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Lista de obras de Alfredo Budillon

8-Cl-cAMP antagonizes mitogen-activated protein kinase activation and cell growth stimulation induced by epidermal growth factor.

artículo científico publicado en 1999

A Psychosocial Genomics Pilot Study in Oncology for Verifying Clinical, Inflammatory and Psychological Effects of Mind-Body Transformations-Therapy (MBT-T) in Breast Cancer Patients: Preliminary Results

artículo científico publicado en 2021

A high percentage of BRAFV600E alleles in papillary thyroid carcinoma predicts a poorer outcome

artículo científico publicado en 2012

A liver angioma colonized by colon cancer cells in a patient with two primitive localizations by colon adenocarcinoma: biologic, diagnostic and therapeutic implications

artículo científico publicado en 2005

A multidisciplinary approach is required to increase the quality of phase II/III clinical studies on biotherapies in oncology

scientific article published on 16 April 2007

A perspective on the current treatment strategies for locally advanced rectal cancer.

artículo científico

A randomized phase 3 study on the optimization of the combination of bevacizumab with FOLFOX/OXXEL in the treatment of patients with metastatic colorectal cancer-OBELICS (Optimization of BEvacizumab scheduLIng within Chemotherapy Scheme).

artículo científico publicado en 2015

A standardized flow cytometry network study for the assessment of circulating endothelial cell physiological ranges.

artículo científico publicado en 2018

Acetylation of proteins as novel target for antitumor therapy: review article.

artículo científico publicado en 2004

Acquired resistance to zoledronic acid and the parallel acquisition of an aggressive phenotype are mediated by p38-MAP kinase activation in prostate cancer cells

artículo científico publicado en 2013

Adenylate cyclase/cAMP pathway downmodulation counteracts apoptosis induced by IFN-alpha in human epidermoid cancer cells.

artículo científico publicado en 2007

An interaction network approach to study the correlation between endocrine disrupting chemicals and breast cancer.

artículo científico publicado en 2017

Annexin A1 is involved in the acquisition and maintenance of a stem cell-like/aggressive phenotype in prostate cancer cells with acquired resistance to zoledronic acid.

artículo científico publicado en 2015

Anti-VEGF treatment-resistant pancreatic cancers secrete proinflammatory factors that contribute to malignant progression by inducing an EMT cell phenotype.

artículo científico publicado en 2011

Anticancer drugs and hyperthermia enhance cytotoxicity induced by polyamine enzymatic oxidation products.

artículo científico publicado en 2007

Antitumor therapeutic strategies based on the targeting of epidermal growth factor-induced survival pathways.

artículo científico publicado en 2005

Biotin-targeted Pluronic(®) P123/F127 mixed micelles delivering niclosamide: A repositioning strategy to treat drug-resistant lung cancer cells

artículo científico publicado en 2016

Biweekly oxaliplatin, raltitrexed, 5-fluorouracil and folinic acid combination chemotherapy during preoperative radiation therapy for locally advanced rectal cancer: a phase I-II study

artículo científico publicado en 2006

C-Raf antagonizes apoptosis induced by IFN-alpha in human lung cancer cells by phosphorylation and increase of the intracellular content of elongation factor 1A.

artículo científico publicado en 2007

Cetuximab is an active treatment of metastatic and chemorefractory thymoma.

artículo científico publicado en 2007

Cisplatin, raltitrexed, levofolinic acid and 5-fluorouracil in locally advanced or metastatic squamous cell carcinoma of the head and neck: a phase I-II trial of the Southern Italy Cooperative Oncology Group (SICOG)

artículo científico publicado en 2000

Clonal evolution and resistance to EGFR blockade in the blood of colorectal cancer patients.

artículo científico publicado en 2015

Combination of Hypoglycemia and Metformin Impairs Tumor Metabolic Plasticity and Growth by Modulating the PP2A-GSK3β-MCL-1 Axis

artículo científico publicado en 2019

Concomitant occurrence of facial cutaneous and parotid gland metastases from rectal cancer after preoperative chemoradiotherapy

artículo científico publicado en 2007

Conformational analysis of the human chemokine receptor CXCR3.

artículo científico publicado en 2017

Critical role of bevacizumab scheduling in combination with pre-surgical chemo-radiotherapy in MRI-defined high-risk locally advanced rectal cancer: Results of the BRANCH trial

artículo científico publicado en 2015

Critical role of both p27KIP1 and p21CIP1/WAF1 in the antiproliferative effect of ZD1839 ('Iressa'), an epidermal growth factor receptor tyrosine kinase inhibitor, in head and neck squamous carcinoma cells

artículo científico publicado en 2003

Cyr61 downmodulation potentiates the anticancer effects of zoledronic acid in androgen-independent prostate cancer cells

artículo científico publicado en 2009

EGF activates an inducible survival response via the RAS-> Erk-1/2 pathway to counteract interferon-alpha-mediated apoptosis in epidermoid cancer cells

artículo científico publicado en 2003

EGF-R small inhibitors and anti-EGF-R antibodies: advantages and limits of a new avenue in anticancer therapy.

artículo científico publicado en 2006

Early FDG PET response assessment of preoperative radiochemotherapy in locally advanced rectal cancer: correlation with long-term outcome.

artículo científico publicado en 2012

Early evaluation using PET-FDG of the efficiency of neoadjuvant radiochemotherapy treatment in locally advanced neoplasia of the lower rectum

artículo científico publicado en 2003

Effects of α-zearalenol on the metabolome of two breast cancer cell lines by 1H-NMR approach

artículo científico publicado en 2018

Electromagnetic fields at mobile phone frequency induce apoptosis and inactivation of the multi-chaperone complex in human epidermoid cancer cells.

artículo científico publicado en 2005

Endothelial progenitor cells, defined by the simultaneous surface expression of VEGFR2 and CD133, are not detectable in healthy peripheral and cord blood

artículo científico publicado en 2015

Erratum: Clonal evolution and resistance to EGFR blockade in the blood of colorectal cancer patients

scientific article published on 01 July 2015

Evaluating the Effects of an Organic Extract from the Mediterranean Sponge Geodia cydonium on Human Breast Cancer Cell Lines.

artículo científico publicado en 2017

Evaluation of Aflatoxin M1 Effects on the Metabolomic and Cytokinomic Profiling of a Hepatoblastoma Cell Line

artículo científico publicado en 2018

Exposure to Perfluoroalkyl Substances and Sperm DNA Global Methylation in Arctic and European Populations

artículo científico publicado en 2014

Expression of COX-2, mPGE-synthase1, MDR-1 (P-gp), and Bcl-xL: a molecular pathway of H pylori-related gastric carcinogenesis.

artículo científico publicado en 2004

First international conference on new molecular targets for anticancer therapy, Naples, 22-23 June 1998.

artículo científico publicado en 1999

Frequent overexpression of multiple ErbB receptors by head and neck squamous cell carcinoma contrasts with rare antibody immunity in patients.

artículo científico publicado en 2004

HDAC inhibition potentiates immunotherapy in triple negative breast cancer

artículo científico publicado en 2017

HDAC inhibitor vorinostat enhances the antitumor effect of gefitinib in squamous cell carcinoma of head and neck by modulating ErbB receptor expression and reverting EMT.

artículo científico publicado en 2011

HSP90 identified by a proteomic approach as druggable target to reverse platinum-resistance in ovarian cancer

artículo científico publicado en 2020

Highlights of the Annual Meeting of the Italian Association for Cell Cultures (AICC): new drug delivery strategies and technological platforms for diagnosis and therapy of tumors. Part II. 6 - 7 December 2007, Naples, Italy

artículo científico publicado en 2008

Highlights of the annual meeting of the Italian Association for Cell Cultures (AICC): new drug delivery strategies and technological platforms for diagnosis and therapy of tumors (Part I) 6 - 7 December 2007, Naples, Italy

scientific article published on 01 June 2008

Histone deacetylase inhibitor ITF2357 (givinostat) reverts transformed phenotype and counteracts stemness in in vitro and in vivo models of human glioblastoma

artículo científico publicado en 2018

Histone deacetylase inhibitors: a new wave of molecular targeted anticancer agents.

artículo científico publicado en 2007

Identification and Targeting of Stem Cell-Activated Pathways in Cancer Therapy

scientific article published on 04 June 2019

Identifying a panel of genes/proteins/miRNAs modulated by arsenicals in bladder, prostate, kidney cancers

scientific article published in Scientific Reports

Implication for Cancer Stem Cells in Solid Cancer Chemo-Resistance: Promising Therapeutic Strategies Based on the Use of HDAC Inhibitors

scientific article published on 26 June 2019

Indices of methylation in sperm DNA from fertile men differ between distinct geographical regions

artículo científico publicado en 2014

Inhibiting Monocyte Recruitment to Prevent the Pro-Tumoral Activity of Tumor-Associated Macrophages in Chondrosarcoma

scientific article published on 24 April 2020

Inhibition of the self-renewal capacity of blast progenitors from acute myeloblastic leukemia patients by site-selective 8-chloroadenosine 3',5'-cyclic monophosphate

artículo científico publicado el 1 de octubre de 1992

Integrated Analysis to Study the Relationship between Tumor-Associated Selenoproteins: Focus on Prostate Cancer

scientific article published on 13 September 2020

Interferon-alpha induces apoptosis in human KB cells through a stress-dependent mitogen activated protein kinase pathway that is antagonized by epidermal growth factor

artículo científico publicado en 1999

Isoprenylation of intracellular proteins as a new target for the therapy of human neoplasms: preclinical and clinical implications.

artículo científico publicado en 2005

Large oncosomes overexpressing integrin alpha-V promote prostate cancer adhesion and invasion via AKT activation

scientific article published on 18 July 2019

Last generation of amino-bisphosphonates (N-BPs) and cancer angio-genesis: a new role for these drugs?

artículo científico publicado en 2006

Local and systemic protumorigenic effects of cancer-associated fibroblast-derived GDF15.

artículo científico publicado en 2014

Management of non-small cell lung cancer in the era of personalized medicine

artículo científico publicado en 2016

Metronomic administration of zoledronic acid and taxotere combination in castration resistant prostate cancer patients: phase I ZANTE trial

artículo científico publicado en 2010

Modulation of molecular mechanisms involved in protein synthesis machinery as a new tool for the control of cell proliferation.

artículo científico publicado en 2000

Modulation of pancreatic cancer chemoresistance by inhibition of TAK1

artículo científico publicado en 2011

Molecular dynamics simulation and automated docking of the pro-apoptotic Bax protein and its complex with a peptide designed from the Bax-binding domain of anti-apoptotic Ku70

artículo científico publicado en 2006

Molecular genetics of cancer. Oncogenes and tumor suppressor genes

artículo científico publicado en 1995

Multidisciplinary approach to rectal cancer: are we ready for selective treatment strategies?

artículo científico publicado en 2013

Multiple-target drugs: inhibitors of heat shock protein 90 and of histone deacetylase.

artículo científico publicado en 2005

New Prognostic and Predictive Markers in Cancer Progression

artículo científico publicado en 2020

New perspective for an old antidiabetic drug: metformin as anticancer agent.

artículo científico publicado en 2014

New pharmacokinetic and pharmacodynamic tools for interferon-alpha (IFN-alpha) treatment of human cancer.

artículo científico publicado en 2005

Novel pathways involved in cisplatin resistance identified by a proteomics approach in non-small-cell lung cancer cells

artículo científico publicado en 2018

Oxaliplatin Plus Dual Inhibition of Thymidilate Synthase During Preoperative Pelvic Radiotherapy for Locally Advanced Rectal Carcinoma: Long-Term Outcome

scientific article published on 14 May 2010

Oxidative Stress Gene Expression Profile Correlates with Cancer Patient Poor Prognosis: Identification of Crucial Pathways Might Select Novel Therapeutic Approaches.

artículo científico publicado en 2017

Pancreatic cancer: between bench and bedside

scientific article published on 01 June 2012

Panobinostat synergizes with zoledronic acid in prostate cancer and multiple myeloma models by increasing ROS and modulating mevalonate and p38-MAPK pathways.

scientific article published on 24 October 2013

Pathophysiologically relevant in vitro tumor models for drug screening

artículo científico

Perspectives in melanoma: meeting report from the Melanoma Bridge (November 29th-1 December 1st, 2018, Naples, Italy)

artículo científico publicado en 2019

Pharmacological targeting of p53 through RITA is an effective antitumoral strategy for malignant pleural mesothelioma

artículo científico publicado en 2013

Phase 1/2 study of valproic acid and short-course radiotherapy plus capecitabine as preoperative treatment in low-moderate risk rectal cancer-V-shoRT-R3 (Valproic acid--short Radiotherapy--rectum 3rd trial).

artículo científico publicado en 2014

Phase I and pharmacokinetic study of tomudex combined with 5-fluorouracil plus levofolinic acid in advanced head and neck cancer and colorectal cancer

artículo científico publicado en 1999

Phase I study of Caelyx (doxorubicin HCL, pegylated liposomal) in recurrent or metastatic head and neck cancer

artículo científico publicado en 2000

Phase II clinical study of valproic acid plus cisplatin and cetuximab in recurrent and/or metastatic squamous cell carcinoma of Head and Neck-V-CHANCE trial

artículo científico publicado en 2016

Phase II studies of anticancer chemotherapy: indirect evidence of poor quality

artículo científico publicado en 2006

Phase II study of temozolomide plus pegylated liposomal doxorubicin in the treatment of brain metastases from solid tumours

artículo científico publicado en 2005

Point mutation of the autophosphorylation site or in the nuclear location signal causes protein kinase A RII beta regulatory subunit to lose its ability to revert transformed fibroblasts

artículo científico publicado en 1995

Post-translational modifications of eukaryotic initiation factor-5A (eIF-5A) as a new target for anti-cancer therapy

scientific article published on 01 January 1999

Proteomic analysis identifies differentially expressed proteins after HDAC vorinostat and EGFR inhibitor gefitinib treatments in Hep-2 cancer cells.

artículo científico publicado en 2011

Proteomic characterization of peroxisome proliferator-activated receptor-γ (PPARγ) overexpressing or silenced colorectal cancer cells unveils a novel protein network associated with an aggressive phenotype.

artículo científico publicado en 2016

Proteomic screening identifies calreticulin as a miR-27a direct target repressing MHC class I cell surface exposure in colorectal cancer

artículo científico publicado en 2016

R115777 (Zarnestra)/Zoledronic acid (Zometa) cooperation on inhibition of prostate cancer proliferation is paralleled by Erk/Akt inactivation and reduced Bcl-2 and bad phosphorylation

artículo científico publicado en 2007

Randomized phase II study of valproic acid in combination with bevacizumab and oxaliplatin/fluoropyrimidine regimens in patients with RAS-mutated metastatic colorectal cancer: the REVOLUTION study protocol

scientific article published on 11 August 2020

Reprogramming miRNAs global expression orchestrates development of drug resistance in BRAF mutated melanoma

scientific article published on 25 September 2018

Restoring p53 function in cancer: novel therapeutic approaches for applying the brakes to tumorigenesis

artículo científico publicado en 2010

Sequential PET/CT with [18F]-FDG Predicts Pathological Tumor Response to Preoperative Short Course Radiotherapy with Delayed Surgery in Patients with Locally Advanced Rectal Cancer Using Logistic Regression Analysis

artículo científico publicado en 2017

Small tumor of the medial breast presenting with a contralateral lymph node involvement detected on positron emission tomography scan.

artículo científico publicado en 2007

Somatostatin analogues, a series of tissue transglutaminase inducers, as a new tool for therapy of mesenchimal tumors of the gastrointestinal tract

scientific article published on 06 February 2007

Stearoyl-CoA-desaturase 1 regulates lung cancer stemness via stabilization and nuclear localization of YAP/TAZ.

artículo científico publicado en 2017

Structure-function relationship of an Urokinase Receptor-derived peptide which inhibits the Formyl Peptide Receptor type 1 activity

scientific article published on 21 August 2019

Synergistic antitumor activity of epidermal growth factor receptor tyrosine kinase inhibitor gefitinib and IFN-alpha in head and neck cancer cells in vitro and in vivo

artículo científico publicado en 2006

Synergistic antitumor activity of histone deacetylase inhibitors and anti-ErbB3 antibody in NSCLC primary cultures via modulation of ErbB receptors expression.

artículo científico publicado en 2016

Synergistic antitumor interaction between valproic acid and capecitabine in breast cancer.

artículo científico publicado en 2015

Synergistic antitumor interaction between valproic acid, capecitabine and radiotherapy in colorectal cancer: critical role of p53.

artículo científico publicado en 2017

Synergistic antitumor interaction of valproic acid and simvastatin sensitizes prostate cancer to docetaxel by targeting CSCs compartment via YAP inhibition

artículo científico publicado en 2020

Synergistic inhibition of pancreatic adenocarcinoma cell growth by trichostatin A and gemcitabine.

artículo científico publicado en 2007

Synthesis of 1-naphtylpiperazine derivatives as serotoninergic ligands and their evaluation as antiproliferative agents

scientific article published on 08 March 2011

Synthesis of Arylpiperazine Derivatives as Protease Activated Receptor 1 Antagonists and Their Evaluation as Antiproliferative Agents.

artículo científico publicado en 2016

Targeting Mevalonate Pathway in Cancer Treatment: Repurposing of Statins.

artículo científico publicado en 2017

Targeting Raf-kinase: molecular rationales and translational issues.

artículo científico publicado en 2006

Targeting thymidylate synthase in colorectal cancer: critical re-evaluation and emerging therapeutic role of raltitrexed

artículo científico publicado en 2013

The Crosstalk between Cancer Stem Cells and Microenvironment Is Critical for Solid Tumor Progression: The Significant Contribution of Extracellular Vesicles

artículo científico publicado en 2018

The Effect of Light Exposure at Night (LAN) on Carcinogenesis via Decreased Nocturnal Melatonin Synthesis

artículo científico publicado en 2018

The PPAR-γ agonist troglitazone antagonizes survival pathways induced by STAT-3 in recombinant interferon-β treated pancreatic cancer cells.

artículo científico publicado en 2011

The clinical response on bone metastasis from breast and lung cancer during treatment with zoledronic acid is inversely correlated to skeletal related events (SRE).

artículo científico publicado en 2007

The farnesyl transferase inhibitor R115777 (Zarnestra) synergistically enhances growth inhibition and apoptosis induced on epidermoid cancer cells by Zoledronic acid (Zometa) and Pamidronate

artículo científico publicado en 2004

The farnesyltransferase inhibitor R115777 (ZARNESTRA) enhances the pro-apoptotic activity of interferon-alpha through the inhibition of multiple survival pathways

artículo científico publicado en 2007

The immunomodulatory protein SV-IV protects serum-deprived cells against apoptosis but not against G0/G1 arrest: possible implications for the survival of implanting embryo

artículo científico publicado en 2007

The miR-27a-calreticulin axis affects drug-induced immunogenic cell death in human colorectal cancer cells

artículo científico publicado en 2016

The primary occurrence of BRAF(V600E) is a rare clonal event in papillary thyroid carcinoma.

artículo científico publicado en 2011

The role of eukaryotic initiation factor 5A in the control of cell proliferation and apoptosis.

artículo científico publicado en 2001

Tissue transglutaminase (TG2) is involved in the resistance of cancer cells to the histone deacetylase (HDAC) inhibitor vorinostat.

artículo científico publicado en 2016

Toxigenic effects of two benthic diatoms upon grazing activity of the sea urchin: morphological, metabolomic and de novo transcriptomic analysis.

artículo científico publicado en 2018

Translational and post-translational modifications of proteins as a new mechanism of action of alpha-interferon: review article.

artículo científico publicado en 2004

Up-regulated EGF receptors undergo to rapid internalization and ubiquitin-dependent degradation in human cancer cells exposed to 8-Cl-cAMP

artículo científico publicado en 1999

Urotensin II receptor predicts the clinical outcome of prostate cancer patients and is involved in the regulation of motility of prostate adenocarcinoma cells

artículo científico publicado en 2011

Valproic acid potentiates the anticancer activity of capecitabine in vitro and in vivo in breast cancer models via induction of thymidine phosphorylase expression.

artículo científico publicado en 2015

Vorinostat Potentiates 5-Fluorouracil/Cisplatin Combination by Inhibiting Chemotherapy-Induced EGFR Nuclear Translocation and Increasing Cisplatin Uptake

artículo científico publicado en 2019

Vorinostat synergises with capecitabine through upregulation of thymidine phosphorylase.

artículo científico publicado en 2010

Vorinostat synergizes with EGFR inhibitors in NSCLC cells by increasing ROS via up-regulation of the major mitochondrial porin VDAC1 and modulation of the c-Myc-NRF2-KEAP1 pathway

artículo científico publicado en 2015

Weekly paclitaxel-cisplatin administration with G-CSF support in advanced breast cancer. A phase II study

artículo científico publicado el 1 de mayo de 1998

alpha-Interferon potentiates epidermal growth factor receptor-mediated effects on human epidermoid carcinoma KB cells

artículo científico publicado en 1995

cAMP-dependent protein kinase: role in normal and malignant growth.

artículo científico publicado en 1995