Lista de obras - Kai Breuhahn - Dominio Público Uruguay

A Systems Biology Study on NFκB Signaling in Primary Mouse Hepatocytes

artículo científico publicado en 2012

A cellular view of Nf2 in liver homeostasis and tumorigenesis

scientific article published on 01 September 2010

AP-1-controlled hepatocyte growth factor activation promotes keratinocyte migration via CEACAM1 and urokinase plasminogen activator/urokinase plasminogen receptor

artículo científico publicado en 2008

Acquired Resistance to Antiangiogenic Therapies in Hepatocellular Carcinoma Is Mediated by Yes-Associated Protein 1 Activation and Transient Expansion of Stem-Like Cancer Cells

artículo científico publicado en 2021

Analysis of UVB‐modulated Gene Expression in Human Keratinocytes by mRNA Differential Display Polymerase Chain Reaction ⬇️

artículo científico publicado el 1 de septiembre de 1997

Autocrine insulin-like growth factor-II stimulation of tumor cell migration is a progression step in human hepatocarcinogenesis

artículo científico publicado en 2008

Beta-catenin accumulation in the progression of human hepatocarcinogenesis correlates with loss of E-cadherin and accumulation of p53, but not with expression of conventional WNT-1 target genes.

artículo científico publicado en 2003

Cellular apoptosis susceptibility (CAS) is linked to integrin β1 and required for tumor cell migration and invasion in hepatocellular carcinoma (HCC).

artículo científico publicado en 2016

Cellular apoptosis susceptibility (CAS) is overexpressed in thyroid carcinoma and maintains tumor cell growth: A potential link to the BRAFV600E mutation

artículo científico publicado en 2016

Chromosome 8p tumor suppressor genes SH2D4A and SORBS3 cooperate to inhibit interleukin-6 signaling in hepatocellular carcinoma

artículo científico publicado en 2016

Chromosome alterations in human hepatocellular carcinomas correlate with aetiology and histological grade--results of an explorative CGH meta-analysis

artículo científico publicado en 2005

Comparative analysis of TGF-β/Smad signaling dependent cytostasis in human hepatocellular carcinoma cell lines

artículo científico publicado en 2013

Concomitant expression of far upstream element (FUSE) binding protein (FBP) interacting repressor (FIR) and its splice variants induce migration and invasion of non-small cell lung cancer (NSCLC) cells

artículo científico publicado en 2015

Coordinated expression of stathmin family members by far upstream sequence element-binding protein-1 increases motility in non-small cell lung cancer

artículo científico publicado en 2009

Correction: Stathmin Regulates Keratinocyte Proliferation and Migration during Cutaneous Regeneration

artículo científico publicado en 2013

Curcumin effectively inhibits oncogenic NF-κB signaling and restrains stemness features in liver cancer

artículo científico publicado en 2015

Cyclooxygenase-2 inhibition induces apoptosis signaling via death receptors and mitochondria in hepatocellular carcinoma

artículo científico publicado en 2006

Cyclooxygenase-2 inhibitors suppress the growth of human hepatocellular carcinoma implants in nude mice

artículo científico publicado en 2004

Cytoplasmic localization of the cell polarity factor Scribble supports liver tumor formation and tumor cell invasiveness.

artículo científico publicado en 2017

Cytosolic and nuclear caspase-8 have opposite impact on survival after liver resection for hepatocellular carcinoma

artículo científico publicado en 2013

Directed random walks and constraint programming reveal active pathways in hepatocyte growth factor signaling.

artículo científico publicado en 2015

Down-regulation of tumor suppressor A kinase anchor protein 12 in human hepatocarcinogenesis by epigenetic mechanisms

artículo científico publicado en 2010

Downregulation of the activating NKp30 ligand B7-H6 by HDAC inhibitors impairs tumor cell recognition by NK cells

artículo científico publicado en 2013

Dysregulation of growth factor signaling in human hepatocellular carcinoma.

artículo científico publicado en 2006

Elevated expression of c-kit in small venous malformations of blue rubber bleb nevus syndrome ⬇️

artículo científico publicado en 2010

Endothelial plasticity governs the site-specific leukocyte recruitment in hepatocellular cancer

artículo científico publicado en 2013

Endothelial transdifferentiation in hepatocellular carcinoma: loss of Stabilin-2 expression in peri-tumourous liver correlates with increased survival.

artículo científico publicado en 2013

Epidermal overexpression of granulocyte-macrophage colony-stimulating factor induces both keratinocyte proliferation and apoptosis

artículo científico publicado en 2000

Epidermal-specific deletion of CD44 reveals a function in keratinocytes in response to mechanical stress.

artículo científico publicado en 2016

Ex vivo analysis of antineoplastic agents in precision-cut tissue slices of human origin: effects of cyclooxygenase-2 inhibition in hepatocellular carcinoma

artículo científico publicado en 2006

Expression of cyclooxygenase-2 (COX-2) in an advanced metastasized hypopharyngeal carcinoma and cultured tumor cells.

artículo científico publicado en 2010

Expression of epithelial cellular adhesion molecule (Ep-CAM) in chronic (necro-)inflammatory liver diseases and hepatocellular carcinoma

scientific article published on 20 December 2005

Factors of transforming growth factor beta signalling are co-regulated in human hepatocellular carcinoma

scientific article published on 29 September 2004

Gene network dynamics controlling keratinocyte migration

artículo científico publicado en 2008

Global alterations of DNA methylation in cholangiocarcinoma target the Wnt signaling pathway

artículo científico publicado en 2013

High-fat intake during pregnancy and lactation exacerbates high-fat diet-induced complications in male offspring in mice.

artículo científico publicado en 2013

Human and mouse VEGFA-amplified hepatocellular carcinomas are highly sensitive to sorafenib treatment.

artículo científico publicado en 2014

Imbalance of DNA-dependent protein kinase subunits in polycythemia vera peripheral blood stem cells.

artículo científico publicado en 2009

Inducing Differentiation of Premalignant Hepatic Cells as a Novel Therapeutic Strategy in Hepatocarcinoma

artículo científico publicado en 2016

Induction of Chromosome Instability by Activation of Yes-Associated Protein and Forkhead Box M1 in Liver Cancer.

artículo científico publicado en 2017

Insulin-like growth factor (IGF)-signalling pathway components are potential therapeutic targets in the treatment of human hepatocellular carcinoma

artículo científico publicado en 2007

Insulin-like growth factor 2 mRNA-binding protein 1 (IGF2BP1) is an important protumorigenic factor in hepatocellular carcinoma

article

Insulin-like growth factor II mRNA-binding protein 3 (IMP3) expression in hepatocellular carcinoma. A clinicopathological analysis with emphasis on diagnostic value.

artículo científico publicado en 2012

Insulin/IGF signaling drives cell proliferation in part via Yorkie/YAP.

artículo científico publicado en 2012

Kallikrein 6 induces E-cadherin shedding and promotes cell proliferation, migration, and invasion

scientific article published on 01 September 2007

Keratinocyte-derived granulocyte-macrophage colony stimulating factor accelerates wound healing: Stimulation of keratinocyte proliferation, granulation tissue formation, and vascularization

artículo científico publicado en 2001

Large-scale N-terminal deletions but not point mutations stabilize beta-catenin in small bowel carcinomas, suggesting divergent molecular pathways of small and large intestinal carcinogenesis.

artículo científico publicado en 2008

Lipid droplet-associated PAT-proteins show frequent and differential expression in neoplastic steatogenesis.

artículo científico publicado en 2010

MicroRNAs are key regulators of hepatocellular carcinoma (HCC) cell dissemination-what we learned from microRNA-494.

artículo científico publicado en 2016

Molecular mechanisms of progression in human hepatocarcinogenesis

artículo científico publicado en 2010

Molecular pathogenesis of human hepatocellular carcinoma

artículo científico publicado en 2002

Molecular profiling of human hepatocellular carcinoma defines mutually exclusive interferon regulation and insulin-like growth factor II overexpression

artículo científico publicado en 2004

Non-specific effects of siRNAs on tumor cells with implications on therapeutic applicability using RNA interference

artículo científico publicado en 2007

Nuclear accumulation of seven in absentia homologue-2 supports motility and proliferation of liver cancer cells.

artículo científico publicado en 2012

Nuclear expression of the deubiquitinase CYLD is associated with improved survival in human hepatocellular carcinoma

artículo científico publicado en 2014

Nuclear expression of the ubiquitin ligase seven in absentia homolog (SIAH)-1 induces proliferation and migration of liver cancer cells

artículo científico publicado en 2011

Nuclear pore component Nup98 is a potential tumor suppressor and regulates posttranscriptional expression of select p53 target genes

artículo científico publicado en 2012

Nucleoporin 88 expression in hepatitis B and C virus-related liver diseases

artículo científico publicado en 2006

On the ontology based representation of cell lines

artículo científico publicado en 2012

Oncogenetic tree modeling of human hepatocarcinogenesis

artículo científico publicado en 2011

Overexpression of far upstream element (FUSE) binding protein (FBP)-interacting repressor (FIR) supports growth of hepatocellular carcinoma.

artículo científico publicado en 2014

PI3K/AKT/mTOR-dependent stabilization of oncogenic far-upstream element binding proteins in hepatocellular carcinoma cells.

scientific article published on 14 January 2016

Patch-Based Nonlinear Image Registration for Gigapixel Whole Slide Images

artículo científico publicado en 2015

Podocalyxin-like protein 1 expression in primary hepatic tumours and tumour-like lesions

scientific article published on 01 September 2006

Posttranscriptional destabilization of the liver-specific long noncoding RNA HULC by the IGF2 mRNA-binding protein 1 (IGF2BP1).

artículo científico publicado en 2013

Proapoptotic and antiproliferative potential of selective cyclooxygenase-2 inhibitors in human liver tumor cells

artículo científico publicado en 2002

Proinflammatory cytokines cause FAT10 upregulation in cancers of liver and colon

artículo científico publicado en 2008

Prosurvival function of the cellular apoptosis susceptibility/importin-α1 transport cycle is repressed by p53 in liver cancer.

artículo científico publicado en 2014

Proteomic Analysis Reveals GMP Synthetase as p53 Repression Target in Liver Cancer

artículo científico publicado en 2016

Protumorigenic overexpression of stathmin/Op18 by gain-of-function mutation in p53 in human hepatocarcinogenesis.

artículo científico publicado en 2007

Quantitative analysis of gene expression relative to 18S rRNA in carcinoma samples using the LightCycler instrument and a SYBR GreenI-based assay: determining FAT10 mRNA levels in hepatocellular carcinoma

artículo científico publicado en 2008

Quantitative and integrative analysis of paracrine hepatocyte activation by nonparenchymal cells upon lipopolysaccharide induction

artículo científico publicado en 2017

Rapamycin delays tumor development in murine livers by inhibiting proliferation of hepatocytes with DNA damage.

artículo científico publicado en 2009

Reactivation of the insulin-like growth factor-II signaling pathway in human hepatocellular carcinoma.

artículo científico publicado en 2008

S100A8 and S100A9 are novel nuclear factor kappa B target genes during malignant progression of murine and human liver carcinogenesis.

artículo científico publicado en 2009

SKP2 cooperates with N-Ras or AKT to induce liver tumor development in mice

artículo científico publicado en 2015

Signaling Networks in Human Hepatocarcinogenesis—Novel Aspects and Therapeutic Options

artículo científico publicado el 1 de enero de 2010

Stathmin regulates keratinocyte proliferation and migration during cutaneous regeneration

artículo científico publicado en 2013

Strategies for hepatocellular carcinoma therapy and diagnostics: lessons learned from high throughput and profiling approaches.

scientific article published on June 2011

TTCA: an R package for the identification of differentially expressed genes in time course microarray data

artículo científico publicado en 2017

The cyclin E regulator cullin 3 prevents mouse hepatic progenitor cells from becoming tumor-initiating cells

artículo científico publicado en 2010

The designer cytokine hyper-IL-6 mediates growth inhibition and GM-CSF-dependent rejection of B16 melanoma cells

artículo científico publicado en 2001

The proto-oncogene Myc drives expression of the NK cell-activating NKp30 ligand B7-H6 in tumor cells.

artículo científico publicado en 2016

The transcriptional coactivators megakaryoblastic leukemia 1/2 mediate the effects of loss of the tumor suppressor deleted in liver cancer 1.

artículo científico publicado en 2011

Transcriptional regulators in hepatocarcinogenesis--key integrators of malignant transformation.

artículo científico

Tumor cell load and heterogeneity estimation from diffusion-weighted MRI calibrated with histological data: an example from lung cancer.

artículo científico publicado en 2017

UVB-regulated gene expression in human keratinocytes. Analysis by differential display.

artículo científico publicado en 2000

Up- and down-regulation of granulocyte/macrophage-colony stimulating factor activity in murine skin increase susceptibility to skin carcinogenesis by independent mechanisms.

artículo científico publicado en 2001

Wound healing revised: a novel reepithelialization mechanism revealed by in vitro and in silico models.

artículo científico publicado en 2013

Yes-associated protein (YAP) induces a secretome phenotype and transcriptionally regulates plasminogen activator Inhibitor-1 (PAI-1) expression in hepatocarcinogenesis

artículo científico publicado en 2020

[Insulin-like growth factor (IGF)-II in human hepatocarcinogenesis--a potential therapeutic target?]

scientific article published on 01 January 2005

[Molecular pathogenesis of hepatocellular carcinoma: new therapeutic approaches and predictive pathology]

artículo científico publicado en 2007

[Reduced expression of the E3-ubiquitin ligase seven in absentia homologue (SIAH)-1 in human hepatocellular carcinoma]

artículo científico publicado en 2007

miR-615-5p is restrictedly expressed in cirrhotic and cancerous liver tissues and its overexpression alleviates the tumorigenic effects in hepatocellular carcinoma.

artículo científico publicado en 2012

Lista de obras de Kai Breuhahn

A Systems Biology Study on NFκB Signaling in Primary Mouse Hepatocytes

A cellular view of Nf2 in liver homeostasis and tumorigenesis

AP-1-controlled hepatocyte growth factor activation promotes keratinocyte migration via CEACAM1 and urokinase plasminogen activator/urokinase plasminogen receptor

Acquired Resistance to Antiangiogenic Therapies in Hepatocellular Carcinoma Is Mediated by Yes-Associated Protein 1 Activation and Transient Expansion of Stem-Like Cancer Cells

Analysis of UVB‐modulated Gene Expression in Human Keratinocytes by mRNA Differential Display Polymerase Chain Reaction ⬇️

Autocrine insulin-like growth factor-II stimulation of tumor cell migration is a progression step in human hepatocarcinogenesis

Beta-catenin accumulation in the progression of human hepatocarcinogenesis correlates with loss of E-cadherin and accumulation of p53, but not with expression of conventional WNT-1 target genes.

Cellular apoptosis susceptibility (CAS) is linked to integrin β1 and required for tumor cell migration and invasion in hepatocellular carcinoma (HCC).

Cellular apoptosis susceptibility (CAS) is overexpressed in thyroid carcinoma and maintains tumor cell growth: A potential link to the BRAFV600E mutation

Chromosome 8p tumor suppressor genes SH2D4A and SORBS3 cooperate to inhibit interleukin-6 signaling in hepatocellular carcinoma

Chromosome alterations in human hepatocellular carcinomas correlate with aetiology and histological grade--results of an explorative CGH meta-analysis

Comparative analysis of TGF-β/Smad signaling dependent cytostasis in human hepatocellular carcinoma cell lines

Concomitant expression of far upstream element (FUSE) binding protein (FBP) interacting repressor (FIR) and its splice variants induce migration and invasion of non-small cell lung cancer (NSCLC) cells

Coordinated expression of stathmin family members by far upstream sequence element-binding protein-1 increases motility in non-small cell lung cancer

Correction: Stathmin Regulates Keratinocyte Proliferation and Migration during Cutaneous Regeneration

Curcumin effectively inhibits oncogenic NF-κB signaling and restrains stemness features in liver cancer

Cyclooxygenase-2 inhibition induces apoptosis signaling via death receptors and mitochondria in hepatocellular carcinoma

Cyclooxygenase-2 inhibitors suppress the growth of human hepatocellular carcinoma implants in nude mice

Cytoplasmic localization of the cell polarity factor Scribble supports liver tumor formation and tumor cell invasiveness.

Cytosolic and nuclear caspase-8 have opposite impact on survival after liver resection for hepatocellular carcinoma

Directed random walks and constraint programming reveal active pathways in hepatocyte growth factor signaling.

Down-regulation of tumor suppressor A kinase anchor protein 12 in human hepatocarcinogenesis by epigenetic mechanisms

Downregulation of the activating NKp30 ligand B7-H6 by HDAC inhibitors impairs tumor cell recognition by NK cells

Dysregulation of growth factor signaling in human hepatocellular carcinoma.

Elevated expression of c-kit in small venous malformations of blue rubber bleb nevus syndrome ⬇️

Endothelial plasticity governs the site-specific leukocyte recruitment in hepatocellular cancer

Endothelial transdifferentiation in hepatocellular carcinoma: loss of Stabilin-2 expression in peri-tumourous liver correlates with increased survival.

Epidermal overexpression of granulocyte-macrophage colony-stimulating factor induces both keratinocyte proliferation and apoptosis

Epidermal-specific deletion of CD44 reveals a function in keratinocytes in response to mechanical stress.

Ex vivo analysis of antineoplastic agents in precision-cut tissue slices of human origin: effects of cyclooxygenase-2 inhibition in hepatocellular carcinoma

Expression of cyclooxygenase-2 (COX-2) in an advanced metastasized hypopharyngeal carcinoma and cultured tumor cells.

Expression of epithelial cellular adhesion molecule (Ep-CAM) in chronic (necro-)inflammatory liver diseases and hepatocellular carcinoma

Factors of transforming growth factor beta signalling are co-regulated in human hepatocellular carcinoma

Gene network dynamics controlling keratinocyte migration

Global alterations of DNA methylation in cholangiocarcinoma target the Wnt signaling pathway

High-fat intake during pregnancy and lactation exacerbates high-fat diet-induced complications in male offspring in mice.

Human and mouse VEGFA-amplified hepatocellular carcinomas are highly sensitive to sorafenib treatment.

Imbalance of DNA-dependent protein kinase subunits in polycythemia vera peripheral blood stem cells.

Inducing Differentiation of Premalignant Hepatic Cells as a Novel Therapeutic Strategy in Hepatocarcinoma

Induction of Chromosome Instability by Activation of Yes-Associated Protein and Forkhead Box M1 in Liver Cancer.

Insulin-like growth factor (IGF)-signalling pathway components are potential therapeutic targets in the treatment of human hepatocellular carcinoma

Insulin-like growth factor 2 mRNA-binding protein 1 (IGF2BP1) is an important protumorigenic factor in hepatocellular carcinoma

Insulin-like growth factor II mRNA-binding protein 3 (IMP3) expression in hepatocellular carcinoma. A clinicopathological analysis with emphasis on diagnostic value.

Insulin/IGF signaling drives cell proliferation in part via Yorkie/YAP.

Kallikrein 6 induces E-cadherin shedding and promotes cell proliferation, migration, and invasion

Keratinocyte-derived granulocyte-macrophage colony stimulating factor accelerates wound healing: Stimulation of keratinocyte proliferation, granulation tissue formation, and vascularization

Large-scale N-terminal deletions but not point mutations stabilize beta-catenin in small bowel carcinomas, suggesting divergent molecular pathways of small and large intestinal carcinogenesis.

Lipid droplet-associated PAT-proteins show frequent and differential expression in neoplastic steatogenesis.

MicroRNAs are key regulators of hepatocellular carcinoma (HCC) cell dissemination-what we learned from microRNA-494.

Molecular mechanisms of progression in human hepatocarcinogenesis

Molecular pathogenesis of human hepatocellular carcinoma

Molecular profiling of human hepatocellular carcinoma defines mutually exclusive interferon regulation and insulin-like growth factor II overexpression

Non-specific effects of siRNAs on tumor cells with implications on therapeutic applicability using RNA interference

Nuclear accumulation of seven in absentia homologue-2 supports motility and proliferation of liver cancer cells.

Nuclear expression of the deubiquitinase CYLD is associated with improved survival in human hepatocellular carcinoma

Nuclear expression of the ubiquitin ligase seven in absentia homolog (SIAH)-1 induces proliferation and migration of liver cancer cells

Nuclear pore component Nup98 is a potential tumor suppressor and regulates posttranscriptional expression of select p53 target genes

Nucleoporin 88 expression in hepatitis B and C virus-related liver diseases

On the ontology based representation of cell lines

Oncogenetic tree modeling of human hepatocarcinogenesis

Overexpression of far upstream element (FUSE) binding protein (FBP)-interacting repressor (FIR) supports growth of hepatocellular carcinoma.

PI3K/AKT/mTOR-dependent stabilization of oncogenic far-upstream element binding proteins in hepatocellular carcinoma cells.

Patch-Based Nonlinear Image Registration for Gigapixel Whole Slide Images

Podocalyxin-like protein 1 expression in primary hepatic tumours and tumour-like lesions

Posttranscriptional destabilization of the liver-specific long noncoding RNA HULC by the IGF2 mRNA-binding protein 1 (IGF2BP1).

Proapoptotic and antiproliferative potential of selective cyclooxygenase-2 inhibitors in human liver tumor cells

Proinflammatory cytokines cause FAT10 upregulation in cancers of liver and colon

Prosurvival function of the cellular apoptosis susceptibility/importin-α1 transport cycle is repressed by p53 in liver cancer.

Proteomic Analysis Reveals GMP Synthetase as p53 Repression Target in Liver Cancer

Protumorigenic overexpression of stathmin/Op18 by gain-of-function mutation in p53 in human hepatocarcinogenesis.

Quantitative analysis of gene expression relative to 18S rRNA in carcinoma samples using the LightCycler instrument and a SYBR GreenI-based assay: determining FAT10 mRNA levels in hepatocellular carcinoma

Quantitative and integrative analysis of paracrine hepatocyte activation by nonparenchymal cells upon lipopolysaccharide induction

Rapamycin delays tumor development in murine livers by inhibiting proliferation of hepatocytes with DNA damage.

Reactivation of the insulin-like growth factor-II signaling pathway in human hepatocellular carcinoma.

S100A8 and S100A9 are novel nuclear factor kappa B target genes during malignant progression of murine and human liver carcinogenesis.

SKP2 cooperates with N-Ras or AKT to induce liver tumor development in mice

Signaling Networks in Human Hepatocarcinogenesis—Novel Aspects and Therapeutic Options

Stathmin regulates keratinocyte proliferation and migration during cutaneous regeneration

Strategies for hepatocellular carcinoma therapy and diagnostics: lessons learned from high throughput and profiling approaches.