Lista de obras - Resat Cinar - Dominio Público Uruguay

Activation of the Nlrp3 inflammasome in infiltrating macrophages by endocannabinoids mediates beta cell loss in type 2 diabetes

artículo científico publicado en 2013

Alcohol Binge-Induced Cardiovascular Dysfunction Involves Endocannabinoid-CB1-R Signaling

scientific article published on 23 September 2019

Bleomycin Induces Drug Efflux in Lungs. A Pitfall for Pharmacological Studies of Pulmonary Fibrosis

artículo científico publicado en 2020

CB1 receptor-independent actions of SR141716 on G-protein signaling: coapplication with the mu-opioid agonist Tyr-D-Ala-Gly-(NMe)Phe-Gly-ol unmasks novel, pertussis toxin-insensitive opioid signaling in mu-opioid receptor-Chinese hamster ovary cells

artículo científico publicado en 2009

Cannabinoid 1 receptor promotes cardiac dysfunction, oxidative stress, inflammation, and fibrosis in diabetic cardiomyopathy

artículo científico publicado en 2012

Cannabinoid CB1 receptor overactivity contributes to the pathogenesis of idiopathic pulmonary fibrosis

artículo científico publicado en 2017

Cannabinoid receptor 1 promotes hepatocellular carcinoma initiation and progression through multiple mechanisms

artículo científico publicado en 2015

Cannabinoid receptor signaling regulates liver development and metabolism

artículo científico publicado en 2016

Cannabinoid-1 Receptor Antagonism Improves Glycemic Control and Increases Energy Expenditure via Sirt1/mTORC2 and AMPK Signaling

artículo científico publicado en 2019

Cannabinoid-1 receptor deletion in podocytes mitigates both glomerular and tubular dysfunction in a mouse model of diabetic nephropathy

artículo científico publicado en 2017

Characterization of heterogeneous redox responses in hepatocellular carcinoma patients using network analysis.

artículo científico publicado en 2018

Chronic alcohol produces neuroadaptations to prime dorsal striatal learning

artículo científico publicado en 2013

Convergent translational evidence of a role for anandamide in amygdala-mediated fear extinction, threat processing and stress-reactivity

artículo científico publicado en 2012

Crystal Structure of the Human Cannabinoid Receptor CB2

scientific article published on 10 January 2019

Decreasing CB1 receptor signaling in Kupffer cells improves insulin sensitivity in obese mice

artículo científico publicado en 2017

Design, Synthesis, and Biological Evaluation of Novel, Non-Brain-Penetrant, Hybrid Cannabinoid CB1R Inverse Agonist/Inducible Nitric Oxide Synthase (iNOS) Inhibitors for the Treatment of Liver Fibrosis.

artículo científico publicado en 2017

Developmental Role of Macrophage Cannabinoid-1 Receptor Signaling in Type 2 Diabetes

artículo científico publicado en 2017

Discovery of a NAPE-PLD inhibitor that modulates emotional behavior in mice

scientific article published on 11 May 2020

Disruption of renal arginine metabolism promotes kidney injury in hepatorenal syndrome.

artículo científico publicado en 2018

Dual inhibition of cannabinoid CB1 receptor and inducible NOS attenuates obesity-induced chronic kidney disease

scientific article published on 27 December 2019

Endocannabinoids in liver disease

artículo científico publicado en 2011

Feasibility Evaluation of Myocardial Cannabinoid Type 1 Receptor Imaging in Obesity: A Translational Approach.

artículo científico publicado en 2018

Fluoxetine Facilitates Fear Extinction Through Amygdala Endocannabinoids

artículo científico publicado en 2015

Hepatic cannabinoid-1 receptors mediate diet-induced insulin resistance by increasing de novo synthesis of long-chain ceramides

artículo científico publicado en 2013

Hybrid inhibitor of peripheral cannabinoid-1 receptors and inducible nitric oxide synthase mitigates liver fibrosis

artículo científico publicado en 2016

Hyperactivation of anandamide synthesis and regulation of cell-cycle progression via cannabinoid type 1 (CB1) receptors in the regenerating liver

artículo científico publicado en 2011

Inhibitor of fatty acid amide hydrolase normalizes cardiovascular function in hypertension without adverse metabolic effects

artículo científico publicado en 2010

Interplay of Liver-Heart Inflammatory Axis and Cannabinoid 2 Receptor Signaling in an Experimental Model of Hepatic Cardiomyopathy

artículo científico publicado en 2020

Lack of regulatory changes of µ-opioid receptors by 14-methoxymetopon treatment in rat brain. Further evidence for functional selectivity

artículo científico publicado en 2013

Ligand-specific regulation of the endogenous mu-opioid receptor by chronic treatment with mu-opioid peptide agonists

artículo científico publicado en 2013

Mice lacking GPR3 receptors display late-onset obese phenotype due to impaired thermogenic function in brown adipose tissue

artículo científico publicado en 2015

Monounsaturated fatty acids generated via stearoyl CoA desaturase-1 are endogenous inhibitors of fatty acid amide hydrolase

artículo científico publicado en 2013

Network analyses identify liver-specific targets for treating liver diseases

artículo científico publicado en 2017

Overactive cannabinoid 1 receptor in podocytes drives type 2 diabetic nephropathy

artículo científico publicado en 2014

Peripheral cannabinoid-1 receptor blockade restores hypothalamic leptin signaling

artículo científico publicado en 2017

Peripheral cannabinoid-1 receptor inverse agonism reduces obesity by reversing leptin resistance

artículo científico publicado en 2012

Proximal Tubular Cannabinoid-1 Receptor Regulates Obesity-Induced CKD.

artículo científico publicado en 2017

Reciprocal inhibition of G-protein signaling is induced by CB(1) cannabinoid and GABA(B) receptor interactions in rat hippocampal membranes

artículo científico publicado en 2008

Role of adiponectin in the metabolic effects of cannabinoid type 1 receptor blockade in mice with diet-induced obesity

artículo científico publicado en 2013

Stratification of Hepatocellular Carcinoma Patients Based on Acetate Utilization

artículo científico publicado en 2015

Structural Basis of Species-Dependent Differential Affinity of 6-Alkoxy-5-Aryl-3-Pyridinecarboxamide Cannabinoid-1 Receptor Antagonists

artículo científico publicado en 2015

Synthesis of 13 C6 -labeled, dual-target inhibitor of cannabinoid-1 receptor (CB1 R) and inducible nitric oxide synthase (iNOS)

artículo científico publicado en 2018

Synthesis of S-2-((S)-3-(4-chlorophenyl)-N'-((4-chlorophenyl)sulfonyl)-4-phenyl-4,5-dihydro-1H-pyrazole-1-carboximidamido)-3-(methyl-d3 )butanamide-d5 , octadeuterated JD5037.

artículo científico publicado en 2017

Synthetic cannabinoids induce acute lung inflammation via cannabinoid receptor 1 activation

artículo científico publicado en 2020

Targeting the endocannabinoid/CB1 receptor system for treating obesity in Prader-Willi syndrome

artículo científico publicado en 2016

The novel, orally available and peripherally restricted selective cannabinoid CB2 receptor agonist LEI-101 prevents cisplatin-induced nephrotoxicity

artículo científico publicado en 2015

β-Caryophyllene protects against alcoholic steatohepatitis by attenuating inflammation and metabolic dysregulation in mice

artículo científico publicado en 2017

Lista de obras de Resat Cinar

Activation of the Nlrp3 inflammasome in infiltrating macrophages by endocannabinoids mediates beta cell loss in type 2 diabetes

Alcohol Binge-Induced Cardiovascular Dysfunction Involves Endocannabinoid-CB1-R Signaling

Bleomycin Induces Drug Efflux in Lungs. A Pitfall for Pharmacological Studies of Pulmonary Fibrosis

CB1 receptor-independent actions of SR141716 on G-protein signaling: coapplication with the mu-opioid agonist Tyr-D-Ala-Gly-(NMe)Phe-Gly-ol unmasks novel, pertussis toxin-insensitive opioid signaling in mu-opioid receptor-Chinese hamster ovary cells

Cannabinoid 1 receptor promotes cardiac dysfunction, oxidative stress, inflammation, and fibrosis in diabetic cardiomyopathy

Cannabinoid CB1 receptor overactivity contributes to the pathogenesis of idiopathic pulmonary fibrosis

Cannabinoid receptor 1 promotes hepatocellular carcinoma initiation and progression through multiple mechanisms

Cannabinoid receptor signaling regulates liver development and metabolism

Cannabinoid-1 Receptor Antagonism Improves Glycemic Control and Increases Energy Expenditure via Sirt1/mTORC2 and AMPK Signaling

Cannabinoid-1 receptor deletion in podocytes mitigates both glomerular and tubular dysfunction in a mouse model of diabetic nephropathy

Characterization of heterogeneous redox responses in hepatocellular carcinoma patients using network analysis.

Chronic alcohol produces neuroadaptations to prime dorsal striatal learning

Convergent translational evidence of a role for anandamide in amygdala-mediated fear extinction, threat processing and stress-reactivity

Crystal Structure of the Human Cannabinoid Receptor CB2

Decreasing CB1 receptor signaling in Kupffer cells improves insulin sensitivity in obese mice

Design, Synthesis, and Biological Evaluation of Novel, Non-Brain-Penetrant, Hybrid Cannabinoid CB1R Inverse Agonist/Inducible Nitric Oxide Synthase (iNOS) Inhibitors for the Treatment of Liver Fibrosis.

Developmental Role of Macrophage Cannabinoid-1 Receptor Signaling in Type 2 Diabetes

Discovery of a NAPE-PLD inhibitor that modulates emotional behavior in mice

Disruption of renal arginine metabolism promotes kidney injury in hepatorenal syndrome.

Dual inhibition of cannabinoid CB1 receptor and inducible NOS attenuates obesity-induced chronic kidney disease

Endocannabinoids in liver disease

Feasibility Evaluation of Myocardial Cannabinoid Type 1 Receptor Imaging in Obesity: A Translational Approach.

Fluoxetine Facilitates Fear Extinction Through Amygdala Endocannabinoids

Hepatic cannabinoid-1 receptors mediate diet-induced insulin resistance by increasing de novo synthesis of long-chain ceramides

Hybrid inhibitor of peripheral cannabinoid-1 receptors and inducible nitric oxide synthase mitigates liver fibrosis

Hyperactivation of anandamide synthesis and regulation of cell-cycle progression via cannabinoid type 1 (CB1) receptors in the regenerating liver

Inhibitor of fatty acid amide hydrolase normalizes cardiovascular function in hypertension without adverse metabolic effects

Interplay of Liver-Heart Inflammatory Axis and Cannabinoid 2 Receptor Signaling in an Experimental Model of Hepatic Cardiomyopathy

Lack of regulatory changes of µ-opioid receptors by 14-methoxymetopon treatment in rat brain. Further evidence for functional selectivity

Ligand-specific regulation of the endogenous mu-opioid receptor by chronic treatment with mu-opioid peptide agonists

Mice lacking GPR3 receptors display late-onset obese phenotype due to impaired thermogenic function in brown adipose tissue

Monounsaturated fatty acids generated via stearoyl CoA desaturase-1 are endogenous inhibitors of fatty acid amide hydrolase

Network analyses identify liver-specific targets for treating liver diseases

Overactive cannabinoid 1 receptor in podocytes drives type 2 diabetic nephropathy

Peripheral cannabinoid-1 receptor blockade restores hypothalamic leptin signaling

Peripheral cannabinoid-1 receptor inverse agonism reduces obesity by reversing leptin resistance

Proximal Tubular Cannabinoid-1 Receptor Regulates Obesity-Induced CKD.

Reciprocal inhibition of G-protein signaling is induced by CB(1) cannabinoid and GABA(B) receptor interactions in rat hippocampal membranes

Role of adiponectin in the metabolic effects of cannabinoid type 1 receptor blockade in mice with diet-induced obesity

Stratification of Hepatocellular Carcinoma Patients Based on Acetate Utilization

Structural Basis of Species-Dependent Differential Affinity of 6-Alkoxy-5-Aryl-3-Pyridinecarboxamide Cannabinoid-1 Receptor Antagonists

Synthesis of 13 C6 -labeled, dual-target inhibitor of cannabinoid-1 receptor (CB1 R) and inducible nitric oxide synthase (iNOS)

Synthesis of S-2-((S)-3-(4-chlorophenyl)-N'-((4-chlorophenyl)sulfonyl)-4-phenyl-4,5-dihydro-1H-pyrazole-1-carboximidamido)-3-(methyl-d3 )butanamide-d5 , octadeuterated JD5037.

Synthetic cannabinoids induce acute lung inflammation via cannabinoid receptor 1 activation

Targeting the endocannabinoid/CB1 receptor system for treating obesity in Prader-Willi syndrome

The novel, orally available and peripherally restricted selective cannabinoid CB2 receptor agonist LEI-101 prevents cisplatin-induced nephrotoxicity

β-Caryophyllene protects against alcoholic steatohepatitis by attenuating inflammation and metabolic dysregulation in mice