Lista de obras - Paul Nghiem - Dominio Público Uruguay

31st Annual Meeting and Associated Programs of the Society for Immunotherapy of Cancer (SITC 2016): part one

artículo científico publicado en 2016

A new American Joint Committee on Cancer staging system for cutaneous squamous cell carcinoma: creation and rationale for inclusion of tumor (T) characteristics.

artículo científico publicado en 2011

ATR Regulates Fragile Site Stability

artículo científico publicado en 2002

ATR inhibition selectively sensitizes G1 checkpoint-deficient cells to lethal premature chromatin condensation

artículo científico publicado en 2001

ATR is not required for p53 activation but synergizes with p53 in the replication checkpoint

artículo científico publicado en 2001

Acquired cancer resistance to combination immunotherapy from transcriptional loss of class I HLA

scientific article published in Nature Communications

Activation of the ATR-mediated DNA damage response by the HIV-1 viral protein R.

artículo científico publicado en 2003

Antibodies to Merkel Cell Polyomavirus T Antigen Oncoproteins Reflect Tumor Burden in Merkel Cell Carcinoma Patients ⬇️

artículo científico publicado el 19 de octubre de 2010

Antisense oligodeoxynucleotides to the cystic fibrosis transmembrane conductance regulator inhibit cAMP-activated but not calcium-activated chloride currents ⬇️

artículo científico publicado el 1 de agosto de 1992

Asymmetric lateral distribution of melanoma and Merkel cell carcinoma in the United States.

artículo científico publicado en 2011

Basal cell and squamous cell skin cancers

artículo científico publicado en 2010

Basal cell and squamous cell skin cancers

artículo científico publicado en 2007

CD200 Expression in Neuroendocrine Neoplasms

artículo científico publicado en 2017

Caffeine decreases phospho-Chk1 (Ser317) and increases mitotic cells with cyclin B1 and caspase 3 in tumors from UVB-treated mice

artículo científico publicado en 2011

Case 19-2008: Merkel-cell carcinoma

artículo científico publicado en 2008

Chemical genetics: elucidating biological systems with small-molecule compounds

artículo científico publicado en 2007

Chemical methodology as a source of small-molecule checkpoint inhibitors and heat shock protein 70 (Hsp70) modulators

artículo científico publicado en 2011

Circulating Cell-Free miR-375 as Surrogate Marker of Tumor Burden in Merkel Cell Carcinoma

scientific article published on 30 July 2018

Clinical characteristics of Merkel cell carcinoma at diagnosis in 195 patients: the AEIOU features.

artículo científico publicado en 2008

Clinical utility of a circulating tumor cell assay in Merkel cell carcinoma

artículo científico publicado en 2013

Dermatofibrosarcoma protuberans

scientific article published on 01 May 2007

Dermatofibrosarcoma protuberans

artículo científico publicado en 2012

Diagnostic biopsy does not commonly induce intratumoral CD8 T cell infiltration in Merkel cell carcinoma

artículo científico publicado en 2012

Effect of caffeine on the ATR/Chk1 pathway in the epidermis of UVB-irradiated mice.

artículo científico publicado en 2008

Emerging and mechanism-based therapies for recurrent or metastatic Merkel cell carcinoma

artículo científico

Epidemiology, biology and therapy of Merkel cell carcinoma: conclusions from the EU project IMMOMEC.

artículo científico publicado en 2017

Epigenetic priming restores the HLA class-I antigen processing machinery expression in Merkel cell carcinoma

artículo científico publicado en 2017

Human CD4+ T Cells Specific for Merkel Cell Polyomavirus Localize to Merkel Cell Carcinomas and Target a Required Oncogenic Domain

scientific article published on 12 August 2019

Human immunodeficiency virus type 1 Vpr-mediated G2 arrest requires Rad17 and Hus1 and induces nuclear BRCA1 and gamma-H2AX focus formation.

artículo científico publicado en 2004

Identification and validation of a novel mature microRNA encoded by the Merkel cell polyomavirus in human Merkel cell carcinomas

artículo científico publicado en 2011

Identification of Therapeutic Vulnerabilities in Small-cell Neuroendocrine Prostate Cancer

scientific article published on 05 December 2019

Immune evasion mechanisms and immune checkpoint inhibition in advanced merkel cell carcinoma

artículo científico publicado en 2017

Immunobiology of Merkel cell carcinoma: implications for immunotherapy of a polyomavirus-associated cancer.

artículo científico publicado en 2011

Importance of genetic studies in patients with multiple merkel cell carcinomas

artículo científico publicado en 2012

Inhibition of UVB-induced nonmelanoma skin cancer: a path from tea to caffeine to exercise to decreased tissue fat

artículo científico publicado en 2013

Interleukin-2 transcriptional block by multifunctional Ca2+/calmodulin kinase

artículo científico publicado en 1994

Intratumoral Delivery of Plasmid IL12 Via Electroporation Leads to Regression of Injected and Noninjected Tumors in Merkel Cell Carcinoma

scientific article published on 03 October 2019

Intratumoral G100, a TLR4 Agonist, Induces Antitumor Immune Responses and Tumor Regression in Patients with Merkel Cell Carcinoma

artículo científico publicado en 2018

Left-sided skin cancers on the arm from driving? Past and future lessons from Australia

artículo científico publicado en 2011

Mechanisms of Caffeine-Induced Inhibition of UVB Carcinogenesis ⬇️

artículo científico publicado el 17 de junio de 2013

Merkel cell carcinoma

artículo científico publicado en 2006

Merkel cell carcinoma

artículo científico publicado en 2009

Merkel cell carcinoma adjuvant therapy: current data support radiation but not chemotherapy

artículo científico publicado en 2007

Merkel cell carcinoma associated with HIV: review of 14 patients.

artículo científico publicado en 2011

Merkel cell carcinoma in the age of immunotherapy: Facts and hopes

artículo científico publicado en 2017

Merkel cell carcinoma patients presenting without a primary lesion have elevated markers of immunity, higher tumor mutation burden and improved survival.

artículo científico publicado en 2017

Merkel cell carcinoma treatment with radiation: a good case despite no prospective studies

artículo científico publicado en 2003

Merkel cell carcinoma: Current US incidence and projected increases based on changing demographics

artículo científico publicado en 2017

Merkel cell carcinoma: if no breslow, then what?

scientific article published on 01 June 2007

Merkel cell carcinoma: more deaths but still no pathway to blame

artículo científico publicado en 2007

Merkel cell polyomavirus is more frequently present in North American than Australian Merkel cell carcinoma tumors.

artículo científico publicado en 2008

Merkel cell polyomavirus is not detected in prostate cancers, surrounding stroma, or benign prostate controls

artículo científico publicado en 2009

Merkel cell polyomavirus large T antigen has growth-promoting and inhibitory activities

artículo científico publicado en 2013

Merkel cell polyomavirus-specific CD8⁺ and CD4⁺ T-cell responses identified in Merkel cell carcinomas and blood.

artículo científico publicado en 2011

Merkel cell polyomavirus-specific immune responses in patients with Merkel cell carcinoma receiving anti-PD-1 therapy

article

Merkel polyomavirus-specific T cells fluctuate with merkel cell carcinoma burden and express therapeutically targetable PD-1 and Tim-3 exhaustion markers

artículo científico publicado en 2013

Osteopontin is linked with AKT, FoxO1, and myostatin in skeletal muscle cells.

artículo científico publicado en 2017

PD-1 Blockade with Pembrolizumab in Advanced Merkel-Cell Carcinoma.

artículo científico publicado en 2016

Paraneoplastic syndromes (PNS) associated with Merkel cell carcinoma (MCC): A case series of 8 patients highlighting different clinical manifestations

artículo científico publicado en 2016

Pathologic nodal evaluation is increasingly commonly performed for patients with Merkel cell carcinoma.

scientific article published on October 2013

Patterns of distant metastases in 215 Merkel cell carcinoma patients: Implications for prognosis and surveillance

artículo científico publicado en 2019

Polyomavirus-driven Merkel cell carcinoma: Prospects for therapeutic vaccine development

artículo científico publicado en 2020

Prevalent and diverse intratumoral oncoprotein-specific CD8+ T cells within polyoma virus-driven Merkel cell carcinomas

artículo científico publicado en 2020

Prostaglandin E 1 activates a chloride current in Jurkat T lymphocytes via cAMP‐dependent protein kinase ⬇️

artículo científico publicado el 1 de noviembre de 1991

Protection from UV-induced skin carcinogenesis by genetic inhibition of the ataxia telangiectasia and Rad3-related (ATR) kinase ⬇️

artículo científico publicado el 15 de agosto de 2011

Protection from photodamage by topical application of caffeine after ultraviolet irradiation

artículo científico publicado en 2007

Protocol for the examination of specimens from patients with merkel cell carcinoma of the skin

artículo científico publicado en 2010

Radiation monotherapy as regional treatment for lymph node-positive Merkel cell carcinoma

artículo científico publicado en 2010

Regression of metastatic Merkel cell carcinoma following transfer of polyomavirus-specific T cells and therapies capable of re-inducing HLA class-I

artículo científico publicado en 2014

Role of skin biopsy to confirm suspected acute graft-vs-host disease: results of decision analysis

artículo científico publicado en 2006

Surgical removal of the parametrial fat pads stimulates apoptosis and inhibits UVB-induced carcinogenesis in mice fed a high-fat diet

artículo científico publicado en 2012

Systemic Immune Suppression Predicts Diminished Merkel Cell Carcinoma–Specific Survival Independent of Stage ⬇️

artículo científico publicado el 29 de noviembre de 2012

Targeting Merkel cell carcinoma by engineered T cells specific to T-antigens of Merkel cell polyomavirus

artículo científico publicado en 2018

The "drug vs graft-vs-host disease" conundrum gets tougher, but there is an answer: the challenge to dermatologists

artículo científico publicado en 2001

The 6-4 photoproduct is the trigger of UV-induced replication blockage and ATR activation

artículo científico publicado en 2020

The Protective Role of a Small GTPase RhoE against UVB-induced DNA Damage in Keratinocytes

scientific article published on 14 December 2006

The standard of care for Merkel cell carcinoma should include adjuvant radiation and lymph node surgery

scientific article published on 01 April 2002

Transcriptome-wide studies of merkel cell carcinoma and validation of intratumoral CD8+ lymphocyte invasion as an independent predictor of survival.

artículo científico publicado en 2011

Tuberculosis following PD-1 blockade for cancer immunotherapy

scientific article published on 01 January 2019

Tumor-specific T cells in human Merkel cell carcinomas: a possible role for Tregs and T-cell exhaustion in reducing T-cell responses.

artículo científico publicado en 2013

Updated efficacy of avelumab in patients with previously treated metastatic Merkel cell carcinoma after ≥1 year of follow-up: JAVELIN Merkel 200, a phase 2 clinical trial

artículo científico publicado en 2018

p63 Expression in Merkel Cell Carcinoma Predicts Poorer Survival yet May Have Limited Clinical Utility

artículo científico publicado en 2013

Lista de obras de Paul Nghiem

31st Annual Meeting and Associated Programs of the Society for Immunotherapy of Cancer (SITC 2016): part one

A new American Joint Committee on Cancer staging system for cutaneous squamous cell carcinoma: creation and rationale for inclusion of tumor (T) characteristics.

ATR Regulates Fragile Site Stability

ATR inhibition selectively sensitizes G1 checkpoint-deficient cells to lethal premature chromatin condensation

ATR is not required for p53 activation but synergizes with p53 in the replication checkpoint

Acquired cancer resistance to combination immunotherapy from transcriptional loss of class I HLA

Activation of the ATR-mediated DNA damage response by the HIV-1 viral protein R.

Antibodies to Merkel Cell Polyomavirus T Antigen Oncoproteins Reflect Tumor Burden in Merkel Cell Carcinoma Patients ⬇️

Antisense oligodeoxynucleotides to the cystic fibrosis transmembrane conductance regulator inhibit cAMP-activated but not calcium-activated chloride currents ⬇️

Asymmetric lateral distribution of melanoma and Merkel cell carcinoma in the United States.

Basal cell and squamous cell skin cancers

Basal cell and squamous cell skin cancers

CD200 Expression in Neuroendocrine Neoplasms

Caffeine decreases phospho-Chk1 (Ser317) and increases mitotic cells with cyclin B1 and caspase 3 in tumors from UVB-treated mice

Case 19-2008: Merkel-cell carcinoma

Chemical genetics: elucidating biological systems with small-molecule compounds

Chemical methodology as a source of small-molecule checkpoint inhibitors and heat shock protein 70 (Hsp70) modulators

Circulating Cell-Free miR-375 as Surrogate Marker of Tumor Burden in Merkel Cell Carcinoma

Clinical characteristics of Merkel cell carcinoma at diagnosis in 195 patients: the AEIOU features.

Clinical utility of a circulating tumor cell assay in Merkel cell carcinoma

Dermatofibrosarcoma protuberans

Dermatofibrosarcoma protuberans

Diagnostic biopsy does not commonly induce intratumoral CD8 T cell infiltration in Merkel cell carcinoma

Effect of caffeine on the ATR/Chk1 pathway in the epidermis of UVB-irradiated mice.

Emerging and mechanism-based therapies for recurrent or metastatic Merkel cell carcinoma

Epidemiology, biology and therapy of Merkel cell carcinoma: conclusions from the EU project IMMOMEC.

Epigenetic priming restores the HLA class-I antigen processing machinery expression in Merkel cell carcinoma

Human CD4+ T Cells Specific for Merkel Cell Polyomavirus Localize to Merkel Cell Carcinomas and Target a Required Oncogenic Domain

Human immunodeficiency virus type 1 Vpr-mediated G2 arrest requires Rad17 and Hus1 and induces nuclear BRCA1 and gamma-H2AX focus formation.

Identification and validation of a novel mature microRNA encoded by the Merkel cell polyomavirus in human Merkel cell carcinomas

Identification of Therapeutic Vulnerabilities in Small-cell Neuroendocrine Prostate Cancer

Immune evasion mechanisms and immune checkpoint inhibition in advanced merkel cell carcinoma

Immunobiology of Merkel cell carcinoma: implications for immunotherapy of a polyomavirus-associated cancer.

Importance of genetic studies in patients with multiple merkel cell carcinomas

Inhibition of UVB-induced nonmelanoma skin cancer: a path from tea to caffeine to exercise to decreased tissue fat

Interleukin-2 transcriptional block by multifunctional Ca2+/calmodulin kinase

Intratumoral Delivery of Plasmid IL12 Via Electroporation Leads to Regression of Injected and Noninjected Tumors in Merkel Cell Carcinoma

Intratumoral G100, a TLR4 Agonist, Induces Antitumor Immune Responses and Tumor Regression in Patients with Merkel Cell Carcinoma

Left-sided skin cancers on the arm from driving? Past and future lessons from Australia

Mechanisms of Caffeine-Induced Inhibition of UVB Carcinogenesis ⬇️

Merkel cell carcinoma

Merkel cell carcinoma

Merkel cell carcinoma adjuvant therapy: current data support radiation but not chemotherapy

Merkel cell carcinoma associated with HIV: review of 14 patients.

Merkel cell carcinoma in the age of immunotherapy: Facts and hopes

Merkel cell carcinoma patients presenting without a primary lesion have elevated markers of immunity, higher tumor mutation burden and improved survival.

Merkel cell carcinoma treatment with radiation: a good case despite no prospective studies

Merkel cell carcinoma: Current US incidence and projected increases based on changing demographics

Merkel cell carcinoma: if no breslow, then what?

Merkel cell carcinoma: more deaths but still no pathway to blame

Merkel cell polyomavirus is more frequently present in North American than Australian Merkel cell carcinoma tumors.

Merkel cell polyomavirus is not detected in prostate cancers, surrounding stroma, or benign prostate controls

Merkel cell polyomavirus large T antigen has growth-promoting and inhibitory activities

Merkel cell polyomavirus-specific CD8⁺ and CD4⁺ T-cell responses identified in Merkel cell carcinomas and blood.

Merkel cell polyomavirus-specific immune responses in patients with Merkel cell carcinoma receiving anti-PD-1 therapy

Merkel polyomavirus-specific T cells fluctuate with merkel cell carcinoma burden and express therapeutically targetable PD-1 and Tim-3 exhaustion markers

Osteopontin is linked with AKT, FoxO1, and myostatin in skeletal muscle cells.

PD-1 Blockade with Pembrolizumab in Advanced Merkel-Cell Carcinoma.

Paraneoplastic syndromes (PNS) associated with Merkel cell carcinoma (MCC): A case series of 8 patients highlighting different clinical manifestations

Pathologic nodal evaluation is increasingly commonly performed for patients with Merkel cell carcinoma.

Patterns of distant metastases in 215 Merkel cell carcinoma patients: Implications for prognosis and surveillance

Polyomavirus-driven Merkel cell carcinoma: Prospects for therapeutic vaccine development

Prevalent and diverse intratumoral oncoprotein-specific CD8+ T cells within polyoma virus-driven Merkel cell carcinomas

Prostaglandin E 1 activates a chloride current in Jurkat T lymphocytes via cAMP‐dependent protein kinase ⬇️

Protection from UV-induced skin carcinogenesis by genetic inhibition of the ataxia telangiectasia and Rad3-related (ATR) kinase ⬇️

Protection from photodamage by topical application of caffeine after ultraviolet irradiation

Protocol for the examination of specimens from patients with merkel cell carcinoma of the skin

Radiation monotherapy as regional treatment for lymph node-positive Merkel cell carcinoma

Regression of metastatic Merkel cell carcinoma following transfer of polyomavirus-specific T cells and therapies capable of re-inducing HLA class-I

Role of skin biopsy to confirm suspected acute graft-vs-host disease: results of decision analysis

Surgical removal of the parametrial fat pads stimulates apoptosis and inhibits UVB-induced carcinogenesis in mice fed a high-fat diet

Systemic Immune Suppression Predicts Diminished Merkel Cell Carcinoma–Specific Survival Independent of Stage ⬇️

Targeting Merkel cell carcinoma by engineered T cells specific to T-antigens of Merkel cell polyomavirus

The "drug vs graft-vs-host disease" conundrum gets tougher, but there is an answer: the challenge to dermatologists

The 6-4 photoproduct is the trigger of UV-induced replication blockage and ATR activation

The Protective Role of a Small GTPase RhoE against UVB-induced DNA Damage in Keratinocytes

The standard of care for Merkel cell carcinoma should include adjuvant radiation and lymph node surgery

Transcriptome-wide studies of merkel cell carcinoma and validation of intratumoral CD8+ lymphocyte invasion as an independent predictor of survival.

Tuberculosis following PD-1 blockade for cancer immunotherapy