activating FLT3 mutations in CD4+/CD8- pediatric T-cell acute lymphoblastic leukemias

scientific article published on 01 December 2005

Aging of preleukemic thymocytes drives CpG island hypermethylation in T-cell acute lymphoblastic leukemia

artículo científico publicado en 2020

CD200/BTLA deletions in pediatric precursor B-cell acute lymphoblastic leukemia treated according to the EORTC-CLG 58951 protocol

artículo científico publicado en 2015

Characterization of a set of tumor suppressor microRNAs in T cell acute lymphoblastic leukemia

artículo científico publicado en 2014

Chemotherapy at the wheel of ALL relapse

artículo científico publicado en 2020

CircRNAs Dysregulated in Juvenile Myelomonocytic Leukemia: CircMCTP1 Stands Out

artículo científico publicado en 2020

Comparison of miRNA profiles of microdissected Hodgkin/Reed-Sternberg cells and Hodgkin cell lines versus CD77+ B-cells reveals a distinct subset of differentially expressed miRNAs

artículo científico publicado en 2009

Comprehensive miRNA expression profiling in human T-cell acute lymphoblastic leukemia by small RNA-sequencing

artículo científico publicado en 2017

Contrasting roles of histone 3 lysine 27 demethylases in acute lymphoblastic leukaemia

artículo científico publicado en 2014

Controlling pre-leukemic thymocyte self-renewal

artículo científico publicado en 2014

Corrigendum: Xenopus tropicalis: Joining the Armada in the Fight Against Blood Cancer

scholarly article published in Frontiers in Physiology

Cross-talk between GLI transcription factors and FOXC1 promotes T-cell acute lymphoblastic leukemia dissemination

scientific article published on 30 July 2020

Deletion 6q Drives T-cell Leukemia Progression by Ribosome Modulation

scientific article published on 28 September 2018

Design of a Comprehensive Fluorescence in Situ Hybridization Assay for Genetic Classification of T-Cell Acute Lymphoblastic Leukemia

scientific article published on 04 March 2020

Digital Multiplex Ligation-Dependent Probe Amplification for Detection of Key Copy Number Alterations in T- and B-Cell Lymphoblastic Leukemia.

artículo científico publicado en 2017

Distinct Notch1 and BCL11B requirements mediate human γδ/αβ T cell development

scientific article published on 07 April 2020

Distinct and temporary-restricted epigenetic mechanisms regulate human αβ and γδ T cell development

artículo científico publicado en 2020

Duplication of the MYB oncogene in T cell acute lymphoblastic leukemia

artículo científico publicado en 2007

EMT transcription factors in cancer development re-evaluated: Beyond EMT and MET.

artículo científico publicado en 2017

ETV6 mutations in early immature human T cell leukemias

artículo científico publicado en 2011

EVI1-mediated down regulation of MIR449A is essential for the survival of EVI1 positive leukaemic cells

artículo científico publicado en 2011

Epigenetics in T-cell acute lymphoblastic leukemia

artículo científico publicado en 2015

Expressed repetitive elements are broadly applicable reference targets for normalization of reverse transcription-qPCR data in mice.

artículo científico publicado en 2018

Fanconi-BRCA pathway mutations in childhood T-cell acute lymphoblastic leukemia

artículo científico publicado en 2019

GATA3 induces human T-cell commitment by restraining Notch activity and repressing NK-cell fate

artículo científico publicado en 2016

Genetic characterization and therapeutic targeting of MYC-rearranged T cell acute lymphoblastic leukaemia

scientific article published on 25 June 2018

Genetic inactivation of the polycomb repressive complex 2 in T cell acute lymphoblastic leukemia

artículo científico publicado en 2012

HES1 and HES4 have non-redundant roles downstream of Notch during early human T cell development

scientific article published on 09 January 2020

Identification of two critically deleted regions within chromosome segment 7q35-q36 in EVI1 deregulated myeloid leukemia cell lines

artículo científico publicado en 2010

Integrated scRNA-Seq Identifies Human Postnatal Thymus Seeding Progenitors and Regulatory Dynamics of Differentiating Immature Thymocytes

scientific article published on 13 April 2020

LEDGF/p75 is dispensable for hematopoiesis but essential for MLL-rearranged leukemogenesis

artículo científico publicado en 2017

LIN28B is over-expressed in specific subtypes of pediatric leukemia and regulates lncRNA H19.

artículo científico publicado en 2016

LIN28B overexpression defines a novel fetal-like subgroup of juvenile myelomonocytic leukemia.

artículo científico publicado en 2015

Large-scale circular RNA deregulation in T-ALL: unlocking unique ectopic expression of molecular subtypes

artículo científico publicado en 2020

Late recurrence of childhood T-cell acute lymphoblastic leukemia frequently represents a second leukemia rather than a relapse: first evidence for genetic predisposition.

artículo científico publicado en 2011

Leukemia-associated NF1 inactivation in patients with pediatric T-ALL and AML lacking evidence for neurofibromatosis

artículo científico publicado en 2008

Long non-coding RNAs in leukemia: biology and clinical impact

artículo científico publicado en 2017

MDACT: A New Principle of Adjunctive Cancer Treatment Using Combinations of Multiple Repurposed Drugs, with an Example Regimen

artículo científico publicado en 2022

Malignant progression of donor-engrafted clonal hematopoiesis in sibling recipients after stem cell transplantation

artículo científico publicado en 2020

MicroRNA-128-3p is a novel oncomiR targeting PHF6 in T-cell acute lymphoblastic leukemia

artículo científico publicado en 2014

Molecular basis and clinical significance of genetic aberrations in B-cell precursor acute lymphoblastic leukemia

artículo científico

Molecular-genetic insights in paediatric T-cell acute lymphoblastic leukaemia

artículo científico publicado en 2008

Mutant JAK3 phosphoproteomic profiling predicts synergism between JAK3 inhibitors and MEK/BCL2 inhibitors for the treatment of T-cell acute lymphoblastic leukemia.

artículo científico

Novel biological insights in T-cell acute lymphoblastic leukemia

artículo científico

Novel oncogenic noncoding mutations in T-ALL.

artículo científico publicado en 2017

Novel strategy for rapid functional in vivo validation of oncogenic drivers in haematological malignancies

scientific article published on 22 July 2019

Oncogenic ZEB2 activation drives sensitivity toward KDM1A inhibition in T-cell acute lymphoblastic leukemia

artículo científico publicado en 2017

Overcoming Steroid Resistance in T Cell Acute Lymphoblastic Leukemia.

artículo científico publicado en 2016

PHF6 Expression Levels Impact Human Hematopoietic Stem Cell Differentiation

artículo científico publicado en 2020

PHF6 mutations in T-cell acute lymphoblastic leukemia

artículo científico publicado en 2010

PRC2 loss induces chemoresistance by repressing apoptosis in T cell acute lymphoblastic leukemia

article

PRL3 enhances T-cell acute lymphoblastic leukemia growth through suppressing T-cell signaling pathways and apoptosis

artículo científico publicado en 2020

PTEN abnormalities predict poor outcome in children with T-cell acute lymphoblastic leukemia treated according to ALL IC-BFM protocols

artículo científico publicado en 2019

ParMap, an algorithm for the identification of small genomic insertions and deletions in nextgen sequencing data

artículo científico publicado en 2010

Phf6 Loss Enhances HSC Self-Renewal Driving Tumor Initiation and Leukemia Stem Cell Activity in T-ALL

scientific article published on 19 December 2018

Posttranslational regulation of the exon skipping machinery controls aberrant splicing in leukemia

artículo científico publicado en 2020

Pre-clinical evaluation of second generation PIM inhibitors for the treatment of T-cell acute lymphoblastic leukemia and lymphoma

artículo científico publicado en 2018

Prognostic relevance of integrated genetic profiling in acute myeloid leukemia

artículo científico publicado en 2012

Prognostic relevance of integrated genetic profiling in adult T-cell acute lymphoblastic leukemia

artículo científico publicado en 2013

Results of successive EORTC-CLG 58 881 and 58 951 trials in paediatric T-cell acute lymphoblastic leukaemia (ALL)

scientific article published on 24 May 2019

SHQ1 regulation of RNA splicing is required for T-lymphoblastic leukemia cell survival

scientific article published in Nature Communications

Single cell profiling of immature human postnatal thymocytes resolves the complexity of intra-thymic lineage differentiation and thymus seeding precursors ⬇️

artículo científico publicado en 2020

T-ALL and thymocytes: a message of noncoding RNAs

artículo científico publicado en 2017

T-cell acute lymphoblastic leukemias express a unique truncated FAT1 isoform that cooperates with NOTCH1 in leukemia development

artículo científico publicado en 2018

Targeting cytokine and therapy induced PIM1 activation in T-cell acute lymphoblastic leukemia and lymphoma

scientific article published on 13 February 2020

Targeting steroid resistance in T-cell acute lymphoblastic leukemia

artículo científico publicado en 2019

The EMT modulator SNAI1 contributes to AML pathogenesis via its interaction with LSD1

scientific article published on 05 May 2020

The EMT transcription factor ZEB2 promotes proliferation of primary and metastatic melanoma while suppressing an invasive, mesenchymal-like phenotype

artículo científico publicado en 2020

The H3K27me3 demethylase UTX in normal development and disease

artículo científico publicado en 2014

The H3K27me3 demethylase UTX is a gender-specific tumor suppressor in T-cell acute lymphoblastic leukemia

artículo científico publicado en 2014

The Notch driven long non-coding RNA repertoire in T-cell acute lymphoblastic leukemia

artículo científico publicado en 2014

The TLX1 oncogene drives aneuploidy in T cell transformation

artículo científico publicado en 2010

The cryptic chromosomal deletion del(11)(p12p13) as a new activation mechanism of LMO2 in pediatric T-cell acute lymphoblastic leukemia

artículo científico publicado en 2006

The epigenetic landscape of T-cell acute lymphoblastic leukemia

artículo científico

The long non-coding RNA landscape in juvenile myelomonocytic leukemia

scientific article published on 01 June 2018

The molecular basis of T cell acute lymphoblastic leukemia

artículo científico publicado en 2012

The recurrent SET-NUP214 fusion as a new HOXA activation mechanism in pediatric T-cell acute lymphoblastic leukemia

artículo científico publicado en 2008

The transcription factor ETS1 is an important regulator of human NK cell development and terminal differentiation

artículo científico publicado en 2020

Three-dimensional chromatin landscapes in T cell acute lymphoblastic leukemia

artículo científico publicado en 2020

USP7 Cooperates with NOTCH1 to Drive the Oncogenic Transcriptional Program in T-Cell Leukemia

artículo científico publicado en 2018

Unique long non-coding RNA expression signature in ETV6/RUNX1-driven B-cell precursor acute lymphoblastic leukemia

artículo científico publicado en 2016

ZEB Proteins in Leukemia: Friends, Foes, or Friendly Foes?

artículo científico publicado en 2018

ZEB2 and LMO2 drive immature T-cell lymphoblastic leukemia via distinct oncogenic mechanisms

scientific article published on 24 January 2019

ZEB2 drives immature T-cell lymphoblastic leukaemia development via enhanced tumour-initiating potential and IL-7 receptor signalling.

artículo científico publicado en 2015

ZEB2 in T-cells and T-ALL

artículo científico publicado en 2019

hsa-miR-20b-5p and hsa-miR-363-3p Affect Expression of PTEN and BIM Tumor Suppressor Genes and Modulate Survival of T-ALL Cells In Vitro

scientific article published on 05 May 2020

Lista de obras de Pieter Van Vlierberghe

A Novel t(8;14)(q24;q11) Rearranged Human Cell Line as a Model for Mechanistic and Drug Discovery Studies of NOTCH1-Independent Human T-Cell Leukemia

A Tumor Suppressor Enhancer of in T-cell development and leukemia

A comprehensive inventory of TLX1 controlled long non-coding RNAs in T-cell acute lymphoblastic leukemia through polyA+ and total RNA sequencing

A novel L-asparaginase with low L-glutaminase coactivity is highly efficacious against both T and B cell acute lymphoblastic leukemias in vivo

A novel TLX1-driven T-ALL zebrafish model: comparative genomic analysis with other leukemia models

A novel and universal method for microRNA RT-qPCR data normalization

A quantitative proteomics approach identifies ETV6 and IKZF1 as new regulators of an ERG-driven transcriptional network.

ABT-199 mediated inhibition of BCL-2 as a novel therapeutic strategy in T-cell acute lymphoblastic leukemia

Activating FLT3 mutations in CD4+/CD8- pediatric T-cell acute lymphoblastic leukemias

Aging of preleukemic thymocytes drives CpG island hypermethylation in T-cell acute lymphoblastic leukemia

CD200/BTLA deletions in pediatric precursor B-cell acute lymphoblastic leukemia treated according to the EORTC-CLG 58951 protocol

Characterization of a set of tumor suppressor microRNAs in T cell acute lymphoblastic leukemia

Chemotherapy at the wheel of ALL relapse

CircRNAs Dysregulated in Juvenile Myelomonocytic Leukemia: CircMCTP1 Stands Out

Comparison of miRNA profiles of microdissected Hodgkin/Reed-Sternberg cells and Hodgkin cell lines versus CD77+ B-cells reveals a distinct subset of differentially expressed miRNAs

Comprehensive miRNA expression profiling in human T-cell acute lymphoblastic leukemia by small RNA-sequencing

Contrasting roles of histone 3 lysine 27 demethylases in acute lymphoblastic leukaemia

Controlling pre-leukemic thymocyte self-renewal

Corrigendum: Xenopus tropicalis: Joining the Armada in the Fight Against Blood Cancer

Cross-talk between GLI transcription factors and FOXC1 promotes T-cell acute lymphoblastic leukemia dissemination

Deletion 6q Drives T-cell Leukemia Progression by Ribosome Modulation

Design of a Comprehensive Fluorescence in Situ Hybridization Assay for Genetic Classification of T-Cell Acute Lymphoblastic Leukemia

Digital Multiplex Ligation-Dependent Probe Amplification for Detection of Key Copy Number Alterations in T- and B-Cell Lymphoblastic Leukemia.

Distinct Notch1 and BCL11B requirements mediate human γδ/αβ T cell development

Distinct and temporary-restricted epigenetic mechanisms regulate human αβ and γδ T cell development

Duplication of the MYB oncogene in T cell acute lymphoblastic leukemia

EMT transcription factors in cancer development re-evaluated: Beyond EMT and MET.

ETV6 mutations in early immature human T cell leukemias

EVI1-mediated down regulation of MIR449A is essential for the survival of EVI1 positive leukaemic cells

Epigenetics in T-cell acute lymphoblastic leukemia

Expressed repetitive elements are broadly applicable reference targets for normalization of reverse transcription-qPCR data in mice.

Fanconi-BRCA pathway mutations in childhood T-cell acute lymphoblastic leukemia

GATA3 induces human T-cell commitment by restraining Notch activity and repressing NK-cell fate

Genetic characterization and therapeutic targeting of MYC-rearranged T cell acute lymphoblastic leukaemia

Genetic inactivation of the polycomb repressive complex 2 in T cell acute lymphoblastic leukemia

HES1 and HES4 have non-redundant roles downstream of Notch during early human T cell development

Identification of two critically deleted regions within chromosome segment 7q35-q36 in EVI1 deregulated myeloid leukemia cell lines

Integrated scRNA-Seq Identifies Human Postnatal Thymus Seeding Progenitors and Regulatory Dynamics of Differentiating Immature Thymocytes

LEDGF/p75 is dispensable for hematopoiesis but essential for MLL-rearranged leukemogenesis

LIN28B is over-expressed in specific subtypes of pediatric leukemia and regulates lncRNA H19.

LIN28B overexpression defines a novel fetal-like subgroup of juvenile myelomonocytic leukemia.

Large-scale circular RNA deregulation in T-ALL: unlocking unique ectopic expression of molecular subtypes

Late recurrence of childhood T-cell acute lymphoblastic leukemia frequently represents a second leukemia rather than a relapse: first evidence for genetic predisposition.

Leukemia-associated NF1 inactivation in patients with pediatric T-ALL and AML lacking evidence for neurofibromatosis

Long non-coding RNAs in leukemia: biology and clinical impact

MDACT: A New Principle of Adjunctive Cancer Treatment Using Combinations of Multiple Repurposed Drugs, with an Example Regimen

Malignant progression of donor-engrafted clonal hematopoiesis in sibling recipients after stem cell transplantation

MicroRNA-128-3p is a novel oncomiR targeting PHF6 in T-cell acute lymphoblastic leukemia

Molecular basis and clinical significance of genetic aberrations in B-cell precursor acute lymphoblastic leukemia

Molecular-genetic insights in paediatric T-cell acute lymphoblastic leukaemia

Mutant JAK3 phosphoproteomic profiling predicts synergism between JAK3 inhibitors and MEK/BCL2 inhibitors for the treatment of T-cell acute lymphoblastic leukemia.

Novel biological insights in T-cell acute lymphoblastic leukemia

Novel oncogenic noncoding mutations in T-ALL.

Novel strategy for rapid functional in vivo validation of oncogenic drivers in haematological malignancies

Oncogenic ZEB2 activation drives sensitivity toward KDM1A inhibition in T-cell acute lymphoblastic leukemia

Overcoming Steroid Resistance in T Cell Acute Lymphoblastic Leukemia.

PHF6 Expression Levels Impact Human Hematopoietic Stem Cell Differentiation

PHF6 mutations in T-cell acute lymphoblastic leukemia

PRC2 loss induces chemoresistance by repressing apoptosis in T cell acute lymphoblastic leukemia

PRL3 enhances T-cell acute lymphoblastic leukemia growth through suppressing T-cell signaling pathways and apoptosis

PTEN abnormalities predict poor outcome in children with T-cell acute lymphoblastic leukemia treated according to ALL IC-BFM protocols

ParMap, an algorithm for the identification of small genomic insertions and deletions in nextgen sequencing data

Phf6 Loss Enhances HSC Self-Renewal Driving Tumor Initiation and Leukemia Stem Cell Activity in T-ALL

Posttranslational regulation of the exon skipping machinery controls aberrant splicing in leukemia

Pre-clinical evaluation of second generation PIM inhibitors for the treatment of T-cell acute lymphoblastic leukemia and lymphoma

Prognostic relevance of integrated genetic profiling in acute myeloid leukemia

Prognostic relevance of integrated genetic profiling in adult T-cell acute lymphoblastic leukemia

Results of successive EORTC-CLG 58 881 and 58 951 trials in paediatric T-cell acute lymphoblastic leukaemia (ALL)

SHQ1 regulation of RNA splicing is required for T-lymphoblastic leukemia cell survival

Single cell profiling of immature human postnatal thymocytes resolves the complexity of intra-thymic lineage differentiation and thymus seeding precursors ⬇️

T-ALL and thymocytes: a message of noncoding RNAs

T-cell acute lymphoblastic leukemias express a unique truncated FAT1 isoform that cooperates with NOTCH1 in leukemia development

Targeting cytokine and therapy induced PIM1 activation in T-cell acute lymphoblastic leukemia and lymphoma

Targeting steroid resistance in T-cell acute lymphoblastic leukemia

The EMT modulator SNAI1 contributes to AML pathogenesis via its interaction with LSD1

The EMT transcription factor ZEB2 promotes proliferation of primary and metastatic melanoma while suppressing an invasive, mesenchymal-like phenotype

The H3K27me3 demethylase UTX in normal development and disease

The H3K27me3 demethylase UTX is a gender-specific tumor suppressor in T-cell acute lymphoblastic leukemia

The Notch driven long non-coding RNA repertoire in T-cell acute lymphoblastic leukemia