Lista de obras - Franz König - Dominio Público Uruguay

"Threshold-crossing": A Useful Way to Establish the Counterfactual in Clinical Trials?

artículo científico publicado en 2016

A critical review of graphics for subgroup analyses in clinical trials

artículo científico publicado en 2020

A double-blind, randomized, placebo-controlled trial of intravenous L-ornithine-L-aspartate on postural control in patients with cirrhosis

artículo científico publicado en 2010

A multiple comparison procedure for dose-finding trials with subpopulations

artículo científico publicado en 2019

A proposal for a new PhD level curriculum on quantitative methods for drug development.

artículo científico publicado en 2018

A randomized controlled trial of alanyl-glutamine supplementation in peritoneal dialysis fluid to assess impact on biomarkers of peritoneal health

article

ABO antibody and complement depletion by immunoadsorption combined with membrane filtration--a randomized, controlled, cross-over trial

artículo científico publicado en 2013

Adaptive Dunnett tests for treatment selection

Adaptive clinical trial designs for European marketing authorization: a survey of scientific advice letters from the European Medicines Agency

artículo científico publicado en 2014

Adaptive designs for confirmatory clinical trials

artículo científico publicado en 2009

Adaptive designs for subpopulation analysis optimizing utility functions

artículo científico publicado en 2014

Adaptive graph-based multiple testing procedures

artículo científico publicado en 2014

Adaptive paediatric investigation plans, a small step to improve regulatory decision making in drug development for children?

artículo científico publicado en 2016

Aetiology of cirrhosis of the liver has an impact on survival predicted by the Model of End-stage Liver Disease score

artículo científico publicado en 2009

Allergen-specific nasal IgG antibodies induced by vaccination with genetically modified allergens are associated with reduced nasal allergen sensitivity

article by Jürgen Reisinger et al published August 2005 in The Journal of Allergy and Clinical Immunology

An Adaptive Hierarchical Test Procedure for Selecting Safe and Efficient Treatments

scientific article published on 01 August 2006

An integrated MELD model including serum sodium and age improves the prediction of early mortality in patients with cirrhosis.

artículo científico publicado en 2007

Authors' response to comments

artículo científico publicado en 2016

Bcl-2 expression as a novel immunohistochemical marker for ruptured tubal ectopic pregnancy

artículo científico publicado en 2001

Clearance of Selected Plasma Cytokines with Continuous Veno-Venous Hemodialysis Using Ultraflux EMiC2 versus Ultraflux AV1000S.

artículo científico publicado en 2017

Clinical trials for authorized biosimilars in the European Union: a systematic review

artículo científico publicado en 2016

Combination of anorganic bovine-derived hydroxyapatite with binding peptide does not enhance bone healing in a critical-size defect in a rabbit model

artículo científico publicado en 2008

Commentary: Two approaches to analyze platform trials incorporating non-concurrent controls with a common assumption

artículo científico publicado en 2022

Conditional Rejection Probabilities of Student'st-test and Design Adaptations

article by Martin Posch et al published August 2004 in Biometrical Journal

Confirmatory seamless phase II/III clinical trials with hypotheses selection at interim: general concepts

artículo científico publicado en 2006

Cytotoxic effects of dental bonding substances as a function of degree of conversion

artículo científico publicado en 2008

Cytotoxic effects of packable and nonpackable dental composites

artículo científico publicado en 2003

Cytotoxic effects of veneer composite materials.

artículo científico publicado en 2007

Cytotoxicity and shear bond strength of four orthodontic adhesive systems

artículo científico publicado en 2008

Cytotoxicity of a calcium aluminate cement in comparison with other dental cements and resin-based materials

artículo científico publicado en 2006

Cytotoxicity of four categories of dental cements.

artículo científico publicado en 2008

Cytotoxicity of resin composites as a function of interface area

artículo científico publicado en 2007

Degeneration and Instability and the Relation to Patients' Function Late After Lumbar Disc Surgery: Data from a 12-Year Follow-Up

artículo científico publicado en 2016

Delayed treatment effects, treatment switching and heterogeneous patient populations: How to design and analyze RCTs in oncology

scientific article published on 23 August 2020

Deprivation versus importation: a model explaining the increase of suicide rates in custody

artículo científico publicado en 2001

Development process of a consensus-driven CONSORT extension for randomised trials using an adaptive design

article by Munyaradzi Dimairo et al published 16 November 2018 in BMC Medicine

Diagnostic Contribution of Donor-Specific Antibody Characteristics to Uncover Late Silent Antibody-Mediated Rejection-Results of a Cross-Sectional Screening Study.

artículo científico publicado en 2016

Do monthly or seasonal variations exist in suicides in a high-risk setting?

artículo científico publicado en 2004

Effect of information on reported adverse events in a placebo-controlled trial

artículo científico publicado en 2005

Effects of a Femoral Shaft Fracture on Multiply Injured Patients with a Head Injury

Epidemiology of jail and prison suicides in Austria

scholarly article by Stefan Frühwald et al published 2007 in BMC Psychiatry

Estimation after blinded sample size reassessment

artículo científico publicado en 2016

Estimation in flexible two stage designs

article

Evidence, eminence and extrapolation

artículo científico publicado en 2016

Factors associated with success of market authorisation applications for pharmaceutical drugs submitted to the European Medicines Agency

article

Fixation of femoral fractures in multiple-injury patients with combined chest and head injuries

artículo científico publicado en 2003

Functional recovery at a minimum of 2 years after multiple injury-development of an outcome score

artículo científico publicado en 2008

Geriatric polytrauma

artículo científico publicado en 2005

Health-related quality of life of long-term survivors of intensive care: changes after intensive care treatment. Experience of an Austrian intensive care unit

artículo científico publicado en 2012

IFN-gamma-enhanced allergen penetration across respiratory epithelium augments allergic inflammation

artículo científico publicado en 2005

Immunohistochemical expression of matrix metalloproteinases 1 and 2 (MMP-1 and MMP-2) and tissue inhibitor of metalloproteinase 2 (TIMP-2) in ruptured and non-ruptured tubal ectopic pregnancies

artículo científico publicado en 2000

Innovative Approaches for Designing and Analyzing Adaptive Dose-Ranging Trials

Interim analysis incorporating short- and long-term binary endpoints

scientific article published on 29 January 2019

Joint EMA, ISBS, and DR-IBS International Symposium on Biopharmaceutical Statistics: bridging drug development from research to marketing.

artículo científico publicado en 2013

Lessons learned from IDeAl - 33 recommendations from the IDeAl-net about design and analysis of small population clinical trials.

artículo científico publicado en 2018

Lithium in the public water supply and suicide mortality in Texas

artículo científico publicado en 2013

Long-term outcome of belatacept therapy in de novo kidney transplant recipients - a case-match analysis

article

MCP2007 - 5th International Conference on Multiple Comparison Procedures

article

Many-to-one comparisons after safety selection in multi-arm clinical trials

artículo científico publicado en 2017

Marketing authorisation of orphan medicines in Europe from 2000 to 2013.

artículo científico publicado en 2017

Maximum type 1 error rate inflation in multiarmed clinical trials with adaptive interim sample size modifications

artículo científico publicado en 2014

Modified solid-phase alloantibody detection for improved crossmatch prediction.

artículo científico publicado en 2012

Multiplicity and flexibility in clinical trials.

artículo científico publicado en 2007

Nested combination tests with a time-to-event endpoint using a short-term endpoint for design adaptations

artículo científico publicado en 2019

One-year evaluation of two hybrid composites placed in a randomized-controlled clinical trial.

artículo científico publicado en 2014

Optimal choice of the number of treatments to be included in a clinical trial

artículo científico publicado en 2009

Optimized adaptive enrichment designs

artículo científico publicado en 2017

Optimizing Trial Designs for Targeted Therapies ⬇️

artículo científico publicado en 2016

Osteopontin expression predicts overall survival after liver transplantation for hepatocellular carcinoma in patients beyond the Milan criteria

artículo científico publicado en 2010

Polytrauma and air rescue. A retrospective analysis of trauma care in eastern Austria exemplified by an urban trauma center

artículo científico publicado en 2005

Psychosocial characteristics of victims of suicide in prisons

artículo científico publicado en 2002

Publisher Correction: Assessing mechanical catheter dysfunction in automated tidal peritoneal dialysis using cycler software: a case control, proof-of-concept study

artículo científico publicado en 2022

Quantitative analysis of factors affecting intraoperative precision and stability of optoelectronic and electromagnetic tracking systems

artículo científico publicado en 2002

Reading performance depending on the type of cataract and its predictability on the visual outcome

Rejoinder

Relative efficacy of drugs: an emerging issue between regulatory agencies and third-party payers

scientific article published on 26 February 2010

Reliability of a standardized reading chart system: variance component analysis, test-retest and inter-chart reliability.

artículo científico publicado en 2003

Response to comments on Jaki et al., A proposal for a new PhD level curriculum on quantitative methods for drug development. Pharm Stat 17(5):593-606, Sep/Oct 2018., DOI: https://doi.org/10.1002/pst.1873

artículo científico publicado en 2019

Role of modeling and simulation in pediatric investigation plans

artículo científico publicado en 2011

Sample Size Reassessment and Hypothesis Testing in Adaptive Survival Trials

artículo científico publicado en 2016

Sample Size for Multiple Hypothesis Testing in Biosimilar Development

article

Selection and bias--two hostile brothers

artículo científico publicado en 2010

Sharing clinical trial data on patient level: opportunities and challenges

artículo científico publicado en 2015

Single-reviewer abstract screening missed 13 percent of relevant studies: a crowd-based, randomized controlled trial

artículo científico publicado en 2020

Subgroup identification in clinical trials via the predicted individual treatment effect

artículo científico publicado en 2018

Suicide in custody: case-control study

artículo científico publicado en 2004

Suicide prevention in correctional institutions: The significance of solitary cell accommodation

Survival in patients undergoing transjugular intrahepatic portosystemic shunt: ePTFE-covered stentgrafts versus bare stents

artículo científico publicado en 2003

Testing and estimation in flexible group sequential designs with adaptive treatment selection

artículo científico publicado en 2005

The Distillation of “VISCI”: Towards a Better Identification of Suicidal Inmates

article published in 2009

The assessment of quality of life in a trial on lightweight mesh fixation with fibrin sealant in transabdominal preperitoneal hernia repair

artículo científico publicado en 2008

The fluorohydroxyapatite (FHA) FRIOSR AlgiporeR is a suitable biomaterial for the reconstruction of severely atrophic human maxillae

artículo científico publicado en 2003

The impact of colony-stimulating factor-1 on fracture healing: An experimental study

The reassessment of trial perspectives from interim data--a critical view

artículo científico publicado en 2006

The risks of methodology aversion in drug regulation

artículo científico publicado en 2014

The scientific work of Peter Bauer

artículo científico publicado en 2007

Transjugular intrahepatic portosystemic shunt in Vienna – A decade later

artículo científico publicado en 2004

Twenty-five years of confirmatory adaptive designs: opportunities and pitfalls.

artículo científico

VISCI--Viennese Instrument for Suicidality in Correctional Institutions

artículo científico publicado en 2007

Vascular endothelial growth factor (VEGF) and discrimination between abnormal intrauterine and ectopic pregnancy

artículo científico publicado en 2002

Lista de obras de Franz König

"Threshold-crossing": A Useful Way to Establish the Counterfactual in Clinical Trials?

A critical review of graphics for subgroup analyses in clinical trials

A double-blind, randomized, placebo-controlled trial of intravenous L-ornithine-L-aspartate on postural control in patients with cirrhosis

A multiple comparison procedure for dose-finding trials with subpopulations

A proposal for a new PhD level curriculum on quantitative methods for drug development.

A randomized controlled trial of alanyl-glutamine supplementation in peritoneal dialysis fluid to assess impact on biomarkers of peritoneal health

ABO antibody and complement depletion by immunoadsorption combined with membrane filtration--a randomized, controlled, cross-over trial

Adaptive Dunnett tests for treatment selection

Adaptive clinical trial designs for European marketing authorization: a survey of scientific advice letters from the European Medicines Agency

Adaptive designs for confirmatory clinical trials

Adaptive designs for subpopulation analysis optimizing utility functions

Adaptive graph-based multiple testing procedures

Adaptive paediatric investigation plans, a small step to improve regulatory decision making in drug development for children?

Aetiology of cirrhosis of the liver has an impact on survival predicted by the Model of End-stage Liver Disease score

Allergen-specific nasal IgG antibodies induced by vaccination with genetically modified allergens are associated with reduced nasal allergen sensitivity

An Adaptive Hierarchical Test Procedure for Selecting Safe and Efficient Treatments

An integrated MELD model including serum sodium and age improves the prediction of early mortality in patients with cirrhosis.

Authors' response to comments

Bcl-2 expression as a novel immunohistochemical marker for ruptured tubal ectopic pregnancy

Clearance of Selected Plasma Cytokines with Continuous Veno-Venous Hemodialysis Using Ultraflux EMiC2 versus Ultraflux AV1000S.

Clinical trials for authorized biosimilars in the European Union: a systematic review

Combination of anorganic bovine-derived hydroxyapatite with binding peptide does not enhance bone healing in a critical-size defect in a rabbit model

Commentary: Two approaches to analyze platform trials incorporating non-concurrent controls with a common assumption

Conditional Rejection Probabilities of Student'st-test and Design Adaptations

Confirmatory seamless phase II/III clinical trials with hypotheses selection at interim: general concepts

Cytotoxic effects of dental bonding substances as a function of degree of conversion

Cytotoxic effects of packable and nonpackable dental composites

Cytotoxic effects of veneer composite materials.

Cytotoxicity and shear bond strength of four orthodontic adhesive systems

Cytotoxicity of a calcium aluminate cement in comparison with other dental cements and resin-based materials

Cytotoxicity of four categories of dental cements.

Cytotoxicity of resin composites as a function of interface area

Degeneration and Instability and the Relation to Patients' Function Late After Lumbar Disc Surgery: Data from a 12-Year Follow-Up

Delayed treatment effects, treatment switching and heterogeneous patient populations: How to design and analyze RCTs in oncology

Deprivation versus importation: a model explaining the increase of suicide rates in custody

Development process of a consensus-driven CONSORT extension for randomised trials using an adaptive design

Diagnostic Contribution of Donor-Specific Antibody Characteristics to Uncover Late Silent Antibody-Mediated Rejection-Results of a Cross-Sectional Screening Study.

Do monthly or seasonal variations exist in suicides in a high-risk setting?

Effect of information on reported adverse events in a placebo-controlled trial

Effects of a Femoral Shaft Fracture on Multiply Injured Patients with a Head Injury

Epidemiology of jail and prison suicides in Austria

Estimation after blinded sample size reassessment

Estimation in flexible two stage designs

Evidence, eminence and extrapolation

Factors associated with success of market authorisation applications for pharmaceutical drugs submitted to the European Medicines Agency

Fixation of femoral fractures in multiple-injury patients with combined chest and head injuries

Functional recovery at a minimum of 2 years after multiple injury-development of an outcome score

Geriatric polytrauma

Health-related quality of life of long-term survivors of intensive care: changes after intensive care treatment. Experience of an Austrian intensive care unit

IFN-gamma-enhanced allergen penetration across respiratory epithelium augments allergic inflammation

Immunohistochemical expression of matrix metalloproteinases 1 and 2 (MMP-1 and MMP-2) and tissue inhibitor of metalloproteinase 2 (TIMP-2) in ruptured and non-ruptured tubal ectopic pregnancies

Innovative Approaches for Designing and Analyzing Adaptive Dose-Ranging Trials

Interim analysis incorporating short- and long-term binary endpoints

Joint EMA, ISBS, and DR-IBS International Symposium on Biopharmaceutical Statistics: bridging drug development from research to marketing.

Lessons learned from IDeAl - 33 recommendations from the IDeAl-net about design and analysis of small population clinical trials.

Lithium in the public water supply and suicide mortality in Texas

Long-term outcome of belatacept therapy in de novo kidney transplant recipients - a case-match analysis

MCP2007 - 5th International Conference on Multiple Comparison Procedures

Many-to-one comparisons after safety selection in multi-arm clinical trials

Marketing authorisation of orphan medicines in Europe from 2000 to 2013.

Maximum type 1 error rate inflation in multiarmed clinical trials with adaptive interim sample size modifications

Modified solid-phase alloantibody detection for improved crossmatch prediction.

Multiplicity and flexibility in clinical trials.

Nested combination tests with a time-to-event endpoint using a short-term endpoint for design adaptations

One-year evaluation of two hybrid composites placed in a randomized-controlled clinical trial.

Optimal choice of the number of treatments to be included in a clinical trial

Optimized adaptive enrichment designs

Optimizing Trial Designs for Targeted Therapies ⬇️

Osteopontin expression predicts overall survival after liver transplantation for hepatocellular carcinoma in patients beyond the Milan criteria

Polytrauma and air rescue. A retrospective analysis of trauma care in eastern Austria exemplified by an urban trauma center

Psychosocial characteristics of victims of suicide in prisons

Publisher Correction: Assessing mechanical catheter dysfunction in automated tidal peritoneal dialysis using cycler software: a case control, proof-of-concept study

Quantitative analysis of factors affecting intraoperative precision and stability of optoelectronic and electromagnetic tracking systems

Reading performance depending on the type of cataract and its predictability on the visual outcome

Rejoinder

Rejoinder

Relative efficacy of drugs: an emerging issue between regulatory agencies and third-party payers

Reliability of a standardized reading chart system: variance component analysis, test-retest and inter-chart reliability.

Response to comments on Jaki et al., A proposal for a new PhD level curriculum on quantitative methods for drug development. Pharm Stat 17(5):593-606, Sep/Oct 2018., DOI: https://doi.org/10.1002/pst.1873