Lista de obras - Thomas L Saunders - Dominio Público Uruguay

A Survey of Internet Resources for Mouse Development

artículo científico publicado el 1 de enero de 2010

A knockin mouse model of spinocerebellar ataxia type 3 exhibits prominent aggregate pathology and aberrant splicing of the disease gene transcript

artículo científico publicado en 2017

A knockin mouse model of spinocerebellar ataxia type 3 exhibits prominent aggregate pathology and aberrant splicing of the disease gene transcript.

artículo científico publicado en 2014

A novel intergenic ETnII-β insertion mutation causes multiple malformations in polypodia mice

artículo científico publicado en 2013

A rheumatoid factor transgenic mouse model of autoantibody regulation

artículo científico publicado en 1993

A simple qPCR-based method to detect correct insertion of homologous targeting vectors in murine ES cells.

artículo científico publicado en 2007

A transient transgenic RNAi strategy for rapid characterization of gene function during embryonic development

artículo científico publicado en 2010

Absence of complement component 3 does not prevent classical pathway-mediated hemolysis

artículo científico publicado en 2019

Activator of G protein signaling 3 null mice: I. Unexpected alterations in metabolic and cardiovascular function

artículo científico publicado en 2008

Advances in transgenic rat production

artículo científico publicado en 2006

Altered podocyte structure in GLEPP1 (Ptpro)-deficient mice associated with hypertension and low glomerular filtration rate

scientific journal article

An inactivating caspase 11 passenger mutation originating from the 129 murine strain in mice targeted for c-IAP1

artículo científico publicado en 2012

An upstream enhancer regulates Gpihbp1 expression in a tissue-specific manner

scientific article published on 31 December 2018

Beta-mannosidosis mice: a model for the human lysosomal storage disease

artículo científico publicado en 2005

Blood vascular abnormalities in Rasa1(R780Q) knockin mice: implications for the pathogenesis of capillary malformation-arteriovenous malformation

artículo científico publicado en 2014

Claudin 14 knockout mice, a model for autosomal recessive deafness DFNB29, are deaf due to cochlear hair cell degeneration

artículo científico publicado en 2003

Correction of deafness in shaker-2 mice by an unconventional myosin in a BAC transgene.

artículo científico publicado en 1998

Cutting Edge: IFN-γ Produced by Brain-Resident Cells Is Crucial To Control Cerebral Infection with Toxoplasma gondii

artículo científico publicado en 2015

Deficiency of Reproductive Tract α(1,2)Fucosylated Glycans and Normal Fertility in Mice with Targeted Deletions of the FUT1 or FUT2 α(1,2)Fucosyltransferase Locus ⬇️

artículo científico publicado el 1 de diciembre de 2001

Dentin sialophosphoprotein: a regulatory protein for dental pulp stem cell identity and fate

artículo científico publicado en 2014

Distant regulatory elements in a Sox10-beta GEO BAC transgene are required for expression of Sox10 in the enteric nervous system and other neural crest-derived tissues.

artículo científico publicado en 2006

Efficient, specific, developmentally appropriate cre-mediated recombination in anterior pituitary gonadotropes and thyrotropes.

artículo científico publicado en 2013

Endoplasmic reticulum stress activates cleavage of CREBH to induce a systemic inflammatory response

artículo científico publicado en 2006

Endothelial and perivascular cells maintain haematopoietic stem cells

artículo científico publicado en 2012

Fidelity of a BAC-EGFP transgene in reporting dynamic expression of IL-7Rα in T cells.

artículo científico publicado en 2011

Full-length DQ beta cDNA sequences of HLA-DR2/DQw1 subtypes: genetic interactions between two DQ beta loci generate human class II HLA diversity.

artículo científico publicado en 1990

Functional roles of MMP14 and MMP15 in early postnatal mammary gland development.

artículo científico publicado en 2016

Functions of the COPII gene paralogs SEC23A and SEC23B are interchangeable in vivo

artículo científico publicado en 2018

Generating transgenic mice from bacterial artificial chromosomes: transgenesis efficiency, integration and expression outcomes.

artículo científico publicado en 2009

Generation of Amelx-iCre Mice Supports Ameloblast-Specific Role for Stim1

scientific article published on 01 August 2019

Generation of mice with a conditional allele of the p120 Ras GTPase-activating protein.

artículo científico publicado en 2007

Genetic analysis of SH2D4A, a novel adapter protein related to T cell-specific adapter and adapter protein in lymphocytes of unknown function, reveals a redundant function in T cells

artículo científico publicado en 2008

Genetic analysis of the neuronal and ubiquitous AP-3 adaptor complexes reveals divergent functions in brain.

artículo científico publicado en 2004

Genetic variation in C57BL/6 ES cell lines and genetic instability in the Bruce4 C57BL/6 ES cell line

artículo científico publicado en 2007

Glucose transporter-1-deficient mice exhibit impaired development and deformities that are similar to diabetic embryopathy.

artículo científico publicado en 2003

Hair Cell Loss, Spiral Ganglion Degeneration, and Progressive Sensorineural Hearing Loss in Mice with Targeted Deletion of Slc44a2/Ctl2.

artículo científico publicado en 2015

Highly efficient CRISPR/HDR-mediated knock-in for mouse embryonic stem cells and zygotes.

artículo científico publicado en 2015

In vivo glucoregulation and tissue-specific glucose uptake in female Akt substrate 160 kDa knockout rats

artículo científico publicado en 2020

Inducible Transgenic Mouse Models ⬇️

artículo científico publicado el 1 de enero de 2011

Isolating Bacterial Artificial Chromosome (BAC) DNA from Bacterial Cultures Using the NucleoBond System

artículo científico publicado el 1 de junio de 2006

Knock-In Rat Lines with Cre Recombinase at the Dopamine D1 and Adenosine 2a Receptor Loci

scientific article published on 01 September 2019

Lgi4 promotes the proliferation and differentiation of glial lineage cells throughout the developing peripheral nervous system

scientific journal article

Lkb1 regulates cell cycle and energy metabolism in haematopoietic stem cells

artículo científico publicado en 2010

Loss of Omi mitochondrial protease activity causes the neuromuscular disorder of mnd2 mutant mice

artículo científico publicado en 2003

MT1-MMP-dependent control of skeletal stem cell commitment via a β1-integrin/YAP/TAZ signaling axis.

scientific article published on 16 May 2013

Mature T cell responses are controlled by microRNA-142.

artículo científico publicado en 2015

Merkel Cell Polyomavirus Small T Antigen Initiates Merkel Cell Carcinoma-like Tumor Development in Mice

artículo científico publicado en 2017

Merkel cell polyomavirus small T antigen is oncogenic in transgenic mice.

artículo científico publicado en 2014

Mesenchymal cells reactivate Snail1 expression to drive three-dimensional invasion programs

artículo científico publicado en 2009

Mice hypomorphic for Atr have increased DNA damage and abnormal checkpoint response.

artículo científico publicado en 2009

Mice lacking sodium channel beta1 subunits display defects in neuronal excitability, sodium channel expression, and nodal architecture

scientific journal article

Mouse model of enlarged vestibular aqueducts defines temporal requirement of Slc26a4 expression for hearing acquisition

artículo científico publicado en 2011

Murine Surf4 is essential for early embryonic development

scientific article published on 24 January 2020

Mutations in RELT cause autosomal recessive amelogenesis imperfecta

Noncoding Microdeletion in Mouse Hgf Disrupts Neural Crest Migration into the Stria Vascularis, Reduces the Endocochlear Potential, and Suggests the Neuropathology for Human Nonsyndromic Deafness DFNB39

scientific article published on 09 March 2020

Normal TCR signal transduction in mice that lack catalytically active PTPN3 protein tyrosine phosphatase

scientific article published on 01 March 2007

Notch pathway targets proangiogenic regulator Sox17 to restrict angiogenesis

artículo científico publicado en 2014

Obesity-Induced Infertility in Male Mice Is Associated With Disruption of Crisp4 Expression and Sperm Fertilization Capacity.

artículo científico publicado en 2017

Pituitary hypoplasia and respiratory distress syndrome in Prop1 knockout mice

scientific journal article

Pituitary-specific Gata2 knockout: effects on gonadotrope and thyrotrope function

scientific journal article

Pleiotropic phenotype of a genomic knock-in of an RGS-insensitive G184S Gnai2 allele

artículo científico publicado en 2006

Podocyte depletion causes glomerulosclerosis: diphtheria toxin-induced podocyte depletion in rats expressing human diphtheria toxin receptor transgene

artículo científico publicado en 2005

Podocyte-specific JAK2 overexpression worsens diabetic kidney disease in mice.

artículo científico publicado en 2017

Podocyte-specific overexpression of GLUT1 surprisingly reduces mesangial matrix expansion in diabetic nephropathy in mice

artículo científico publicado en 2010

Principles of Genetic Engineering

scientific article published on 10 March 2020

Production of the butyrylcholinesterase knockout mouse.

artículo científico publicado en 2006

Purification of Bacterial Artificial Chromosome (BAC) DNA Prepared with the NucleoBond System

artículo científico publicado el 1 de junio de 2006

Purification of immunoprotective tumor antigens by preparative isotachophoresis.

artículo científico publicado en 1983

RNF8-dependent histone modifications regulate nucleosome removal during spermatogenesis

scientific journal article

Rederivation of transgenic and gene-targeted mice by embryo transfer.

artículo científico publicado en 2004

Reporter molecules in genetically engineered mice

scientific article published on 01 January 2003

Resistance to organophosphorus agent toxicity in transgenic mice expressing the G117H mutant of human butyrylcholinesterase.

artículo científico publicado en 2004

Ribosomal protein L24 defect in belly spot and tail (Bst), a mouse Minute

artículo científico publicado en 2004

Role of Complement in a Rat Model of Paclitaxel-Induced Peripheral Neuropathy

artículo científico publicado en 2018

SAG/RBX2/ROC2 E3 Ubiquitin Ligase Is Essential for Vascular and Neural Development by Targeting NF1 for Degradation ⬇️

artículo científico publicado el 23 de noviembre de 2011

SRA gene knockout protects against diet-induced obesity and improves glucose tolerance

artículo científico publicado en 2014

Secreted versus membrane-anchored collagenases: relative roles in fibroblast-dependent collagenolysis and invasion.

artículo científico publicado en 2009

Sensitized mutagenesis screen in Factor V Leiden mice identifies thrombosis suppressor loci.

artículo científico publicado en 2017

Sexually dimorphic distribution of Prokr2 neurons revealed by the Prokr2-Cre mouse model

artículo científico publicado en 2017

Sox17 dependence distinguishes the transcriptional regulation of fetal from adult hematopoietic stem cells

scientific journal article

Specific inhibition of mouse oocyte nuclear protein phosphatase-1 stimulates germinal vesicle breakdown

artículo científico publicado en 2003

Targeted ablation of pituitary gonadotropes in transgenic mice.

artículo científico publicado en 1991

Targeted disruption of Adamts16 gene in a rat genetic model of hypertension

scientific journal article

Targeted disruption of Cd40 in a genetically hypertensive rat model attenuates renal fibrosis and proteinuria, independent of blood pressure.

artículo científico publicado en 2016

Targeted disruption of the pituitary glycoprotein hormone alpha-subunit produces hypogonadal and hypothyroid mice.

artículo científico publicado en 1995

The Pit-1 transcription factor gene is a candidate for the murine Snell dwarf mutation

artículo científico publicado en 1990

The chemerin knockout rat reveals chemerin dependence in female, but not male, experimental hypertension

artículo científico publicado en 2018

The effect of repeated light-dark shifts on uterine receptivity and early gestation in mice undergoing embryo transfer

artículo científico publicado en 2017

The proximal promoter of the bovine luteinizing hormone beta-subunit gene confers gonadotrope-specific expression and regulation by gonadotropin-releasing hormone, testosterone, and 17 beta-estradiol in transgenic mice

article

The α(1,3)Fucosyltransferase Fuc-TVII Controls Leukocyte Trafficking through an Essential Role in L-, E-, and P-selectin Ligand Biosynthesis

scientific article published on 01 August 1996

Thioredoxin overexpression in both the cytosol and mitochondria accelerates age-related disease and shortens lifespan in male C57BL/6 mice

article

Tissue-specific expression of ferritin H regulates cellular iron homoeostasis in vivo

artículo científico publicado en 2006

Translational control is required for the unfolded protein response and in vivo glucose homeostasis

artículo científico publicado en 2001

Trap1a is an X-linked and cell-intrinsic regulator of thymocyte development.

artículo científico publicado en 2016

Two pathways for cyclooxygenase-2 protein degradation in vivo

artículo científico publicado en 2009

Vitronectin is not essential for normal mammalian development and fertility.

artículo científico publicado en 1995

Whole exome sequencing of ENU-induced thrombosis modifier mutations in the mouse

scientific article published on 06 September 2018

Lista de obras de Thomas L Saunders

A Survey of Internet Resources for Mouse Development

A knockin mouse model of spinocerebellar ataxia type 3 exhibits prominent aggregate pathology and aberrant splicing of the disease gene transcript

A knockin mouse model of spinocerebellar ataxia type 3 exhibits prominent aggregate pathology and aberrant splicing of the disease gene transcript.

A novel intergenic ETnII-β insertion mutation causes multiple malformations in polypodia mice

A rheumatoid factor transgenic mouse model of autoantibody regulation

A simple qPCR-based method to detect correct insertion of homologous targeting vectors in murine ES cells.

A transient transgenic RNAi strategy for rapid characterization of gene function during embryonic development

Absence of complement component 3 does not prevent classical pathway-mediated hemolysis

Activator of G protein signaling 3 null mice: I. Unexpected alterations in metabolic and cardiovascular function

Advances in transgenic rat production

Altered podocyte structure in GLEPP1 (Ptpro)-deficient mice associated with hypertension and low glomerular filtration rate

An inactivating caspase 11 passenger mutation originating from the 129 murine strain in mice targeted for c-IAP1

An upstream enhancer regulates Gpihbp1 expression in a tissue-specific manner

Beta-mannosidosis mice: a model for the human lysosomal storage disease

Blood vascular abnormalities in Rasa1(R780Q) knockin mice: implications for the pathogenesis of capillary malformation-arteriovenous malformation

Claudin 14 knockout mice, a model for autosomal recessive deafness DFNB29, are deaf due to cochlear hair cell degeneration

Correction of deafness in shaker-2 mice by an unconventional myosin in a BAC transgene.

Cutting Edge: IFN-γ Produced by Brain-Resident Cells Is Crucial To Control Cerebral Infection with Toxoplasma gondii

Deficiency of Reproductive Tract α(1,2)Fucosylated Glycans and Normal Fertility in Mice with Targeted Deletions of the FUT1 or FUT2 α(1,2)Fucosyltransferase Locus ⬇️

Dentin sialophosphoprotein: a regulatory protein for dental pulp stem cell identity and fate

Distant regulatory elements in a Sox10-beta GEO BAC transgene are required for expression of Sox10 in the enteric nervous system and other neural crest-derived tissues.

Efficient, specific, developmentally appropriate cre-mediated recombination in anterior pituitary gonadotropes and thyrotropes.

Endoplasmic reticulum stress activates cleavage of CREBH to induce a systemic inflammatory response

Endothelial and perivascular cells maintain haematopoietic stem cells

Fidelity of a BAC-EGFP transgene in reporting dynamic expression of IL-7Rα in T cells.

Full-length DQ beta cDNA sequences of HLA-DR2/DQw1 subtypes: genetic interactions between two DQ beta loci generate human class II HLA diversity.

Functional roles of MMP14 and MMP15 in early postnatal mammary gland development.

Functions of the COPII gene paralogs SEC23A and SEC23B are interchangeable in vivo

Generating transgenic mice from bacterial artificial chromosomes: transgenesis efficiency, integration and expression outcomes.

Generation of Amelx-iCre Mice Supports Ameloblast-Specific Role for Stim1

Generation of mice with a conditional allele of the p120 Ras GTPase-activating protein.

Genetic analysis of SH2D4A, a novel adapter protein related to T cell-specific adapter and adapter protein in lymphocytes of unknown function, reveals a redundant function in T cells

Genetic analysis of the neuronal and ubiquitous AP-3 adaptor complexes reveals divergent functions in brain.

Genetic variation in C57BL/6 ES cell lines and genetic instability in the Bruce4 C57BL/6 ES cell line

Glucose transporter-1-deficient mice exhibit impaired development and deformities that are similar to diabetic embryopathy.

Hair Cell Loss, Spiral Ganglion Degeneration, and Progressive Sensorineural Hearing Loss in Mice with Targeted Deletion of Slc44a2/Ctl2.

Highly efficient CRISPR/HDR-mediated knock-in for mouse embryonic stem cells and zygotes.

In vivo glucoregulation and tissue-specific glucose uptake in female Akt substrate 160 kDa knockout rats

Inducible Transgenic Mouse Models ⬇️

Isolating Bacterial Artificial Chromosome (BAC) DNA from Bacterial Cultures Using the NucleoBond System

Knock-In Rat Lines with Cre Recombinase at the Dopamine D1 and Adenosine 2a Receptor Loci

Lgi4 promotes the proliferation and differentiation of glial lineage cells throughout the developing peripheral nervous system

Lkb1 regulates cell cycle and energy metabolism in haematopoietic stem cells

Loss of Omi mitochondrial protease activity causes the neuromuscular disorder of mnd2 mutant mice

MT1-MMP-dependent control of skeletal stem cell commitment via a β1-integrin/YAP/TAZ signaling axis.

Mature T cell responses are controlled by microRNA-142.

Merkel Cell Polyomavirus Small T Antigen Initiates Merkel Cell Carcinoma-like Tumor Development in Mice

Merkel cell polyomavirus small T antigen is oncogenic in transgenic mice.

Mesenchymal cells reactivate Snail1 expression to drive three-dimensional invasion programs

Mice hypomorphic for Atr have increased DNA damage and abnormal checkpoint response.

Mice lacking sodium channel beta1 subunits display defects in neuronal excitability, sodium channel expression, and nodal architecture

Mouse model of enlarged vestibular aqueducts defines temporal requirement of Slc26a4 expression for hearing acquisition

Murine Surf4 is essential for early embryonic development

Mutations in RELT cause autosomal recessive amelogenesis imperfecta

Noncoding Microdeletion in Mouse Hgf Disrupts Neural Crest Migration into the Stria Vascularis, Reduces the Endocochlear Potential, and Suggests the Neuropathology for Human Nonsyndromic Deafness DFNB39

Normal TCR signal transduction in mice that lack catalytically active PTPN3 protein tyrosine phosphatase

Notch pathway targets proangiogenic regulator Sox17 to restrict angiogenesis

Obesity-Induced Infertility in Male Mice Is Associated With Disruption of Crisp4 Expression and Sperm Fertilization Capacity.

Pituitary hypoplasia and respiratory distress syndrome in Prop1 knockout mice

Pituitary-specific Gata2 knockout: effects on gonadotrope and thyrotrope function

Pleiotropic phenotype of a genomic knock-in of an RGS-insensitive G184S Gnai2 allele

Podocyte depletion causes glomerulosclerosis: diphtheria toxin-induced podocyte depletion in rats expressing human diphtheria toxin receptor transgene

Podocyte-specific JAK2 overexpression worsens diabetic kidney disease in mice.

Podocyte-specific overexpression of GLUT1 surprisingly reduces mesangial matrix expansion in diabetic nephropathy in mice

Principles of Genetic Engineering

Production of the butyrylcholinesterase knockout mouse.

Purification of Bacterial Artificial Chromosome (BAC) DNA Prepared with the NucleoBond System

Purification of immunoprotective tumor antigens by preparative isotachophoresis.

RNF8-dependent histone modifications regulate nucleosome removal during spermatogenesis

Rederivation of transgenic and gene-targeted mice by embryo transfer.

Reporter molecules in genetically engineered mice

Resistance to organophosphorus agent toxicity in transgenic mice expressing the G117H mutant of human butyrylcholinesterase.

Ribosomal protein L24 defect in belly spot and tail (Bst), a mouse Minute

Role of Complement in a Rat Model of Paclitaxel-Induced Peripheral Neuropathy

SAG/RBX2/ROC2 E3 Ubiquitin Ligase Is Essential for Vascular and Neural Development by Targeting NF1 for Degradation ⬇️

SRA gene knockout protects against diet-induced obesity and improves glucose tolerance

Secreted versus membrane-anchored collagenases: relative roles in fibroblast-dependent collagenolysis and invasion.

Sensitized mutagenesis screen in Factor V Leiden mice identifies thrombosis suppressor loci.

Sexually dimorphic distribution of Prokr2 neurons revealed by the Prokr2-Cre mouse model