Lista de obras - Simon P. Graham - Dominio Público Uruguay

A comparative study of the local cytokine response in the lungs of pigs experimentally infected with different PRRSV-1 strains: upregulation of IL-1α in highly pathogenic strain induced lesions

artículo científico publicado en 2015

A novel strategy for the identification of antigens that are recognised by bovine MHC class I restricted cytotoxic T cells in a protozoan infection using reverse vaccinology

artículo científico publicado en 2007

Analysis of the transcriptome of the protozoan Theileria parva using MPSS reveals that the majority of genes are transcriptionally active in the schizont stage

artículo científico publicado en 2005

Assessment of the enhancement of PLGA nanoparticle uptake by dendritic cells through the addition of natural receptor ligands and monoclonal antibody

artículo científico publicado en 2015

Assessment of the phenotype and functionality of porcine CD8 T cell responses following vaccination with live attenuated classical swine fever virus (CSFV) and virulent CSFV challenge.

artículo científico publicado en 2013

Bovine Herpesvirus-4-Vectored Delivery of Nipah Virus Glycoproteins Enhances T Cell Immunogenicity in Pigs

scientific article published on 02 March 2020

Bovine Pestivirus Heterogeneity and Its Potential Impact on Vaccination and Diagnosis

artículo científico publicado en 2020

CD1- and CD1+ porcine blood dendritic cells are enriched for the orthologues of the two major mammalian conventional subsets

artículo científico publicado en 2017

CD8 T-cell responses against the immunodominant Theileria parva peptide Tp249-59 are composed of two distinct populations specific for overlapping 11-mer and 10-mer epitopes.

artículo científico publicado en 2016

CD8+ T-cell responses to Theileria parva are preferentially directed to a single dominant antigen: Implications for parasite strain-specific immunity

artículo científico publicado en 2009

Cellular and Humoral Immune Responses after Immunisation with Low Virulent African Swine Fever Virus in the Large White Inbred Babraham Line and Outbred Domestic Pigs

scientific article published on 08 July 2022

Challenge of pigs with classical swine fever viruses after C-strain vaccination reveals remarkably rapid protection and insights into early immunity

artículo científico publicado en 2012

Challenges in Veterinary Vaccine Development and Immunization

artículo científico publicado en 2016

Characterisation of experimental infections of domestic pigs with genotype 2.1 and 3.3 isolates of classical swine fever virus.

artículo científico publicado en 2009

Characterisation of vaccine-induced, broadly cross-reactive IFN-γ secreting T cell responses that correlate with rapid protection against classical swine fever virus

artículo científico publicado en 2012

Characterisation of virus-specific peripheral blood cell cytokine responses following vaccination or infection with classical swine fever viruses

artículo científico publicado en 2009

Characterization of efferent lymph cells and their function following immunization of cattle with an allogenic Theileria annulata infected cell line.

artículo científico publicado en 2003

Characterization of the Myeloid Cell Populations' Resident in the Porcine Palatine Tonsil

Characterization of the fine specificity of bovine CD8 T-cell responses to defined antigens from the protozoan parasite Theileria parva

artículo científico publicado en 2007

Characterization of the interaction of African swine fever virus with monocytes and derived macrophage subsets

artículo científico publicado en 2016

Comparative analysis of cytokine transcript profiles within mediastinal lymph node compartments of pigs after infection with porcine reproductive and respiratory syndrome genotype 1 strains differing in pathogenicity

artículo científico publicado en 2015

Comparative analysis of immune responses following experimental infection of pigs with European porcine reproductive and respiratory syndrome virus strains of differing virulence

artículo científico publicado en 2012

Comparative phenotypic and functional analyses of the effects of autologous plasma and recombinant human macrophage-colony stimulating factor (M-CSF) on porcine monocyte to macrophage differentiation

artículo científico publicado en 2017

Comparison of Macrophage Responses to African Swine Fever Viruses Reveals that the NH/P68 Strain is Associated with Enhanced Sensitivity to Type I IFN and Cytokine Responses from Classically Activated Macrophages

artículo científico publicado en 2020

Comparison of the Immunogenicities and Cross-Lineage Efficacies of Live Attenuated Peste des Petits Ruminants Virus Vaccines PPRV/Nigeria/75/1 and PPRV/Sungri/96

artículo científico publicado en 2018

Design and evaluation of the immunogenicity and efficacy of a biomimetic particulate formulation of viral antigens

artículo científico publicado en 2017

Differential lung NK cell responses in avian influenza virus infected chickens correlate with pathogenicity

artículo científico publicado en 2013

Distinct response kinetics of gamma interferon and interleukin-4 in bovine tuberculosis.

artículo científico publicado en 2000

Down-regulated lymphoproliferation coincides with parasite maturation and with the collapse of both gamma interferon and interleukin-4 responses in a bovine model of onchocerciasis

artículo científico publicado en 2001

Early responses of natural killer cells in pigs experimentally infected with 2009 pandemic H1N1 influenza A virus

artículo científico publicado en 2014

Enhanced infectivity of H5N1 highly pathogenic avian influenza (HPAI) virus in pig ex vivo respiratory tract organ cultures following adaptation by in vitro passage

artículo científico publicado en 2013

Establishing Porcine Monocyte-Derived Macrophage and Dendritic Cell Systems for Studying the Interaction with PRRSV-1.

artículo científico publicado en 2016

Establishment of Systems to Enable Isolation of Porcine Monoclonal Antibodies Broadly Neutralizing the Porcine Reproductive and Respiratory Syndrome Virus

artículo científico publicado en 2019

Establishment of a Bovine Viral Diarrhea Virus Type 2 Intranasal Challenge Model for Assessing Vaccine Efficacy.

artículo científico publicado en 2018

Establishment of a Pig Influenza Challenge Model for Evaluation of Monoclonal Antibody Delivery Platforms

artículo científico publicado en 2020

Evaluation of Molecularly Imprinted Polymers as Synthetic Virus Neutralizing Antibody Mimics.

artículo científico publicado en 2019

Evaluation of hydrophobic chitosan-based particulate formulations of porcine reproductive and respiratory syndrome virus vaccine candidate T cell antigens

artículo científico publicado en 2017

Evaluation of the immunogenicity of prime-boost vaccination with the replication-deficient viral vectored COVID-19 vaccine candidate ChAdOx1 nCoV-19

artículo científico publicado en 2020

Evaluation of the recognition of Theileria parva vaccine candidate antigens by cytotoxic T lymphocytes from Zebu cattle

artículo científico publicado en 2007

Extensive polymorphism and evidence of immune selection in a highly dominant antigen recognized by bovine CD8 T cells specific for Theileria annulata

artículo científico publicado en 2011

Fusion of a cell penetrating peptide from HIV-1 TAT to the Theileria parva antigen Tp2 enhances the stimulation of bovine CD8+ T cell responses

artículo científico publicado en 2009

Head Start Immunity: Characterizing the Early Protection of C Strain Vaccine Against Subsequent Classical Swine Fever Virus Infection

artículo científico publicado en 2019

Host-pathogen interactions during porcine reproductive and respiratory syndrome virus 1 infection of piglets

artículo científico

Immunostimulatory CpG oligodeoxynucleotides enhance the induction of bovine CD4+ cytotoxic T-lymphocyte responses against the polymorphic immunodominant molecule of the protozoan parasite Theileria parva

artículo científico publicado en 2006

In a bovine model of onchocerciasis, protective immunity exists naturally, is absent in drug-cured hosts, and is induced by vaccination

artículo científico publicado en 2006

Increased pathogenicity of European porcine reproductive and respiratory syndrome virus is associated with enhanced adaptive responses and viral clearance

artículo científico publicado en 2012

Infection of monocytes with European porcine reproductive and respiratory syndrome virus (PRRSV-1) strain Lena is significantly enhanced by dexamethasone and IL-10.

artículo científico publicado en 2018

Interaction of porcine monocyte-derived dendritic cells with African swine fever viruses of diverse virulence.

artículo científico publicado en 2018

Is 'timing' important for cytokine polarization?

artículo científico publicado en 2002

Limited genetic and antigenic diversity within parasite isolates used in a live vaccine against Theileria parva.

artículo científico publicado en 2016

MHC Class I Bound to an Immunodominant Theileria parva Epitope Demonstrates Unconventional Presentation to T Cell Receptors

artículo científico publicado en 2010

Partial Activation of natural killer and γδ T cells by classical swine fever viruses is associated with type I interferon elicited from plasmacytoid dendritic cells.

artículo científico publicado en 2014

Pathology and Virus Distribution in the Lung and Lymphoid Tissues of Pigs Experimentally Inoculated with Three Distinct Type 1 PRRS Virus Isolates of Varying Pathogenicity

artículo científico publicado en 2014

Patterns of Onchocerca volvulus recombinant antigen recognition in a bovine model of onchocerciasis.

artículo científico publicado en 1999

Porcine Dendritic Cells and Viruses: An Update.

artículo científico publicado en 2019

Porcine reproductive and respiratory syndrome type 1 viruses induce hypoplasia of erythroid cells and myeloid cell hyperplasia in the bone marrow of experimentally infected piglets independently of the viral load and virulence.

artículo científico publicado en 2017

Proinflammatory cytokine expression by Theileria annulata infected cell lines correlates with the pathology they cause in vivo.

artículo científico publicado en 2001

Proteome-wide screening of the European porcine reproductive and respiratory syndrome virus reveals a broad range of T cell antigen reactivity

artículo científico publicado en 2014

Proteome-wide screening reveals immunodominance in the CD8 T cell response against classical swine fever virus with antigen-specificity dependent on MHC class I haplotype expression

artículo científico publicado en 2013

Recent advances in veterinary applications of structural vaccinology.

artículo científico publicado en 2018

Recombinant ovine interferon gamma inhibits the multiplication of Chlamydia psittaci in ovine cells.

artículo científico publicado en 1995

The MHC homozygous inbred Babraham pig as a resource for veterinary and translational medicine.

artículo científico publicado en 2018

The Non-structural Protein 5 and Matrix Protein Are Antigenic Targets of T Cell Immunity to Genotype 1 Porcine Reproductive and Respiratory Syndrome Viruses

artículo científico publicado en 2016

The bovine CD1D gene has an unusual gene structure and is expressed but cannot present α-galactosylceramide with a C26 fatty acid

artículo científico publicado en 2012

Theileria parva candidate vaccine antigens recognized by immune bovine cytotoxic T lymphocytes

artículo científico publicado en 2006

Thymic depletion of lymphocytes is associated with the virulence of PRRSV-1 strains

artículo científico publicado en 2016

Transient transfection of Theileria annulata

artículo científico publicado en 2001

Treatment of cattle with DNA-encoded Flt3L and GM-CSF prior to immunization with Theileria parva candidate vaccine antigens induces CD4 and CD8 T cell IFN-γ responses but not CTL responses

artículo científico publicado en 2011

Two Theileria parva CD8 T cell antigen genes are more variable in buffalo than cattle parasites, but differ in pattern of sequence diversity

artículo científico publicado en 2011

Vaccine Development for Nipah Virus Infection in Pigs

article

Lista de obras de Simon P. Graham

A comparative study of the local cytokine response in the lungs of pigs experimentally infected with different PRRSV-1 strains: upregulation of IL-1α in highly pathogenic strain induced lesions

A novel strategy for the identification of antigens that are recognised by bovine MHC class I restricted cytotoxic T cells in a protozoan infection using reverse vaccinology

Analysis of the transcriptome of the protozoan Theileria parva using MPSS reveals that the majority of genes are transcriptionally active in the schizont stage

Assessment of the enhancement of PLGA nanoparticle uptake by dendritic cells through the addition of natural receptor ligands and monoclonal antibody

Assessment of the phenotype and functionality of porcine CD8 T cell responses following vaccination with live attenuated classical swine fever virus (CSFV) and virulent CSFV challenge.

Bovine Herpesvirus-4-Vectored Delivery of Nipah Virus Glycoproteins Enhances T Cell Immunogenicity in Pigs

Bovine Pestivirus Heterogeneity and Its Potential Impact on Vaccination and Diagnosis

CD1- and CD1+ porcine blood dendritic cells are enriched for the orthologues of the two major mammalian conventional subsets

CD8 T-cell responses against the immunodominant Theileria parva peptide Tp249-59 are composed of two distinct populations specific for overlapping 11-mer and 10-mer epitopes.

CD8+ T-cell responses to Theileria parva are preferentially directed to a single dominant antigen: Implications for parasite strain-specific immunity

Cellular and Humoral Immune Responses after Immunisation with Low Virulent African Swine Fever Virus in the Large White Inbred Babraham Line and Outbred Domestic Pigs

Challenge of pigs with classical swine fever viruses after C-strain vaccination reveals remarkably rapid protection and insights into early immunity

Challenges in Veterinary Vaccine Development and Immunization

Characterisation of experimental infections of domestic pigs with genotype 2.1 and 3.3 isolates of classical swine fever virus.

Characterisation of vaccine-induced, broadly cross-reactive IFN-γ secreting T cell responses that correlate with rapid protection against classical swine fever virus

Characterisation of virus-specific peripheral blood cell cytokine responses following vaccination or infection with classical swine fever viruses

Characterization of efferent lymph cells and their function following immunization of cattle with an allogenic Theileria annulata infected cell line.

Characterization of the Myeloid Cell Populations' Resident in the Porcine Palatine Tonsil

Characterization of the fine specificity of bovine CD8 T-cell responses to defined antigens from the protozoan parasite Theileria parva

Characterization of the interaction of African swine fever virus with monocytes and derived macrophage subsets

Comparative analysis of cytokine transcript profiles within mediastinal lymph node compartments of pigs after infection with porcine reproductive and respiratory syndrome genotype 1 strains differing in pathogenicity

Comparative analysis of immune responses following experimental infection of pigs with European porcine reproductive and respiratory syndrome virus strains of differing virulence

Comparative phenotypic and functional analyses of the effects of autologous plasma and recombinant human macrophage-colony stimulating factor (M-CSF) on porcine monocyte to macrophage differentiation

Comparison of Macrophage Responses to African Swine Fever Viruses Reveals that the NH/P68 Strain is Associated with Enhanced Sensitivity to Type I IFN and Cytokine Responses from Classically Activated Macrophages

Comparison of the Immunogenicities and Cross-Lineage Efficacies of Live Attenuated Peste des Petits Ruminants Virus Vaccines PPRV/Nigeria/75/1 and PPRV/Sungri/96

Design and evaluation of the immunogenicity and efficacy of a biomimetic particulate formulation of viral antigens

Differential lung NK cell responses in avian influenza virus infected chickens correlate with pathogenicity

Distinct response kinetics of gamma interferon and interleukin-4 in bovine tuberculosis.

Down-regulated lymphoproliferation coincides with parasite maturation and with the collapse of both gamma interferon and interleukin-4 responses in a bovine model of onchocerciasis

Early responses of natural killer cells in pigs experimentally infected with 2009 pandemic H1N1 influenza A virus

Enhanced infectivity of H5N1 highly pathogenic avian influenza (HPAI) virus in pig ex vivo respiratory tract organ cultures following adaptation by in vitro passage

Establishing Porcine Monocyte-Derived Macrophage and Dendritic Cell Systems for Studying the Interaction with PRRSV-1.

Establishment of Systems to Enable Isolation of Porcine Monoclonal Antibodies Broadly Neutralizing the Porcine Reproductive and Respiratory Syndrome Virus

Establishment of a Bovine Viral Diarrhea Virus Type 2 Intranasal Challenge Model for Assessing Vaccine Efficacy.

Establishment of a Pig Influenza Challenge Model for Evaluation of Monoclonal Antibody Delivery Platforms

Evaluation of Molecularly Imprinted Polymers as Synthetic Virus Neutralizing Antibody Mimics.

Evaluation of hydrophobic chitosan-based particulate formulations of porcine reproductive and respiratory syndrome virus vaccine candidate T cell antigens

Evaluation of the immunogenicity of prime-boost vaccination with the replication-deficient viral vectored COVID-19 vaccine candidate ChAdOx1 nCoV-19

Evaluation of the recognition of Theileria parva vaccine candidate antigens by cytotoxic T lymphocytes from Zebu cattle

Extensive polymorphism and evidence of immune selection in a highly dominant antigen recognized by bovine CD8 T cells specific for Theileria annulata

Fusion of a cell penetrating peptide from HIV-1 TAT to the Theileria parva antigen Tp2 enhances the stimulation of bovine CD8+ T cell responses

Head Start Immunity: Characterizing the Early Protection of C Strain Vaccine Against Subsequent Classical Swine Fever Virus Infection

Host-pathogen interactions during porcine reproductive and respiratory syndrome virus 1 infection of piglets

Immunostimulatory CpG oligodeoxynucleotides enhance the induction of bovine CD4+ cytotoxic T-lymphocyte responses against the polymorphic immunodominant molecule of the protozoan parasite Theileria parva

In a bovine model of onchocerciasis, protective immunity exists naturally, is absent in drug-cured hosts, and is induced by vaccination

Increased pathogenicity of European porcine reproductive and respiratory syndrome virus is associated with enhanced adaptive responses and viral clearance

Infection of monocytes with European porcine reproductive and respiratory syndrome virus (PRRSV-1) strain Lena is significantly enhanced by dexamethasone and IL-10.

Interaction of porcine monocyte-derived dendritic cells with African swine fever viruses of diverse virulence.

Is 'timing' important for cytokine polarization?

Limited genetic and antigenic diversity within parasite isolates used in a live vaccine against Theileria parva.

MHC Class I Bound to an Immunodominant Theileria parva Epitope Demonstrates Unconventional Presentation to T Cell Receptors

Partial Activation of natural killer and γδ T cells by classical swine fever viruses is associated with type I interferon elicited from plasmacytoid dendritic cells.

Pathology and Virus Distribution in the Lung and Lymphoid Tissues of Pigs Experimentally Inoculated with Three Distinct Type 1 PRRS Virus Isolates of Varying Pathogenicity

Patterns of Onchocerca volvulus recombinant antigen recognition in a bovine model of onchocerciasis.

Porcine Dendritic Cells and Viruses: An Update.

Porcine reproductive and respiratory syndrome type 1 viruses induce hypoplasia of erythroid cells and myeloid cell hyperplasia in the bone marrow of experimentally infected piglets independently of the viral load and virulence.

Proinflammatory cytokine expression by Theileria annulata infected cell lines correlates with the pathology they cause in vivo.

Proteome-wide screening of the European porcine reproductive and respiratory syndrome virus reveals a broad range of T cell antigen reactivity

Proteome-wide screening reveals immunodominance in the CD8 T cell response against classical swine fever virus with antigen-specificity dependent on MHC class I haplotype expression

Recent advances in veterinary applications of structural vaccinology.

Recombinant ovine interferon gamma inhibits the multiplication of Chlamydia psittaci in ovine cells.

The MHC homozygous inbred Babraham pig as a resource for veterinary and translational medicine.

The Non-structural Protein 5 and Matrix Protein Are Antigenic Targets of T Cell Immunity to Genotype 1 Porcine Reproductive and Respiratory Syndrome Viruses

The bovine CD1D gene has an unusual gene structure and is expressed but cannot present α-galactosylceramide with a C26 fatty acid

Theileria parva candidate vaccine antigens recognized by immune bovine cytotoxic T lymphocytes

Thymic depletion of lymphocytes is associated with the virulence of PRRSV-1 strains

Transient transfection of Theileria annulata

Treatment of cattle with DNA-encoded Flt3L and GM-CSF prior to immunization with Theileria parva candidate vaccine antigens induces CD4 and CD8 T cell IFN-γ responses but not CTL responses

Two Theileria parva CD8 T cell antigen genes are more variable in buffalo than cattle parasites, but differ in pattern of sequence diversity

Vaccine Development for Nipah Virus Infection in Pigs