Lista de obras - Alexander Schramm - Dominio Público Uruguay

5-Year Outcome Following Randomized Treatment of All-Comers With Zotarolimus-Eluting Resolute Integrity and Everolimus-Eluting PROMUS Element Coronary Stents: Final Report of the DUTCH PEERS (TWENTE II) Trial.

artículo científico publicado en 2018

A Quantitative Approach to Orbital Decompression in Graves' Disease Using Computer-Assisted Surgery: A Compilation of Different Techniques and Introduction of the “Temporal Cage” ⬇️

artículo científico publicado el 16 de julio de 2011

A mechanistic classification of clinical phenotypes in neuroblastoma

artículo científico publicado en 2018

A prospective multicenter study to compare the precision of posttraumatic internal orbital reconstruction with standard preformed and individualized orbital implants

artículo científico publicado en 2016

Accurate outcome prediction in neuroblastoma across independent data sets using a multigene signature

artículo científico publicado en 2010

Accurate prediction of neuroblastoma outcome based on miRNA expression profiles

artículo científico publicado en 2010

Advances and innovations in computer-assisted head and neck oncologic surgery

artículo científico publicado en 2012

Amplification of N-Myc is associated with a T-cell-poor microenvironment in metastatic neuroblastoma restraining interferon pathway activity and chemokine expression

artículo científico publicado en 2017

ArrayCGH-based classification of neuroblastoma into genomic subgroups

artículo científico publicado en 2007

Bifurcation treatment with novel, highly flexible drug-eluting coronary stents in all-comers: 2-year outcome in patients of the DUTCH PEERS trial

artículo científico publicado en 2015

CADM1 is a strong neuroblastoma candidate gene that maps within a 3.72 Mb critical region of loss on 11q23

artículo científico publicado en 2008

Cancer evolution, mutations, and clonal selection in relapse neuroblastoma

artículo científico publicado en 2018

Chromosomal and microRNA expression patterns reveal biologically distinct subgroups of 11q- neuroblastoma

artículo científico publicado en 2010

Deep sequencing reveals differential expression of microRNAs in favorable versus unfavorable neuroblastoma

artículo científico publicado en 2010

Design of a modular protein-based MRI contrast agent for targeted application.

artículo científico publicado en 2013

Design of a multi-signature ensemble classifier predicting neuroblastoma patients' outcome

artículo científico publicado en 2012

Dickkopf-3 is regulated by the MYCN-induced miR-17-92 cluster in neuroblastoma

scientific journal article

Discovery of a new bioactive molecule for neuroblastoma

artículo científico publicado en 2013

Fractalkine (CX3CL1)- and interleukin-2-enriched neuroblastoma microenvironment induces eradication of metastases mediated by T cells and natural killer cells.

artículo científico publicado en 2007

Frequent codeletion of p16/MTS1 and p15/MTS2 and genetic alterations in p16/MTS1 in pancreatic tumors

artículo científico publicado en 1996

Functional screening identifies aryl hydrocarbon receptor as suppressor of lung cancer metastasis

artículo científico publicado en 2020

Gains and overexpression identify DEK and E2F3 as targets of chromosome 6p gains in retinoblastoma.

artículo científico publicado en 2005

Galectin-1 is a major effector of TrkB-mediated neuroblastoma aggressiveness.

artículo científico publicado en 2009

High ALK receptor tyrosine kinase expression supersedes ALK mutation as a determining factor of an unfavorable phenotype in primary neuroblastoma

artículo científico publicado en 2011

High resolution tiling-path BAC array deletion mapping suggests commonly involved 3p21-p22 tumor suppressor genes in neuroblastoma and more frequent tumors

artículo científico publicado en 2007

Homozygous loss of the MTS1/p16 and MTS2/p15 genes in lymphoma and lymphoblastic leukaemia cell lines

artículo científico publicado en 1995

Human fetal neuroblast and neuroblastoma transcriptome analysis confirms neuroblast origin and highlights neuroblastoma candidate genes

artículo científico publicado en 2006

IL-2−driven Regulation of NK Cell Receptors With Regard to the Distribution of CD16+ and CD16− Subpopulations and In Vivo Influence After Haploidentical NK Cell Infusion

scientific article published on 01 February 2010

Identification and Tumour-Binding Properties of a Peptide with High Affinity to the Disialoganglioside GD2.

artículo científico publicado en 2016

Identification of a novel recurrent 1q42.2-1qter deletion in high risk MYCN single copy 11q deleted neuroblastomas

artículo científico publicado en 2011

Identification of dynamic proteome changes upon ligand activation of Trk-receptors using two-dimensional fluorescence difference gel electrophoresis and mass spectrometry.

artículo científico publicado en 2005

Lysine-specific demethylase 1 is strongly expressed in poorly differentiated neuroblastoma: implications for therapy

artículo científico publicado en 2009

Lysine-specific demethylase 1 restricts hematopoietic progenitor proliferation and is essential for terminal differentiation

artículo científico publicado en 2012

MYCN and ALKF1174L are sufficient to drive neuroblastoma development from neural crest progenitor cells

artículo científico publicado en 2012

MYCN regulates oncogenic MicroRNAs in neuroblastoma

artículo científico publicado en 2008

MYCN/c-MYC-induced microRNAs repress coding gene networks associated with poor outcome in MYCN/c-MYC-activated tumors.

artículo científico publicado en 2009

Meta-mining of neuroblastoma and neuroblast gene expression profiles reveals candidate therapeutic compounds

artículo científico publicado en 2009

MiR-137 functions as a tumor suppressor in neuroblastoma by downregulating KDM1A.

artículo científico publicado en 2013

MiR-34a deficiency accelerates medulloblastoma formation in vivo

artículo científico publicado en 2014

MicroRNAs in the pathogenesis of neuroblastoma.

artículo científico publicado en 2008

Modulation of neuroblastoma disease pathogenesis by an extensive network of epigenetically regulated microRNAs

artículo científico publicado en 2012

Mutational dynamics between primary and relapse neuroblastomas.

artículo científico publicado en 2015

N-Myc-induced metabolic rewiring creates novel therapeutic vulnerabilities in neuroblastoma

scientific article published on 28 April 2020

Neuroblastoma tumorigenesis is regulated through the Nm23-H1/h-Prune C-terminal interaction

artículo científico publicado en 2013

Pharmacological activation of the p53 pathway by nutlin-3 exerts anti-tumoral effects in medulloblastomas

artículo científico publicado en 2012

Polo-like kinase 1 is a therapeutic target in high-risk neuroblastoma

artículo científico publicado en 2010

Prediction of clinical outcome and biological characterization of neuroblastoma by expression profiling

artículo científico publicado en 2005

Reanalysis of neuroblastoma expression profiling data using improved methodology and extended follow-up increases validity of outcome prediction

artículo científico publicado en 2009

Smac mimetic LBW242 sensitizes XIAP-overexpressing neuroblastoma cells for TNF-α-independent apoptosis

artículo científico publicado en 2012

Small-vessel treatment with contemporary newer-generation drug-eluting coronary stents in all-comers: Insights from 2-year DUTCH PEERS (TWENTE II) randomized trial

artículo científico publicado en 2016

Streamlining Quantitative Analysis of Long RNA Sequencing Reads

scientific article published on 01 October 2020

Synthetic lethality between Rb, p53 and Dicer or miR-17-92 in retinal progenitors suppresses retinoblastoma formation

artículo científico publicado en 2012

TCT-19 Two-Year Clinical Outcome and Chest Pain in 1,811 All-Comer Patients, Treated for Bifurcated Versus Non-Bifurcated Lesions With Highly Deliverable Drug-Eluting Coronary Stents

TCT-570 3-Year Clinical Outcome of the DUTCH PEERS (TWENTE II) Randomized Trial: Cobalt-Chromium Zotarolimus-Eluting Resolute Integrity Versus Platinum-Chromium Everolimus-Eluting Promus Element Stents in All-Comer Patients

scholarly article by Clemens von Birgelen et al published October 2015 in Journal of the American College of Cardiology

Taraxacum officinale extract shows antitumor effects on pediatric cancer cells and enhance mistletoe therapy

artículo científico publicado en 2018

Targeted Therapy for Neuroblastoma: ALK Inhibitors.

artículo científico publicado en 2013

Targeted expression of mutated ALK induces neuroblastoma in transgenic mice.

artículo científico publicado en 2012

Targeting the phosphoinositide 3-kinase isoform p110delta impairs growth and survival in neuroblastoma cells.

artículo científico publicado en 2008

The BCL2-938 C > A promoter polymorphism is associated with risk group classification in children with acute lymphoblastic leukemia.

artículo científico publicado en 2013

The metallophosphodiesterase Mpped2 impairs tumorigenesis in neuroblastoma.

artículo científico publicado en 2012

The miR-17-92 microRNA cluster regulates multiple components of the TGF-β pathway in neuroblastoma

artículo científico publicado en 2010

Third-generation zotarolimus-eluting and everolimus-eluting stents in all-comer patients requiring a percutaneous coronary intervention (DUTCH PEERS): a randomised, single-blind, multicentre, non-inferiority trial

scientific article published on 31 October 2013

Translating expression profiling into a clinically feasible test to predict neuroblastoma outcome

artículo científico publicado en 2007

TrkB-Target Galectin-1 Impairs Immune Activation and Radiation Responses in Neuroblastoma: Implications for Tumour Therapy.

artículo científico publicado en 2018

Xenogeneic immunization with human tyrosine hydroxylase DNA vaccines suppresses growth of established neuroblastoma.

artículo científico publicado en 2009

Lista de obras de Alexander Schramm

5-Year Outcome Following Randomized Treatment of All-Comers With Zotarolimus-Eluting Resolute Integrity and Everolimus-Eluting PROMUS Element Coronary Stents: Final Report of the DUTCH PEERS (TWENTE II) Trial.

A Quantitative Approach to Orbital Decompression in Graves' Disease Using Computer-Assisted Surgery: A Compilation of Different Techniques and Introduction of the “Temporal Cage” ⬇️

A mechanistic classification of clinical phenotypes in neuroblastoma

A prospective multicenter study to compare the precision of posttraumatic internal orbital reconstruction with standard preformed and individualized orbital implants

Accurate outcome prediction in neuroblastoma across independent data sets using a multigene signature

Accurate prediction of neuroblastoma outcome based on miRNA expression profiles

Advances and innovations in computer-assisted head and neck oncologic surgery

Amplification of N-Myc is associated with a T-cell-poor microenvironment in metastatic neuroblastoma restraining interferon pathway activity and chemokine expression

ArrayCGH-based classification of neuroblastoma into genomic subgroups

Bifurcation treatment with novel, highly flexible drug-eluting coronary stents in all-comers: 2-year outcome in patients of the DUTCH PEERS trial

CADM1 is a strong neuroblastoma candidate gene that maps within a 3.72 Mb critical region of loss on 11q23

Cancer evolution, mutations, and clonal selection in relapse neuroblastoma

Chromosomal and microRNA expression patterns reveal biologically distinct subgroups of 11q- neuroblastoma

Deep sequencing reveals differential expression of microRNAs in favorable versus unfavorable neuroblastoma

Design of a modular protein-based MRI contrast agent for targeted application.

Design of a multi-signature ensemble classifier predicting neuroblastoma patients' outcome

Dickkopf-3 is regulated by the MYCN-induced miR-17-92 cluster in neuroblastoma

Discovery of a new bioactive molecule for neuroblastoma

Fractalkine (CX3CL1)- and interleukin-2-enriched neuroblastoma microenvironment induces eradication of metastases mediated by T cells and natural killer cells.

Frequent codeletion of p16/MTS1 and p15/MTS2 and genetic alterations in p16/MTS1 in pancreatic tumors

Functional screening identifies aryl hydrocarbon receptor as suppressor of lung cancer metastasis

Gains and overexpression identify DEK and E2F3 as targets of chromosome 6p gains in retinoblastoma.

Galectin-1 is a major effector of TrkB-mediated neuroblastoma aggressiveness.

High ALK receptor tyrosine kinase expression supersedes ALK mutation as a determining factor of an unfavorable phenotype in primary neuroblastoma

High resolution tiling-path BAC array deletion mapping suggests commonly involved 3p21-p22 tumor suppressor genes in neuroblastoma and more frequent tumors

Homozygous loss of the MTS1/p16 and MTS2/p15 genes in lymphoma and lymphoblastic leukaemia cell lines

Human fetal neuroblast and neuroblastoma transcriptome analysis confirms neuroblast origin and highlights neuroblastoma candidate genes

IL-2−driven Regulation of NK Cell Receptors With Regard to the Distribution of CD16+ and CD16− Subpopulations and In Vivo Influence After Haploidentical NK Cell Infusion

Identification and Tumour-Binding Properties of a Peptide with High Affinity to the Disialoganglioside GD2.

Identification of a novel recurrent 1q42.2-1qter deletion in high risk MYCN single copy 11q deleted neuroblastomas

Identification of dynamic proteome changes upon ligand activation of Trk-receptors using two-dimensional fluorescence difference gel electrophoresis and mass spectrometry.

Lysine-specific demethylase 1 is strongly expressed in poorly differentiated neuroblastoma: implications for therapy

Lysine-specific demethylase 1 restricts hematopoietic progenitor proliferation and is essential for terminal differentiation

MYCN and ALKF1174L are sufficient to drive neuroblastoma development from neural crest progenitor cells

MYCN regulates oncogenic MicroRNAs in neuroblastoma

MYCN/c-MYC-induced microRNAs repress coding gene networks associated with poor outcome in MYCN/c-MYC-activated tumors.

Meta-mining of neuroblastoma and neuroblast gene expression profiles reveals candidate therapeutic compounds

MiR-137 functions as a tumor suppressor in neuroblastoma by downregulating KDM1A.

MiR-34a deficiency accelerates medulloblastoma formation in vivo

MicroRNAs in the pathogenesis of neuroblastoma.

Modulation of neuroblastoma disease pathogenesis by an extensive network of epigenetically regulated microRNAs

Mutational dynamics between primary and relapse neuroblastomas.

N-Myc-induced metabolic rewiring creates novel therapeutic vulnerabilities in neuroblastoma

Neuroblastoma tumorigenesis is regulated through the Nm23-H1/h-Prune C-terminal interaction

Pharmacological activation of the p53 pathway by nutlin-3 exerts anti-tumoral effects in medulloblastomas

Polo-like kinase 1 is a therapeutic target in high-risk neuroblastoma

Prediction of clinical outcome and biological characterization of neuroblastoma by expression profiling

Reanalysis of neuroblastoma expression profiling data using improved methodology and extended follow-up increases validity of outcome prediction

Smac mimetic LBW242 sensitizes XIAP-overexpressing neuroblastoma cells for TNF-α-independent apoptosis

Small-vessel treatment with contemporary newer-generation drug-eluting coronary stents in all-comers: Insights from 2-year DUTCH PEERS (TWENTE II) randomized trial

Streamlining Quantitative Analysis of Long RNA Sequencing Reads

Synthetic lethality between Rb, p53 and Dicer or miR-17-92 in retinal progenitors suppresses retinoblastoma formation

TCT-19 Two-Year Clinical Outcome and Chest Pain in 1,811 All-Comer Patients, Treated for Bifurcated Versus Non-Bifurcated Lesions With Highly Deliverable Drug-Eluting Coronary Stents

TCT-570 3-Year Clinical Outcome of the DUTCH PEERS (TWENTE II) Randomized Trial: Cobalt-Chromium Zotarolimus-Eluting Resolute Integrity Versus Platinum-Chromium Everolimus-Eluting Promus Element Stents in All-Comer Patients

Taraxacum officinale extract shows antitumor effects on pediatric cancer cells and enhance mistletoe therapy

Targeted Therapy for Neuroblastoma: ALK Inhibitors.

Targeted expression of mutated ALK induces neuroblastoma in transgenic mice.

Targeting the phosphoinositide 3-kinase isoform p110delta impairs growth and survival in neuroblastoma cells.

The BCL2-938 C > A promoter polymorphism is associated with risk group classification in children with acute lymphoblastic leukemia.

The metallophosphodiesterase Mpped2 impairs tumorigenesis in neuroblastoma.

The miR-17-92 microRNA cluster regulates multiple components of the TGF-β pathway in neuroblastoma

Third-generation zotarolimus-eluting and everolimus-eluting stents in all-comer patients requiring a percutaneous coronary intervention (DUTCH PEERS): a randomised, single-blind, multicentre, non-inferiority trial

Translating expression profiling into a clinically feasible test to predict neuroblastoma outcome

TrkB-Target Galectin-1 Impairs Immune Activation and Radiation Responses in Neuroblastoma: Implications for Tumour Therapy.

Xenogeneic immunization with human tyrosine hydroxylase DNA vaccines suppresses growth of established neuroblastoma.